CN(C)CCN(C)c1ccc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)cnc2c1 CHEMBL4860757 IC50 0.0 nM
CN(C)CCNc1ccc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)ncc2c1 CHEMBL4856052 IC50 0.0 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL343448 Ki 0.0015 nM
O=C(CCCCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621294 IC50 0.00687 nM
CCC(CC)CN(CC)Cc1c(C)nc2cc(/C=C/C(=O)NO)ccn12 CHEMBL3689858 IC50 0.01 nM
CCCCNCc1c(CCCC)nc2cc(/C=C/C(=O)NO)ccn12 CHEMBL3689829 IC50 0.02 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 Ki 0.03 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL430060 Ki 0.04 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3cccnc3cc2OC)[nH]1 CHEMBL4861467 IC50 0.05 nM
COc1ccc(Nc2c(NC(C)(C)CCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4250302 Ki 0.056 nM
Cc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4239232 Ki 0.057 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccn2c1CN(CC)CCCC CHEMBL3689834 IC50 0.06 nM
COc1ccc(Nc2c(NC3(CCCCC(=O)NO)CCC3)c(=O)c2=O)cc1 CHEMBL4237636 Ki 0.063 nM
COc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4237803 Ki 0.075 nM
CN1CC(C(=O)N[C@@H](CCCCCC(=O)c2ccon2)c2ncc(-c3ccccc3F)[nH]2)C1 CHEMBL4641682 IC50 0.08 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4649205 IC50 0.085 nM
Cc1ccc(Nc2c(NC(C)CCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4251203 Ki 0.097 nM
O=C1N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@@H]2C(=O)N[C@@H](CCCCCC(=O)[C@@H]2CO2)C(=O)N[C@H]1Cc1ccccc1 CHEMBL2000089 IC50 0.11 nM
O=C1C[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)N1 CHEMBL4568666 IC50 0.11 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644038 IC50 0.11 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCOCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4876610 IC50 0.11 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(c(OC)cc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4878197 IC50 0.11 nM
C/C=C1\NC(=O)[C@@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL146250 IC50 0.12 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 IC50 0.15 nM
C[C@H](CCCCC(=O)NO)Nc1c(Nc2ccc3cc(C(F)(F)F)[nH]c3c2)c(=O)c1=O CHEMBL4246561 Ki 0.15 nM
CC1(C)NC[C@H](CCCCCC(=O)C2CO2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL4438063 IC50 0.15 nM
Cc1cc(C(=O)CCCCC[C@H](NC(=O)C2CN(C)C2)c2ncc(-c3ccccc3F)[nH]2)no1 CHEMBL4637689 IC50 0.16 nM
Cn1cc(-c2ccc(S(=O)(=O)n3ccc(/C=C/C(=O)Nc4ccccc4N)c3)cc2)cn1 CHEMBL4283683 IC50 0.16 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)o1 CHEMBL4862152 IC50 0.17 nM
C[C@@H]1CN(C(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cnn(CCCCCCC(=O)NO)c4n3)cc2)CCO1 CHEMBL4532398 IC50 0.19 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4642518 IC50 0.19 nM
O=C(NCCS)/C(Cc1cc(Br)c(O)c(Br)c1)=N/O CHEMBL2047701 IC50 0.2 nM
CSCC[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](C(C)C)[C@@H](O)CC(=O)O2 CHEMBL3126833 IC50 0.2 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1c[nH]cn1)NC2=O CHEMBL3317812 IC50 0.2 nM
CN1CC(C(=O)N[C@@H](CCCCCC(=O)c2ccon2)c2ncc(-c3ccccc3F)o2)C1 CHEMBL4634501 IC50 0.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(-c3cccnc3)cc2)nc1C#N CHEMBL4746782 IC50 0.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3[nH]c4ccccc4c3c2)[nH]1 CHEMBL4780309 IC50 0.2 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL27759 IC50 0.2 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4860000 IC50 0.2 nM
[11CH3]n1cc(CCNCc2ccc(/C=C/C(=O)NO)cc2)c2ccccc21 CHEMBL5288006 IC50 0.2 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1ccc(O)cc1)NC2=O CHEMBL3317811 IC50 0.21 nM
Nc1ccc(-c2nc(N3CCOCC3)c3cnn(CCCCCCC(=O)NO)c3n2)cc1 CHEMBL4552057 IC50 0.21 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637357 IC50 0.22 nM
O=C(CCCCCNc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O)NO CHEMBL4241807 Ki 0.23 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCC(N(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4642023 IC50 0.24 nM
Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cnnn2CCCCCC(=O)NO)c1 CHEMBL2408778 Ki 0.26 nM
Cc1cc2ccc(Nc3c(NCCCCCC(=O)NO)c(=O)c3=O)cc2[nH]1 CHEMBL4247370 Ki 0.27 nM
COc1ccc(Nc2c(NC(C)CCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4250739 Ki 0.27 nM
CC(C)(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4241370 Ki 0.27 nM
CC[C@H](C)[C@H]1NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](CCSC)C(=O)N2)OC(=O)C[C@@H]1O CHEMBL1836142 IC50 0.28 nM
CC(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4240635 Ki 0.28 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3ccncc3)cc2)[nH]1 CHEMBL5218926 IC50 0.28 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1ccccc1)NC2=O CHEMBL3317810 IC50 0.29 nM
O=C(CCCCCNc1c(Nc2ccccc2)c(=O)c1=O)NO CHEMBL4251365 Ki 0.29 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638264 IC50 0.29 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCC/C=C/[C@@H]2CC(=O)NCc3nc(cs3)C3=N[C@@](C)(CS3)C(=O)N[C@@H](C(C)C)C(=O)O2)OC1=O CHEMBL3329621 IC50 0.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc3nc(C)ccc3c2)nc1C#N CHEMBL4759693 IC50 0.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(N4CCCC4)ccc3c2)[nH]1 CHEMBL5220616 IC50 0.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)cc2)[nH]1 CHEMBL5219739 IC50 0.31 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(N4CCCC4)nc3cc2OC)[nH]1 CHEMBL4861271 IC50 0.32 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(CC)ccc3c2)[nH]1 CHEMBL5219006 IC50 0.32 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCCN2C1=O CHEMBL5413269 Ki 0.32 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCOCCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4869000 IC50 0.33 nM
Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5433552 IC50 0.34 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)o1 CHEMBL5220278 IC50 0.35 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 0.36 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nn(C)cc3c2)[nH]1 CHEMBL5219969 IC50 0.38 nM
Cc1cccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)c1 CHEMBL4248374 Ki 0.39 nM
CC1(C)NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL360194 IC50 0.4 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OC)cc2)NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCN2C1=O CHEMBL2158745 IC50 0.4 nM
CC(C)[C@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL1796689 IC50 0.4 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)OC1=O CHEMBL3329622 IC50 0.4 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593247 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc3nn(C)cc3c2)nc1C#N CHEMBL4761973 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4785376 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3ccccc3c2)[nH]1 CHEMBL4745088 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(OC)ccc3c2)[nH]1 CHEMBL5219634 IC50 0.4 nM
Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)c(F)c2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5395502 IC50 0.43 nM
C[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)NC(=O)[C@@H](C)NC1=O CHEMBL279636 Ki 0.44 nM
COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3828518 IC50 0.45 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccncc3nc2OC)o1 CHEMBL5219490 IC50 0.45 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C(\F)CCS)OC1=O CHEMBL4441774 IC50 0.46 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1cccnc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4639206 IC50 0.46 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL3039527 IC50 0.46 nM
CSc1ccc(C/C(=N\O)C(=O)NCCS)cc1Br CHEMBL2047694 IC50 0.48 nM
CCCC[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](C(C)C)[C@@H](O)CC(=O)O2 CHEMBL3218562 IC50 0.48 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(-c3ccccc3)[nH]c2=O)[nH]1 CHEMBL5219338 IC50 0.48 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cccnc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828636 IC50 0.49 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3ccc(F)c(O)c3)nc21)NO CHEMBL4787120 IC50 0.49 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccc(=O)n(C)c3cc2OC)o1 CHEMBL5220454 IC50 0.49 nM
COc1cc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)ccc1N(C)C CHEMBL4244350 Ki 0.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cn(C)c3ccccc23)[nH]1 CHEMBL4742026 IC50 0.5 nM
Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 IC50 0.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(-c4ncco4)ccc3c2)[nH]1 CHEMBL5219359 IC50 0.5 nM
CCC(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4249385 Ki 0.51 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)NCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4094507 IC50 0.53 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3ncccc3c2)[nH]1 CHEMBL5218535 IC50 0.53 nM
CC(C)[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)O2 CHEMBL4746359 IC50 0.54 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 Ki 0.55 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccncc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827517 IC50 0.55 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cccc(O)c3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828492 IC50 0.55 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cnccn3)cc2)[nH]1 CHEMBL5219422 IC50 0.55 nM
O=C(CCCCCCNc1c(Nc2ccccc2)c(=O)c1=O)NO CHEMBL4245007 Ki 0.56 nM
C[C@H](CCCCC(=O)NO)Nc1c(Nc2ccc(OC(F)(F)F)cc2)c(=O)c1=O CHEMBL4242292 Ki 0.58 nM
O=C(NO)c1cnc(N2CCC3(CCN(Cc4c[nH]c5ccccc45)C3)CC2)nc1 CHEMBL4763061 IC50 0.58 nM
CC(C)=CCC/C(C)=C\CC/C(C)=C\CSc1ccccc1C(=O)NCCCCC(=O)NO CHEMBL5220511 IC50 0.58 nM
COc1cc(C/C(=N\O)C(=O)NCCS)ccc1SC CHEMBL2047702 IC50 0.6 nM
COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 CHEMBL3759059 IC50 0.6 nM
Cc1nn2ccccc2c1CCN1CCCC1c1ccc(/C=C/C(=O)NO)cc1 CHEMBL4455057 IC50 0.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4748244 IC50 0.6 nM
