Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 Ki 0.05 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCC/C=C/[C@@H]2CC(=O)NCc3nc(cs3)C3=N[C@@](C)(CS3)C(=O)N[C@@H](C(C)C)C(=O)O2)OC1=O CHEMBL3329621 IC50 0.2 nM
CC(C)[C@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL1796689 IC50 0.5 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)OC1=O CHEMBL3329622 IC50 0.5 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593247 IC50 0.5 nM
C[C@@H]1CN(C(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cnn(CCCCCCC(=O)NO)c4n3)cc2)CCO1 CHEMBL4532398 IC50 0.58 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccncc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827517 IC50 0.86 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL343448 IC50 0.9 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356916 IC50 1.0 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3310505 IC50 1.0 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 IC50 1.0 nM
COc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4237803 Ki 1.2 nM
Nc1ccc(-c2nc(N3CCOCC3)c3cnn(CCCCCCC(=O)NO)c3n2)cc1 CHEMBL4552057 IC50 1.43 nM
Nc1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4785064 IC50 1.7 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccccc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4460552 IC50 1.98 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2C)c1 CHEMBL3356924 IC50 2.0 nM
Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 IC50 2.0 nM
CCOC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4464421 IC50 2.1 nM
Nc1ncc(-c2nc(N3CCOCC3)c3ccn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4744689 IC50 2.3 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21)NO CHEMBL4749655 IC50 2.5 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827814 IC50 2.8 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 2.8 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ccc(C(=O)NO)cc4)cc3n2)cn1 CHEMBL5278968 IC50 2.8 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827894 IC50 2.83 nM
O=C(CCCCCCc1nc2ccc(Br)cc2[nH]1)NO CHEMBL2414098 IC50 3.0 nM
CC(C)(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4241370 Ki 3.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSCCS)OC1=O CHEMBL4078721 IC50 3.6 nM
O=C(CCCCCCn1cc(Nc2ncc3ccn(Cc4ccccc4F)c3n2)cn1)NO CHEMBL5076728 IC50 3.6 nM
Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL1630208 IC50 3.7 nM
C/C=C1\NC(=O)[C@@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL146250 IC50 3.9 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 pIC50 3.981 nM
O=C(NO)c1ccc(Cn2cc(CN3CCCC3)c3ccccc32)cc1 CHEMBL4578278 pIC50 3.981 nM
CN(C)Cc1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL4066920 pIC50 3.981 nM
Cc1ccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)cc1 CHEMBL3356917 IC50 4.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3356923 IC50 4.0 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 4.3 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCC(=O)N2)c1 CHEMBL3356922 IC50 5.0 nM
O=C1NC[C@@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356925 IC50 5.0 nM
CN1CCCC1c1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL4532181 pIC50 5.012 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4550526 IC50 5.7 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3cc(CO)cc(CO)c3)nn2)c1)NO CHEMBL1088736 IC50 5.8 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 CHEMBL2417782 IC50 6.0 nM
CN1C(=O)CCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356526 IC50 6.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(-c3ccccc3)nn2)c1)NO CHEMBL1094709 IC50 6.8 nM
COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3828518 IC50 6.85 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2cccc(C(F)(F)F)c2)N1 CHEMBL3353927 IC50 7.0 nM
O=C1NC[C@H](c2ccccc2)[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356926 IC50 7.0 nM
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2/C=N/OCCCCCC(=O)NCCSSCCNC(=O)/C(Cc1ccc(O)c(Br)c1)=N\O CHEMBL4290191 IC50 7.55 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 IC50 8.41 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 9.0 nM
O=C1NCCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356527 IC50 9.0 nM
O=C1C[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356929 IC50 9.0 nM
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccc(O)cc1c2/C=N/OCCCCCC(=O)NCCSSCCNC(=O)/C(Cc1ccc(O)c(Br)c1)=N\O CHEMBL4280303 IC50 9.12 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(C3CCCCC3)nn2)c1)NO CHEMBL1094707 IC50 9.8 nM
CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL257972 Ki 10.0 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL3098602 IC50 10.6 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(I)cc3)nn2)c1)NO CHEMBL1091475 IC50 10.7 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3353925 IC50 11.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356523 IC50 11.0 nM
O=C1NCCC[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356915 IC50 11.0 nM
O=C1CC[C@@H](C(=O)N[C@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356919 IC50 11.0 nM
COc1ccc(/C=N/NC(=O)CCCCCCCC(=O)NO)cc1 CHEMBL5269123 IC50 11.05 nM
O=C(CCCCCCC(=O)Nc1nc(-c2cccc([N+](=O)[O-])c2)cs1)NO CHEMBL387924 IC50 11.1 nM
CN1CCc2c(c3ccccc3n2Cc2ccc(C(=O)NO)cc2)C1 CHEMBL2018302 pIC50 12.59 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(CC(O)c3cccc(Br)c3)nn2)c1)NO CHEMBL483893 IC50 13.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(C)C CHEMBL1830424 Ki 13.0 nM
COc1cc(OC)c2c(N3CCN(C)CC3)nc(-c3cc(C)c(OCCCCCC(=O)NO)c(C)c3)nc2c1 CHEMBL4781177 IC50 13.24 nM
O=C1NC[C@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356927 IC50 14.0 nM
O=C1NC[C@@H](c2ccccc2)[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356928 IC50 14.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(C(F)(F)F)cc3)nn2)c1)NO CHEMBL1088734 IC50 14.5 nM
O=C1CC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356918 IC50 15.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2CC(O)c2cccc(Br)c2)c1)NO CHEMBL487107 IC50 15.8 nM
CN(C)Cc1nn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL4470067 pIC50 15.85 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(C3CCCCC3)nn2)c1)NO CHEMBL1094710 IC50 16.6 nM
Nc1cccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)c1 CHEMBL468595 IC50 17.5 nM
COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cn1 CHEMBL3827281 IC50 17.55 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2Cc2ccc(F)cc2)c1)NO CHEMBL487106 IC50 17.6 nM
CC/C=C\CCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830536 Ki 18.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccccc3)nn2)c1)NO CHEMBL483693 IC50 18.5 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCC1)NO CHEMBL491316 Ki 18.9 nM
CCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830537 Ki 19.0 nM
O=C(CCCCCCn1cc(-c2ncnc3[nH]ccc23)cn1)NO CHEMBL4060201 IC50 19.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2Cc2ccccc2)c1)NO CHEMBL488747 IC50 19.2 nM
CN(C)CCc1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL3907295 pIC50 19.95 nM
CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O CHEMBL402363 Ki 20.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCC(=O)NO)OC1=O CHEMBL4099942 IC50 21.0 nM
