COC(=O)/C=C/C(=O)O CHEMBL589586 IC50 0.96 nM
O=C(CCc1cnc(-c2ccc(O)cc2Cl)s1)Nc1ccccc1C(=O)O CHEMBL236162 IC50 1.0 nM
O=C(CCc1noc2c1ccc1c(Cl)c(O)ccc12)NC1=C(C(=O)O)CCCC1 CHEMBL483336 IC50 1.0 nM
O=C(CCc1cnn2c1ccc1cc(O)ccc12)NC1=C(C(=O)O)CCCC1 CHEMBL483337 IC50 1.0 nM
N[C@@H](Cc1nc(-c2ccc(O)cn2)no1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770352 IC50 1.0 nM
O=c1[nH]c(=O)c2c(CCC3CCC3)cc(=O)oc2[nH]1 CHEMBL2036954 EC50 1.0 nM
O=C(O)C1=C(NC(=O)C(F)(F)C(F)(F)c2nc(-c3ccc(O)cn3)no2)CCCC1 CHEMBL1084657 Ki 1.4 nM
CC1(CCCc2cc(=O)oc3[nH]c(=O)[nH]c(=O)c23)CC1 CHEMBL2036958 EC50 2.0 nM
O=C(CCc1noc2c1ccc1cc(O)ccc12)Nc1ccccc1C(=O)O CHEMBL520299 IC50 3.0 nM
O=C(CCc1noc2c1ccc1cc(O)ccc12)NC1=C(C(=O)O)CCCC1 CHEMBL483139 IC50 3.0 nM
O=C(CCc1nc(-c2ccc(O)cn2)no1)NC1=C(C(=O)O)CCCC1 CHEMBL1087302 Ki 3.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2cc(F)cc(F)c2)CC1 CHEMBL1083138 IC50 3.0 nM
O=c1[nH]c(=O)c2c(CCCC(F)F)cc(=O)oc2[nH]1 CHEMBL2036951 EC50 3.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2Cl)cc1)Nc1ccccc1C(=O)O CHEMBL235256 IC50 4.0 nM
O=C(CCc1nc(-c2ccc(O)cn2)no1)Nc1ccccc1C(=O)O CHEMBL237248 IC50 4.0 nM
O=C(CCc1noc2c1CCc1cc(O)ccc1-2)Nc1ccccc1C(=O)O CHEMBL483353 IC50 4.0 nM
O=C(CCc1noc2c1CCc1cc(O)ccc1-2)NC1=C(C(=O)O)CCCC1 CHEMBL485196 IC50 4.0 nM
CC(Cc1nc(-c2ccc(O)cn2)no1)C(=O)NC1=C(C(=O)O)CCCC1 CHEMBL1086656 Ki 4.0 nM
CC(C)(Cc1nc(-c2ccc(O)cn2)no1)C(=O)NC1=C(C(=O)O)CCCC1 CHEMBL1086657 Ki 4.0 nM
CCCC1CCC(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)C1 CHEMBL1084576 IC50 4.0 nM
N[C@H](Cc1nc(-c2ccc(O)cn2)no1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770353 IC50 4.0 nM
CC(C)CCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036948 EC50 4.0 nM
O=c1[nH]c(=O)c2c(CCCC3CC3)cc(=O)oc2[nH]1 CHEMBL2036955 EC50 4.0 nM
O=C(CCc1[nH]nc2c1ccc1cc(O)ccc12)Nc1ccccc1C(=O)O CHEMBL483352 IC50 5.0 nM
O=C(CCc1cn2c(n1)sc1cc(O)ccc12)NC1=C(C(=O)O)CCCC1 CHEMBL520513 IC50 5.0 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)NC1=C(C(=O)O)CC(c2cc(F)cc(F)c2)CC1 CHEMBL1085616 IC50 5.0 nM
O=C(CCc1ccn(-c2ccc(O)cn2)n1)NC1=C(C(=O)O)CCCC1 CHEMBL1085156 IC50 5.0 nM
N[C@@H](Cc1nc(-c2ccc(O)cn2)no1)C(=O)NC1=C(C(=O)O)CCCC1 CHEMBL1770355 IC50 5.0 nM
CC(C)CCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036950 EC50 5.0 nM
O=C(CCc1noc2c1ccc1c(F)c(O)ccc12)NC1=C(C(=O)O)CCCC1 CHEMBL483140 IC50 6.0 nM
CCCCC1CCC(NC(=O)CCc2ccc3cc(O)ccc3c2)=C(C(=O)O)C1 CHEMBL1086354 IC50 6.0 nM
C[C@H]1CC(NC(=O)CCc2nc(-c3ccc(F)cn3)no2)=C(C(=O)O)C[C@H]1c1cc(F)cc(F)c1F CHEMBL1084799 IC50 6.0 nM
C[C@H]1CC(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)C[C@H]1c1cc(F)cc(F)c1F CHEMBL1085589 EC50 6.0 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)NC1=C(C(=O)O)CCC(c2cccc(F)c2F)C1 CHEMBL1086541 IC50 6.0 nM
O=C(CCc1nc(-c2ccc(O)cn2)no1)NC1=C(C(=O)O)CC(c2cccc(F)c2)CC1 CHEMBL1084030 IC50 7.0 nM
Cc1c(CCC(=O)NC2=C(C(=O)O)CCCC2)cnn1-c1ccc(O)cn1 CHEMBL1085148 IC50 7.0 nM
O=c1[nH]c(=O)c2c(CCCC3(Cl)CC3)cc(=O)oc2[nH]1 CHEMBL2036960 EC50 7.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2cccc(F)c2)CC1 CHEMBL1085414 IC50 7.4 nM
O=C(O)c1n[nH]c2c1C[C@H]1[C@@H](CC3CC3)[C@@H]21 CHEMBL2057602 EC50 7.4 nM
O=C(CCc1ccc(-c2ccc(O)cc2Cl)s1)Nc1ccccc1C(=O)O CHEMBL235954 IC50 8.0 nM
O=C(CCc1nnn2c1ccc1cc(O)ccc12)Nc1ccccc1C(=O)O CHEMBL521326 IC50 8.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CCCC1 CHEMBL482698 IC50 8.0 nM
CCCC1CCC(NC(=O)CCc2ccc3cc(O)ccc3c2)=C(C(=O)O)C1 CHEMBL1086353 IC50 8.0 nM
C[C@H]1CC(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)C[C@H]1c1cccc(F)c1 CHEMBL1086225 IC50 8.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2ccc(F)cc2)CC1 CHEMBL1085655 IC50 8.6 nM
