Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccc(F)cn3)cn12 CHEMBL3930178 IC50 1.0 nM
COCCN1CCC(Nc2nc(-c3nc4cc(C5=NNC(=O)CC5C)ccc4n3Cc3ccccc3)cn3c(C)nnc23)CC1 CHEMBL3938152 IC50 3.0 nM
CNc1nc(-c2nc3cnc(N4CCOCC4)cc3n2Cc2ccccn2)cn2c(C)nnc12 CHEMBL3953268 IC50 3.0 nM
CNc1nc(-c2nc3ccc(N4CCOCC4)cc3n2Cc2ccccn2)cn2c(C)nnc12 CHEMBL3916639 IC50 3.0 nM
CNc1nc(-c2nc(-c3ccccc3)c(C)n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3979803 IC50 4.0 nM
CNc1nc(-c2nc3cnc(N4CCOCC4)cc3n2Cc2cccnc2)cn2c(C)nnc12 CHEMBL3959499 IC50 4.0 nM
CNc1nc(-c2nc3cc(C4=NNC(=O)CC4C)ccc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3913643 IC50 5.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4ccc(N5CCOCC5)cc4n3Cc3ccccn3)cn12 CHEMBL3939182 IC50 5.0 nM
CNc1nc(-c2nc3ccc(N4CCOCC4)cc3n2Cc2cccnc2)cn2c(C)nnc12 CHEMBL3935504 IC50 5.0 nM
Cc1nnc2c(NC3CCN(C)CC3)nc(-c3nc4ccccc4n3Cc3ccccc3)cn12 CHEMBL3983932 IC50 7.0 nM
COCCN1CCC(Nc2nc(-c3nc4ccc(N5CCOCC5)cc4n3Cc3ccccc3)cn3c(C)nnc23)CC1 CHEMBL3920322 IC50 7.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4ccc(N(C)C)cc4n3Cc3ccccn3)cn12 CHEMBL3923899 IC50 7.0 nM
CNc1nc(-c2nn(C)c(C)c2Oc2ccccc2)cn2c(C)nnc12 CHEMBL3929450 IC50 8.0 nM
COCCN1CCC(Nc2nc(-c3nc4ccccc4n3Cc3ccccc3)cn3c(C)nnc23)CC1 CHEMBL3923105 IC50 8.0 nM
CNc1nc(-c2nc3ccc(N4CCN(C)CC4)cc3n2Cc2ccccn2)cn2c(C)nnc12 CHEMBL3929086 IC50 8.0 nM
CNc1nc(-c2nc3ccc(N4CCN(C)CC4)cc3n2Cc2cccnc2)cn2c(C)nnc12 CHEMBL3927028 IC50 8.0 nM
COCCN1CCC(Nc2nc(-c3nc4ccccc4n3Cc3ccc(F)cc3)cn3c(C)nnc23)CC1 CHEMBL3941148 IC50 9.0 nM
COCCN1CCC(Nc2nc(-c3nc4ccccc4n3Cc3ccc(F)c(F)c3)cn3c(C)nnc23)CC1 CHEMBL3970690 IC50 9.0 nM
CNc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3908717 IC50 9.0 nM
CNc1nc(-c2nc3cnc(N4CCN(C)CC4)nc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3951550 IC50 9.0 nM
CNc1nc(-c2nc3ccc(N4CCN(C)CC4)cc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3919831 IC50 9.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOC[C@H]5C)cc4n3Cc3ccccn3)cn12 CHEMBL4112988 IC50 9.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOC[C@@H]5C)cc4n3Cc3ccccn3)cn12 CHEMBL3893231 IC50 9.0 nM
CNc1nc(-c2nc3ccc(N4CCOCC4)cc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3914807 IC50 10.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccccn3)cn12 CHEMBL3902208 IC50 10.0 nM
CNc1nc(-c2nc3cc(C4CCOCC4)ccc3n2Cc2ccccn2)cn2c(C)nnc12 CHEMBL3907651 IC50 11.0 nM
CNc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2cccnc2)cn2c(C)nnc12 CHEMBL3973914 IC50 12.0 nM
CNc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2ccncc2)cn2c(C)nnc12 CHEMBL3966649 IC50 12.0 nM
CNc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2ccccn2)cn2c(C)nnc12 CHEMBL3928047 IC50 13.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N(C)C)cc4n3Cc3ccccn3)cn12 CHEMBL3951605 IC50 13.0 nM
