C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3310505 Ki 0.009 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL343448 Ki 0.038 nM
O=c1cc(C2CCCC2)cccc1O CHEMBL2408247 Ki 0.04 nM
O=c1cc(-c2ccccc2)cccc1O CHEMBL2408242 Ki 0.06 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 Ki 0.06 nM
O=C(/C=C/C#Cc1ccc(NS(=O)(=O)c2ccccc2)cc1)NO CHEMBL314389 Ki 0.1 nM
CCOC(=O)NCCCC(=O)NCCc1ccccc1 CHEMBL3086767 IC50 0.112 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL430060 Ki 0.12 nM
COc1ccc(-c2cccc(O)c(=O)c2)cc1 CHEMBL2408243 Ki 0.12 nM
CC(C)(C)c1cccc(O)c(=O)c1 CHEMBL2408245 Ki 0.13 nM
O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)NO CHEMBL99392 Ki 0.13 nM
Cc1[nH]c2ccccc2c1CCNCc1cccc(/C=C/C(=O)NO)c1 CHEMBL4080164 IC50 0.18 nM
CN(CCc1ccccc1)S(=O)(=O)c1cccc(/C=C/C(=O)NO)c1 CHEMBL5274004 IC50 0.2 nM
CCC(C)c1cccc(O)c(=O)c1 CHEMBL2408246 Ki 0.22 nM
COc1ccc(-c2ccccc(O)c2=O)c(OC)c1OC CHEMBL2408241 Ki 0.23 nM
O=c1c(O)ccccc1-c1ccc2ccccc2c1 CHEMBL2408238 Ki 0.25 nM
O=c1c(O)ccccc1-c1ccccc1 CHEMBL2408237 Ki 0.26 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3cccnc3cc2OC)[nH]1 CHEMBL4861467 IC50 0.3 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(c(OC)cc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4878197 IC50 0.31 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCCN2C1=O CHEMBL5413269 Ki 0.35 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)[nH]1 CHEMBL5220926 IC50 0.4 nM
COc1ccc(OC)c(-c2ccccc(O)c2=O)c1 CHEMBL2408240 Ki 0.42 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4860000 IC50 0.43 nM
CN1CC(C(=O)N[C@@H](CCCCCC(=O)c2ccon2)c2ncc(-c3ccccc3F)[nH]2)C1 CHEMBL4641682 IC50 0.47 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCC/C=C/[C@@H]2CC(=O)NCc3nc(cs3)C3=N[C@@](C)(CS3)C(=O)N[C@@H](C(C)C)C(=O)O2)OC1=O CHEMBL3329621 IC50 0.5 nM
COc1ccc(OC)c(-c2cccc(O)c(=O)c2)c1 CHEMBL2408244 Ki 0.51 nM
Cn1ccc2c(CCNS(=O)(=O)c3ccc(/C=C/C(=O)NO)cc3)cccc21 CHEMBL4065026 IC50 0.53 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)[nH]1 CHEMBL5218854 IC50 0.59 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C4CC4)nc3cc2OC)[nH]1 CHEMBL5218537 IC50 0.6 nM
C[C@@H]1CN(C(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cnn(CCCCCCC(=O)NO)c4n3)cc2)CCO1 CHEMBL4532398 IC50 0.61 nM
Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 Ki 0.65 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 Ki 0.65 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4649205 IC50 0.69 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)o1 CHEMBL4862152 IC50 0.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccc(=O)n(C)c3cc2OC)[nH]1 CHEMBL5220969 IC50 0.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2C)[nH]1 CHEMBL5219115 IC50 0.7 nM
Cc1cc(C(=O)CCCCC[C@H](NC(=O)C2CN(C)C2)c2ncc(-c3ccccc3F)[nH]2)no1 CHEMBL4637689 IC50 0.76 nM
O=C(C=C1c2ccccc2-c2ccccc21)NCCCCCC(=O)NO CHEMBL485514 IC50 0.8 nM
CC(=O)Nc1ccc(C(=O)Nc2ccccc2N)cc1 CHEMBL235191 K 0.8 nM
COc1ccc(-c2ccccc(O)c2=O)cc1 CHEMBL2408239 Ki 0.81 nM
CN1CC(C(=O)N[C@@H](CCCCCC(=O)c2ccon2)c2ncc(-c3ccccc3F)o2)C1 CHEMBL4634501 IC50 0.82 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 Ki 0.85 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(C/C=C/CN2C4CCC2c2cc(ccc24)-c2cnc1[nH]2)CC3 CHEMBL4854377 IC50 0.86 nM
CC(C)[C@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL1796689 IC50 0.9 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)OC1=O CHEMBL3329622 IC50 0.9 nM
O=C(/C=C/c1ccc(S(=O)(=O)NCCc2cccc3[nH]ccc23)cc1)NO CHEMBL4069853 IC50 0.9 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593247 IC50 0.9 nM
O=C(CCCCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3759921 IC50 1.0 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1ccc(O)cc1)NC2=O CHEMBL3317811 IC50 1.1 nM
