C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC(=O)C[C@@H](NC(=O)CCCCCNC(=O)[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O)C(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](CCCCN)C(N)=O)[C@H](C)O CHEMBL5199572 Kd 0.019 nM
C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC(=O)C[C@@H](NC(=O)CCCCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)C(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)[C@H](C)O CHEMBL5194339 Kd 0.42 nM
Cc1c[nH]c(CNC(=O)c2ccc(-c3nc4ccc5[nH]ncc5c4c4c3CCCC4)cc2)n1 CHEMBL5440655 Kd 0.55 nM
CCn1c(C(N)=O)cc2c1-c1ccncc1OC2(C)C CHEMBL4791276 IC50 1.6 nM
CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1 CHEMBL5178368 IC50 2.0 nM
CC1(N)CCN(c2nn3c(-c4ccc(F)cc4F)cnc3s2)CC1 CHEMBL5201780 IC50 3.0 nM
Nc1ccc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5186093 IC50 3.0 nM
c1nc(N[C@H]2CC[C@H](N3CCOCC3)CC2)c2c(C3CCOCC3)c[nH]c2n1 CHEMBL4064608 IC50 4.0 nM
Nc1ncnc2c1c(I)cn2[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H]1O CHEMBL5169980 Kd 4.0 nM
COc1ccc(-c2cnc3sc(N[C@H]4CC[C@@H](N)CC4)nn23)cn1 CHEMBL5201904 IC50 5.0 nM
CC(C)(N)CNc1nn2c(-c3ccc(F)cc3F)cnc2s1 CHEMBL5179988 Kd 10.0 nM
Oc1ccc(-c2nc3ccc4[nH]ncc4c3c3c2CCCC3)c(F)c1 CHEMBL4278808 IC50 12.0 nM
CSc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5188318 IC50 12.0 nM
O=C1/C(=C/c2c[nH]c3ncccc23)Oc2cc(O)ccc21 CHEMBL4642838 IC50 14.0 nM
CN(C)c1nccc(-c2cnn3ncccc23)n1 CHEMBL4848254 Kd 15.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 19.0 nM
COc1ccc(-c2cnc3sc(N4CCC(C)(N)CC4)nn23)c(F)c1 CHEMBL5187817 IC50 32.0 nM
CN1CCC(CNc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 CHEMBL1952329 IC50 34.0 nM
O=C(Cc1ccc(F)cc1)Nc1cncc(-c2cc(-c3cccnc3)cs2)c1 CHEMBL4290247 IC50 36.0 nM
CC1(N)CCN(c2nn3c(C4=CCCCC4)cnc3s2)CC1 CHEMBL5192443 IC50 45.0 nM
COc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5181620 IC50 50.0 nM
CC(C)Sc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5177344 IC50 56.0 nM
CCCSc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5194011 IC50 65.0 nM
CCCCSc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5186471 IC50 69.0 nM
O=C(Nc1cncc(-c2cc(-c3cccnc3)cs2)c1)C1CC1 CHEMBL4283503 IC50 76.3 nM
O=C1/C(=C/c2c[nH]c3ncccc23)CCc2cc(O)ccc21 CHEMBL4637707 IC50 77.0 nM
COc1cccc(-c2cnc3sc(N4CCC(C)(N)CC4)nn23)n1 CHEMBL5187610 IC50 78.0 nM
COCCNC(=O)c1ccc(Oc2sc(C(N)=O)c3c2-c2sncc2CC3)cn1 CHEMBL4066819 Kd 86.0 nM
CCSc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5196946 IC50 91.0 nM
COc1ccc2c3ccnc(C(F)(F)F)c3n(CCCCN)c2c1 CHEMBL2012574 IC50 100.0 nM
CC(C)c1ccn2ncnc(N[C@H]3CC[C@@H](N4CCN(C(=O)CCC(=O)N5CCC(CCN6CCN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)CC5)CC4)CC3)c12 CHEMBL4749646 IC50 110.0 nM
CC(C)Sc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5208358 IC50 114.0 nM
CSc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5183366 IC50 119.0 nM
