Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 Ki 0.07 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCC/C=C/[C@@H]2CC(=O)NCc3nc(cs3)C3=N[C@@](C)(CS3)C(=O)N[C@@H](C(C)C)C(=O)O2)OC1=O CHEMBL3329621 IC50 0.1 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)OC1=O CHEMBL3329622 IC50 0.2 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL343448 IC50 0.3 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3310505 IC50 0.3 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356916 IC50 1.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1nc2cc(C(F)(F)F)ccc2o1 CHEMBL4130288 IC50 1.0 nM
Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 IC50 1.6 nM
O=C(NO)c1cccc2c1CN(c1nc3ccc(C(F)(F)F)cc3[nH]1)C2 CHEMBL4127743 IC50 2.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1nc2ccc(C(F)(F)F)cc2[nH]1 CHEMBL4127020 IC50 2.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1nc2ncccc2o1 CHEMBL4128972 IC50 2.0 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 2.1 nM
Cc1ccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)cc1 CHEMBL3356917 IC50 3.0 nM
CC(C)[C@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL1796689 IC50 3.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1ccc(C(F)(F)F)nc1 CHEMBL4127735 IC50 3.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1cnc(C(F)(F)F)cn1 CHEMBL4126661 IC50 3.0 nM
O=C1NC[C@@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356925 IC50 4.0 nM
CCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830537 Ki 4.2 nM
CN1C(=O)CCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356526 IC50 5.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3356923 IC50 5.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1ncc(C(F)(F)F)cn1 CHEMBL4127894 IC50 5.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 5.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ccc(C(=O)NO)cc4)cc3n2)cn1 CHEMBL5278968 IC50 5.4 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 IC50 5.58 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356523 IC50 6.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1ccc(C(F)(F)F)cn1 CHEMBL4129134 IC50 6.0 nM
O=C(NO)c1cccc2c1CN(c1nc3ccccc3o1)C2 CHEMBL4129266 IC50 7.0 nM
O=C(NO)c1cccc2c1CN(c1ccc(C(F)(F)F)cn1)C2 CHEMBL4129143 IC50 7.0 nM
CC/C=C\CCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830536 Ki 8.8 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 9.0 nM
O=C1NCCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356527 IC50 9.0 nM
O=C1CCC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356524 IC50 10.0 nM
O=C1C[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356929 IC50 10.0 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 IC50 10.0 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 IC50 10.6 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(C)C CHEMBL1830424 Ki 11.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2C)c1 CHEMBL3356924 IC50 12.0 nM
O=C1NC[C@H](c2ccccc2)[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356926 IC50 12.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCC1)NO CHEMBL491316 Ki 12.8 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830420 Ki 13.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098691 IC50 13.0 nM