O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)NO CHEMBL99392 Ki 0.6 nM
NC(=O)c1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cc1 CHEMBL4798716 IC50 0.61 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCOCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4853593 IC50 0.61 nM
Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cn(CCCCCC(=O)NO)nn2)c1 CHEMBL2408777 Ki 0.62 nM
CC(C)(C)OC(=O)n1cnc(C[C@@H]2NC(=O)[C@]3(C)CSC(=N3)c3csc(n3)CNC(=O)C[C@@H](/C=C/CCS)OC2=O)c1 CHEMBL3317818 IC50 0.62 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827814 IC50 0.65 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(O)cc3)c2)cc1 CHEMBL5403602 IC50 0.66 nM
CC(CCCCC(=O)NO)Nc1c(Nc2ccccc2)c(=O)c1=O CHEMBL4246919 Ki 0.69 nM
Nc1ncc(-c2nc(N3CCC(O)CC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4748726 IC50 0.69 nM
O=C(CCCCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3759921 IC50 0.7 nM
O=C(CCCCCCn1cc(-c2ccc3ncnc(Nc4cccc(Cl)c4F)c3c2)nn1)NO CHEMBL3930620 IC50 0.72 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc4ccccc4c3)CCOCC2)cc1 CHEMBL4642874 IC50 0.72 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638330 IC50 0.72 nM
CC(C)[C@H]1NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)C[C@@H]1O CHEMBL2313363 IC50 0.75 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3cccc(OCCO)c3)nc21)NO CHEMBL4753381 IC50 0.76 nM
CN(Cc1c(C(C)(C)C)nc2cc(/C=C/C(=O)NO)ccn12)CC(C)(C)C CHEMBL4472220 IC50 0.78 nM
CC(=O)Nc1cccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)c1 CHEMBL4742983 IC50 0.78 nM
Nc1nc2cc(-c3nn(CCCCCCC(=O)NO)c4ncnc(N)c34)ccc2o1 CHEMBL4846560 IC50 0.78 nM
COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(=O)NO)C(=O)NCCc3c(-c4ccccc4)[nH]c4ccccc34)c2c1 CHEMBL216641 IC50 0.8 nM
CCc1n[nH]c(CC)c1CCN1CCCC1c1ccc(/C=C/C(=O)NO)cc1 CHEMBL4543166 IC50 0.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1C[C@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644118 IC50 0.8 nM
CN(C)c1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3827296 IC50 0.81 nM
Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cnnn2CCCCCCC(=O)NO)c1 CHEMBL2408779 Ki 0.82 nM
O=C1C[C@H]2CCCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)N1 CHEMBL4571133 IC50 0.82 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4069404 IC50 0.84 nM
NC(=O)c1cccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)c1 CHEMBL4740827 IC50 0.84 nM
CC(=O)Nc1ccc(C(=O)Nc2ccccc2N)cc1 CHEMBL235191 K 0.84 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 Ki 0.85 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(S(C)(=O)=O)cc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827865 IC50 0.85 nM
Nc1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4785064 IC50 0.85 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 IC50 0.85 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3310505 Ki 0.88 nM
COc1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cc1CO CHEMBL4760754 IC50 0.89 nM
O=C(CCCCCCOc1ccc2ccccc2c1)NO CHEMBL217083 IC50 0.9 nM
O=C(NCCS)/C(Cc1ccc(O)c(Br)c1)=N/O CHEMBL2047540 IC50 0.9 nM
O=C(/C=C/c1ccc(C2CCCN2CCc2cnn3ccccc23)cc1)NO CHEMBL4574244 IC50 0.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4648704 IC50 0.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(Cl)ccc2OC)[nH]1 CHEMBL4753452 IC50 0.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(-n4cccn4)ccc3c2)[nH]1 CHEMBL5220720 IC50 0.9 nM
CN(C)c1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4242426 Ki 0.91 nM
Nc1nc2cc(-c3nn(CC4CCN(c5ncc(C(=O)NO)cn5)CC4)c4ncnc(N)c34)ccc2o1 CHEMBL4862549 IC50 0.91 nM
O=C(/C=C/c1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2cccc(Br)c2)cc1)NO CHEMBL4592929 IC50 0.9177 nM
CCC(=O)CCCCC[C@H](NC(=O)C1=NOC2(CCN(C)CC2)C1)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4633758 IC50 0.92 nM
CC[C@H](C)[C@H]1NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](CC[S+](C)[O-])C(=O)N2)OC(=O)C[C@@H]1O CHEMBL1835659 IC50 0.93 nM
CSCC[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](CC(C)C)[C@@H](O)CC(=O)O2 CHEMBL3218563 IC50 0.94 nM
CC(=O)Nc1ccccc1-c1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCC2)cc1 CHEMBL4632569 IC50 0.94 nM
CC(C)(C)OC(=O)NCCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3317817 IC50 0.96 nM
CC(C)C[C@H]1NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)CNC1=O CHEMBL4777615 IC50 0.96 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc4c(c3)OCO4)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828180 IC50 0.97 nM
Nc1ncc(-c2nc(N3CCC(CO)CC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4764799 IC50 0.99 nM
O=C(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)NO CHEMBL327146 IC50 1.0 nM
O=C(/C=C/c1cccc(C(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)c1)NO CHEMBL116620 IC50 1.0 nM
O=C(CCCCCC(=O)N(CC(=O)Nc1ccc2[nH]ncc2c1)CC(=O)Nc1ccc2[nH]ncc2c1)NO CHEMBL409847 IC50 1.0 nM
Cc1nn2ccccc2c1CCN(Cc1ccc(/C=C/C(=O)NO)cc1)C(C)C CHEMBL1819273 IC50 1.0 nM
CCc1nn2ccccc2c1CCN(Cc1ccc(/C=C/C(=O)NO)cc1)C(C)C CHEMBL1819274 IC50 1.0 nM
COc1ccc(C/C(=N\O)C(=O)NCCS)cc1I CHEMBL2047691 IC50 1.0 nM
O=C(NCCS)/C(Cc1ccc(F)c(Br)c1)=N/O CHEMBL2047692 IC50 1.0 nM
COc1cc(C/C(=N\O)C(=O)NCCS)cc(I)c1OC CHEMBL2047695 IC50 1.0 nM
COc1cc(C/C(=N\O)C(=O)NCCS)cc(Br)c1OC CHEMBL2047696 IC50 1.0 nM
O=C(NCCS)/C(Cc1cccc([N+](=O)[O-])c1)=N/O CHEMBL2047699 IC50 1.0 nM
CN(C)c1ccc(C/C(=N\O)C(=O)NCCS)cc1 CHEMBL2047703 IC50 1.0 nM
CCn1c(CN(C)c2ncc(C(=O)NO)cn2)nc2c(N3CCOCC3)nc(-c3ccc(OC)cc3)nc21 CHEMBL3827738 IC50 1.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cn1 CHEMBL3827281 IC50 1.0 nM
CC(=O)Nc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL235842 IC50 1.0 nM
Cc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3827650 IC50 1.0 nM
O=C(/C=C/c1ccc(C2CCCN2CCc2c(-c3cccnc3)nn3ccccc23)cc1)NO CHEMBL4454463 IC50 1.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CC2(C1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4641343 IC50 1.0 nM
CCC(=O)CCCCC[C@H](NC(=O)CC1CC2(C1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638976 IC50 1.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C)ccc2OC)[nH]1 CHEMBL4792257 IC50 1.0 nM
CCC(=O)CCCCC[C@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL4873847 IC50 1.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc2c(c1)ncn2CCN1CCOCC1 CHEMBL4853232 IC50 1.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2c(c1)CC(=O)N2CCCN1CCOCC1 CHEMBL4856764 IC50 1.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2c(c1)CC(=O)N2CCN1CCOCC1 CHEMBL4848938 IC50 1.0 nM
Nc1nn(-c2ccc3ncccc3c2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5394047 IC50 1.0 nM
Nc1ccc(-n2cc(-c3cccc(NC(=O)CCCCCCC(=O)NO)c3)nn2)cc1 CHEMBL1094708 IC50 1.01 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(Cl)c(C(F)(F)F)c3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828408 IC50 1.01 nM
COc1cc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc(OC)c1OC CHEMBL3827794 IC50 1.02 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827894 IC50 1.04 nM
Cc1[nH]c2ccccc2c1CCNCc1cccc(/C=C/C(=O)NO)c1 CHEMBL4080164 IC50 1.06 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cccnc2)cc1)NO CHEMBL3759794 IC50 1.1 nM
CCNc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3826997 IC50 1.1 nM
CN(Cc1nc2c(N3CCOCC3)nc(Cl)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828747 IC50 1.1 nM
CCOC(=O)c1cc2cc(OC)c(-c3cnc([C@H](CCCCCC(=O)CC)NC(=O)[C@H]4CC45CCN(CC)CC5)[nH]3)cc2o1 CHEMBL4758559 IC50 1.1 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21)NO CHEMBL4749655 IC50 1.1 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL443392 IC50 1.1 nM
O=C(CCCCCCn1cc(-c2ccc3ncnc(Nc4ccc(Br)cc4F)c3c2)nn1)NO CHEMBL4863294 IC50 1.1 nM
O=C(CCCCCCN1CC(c2ccc3ncnc(Nc4ccc(Br)cc4F)c3c2)N=N1)NO CHEMBL5178922 IC50 1.1 nM
O=C(CCCCn1cc(-c2ccc3ncnc(Nc4ccccc4F)c3c2)nn1)NO CHEMBL5201054 IC50 1.1 nM
O=C(CCCCCn1cc(-c2ccc3ncnc(Nc4ccc(Br)cc4F)c3c2)nn1)NO CHEMBL5280359 IC50 1.1 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(N)nc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827660 IC50 1.11 nM
Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1C CHEMBL3339026 IC50 1.14 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cncnc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827004 IC50 1.14 nM
O=C(CCCCCC(=O)N(Cc1ccc(Br)s1)c1ccc(OCCN2CCOCC2)cc1)NO CHEMBL5274330 IC50 1.14 nM
O=C(CCCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2ccccc21)NO CHEMBL5208269 IC50 1.16 nM
COc1ccc2c(c1)cc(C(=O)NC1C3CC4CC(C3)CC1C4)n2CCCCCCC(=O)NO CHEMBL5175796 IC50 1.16 nM
CCCC[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H]([C@@H](C)CC)[C@@H](O)CC(=O)O2 CHEMBL1836145 IC50 1.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1C[C@@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4634829 IC50 1.2 nM
CS(=O)(=O)Nc1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cc1 CHEMBL4779376 IC50 1.2 nM
O=C(CCCCc1nnc(-c2cc3c([nH]c4ccccc43)c(-c3ccccc3)n2)o1)NO CHEMBL5173197 IC50 1.2 nM
CC(C)[C@H](N)C(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL5314582 IC50 1.2 nM
O=C(CCCCCCNc1cc(N2CCCCCC2)nc(-c2cccnc2)n1)NO CHEMBL5415711 IC50 1.2 nM
CCCNNC(=O)/C=C/c1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL4444219 IC50 1.23 nM
O=C(/C=C/c1ccc(S(=O)(=O)NCCc2cccc3[nH]ccc23)cc1)NO CHEMBL4069853 IC50 1.28 nM
O=C(CCCCC[C@H](NC(=O)c1ccccn1)C(=O)Nc1ccc2ncccc2c1)NO CHEMBL393060 IC50 1.3 nM
COc1ccncc1-c1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819257 IC50 1.3 nM
O=C(/C=C/C#Cc1ccc(NS(=O)(=O)c2ccccc2)cc1)NO CHEMBL314389 Ki 1.3 nM
COc1ncc(-c2cc(OCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cc1F CHEMBL4474676 IC50 1.3 nM
COc1ccc(-c2cc(OCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cn1 CHEMBL4462577 IC50 1.3 nM
COc1ncc(-c2cc(OCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1NS(C)(=O)=O CHEMBL4456391 IC50 1.3 nM
COc1ccc(-c2cc(OCCCCCCC(=O)NO)c3ncnc(C)c3c2)cn1 CHEMBL4561458 IC50 1.3 nM
COc1cc(-c2nc(NCc3cccc(/C=C/C(=O)NO)c3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL4461441 IC50 1.3 nM