O=C(O)c1cccnc1 CHEMBL573 Log EC50 8.71 nM
O=C(CCc1ccc(-c2ccc(O)cn2)cc1)Nc1ccccc1C(=O)O CHEMBL235952 IC50 9.0 nM
O=C(CCc1nc(-c2ccc(O)cn2)no1)NC1=C(C(=O)O)CC(c2ccc(F)nc2)CC1 CHEMBL1084031 IC50 9.0 nM
O=C(CCc1nc(-c2ccc(F)cn2)no1)NC1=C(C(=O)O)CC(c2cc(F)cc(F)c2F)CC1 CHEMBL1083442 IC50 9.0 nM
CCCC1CCC(C(=O)O)=C(NC(=O)C(C)Cc2ccn(-c3ccc(O)cn3)n2)C1 CHEMBL1082823 IC50 9.0 nM
O=C(CCC#Cc1ccc(O)cc1Cl)NC1=C(C(=O)O)CCCC1 CHEMBL4082765 EC50 9.0 nM
O=C(CCc1nc(-c2ccc(O)cc2)no1)Nc1ccccc1C(=O)O CHEMBL391813 IC50 10.0 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)NC1=C(C(=O)O)CCCC1 CHEMBL1084059 IC50 10.0 nM
O=c1[nH]c(=O)c2c(CCCC(F)(F)F)cc(=O)oc2[nH]1 CHEMBL2036952 EC50 10.0 nM
O=c1[nH]c(=O)c2c(CCCCC3CC3)cc(=O)oc2[nH]1 CHEMBL2036957 EC50 10.0 nM
COc1ccc(-c2cc3cc(C4Nc5ccccc5C(=O)N4C)cc(C)c3oc2=O)cc1 CHEMBL4164140 pEC50 10.59 nM
O=C(CCc1cn2c(n1)sc1cc(O)ccc12)Nc1ccccc1C(=O)O CHEMBL484783 IC50 11.0 nM
O=C(O)C1=C(NC(=O)C2(Cc3nc(-c4ccc(O)cn4)no3)CC2)CCCC1 CHEMBL1086658 Ki 11.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2ccccc2F)CC1 CHEMBL1085653 IC50 11.0 nM
C[C@@H]1CCC(C(=O)O)=C(NC(=O)[C@@H](N)Cc2nc(-c3ccc(O)cn3)no2)C1 CHEMBL1770356 IC50 11.0 nM
CSCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036828 EC50 11.0 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)NC1=C(C(=O)O)CCC(c2cccc(F)c2)C1 CHEMBL1082824 IC50 12.0 nM
C[C@@H]1CCC(C(=O)O)=C(NC(=O)[C@@H](N)Cc2nc(-c3ccc(F)cn3)no2)C1 CHEMBL1770358 IC50 12.0 nM
O=C(O)c1n[nH]c2c1C[C@H]1C[C@@H]21 CHEMBL2057618 EC50 12.9 nM
O=C(CCc1cnn2c1CCc1cc(O)ccc1-2)Nc1ccccc1C(=O)O CHEMBL482768 IC50 13.0 nM
O=C(CCc1noc2c1CCc1cc(O)ccc1-2)NC1=C(C(=O)O)CCC1 CHEMBL485326 IC50 13.0 nM
O=C(CCc1cc2n(n1)-c1ccc(O)cc1CC2)Nc1ccccc1C(=O)O CHEMBL1770173 IC50 13.0 nM
O=c1[nH]c(=O)c2c(CCC3CC3)cc(=O)oc2[nH]1 CHEMBL2036953 EC50 13.0 nM
O=C(CCC#Cc1ccc(O)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4063682 IC50 13.0 nM
Cn1nccc1C1CCC(NC(=O)CCc2ccc3cc(O)ccc3c2)=C(C(=O)O)C1 CHEMBL1086029 IC50 14.0 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)NC1=C(C(=O)O)CC[C@@H](C)C1 CHEMBL1084332 IC50 14.0 nM
O=C(O)c1n[nH]c2c1CC1C2C12CCCC2 CHEMBL2057610 EC50 14.0 nM
NC(Cc1nc(-c2ccc(F)cn2)no1)C(=O)NC1=C(C(=O)O)CC(c2cc(F)cc(F)c2F)CC1 CHEMBL1082294 IC50 15.0 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)NC1=C(C(=O)O)CCC(c2cc(F)c(F)c(F)c2)C1 CHEMBL1085842 IC50 15.0 nM
Cc1c(CCC(=O)Nc2ccccc2C(=O)O)cnn1-c1ccc(O)cn1 CHEMBL1086108 IC50 15.0 nM
O=c1[nH]c(OCCCOc2ccccc2Cl)nc2ncccc12 CHEMBL1224070 IC50 15.0 nM
O=C(CCc1ccc2c(Cl)c(O)ccc2c1)Nc1ccccc1C(=O)O CHEMBL4647392 EC50 15.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2ccc(F)nc2)CC1 CHEMBL1083450 IC50 16.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2)cc1)Nc1ccccc1C(=O)O CHEMBL1085711 IC50 16.0 nM
CCC1(CCCc2cc(=O)oc3[nH]c(=O)[nH]c(=O)c23)CC1 CHEMBL2036959 EC50 16.0 nM
O=c1[nH]c(=O)c2c(CCCC3(F)CC3)cc(=O)oc2[nH]1 CHEMBL2035002 EC50 16.0 nM
O=C(/C=C/C#Cc1ccccc1F)NC1=C(C(=O)O)CCCC1 CHEMBL4073322 IC50 16.0 nM
C[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057614 EC50 16.4 nM
O=C(CCc1[nH]nc2c1CCc1cc(O)ccc1-2)Nc1ccccc1C(=O)O CHEMBL520136 IC50 17.0 nM
CCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036813 EC50 17.0 nM
O=C(CCc1ccc2c(ccc3[nH]ncc32)c1)Nc1ccccc1C(=O)O CHEMBL485185 IC50 18.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2ccc(C(F)(F)F)nc2)CC1 CHEMBL1083451 IC50 18.0 nM
O=C(CCc1nc(-c2ccc(F)cn2)no1)NC1=C(C(=O)O)CC(c2cc(F)cc(F)c2)CC1 CHEMBL1084841 IC50 19.0 nM
O=C(CCc1ccc(-c2ccccc2Cl)cc1)Nc1ccccc1C(=O)O CHEMBL1083473 IC50 19.0 nM
CCCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036825 EC50 19.0 nM
O=C(CCc1cnc(-n2cc(O)cn2)s1)Nc1ccccc1C(=O)O CHEMBL237036 IC50 20.0 nM