O=C1NC[C@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356927 IC50 13.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(Br)c2)c1 CHEMBL5399941 IC50 13.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCCC1)NO CHEMBL489332 Ki 14.0 nM
CN(C)CC(C)(C)Cn1c(CC(C)(C)C)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL1830397 Ki 14.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830422 Ki 14.0 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3353925 IC50 14.0 nM
O=C1CC[C@@H](C(=O)N[C@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356919 IC50 14.0 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 IC50 14.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3098604 IC50 15.0 nM
O=C1NCCC[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356915 IC50 15.0 nM
O=C(/C=C/c1ccc(C(=O)NO)cc1)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(Cl)cc1 CHEMBL4229142 IC50 15.8 nM
CN(C)CC(C)(C)Cn1c(CCc2ccccc2)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL460963 Ki 16.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830396 Ki 18.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCCN2C1=O CHEMBL5413269 Ki 18.0 nM
O=C(NO)c1cnc(N2CCN(C(/C=C/c3ccc(F)cc3)CO)CC2)nc1 CHEMBL594544 IC50 20.7 nM
CC(C)(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4241370 Ki 21.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631914 IC50 22.9 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL3215861 Ki 24.0 nM
O=C1NC[C@@H](c2ccccc2)[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356928 IC50 24.0 nM
O=C(NO)c1cccc2c1CN(c1ccc3ccccc3n1)C2 CHEMBL4129231 IC50 26.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 Ki 27.0 nM
CC1(C)c2cccc(C(=O)NO)c2CN1c1cnc(C(F)(F)F)nc1 CHEMBL4126502 IC50 27.0 nM
O=C1CC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356918 IC50 30.0 nM
O=C(NO)c1cccc2c1CCN(c1nc3ccccc3[nH]1)CC2 CHEMBL4129070 IC50 30.0 nM
O=C(CCCCCCn1cc(-c2ncnc3[nH]ccc23)cn1)NO CHEMBL4060201 IC50 31.0 nM
O=C(CCCCCCc1nc2ccc(Br)cc2[nH]1)NO CHEMBL2414098 IC50 33.4 nM
CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL257972 Ki 35.0 nM
O=C(NO)c1cccc2c1CN(c1nc3ccccc3s1)C2 CHEMBL4125954 IC50 35.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098695 IC50 37.0 nM
CC(Nc1c(NCCCCCC(=O)NO)c(=O)c1=O)C12CC3CC(CC(C3)C1)C2 CHEMBL4244764 Ki 38.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccccc1)NO CHEMBL1083439 Ki 39.0 nM
CCCCCCNNC(=O)c1cnc(N2CCN(Cc3c[nH]c4ccccc34)CC2)nc1 CHEMBL5195676 IC50 41.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL1851943 Ki 43.0 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2cccc(C(F)(F)F)c2)N1 CHEMBL3353927 IC50 44.0 nM
CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(C(=O)NO)cc2)cc1 CHEMBL4798826 IC50 44.2 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098689 IC50 47.0 nM
O=C(NO)c1ccc(CN(C2CC2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL5193507 IC50 47.0 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)NCCc1ccccc1)NO CHEMBL3098688 IC50 47.8 nM
O=C(NO)c1ccc(N(Cc2ccccc2)C(=O)CN(Cc2c(F)c(F)c(F)c(F)c2F)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL4563224 IC50 51.9 nM
COc1ccccc1C(=O)N[C@H](COc1cccc(/C=C/C(=O)NO)c1)Cc1c[nH]c2ccccc12 CHEMBL3354920 IC50 52.7 nM