CC(C)(C)OC(=O)n1cnc(C[C@@H]2NC(=O)[C@]3(C)CSC(=N3)c3csc(n3)CNC(=O)C[C@@H](/C=C/CCS)OC2=O)c1 CHEMBL3317818 IC50 1.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3[nH]c4ccccc4c3c2)[nH]1 CHEMBL4780309 IC50 1.1 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL3039527 IC50 1.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(C4CC4)ccc3c2)[nH]1 CHEMBL5218918 IC50 1.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)o1 CHEMBL5218693 IC50 1.1 nM
O=C(CCCCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621294 IC50 1.11 nM
O=C(CCCCCC(=O)N(Cc1ccc(Br)s1)c1ccc(OCCN2CCOCC2)cc1)NO CHEMBL5274330 IC50 1.14 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL27759 IC50 1.2 nM
COc1cc(-c2nc(-c3nnc(CCCCC(=O)NO)o3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL5192364 IC50 1.2 nM
[11CH3]n1cc(CCNCc2ccc(/C=C/C(=O)NO)cc2)c2ccccc21 CHEMBL5288006 IC50 1.2 nM
C[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)NC(=O)[C@@H](C)NC1=O CHEMBL279636 Ki 1.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)o1 CHEMBL5220278 IC50 1.3 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 Ki 1.4 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1c[nH]cn1)NC2=O CHEMBL3317812 IC50 1.4 nM
CC(C)(C)OC(=O)NCCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3317817 IC50 1.4 nM
C/C=C1\NC(=O)[C@@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL146250 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4642518 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637357 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644038 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(C2=CCC(C)N=C2OC)[nH]1 CHEMBL4780974 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3cccnc3cc2OC)[nH]1 CHEMBL5218586 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2F)[nH]1 CHEMBL5220233 IC50 1.4 nM
CC(=O)Nc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL235842 Ki 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc3nc(C)ccc3c2)nc1C#N CHEMBL4759693 IC50 1.5 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 Ki 1.6 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 1.6 nM
Nc1ccc(-c2nc(N3CCOCC3)c3cnn(CCCCCCC(=O)NO)c3n2)cc1 CHEMBL4552057 IC50 1.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(=O)n(C)ccc3c2)[nH]1 CHEMBL4856631 IC50 1.6 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCCCCCC(=O)NO)c4)nc3c2)c1 CHEMBL5177696 IC50 1.6 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1ccccc1)NC2=O CHEMBL3317810 IC50 1.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(-c3cccnc3)cc2)nc1C#N CHEMBL4746782 IC50 1.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCC(N(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4642023 IC50 1.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(Cl)ccc2OC)[nH]1 CHEMBL4753452 IC50 1.8 nM
O=C(NO)c1cnc(N2CCC3(CCN(Cc4c[nH]c5ccccc45)C3)CC2)nc1 CHEMBL4763061 IC50 1.8 nM
Cc1[nH]c2ccccc2c1C1=CCC(NCc2ccc(OCC(=O)NO)cc2F)CC1 CHEMBL5185310 IC50 1.9 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Cc3c[nH]c4ccccc34)CC2)nc1 CHEMBL3891420 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638264 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C)ccc2OC)[nH]1 CHEMBL4792257 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(N4CCCC4)nc3cc2OC)[nH]1 CHEMBL4861271 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(N4CCCC4)ccc3c2)[nH]1 CHEMBL5220616 IC50 2.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccn(CC)c(=O)c3cc2OC)o1 CHEMBL5218767 IC50 2.0 nM