CN(C)CC(C)(C)Cn1c(CCc2ccccc2)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL460963 Ki 23.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCCC1)NO CHEMBL489332 Ki 23.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL3215861 Ki 23.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL1851943 Ki 23.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2-c2ccccc2)c1)NO CHEMBL520056 IC50 24.5 nM
O=C(CCCCc1ccn(Cc2ccc(Nc3ccccc3)cc2)n1)NO CHEMBL3335299 IC50 25.0 nM
Cn1cncc1-c1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL4541796 pIC50 25.12 nM
C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL598797 IC50 26.1 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 IC50 27.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccccc3)nn2)c1)NO CHEMBL519668 IC50 27.7 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830420 Ki 28.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)c1 CHEMBL469274 IC50 28.2 nM
N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL389688 IC50 28.3 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830422 Ki 29.0 nM
O=C(CCCCc1ccn(Cc2ccc(-c3ccccc3)cc2)n1)NO CHEMBL3335300 IC50 29.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3098604 IC50 30.0 nM
CC(CCCCCC(=O)NO)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL4095596 IC50 31.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 IC50 31.0 nM
O=C1CCC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356524 IC50 32.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(F)cc3)nn2)c1)NO CHEMBL1091474 IC50 32.8 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830396 Ki 34.0 nM
CN(C)CC(C)(C)Cn1c(CC(C)(C)C)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL1830397 Ki 34.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccc(F)cc3)nn2)c1)NO CHEMBL483892 IC50 34.3 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)Nc3ccccn3)cc2)cc1 CHEMBL3670669 IC50 35.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cn(-c3ccccc3)nn2)cc1)NO CHEMBL519491 IC50 36.1 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSC(=O)CCCCCCC)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622730 IC50 37.0 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622729 IC50 37.4 nM
O=C(CCCCCNC(=O)NC(=O)c1ccccc1)NO CHEMBL1083439 Ki 40.0 nM
O=C1CC[C@H](C(=O)N[C@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356920 IC50 40.0 nM
O=C(CCCCSc1nc(-c2ccc(-c3ccccc3)cc2)cc(=O)[nH]1)NO CHEMBL3426803 IC50 40.0 nM
CC(/C=C/C(=O)NO)=C\[C@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL164868 IC50 40.0 nM
O=C(/C=C/c1ccc(/C=C(/CNC2CC2)c2ccc(F)cc2)cc1)NO CHEMBL3758457 IC50 42.0 nM
N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL227170 IC50 42.1 nM
O=C(NO)c1cnc(N2CCN(C(/C=C/c3ccc(F)cc3)CO)CC2)nc1 CHEMBL594544 IC50 42.6 nM
Nc1ccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)cc1 CHEMBL467793 IC50 44.9 nM
N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL389687 IC50 46.1 nM
Nc1ccccc1NC(=O)CCCCCCC(=O)NO CHEMBL4282111 IC50 49.3 nM
Cn1cc(/C=C/C(=O)NO)cc1C(=O)c1ccccc1 CHEMBL29814 IC50 50.0 nM
CC(Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)C12CC3CC(CC(C3)C1)C2 CHEMBL4244764 Ki 50.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cnnn2CCCCCC(=O)NO)c1 CHEMBL2408778 IC50 51.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098689 IC50 51.0 nM
O=C(/C=C/c1cccn(CCCc2ccc3ccccc3c2)c1=O)NO CHEMBL4082995 IC50 51.6 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cnnn2-c2ccccc2)cc1)NO CHEMBL487742 IC50 55.7 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631914 IC50 62.5 nM