O=C(/C=C/c1cccn(CCCc2ccc3ccccc3c2)c1=O)NO CHEMBL4082995 IC50 54.7 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL3098602 IC50 55.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631913 IC50 57.7 nM
CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O CHEMBL402363 Ki 60.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCC(=O)N2)c1 CHEMBL3356922 IC50 62.0 nM
CN1C(=O)CC[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356921 IC50 67.0 nM
O=C(CCCCC[C@H](NC(=O)C1C(=O)NCC1c1ccccc1)C(=O)Nc1ccccc1)NO CHEMBL3098694 IC50 70.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)Nc3ccccn3)cc2)cc1 CHEMBL3670669 IC50 72.0 nM
Cc1ccc(CN(Cc2ccc(C(=O)NO)cc2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL5075515 IC50 73.0 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098690 IC50 75.0 nM
O=C(CCCCCCC(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL1089495 IC50 75.1 nM
O=C(/C=C/c1ccc(C(=O)NO)cc1)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1cccc(Cl)c1 CHEMBL4225063 IC50 76.3 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccccc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4460552 IC50 77.82 nM
Cc1ccc(NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL3098605 IC50 78.6 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(F)c2)c1 CHEMBL5436104 IC50 79.0 nM
CCCNc1ccc2c3c(cccc13)C(=O)N(CCCCCC(=O)NO)C2=O CHEMBL4475116 IC50 80.0 nM
Cc1cccc(CCNC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356937 IC50 82.0 nM
O=C(NO)c1ccc(Cn2ccc3cc(C(=O)NCC45C[C@H]6C[C@@H](C4)C[C@@H](C5)C6)ccc32)c(F)c1 CHEMBL5430740 IC50 87.0 nM
CC(C)(C)c1ccc(CN(Cc2ccc(C(=O)NO)cc2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL5085755 IC50 88.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)NC2CCCC2)N1 CHEMBL3356931 IC50 89.0 nM
COc1cc(C(=O)NO)ccc1Cn1ccc2cc(C(=O)NCC34C[C@H]5C[C@@H](C3)C[C@@H](C4)C5)ccc21 CHEMBL5405871 IC50 93.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631915 IC50 97.1 nM
O=C(CCCCSc1nc(-c2ccc(-c3ccccc3)cc2)cc(=O)[nH]1)NO CHEMBL3426803 IC50 100.0 nM
O=C1CC[C@H](C(=O)N[C@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356920 IC50 102.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631917 IC50 103.0 nM
O=C(CCCCCCNc1nc2ccccc2nc1-c1nc2ccccc2o1)NO CHEMBL5269112 IC50 109.62 nM
COc1cc(Cn2ccc3cc(C(=O)NCC45C[C@H]6C[C@@H](C4)C[C@@H](C5)C6)ccc32)ccc1C(=O)NO CHEMBL5415287 IC50 110.0 nM
O=C(CCCCCCN(c1ccccn1)c1ccc2ccccc2n1)NO CHEMBL3675758 IC50 112.0 nM
O=C(NO)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1 CHEMBL5092466 IC50 115.0 nM
[N-]=[N+]=NCc1cc(N=[N+]=[N-])cc(C(=O)Nc2ccc(-c3cc(C(=O)NCCCCCCC(=O)NO)no3)cc2)c1 CHEMBL1914702 IC50 116.0 nM
O=C(NO)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL5080426 IC50 122.0 nM
Cc1ccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)cc1 CHEMBL3098606 IC50 127.0 nM
O=C(CCCCCCNc1nn2c(=O)c3ccccc3nc2c2ccccc12)NO CHEMBL5087773 IC50 130.0 nM
O=C(CCCCCCCNc1nn2c(=O)c3ccccc3nc2c2ccccc12)NO CHEMBL5084865 IC50 130.0 nM
O=C(CCCCCCCS)Nc1ccccc1 CHEMBL326433 IC50 133.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)NCc2ccc(C(F)(F)F)cc2)N1 CHEMBL3356933 IC50 140.0 nM
COc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4237803 Ki 140.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(Cl)c2)c1 CHEMBL5415658 IC50 140.0 nM