O=C(O)c1n[nH]c2c1CC(c1cc(F)cc(F)c1F)C2 CHEMBL1208923 IC50 20.0 nM
CC1CCC(NC(=O)[C@@H](N)Cc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)C1 CHEMBL1770357 IC50 20.0 nM
CCCCn1cc(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)c(C(=O)O)c1 CHEMBL4648435 IC50 20.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)Nc1ccccc1C(=O)O CHEMBL522649 IC50 21.0 nM
C[C@@H]1CCC(C(=O)O)=C(NC(=O)CCc2nc(-c3ccc(F)cn3)no2)C1 CHEMBL1770359 IC50 21.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL3589836 IC50 21.0 nM
O=C(O)C1=C(NC(=O)C(O)Cc2nc(-c3ccc(O)cn3)no2)CCCC1 CHEMBL1088213 Ki 22.0 nM
CC(Cc1cnn(-c2ccc(O)cn2)c1)C(=O)NC1=C(C(=O)O)CCCC1 CHEMBL1084448 IC50 22.0 nM
CCC#CCOc1nc2oc(=O)cc(CCC3CCC3)c2c(=O)[nH]1 CHEMBL1939047 EC50 22.0 nM
CC[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057619 EC50 22.5 nM
O=C(CCc1cn2c(n1)sc1cc(O)ccc12)NC1=C(C(=O)O)CCC1 CHEMBL485327 IC50 23.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2F)cc1)Nc1ccccc1C(=O)O CHEMBL3589834 IC50 23.0 nM
Cc1c(CCC(=O)Nc2ccccc2C(=O)O)cnn1-c1ccc(O)cc1 CHEMBL236163 IC50 24.0 nM
Cc1cc(C(=O)O)n[nH]1 CHEMBL391574 Log EC50 24.55 nM
CC(Cc1ccn(-c2ccc(O)cn2)n1)C(=O)Nc1ccccc1C(=O)O CHEMBL1085875 IC50 25.0 nM
O=C(/C=C/C#Cc1ccc(O)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4065654 IC50 25.0 nM
O=C(CCc1cnc(-c2ccc(O)cn2)s1)Nc1ccccc1C(=O)O CHEMBL237037 IC50 26.0 nM
O=C(CCc1cnn(-c2ccc(O)cn2)c1)NC1=C(C(=O)O)CCCC1 CHEMBL1085150 IC50 26.0 nM
Cc1c(CC(C)C(=O)NC2=C(C(=O)O)CCCC2)cnn1-c1ccc(O)cc1 CHEMBL1085402 IC50 26.0 nM
CCc1cc(=O)oc2nc(OCC#CCCCO)[nH]c(=O)c12 CHEMBL1939043 EC50 26.0 nM
O=c1[nH]c(=O)c2c(CCCc3cccs3)cc(=O)oc2[nH]1 CHEMBL2036823 EC50 26.0 nM
O=C(O)c1n[nH]c2c1CC1CC21 CHEMBL2059221 EC50 27.5 nM
NC(Cc1nc(-c2ccc(F)cn2)no1)C(=O)NC1=C(C(=O)O)CC(c2cc(F)cc(F)c2)CC1 CHEMBL1083743 IC50 28.0 nM
CCCCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036826 EC50 28.0 nM
C=CC[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2059827 EC50 28.0 nM
O=C(CCC#Cc1ccc(O)cc1F)NC1=C(C(=O)O)CCCC1 CHEMBL4060899 IC50 28.0 nM
CC(CC(=O)NC1=C(C(=O)O)CCCC1)c1nc(-c2ccc(O)cn2)no1 CHEMBL1084393 Ki 29.0 nM
Cc1ccc(-c2cc3cc(C4Nc5ccccc5C(=O)N4C)cc(C)c3oc2=O)cc1 CHEMBL4174798 pEC50 30.48 nM
O=C(CCc1cn2c(n1)sc1ccccc12)Nc1ccccc1C(=O)O CHEMBL520620 IC50 31.0 nM
CCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036810 EC50 31.0 nM
NC(Cc1nc(-c2ccc(F)cn2)no1)C(=O)NC1=C(C(=O)O)CCCC1 CHEMBL1085816 IC50 32.0 nM
O=C(CCc1cnn(-c2ccc(O)cc2)c1)Nc1ccccc1C(=O)O CHEMBL1086103 IC50 32.0 nM
O=C(CCc1ccc(-c2cccc(O)c2)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4083762 IC50 32.0 nM
O=c1[nH]c(OCCCOc2cccc(Cl)c2)nc2ncccc12 CHEMBL1224071 IC50 33.0 nM
Nc1ccc2cc(CCC(=O)Nc3ccccc3C(=O)O)ccc2c1 CHEMBL491002 IC50 34.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2ccccc2)CC1 CHEMBL1086355 IC50 34.0 nM
CCc1cc(=O)oc2nc(OCC#CC3CC3)[nH]c(=O)c12 CHEMBL1939039 EC50 34.0 nM
Cn1nc2c(c1CCC(=O)Nc1ccccc1C(=O)O)CCc1cc(O)ccc1-2 CHEMBL482963 IC50 35.0 nM
O=C(CCc1nc(-c2ccc(F)cn2)no1)NC1=C(C(=O)O)CCCC1 CHEMBL1085815 IC50 35.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2)cc1)NC1=C(C(=O)O)CC(c2cccnc2F)CC1 CHEMBL1086031 IC50 36.0 nM
O=C(CCC#Cc1ccccc1F)NC1=C(C(=O)O)CCCC1 CHEMBL4072283 EC50 36.0 nM
O=C(/C=C/C#Cc1ccccc1O)NC1=C(C(=O)O)CCCC1 CHEMBL4069406 IC50 37.0 nM
CCOc1cc(Cl)c(-c2ccc(-c3nc4ccc(S(=O)(=O)C5CCN(C)CC5)cc4s3)c(=O)[nH]2)cc1N1CCOCC1 CHEMBL4642043 EC50 37.0 nM
O=c1[nH]c(=O)c2c(CCCC3CCC3)cc(=O)oc2[nH]1 CHEMBL2036956 EC50 39.0 nM
Fc1cc(F)c(F)c(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 CHEMBL520137 IC50 40.0 nM
O=C(CCc1ccc(-c2ccccc2O)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4076822 IC50 40.0 nM
N[C@H](Cc1nc(-c2ccc(O)cc2)no1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770176 IC50 41.0 nM