C#CCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL1771484 IC50 2.1 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3759982 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc3nn(C)cc3c2)nc1C#N CHEMBL4761973 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(-c4ncco4)ccc3c2)[nH]1 CHEMBL5219359 IC50 2.1 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 Ki 2.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cccnc3cc2OC)o1 CHEMBL4873493 IC50 2.2 nM
O=C(CCCCc1nnc(-c2cc3c([nH]c4ccccc43)c(-c3ccc(C(F)(F)F)cc3)n2)o1)NO CHEMBL5187023 IC50 2.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(OC)ccc3c2)[nH]1 CHEMBL5219634 IC50 2.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2CC)[nH]1 CHEMBL5220254 IC50 2.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cccnc3nc2OC)o1 CHEMBL5220715 IC50 2.2 nM
COc1ccc(S(=O)(=O)n2ccc3cc(/C=C/C(=O)NO)ccc32)cc1OC CHEMBL2048750 IC50 2.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3ccccc3c2)[nH]1 CHEMBL4745088 IC50 2.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(CC)ccc3c2)[nH]1 CHEMBL5219006 IC50 2.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccncc3nc2OC)[nH]1 CHEMBL5219039 IC50 2.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccc(=O)n(C)c3cc2OC)o1 CHEMBL5220454 IC50 2.4 nM
CC(C)[C@H](N)C(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL5314582 IC50 2.4 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C(\F)CCS)OC1=O CHEMBL4441774 IC50 2.46 nM
O=C(/C=C/c1ccc2cccnc2c1)NCCCCCC(=O)NO CHEMBL484073 IC50 2.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3n(C)c2=O)[nH]1 CHEMBL5219590 IC50 2.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)cc2)[nH]1 CHEMBL5219739 IC50 2.5 nM
COc1ccc(-c2nc(C(=O)NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc1 CHEMBL5275259 IC50 2.6 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827894 IC50 2.62 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccncc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827517 IC50 2.8 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5271471 IC50 2.8 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827814 IC50 2.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cn(C)c3ccccc23)[nH]1 CHEMBL4742026 IC50 2.9 nM
O=C(/C=C/c1ccc(Cl)cc1F)NCCCCCC(=O)NO CHEMBL484489 IC50 3.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 Ki 3.0 nM
COc1ncc(-c2cc(OCCCCCCC(=O)NO)c3ncnc(C)c3c2)cc1F CHEMBL4536105 IC50 3.0 nM
CC(/C=C/c1ccccc1)=C\C(=O)NCCCCCC(=O)NO CHEMBL490018 IC50 3.1 nM
CC(C)(C)OC(=O)NCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3317816 IC50 3.1 nM
COc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4237803 Ki 3.1 nM
O=C(COc1ccc(CNCCc2c[nH]c3ccccc23)c(F)c1)NO CHEMBL5185297 IC50 3.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3ncccc3c2)[nH]1 CHEMBL5218535 IC50 3.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3ccncc3)cc2)[nH]1 CHEMBL5218926 IC50 3.1 nM
Nc1nn(-c2ccccc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5415232 IC50 3.1 nM
COc1ccc(/C=N/NC(=O)CCCCCCCC(=O)NO)cc1 CHEMBL5269123 IC50 3.12 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3cccnc3cc2OC)o1 CHEMBL4862556 IC50 3.2 nM
Nc1nc2cc(-c3nn(CCCCCCC(=O)NO)c4ncnc(N)c34)ccc2o1 CHEMBL4846560 IC50 3.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccncc3nc2OC)o1 CHEMBL5219490 IC50 3.2 nM
COc1cc2ncnc(Nc3ccc(Br)cc3)c2cc1OCCCCCCC(=O)NO CHEMBL3759186 IC50 3.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nn(C)cc3c2)[nH]1 CHEMBL5219969 IC50 3.3 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)NC1=O CHEMBL3593407 IC50 3.38 nM
COc1ccc(-c2cc(OCCN(C)c3ncc(C(=O)NO)cn3)c3ncnc(C)c3c2)cn1 CHEMBL4462577 IC50 3.4 nM
CNC(=O)CCCCCCCn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21 CHEMBL4870348 IC50 3.4 nM