O=C(CCCCC[C@H](NC(=O)C1CCNC1=O)C(=O)Nc1ccccc1)NO CHEMBL3098693 IC50 150.0 nM
O=C(CCCCCN1C(=O)c2cccc3c(NCc4ccccc4)ccc(c23)C1=O)NO CHEMBL4532304 IC50 150.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(O)c2)c1 CHEMBL5395395 IC50 160.0 nM
O=C(/C=C/c1cccn(CCc2ccc3ccccc3c2)c1=O)NO CHEMBL4577107 IC50 160.87 nM
O=C(NO)c1cccc2c1CN(c1nc3ccccc3[nH]1)C2 CHEMBL4127193 IC50 170.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631918 IC50 174.0 nM
O=C(/C=C/c1ccc(C(=O)NO)cc1)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(Br)cc1 CHEMBL4228565 IC50 175.9 nM
CN(C)CCOc1ccc(-c2cc(=O)c3c(O)cc(OCCCCCC(=O)NO)cc3o2)cc1 CHEMBL4798571 IC50 179.35 nM
CCCCCCNNC(=O)c1ccc(-c2ccc(CNC(C)=O)cc2)cc1 CHEMBL5174998 IC50 180.0 nM
O=C(CCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NO CHEMBL227118 IC50 190.0 nM
O=C(CCCCCN1C(=O)c2cccc3c(Nc4ccccc4)ccc(c23)C1=O)NO CHEMBL4526647 IC50 190.0 nM
O=C(NO)c1ccc(N(Cc2ccc(C(F)(F)F)cc2)C(=O)CN(Cc2c(F)c(F)c(F)c(F)c2F)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL4563091 IC50 191.0 nM
COc1ccc(COC(CCCCCC(=O)NO)C(=O)Nc2ccccc2)cc1 CHEMBL251011 IC50 197.0 nM
O=C(CCCCCN1C(=O)c2cccc3c(Nc4cccc(F)c4)ccc(c23)C1=O)NO CHEMBL4461622 IC50 210.0 nM
CC(C)(C)c1ccc(NS(=O)(=O)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4760053 IC50 223.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cnnn2CCCCCC(=O)NO)c1 CHEMBL2408778 IC50 224.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OCCC2 CHEMBL1631916 IC50 226.0 nM
O=C(NO)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1 CHEMBL5070393 IC50 235.0 nM
CN(Cc1ccc(C(=O)NO)cc1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F CHEMBL5198759 IC50 246.0 nM
CCOc1cc(Cn2ccc3cc(C(=O)NCC45C[C@H]6C[C@@H](C4)C[C@@H](C5)C6)ccc32)ccc1C(=O)NO CHEMBL5421030 IC50 250.0 nM
CC(C)(C)c1ccc(CN(C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4546897 IC50 253.0 nM
CC(C)(C)c1ccc(CN(C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)c(F)c2)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4534860 IC50 254.0 nM
O=C(CCCCC[C@H](NC(=O)C1CCCNC1=O)C(=O)Nc1ccccc1)NO CHEMBL3098692 IC50 255.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NCCc1ccccc1)NO CHEMBL3098687 IC50 262.0 nM
O=C(CCCCCCS)Nc1ccccc1 CHEMBL325676 IC50 262.0 nM
O=C(NO)c1ccc(CN(Cc2ccccc2F)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1 CHEMBL5094501 IC50 263.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 IC50 287.0 nM
CC(C)(C)c1ccc(CN(C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)cc2F)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4580317 IC50 288.0 nM
O=C(CCCCCN1C(=O)c2cccc3c(N4CCOCC4)ccc(c23)C1=O)NO CHEMBL4160632 IC50 290.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)NCc2cccc(OCc3ccccc3)c2)N1 CHEMBL3356935 IC50 293.0 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)N2CCc3ccccc3C2)N1 CHEMBL3356939 IC50 293.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H](C)NC(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2cccc3ccccc23)NC1=O CHEMBL2012815 IC50 300.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(=O)O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O CHEMBL3352995 Ki 300.0 nM
O=C(NO)c1cccc2c1CN(C1=NC3CCCCC3N1)C2 CHEMBL4125788 IC50 300.0 nM