CCSc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5202187 IC50 124.0 nM
C[C@@H](NC(=O)Nc1cc2[nH]ncc2c(CO)n1)c1ccccc1 CHEMBL4538174 Kd 130.0 nM
CC1(N)CCN(c2nn3c(C#CCO)cnc3s2)CC1 CHEMBL5170360 IC50 140.0 nM
CC(=O)N1CCN([C@H]2CC[C@@H](Nc3ncnn4ccc(C(C)C)c34)CC2)CC1 CHEMBL4744403 IC50 150.0 nM
C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC(=O)C[C@@H](NC(=O)CCCCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)C(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(N)=O)[C@@H](C)O CHEMBL5198165 Kd 150.0 nM
COc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5208474 IC50 159.0 nM
Cc1nccc2c3ccc(O)cc3n(CCCCN)c12 CHEMBL2012563 IC50 160.0 nM
CCCSc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5198375 IC50 169.0 nM
COc1ccc2c3ccnc(C)c3n(CCCCN)c2c1 CHEMBL2012559 IC50 170.0 nM
C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC(=O)C[C@@H](NC(=O)CCCCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)C(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(N)=O)[C@H](C)O CHEMBL5209851 Kd 170.0 nM
CCc1nccc2c3ccc(OC)cc3n(CCCCN)c12 CHEMBL2012562 IC50 190.0 nM
CN1CCN(c2ccc(-n3cc(-c4ccncc4OCC4CCNCC4)cn3)cc2)CC1 CHEMBL3824068 IC50 190.0 nM
CC1(N)CCN(c2nn3c(-c4cccc5cc[nH]c45)cnc3s2)CC1 CHEMBL5195201 IC50 200.0 nM
CCC(C)Sc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5190257 IC50 202.0 nM
COc1cccc2c3ccnc(C)c3n(CCCCN)c12 CHEMBL2012569 IC50 220.0 nM
NCCCCn1c2cc(O)ccc2c2ccnc(C(F)(F)F)c21 CHEMBL2012575 IC50 220.0 nM
O=C1NC(=S)S/C1=C\c1ccc2ncsc2c1 CHEMBL3775393 IC50 255.0 nM
O=C1NC(=S)S/C1=C\c1ccc2ncccc2c1 CHEMBL3774448 IC50 259.0 nM
COc1ccc2c3ccncc3n(CCCCN)c2c1 CHEMBL2012560 IC50 300.0 nM
CNCCCCn1c2cc(OC)ccc2c2ccnc(C)c21 CHEMBL2012572 IC50 340.0 nM
CCCCCSc1ncc2cc3cnccc3c(N)c2n1 CHEMBL5179862 IC50 432.0 nM
COc1ccc2c3ccnc(C)c3n(CCCN)c2c1 CHEMBL2012558 IC50 460.0 nM
COc1ccc2c3ccnc(C(C)C)c3n(CCCCN)c2c1 CHEMBL2012561 IC50 460.0 nM
COc1ccc2c3ccnc(C)c3n(CCCCN(C)C)c2c1 CHEMBL2012573 IC50 470.0 nM
CCC(C)Sc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5181571 IC50 484.0 nM
Cc1nccc2c3cc4c(cc3n(CCCCN)c12)OCO4 CHEMBL2012570 IC50 500.0 nM
Cc1nccc2c3ccc(F)cc3n(CCCCN)c12 CHEMBL2012564 IC50 580.0 nM
COc1ccc2c(c1)[nH]c1c(C)nccc12 CHEMBL269538 IC50 590.0 nM
Cc1nccc2c3ccc(NS(C)(=O)=O)cc3n(CCCCN)c12 CHEMBL2012565 IC50 690.0 nM
COc1nc(F)ccc1-c1cnc2sc(N3CCC(C)(N)CC3)nn12 CHEMBL5207627 IC50 690.0 nM
Cc1[nH]ccc2c1[nH]c1cc(=O)ccc12 CHEMBL486817 IC50 770.0 nM
COc1cccc(-c2cnc3sc(N4CCC(C)(N)CC4)nn23)c1F CHEMBL5204715 IC50 770.0 nM
Cc1nccc2c1[nH]c1cc(O)ccc12 CHEMBL14285 IC50 770.0 nM
COc1ccc2c3ccnc(C)c3n(CCCCN)c2c1Cl CHEMBL2012571 IC50 830.0 nM
CCOC(=O)CCSc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5181177 IC50 897.0 nM
CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(OC(F)F)c1 CHEMBL4872886 IC50 922.0 nM
CN1CCN(C(=O)c2ccc3cc(CCNc4ccnc5ccc(C#N)cc45)ccc3c2)CC1 CHEMBL4878072 Kd 1000.0 nM