Cc1[nH]nc(C(=O)O)c1F CHEMBL238004 Log EC50 41.69 nM
N[C@@H](Cc1nc(-c2ccc(O)cc2)no1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770175 IC50 42.0 nM
CC1CCC(NC(=O)CCc2ccc3cc(O)ccc3c2)=C(C(=O)O)C1 CHEMBL1083174 IC50 43.0 nM
C1c2c(-c3nnn[nH]3)n[nH]c2[C@H]2C[C@@H]12 CHEMBL1085289 EC50 45.0 nM
Cc1c(CC(C)C(=O)NC2=C(C(=O)O)CCCC2)cnn1-c1ccc(O)cn1 CHEMBL1085149 IC50 46.0 nM
O=c1[nH]c(=O)c2c(CCc3cccs3)cc(=O)oc2[nH]1 CHEMBL2036824 EC50 47.0 nM
CC1(c2csc(Br)c2)OC(C(=O)O)=CC1=O CHEMBL375493 EC50 48.0 nM
CC1(CCCc2cc(=O)oc3nc(C(F)F)[nH]c(=O)c23)CC1 CHEMBL1672639 EC50 49.0 nM
O=c1[nH]c(COCCc2cccc(Cl)c2)nc2ncccc12 CHEMBL1224219 IC50 50.0 nM
O=C(CCc1ncc(-c2ccc(O)cn2)s1)Nc1ccccc1C(=O)O CHEMBL237247 IC50 51.0 nM
CCCCn1cc(NC(=O)CCc2ccc3c(Cl)c(O)ccc3c2)c(C(=O)O)c1 CHEMBL4632359 IC50 51.0 nM
CCCCc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12 CHEMBL5270112 EC50 51.0 nM
O=c1cc(CCCCCl)c2c(=O)[nH]c(=S)[nH]c2o1 CHEMBL5275861 EC50 51.0 nM
O=c1[nH]c(=O)c2c(CCCCCl)cc(=O)oc2[nH]1 CHEMBL5284951 EC50 51.0 nM
Cc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12 CHEMBL5281556 EC50 51.0 nM
CCc1cc(=O)oc2nc(S)[nH]c(=O)c12 CHEMBL1672755 EC50 51.0 nM
CCCc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12 CHEMBL5277000 EC50 51.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(c2cccnc2F)CC1 CHEMBL1083139 IC50 52.0 nM
CCCC#CCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939038 EC50 53.0 nM
O=Cc1ccc2cc(CCC(=O)Nc3ccccc3C(=O)O)ccc2c1 CHEMBL491003 IC50 55.0 nM
O=C(CCC#Cc1ccccc1Cl)NC1=C(C(=O)O)CCCC1 CHEMBL4099238 IC50 56.0 nM
O=C(CCc1nc(-c2ccc(F)cn2)no1)NC1=C(C(=O)O)CC(c2cccc(F)c2)CC1 CHEMBL1084839 IC50 57.0 nM
CCc1[nH]nc(C(=O)O)c1F CHEMBL396864 Log EC50 57.54 nM
O=C(CCc1ccn(-c2ccc(O)cn2)n1)Nc1ccccc1C(=O)O CHEMBL237543 IC50 58.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2O)cc1)Nc1ccccc1C(=O)O CHEMBL3589835 IC50 58.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2F)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4064786 IC50 58.0 nM
O=c1cc(CCCC2CC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1671877 EC50 59.0 nM
CCc1noc(C)c1COc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939032 EC50 63.0 nM
CC1(c2csc(Cl)c2)OC(C(=O)O)=CC1=O CHEMBL221282 EC50 66.0 nM
CCC#CCOc1nc2oc(=O)cc(CCC(C)C)c2c(=O)[nH]1 CHEMBL1939045 EC50 66.0 nM
O=C(O)c1n[nH]c2c1CC(c1cc(F)cc(F)c1F)CC2 CHEMBL558463 IC50 67.0 nM
CCC#CCOc1nc2oc(=O)cc(CCCC3CC3)c2c(=O)[nH]1 CHEMBL1939049 EC50 67.0 nM
Fc1cc(F)cc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 CHEMBL507182 IC50 70.0 nM
CCCCCc1cc(C(=O)O)[nH]n1 CHEMBL247921 Ki 72.0 nM
O=C(CCc1ccc(-c2ccccc2Cl)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4073374 IC50 75.0 nM
Cc1c(CC(C)C(=O)Nc2ccccc2C(=O)O)cnn1-c1ccc(O)cc1 CHEMBL1086104 IC50 77.0 nM
CCCCc1[nH]nc(C(=O)O)c1F CHEMBL235009 Log EC50 79.43 nM
CCc1cc(C(=O)O)[nH]n1 CHEMBL394498 Log EC50 79.43 nM
CCCCC1Cc2[nH]nc(-c3nnn[nH]3)c2C1 CHEMBL509541 IC50 80.0 nM
CC(C)C[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2059821 EC50 81.0 nM
CSC[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057605 EC50 83.0 nM
O=C(CCc1ccc(-c2ccccc2F)cc1)Nc1ccccc1C(=O)O CHEMBL3589788 IC50 83.0 nM
NC(Cc1nc(-c2ccc(F)cn2)no1)C(=O)NC1=C(C(=O)O)CC(c2cccc(F)c2)CC1 CHEMBL1084840 IC50 85.0 nM
CCCCc1cc(C(=O)O)n[nH]1 CHEMBL428730 Log EC50 85.11 nM
O=C(CCc1ccc(-c2ccccc2O)cc1)Nc1ccccc1C(=O)O CHEMBL3589790 IC50 86.0 nM
COc1ccc2cc(CCC(=O)Nc3ccccc3C(=O)O)ccc2c1 CHEMBL492220 IC50 87.0 nM
O=C(/C=C/C#Cc1ccccc1Cl)NC1=C(C(=O)O)CCCC1 CHEMBL4093294 IC50 88.0 nM
O=C(O)c1n[nH]c2c1CC(c1cc(F)ccc1F)CC2 CHEMBL1237148 IC50 90.0 nM
O=C(O)c1n[nH]c2c1CC(c1ccsc1)C2 CHEMBL1208925 IC50 90.0 nM