O=C(NO)c1ccc(N(Cc2ccc(C(F)(F)F)cc2)C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL4561439 IC50 304.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)NCCS)cc2)cc1 CHEMBL3670668 IC50 319.0 nM
CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(NCc3ccc(C(=O)NO)cc3)c2c(=O)n1-c1ccccc1 CHEMBL4516095 IC50 324.0 nM
COc1ccc(-c2cc(-c3ccoc3)c(C(=O)NCc3ccc(C(=O)NO)cc3)[nH]2)cc1 CHEMBL4087897 IC50 340.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccsc3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670674 IC50 341.0 nM
O=C(NO)c1ccc(N(Cc2ccc(C(F)(F)F)cc2)C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)cc2F)cc1 CHEMBL4447317 IC50 346.0 nM
Cc1cc(Cn2ccc3cc(C(=O)NCC45C[C@H]6C[C@@H](C4)C[C@@H](C5)C6)ccc32)ccc1C(=O)NO CHEMBL5415394 IC50 350.0 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 IC50 360.0 nM
O=C(NO)c1ccc(CN(C2CC2)S(=O)(=O)c2c(F)c(Cl)c(F)c(Cl)c2F)cc1 CHEMBL5192119 IC50 364.0 nM
O=C(NO)c1ccc(CNc2cccc3cccnc23)cc1 CHEMBL4104117 IC50 376.0 nM
O=C(NO)c1ccc(N(Cc2ccc(C(F)(F)F)cc2)C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)c(F)c2)cc1 CHEMBL4578694 IC50 396.0 nM
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1 CHEMBL3621988 IC50 400.0 nM
O=C(/C=C/c1ccc(C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1)NO CHEMBL564382 IC50 410.0 nM
O=C(NO)c1ccc(NC(=O)c2ccc(C3CCCCC3)cc2)cc1 CHEMBL4790223 IC50 411.0 nM
O=C(CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12)NO CHEMBL564876 IC50 430.0 nM
Nc1ccc(F)cc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1 CHEMBL4087968 IC50 432.0 nM
CC(C)(C)c1ccc(NC(=O)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4742241 IC50 447.0 nM
O=C(NO)c1ccc(CN(Cc2ccncc2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1 CHEMBL5089527 IC50 472.0 nM
[N-]=[N+]=NCc1cc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc(N=[N+]=[N-])c1 CHEMBL1914708 IC50 476.0 nM
O=C(NO)c1ccc(Cn2ccc3cc(C(=O)NCC45C[C@H]6C[C@@H](C4)C[C@@H](C5)C6)ccc32)cc1 CHEMBL5424224 IC50 480.0 nM
COc1ccc(Cn2ccc3ccc(C(=O)NO)cc32)cc1 CHEMBL2170177 IC50 482.0 nM
CN1C(=O)C2CN(Cc3c2c2ccccc2n3Cc2ccc(C(=O)NO)cc2)C1=O CHEMBL4087616 Ki 495.0 nM
O=C(NO)c1ccc(Cn2c3c(c4cc(F)ccc42)C[S+]([O-])CC3)cc1 CHEMBL4283105 IC50 500.0 nM
CN(C)c1cccc2c(SNCCCCCC(=O)NO)cccc12 CHEMBL5271192 IC50 520.0 nM
CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NCCCCCCC(=O)NO)c3C2)c(O)cc1O CHEMBL3233755 IC50 521.0 nM
O=C(NO)c1ccc(N(Cc2cccc(C(F)(F)F)c2)C(=O)c2cccc(C(F)(F)F)c2)cc1 CHEMBL4641390 IC50 526.0 nM
O=C(NO)c1ccc(CN2c3ccccc3CC[C@@H]3CCCC[C@H]32)cc1 CHEMBL4469098 IC50 540.0 nM
O=C(CCCCCC1OCCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631912 IC50 546.0 nM
O=C(CCCCCC1OCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631911 IC50 564.0 nM
CCCNNC(=O)c1cnc(N2CCN(Cc3c[nH]c4ccccc34)CC2)nc1 CHEMBL5171086 IC50 570.0 nM
Cc1nc(NC(=O)N2C[C@H](NS(=O)(=O)Cc3ccc(C(=O)NO)cc3)C[C@H]2C(N)=O)sc1-c1ccnc(C(C)(C)C(F)(F)F)c1 CHEMBL5439214 IC50 586.0 nM
Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1 CHEMBL272980 IC50 590.0 nM
O=C(CCCCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1)NO CHEMBL3426906 IC50 608.0 nM
O=C(CS)NCCCCCC(=O)Nc1cccc2cccnc12 CHEMBL178456 IC50 610.0 nM
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C2\NC(=O)c3ccccc32)cc1 CHEMBL4561073 IC50 632.0 nM