O=C(NO)c1ccc(Cn2ccc3ccccc32)cc1 CHEMBL3958794 pIC50 63.1 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cnnn2Cc2ccc(F)cc2)cc1)NO CHEMBL487741 IC50 64.7 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2ccccc2NC(=O)[C@@H]2CCCN2)cc1)NO CHEMBL2417781 IC50 70.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cnnn2Cc2ccccc2)cc1)NO CHEMBL519746 IC50 70.1 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631913 IC50 70.7 nM
O=C(/C=C/c1ccc(NC(=O)Cc2cccc3ccccc23)cn1)NO CHEMBL4550522 IC50 71.0 nM
Cn1c(CCCC(=O)O)nc2cc(N(CCCl)CCCl)ccc21 CHEMBL487253 IC50 72.0 nM
CC(=O)Nc1ccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)cc1 CHEMBL468842 IC50 73.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4ccc(CNC(=O)CC(=O)NO)cc4)ncc3F)cc2n1C(C)C CHEMBL5220945 IC50 73.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cnnn2CC(O)c2cccc(Br)c2)cc1)NO CHEMBL487943 IC50 74.8 nM
Nc1ccc(F)cc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1 CHEMBL4087968 IC50 78.0 nM
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1 CHEMBL3621988 IC50 78.0 nM
COc1cc(OC)c2c(N3CCS(=O)(=O)CC3)nc(-c3cc(C)c(OCCCCCC(=O)NO)c(C)c3)nc2c1 CHEMBL4790998 IC50 78.24 nM
O=C(NO)c1ccc(CC(=O)N(CCO)c2ccccc2)cc1 CHEMBL4066043 pIC50 79.43 nM
O=C(NO)c1ccc(Cn2cc(CCO)c3ccccc32)cc1 CHEMBL4466930 pIC50 79.43 nM
O=C(CCCCCCOc1ccc2cc1COC/C=C/COCc1cccc(c1)-c1ccnc(n1)N2)NO CHEMBL3917405 IC50 80.0 nM
Cc1cccc(CCNC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356937 IC50 81.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cn(CC(O)c3cccc(Br)c3)nn2)cc1)NO CHEMBL483495 IC50 86.5 nM
O=C(CCCCC[C@H](NC(=O)C1C(=O)NCC1c1ccccc1)C(=O)Nc1ccccc1)NO CHEMBL3098694 IC50 88.0 nM
CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)cc1 CHEMBL511749 IC50 90.7 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098690 IC50 93.0 nM
O=C(CCCCc1ccn(Cc2cccc(-c3ccccc3)c2)n1)NO CHEMBL3335283 IC50 94.0 nM
CCCCN(Cc1ccc(C(=O)NO)cc1)C(=O)Nc1ccccc1 CHEMBL2179618 pIC50 100.0 nM
Cc1ccc(CN2CCC(c3noc(CN(C)c4ncc(C(=O)NO)cn4)n3)CC2)cc1 CHEMBL4517151 IC50 102.0 nM
O=C1CN(Cc2ccc(C(=O)NO)cc2)C(=O)[C@@H](Cc2c[nH]c3ccccc23)N1 CHEMBL5268638 IC50 105.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cn(Cc3ccc(F)cc3)nn2)cc1)NO CHEMBL483494 IC50 112.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098695 IC50 113.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098691 IC50 113.0 nM
O=C(CCC1C(=O)N(c2ccc(Cl)cc2)C(=O)N1Cc1ccccc1)Nc1ccc(C(=O)NO)cc1 CHEMBL4450285 IC50 114.0 nM
CN1C(=O)CC[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356921 IC50 116.0 nM
Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5433552 IC50 116.1 nM
O=C(CCCCCCNC(=O)c1cnc(N(c2ccccc2)c2ccccc2)nc1)NO CHEMBL2364628 pIC50 125.89 nM
COCCc1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL4445881 pIC50 125.89 nM
O=C(CCCCCCN(c1ccccn1)c1ccc2ccccc2n1)NO CHEMBL3675758 IC50 126.0 nM
Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)c(F)c2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5395502 IC50 127.3 nM
O=C(CCCCc1ccn(Cc2ccc(-n3ccc4ccccc43)cc2)n1)NO CHEMBL3335298 IC50 136.0 nM
C/C=C1\NC(=O)c2csc(n2)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622727 IC50 138.0 nM
[N-]=[N+]=NCc1cc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc(N=[N+]=[N-])c1 CHEMBL1914708 IC50 140.0 nM
CCN(CC)C(=S)SSCCCCCC(=O)Nc1ccccc1 CHEMBL5407807 IC50 140.0 nM
O=C(CCCCC[C@H](NC(=O)C1CCNC1=O)C(=O)Nc1ccccc1)NO CHEMBL3098693 IC50 147.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H](C)NC(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2cccc3ccccc23)NC1=O CHEMBL2012815 IC50 150.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631915 IC50 152.0 nM
O=C(CCCCOCc1cc(-c2ccccc2)on1)NO CHEMBL513160 IC50 155.0 nM
CC(C)(C)OC(=O)NCc1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL4534503 pIC50 158.49 nM