O=C(CCCC(=O)NCCc1ccccc1)NO CHEMBL3086768 IC50 3.5 nM
COc1ccc(F)c(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4799886 IC50 3.5 nM
Cc1ccc(CN2CCC(c3noc(CN(C)c4ncc(C(=O)NO)cn4)n3)CC2)cc1 CHEMBL4517151 IC50 3.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638330 IC50 3.6 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCC2(CC1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637745 IC50 3.6 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccc(Cl)cc3)ccc12)NO CHEMBL4786350 IC50 3.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(c2)C2CCC3C2)[nH]1 CHEMBL4859950 IC50 3.7 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)Nc1nc(-c2ccccc2)cs1)OCc1ccccc1 CHEMBL2022825 IC50 3.9 nM
COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cc1 CHEMBL3828518 IC50 3.9 nM
C/C=C1\NC(=O)[C@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL4061025 IC50 3.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1cccnc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4639206 IC50 3.9 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4790137 IC50 3.9 nM
COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(=O)NO)C(=O)NCCc3c(-c4ccccc4)[nH]c4ccccc34)c2c1 CHEMBL216641 IC50 4.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc3cc(F)ccc3n2)nc1 CHEMBL1801250 IC50 4.0 nM
O=C(/C=C/c1ccc2c(ccn2S(=O)(=O)c2ccccc2)c1)NO CHEMBL2048746 IC50 4.0 nM
Nc1ccc(-c2nc(N3CCOCC3)c3ncn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4785064 IC50 4.0 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3cccc(Cl)c3)ccc12)NO CHEMBL4792980 IC50 4.0 nM
Nc1ncc(-c2nc(N3CCOCC3)c3ccn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4744689 IC50 4.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cnccn3)cc2)[nH]1 CHEMBL5219422 IC50 4.1 nM
CCOc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4776328 IC50 4.2 nM
COc1ccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)cc1 CHEMBL4788954 IC50 4.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(-n4cccn4)ccc3c2)[nH]1 CHEMBL5220720 IC50 4.2 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2cccc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593409 IC50 4.39 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccccc3F)ccc12)NO CHEMBL4786031 IC50 4.4 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2ccnc(c2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593411 IC50 4.42 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4648704 IC50 4.5 nM
COc1ccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)cc1OC CHEMBL4793650 IC50 4.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4646915 IC50 4.7 nM
COc1ccc(-c2cc(C(=O)NCc3ccc(C(=O)NO)cc3)ccn2)cc1 CHEMBL5435925 IC50 4.71 nM
COc1cc(OC)cc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4788942 IC50 4.8 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2C)c1 CHEMBL3356924 IC50 5.0 nM
COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 CHEMBL3759059 IC50 5.0 nM
CC(C)C[C@H]1CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCCC(=O)NO)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1 CHEMBL585939 IC50 5.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4785376 IC50 5.0 nM
C=CC(=O)Nc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OCc1cn(CCCC(=O)NO)nn1 CHEMBL4794998 IC50 5.0 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3cccc(C(F)(F)F)c3)ccc12)NO CHEMBL4782066 IC50 5.0 nM
CCCC[C@H](NC(=O)[C@H](CN)c1c(C)[nH]c2ccc(O)cc12)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4867665 IC50 5.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2c(c1)CC(=O)N2CCN1CCOCC1 CHEMBL4848938 IC50 5.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2c(c1)CC(=O)N2CCCN1CCOCC1 CHEMBL4856764 IC50 5.0 nM