CC(C)(C)c1ccc(CN(C(=O)CN(Cc2c(F)c(F)c(F)c(F)c2F)S(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4520400 IC50 636.0 nM
COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(Cc3ccc(C(=O)NO)cc3)c2c1 CHEMBL4093691 IC50 651.0 nM
CCc1nc2ccc(Cc3ccc(C(=O)NO)cc3)cc2c(=O)n1CCc1ccccc1 CHEMBL2425970 IC50 656.0 nM
O=C(CCCCCS)Nc1ccccc1 CHEMBL109654 IC50 659.0 nM
CC(C)(C)c1ccc(CN(C(=O)CNS(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)NO)cc2)cc1 CHEMBL4560533 IC50 665.0 nM
CC(C)(C)c1cc(CN(C(=O)c2cccc(C(F)(F)F)c2)c2ccc(C(=O)NO)cc2)cc(C(C)(C)C)c1 CHEMBL4646090 IC50 673.0 nM
CCN(c1ccc(C(=O)NO)cc1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL4643791 IC50 695.0 nM
CN(CC(=O)N(Cc1ccc(C(C)(C)C)cc1)c1ccc(C(=O)NO)cc1)S(=O)(=O)c1ccc(F)cc1 CHEMBL4576056 IC50 697.0 nM
O=C(NO)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL4750701 IC50 700.0 nM
O=C(NO)c1ccc(NC(=O)c2ccc(C3CC3)cc2)cc1 CHEMBL4747455 IC50 704.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccc(O)cc3)cc2-c2ccoc2)cc1 CHEMBL3670675 IC50 718.0 nM
O=C(CCCCCCC(=O)Nc1ccc([C@H]2O[C@@H](CSc3nc(-c4ccccc4)c(-c4ccccc4)o3)C[C@@H](c3ccc(CO)cc3)O2)cc1)NO CHEMBL356769 Ki 718.7 nM
Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5433552 IC50 724.4 nM
O=C(/C=C/c1ccc2c(=O)n(CCc3ccccc3)cnc2c1)NO CHEMBL2425960 IC50 730.0 nM
O=C(NO)c1ccc(Cn2nnc(-c3ncccn3)n2)cc1 CHEMBL4453121 IC50 762.0 nM
O=C(CCCCCCS)NC1CCCC1 CHEMBL3356930 IC50 776.0 nM
O=C(NO)c1ccc(CN(Cc2ccc(F)cc2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL5080599 IC50 787.0 nM
O=C(/C=C/c1ccc(/C=N/OCc2ccc([N+](=O)[O-])cc2)cc1)NO CHEMBL471042 IC50 790.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352823 Ki 800.0 nM
CCN(c1ccc(C(=O)NO)cc1)S(=O)(=O)c1cccc(C(C)(C)C)c1 CHEMBL4640819 IC50 802.0 nM
O=C(NO)c1ccc(Cn2c(=O)[nH]c(=O)c3cccc(Cl)c32)cc1 CHEMBL5438457 IC50 812.0 nM
O=C(NO)c1ccc(CN2c3cc(C(F)(F)F)ccc3CCC[C@@H]3CCCC[C@H]32)cc1 CHEMBL4450128 IC50 820.0 nM
CCCCCCCCCCCCCCCCNNC(=O)c1cccs1 CHEMBL4777961 IC50 830.0 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccncc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827517 IC50 835.0 nM
CC(C)(C)OC(=O)N(Cc1ccc(C(C)(C)C)cc1)c1ccc(C(=O)NO)cc1 CHEMBL4559559 IC50 837.0 nM
Cc1cc(C)cc(C(=O)NOCCCCCC(=O)NO)c1 CHEMBL2312168 IC50 852.0 nM
O=C(CCCCc1ccn(Cc2ccc(-n3ccc4ccccc43)cc2)n1)NO CHEMBL3335298 IC50 897.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC1=O CHEMBL3352997 Ki 900.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL27759 IC50 900.0 nM
O=C(/C=C/c1ccc(OC[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(Cl)cc2)cc1)NO CHEMBL3233698 IC50 900.4 nM
O=C(CCCCCCOc1ccc2cc1COC/C=C/COCc1cccc(c1)-c1ccnc(n1)N2)NO CHEMBL3917405 IC50 930.0 nM
Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)c(F)c2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5395502 IC50 930.9 nM
O=C(NO)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1 CHEMBL5093071 IC50 941.0 nM
CC(C)N(Cc1ccc(C(=O)NO)cc1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F CHEMBL5179295 IC50 941.0 nM
O=C(CCCCCCS)N1CCc2ccccc2C1 CHEMBL3356938 IC50 949.0 nM
Cc1ccc(C(=O)NOCCCCCC(=O)NO)cc1C CHEMBL2312167 IC50 997.0 nM
CC(C)[C@H]1NC(=O)C[C@@H](CCCCCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL3352994 Ki 1000.0 nM