COc1ncc(-c2cc(OCCN(C)c3ncc(C(=O)NO)cn3)c3nc(N)nc(C)c3c2)cc1C CHEMBL5182515 IC50 1.3 nM
COc1cc2nc(NCCCCCC(=O)NO)nc(NC3CCN(C)CC3)c2cc1OC CHEMBL5182385 IC50 1.3 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCCCCCC(=O)NO)c4)nc3c2)c1 CHEMBL5177696 IC50 1.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(ccc(=O)n3C)c2)[nH]1 CHEMBL5218980 IC50 1.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2F)o1 CHEMBL5220408 IC50 1.3 nM
Nc1nn(-c2ccc3ccccc3c2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5414898 IC50 1.3 nM
O=C(CCCCCCn1cc(C(=O)NC2CCCCCCC2)c2ccccc21)NO CHEMBL5185898 IC50 1.31 nM
Cn1ccc2c(CCNS(=O)(=O)c3ccc(/C=C/C(=O)NO)cc3)cccc21 CHEMBL4065026 IC50 1.34 nM
CCn1c(CN(C)c2ncc(C(=O)NO)cn2)nc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21 CHEMBL3827612 IC50 1.37 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3759982 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)C12CCN(CC1)CC2)c1ncc(-c2ccc3ccccc3c2)[nH]1 CHEMBL3809599 IC50 1.4 nM
O=C(CCCCCn1cc(-c2ccc3ncnc(Nc4cccc(Cl)c4F)c3c2)nn1)NO CHEMBL3929484 IC50 1.4 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)NCCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4068308 IC50 1.4 nM
O=C(CCCCCNc1c(NC2CCCCC2)c(=O)c1=O)NO CHEMBL4242750 Ki 1.4 nM
COc1ncc(-c2cc(OCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1F CHEMBL4536105 IC50 1.4 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1ncc(-c2ccccc2F)[nH]1 CHEMBL4644307 IC50 1.4 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3ccc4cn[nH]c4c3)nc21)NO CHEMBL4742243 IC50 1.4 nM
COc1ncc(-c2cc(OCCCCCCC(=O)NO)c3nc(N)nc(C)c3c2)cc1F CHEMBL5194391 IC50 1.4 nM
O=C(CCCCCCC(=O)Nc1nc2c(s1)C[C@@H](NC(=O)c1cccc3ccccc13)CC2)NO CHEMBL5199007 IC50 1.4 nM
COc1cc(-c2nc(-c3nnc(CCCCC(=O)NO)o3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL5192364 IC50 1.4 nM
O=C(CN1CCc2c(oc3cc4c(cc23)OCO4)C1)Nc1ccc(C(=O)NO)cc1 CHEMBL5421202 IC50 1.4 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 Ki 1.5 nM
CC(C)(C)c1[nH]c2ncccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819267 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4646915 IC50 1.5 nM
Nc1ncc(-c2nc(N3CCOCC3)c3ccn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4744689 IC50 1.5 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3[nH]2)cc1 CHEMBL5083249 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2Cl)[nH]1 CHEMBL5218651 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2ccc3ccccc3c2)[nH]1 CHEMBL5285293 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3cccnc3cc2OC)o1 CHEMBL4862556 IC50 1.52 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(N4CCOCC4)cc3)c2)cc1 CHEMBL5433364 IC50 1.53 nM
O=C(CCCCCCn1cc(C(=O)NC2CCCCC2)c2ccccc21)NO CHEMBL5197455 IC50 1.56 nM
COc1ccc(C(F)(F)F)cc1-c1nc(N2CCOCC2)c2nc(CN(C)c3ncc(C(=O)NO)cn3)n(C)c2n1 CHEMBL3828289 IC50 1.59 nM
CC(C)[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](C(C)C)C(=O)NCC(=O)O2 CHEMBL235082 IC50 1.6 nM
CC(C)[C@H]1NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C)C(=O)N2)OC(=O)CNC1=O CHEMBL393360 IC50 1.6 nM
O=C(C=C1c2ccccc2-c2ccccc21)NCCCCCC(=O)NO CHEMBL485514 IC50 1.6 nM
CCn1c(CN(C)c2ncc(C(=O)NO)cn2)nc2c(N3CCOCC3)nc(-c3ccc(OC)nc3)nc21 CHEMBL3827317 IC50 1.6 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cnc4ccccc4c3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828628 IC50 1.6 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)NCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4083345 IC50 1.6 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)NCCCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4102249 IC50 1.6 nM
C/C=C1\NC(=O)[C@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL4061025 IC50 1.6 nM
COc1ccc(-c2cc(OCCN(c3ncc(C(=O)NO)cn3)C(C)C)c3ncnc(C)c3c2)cn1 CHEMBL4521497 IC50 1.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4636652 IC50 1.6 nM
O=C(CCCCCCn1ccc2c(N3CCOCC3)nc(-c3cccc(O)c3)nc21)NO CHEMBL4796562 IC50 1.6 nM
Cc1[nH]c2ccccc2c1C1=CCC(NCc2ccc(OCC(=O)NO)cc2F)CC1 CHEMBL5185310 IC50 1.6 nM
CCC(=O)CCCCC[C@H](NC(=O)C12CCN(CC1)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5282110 IC50 1.6 nM
CN1CCN(c2ccc(-c3cc(C(=O)NCc4ccc(C(=O)NO)cc4)ccn3)cc2)CC1 CHEMBL5437604 IC50 1.61 nM
O=C(CCCCCCn1c(C(=O)NC2C3CC4CC(C3)CC2C4)nc2ccccc21)NO CHEMBL5191345 IC50 1.68 nM
COc1ncc(-c2cc(OCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL4444204 IC50 1.7 nM
COc1ccc(-c2cc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3c2)cn1 CHEMBL4648157 IC50 1.7 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3cn[nH]c3)nc21)NO CHEMBL4776660 IC50 1.7 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ccc(C(=O)NO)cc4)cc3n2)cn1 CHEMBL5278968 IC50 1.7 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5271471 IC50 1.7 nM
C#Cc1ccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL5432435 IC50 1.7 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2cc3ccccc3[nH]2)cc1)NO CHEMBL403323 IC50 1.8 nM
COc1ccc(C/C(=N\O)C(=O)NCCS)cc1Br CHEMBL2047541 IC50 1.8 nM
COc1cc2ncnc(Nc3ccc(Br)cc3)c2cc1OCCCCCCC(=O)NO CHEMBL3759186 IC50 1.8 nM
COc1ncc(-c2cc(OCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL4581165 IC50 1.8 nM
COc1cccc(-c2nc(NCc3ccc(/C=C/C(=O)NO)cc3)cc3c2[nH]c2ccccc23)c1 CHEMBL4456371 IC50 1.8 nM
Cc1ccc(CN2CCC(c3noc(CN(C)c4ncc(C(=O)NO)cn4)n3)CC2)cc1 CHEMBL4517151 IC50 1.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C(F)(F)F)ccc2OC)[nH]1 CHEMBL4747553 IC50 1.8 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccccc3F)ccc12)NO CHEMBL4786031 IC50 1.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C4CC4)nc3cc2F)o1 CHEMBL5219978 IC50 1.8 nM
COc1ccc(-c2cc(-c3ccn(Cc4ccc(C(=O)NO)cc4)n3)ccn2)cc1 CHEMBL5434546 IC50 1.88 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccccc3)ncnc2s1)NO CHEMBL3339022 IC50 1.9 nM
O=C(CCCCC(Cc1ccccc1)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O)NO CHEMBL4238353 Ki 1.9 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCCCNC(=O)O[C@@H]1CC/C=C/CCC1)NC2=O CHEMBL4291290 IC50 1.9 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1[nH]c(-c2ccccc2)nc1C(N)=O CHEMBL4776685 IC50 1.9 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4790137 IC50 1.9 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(OCCN4CCOCC4)cc3)c2)cc1 CHEMBL5429412 IC50 1.9 nM
O=C(CN1CCc2c(oc3cc(O)ccc23)C1)Nc1ccc(C(=O)NO)cc1 CHEMBL5427151 IC50 1.9 nM
COc1ccc2c3c(oc2c1)CN([C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccc(C(=O)NO)cc1)CC3 CHEMBL5413391 IC50 1.9 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(N4CCOCC4)c(Cl)c3)c2)cc1 CHEMBL5406191 IC50 1.91 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)NC1=O CHEMBL3593407 IC50 1.95 nM
CCc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3827780 IC50 1.98 nM
O=C(CCCCCCC(=O)c1ccc(-c2ccc(Br)cc2)cc1)NO CHEMBL99456 IC50 2.0 nM
CN(Cc1ccc(Cl)cc1)c1ccc(OCCCCCCC(=O)NO)cc1 CHEMBL217154 IC50 2.0 nM
C[C@@H]1NC(=O)C2(Cc3ccccc3C2)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C1=O CHEMBL394261 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCN(C)CC1)c1ncc(-c2ccc3ncccc3c2)[nH]1 CHEMBL2448566 IC50 2.0 nM
CC(C)C[C@H]1CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCCC(=O)NO)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1 CHEMBL585939 IC50 2.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 Ki 2.0 nM
CC(C)(C)c1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819260 IC50 2.0 nM
O=C(/C=C/c1ccc(CNCCc2c(-c3ccccc3)nn3ccccc23)cc1)NO CHEMBL1819272 IC50 2.0 nM
O=C(CCNC(=O)/C(Cc1ccc(O)c(Br)c1)=N/O)NO CHEMBL2047684 IC50 2.0 nM
CSc1ccc(C/C(=N\O)C(=O)NCCS)cc1 CHEMBL2047690 IC50 2.0 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL3098602 IC50 2.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356916 IC50 2.0 nM
CC(C)CCN(CCCCCCC(=O)NO)c1ncc(C(=O)NCCCn2ccnc2)s1 CHEMBL4170617 IC50 2.0 nM
O=C(CCCCCCC(=O)Nc1ccc(Nc2nc(-c3cn[nH]c3)c3cc[nH]c3n2)cc1)NO CHEMBL4243347 IC50 2.0 nM
COc1ncc(-c2cc(OCCN(c3ncc(C(=O)NO)cn3)C(C)C)c3ncnc(C)c3c2)cc1F CHEMBL4464542 IC50 2.0 nM
O=C(O)c1cccc(-c2ccc(C3(C(=O)Nc4ccc(C(=O)NO)cc4)CCCC3)cc2)c1 CHEMBL4640415 IC50 2.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cn[nH]c4)cc3)CCOCC2)cc1 CHEMBL4640304 IC50 2.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cn[nH]c4)cc3)CCCCC2)cc1 CHEMBL4639966 IC50 2.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(Br)cc3)CCOCC2)cc1 CHEMBL4634521 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4646582 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1ccccc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644387 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)ccc2OC)[nH]1 CHEMBL4759606 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL2448576 IC50 2.0 nM
CCCC[C@H](NC(=O)[C@H](CN)c1c(C)[nH]c2ccc(O)cc12)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4867665 IC50 2.0 nM
COc1cc2nc(C3CCCCC3)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4845706 IC50 2.0 nM
O=C(CCCCCCn1cc(C(=O)NC2CCCCCC2)c2ccccc21)NO CHEMBL5174843 IC50 2.0 nM
CC(=O)Nc1ccc(C(=O)Nc2cc(-c3ccncc3)ccc2N)cc1 CHEMBL5440469 IC50 2.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL253868 IC50 2.0 nM
Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1 CHEMBL3339024 IC50 2.01 nM
O=C(CCCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c2ccccc21)NO CHEMBL5206239 IC50 2.04 nM
COc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)cc1 CHEMBL5435925 IC50 2.07 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cccs2)cc1)NO CHEMBL3758735 IC50 2.1 nM
CCN(CCOc1cc(-c2ccc(OC)nc2)cc2c(C)ncnc12)c1ncc(C(=O)NO)cn1 CHEMBL4588397 IC50 2.1 nM
COc1ncc(-c2cc(OCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1NS(C)(=O)=O CHEMBL4535819 IC50 2.1 nM
CC(C)[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](C)C(=O)NCC(=O)O2 CHEMBL4798082 IC50 2.1 nM
CCOc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4776328 IC50 2.1 nM
O=C(COc1ccc(CNCCc2c[nH]c3ccccc23)c(F)c1)NO CHEMBL5185297 IC50 2.1 nM
O=C(CCCCCCn1c(C(=O)NC2C3CC4CC(C3)CC2C4)cc2ccccc21)NO CHEMBL5169341 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3[nH]c2=O)o1 CHEMBL5279520 IC50 2.1 nM