CN(C)CCNc1ccc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)ncc2c1 CHEMBL4856052 IC50 5.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(-c3ccccc3)[nH]c2=O)[nH]1 CHEMBL5219338 IC50 5.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ccc(C(=O)NO)cc4)cc3n2)cn1 CHEMBL5278968 IC50 5.0 nM
CN1c2ccc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cc2C(=O)N2CCc3c([nH]c4ccc(O)cc34)C21 CHEMBL5435505 IC50 5.0 nM
CCC(=O)CCCCC[C@H](NC(=O)CC1CC2(C1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638976 IC50 5.1 nM
Cn1cc(CN2CC3(CCN(c4ncc(C(=O)NO)cn4)C3)C2)c2ccc(C#N)cc21 CHEMBL5093798 IC50 5.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2F)o1 CHEMBL5220408 IC50 5.1 nM
Cc1[nH]c2ccccc2c1CCNS(=O)(=O)c1ccc(/C=C/C(=O)NO)cc1 CHEMBL3329991 IC50 5.13 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCC1c2ccccc2-c2ccccc21)OCc1ccccc1 CHEMBL2022829 IC50 5.2 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=S)Nc3ccccc3)CC2)nc1 CHEMBL3952742 IC50 5.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1C[C@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644118 IC50 5.2 nM
CCC(=O)CCCCC[C@H](NC(=O)C1=NOC2(CCN(C)CC2)C1)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4633758 IC50 5.2 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccccc3Cl)ccc12)NO CHEMBL4792567 IC50 5.2 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3n2)c1 CHEMBL4777182 IC50 5.3 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSC(=O)CCCCCCC)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622730 IC50 5.3 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CC2(C1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4641343 IC50 5.4 nM
COc1ccccc1-c1ccc2c(NC(=O)CCCCCCC(=O)NO)n[nH]c2c1 CHEMBL4786063 IC50 5.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(ccc(=O)n3C)c2)[nH]1 CHEMBL5218980 IC50 5.4 nM
O=C(CCCCCCn1cc(-c2ncnc3[nH]ccc23)cn1)NO CHEMBL4060201 IC50 5.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C4CC4)nc3cc2F)o1 CHEMBL5219978 IC50 5.9 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL235674 IC50 6.0 nM
O=C(NO)c1cnc(NC2(c3c(F)cccc3F)CC2)nc1 CHEMBL3655993 IC50 6.0 nM
O=C(CCCCCCn1cnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21)NO CHEMBL4749655 IC50 6.0 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3c2)c1F CHEMBL4776974 IC50 6.0 nM
CCNNC(=O)c1ccc(CNC(=O)Nc2cccc3cccnc23)cc1 CHEMBL5189990 IC50 6.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(-c2cn(CS(=O)(=O)c3ccccc3)nn2)cc1 CHEMBL5393987 Ki 6.2 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCCN)NC2=O CHEMBL3317815 IC50 6.3 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cccs2)cc1)NO CHEMBL3758735 IC50 6.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4748244 IC50 6.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1C[C@@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4634829 IC50 6.5 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCCCNC(=O)O[C@@H]1CC/C=C/CCC1)NC2=O CHEMBL4291290 IC50 6.6 nM
COc1cc2ncnc(Nc3ccc(Cl)cc3Cl)c2cc1OCCCCCC(=O)NO CHEMBL3633769 IC50 6.8 nM
CC(C)CCN(CCCCCCC(=O)NO)c1ncc(C(=O)NCCCn2ccnc2)s1 CHEMBL4170617 IC50 6.8 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccccn2)cc1)NO CHEMBL3758870 IC50 6.9 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL2448576 IC50 7.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4636652 IC50 7.1 nM