CCC#CCOc1nc2oc(=O)cc(CCC3CC3)c2c(=O)[nH]1 CHEMBL1939048 EC50 90.0 nM
Cc1c(CC(C)C(=O)Nc2ccccc2C(=O)O)cnn1-c1ccc(O)cn1 CHEMBL1085401 IC50 91.0 nM
O=C(CCc1ccc(-c2ccc(O)c(F)c2)cc1)Nc1ccccc1C(=O)O CHEMBL3589793 IC50 91.0 nM
CCc1cc(=O)oc2nc(OCc3ccnnc3)[nH]c(=O)c12 CHEMBL1939031 EC50 93.0 nM
O=C(CCc1ccc(-c2ccccc2)cc1)Nc1ccccc1C(=O)O CHEMBL235741 IC50 94.0 nM
CCC#CCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939037 EC50 96.0 nM
CCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036812 EC50 99.0 nM
O=C(O)c1cc(C2CC2)n[nH]1 CHEMBL247098 Log EC50 100.0 nM
NC(Cc1cnc(-c2ccc(O)cc2Cl)s1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770172 IC50 100.0 nM
CC(c1nc(-c2ccc(O)cn2)no1)[C@H](N)C(=O)Nc1ccccc1C(=O)O CHEMBL1770354 IC50 100.0 nM
O=C(CCc1ccc(-c2ccc(O)cc2)cc1)Nc1sccc1C(=O)O CHEMBL3589837 IC50 105.0 nM
O=c1cc(CCC2CCC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672732 EC50 108.0 nM
N[C@H](CC(=O)Nc1ccccc1C(=O)O)c1nc(-c2ccc(O)cc2)no1 CHEMBL1770177 IC50 108.0 nM
CC(C)c1cc(C(=O)O)n[nH]1 CHEMBL238002 Log EC50 109.65 nM
COCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036827 EC50 110.0 nM
O=C(/C=C/C#Cc1ccc(O)cc1F)NC1=C(C(=O)O)CCCC1 CHEMBL4093990 EC50 110.0 nM
CCc1cc(=O)oc2nc(OCc3ccccc3OC)[nH]c(=O)c12 CHEMBL1939021 EC50 113.0 nM
CN[C@@H](Cc1nc(-c2ccc(O)cc2)no1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770179 IC50 115.0 nM
O=C(CCc1ccc(-c2ccccn2)cc1)Nc1ccccc1C(=O)O CHEMBL391603 IC50 120.0 nM
Cc1c(C(=O)N[C@H](C)COc2ccccc2)cnc2c(-c3ccc(C(C)C)cc3)cnn12 CHEMBL490599 EC50 120.0 nM
Cn1cc(C2CCC(NC(=O)CCc3ccc4cc(O)ccc4c3)=C(C(=O)O)C2)cn1 CHEMBL1086030 IC50 120.0 nM
NC(Cc1cc2n(n1)-c1ccc(O)cc1CC2)C(=O)Nc1ccccc1C(=O)O CHEMBL1770174 IC50 120.0 nM
O=C(O)c1cc(NCc2ccccc2)[nH]n1 CHEMBL553435 pEC50 120.23 nM
CCOc1cc(Cl)c(C(=O)NC(=O)Nc2nc3ccc(S(=O)(=O)C4CCN(C)CC4)cc3s2)cc1-n1cccn1 CHEMBL4641579 EC50 123.0 nM
CCc1cc(=O)oc2nc(OC)[nH]c(=O)c12 CHEMBL1939011 EC50 125.0 nM
CCCCCc1cc(=O)oc2nc(C(F)F)[nH]c(=O)c12 CHEMBL1672751 EC50 128.0 nM
Cc1cc(O)ccc1-c1ccc(CCC(=O)Nc2ccccc2C(=O)O)cc1 CHEMBL3589833 IC50 129.0 nM
Cn1nc(CCC(=O)Nc2ccccc2C(=O)O)c2c1-c1ccc(O)cc1CC2 CHEMBL483160 IC50 130.0 nM
CC(C)(CC(=O)NC1=C(C(=O)O)CCCC1)c1nc(-c2ccc(O)cn2)no1 CHEMBL1084394 Ki 130.0 nM
O=c1[nH]c(OCCCOc2ccccc2)nc2ncccc12 CHEMBL1223957 IC50 130.0 nM
O=c1cc(CCC2CC3(CC3)C2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672738 EC50 130.0 nM
COC(=O)/C=C/C(=O)OC CHEMBL2107333 IC50 130.0 nM
CCc1cc(=O)oc2nc(OCc3ccccc3C(F)(F)F)[nH]c(=O)c12 CHEMBL1939024 EC50 133.0 nM
CCC#CCOc1nc2oc(=O)cc(Cc3ccccc3)c2c(=O)[nH]1 CHEMBL1939044 EC50 137.0 nM
CCc1cc(=O)oc2nc(OCCOC)[nH]c(=O)c12 CHEMBL1939016 EC50 138.0 nM
O=C(CCC#Cc1cccc(O)c1)NC1=C(C(=O)O)CCCC1 CHEMBL4091501 IC50 138.0 nM
O=C(CCc1ccc2ccccc2c1)Nc1ccccc1C(=O)O CHEMBL235740 IC50 140.0 nM
O=C(O)c1ccccc1NC(=O)N1CCN(c2cnc3cc(O)ccc3n2)CC1 CHEMBL398496 IC50 140.0 nM
Fc1cccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1F CHEMBL520676 IC50 140.0 nM
Fc1cccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 CHEMBL519966 IC50 140.0 nM
COC[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057603 EC50 141.0 nM
Fc1ccc(F)c(C2CCc3[nH]nc(-c4nnn[nH]4)c3C2)c1 CHEMBL565163 IC50 150.0 nM
Fc1ncccc1C1CCC2=C(C1)C(=C1N=NN=N1)N=N2 CHEMBL1204125 IC50 150.0 nM
N[C@@H](Cc1ccc(-c2ccc(O)cc2)cc1)C(=O)Nc1ccccc1C(=O)O CHEMBL1770171 IC50 150.0 nM
O=C(O)c1n[nH]c2c1CCC2 CHEMBL128604 Ki 156.0 nM
C=C[C@@H]1[C@H]2Cc3c(-c4nnn[nH]4)n[nH]c3[C@@H]12 CHEMBL1085534 EC50 156.0 nM
N[C@@H](CC(=O)Nc1ccccc1C(=O)O)c1nc(-c2ccc(O)cc2)no1 CHEMBL1770178 IC50 158.0 nM
CC1(c2ccccc2)OC(C(=O)O)=CC1=O CHEMBL278488 EC50 160.0 nM
O=c1[nH]c(=O)c2c(Cc3ccc(F)cc3)cc(=O)oc2[nH]1 CHEMBL2036820 EC50 170.0 nM