COc1ccc2c3c(oc2c1)CN([C@@H](CCSC)C(=O)Nc1ccc(C(=O)NO)cc1)CC3 CHEMBL5420243 IC50 2.1 nM
Nc1nn(-c2ccc3c(c2)OCO3)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5412296 IC50 2.1 nM
O=C(CCCCCCn1c(C(=O)NC2C3CC4CC(C3)CC2C4)cc2cc(Cl)ccc21)NO CHEMBL5180181 IC50 2.16 nM
C/C=C1\NC(=O)c2csc(n2)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622727 IC50 2.18 nM
O=C(/C=C/c1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc3ccccc3c2)cc1)NO CHEMBL4588104 IC50 2.189 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2ccnc(c2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593411 IC50 2.2 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4063500 IC50 2.2 nM
COc1ncc(-c2cc(OCCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1F CHEMBL4440596 IC50 2.2 nM
CCNC(=O)c1cccc(CN(C(=O)CCCCCC(=O)NO)c2ccc(OC)cc2)c1 CHEMBL4590525 IC50 2.2 nM
CCCN1CCC2(CC1)C[C@@H]2C(=O)N[C@@H](CCCCCC(=O)CC)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4640939 IC50 2.2 nM
Cn1cc(CN2CC3(CCN(c4ncc(C(=O)NO)cn4)C3)C2)c2ccc(C#N)cc21 CHEMBL5093798 IC50 2.2 nM
O=C(CCCCc1nnc(-c2cc3c([nH]c4ccccc43)c(-c3ccc(C(F)(F)F)cc3)n2)o1)NO CHEMBL5187023 IC50 2.2 nM
Cc1ccc(-c2nc(N)nc3c2cnn3CCCCCCC(=O)NO)o1 CHEMBL5169828 IC50 2.2 nM
CN(Cc1ccccc1)c1cc(NCCCCCCC(=O)NO)nc(-c2cccnc2)n1 CHEMBL5434760 IC50 2.2 nM
Nc1nn(-c2ccc(Br)cc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5393893 IC50 2.2 nM
CCOc1ccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL5430899 IC50 2.2 nM
COc1ccc(/C=N/NC(=O)CCCCCCCC(=O)NO)cc1 CHEMBL5269123 IC50 2.28 nM
CC(C)(C)OC(=O)NCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3317816 IC50 2.3 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccccn2)cc1)NO CHEMBL3758870 IC50 2.3 nM
Cc1ccccc1[C@H](C)Nc1c(NCCCCCC(=O)NO)c(=O)c1=O CHEMBL4245840 Ki 2.3 nM
Cc1ccc([C@H](C)Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4241014 Ki 2.3 nM
COc1ccc(N(Cc2cccc(C(=O)NCCc3ccc(F)cc3)c2)C(=O)CCCCCC(=O)NO)cc1 CHEMBL4468089 IC50 2.3 nM
Nc1ncc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4787267 IC50 2.3 nM
COc1ccc2c3c(oc2c1)CN([C@@H](C)C(=O)Nc1ccc(C(=O)NO)cc1)CC3 CHEMBL5423299 IC50 2.3 nM
O=C(CCCCCCn1cc(C(=O)NCc2ccc(Cl)cc2)c2ccccc21)NO CHEMBL5189457 IC50 2.31 nM
COc1ncc(-c2cc(OCCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cc1F CHEMBL4457009 IC50 2.4 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3n2)c1 CHEMBL4777182 IC50 2.4 nM
Nc1nc(-c2ccco2)c2cnn(CCCCCCC(=O)NO)c2n1 CHEMBL5197839 IC50 2.4 nM
O=C(CCCCCC(NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12)NO CHEMBL323869 IC50 2.5 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 2.5 nM
C[C@H](Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)c1ccccc1 CHEMBL4244537 Ki 2.5 nM
COc1ccc(-c2cc(OCCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cn1 CHEMBL4524198 IC50 2.5 nM
CCOC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4464421 IC50 2.5 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3cccc(C(F)(F)F)c3)ccc12)NO CHEMBL4782066 IC50 2.5 nM
CNC(=O)CCCCCCCn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21 CHEMBL4870348 IC50 2.5 nM
Nc1nn(-c2ccccc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5415232 IC50 2.5 nM
O=C(CCCCCCn1cc(C(=O)Nc2ccc(Cl)cc2Cl)c2ccccc21)NO CHEMBL5171183 IC50 2.53 nM
CCCC[C@H]1NC(=O)C[C@H]2/C=C/CCSSC[C@@H](NC1=O)C(=O)N[C@H](CC(C)C)[C@@H](O)CC(=O)O2 CHEMBL3218564 IC50 2.6 nM
O=C(CCCCCCn1cc(-c2ccc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2)nn1)NO CHEMBL3957055 IC50 2.6 nM
O=C(CCCCCCC(=O)Nc1ccc(Nc2ncc3ncn(C4CCCC4)c3n2)cc1)NO CHEMBL4074698 IC50 2.6 nM
CCN(CCOc1cc(-c2cnc(OC)c(F)c2)cc2c(C)ncnc12)c1ncc(C(=O)NO)cn1 CHEMBL4462934 IC50 2.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)nc2)[nH]1 CHEMBL4754237 IC50 2.6 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4782988 IC50 2.6 nM
COc1cc(OC)cc(N(CCCCCC(=O)NO)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 CHEMBL5179582 IC50 2.6 nM
Nc1nn(-c2ccc(Cl)cc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5439859 IC50 2.6 nM
CCn1c(CN(C)c2ncc(C(=O)NO)cn2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21 CHEMBL3828482 IC50 2.62 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccc(F)cc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4443998 IC50 2.64 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2cccc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593409 IC50 2.68 nM
C[C@@H]1NC(=O)[C@@]2(CCc3ccccc32)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C1=O CHEMBL390991 IC50 2.7 nM
O=C(CCCCCCC(=O)Nc1cccnc1)NO CHEMBL353581 Ki 2.7 nM
CCN(CC)Cc1ccc2cc(CN3CCN(c4ccc(C(=O)NO)cc4)C3=O)ccc2c1 CHEMBL3335006 IC50 2.7 nM
C[C@H](CCCCC(=O)NO)Nc1c(Nc2ccc(N(C)C)cc2)c(=O)c1=O CHEMBL4240163 Ki 2.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CCC(F)(F)F)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4643947 IC50 2.7 nM
COc1ncc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4799530 IC50 2.7 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccccc3Cl)ccc12)NO CHEMBL4792567 IC50 2.7 nM
COc1ccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)cc1 CHEMBL4788954 IC50 2.7 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(C/C=C/CN2C4CCC2c2cc(ccc24)-c2cnc1[nH]2)CC3 CHEMBL4854377 IC50 2.7 nM
COc1ccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL5409269 IC50 2.7 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622729 IC50 2.78 nM
Cc1[nH]c2ccccc2c1C1CCN(Cc2ccc(/C=C/C(=O)NO)cc2)C1 CHEMBL1089344 IC50 2.8 nM
Cc1ccc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc1 CHEMBL4288953 IC50 2.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4759472 IC50 2.8 nM
O=C(/C=C/c1ccc2cccnc2c1)NCCCCCC(=O)NO CHEMBL484073 IC50 2.9 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C(F)=C/CCS)NC1=O CHEMBL4446027 IC50 2.9 nM
COc1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4746599 IC50 2.9 nM
O=C(NO)c1ccc(CN2CCCc3cc(Cl)ccc32)cc1 CHEMBL4536605 IC50 2.9 nM
CC(C)c1ccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL5430562 IC50 2.9 nM
Nc1nn(-c2ccc(Cl)c(Cl)c2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5426015 IC50 2.9 nM
O=C(CCCCCCn1nc(C(=O)NC2C3CC4CC(C3)CC2C4)c2ccccc21)NO CHEMBL5180263 IC50 2.96 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(O[C@H]4CCOC4)c(Cl)c3)ncnc2s1)NO CHEMBL3339030 IC50 2.97 nM
COc1c(OCCCCCC(=O)NO)ccc2c1N=C(NC(=O)c1ccccc1)N1CCN=C21 CHEMBL5170300 IC50 2.98 nM
COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(=O)NO)c3ncc(-c4ccc5ccccc5c4)[nH]3)c2c1 CHEMBL445506 IC50 3.0 nM
O=C(CCCCCCC(=O)Nc1nc(-c2ccccc2)cs1)NO CHEMBL511212 IC50 3.0 nM
Cc1[nH]c2ccccc2c1CCN1CCCC1c1ccc(/C=C/C(=O)NO)cc1 CHEMBL1089700 IC50 3.0 nM
CC(C)(C)c1[nH]c2ccccc2c1C1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2)C1 CHEMBL1094042 IC50 3.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc3cc(F)ccc3n2)nc1 CHEMBL1801250 IC50 3.0 nM
Cc1nn2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819270 IC50 3.0 nM
CC(C)N(CCc1c(-c2ccccc2)nn2ccccc12)Cc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819275 IC50 3.0 nM
COc1ccc(C/C(=N\O)C(=O)NCCS)cc1OC CHEMBL2047698 IC50 3.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2C)c1 CHEMBL3356924 IC50 3.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Cc3c[nH]c4ccccc34)CC2)nc1 CHEMBL3891420 IC50 3.0 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4091353 IC50 3.0 nM
COc1ccc(-c2cc(OCCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cn1 CHEMBL4448002 IC50 3.0 nM
CCCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL4543309 IC50 3.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3c[nH]c(-c4ccccc4)n3)CCCC2)cc1 CHEMBL4640356 IC50 3.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cn[nH]c4)cc3)CCCC2)cc1 CHEMBL4633137 IC50 3.0 nM
COc1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCCC2)cc1-c1cn[nH]c1 CHEMBL4636523 IC50 3.0 nM
COc1ccc(F)c(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4799886 IC50 3.0 nM
COc1cc2c(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cc(-c3ccc(C)o3)nc2cc1OCCCN1CCCC1 CHEMBL4852593 IC50 3.0 nM
COc1cc2nc(C)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4848955 IC50 3.0 nM
COc1cc2nc(-c3ccccc3)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4847870 IC50 3.0 nM
COc1cc2nc(N3CCCCC3)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4858828 IC50 3.0 nM
CN1c2ccc(F)cc2C(=O)N2CCc3c([nH]c4ccc(OCCCCCCC(=O)NO)cc34)C21 CHEMBL5080403 IC50 3.0 nM
CCNNC(=O)c1ccc(CNC(=O)Nc2cccc3cccnc23)cc1 CHEMBL5189990 IC50 3.0 nM
CCC(=O)CCCCC[C@H](NC(=O)Cn1ccnn1)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5285418 IC50 3.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccc(O)cc3)nn2)c1)NO CHEMBL1088735 IC50 3.04 nM
Cc1ccc(-c2cc(-c3ccn(Cc4ccc(C(=O)NO)cc4)n3)ccn2)cc1 CHEMBL5406759 IC50 3.09 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccncc2)cc1)NO CHEMBL3758281 IC50 3.1 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc2c(C3CC3)c(N3CCNCC3)ccc2c1 CHEMBL3971229 IC50 3.1 nM
CN(C)C(=O)c1cc2cnc(Nc3cccc(NC(=O)CCCCCCC(=O)NO)c3)nc2n1C1CCCC1 CHEMBL4067088 IC50 3.1 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1cc(-c2ccccc2F)on1 CHEMBL4637836 IC50 3.1 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1F CHEMBL4776974 IC50 3.1 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccc(Cl)cc3)ccc12)NO CHEMBL4786350 IC50 3.1 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSC(=O)CCCCCCC)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622730 IC50 3.1 nM
COc1ccc2c3c(oc2c1)CN([C@@H](Cc1ccccc1)C(=O)Nc1ccc(C(=O)NO)cc1)CC3 CHEMBL5419989 IC50 3.1 nM
Nc1nn(-c2ccc(C(F)(F)F)cc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5396074 IC50 3.1 nM
O=C(CCCCCCn1c(C(=O)NC2C3CC4CC(C3)CC2C4)cc2ccc(Br)cc21)NO CHEMBL5171482 IC50 3.16 nM
CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](COCc2ccccc2)NC1=O CHEMBL241555 IC50 3.2 nM
O=C(/C=C/c1ccc(Cl)cc1F)NCCCCCC(=O)NO CHEMBL484489 IC50 3.2 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cncnc2)cc1)NO CHEMBL3758492 IC50 3.2 nM
CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)cc1 CHEMBL511749 IC50 3.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(C)nc2OC)[nH]1 CHEMBL4748516 IC50 3.2 nM
COc1cc2nc(NCCCCCC(=O)NO)nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC CHEMBL5201140 IC50 3.2 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CNC(=O)C1)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5285433 IC50 3.2 nM
CCC(=O)CCCCC[C@H](NC(=O)Cc1c(C)[nH]c2ccc(OC)cc12)c1ncc(-c2ccc3ccccc3c2)[nH]1 CHEMBL501319 IC50 3.2 nM
COc1cccc2oc3c(c12)CCN(CC(=O)Nc1ccc(C(=O)NO)cc1)C3 CHEMBL5421759 IC50 3.2 nM
Nc1nn(-c2cccc(Cl)c2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5399990 IC50 3.2 nM
CN(C)c1ccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL5409329 IC50 3.2 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3cccc(Cl)c3)ncnc2s1)NO CHEMBL3339020 IC50 3.24 nM
Cc1ccc(-c2cc(-c3ccn(Cc4ccc(C(=O)NO)cc4)n3)ccn2)c(F)c1 CHEMBL5399635 IC50 3.24 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCCN)NC2=O CHEMBL3317815 IC50 3.3 nM
COc1ncc(-c2cc(OCCCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cc1F CHEMBL4568675 IC50 3.3 nM
COc1ncc(-c2cc(OCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1F CHEMBL4437190 IC50 3.3 nM
CC(C)[C@H]1NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C)C(=O)N2)OC(=O)C[C@@H]1O CHEMBL3126832 IC50 3.3 nM
O=C(CCCCCCCNc1nc2cc(C(=O)O)ccc2c2cnccc12)NO CHEMBL4649511 IC50 3.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(C2=CC3SC=NC3C=C2)[nH]1 CHEMBL5220815 IC50 3.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)cc2)o1 CHEMBL5219118 IC50 3.3 nM
COc1cccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)c1 CHEMBL5416888 IC50 3.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC(F)(F)F)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4632432 IC50 3.4 nM
COc1ccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)cc1OC CHEMBL4793650 IC50 3.4 nM
O=C(NO)c1ccc(CN2CCCc3cc(F)c(Cl)cc32)cc1 CHEMBL4865650 IC50 3.4 nM
O=C(NO)c1ccc(CNC(=O)c2cc(-c3ccc(N4CCOCC4)cc3)cc3[nH]ccc23)cc1 CHEMBL5407953 IC50 3.4 nM
COc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)cc1Cl CHEMBL5435026 IC50 3.44 nM
O=C(CCCCC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccc2ncccc2c1)NO CHEMBL246189 IC50 3.5 nM
CC(/C=C/c1ccccc1)=C\C(=O)NCCCCCC(=O)NO CHEMBL490018 IC50 3.5 nM
CP(=O)(Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)OCc1cccnc1 CHEMBL470421 IC50 3.5 nM
COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OCCCCCC(=O)NO CHEMBL3633769 IC50 3.5 nM
O=C(CCCCC[C@@H](NC(=O)c1ccccc1)C(=O)Nc1ccc2ncccc2c1)NO CHEMBL4564170 IC50 3.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4649628 IC50 3.5 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4781191 IC50 3.5 nM
CCC(=O)CCCCC[C@H](NC(=O)C(C)(C)N(C)C)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5269165 IC50 3.5 nM
CN(C)Cc1ccc(-n2nc(N)c(C(=O)NCc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL5407078 IC50 3.5 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3o2)cc1 CHEMBL5078985 IC50 3.52 nM
COc1ccc(-c2cnc(-c3nc(C(=O)N[C@@H](C)c4ccc(C(=O)NO)cc4)c(C4CC4)s3)s2)cc1 CHEMBL4450360 IC50 3.57 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccccc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4460552 IC50 3.59 nM
O=C(CCCCCCOc1ccc2[nH]ccc2c1)NO CHEMBL426516 IC50 3.6 nM
O=C(NO)c1ccc(CN2CCCc3cc(Cl)c(Cl)cc32)cc1 CHEMBL4852645 IC50 3.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3ncccc3c2)[nH]1 CHEMBL5219241 IC50 3.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(C2=CC3OC=NC3C=C2)[nH]1 CHEMBL5221068 IC50 3.6 nM
C[C@@H]1NC(=O)[C@](C)(Cc2ccccc2)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C1=O CHEMBL393464 IC50 3.7 nM
COc1ccc(-c2cc(OCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cn1 CHEMBL4442688 IC50 3.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4632614 IC50 3.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(C(F)(F)F)cc2)nc1C#N CHEMBL4797893 IC50 3.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(OC)nc2OC)[nH]1 CHEMBL4754365 IC50 3.7 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3ccc(F)c(OCCO)c3)nc21)NO CHEMBL4740916 IC50 3.7 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3cccc(Cl)c3)ccc12)NO CHEMBL4792980 IC50 3.7 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3cccc(O)c3)c2)cc1 CHEMBL5419295 IC50 3.7 nM
COc1ccc(-c2cncc(C(=O)NCc3ccc(C(=O)NO)cc3)c2)cc1 CHEMBL5406671 IC50 3.72 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)c2)cc1 CHEMBL5436035 IC50 3.73 nM
Cc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)cc1 CHEMBL5428924 IC50 3.77 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3s2)cc1 CHEMBL5087431 IC50 3.79 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@H](/C=C/C(=O)NO)CC3)cc21 CHEMBL3309297 IC50 3.8 nM
CCN(CC)CCNC(=O)c1ccc(-c2cn(CCCCCCC(=O)NO)nn2)cc1 CHEMBL4096623 IC50 3.8 nM
CC(Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)C12CC3CC(CC(C3)C1)C2 CHEMBL4244764 Ki 3.8 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2ccnc(Nc3ccccc3)n2)cc1)NO CHEMBL4278951 IC50 3.8 nM
Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL1630208 IC50 3.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4788911 IC50 3.8 nM
Nc1nc2c(cnn2CCCCCCC(=O)NO)c2nc(-c3ccco3)nn12 CHEMBL5092198 IC50 3.8 nM
COc1cc2oc3c(c2cc1Cl)CCN(CC(=O)Nc1ccc(C(=O)NO)cc1)C3 CHEMBL5401785 IC50 3.8 nM
O=C(NO)c1ccc(CNC(=O)c2cnn(-c3ccccc3)n2)cc1 CHEMBL5401406 IC50 3.8 nM
CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL238829 IC50 3.9 nM
COc1cc2ccn(CCOc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)c2cc1OC CHEMBL4176214 IC50 3.9 nM
O=C(CCCCCCn1cc(-c2ccc(Nc3c4ccccc4nc4ccccc34)cc2)nn1)NO CHEMBL4241141 IC50 3.9 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(O)ccc3o2)cc1 CHEMBL5086141 IC50 3.91 nM
O=C(CCCCCC/C(=N\O)c1ccc(-c2ccccc2)cc1)NO CHEMBL95552 IC50 4.0 nM
O=C(NO)c1ccc(-c2ccc(CNCCc3cccc4occc34)cn2)s1 CHEMBL217246 IC50 4.0 nM
O=C(CCCCC[C@H](NC(=O)c1ccccn1)C(=O)Nc1cccc2cccnc12)NO CHEMBL391569 IC50 4.0 nM
COc1ccc(NC(=O)C(NCc2ccccc2)c2ccc3cc(C(=O)NO)sc3c2)cc1 CHEMBL254115 Inflection point 4.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(CN2CCC3(CCCN3)CC2)cc1 CHEMBL474890 IC50 4.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCN(C)CC1)c1ncc(-c2cnc3ccccc3c2)[nH]1 CHEMBL2448574 IC50 4.0 nM
Nc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 CHEMBL468935 IC50 4.0 nM
CC(C)N(CCc1c(C(C)(C)O)[nH]c2ccccc12)Cc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819261 IC50 4.0 nM
O=C(NCCS)/C(Cc1ccc(O)cc1)=N/O CHEMBL2047688 IC50 4.0 nM
CN(C)c1ccc(C/C(=N\O)C(=O)NCCS)cc1Br CHEMBL2047704 IC50 4.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 CHEMBL2417782 IC50 4.0 nM
Cn1cc(CCN2CCN(c3ccc(C(=O)NO)cc3)C2=O)c2ccccc21 CHEMBL3335008 IC50 4.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3356923 IC50 4.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)ccc2c1 CHEMBL3927842 IC50 4.0 nM
O=C(/C=C/c1ccc(CCNC(=O)c2ccc3ncccc3c2)cc1)NO CHEMBL4069152 IC50 4.0 nM
COc1ncc(-c2cc(OCCCNc3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cc1F CHEMBL4452585 IC50 4.0 nM
CN(C)c1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCC2)cc1 CHEMBL4636734 IC50 4.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cc[nH]n4)cc3)CCCC2)cc1 CHEMBL4646011 IC50 4.0 nM
Nc1cccc(-c2ccc(C3(C(=O)Nc4ccc(C(=O)NO)cc4)CCCC3)cc2)c1 CHEMBL4640407 IC50 4.0 nM
CN1c2ccc(F)cc2C(=O)N2CCc3c([nH]c4ccc(OCCCCCC(=O)NO)cc34)C21 CHEMBL5081732 IC50 4.0 nM
CN1c2ccc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cc2C(=O)N2CCc3c([nH]c4ccc(O)cc34)C21 CHEMBL5435505 IC50 4.0 nM
COc1cc2oc3c(c2cc1C)CCN(CC(=O)Nc1ccc(C(=O)NO)cc1)C3 CHEMBL5417556 IC50 4.0 nM
Nc1nn(-c2ccccc2)nc1C(=O)NCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL5418711 IC50 4.0 nM
Cc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)c(F)c1 CHEMBL5440196 IC50 4.08 nM
O=C(NO)c1ccc(CNC(=O)c2cncc(-c3ccccc3O)c2)cc1 CHEMBL5401496 IC50 4.09 nM
Nc1ncnc2c1c(-c1cnc3ccccc3c1)nn2CCCCCCC(=O)NO CHEMBL4860868 IC50 4.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc3ccncc3c2)[nH]1 CHEMBL5220120 IC50 4.1 nM
COc1ccc(-c2nc(C(=O)NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc1 CHEMBL5275259 IC50 4.1 nM
COC(=O)[C@@H]1Cc2cccc(c2)C[C@H](NC(C)=O)C(=O)N[C@@H](CCCCCC(=O)NO)C(=O)N1 CHEMBL388195 Ki 4.15 nM
Cc1ccc(Nc2nccc3ccc(NC(=O)CCCCCCC(=O)NO)cc23)cc1 CHEMBL3601333 IC50 4.17 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4550526 IC50 4.2 nM
COc1cc2nc(NCCCCCCC(=O)NO)nc(NC3CCN(C(C)C)CC3)c2cc1OC CHEMBL5204152 IC50 4.2 nM
Nc1nn(-c2cccc(F)c2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5415734 IC50 4.2 nM
C[C@@H](CCCCC(=O)NO)Nc1c(Nc2ccc(N(C)C)cc2)c(=O)c1=O CHEMBL4244362 Ki 4.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)c(F)cc2OC)[nH]1 CHEMBL4793832 IC50 4.3 nM
O=C(NO)c1ccc(CNC(=O)c2cncc(-c3ccc(C(F)(F)F)cc3)c2)cc1 CHEMBL5418093 IC50 4.33 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(C(F)(F)F)cc3)c2)cc1 CHEMBL5416264 IC50 4.36 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2coc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL2436595 IC50 4.4 nM
CC(C)[C@H]1NC(=O)[C@@H](C)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)C[C@@H]1O CHEMBL3650142 IC50 4.4 nM
Cc1ccccc1Nc1c(NCCCCCC(=O)NO)c(=O)c1=O CHEMBL4238532 Ki 4.4 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C(F)=C/CCS)OC1=O CHEMBL4529140 IC50 4.4 nM
C#Cc1cccc(Nc2cccc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL4637274 IC50 4.4 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3ccc(CO)cc3)nc21)NO CHEMBL4780827 IC50 4.4 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCCCCC(=O)NO)c4)nc3c2)c1 CHEMBL5187998 IC50 4.4 nM
O=C(CCCCCCC(=O)c1ccc(N2CCN(c3ccccc3)CC2)cc1)NO CHEMBL99216 IC50 4.5 nM
C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL598797 IC50 4.5 nM
CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)C2=N[C@@](Cc3ccccc3)(CS2)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL1171466 IC50 4.5 nM