CN1CC(C(=O)N[C@@H](CCCCCC(=O)c2ncco2)c2ncc(-c3ccc(F)cc3)[nH]2)C1 CHEMBL4632775 IC50 7.1 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C(F)=C/CCS)NC1=O CHEMBL4446027 IC50 7.42 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCCCCCCC)OC(=O)[C@H](CCCCN)NC1=O CHEMBL5086750 IC50 7.5 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL3098602 IC50 8.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc4ccccc4c3)CCOCC2)cc1 CHEMBL4642874 IC50 8.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1ccccc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644387 IC50 8.1 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@H](/C=C/C(=O)NO)CC3)cc21 CHEMBL3309297 IC50 8.2 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1ncc(-c2ccccc2F)[nH]1 CHEMBL4644307 IC50 8.5 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCOCCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4869000 IC50 8.5 nM
CC/C=C\CCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830536 Ki 8.6 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 9.0 nM
O=C(NO)c1cnc(NCc2ccc(-c3ccccc3)cc2)nc1 CHEMBL3655984 IC50 9.0 nM
Cn1c(CCCC(=O)O)nc2cc(N(CCCl)CCCl)ccc21 CHEMBL487253 IC50 9.0 nM
O=C(NO)c1cnc(NC2(c3cc(C(F)(F)F)ccc3F)CC2)nc1 CHEMBL3655995 IC50 9.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Cc3cc4ccccc4[nH]3)CC2)nc1 CHEMBL3935353 IC50 9.0 nM
COc1ccc(-c2ccc3c(NC(=O)CCCCCCC(=O)NO)n[nH]c3n2)cc1 CHEMBL4776599 IC50 9.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL443392 IC50 9.0 nM
CCC(=O)CCCCC[C@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL4873847 IC50 9.0 nM
CCOC(=O)c1cc2cc(OC)c(-c3cnc([C@H](CCCCCC(=O)CC)NC(=O)[C@H]4CC45CCN(CC)CC5)[nH]3)cc2o1 CHEMBL4758559 IC50 9.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4646582 IC50 9.2 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C(F)(F)[C@@H](/C=C/CCS)NC1=O CHEMBL4516759 IC50 9.25 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)ncc1Cl CHEMBL4855319 IC50 9.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)ccc2OC)[nH]1 CHEMBL4759606 IC50 9.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC(F)(F)F)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4632432 IC50 9.8 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(-c2cn(CCc3ccccn3)nn2)cc1 CHEMBL5411914 Ki 9.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3ncccc3c2)[nH]1 CHEMBL5219241 IC50 9.9 nM
CC1(C)CC(=O)Nc2ccc(NC(=O)CCCCCCC(=O)NO)cc21 CHEMBL3311466 IC50 10.0 nM
CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](C)NC1=O CHEMBL257972 Ki 10.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cn[nH]c4)cc3)CCCCC2)cc1 CHEMBL4639966 IC50 10.0 nM
CN1C(=O)Cc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)ccc21 CHEMBL4848779 IC50 10.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc2c(c1)ncn2CCN1CCOCC1 CHEMBL4853232 IC50 10.0 nM
COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCOc5ccc(C(=O)NO)cc5)c4)nc3c2)c1 CHEMBL5181688 IC50 10.0 nM
COc1ccc(-c2cc(-c3ccn(Cc4ccc(C(=O)NO)cc4)n3)ccn2)cc1 CHEMBL5434546 IC50 10.28 nM
CCCN1CCC2(CC1)C[C@@H]2C(=O)N[C@@H](CCCCCC(=O)CC)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4640939 IC50 10.3 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cccnc2)cc1)NO CHEMBL3759794 IC50 10.8 nM
CN1CCN(CCn2ncc3cc(C(=O)Nc4cc(-c5ccccc5)ccc4N)ccc32)CC1 CHEMBL3983272 IC50 11.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(C2=CC3SC=NC3C=C2)[nH]1 CHEMBL5220815 IC50 11.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C)c3n2)cn1 CHEMBL3827281 IC50 11.46 nM
O=C(/C=C/c1cccc(S(=O)(=O)c2ccc3ccccc3n2)c1)NO CHEMBL3973951 IC50 11.48 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4759472 IC50 11.7 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 12.0 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2cccc(C(F)(F)F)c2)N1 CHEMBL3353927 IC50 12.0 nM
O=C(NO)c1cnc(NC2(c3ccc(F)cc3F)CC2)nc1 CHEMBL3655992 IC50 12.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)cnc2c1 CHEMBL3899844 IC50 12.0 nM