CCC#CCOc1nc2oc(=O)cc(CCC3CCCC3)c2c(=O)[nH]1 CHEMBL1939046 EC50 172.0 nM
CCc1cc(=O)oc2nc(OCC#CC3CCCCC3)[nH]c(=O)c12 CHEMBL1939040 EC50 177.0 nM
CCc1cc(=O)oc2nc(OCC#CCCO)[nH]c(=O)c12 CHEMBL1939042 EC50 179.0 nM
CCCc1cc(C(=O)O)n[nH]1 CHEMBL237788 Log EC50 181.97 nM
CCc1cc(=O)oc2nc(OCc3ccccc3)[nH]c(=O)c12 CHEMBL1939014 EC50 190.0 nM
O=C(CCc1ccc(-c2ccccc2F)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4100231 EC50 190.0 nM
CCOC[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057607 EC50 192.0 nM
O=C(O)c1n[nH]c2c1CC(c1cccnc1F)CC2 CHEMBL1237147 IC50 200.0 nM
O=C(O)c1n[nH]c2c1CC(c1ccccc1)C2 CHEMBL1208922 IC50 200.0 nM
Cc1cc(-c2ccc(CCC(=O)Nc3ccccc3C(=O)O)cc2)ccc1O CHEMBL3589791 IC50 201.0 nM
C1c2c(-c3nnn[nH]3)n[nH]c2C2CC12 CHEMBL1169573 EC50 210.0 nM
O=C(O)c1n[nH]c2c1CC(c1cc(F)ccc1F)CC2 CHEMBL542000 IC50 220.0 nM
O=c1[nH]c(COCCc2ccccc2F)nc2ncccc12 CHEMBL1224146 IC50 220.0 nM
CC(C)c1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036814 EC50 220.0 nM
CCn1cc(NC(=O)CCc2nc(-c3ccc(O)cc3)no2)c(C(=O)O)c1 CHEMBL4636989 IC50 220.0 nM
CCCC[C@@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2059224 EC50 225.0 nM
C=CC[C@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2059828 EC50 227.0 nM
O=C(CCC#Cc1ccccc1O)NC1=C(C(=O)O)CCCC1 CHEMBL4101720 IC50 229.0 nM
O=c1[nH]c(OCCCOc2ccc(Cl)cc2)nc2ncccc12 CHEMBL1224072 IC50 230.0 nM
O=c1[nH]c(COCCc2cccc(F)c2)nc2ncccc12 CHEMBL1221438 IC50 230.0 nM
CCCC(C)c1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036830 EC50 230.0 nM
CCCCn1cc(C(=O)O)c(NC(=O)CCc2ccc3c(Cl)c(O)ccc3c2)n1 CHEMBL4643451 IC50 230.0 nM
CCc1cc(=O)oc2nc(OCc3ccccc3-c3cccc(C#N)c3)[nH]c(=O)c12 CHEMBL1939027 EC50 238.0 nM
Cc1cc(C2(C)OC(C(=O)O)=CC2=O)cs1 CHEMBL424938 EC50 240.0 nM
O=C(O)c1n[nH]c2c1CC(c1cccs1)C2 CHEMBL1208924 IC50 240.0 nM
C[C@@H]1[C@H]2Cc3c(-c4nnn[nH]4)n[nH]c3[C@@H]12 CHEMBL1084950 EC50 244.0 nM
CCCCc1cc(=O)oc2nc(C(F)F)[nH]c(=O)c12 CHEMBL1672750 EC50 245.0 nM
O=c1[nH]c(OCCCOc2ccccc2F)nc2ncccc12 CHEMBL1223959 IC50 250.0 nM
O=C(CCc1cnn(-c2ccccc2)c1)Nc1ccccc1C(=O)O CHEMBL1086568 IC50 260.0 nM
COc1nc2oc(=O)cc(CCC(C)C)c2c(=O)[nH]1 CHEMBL1939020 EC50 260.0 nM
O=C(O)c1n[nH]c(C2CC2)c1F CHEMBL392859 Log EC50 269.15 nM
O=C(O)c1n[nH]c2c1CC(c1ccccc1F)CC2 CHEMBL562632 IC50 270.0 nM
CCc1cc(=O)oc2nc(OCc3ccc(C(F)(F)F)cc3)[nH]c(=O)c12 CHEMBL1939026 EC50 270.0 nM
CC(C)CCc1cc(=O)oc2nc(C(F)F)[nH]c(=O)c12 CHEMBL1672753 EC50 275.0 nM
CCc1cc(C2Nc3ccccc3C(=O)N2C)cc2cc(-c3ccc4c(c3)OCO4)c(=O)oc12 CHEMBL4163051 pEC50 275.42 nM
C/C=C/[C@@H]1[C@H]2Cc3c(-c4nnn[nH]4)n[nH]c3[C@@H]12 CHEMBL1085537 EC50 276.0 nM
CC[C@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057620 EC50 276.0 nM
O=C(CCc1nc(-c2ccc(F)cn2)no1)NC1=C(C(=O)O)CC(c2ccc(F)nc2)CC1 CHEMBL1084798 IC50 280.0 nM
O=c1cc(CCCC2(F)CC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672645 EC50 281.0 nM
O=C(CCc1ccc(-c2cccc(F)c2)cc1)Nc1ccccc1C(=O)O CHEMBL3589785 IC50 283.0 nM
CCc1cc(=O)oc2nc(OCC3CC3)[nH]c(=O)c12 CHEMBL1939013 EC50 285.0 nM
C1Cc2[nH]nc(-c3nn[nH]n3)c2C1 CHEMBL456145 EC50 286.0 nM
CC1(c2cccc(Br)c2)OC(C(=O)O)=CC1=O CHEMBL219980 EC50 290.0 nM
COc1cccc2nc(N3CCN(C(=O)Nc4ccccc4C(=O)O)CC3)cnc12 CHEMBL252708 IC50 290.0 nM
Clc1cccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 CHEMBL502716 IC50 290.0 nM
CCc1cc(=O)oc2nc(OCc3cccc(C(F)(F)F)c3)[nH]c(=O)c12 CHEMBL1939025 EC50 290.0 nM
Cc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036811 EC50 290.0 nM
CCc1cc(=O)oc2nc(OCc3ccc(-c4cncnc4)cc3F)[nH]c(=O)c12 CHEMBL1939029 EC50 291.0 nM
O=C(CCC#Cc1ccc(F)cc1)NC1=C(C(=O)O)CCCC1 CHEMBL4091542 IC50 291.0 nM
CCCCCCc1cc(=O)oc2nc(C(F)F)[nH]c(=O)c12 CHEMBL1672752 EC50 308.0 nM
O=C(CCc1ccn(-c2ccccc2)n1)Nc1ccccc1C(=O)O CHEMBL1086567 IC50 310.0 nM