COc1ccc2c(ccn2CCOc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c1 CHEMBL4159460 IC50 4.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3nccnc3cc2OC)[nH]1 CHEMBL5220576 IC50 4.5 nM
Cc1nn(-c2ccccc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5404095 IC50 4.5 nM
CN(C)c1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1F CHEMBL3339029 IC50 4.51 nM
CCN(CC)c1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1F CHEMBL3339028 IC50 4.57 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(-c3ccccc3)nn2)c1)NO CHEMBL1094709 IC50 4.6 nM
COc1ccccc1-c1ccc2c(NC(=O)CCCCCCC(=O)NO)n[nH]c2c1 CHEMBL4786063 IC50 4.6 nM
COc1cc(OC)cc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4788942 IC50 4.6 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(OC)ccc3[nH]2)cc1 CHEMBL5080511 IC50 4.66 nM
C[C@H]1CN2Cc3ccccc3C[C@@H]2C(=O)N[C@@H](CCCCCSSc2ccccn2)C(=O)NC(C)(C)C(=O)N1 CHEMBL238587 IC50 4.7 nM
CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)-c2nc(cs2)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL1173195 IC50 4.7 nM
COc1cc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL4278715 IC50 4.7 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)CNC1=O CHEMBL4776416 IC50 4.7 nM
O=C(NO)c1ccc(CN2CCN(c3ccnc(-c4ccc(N5CCOCC5)cc4)c3)CC2)cc1 CHEMBL5426091 IC50 4.74 nM
C[C@@H](Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)c1ccccc1 CHEMBL4251517 Ki 4.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1C[C@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645468 IC50 4.8 nM
O=C(NO)c1ccc(CN2CCCc3cc(Cl)c(F)cc32)cc1 CHEMBL4846263 IC50 4.8 nM
COc1ccccc1NC(=O)N[C@H](C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 CHEMBL5284956 IC50 4.8 nM
CCCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4526892 IC50 4.89 nM
O=C1N[C@@H]2CCCCCSSCCCCC[C@@H]1NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC2=O CHEMBL3310508 IC50 4.9 nM
COc1ncc(-c2cc(OCCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1NS(C)(=O)=O CHEMBL4458497 IC50 4.9 nM
O=C(NC(CCCCCSSCCO)C(=O)Nc1cccc2cccnc12)OCc1ccccc1 CHEMBL4438404 IC50 4.9 nM
O=C(CN1CCc2c(oc3ccccc23)C1)Nc1ccc(C(=O)NO)cc1 CHEMBL5438599 IC50 4.9 nM
O=C(CCCCCCC(=O)c1ccc2ccccc2c1)NO CHEMBL95273 IC50 5.0 nM
O=C(CCCCCCC(=O)c1ccc(-c2ccccc2)cc1)NO CHEMBL95313 IC50 5.0 nM
O=C(NO)c1ccc(-c2ccn(CCNCc3ccc4[nH]ccc4c3)n2)s1 CHEMBL218511 IC50 5.0 nM
O=C(NO)c1ccc(-c2ccn(CCNCc3ccc(-c4ccccn4)cc3)n2)s1 CHEMBL217004 IC50 5.0 nM
O=C(NO)c1ccc(C(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)cc1 CHEMBL250946 IC50 5.0 nM
Cc1[nH]c2ccccc2c1C1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2)C1 CHEMBL1089343 IC50 5.0 nM
Cc1c(-c2ccccc2)nc(-c2cccc(/C=C/C(=O)NO)c2)n1CCc1ccccc1 CHEMBL1095451 IC50 5.0 nM
Cc1c(-c2ccccc2)nc(-c2cccc(/C=C/C(=O)NO)c2)n1[C@@H]1CCCN(C)C1 CHEMBL1094648 IC50 5.0 nM
Cc1c(-c2ccccc2)nc(-c2cccc(/C=C/C(=O)NO)c2)n1[C@@H]1CCCN(C(C)C)C1 CHEMBL1096093 IC50 5.0 nM
Cc1nc(-c2cccc(/C=C/C(=O)NO)c2)n(CCc2ccccc2)c1Cc1ccccc1 CHEMBL1096705 IC50 5.0 nM
O=C(/C=C/c1ccc(CNCCc2c[nH]c3ncccc23)cc1)NO CHEMBL1819266 IC50 5.0 nM
N/N=C(\Cc1ccc(O)c(Br)c1)C(=O)NCCS CHEMBL2047680 IC50 5.0 nM
O=C(NCCS)/C(Cc1cc(Br)cc([N+](=O)[O-])c1)=N/O CHEMBL2047700 IC50 5.0 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2cccc(C(F)(F)F)c2)N1 CHEMBL3353927 IC50 5.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCC(=O)N2)c1 CHEMBL3356922 IC50 5.0 nM
O=C(NO)c1cnc(NC2(c3c(F)cccc3F)CC2)nc1 CHEMBL3655993 IC50 5.0 nM
Cc1[nH]ncc1-c1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCC2)cc1 CHEMBL4647467 IC50 5.0 nM
CC(=O)Nc1cccc(-c2ccc(C3(C(=O)Nc4ccc(C(=O)NO)cc4)CCCC3)cc2)c1 CHEMBL4646613 IC50 5.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cccnc4)cc3)CCCC2)cc1 CHEMBL4640593 IC50 5.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)cc(F)c2OC)[nH]1 CHEMBL4794196 IC50 5.0 nM
Nc1nc2cc(-c3nn(Cc4ccc(C(=O)NO)cc4)c4ncnc(N)c34)ccc2o1 CHEMBL4858368 IC50 5.0 nM
CN1C(=O)Cc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)ccc21 CHEMBL4848779 IC50 5.0 nM
COc1cc2nc(-c3cc(C)oc3C)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4850570 IC50 5.0 nM
Nc1nc(NCc2ccc(/C=C/C(=O)NO)cc2)nc2nc(-c3ccco3)nn12 CHEMBL5086912 IC50 5.0 nM
CN(C)c1ccc(C(=O)N(CC(=O)NCc2ccccc2)Cc2ccc(C(=O)NO)cc2)cc1 CHEMBL4170198 IC50 5.0 nM
CN(CCc1ccccc1)S(=O)(=O)c1cccc(/C=C/C(=O)NO)c1 CHEMBL5274004 IC50 5.0 nM
COc1cc(-n2cc(-c3cccc(NC(=O)CCCCCCC(=O)NO)c3)nn2)ccc1F CHEMBL1076939 IC50 5.06 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3cccc(N4CCOCC4)c3)c2)cc1 CHEMBL5403862 IC50 5.07 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)Nc1nc(-c2ccccc2)cs1)OCc1ccccc1 CHEMBL2022825 IC50 5.1 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(C(F)(F)F)cc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3828486 IC50 5.1 nM
O=C(CCCCCCn1cc(-c2cccc(Nc3c4ccccc4nc4ccccc34)c2)nn1)NO CHEMBL4240694 IC50 5.1 nM
O=C(NO)c1ccc(C(=O)N2CCCc3cc(F)ccc32)cc1 CHEMBL4852043 IC50 5.1 nM
CCCCN(Cc1ccc(C(=O)NO)cc1)C(=O)Nc1ccccc1 CHEMBL2179618 IC50 5.1 nM
Cc1[nH]c2ccccc2c1CCNS(=O)(=O)c1ccc(/C=C/C(=O)NO)cc1 CHEMBL3329991 IC50 5.13 nM
CCCNNC(=O)/C=C/c1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL4597954 IC50 5.17 nM
Cc1ccc(Oc2ccc(Nc3ncnc4ccc(-c5cn(CCCCCCC(=O)NO)nn5)cc34)cc2C)cn1 CHEMBL3893822 IC50 5.2 nM
COc1cccc(-c2nc(NCc3cccc(/C=C/C(=O)NO)c3)cc3c2[nH]c2ccccc23)c1 CHEMBL4453484 IC50 5.2 nM
O=C(/C=C/c1ccc(S(=O)(=O)Nc2cc(F)cc(F)c2)cc1)NO CHEMBL5283395 IC50 5.2 nM
Nc1nn(-c2ccccc2F)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5406785 IC50 5.2 nM
O=C(CCCCCN1C(=O)c2cccc3c(N4CCOCC4)ccc(c23)C1=O)NO CHEMBL4160632 IC50 5.25 nM
CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCc2ccccc2)NC1=O CHEMBL391384 IC50 5.3 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3cc(F)cc(F)c3)nn2)c1)NO CHEMBL1091815 IC50 5.3 nM
COc1ncc(-c2cc(OCCNc3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cc1F CHEMBL4459720 IC50 5.3 nM
Nc1nn(-c2ccc(F)cc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5414308 IC50 5.3 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(N4CCCCC4)c(F)c3)ncnc2s1)NO CHEMBL3339031 IC50 5.39 nM
O=C(NO)c1ccc(N2CCN(Cc3ccc4ccccc4c3)C2=O)cc1 CHEMBL3335004 IC50 5.4 nM
O=C(NO)c1ccc(N2CCN(Cc3cccc4ncccc34)C2=O)cc1 CHEMBL3335005 IC50 5.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637397 IC50 5.4 nM
COc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)c3cc[nH]c3c2)cc1 CHEMBL5420359 IC50 5.4 nM
COc1cc2oc3c(c2cc1F)CCN([C@@H](Cc1ccccc1)C(=O)Nc1ccc(C(=O)NO)cc1)C3 CHEMBL5409565 IC50 5.4 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccccc3O)c2)cc1 CHEMBL5424948 IC50 5.48 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCN)NC2=O CHEMBL3317814 IC50 5.5 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(N3CCOCC3)nc21)NO CHEMBL4752658 IC50 5.55 nM
O=C(CCCCCCn1cc(-c2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)nn1)NO CHEMBL3902778 IC50 5.6 nM
COc1cc(-c2nc(NCc3ccc(/C=C/C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL4534004 IC50 5.6 nM
COc1cc2oc3c(c2cc1F)CCN(CC(=O)Nc1ccc(C(=O)NO)cc1)C3 CHEMBL5440587 IC50 5.6 nM
O=C(NO)c1ccc(CNC(=O)c2ccnc(-c3ccc(OCc4ccccc4)cc3)c2)cc1 CHEMBL5412547 IC50 5.63 nM
NC(=O)C(N)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL437789 Activity 5.7 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3cc(CO)cc(CO)c3)nn2)c1)NO CHEMBL1088736 IC50 5.7 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCC(=O)Nc5ccc(C(=O)NO)cc5)c4)nc3c2)c1 CHEMBL5202912 IC50 5.7 nM
O=C(/C=C/c1cccc(S(=O)(=O)c2ccc3cccc(F)c3n2)c1)NO CHEMBL3925939 IC50 5.74 nM
O=C(CCCCCCC(=O)Nc1ccc2ccnc(Nc3ccc4ccccc4c3)c2c1)NO CHEMBL3601334 IC50 5.75 nM
Nc1ccc(-c2ccsc2)cc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL3664041 IC50 5.8 nM
CCn1cnc2c(NCc3cccc(/C=C/C(=O)NO)c3)nc(N3CCOCC3)nc21 CHEMBL4549278 IC50 5.8 nM
CN1CCC(C(=O)N[C@@H](CCCCCC(=O)c2nccs2)c2ncc(-c3ccc(F)cc3)[nH]2)CC1 CHEMBL4647458 IC50 5.8 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCCCCCCC)OC(=O)[C@H](CCCCN)NC1=O CHEMBL5086750 IC50 5.8 nM
COc1cc2nc(NCCCCCCC(=O)NO)nc(NC3CCN(C)CC3)c2cc1OC CHEMBL5187697 IC50 5.8 nM
COc1cc(OC)cc(N(CCCCCCC(=O)NO)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 CHEMBL5191916 IC50 5.8 nM
Nc1nn(-c2cccc3ccccc23)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5408897 IC50 5.8 nM
Cc1ccc(-c2cncc(C(=O)NCc3ccc(C(=O)NO)cc3)c2)c(F)c1 CHEMBL5440032 IC50 5.89 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=S)Nc3ccccc3)CC2)nc1 CHEMBL3952742 IC50 5.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(F)c2OC)[nH]1 CHEMBL4751762 IC50 5.9 nM
Nc1nc2cc(-c3nn(CC4CCN(C(=O)c5ccc(C(=O)NO)s5)CC4)c4ncnc(N)c34)ccc2o1 CHEMBL4879288 IC50 5.9 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCOc5ccc(C(=O)NO)cc5)c4)nc3c2)c1 CHEMBL5181688 IC50 5.9 nM
O=C(/C=C/c1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc(Cl)cc2)cc1)NO CHEMBL4574697 IC50 5.929 nM
Cc1ccc(-c2cncc(C(=O)NCc3ccc(C(=O)NO)cc3)c2)cc1 CHEMBL5431560 IC50 5.93 nM
O=C(CCCCC/C=C/c1ccc2ccccc2c1)NO CHEMBL451182 IC50 6.0 nM
Cn1c(CNCCn2ccc(-c3ccc(C(=O)NO)s3)n2)cc2ccccc21 CHEMBL216625 IC50 6.0 nM
O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1cccc(Cl)c1 CHEMBL216249 IC50 6.0 nM
O=C(NO)c1ccc(-c2ccc(CNCCc3ccccc3Cl)cn2)s1 CHEMBL387447 IC50 6.0 nM
C[C@@H](NC(=O)c1ccc(C(=O)NO)s1)c1ccccc1 CHEMBL496923 IC50 6.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CCN(CCO)C3)CC2)nc1 CHEMBL513250 IC50 6.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc2ccccc2c1)NO CHEMBL1085052 IC50 6.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc(Cl)cc2)nc1 CHEMBL1801238 IC50 6.0 nM
O=C(/C=C/c1ccc(CNCCc2cnn3ccccc23)cc1)NO CHEMBL1819269 IC50 6.0 nM
CCc1nn2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819271 IC50 6.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccccc3)o2)nc1 CHEMBL1834462 IC50 6.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3cccc(Cl)c3)o2)nc1 CHEMBL1834469 IC50 6.0 nM
COc1ccc(C/C(=N\N)C(=O)NCCS)cc1Br CHEMBL2047681 IC50 6.0 nM
COc1ccc(C(=O)N[C@H](COc2ccc(/C=C/C(=O)NO)cc2)Cc2c[nH]c3ccccc23)cc1 CHEMBL3233705 IC50 6.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)CNC(=O)O3)nc1 CHEMBL3286732 IC50 6.0 nM