Cc1nnc2c(N[C@@H]3CCOC3)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3cccnc3)cn12 CHEMBL4114198 IC50 13.0 nM
Cc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3919702 IC50 14.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnccc4n3Cc3ccccn3)cn12 CHEMBL3946335 IC50 14.0 nM
CNc1nc(-c2nc(C)c(C)n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3916156 IC50 15.0 nM
Cc1ccc2nc(-c3cn4c(C)nnc4c(NC(C)C)n3)n(Cc3ccccn3)c2c1 CHEMBL3937464 IC50 15.0 nM
CCNc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3956797 IC50 17.0 nM
Cc1cccc(Cn2c(-c3cn4c(C)nnc4c(NC(C)C)n3)nc3cnc(N4CCOCC4)cc32)n1 CHEMBL3914869 IC50 17.0 nM
CNc1nc(-c2nn(C)c(C)c2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3891629 IC50 18.0 nM
CNc1nc(-c2nc3cccnc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3947502 IC50 18.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(C(C)C)cc4n3Cc3ccccn3)cn12 CHEMBL3956941 IC50 18.0 nM
Cc1nnc2c(N[C@@H]3CCOC3)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccccn3)cn12 CHEMBL4115491 IC50 20.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4ccccc4n3Cc3ccccn3)cn12 CHEMBL3960315 IC50 20.0 nM
CNc1nc(-c2nc3ccccc3n2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3946480 IC50 22.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCN(C)CC5)cc4n3Cc3ccccc3)cn12 CHEMBL3929241 IC50 26.0 nM
Cc1cc2c(cn1)nc(-c1cn3c(C)nnc3c(NC(C)C)n1)n2Cc1ccccn1 CHEMBL3909523 IC50 28.0 nM
Cc1nc(-c2cn3c(C)nnc3c(C)n2)n(Cc2ccccc2)c1C CHEMBL3985926 IC50 31.0 nM
Cc1cc2c(cn1)nc(-c1cn3c(C)nnc3c(N[C@@H]3CCOC3)n1)n2Cc1cccnc1 CHEMBL4107079 IC50 31.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4ccc(C5CCOCC5)cc4n3Cc3ccccn3)cn12 CHEMBL3916033 IC50 32.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(C5CCOCC5)cc4n3Cc3ccccn3)cn12 CHEMBL3987136 IC50 34.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOC[C@@H]5C)cc4n3[C@@H](C)c3ccccc3)cn12 CHEMBL3959056 IC50 38.0 nM
CNc1nc(-c2cnn(C)c2Oc2ccccc2)cn2c(C)nnc12 CHEMBL3951768 IC50 41.0 nM
Cc1nc(-c2cnn(C)c2Oc2ccccc2)cn2c(C)nnc12 CHEMBL3924063 IC50 41.0 nM
COCCN1CCC(Nc2nc(-c3nc4ccccc4n3[C@@H](C)c3ccccc3)cn3c(C)nnc23)CC1 CHEMBL3898582 IC50 41.0 nM
COc1ccc2nc(-c3cn4c(C)nnc4c(NC(C)C)n3)n(Cc3ccccn3)c2c1 CHEMBL3936354 IC50 45.0 nM
COCCN1CCC(Nc2nc(-c3nc4ccccc4n3[C@H](C)c3ccccc3)cn3c(C)nnc23)CC1 CHEMBL4107020 IC50 49.0 nM
CNc1nc(-c2cn(C)nc2Cc2ccccc2)cn2c(C)nnc12 CHEMBL3961767 IC50 61.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(C(C)C)cc4n3[C@@H](C)c3ccccn3)cn12 CHEMBL3972925 IC50 66.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4ccc(C5CCOCC5)cc4n3[C@@H](C)c3ccccn3)cn12 CHEMBL3964764 IC50 69.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOC[C@@H]5C)cc4n3[C@@H](C)c3ccccn3)cn12 CHEMBL3898305 IC50 74.0 nM
COc1cc2c(cn1)nc(-c1cn3c(C)nnc3c(NC(C)C)n1)n2Cc1ccccn1 CHEMBL3985602 IC50 126.0 nM
Cc1nnc2c(NC(C)C)nc(-c3nc4ccc(C(C)C)cc4n3[C@@H](C)c3ccccn3)cn12 CHEMBL3949777 IC50 243.0 nM