CCC(C)Cc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036947 EC50 310.0 nM
C[C@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057615 EC50 311.0 nM
CCc1cc(=O)oc2nc(OCC#CCO)[nH]c(=O)c12 CHEMBL1939041 EC50 312.0 nM
COc1nc2oc(=O)cc(CCC3CCCC3)c2c(=O)[nH]1 CHEMBL1939019 EC50 319.0 nM
O=C(CCc1ccc(-c2ccc(F)cc2)cc1)Nc1ccccc1C(=O)O CHEMBL3589779 IC50 323.0 nM
O=C(CCc1ccc(-c2ccccc2C(F)(F)F)cc1)Nc1ccccc1C(=O)O CHEMBL3589789 IC50 326.0 nM
CCC1(CCCc2cc(=O)oc3nc(C(F)F)[nH]c(=O)c23)CC1 CHEMBL1672640 EC50 327.0 nM
O=C(/C=C/C#Cc1ccccc1)NC1=C(C(=O)O)CCCC1 CHEMBL3299113 IC50 327.0 nM
O=C(CCc1nnc(-c2ccc(O)cc2)o1)Nc1ccccc1C(=O)O CHEMBL236164 IC50 330.0 nM
CCc1cc(=O)oc2nc(CF)[nH]c(=O)c12 CHEMBL1672744 EC50 335.0 nM
Cn1c(=O)c2cc(O)ccc2c2ccc(CCC(=O)Nc3ccccc3C(=O)O)cc21 CHEMBL485184 IC50 340.0 nM
O=C(CCc1ccc(-c2ccc[nH]2)cc1)Nc1ccccc1C(=O)O CHEMBL428724 IC50 350.0 nM
CCc1cc(=O)oc2nc(C(F)F)[nH]c(=O)c12 CHEMBL1672743 EC50 353.0 nM
Cn1c(=O)c2c(CCC(=O)Nc3ccccc3C(=O)O)nnn2c2ccc(O)cc21 CHEMBL484605 IC50 360.0 nM
O=C(O)C1=C(NC(=O)C2(Cc3nc(-c4ccc(O)cn4)no3)CCC2)CCCC1 CHEMBL1088074 Ki 360.0 nM
O=C(CCc1ccc(-c2ccc(O)c(Cl)c2)cc1)Nc1ccccc1C(=O)O CHEMBL3589792 IC50 365.0 nM
O=c1[nH]c(OC/C=C/c2ccccc2)nc2ncccc12 CHEMBL1223956 IC50 370.0 nM
O=c1[nH]c(OCCCOc2cccc(F)c2)nc2ncccc12 CHEMBL1223960 IC50 370.0 nM
CC1CC(CCc2cc(=O)oc3nc(C(F)F)[nH]c(=O)c23)C1 CHEMBL1672737 EC50 379.0 nM
O=C(CCc1noc2c1Cc1cc(O)ccc1-2)Nc1ccccc1C(=O)O CHEMBL482980 IC50 380.0 nM
CCCC1Cc2[nH]nc(C(=O)O)c2C1 CHEMBL1208919 IC50 380.0 nM
O=C(COc1ccc2cc(O)ccc2c1)Nc1ccccc1C(=O)O CHEMBL1802361 EC50 380.0 nM
O=C(/C=C/C#Cc1cccc(O)c1)NC1=C(C(=O)O)CCCC1 CHEMBL4096635 IC50 383.0 nM
Cn1nccc1C1Cc2[nH]nc(C(=O)O)c2C1 CHEMBL1208986 IC50 390.0 nM
CC(C)n1nnc2cc(C(=O)O)ccc21 CHEMBL381638 EC50 400.0 nM
Fc1ccccc1C1Cc2[nH]nc(-c3nnn[nH]3)c2C1 CHEMBL504980 IC50 410.0 nM
Cc1cccc(CCOCc2nc3ncccc3c(=O)[nH]2)c1 CHEMBL1224222 IC50 410.0 nM
CCOC(=O)/C=C/C(=O)O CHEMBL1771637 Ki 410.0 nM
CCCCN1CC(C(=O)O)=C(NC(=O)CCc2ccc3c(Cl)c(O)ccc3c2)C1=O CHEMBL4643073 IC50 410.0 nM
CCCCc1cc(=O)oc2nc(OC)[nH]c(=O)c12 CHEMBL1939018 EC50 417.0 nM
O=C(CCc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CC(O)CC1 CHEMBL1086356 IC50 420.0 nM
CC#CCCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939050 EC50 424.0 nM
CC#CCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939036 EC50 425.0 nM
CC1(c2cccc(I)c2)OC(C(=O)O)=CC1=O CHEMBL223013 EC50 430.0 nM
c1ccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)cc1 CHEMBL520675 IC50 430.0 nM
Cc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1 CHEMBL1224221 IC50 440.0 nM
Cc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1 CHEMBL1224073 IC50 450.0 nM
O=c1cc(CCC2CC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672733 EC50 451.0 nM
Cc1cc(C2Nc3ccccc3C(=O)N2C)cc2cc(-c3ccc4c(c3)OCO4)c(=O)oc12 CHEMBL4159670 EC50 454.0 nM
Cc1c(C(=O)NCCOc2ccc(F)cc2)cnc2c(-c3ccc(C(C)C)cc3)cnn12 CHEMBL522281 EC50 460.0 nM
O=C(O)c1n[nH]c2c1CC(c1ccccc1Cl)CC2 CHEMBL560406 IC50 460.0 nM
CCCCn1cc(NC(=O)CCc2ccc3c(Cl)c(O)ccc3c2)c(C(=O)O)n1 CHEMBL4641756 IC50 460.0 nM
CS(=O)(=O)CCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036829 EC50 470.0 nM
O=c1cc(CCCC2CCC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672736 EC50 479.0 nM
Cc1ccc(C2(C)OC(C(=O)O)=CC2=O)s1 CHEMBL223566 EC50 480.0 nM
Cc1ncc(C(=O)O)s1 CHEMBL247134 EC50 500.0 nM
Fc1ncccc1C1CCc2[nH]nc(-c3nnn[nH]3)c2C1 CHEMBL558334 IC50 500.0 nM
CC[C@@H]1[C@H]2Cc3c(-c4nnn[nH]4)n[nH]c3[C@@H]12 CHEMBL1083682 EC50 504.0 nM
C1CC1[C@@H]1[C@H]2Cc3c(-c4nnn[nH]4)n[nH]c3[C@H]21 CHEMBL1085535 EC50 507.0 nM
CCC[C@@H]1[C@H]2Cc3c(-c4nnn[nH]4)n[nH]c3[C@@H]12 CHEMBL1085536 EC50 541.0 nM
