NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)c(-c4cccc(Oc5[nH]nnc5C(=O)O)c4)c3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F CHEMBL4855986 IC50 0.9 nM
NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)c(-c4ccc(Sc5nn[nH]c5C(=O)O)cc4)c3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F CHEMBL4861379 IC50 1.1 nM
NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)c(-c4ccc(Oc5nn[nH]c5C(=O)O)cc4)c3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F CHEMBL4850573 IC50 1.2 nM
NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)c(-c4ccc(-c5nn[nH]c5C(=O)O)cc4)c3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F CHEMBL4847068 IC50 3.6 nM
NS(=O)(=O)c1ccc(Cc2c(-c3cccc(Sc4[nH]nnc4C(=O)O)c3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F CHEMBL4864519 IC50 4.7 nM
O=C(O)c1[nH]nnc1Sc1ccc(Cl)cc1 CHEMBL4857427 IC50 6.7 nM
NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)c(Oc4[nH]nnc4C(=O)O)c3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F CHEMBL4873879 IC50 11.0 nM
CCCCCCCCCCCCSc1[nH]nnc1C(=O)O CHEMBL1229989 Ki 15.0 nM
CN(C)c1noc(-c2cccc(CN(C)c3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5086346 IC50 21.0 nM
Cc1csc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5078184 IC50 23.0 nM
CCN(Cc1cccc(-c2nc(N(C)C)no2)c1O)c1ccc2[nH]nc(C(=O)O)c2c1 CHEMBL5090889 IC50 24.0 nM
Cc1nc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)sc1C CHEMBL5083082 IC50 25.0 nM
CC(C)c1csc(-c2cccc(CN(C)c3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5079217 IC50 35.0 nM
CC(C)N(Cc1cccc(-c2nc(N(C)C)no2)c1O)c1ccc2[nH]nc(C(=O)O)c2c1 CHEMBL5080894 IC50 35.0 nM
CN(C)c1noc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5081182 IC50 37.0 nM
CC(C)c1noc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5077149 IC50 47.0 nM
O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(SCC3(O)COc4ccccc4OC3)cc2)cc1 CHEMBL18295 I50 60.0 nM
O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(Br)cc2)cc1 CHEMBL282504 I50 63.0 nM
CC(C)c1csc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5084900 IC50 65.0 nM
CC(C)c1coc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5079471 IC50 87.0 nM
O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(SCCc3ccncc3)cc2)cc1 CHEMBL273783 I50 90.0 nM
CN(Cc1ccc(F)cc1-c1ccc(C(=O)O)c(Cl)c1)C(=O)c1cc2ccc(Cl)cc2[nH]1 CHEMBL5090196 IC50 110.0 nM
O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(S)cc2)cc1 CHEMBL428525 I50 130.0 nM
CSc1ccc(-c2ccc(C(=O)CC(=O)C(=O)O)cc2)cc1 CHEMBL18721 I50 160.0 nM
CN(C)c1noc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2)n1 CHEMBL5075215 IC50 170.0 nM
O=C(O)C(=O)CC(=O)c1ccc(-n2c(-c3ccccc3)cc3ccccc32)cc1 CHEMBL276330 I50 180.0 nM
CN(C)c1noc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2Cl)n1 CHEMBL5080981 IC50 180.0 nM
O=C1NC(=O)C(c2ccc(-c3ccc(Br)cc3)cc2)C1=O CHEMBL5078643 IC50 190.0 nM
Cc1nc(-c2cccc(CN(C)c3ccc4[nH]nc(C(=O)O)c4c3)c2)sc1C CHEMBL5072756 IC50 290.0 nM
O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(SCc3ccccc3)cc2)cc1 CHEMBL19036 I50 400.0 nM
O=C(O)C(=O)CC(=O)c1ccc(Cc2ccc(Cl)c(Cl)c2)cc1 CHEMBL18672 I50 440.0 nM
CCCOc1ncccc1CN(C)c1ccc2[nH]nc(C(=O)O)c2c1 CHEMBL5075958 IC50 510.0 nM
CCCCCCCCCc1ccc(C(=O)CC(=O)C(=O)O)cc1 CHEMBL282502 I50 600.0 nM
Cc1csc(-c2cccc(CN(C)c3ccc4[nH]nc(C(=O)O)c4c3)c2)n1 CHEMBL5084629 IC50 650.0 nM
CC(C)c1csc(-c2cccc(CN(C)c3ccc4[nH]nc(C(=O)O)c4c3)c2)n1 CHEMBL5078345 IC50 710.0 nM
CC(C)n1ccc(-c2cccc(CNc3ccc4[nH]nc(C(=O)O)c4c3)c2O)n1 CHEMBL5085053 IC50 860.0 nM