CN1CCc2c(n(Cc3ccc(C(=O)NO)cc3)c3ccccc23)C1 CHEMBL2018451 pIC50 158.49 nM
Cc1ccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)cc1 CHEMBL3098606 IC50 163.0 nM
Cc1ccc(CN2C(=O)N(c3ccc(Cl)cc3)C(=O)C2CCC(=O)Nc2ccc(C(=O)NO)cc2)cc1 CHEMBL4445862 IC50 164.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(=O)O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O CHEMBL3352995 Ki 170.0 nM
O=C(CCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NO CHEMBL227118 IC50 173.0 nM
CN(C)c1ccc(NC(=O)NCCCCCCC(=O)NO)cc1 CHEMBL227120 IC50 176.0 nM
CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1 CHEMBL227119 IC50 178.0 nM
COc1ccc(COC(CCCCCC(=O)NO)C(=O)Nc2ccccc2)cc1 CHEMBL251011 IC50 179.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cn(Cc3ccccc3)nn2)cc1)NO CHEMBL487533 IC50 188.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)NC2CCCC2)N1 CHEMBL3356931 IC50 189.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631917 IC50 190.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631918 IC50 200.0 nM
CC(=O)N1c2ccc(-c3ccc(NC(=O)CCCCCCC(=O)NO)cc3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C CHEMBL3220922 Kd(app) 207.0 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)NCCc1ccccc1)NO CHEMBL3098688 IC50 210.0 nM
O=C(NCC1(c2nc(-c3ccccc3)cs2)CCOCC1)c1cccc(-c2noc(C(F)(F)F)n2)c1 CHEMBL3110004 IC50 210.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCCc1ccccc1)NO CHEMBL3098687 IC50 227.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O CHEMBL3352997 Ki 230.0 nM
O=C(NO)c1ccc(Cn2ccc3cc(C(=O)NCC45C[C@H]6C[C@@H](C4)C[C@@H](C5)C6)ccc32)c(F)c1 CHEMBL5430740 IC50 230.0 nM
COc1cccc2c(C(CCCCCC(=O)NO)c3c[nH]c4c(OC)cccc34)c[nH]c12 CHEMBL561483 IC50 240.0 nM
O=C(CCCCC[C@H](NC(=O)C1CCCNC1=O)C(=O)Nc1ccccc1)NO CHEMBL3098692 IC50 244.0 nM
CN(C)CCOc1ccc(-c2cc(=O)c3c(O)cc(OCCCCCC(=O)NO)cc3o2)cc1 CHEMBL4798571 IC50 246.53 nM
Nc1cccc(-c2csc(NC(=O)CCCCc3cc(C(=O)NO)no3)n2)c1 CHEMBL511432 IC50 250.0 nM
O=C(CCCCCC(c1c[nH]c2ccc([N+](=O)[O-])cc12)c1c[nH]c2ccc([N+](=O)[O-])cc12)NO CHEMBL561604 IC50 250.0 nM
O=C(CCCCCCCS)Nc1ccccc1 CHEMBL326433 IC50 252.0 nM
O=C(CCCCc1cc(C(=O)NO)no1)Nc1nc(-c2ccccc2)cs1 CHEMBL469134 IC50 254.0 nM
O=C(CCC1C(=O)N(c2ccc(Cl)cc2)C(=O)N1Cc1ccc(Br)cc1)Nc1ccc(C(=O)NO)cc1 CHEMBL4444176 IC50 268.0 nM
O=C(NO)c1ccc(CN2CCCc3cccnc32)c(F)c1 CHEMBL5401750 IC50 269.0 nM
O=C(CCCCCCS)Nc1ccccc1 CHEMBL325676 IC50 270.0 nM
Cn1c(/C=C/C(=O)NO)ccc1C(=O)c1ccccc1 CHEMBL29362 IC50 280.0 nM
COc1ccc(-c2cc(-c3ccoc3)c(C(=O)NCc3ccc(C(=O)NO)cc3)[nH]2)cc1 CHEMBL4087897 IC50 290.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccsc3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670674 IC50 294.0 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 IC50 300.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352994 Ki 300.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352823 Ki 300.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)NCc2ccc(C(F)(F)F)cc2)N1 CHEMBL3356933 IC50 310.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)NCCS)cc2)cc1 CHEMBL3670668 IC50 316.0 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)CSCC3)cc1 CHEMBL4438279 pIC50 316.23 nM
Cc1c(C)n(Cc2ccc(C(=O)NO)cc2)c2ccccc12 CHEMBL3971436 pIC50 316.23 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OCCC2 CHEMBL1631916 IC50 320.0 nM
CCCNc1ccc2c3c(cccc13)C(=O)N(CCCCCC(=O)NO)C2=O CHEMBL4475116 IC50 320.0 nM
Nc1ccccc1NC(=O)c1ccc(NC(=O)C(Cc2ccccc2)c2ccccc2)cn1 CHEMBL5409567 IC50 320.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 IC50 331.0 nM
O=C(CCCCCCC(=O)Nc1ccc([C@H]2O[C@@H](CSc3nc(-c4ccccc4)c(-c4ccccc4)o3)C[C@@H](c3ccc(CO)cc3)O2)cc1)NO CHEMBL356769 Ki 373.7 nM
O=C(CCCCCCC(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL1089495 IC50 374.0 nM