O=C(O)c1ccccc1NC(=O)N1CCN(c2cnc3ccccc3n2)CC1 CHEMBL252306 IC50 550.0 nM
Cn1cc(NC(=O)CCc2nc(-c3ccc(O)cc3)no2)c(C(=O)O)c1 CHEMBL4639053 IC50 550.0 nM
Cc1ccccc1-c1ccc(CCC(=O)Nc2ccccc2C(=O)O)cc1 CHEMBL3589787 IC50 555.0 nM
CCc1noc(CC)c1COc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939033 EC50 588.0 nM
O=c1cc(CCCCC2CC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672741 EC50 591.0 nM
O=C(O)c1n[nH]c2c1CC(c1cccnc1F)CC2 CHEMBL539398 IC50 600.0 nM
O=c1[nH]c(COCCc2ccccc2Cl)nc2ncccc12 CHEMBL1224218 IC50 600.0 nM
Fc1ccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)cc1F CHEMBL519811 IC50 610.0 nM
CCOc1cc(Cl)c(-c2ccc(-c3nc4ccccc4s3)c(=O)[nH]2)cc1N1CCOCC1 CHEMBL4649089 EC50 610.0 nM
O=C(CCc1nc(-c2ccc(O)cc2)no1)Nc1cn(Cc2ccccc2)cc1C(=O)O CHEMBL4647670 IC50 620.0 nM
O=c1[nH]c(COCCc2ccc(F)cc2)nc2ncccc12 CHEMBL1224147 IC50 630.0 nM
C[C@@H]1CN(c2cnc3ccccc3n2)[C@@H](C)CN1C(=O)Nc1ccccc1C(=O)O CHEMBL251222 IC50 650.0 nM
CCOc1cc(Cl)c(C(=O)Nc2nc3ccc(S(=O)(=O)CCCN4CCN(C)CC4)cc3s2)cc1N1C[C@@H](C)O[C@@H](C)C1 CHEMBL4636832 EC50 660.0 nM
O=C(CCC#Cc1ccc(O)cn1)NC1=C(C(=O)O)CCCC1 CHEMBL4099278 IC50 665.0 nM
O=c1[nH]c(COCCc2ccccc2)nc2ncccc12 CHEMBL1223878 IC50 670.0 nM
CCCC1Cc2[nH]nc(-c3nnn[nH]3)c2C1 CHEMBL500239 IC50 690.0 nM
Cc1c(C(=O)NC(C)COc2ccccc2)cnc2c(-c3ccc(C(C)C)cc3)cnn12 CHEMBL492020 EC50 700.0 nM
CCCCCOC(=O)/C=C/C(=O)O CHEMBL1771641 Ki 700.0 nM
CCc1cc(=O)oc2nc(OCc3cccc(-c4cccc(C#N)c4)c3)[nH]c(=O)c12 CHEMBL1939028 EC50 723.0 nM
CCc1cc(=O)oc2nc(OCc3cccnc3)[nH]c(=O)c12 CHEMBL1939030 EC50 738.0 nM
CC1(c2cc(Br)cs2)OC(C(=O)O)=CC1=O CHEMBL222472 EC50 740.0 nM
O=C(CCc1nc(-c2ccc(O)cn2)no1)Nc1cn(CCCF)cc1C(=O)O CHEMBL4647933 IC50 740.0 nM
CCc1[nH]nc(-c2nnn[nH]2)c1F CHEMBL397055 Log EC50 758.58 nM
Fc1ccc(F)c(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 CHEMBL483142 IC50 760.0 nM
CCCCOC(=O)/C=C/C(=O)O CHEMBL1771640 Ki 760.0 nM
COc1cccc(-c2ccc(CCC(=O)Nc3ccccc3C(=O)O)cc2)c1 CHEMBL3589783 IC50 769.0 nM
O=C(O)c1cc[nH]n1 CHEMBL128679 Log EC50 776.25 nM
CC(C)C1(CCCc2cc(=O)oc3nc(C(F)F)[nH]c(=O)c23)CC1 CHEMBL1672641 EC50 787.0 nM
O=C(O)c1ccccc1NC(=O)N1CCN(c2cnc3ccc(O)cc3n2)CC1 CHEMBL253128 IC50 790.0 nM
O=C(O)c1ccccc1NC(=O)N1CCCN(c2cnc3ccccc3n2)CC1 CHEMBL248851 IC50 800.0 nM
Cc1cccc(-c2ccc(CCC(=O)Nc3ccccc3C(=O)O)cc2)c1 CHEMBL3589782 IC50 800.0 nM
O=c1cc(CC2CCC2)c2c(=O)[nH]c(C(F)F)nc2o1 CHEMBL1672735 EC50 821.0 nM
O=c1[nH]c(OCCCCc2ccccc2)nc2ncccc12 CHEMBL1223877 IC50 840.0 nM
CSC[C@H]1[C@@H]2Cc3c(C(=O)O)n[nH]c3[C@H]12 CHEMBL2057606 EC50 857.0 nM
Cc1cccc(OCCCOc2nc3ncccc3c(=O)[nH]2)c1 CHEMBL1224074 IC50 860.0 nM
CCc1cc(=O)oc2nc(OCc3cccc(OC)c3)[nH]c(=O)c12 CHEMBL1939022 EC50 860.0 nM
O=C(O)c1ccccc1NC(=O)N1CCN(c2cnc3cccc(O)c3n2)CC1 CHEMBL399859 IC50 870.0 nM
CCCCCCC1Cc2[nH]nc(-c3nnn[nH]3)c2C1 CHEMBL484172 IC50 870.0 nM
O=C(C#Cc1ccc2cc(O)ccc2c1)NC1=C(C(=O)O)CCCC1 CHEMBL3298702 EC50 900.0 nM
CCOc1cc(Cl)c(-c2ccc(-c3nc4c(s3)CN(C(=O)CO)CC4)c(=O)[nH]2)cc1N1CCOCC1 CHEMBL4635089 EC50 910.0 nM
C#CCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 CHEMBL1939035 EC50 911.0 nM
O=C(CCc1ccccc1)NCc1nc2ncccc2c(=O)[nH]1 CHEMBL1223958 IC50 920.0 nM
COc1cccc(OCCNC(=O)c2cnc3c(-c4ccc(C(C)C)cc4)cnn3c2C)c1 CHEMBL491227 EC50 930.0 nM
CCOC(=O)Cc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 CHEMBL2036819 EC50 930.0 nM
O=C(CCc1ccc(-c2cccc(O)c2)cc1)Nc1ccccc1C(=O)O CHEMBL3589786 IC50 940.0 nM
Cn1cc(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)c(C(=O)O)c1 CHEMBL4633857 IC50 970.0 nM
Cc1c(C(=O)NCCOc2ccccc2)cnc2c(-c3ccc(C(C)C)cc3)cnn12 CHEMBL490216 IC50 1000.0 nM
O=C(CCCCc1ccc2ccccc2c1)Nc1ccccc1C(=O)O CHEMBL483153 EC50 1000.0 nM
CCCOC(=O)/C=C/C(=O)O CHEMBL1771638 Ki 1000.0 nM