COC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL400721 IC50 6.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc2c(c1)cc(C1CC1)n2CCN1CCOCC1 CHEMBL3952143 IC50 6.0 nM
CC(CCCCCC(=O)NO)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL4095596 IC50 6.0 nM
O=C(/C=C/c1ccc(CN2CCCC(c3c(-c4ccccc4)[nH]c4ccccc34)C2)cc1)NO CHEMBL1094041 IC50 6.0 nM
CC(C)c1[nH]c2ccccc2c1C1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2)C1 CHEMBL4455552 IC50 6.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3c[nH]c(-c4ccc([N+](=O)[O-])cc4)n3)CCCC2)cc1 CHEMBL4646320 IC50 6.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(Cl)c(Cl)c3)CCOCC2)cc1 CHEMBL4646451 IC50 6.0 nM
COc1ccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3n2)cc1 CHEMBL4776599 IC50 6.0 nM
COc1cc2c(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cc(-c3ccc(C)o3)nc2cc1OCC1CCNCC1 CHEMBL4876993 IC50 6.0 nM
Nc1ccccc1NC(=O)c1ccc(CNc2nc(-c3ccccc3)c(-c3ccccc3)o2)cc1 CHEMBL5282899 IC50 6.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4640923 IC50 6.1 nM
CCCc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3827489 IC50 6.15 nM
C=C(Cc1c[nH]c2ccccc12)Nc1ccc(OCCCCCCC(=O)NO)cc1 CHEMBL216181 IC50 6.2 nM
CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCc2ccccc2)NC1=O CHEMBL391383 IC50 6.2 nM
CCC(=O)CCCCC[C@H](NC(=O)C12CCN(CC1)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4741084 IC50 6.2 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(I)cc3F)ncnc2s1)NO CHEMBL3339018 IC50 6.24 nM
CCN1CCC[C@@H](n2c(-c3cccc(/C=C/C(=O)NO)c3)nc(-c3ccccc3)c2C)C1 CHEMBL1095136 IC50 6.3 nM
Cc1nc(-c2cccc(/C=C/C(=O)NO)c2)n([C@@H]2CCCN(C(C)C)C2)c1-c1ccccc1 CHEMBL1095120 IC50 6.3 nM
Cc1c(Cc2ccccc2)nc(-c2cccc(/C=C/C(=O)NO)c2)n1[C@@H]1CCCN(C)C1 CHEMBL1099049 IC50 6.3 nM
COc1ncc(-c2cc(OCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL4435527 IC50 6.3 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCCCCCCC(=O)NO)c4)nc3c2)c1 CHEMBL5202576 IC50 6.3 nM
COc1cc2oc3c(c2cc1OC)CCN(CC(=O)Nc1ccc(C(=O)NO)cc1)C3 CHEMBL5423769 IC50 6.3 nM
COc1ccc2c3c(oc2c1OC)CN(CC(=O)Nc1ccc(C(=O)NO)cc1)CC3 CHEMBL5404696 IC50 6.3 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C(F)(F)[C@@H](/C=C/CCS)NC1=O CHEMBL4516759 IC50 6.31 nM
CC(C)(C)OC(=O)N1CCC(COc2ccc(-c3cc(C(=O)NCc4ccc(C(=O)NO)cc4)ccn3)cc2)CC1 CHEMBL5429127 IC50 6.38 nM
CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](CO)NC1=O CHEMBL393961 IC50 6.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1ccc(OC)cc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4647014 IC50 6.4 nM
CCOP(=O)(CC)Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL511473 IC50 6.5 nM
C#Cc1cccc(Nc2ncnc3ccc(S(=O)(=O)n4ccc(/C=C/C(=O)NO)c4)cc23)c1 CHEMBL3218002 IC50 6.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(Cl)c2OC)[nH]1 CHEMBL4753648 IC50 6.5 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(-c2cn(CCc3ccccn3)nn2)cc1 CHEMBL5411914 IC50 6.5 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1cnc2c(ccn2CCN2CCOCC2)c1 CHEMBL3913445 IC50 6.8 nM
Cc1ccc(Oc2ccc(Nc3ncnc4ccc(-c5cn(CCCCCC(=O)NO)nn5)cc34)cc2C)cn1 CHEMBL3930762 IC50 6.9 nM
O=C(CCCCCCn1cc(-c2ncnc3[nH]ccc23)cn1)NO CHEMBL4060201 IC50 6.9 nM
CCOC(=O)C1CC1c1ccc(OC)c(-c2cnc([C@H](CCCCCC(=O)CC)NC(=O)[C@H]3CC34CCN(CC)CC4)[nH]2)c1 CHEMBL4788187 IC50 6.9 nM
O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1cccc2cccnc12 CHEMBL386473 IC50 7.0 nM
O=C(NO)c1ccc(-c2ccc(CNCc3ccccc3Cl)cn2)s1 CHEMBL386914 IC50 7.0 nM
O=C(NO)c1ccc(-c2ccc(CNCc3ccc(-c4ccccc4)cc3)cn2)s1 CHEMBL218392 IC50 7.0 nM
CCOC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL399494 IC50 7.0 nM
CC(=O)Nc1ccc(C(=O)Nc2cc(-c3ccsc3)ccc2N)cc1 CHEMBL407560 IC50 7.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)CNC(=O)N3)nc1 CHEMBL486152 IC50 7.0 nM
CCP(=O)(Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)OC CHEMBL472636 IC50 7.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccc(F)cc3)s2)nc1 CHEMBL1834477 IC50 7.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3cccc(Cl)c3)s2)nc1 CHEMBL1834480 IC50 7.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@@H](C)n2nncc2[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL2012817 IC50 7.0 nM
O=C(NCCS)/C(Cc1ccc(F)cc1)=N/O CHEMBL2047689 IC50 7.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3098604 IC50 7.0 nM
O=C1NC[C@@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356925 IC50 7.0 nM
O=C1NCCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356527 IC50 7.0 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 Ki 7.0 nM
O=C(NO)c1cnc(NC2(c3cc(C(F)(F)F)ccc3F)CC2)nc1 CHEMBL3655995 IC50 7.0 nM
O=C(CCCCCn1cc(-c2ccc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2)nn1)NO CHEMBL3920583 IC50 7.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)cnc2c1 CHEMBL3899844 IC50 7.0 nM
CC(C)n1cnc2c(NCc3cccc(/C=C/C(=O)NO)c3)nc(N3CCOCC3)nc21 CHEMBL4476140 IC50 7.0 nM
Cc1[nH]c2ccc(N3CCOCC3)cc2c1C1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2)C1 CHEMBL4531791 IC50 7.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(Br)cc3)CCCC2)cc1 CHEMBL4647859 IC50 7.0 nM
COc1cc2c(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cc(C)nc2cc1OCCCN1CCCC1 CHEMBL4865830 IC50 7.0 nM
COc1cc2nc(-c3ccc(C)o3)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4856110 IC50 7.0 nM
COc1cc2nc(-c3ccc(C)o3)nc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4854765 IC50 7.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)CCCCCC(=O)Nc1ccccc1 CHEMBL5410602 Ki 7.0 nM
COc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)cc1OC CHEMBL5424227 IC50 7.08 nM
O=C(NO)c1cnc(N2CCN(C(/C=C/c3ccc(F)cc3)CO)CC2)nc1 CHEMBL594544 IC50 7.1 nM
CN1CCN(CCn2ncc3cc(C(=O)Nc4cc(-c5ccccc5)ccc4N)ccc32)CC1 CHEMBL3983272 IC50 7.1 nM
COc1cccc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)c1 CHEMBL4285608 IC50 7.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCC(N(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645863 IC50 7.1 nM
Nc1nc(-c2ccco2)c2cnn(Cc3ccc(/C=C/C(=O)NO)cc3)c2n1 CHEMBL5185100 IC50 7.1 nM
O=C(/C=C/c1ccc(CCNC(=O)c2ccc3c(c2)OCO3)cc1)NO CHEMBL4078380 IC50 7.18 nM
Cc1ccc(-c2cncc(C(=O)NCc3ccc(C(=O)NO)cc3)c2)c(C)c1 CHEMBL5413316 IC50 7.18 nM
O=C(CCCCCn1cc(-c2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)nn1)NO CHEMBL3939771 IC50 7.2 nM
CCC(=O)CCCCCC(NC(=O)c1cncs1)c1[nH]c(-c2ccccc2)nc1C(N)=O CHEMBL4742036 IC50 7.2 nM
Cc1ccc(-c2nc(N)nc3c2cnn3CCCCCCCC(=O)NO)o1 CHEMBL5202905 IC50 7.2 nM
O=C(CCCCCNc1c(NCc2ccccc2)c(=O)c1=O)NO CHEMBL4248346 Ki 7.3 nM
Nc1ccc(-c2nn(CCCCCCC(=O)NO)c3ncnc(N)c23)cn1 CHEMBL4872747 IC50 7.3 nM
Cc1ccc(-c2nc(N)nc3c2cnn3CCCCCC(=O)NO)o1 CHEMBL5205993 IC50 7.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cn(C)nc3cc2OC)o1 CHEMBL5218487 IC50 7.3 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc2c(cnn2CCN2CCOCC2)c1 CHEMBL3922439 IC50 7.4 nM
Nc1nc(NCCOc2ccc(C(=O)NO)cc2)nc2nc(-c3ccco3)nn12 CHEMBL5080901 IC50 7.4 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(OC)ccc3o2)cc1 CHEMBL5093099 IC50 7.4 nM
O=C(NO)c1ccc(NC(=O)[C@H](Cc2ccccc2)N2CCc3c(oc4cc5c(cc34)OCO5)C2)cc1 CHEMBL5403974 IC50 7.4 nM
CC(C)(C)c1[nH]c2ccccc2c1[C@H]1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2F)C1 CHEMBL1093033 IC50 7.5 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCC1c2ccccc2-c2ccccc21)OCc1ccccc1 CHEMBL2022829 IC50 7.6 nM
O=C(CCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2ncccc2c1)NO CHEMBL246390 IC50 7.7 nM
CCOP(=O)(CNCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)OCC CHEMBL470225 IC50 7.7 nM
CC/C=C\CCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830536 Ki 7.7 nM
Nc1nc(NCCCCCCC(=O)NO)nc2nc(-c3ccco3)nn12 CHEMBL5090351 IC50 7.7 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3cccc(Cl)c3F)ncnc2s1)NO CHEMBL3339019 IC50 7.78 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1cnc2c(C3CC3)c(N3CCNCC3)ccc2c1 CHEMBL3951875 IC50 7.8 nM
O=C(/C=C/c1ccc(CCNC(=O)c2ccc3[nH]cnc3c2)cc1)NO CHEMBL4076931 IC50 7.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc([N+](=O)[O-])ccc2OC)[nH]1 CHEMBL4757813 IC50 7.8 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Br)ccc3o2)cc1 CHEMBL5083475 IC50 7.85 nM
O=C(/C=C/c1cccc(-c2nc3ccccc3n2CCc2ccccc2)c1)NO CHEMBL1099096 IC50 7.9 nM
Cc1nc(-c2cccc(/C=C/C(=O)NO)c2)n(CCc2ccccc2)c1-c1ccccc1 CHEMBL1096433 IC50 7.9 nM
CCN1CCC[C@@H](n2c(-c3cccc(/C=C/C(=O)NO)c3)nc(C)c2-c2ccccc2)C1 CHEMBL1095119 IC50 7.9 nM
Cc1c(Cc2ccccc2)nc(-c2cccc(/C=C/C(=O)NO)c2)n1CCc1ccccc1 CHEMBL1099048 IC50 7.9 nM
Cc1nc(-c2cccc(/C=C/C(=O)NO)c2)n(CCc2ccccc2)c1C CHEMBL1095719 IC50 7.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCOCC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4649561 IC50 7.9 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)ncc1Cl CHEMBL4855319 IC50 7.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nccnc3c2)[nH]1 CHEMBL5219811 IC50 7.9 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccccc3c2)cc1 CHEMBL5084347 IC50 7.98 nM
C=C(CCCCCCC(=O)NO)c1ccc2ccccc2c1 CHEMBL95535 IC50 8.0 nM
O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1cc(F)cc(F)c1 CHEMBL216248 IC50 8.0 nM
COc1ccccc1NC(=O)Cn1ccc(-c2ccc(C(=O)NO)s2)n1 CHEMBL426343 IC50 8.0 nM
O=C(NO)c1ccc(-c2ccc(CNCc3ccc4c(c3)OCO4)cn2)s1 CHEMBL216463 IC50 8.0 nM
Cc1ccccc1CCNCc1ccc(-c2ccc(C(=O)NO)s2)nc1 CHEMBL441699 IC50 8.0 nM
O=C(NO)c1ccc(-c2ccc(CNCCc3c[nH]c4ccccc34)cn2)s1 CHEMBL385562 IC50 8.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CNC(=O)OCc2ccccn2)cc1 CHEMBL253870 IC50 8.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CCNC3)CC2)nc1 CHEMBL513568 IC50 8.0 nM
CS(=O)(=O)N1CCC2(CCN(c3ccc(C(=O)Nc4cc(-c5cccs5)ccc4N)cn3)CC2)C1 CHEMBL470582 IC50 8.0 nM
CC(=O)N1CCC2(CCCN(c3ccc(C(=O)Nc4cc(-c5cccs5)ccc4N)cn3)C2)C1 CHEMBL471399 IC50 8.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)COC(=O)N3)nc1 CHEMBL486770 IC50 8.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CN2CCC3(CCCN3)CC2)cc1 CHEMBL475692 IC50 8.0 nM