C#CCN(C)Cc1cccc(NC(=O)CCCCCCC(=O)NO)c1 CHEMBL5171489 IC50 374.0 nM
COc1ccc2c3c(cccc13)C(=O)N(Cc1ccc(C(=O)NO)cc1)C2=O CHEMBL5195946 IC50 375.0 nM
C/C=C1\NC(=O)c2csc(n2)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCSC(=O)CCCCCCC)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622728 IC50 395.0 nM
Nc1ccc(-c2cc(C(=O)NCCCCC(=O)NO)no2)cc1 CHEMBL468841 IC50 401.0 nM
CN(C)c1cccc2c(S(=O)(=O)NCCCCCC(=O)NO)cccc12 CHEMBL4759256 IC50 420.0 nM
CN(C)c1cccc2c(SNCCCCCC(=O)NO)cccc12 CHEMBL5271192 IC50 420.0 nM
Nc1ccccc1NC(=O)c1ccc(NC(=O)Cc2ccc3ccccc3c2)cn1 CHEMBL5417858 IC50 446.0 nM
CN1C(=O)C2CN(Cc3c2c2ccccc2n3Cc2ccc(C(=O)NO)cc2)C1=O CHEMBL4087616 Ki 452.0 nM
O=C(CCCCc1cc(C(=O)NO)no1)Nc1cnc2ccccc2c1 CHEMBL511715 IC50 471.0 nM
O=C(NO)c1ccc(Cn2nnc(-c3ncccn3)n2)cc1 CHEMBL4453121 IC50 474.0 nM
CC(=O)N1CCc2c(c3ccccc3n2Cc2ccc(C(=O)NO)cc2)C1 CHEMBL4562244 pIC50 501.19 nM
Cc1cccc(NC(=O)CCCCCCC(=O)NO)c1 CHEMBL3098603 IC50 503.0 nM
O=C(NO)c1ccc(CN(Cc2cccnc2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1 CHEMBL5075135 IC50 572.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](/C=C/CCCC(=O)O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O CHEMBL3352992 Ki 600.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(F)c2)c1 CHEMBL5436104 IC50 600.0 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)COCC3)cc1 CHEMBL4531802 pIC50 630.96 nM
Nc1ccccc1NC(=O)c1ccc(CCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 CHEMBL5076343 IC50 632.0 nM
Cc1ccc(NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL3098605 IC50 649.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)NCc2cccc(OCc3ccccc3)c2)N1 CHEMBL3356935 IC50 658.0 nM
O=C(CCCCCN1C(=O)c2cccc3c(NCc4ccccc4)ccc(c23)C1=O)NO CHEMBL4532304 IC50 660.0 nM
O=C(NO)c1ccc(CC(=O)N(CCO)C(=O)Cc2ccccc2)cc1 CHEMBL5194437 IC50 677.0 nM
O=C(CCCCCC1OCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631911 IC50 683.0 nM
CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)NCCCCC(=O)NO)no2)cc1 CHEMBL467792 IC50 690.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](/C=C/CCCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352991 Ki 700.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352996 Ki 700.0 nM
O=C(NO)c1ccc(CN(CCO)C(=O)Cc2ccccc2)cc1 CHEMBL4079541 IC50 700.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccc(O)cc3)cc2-c2ccoc2)cc1 CHEMBL3670675 IC50 723.0 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSC(C)=O)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622731 IC50 751.0 nM
O=C(CCCCc1ccn(-c2ccccc2)n1)NO CHEMBL3335288 IC50 774.0 nM
[N-]=[N+]=NCc1cc(N=[N+]=[N-])cc(C(=O)Nc2ccc(-c3cc(C(=O)NCCCCCCC(=O)NO)no3)cc2)c1 CHEMBL1914702 IC50 776.0 nM
Nc1cccc(-c2cc(C(=O)NCCCCC(=O)NO)no2)c1 CHEMBL446512 IC50 840.0 nM
O=C(CCCCNC(=O)c1cc(-c2ccccc2)on1)NO CHEMBL467998 IC50 852.0 nM
O=C(CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12)NO CHEMBL564876 IC50 870.0 nM
CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NCCCCCCC(=O)NO)c3C2)c(O)cc1O CHEMBL3233755 IC50 886.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2cc(C(=O)NCCCCC(=O)NO)no2)c1 CHEMBL469275 IC50 891.0 nM
CC(C)(C)c1ccc(C(=O)Nc2ccc(C(=O)NO)cc2)cc1 CHEMBL4452620 IC50 899.0 nM
Cc1cc(-c2nc3sc4c(c3c(=O)[nH]2)CCN(C)C4)cc(C)c1OCCCCCC(=O)NO CHEMBL4514808 IC50 923.0 nM
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C2\NC(=O)c3ccccc32)cc1 CHEMBL4561073 IC50 950.0 nM
O=C(CCCCCC1OCCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631912 IC50 958.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352993 Ki 1000.0 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)CCCC3)cc1 CHEMBL4475240 pIC50 1000.0 nM