Nc1ccc(-c2ccsc2)cc1NC(=O)c1ccc(CN2CCC3(CCCN3)CC2)cc1 CHEMBL514304 IC50 8.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(C(=O)N2CCC3(CCCN3)CC2)cc1 CHEMBL473484 IC50 8.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCN(C)CC1)c1ncc(-c2cc3ccccc3cn2)[nH]1 CHEMBL2448573 IC50 8.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cnc3ccccc3n2)[nH]1 CHEMBL2448572 IC50 8.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2F)[nH]1 CHEMBL2448575 IC50 8.0 nM
CC(=O)NCCCCC[C@@H]1NC(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2cccc3ccccc23)NC(=O)[C@H](CCCCCC(=O)O)NC1=O CHEMBL569174 IC50 8.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(I)cc3)nn2)c1)NO CHEMBL1091475 IC50 8.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(I)cc1)NO CHEMBL1083088 IC50 8.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 8.0 nM
Cc1[nH]c2nccnc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL1819264 IC50 8.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccccc3Cl)o2)nc1 CHEMBL1834468 IC50 8.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccccc3)s2)nc1 CHEMBL1834472 IC50 8.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccccc3Cl)s2)nc1 CHEMBL1834479 IC50 8.0 nM
CC(C)C[C@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCCCC(=O)NO)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1 CHEMBL566637 IC50 8.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H](C)NC(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2cccc3ccccc23)NC1=O CHEMBL2012815 IC50 8.0 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(C)=O)C[C@@H]3O[C@H]1C[C@H](NCc2ccc(-c3cn(CCCCCCC(=O)NO)nn3)cc2)[C@H](O)[C@H](C)O1 CHEMBL2023529 IC50 8.0 nM
O=C1C[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356929 IC50 8.0 nM
Cc1ccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)cc1 CHEMBL3356917 IC50 8.0 nM
Cc1ccccc1-c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 CHEMBL3758191 IC50 8.0 nM
CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(c5ncc(C(=O)NO)cn5)CC4)ccc3OCC)nc12 CHEMBL3970984 IC50 8.0 nM
Cc1n[nH]c(C)c1-c1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCC2)cc1 CHEMBL4633570 IC50 8.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4ccc5[nH]ccc5c4)cc3)CCCC2)cc1 CHEMBL4648856 IC50 8.0 nM
O=C(NCCSSCCNC(=O)/C(Cc1ccc(O)c(Br)c1)=N/O)/C(Cc1ccc(O)c(Br)c1)=N/O CHEMBL83747 IC50 8.0 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCCCCCCC)OC(=O)[C@H](CCCCNC(=O)CCCCC[N+]2=C(/C=C/C=C/C=C3/N(CC)c4ccc5c(S(=O)(=O)O)cc(S(=O)(=O)O)cc5c4C3(C)C)C(C)(C)c3c2ccc2c(S(=O)(=O)[O-])cc(S(=O)(=O)O)cc32)NC1=O CHEMBL5076242 IC50 8.0 nM
Nc1nc2c(cnn2CCc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c2nc(-c3ccco3)nn12 CHEMBL5093149 IC50 8.0 nM
CC(C)[C@@H]1NC(=O)[C@H]2CCCCCSSCCCCC[C@H](NC(=O)[C@H]3CCCN3C1=O)C(=O)N2 CHEMBL3310507 IC50 8.1 nM
COc1cc(C(=O)NCCc2ccc(/C=C/C(=O)NO)cc2)ccc1O CHEMBL4102654 IC50 8.1 nM
COc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)cn1 CHEMBL5432401 IC50 8.16 nM
O=C(CCCCCn1cc(-c2ccc(Nc3c4ccccc4nc4ccccc34)cc2)nn1)NO CHEMBL4237410 IC50 8.2 nM
COc1ccc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc1OC CHEMBL4290063 IC50 8.2 nM
COc1ccc(N(Cc2noc(-c3ccccc3)n2)C(=O)CCCCCC(=O)NO)cc1 CHEMBL4465444 IC50 8.2 nM
O=C(NC(CCCCCSSCCCCCC(NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12)C(=O)Nc1cccc2cccnc12)OCc1ccccc1 CHEMBL4543038 IC50 8.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccnc2OC)[nH]1 CHEMBL4753639 IC50 8.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(c2)C2CCC3C2)[nH]1 CHEMBL4859950 IC50 8.2 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(-c2cn(C[S+]([O-])c3ccccc3)nn2)cc1 CHEMBL5400421 IC50 8.2 nM
COc1ccc(-c2cc(N3CCN(Cc4ccc(C(=O)NO)cc4)CC3)ccn2)cc1 CHEMBL5416658 IC50 8.21 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(F)ccc3o2)cc1 CHEMBL5093836 IC50 8.22 nM
O=C(CCCCCCn1cc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)nn1)NO CHEMBL3911796 IC50 8.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1C[C@@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4641048 IC50 8.3 nM
Cc1coc(C(=O)CCCCC[C@H](NC(=O)C2CCN(C)CC2)c2ncc(-c3ccc(F)cc3)[nH]2)n1 CHEMBL4633968 IC50 8.3 nM
O=C(CCCCCCC(=O)N/N=C/c1cnc(N(c2ccccc2)c2ccccc2)nc1)NO CHEMBL5188297 IC50 8.35 nM
O=C(CCCCCCC(=O)N/N=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1)NO CHEMBL5075729 IC50 8.35 nM
COc1cc2nc(NCCCCCC(=O)NO)nc(NC3CCN(C(C)C)CC3)c2cc1OC CHEMBL5171881 IC50 8.4 nM
Nc1nc(-c2ccco2)c2cnn(Cc3cccc(/C=C/C(=O)NO)c3)c2n1 CHEMBL5208818 IC50 8.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cn(C)c3ccccc3c2=O)[nH]1 CHEMBL5218749 IC50 8.4 nM
O=C(CCCCCC/C(=N\O)c1ccc2ccccc2c1)NO CHEMBL96984 IC50 8.5 nM
O=C(CCCCCCC(=O)Nc1nc(-c2cccc([N+](=O)[O-])c2)cs1)NO CHEMBL387924 IC50 8.5 nM
O=C(CCCCCn1cnc2c(N3CCOCC3)nc(-c3ccc(F)c(O)c3)nc21)NO CHEMBL4789497 IC50 8.5 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(C3CCCCC3)nn2)c1)NO CHEMBL1094707 IC50 8.6 nM
CC[C@H](NC(=O)c1nn(-c2ccccc2)nc1N)c1ccc(C(=O)NO)cc1 CHEMBL5418707 IC50 8.6 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(C(F)(F)F)cc3)nn2)c1)NO CHEMBL1088734 IC50 8.7 nM
O=C(/C=C/c1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc(I)cc2)cc1)NO CHEMBL4563800 IC50 8.71 nM
CN(C)C(=O)C(N)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL258132 Activity 8.8 nM
CC(C)C[C@H](NC(=O)CNC(=O)c1cccc(/C=C/C(=O)NO)c1)B1O[C@@H]2[C@@H]3C[C@H](C[C@]2(C)O1)C3(C)C CHEMBL4576202 IC50 8.8 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3cn2)cc1 CHEMBL5086924 IC50 8.8 nM
COc1ncc(-c2cc(OCCCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL4465475 IC50 8.9 nM
O=C(N[C@@H](CCCCNC(=O)c1ccccc1O)c1ncc(-c2ccc3ccccc3c2)[nH]1)c1cncs1 CHEMBL4753019 IC50 8.9 nM
COc1ccc2c3c(oc2c1)CN(Cc1ccc(/C=C/C(=O)NO)cc1)CC3 CHEMBL5401051 IC50 8.9 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Cl)ccc3o2)cc1 CHEMBL5089712 IC50 8.91 nM
O=C(CCCCCCn1cc(C(=O)N2CCOCC2)c2ccccc21)NO CHEMBL5173771 IC50 8.95 nM
O=C(NO)c1ccc(-c2ccn(CCNCc3ccc(-n4ccnc4)cc3)n2)s1 CHEMBL217098 IC50 9.0 nM
O=C(NO)c1ccc(-c2ccc(CCNCc3ccccc3)cn2)s1 CHEMBL217097 IC50 9.0 nM
O=C(NO)c1ccc(-c2ccc(CNCc3ccc(Cl)cc3)cn2)s1 CHEMBL217881 IC50 9.0 nM
O=C(NO)c1ccc(-c2ccc(CNCCc3ccc(F)cc3)cn2)s1 CHEMBL216300 IC50 9.0 nM
Cc1cccc(CCNCc2ccc(-c3ccc(C(=O)NO)s3)nc2)c1 CHEMBL436964 IC50 9.0 nM
O=C(NO)c1ccc(-c2ccc(CCNCc3ccc4c(c3)OCO4)cn2)s1 CHEMBL217615 IC50 9.0 nM
CCCC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL251817 IC50 9.0 nM
CCC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL251819 IC50 9.0 nM
CC(=O)N1CCC2(CCN(c3ccc(C(=O)Nc4cc(-c5cccs5)ccc4N)cn3)CC2)C1 CHEMBL471414 IC50 9.0 nM
CCP(=O)(CC)Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL513536 IC50 9.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2ccccc2)c1)NO CHEMBL473270 IC50 9.0 nM
Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1 CHEMBL272980 Ki 9.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccc(Cl)cc3)o2)nc1 CHEMBL1834461 IC50 9.0 nM
O=C(NO)c1cnc(Nc2nnc(-c3ccc(F)cc3)o2)nc1 CHEMBL1834466 IC50 9.0 nM
CN(C)c1ccc(-c2nnc(Nc3ncc(C(=O)NO)cn3)o2)cc1 CHEMBL1834471 IC50 9.0 nM
O=C(CCCCCCC(=O)Nc1ccc([19F])cc1)NO CHEMBL1923808 IC50 9.0 nM
COc1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCCC2)cc1-c1ccccc1NC(C)=O CHEMBL4646610 IC50 9.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc([N+](=O)[O-])cc3)CCOCC2)cc1 CHEMBL4643094 IC50 9.0 nM
COc1cc2c(NCc3ccc(C(=O)NO)cc3)cc(-c3ccc(C)o3)nc2cc1OCCCN1CCCC1 CHEMBL4872188 IC50 9.0 nM
O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@@H]2CCCCCCCCC[C@@H](NC1=O)C(=O)N2)NO CHEMBL598363 IC50 9.1 nM
O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@@H]2CCCCCCCCCC[C@@H](NC1=O)C(=O)N2)NO CHEMBL592719 IC50 9.1 nM
CC1(C)CC(=O)Nc2ccc(NC(=O)CCCCCCC(=O)NO)cc21 CHEMBL3311466 IC50 9.1 nM
CCC(=O)CCCCC[C@@H]1NC(=O)C2CCCCN2C(=O)[C@H](C(C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL4099599 IC50 9.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(C(=O)NC3CCOC3)cc2)[nH]1 CHEMBL4761389 IC50 9.1 nM
O=C(CCCCCC(=O)NCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1)NO CHEMBL4288076 IC50 9.2 nM
COc1ccc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc1 CHEMBL4278270 IC50 9.3 nM
COc1ccc(-c2nc(NCc3cccc(/C=C/C(=O)NO)c3)cc3c2[nH]c2ccccc23)cc1OC CHEMBL4472365 IC50 9.3 nM
Nc1nc(-c2ccco2)c2cnn(CCCCCC(=O)NO)c2n1 CHEMBL5207324 IC50 9.3 nM
Nc1nc(-c2ccco2)c2cnn(CCCCCCCC(=O)NO)c2n1 CHEMBL5169338 IC50 9.3 nM
O=C(CCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621296 IC50 9.37 nM
O=C(CCCCC[C@H](NC(=O)c1ccccc1)C(=O)Nc1cccc2cccnc12)NO CHEMBL246587 IC50 9.4 nM
C[C@@H]1NC(=O)C(C)(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C1=O CHEMBL238596 IC50 9.4 nM
CC[C@H](Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)c1ccccc1 CHEMBL4241594 Ki 9.4 nM
Nc1nn(-c2cccc(Cl)c2Cl)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5400387 IC50 9.4 nM
O=C(CCCCCCC(=O)c1ccc(N2CCCCC2)cc1)NO CHEMBL99877 IC50 9.5 nM
O=C(CCCCCC(=O)N(CC(=O)Nc1nc2ccccc2s1)CC(=O)Nc1nc2ccccc2s1)NO CHEMBL270739 IC50 9.5 nM
CN(C)c1cccc(CN2CCN(c3ccc(C(=O)NO)cc3)C2=O)c1 CHEMBL3335000 IC50 9.5 nM
O=C(NO)c1ccc(N2CCN(Cc3cccc4ccccc34)C2=O)cc1 CHEMBL3335003 IC50 9.5 nM
CC(=O)N(Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)Cc1cn(C)nn1 CHEMBL3664140 IC50 9.5 nM
CCCNNC(=O)c1ccc(NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(OC)cc2)cc1 CHEMBL4063938 IC50 9.54 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccccc3)ccc12)NO CHEMBL4782327 IC50 9.6 nM
COc1ccc(-c2nc(NCc3cccc(/C=C/C(=O)NO)c3)cc3c2[nH]c2ccccc23)cc1 CHEMBL4460364 IC50 9.7 nM
O=C(N[C@@H](CCCCNC(=O)c1c(O)cccc1F)c1ncc(-c2ccc3ccccc3c2)[nH]1)c1cncs1 CHEMBL4753111 IC50 9.7 nM
CCCNNC(=O)c1ccc(CNC(=O)c2nc3ccccc3s2)cc1 CHEMBL5084847 IC50 9.73 nM
CCN1CCN(Cc2cnc(-c3ccc(C(=O)Nc4ccccc4N)cc3)c(C#N)c2)CC1 CHEMBL256985 Log IC50 9.772 nM
N#Cc1cc(CN2CCC2)cnc1-c1ccc(C(=O)Nc2ccccc2N)cc1 CHEMBL403813 Log IC50 9.772 nM
Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cnnn2CCCCCCCC(=O)NO)c1 CHEMBL2408780 Ki 9.8 nM
Nc1nn(-c2cc(Cl)cc(Cl)c2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5414925 IC50 9.8 nM
O=C(Nc1cc(-c2ccccc2)ccc1O)c1ccc(CNc2ccncc2)cc1 CHEMBL474903 IC50 9.9 nM