C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCc1cn(CCCC(=O)NO)nn1 CHEMBL4759072 IC50 12.0 nM
C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL598797 IC50 12.6 nM
O=C(CCCCCCC(=O)Nc1ccc([19F])cc1)NO CHEMBL1923808 IC50 12.7 nM
COC(=O)NCc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 CHEMBL398420 IC50 13.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCC(=O)N2)c1 CHEMBL3356922 IC50 13.0 nM
O=C(O)c1cccc(-c2ccc(C3(C(=O)Nc4ccc(C(=O)NO)cc4)CCCC3)cc2)c1 CHEMBL4640415 IC50 13.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)cc2)o1 CHEMBL5219118 IC50 13.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CCC(F)(F)F)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4643947 IC50 13.1 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccccc3)ccc12)NO CHEMBL4782327 IC50 13.1 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccccc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4460552 IC50 13.26 nM
CCOP(=O)(CNCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)OCC CHEMBL470225 IC50 14.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc(Cl)cc2)nc1 CHEMBL1801238 IC50 14.0 nM
CCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830537 Ki 14.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3356923 IC50 14.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc2c(C3CC3)c(N3CCNCC3)ccc2c1 CHEMBL3971229 IC50 14.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)nc2)[nH]1 CHEMBL4754237 IC50 14.0 nM
CN(C)c1ccc(C(=O)N(CC(=O)NCc2ccccc2)Cc2ccc(C(=O)NO)cc2F)cc1 CHEMBL5187433 IC50 14.0 nM
CCCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4526892 IC50 14.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2Cl)[nH]1 CHEMBL5218651 IC50 14.0 nM
CC(=O)Nc1ccc(C(=O)Nc2cc(-c3ccncc3)ccc2N)cc1 CHEMBL5440469 Ki 14.0 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccncc2)cc1)NO CHEMBL3758281 IC50 14.2 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356916 IC50 15.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)c2ccc3cccc(F)c3n2)c1)NO CHEMBL3925939 IC50 15.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1cnc2c(C3CC3)c(N3CCNCC3)ccc2c1 CHEMBL3951875 IC50 15.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)ccc2c1 CHEMBL3927842 IC50 15.0 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(C(=O)NCCCCCCC(=O)NO)cc2)ncc1Cl CHEMBL4849606 IC50 15.0 nM
CN(C)CCN(C)c1ccc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)cnc2c1 CHEMBL4860757 IC50 15.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3o2)cc1 CHEMBL5078985 IC50 15.14 nM
O=C(CCCCCCC(=O)N/N=C/c1cnc(N(c2ccccc2)c2ccccc2)nc1)NO CHEMBL5188297 IC50 15.4 nM
O=C(CCCCCCC(=O)N/N=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1)NO CHEMBL5075729 IC50 15.4 nM
CC(C)c1cccc(=O)c(O)c1 CHEMBL48310 Ki 15.44 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(C(F)(F)F)cc2)nc1C#N CHEMBL4797893 IC50 15.6 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL1851943 Ki 16.0 nM
CC(/C=C/C(=O)NO)=C\[C@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL164868 IC50 16.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C(F)(F)F)ccc2OC)[nH]1 CHEMBL4747553 IC50 16.0 nM
Nc1nc(-c2ccco2)c2cnn(Cc3cccc(OCCCCCCC(=O)NO)c3)c2n1 CHEMBL5201523 IC50 16.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3nccnc3cc2OC)[nH]1 CHEMBL5220576 IC50 16.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(O)ccc3o2)cc1 CHEMBL5086141 IC50 16.06 nM
Cc1ccc2nc3c4ccccc4c(NCCCCCCC(=O)NO)nn3c(=O)c2c1 CHEMBL5091856 IC50 16.3 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(OC)ccc3[nH]2)cc1 CHEMBL5080511 IC50 16.35 nM
COc1cc2ccn(CCOc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)c2cc1OC CHEMBL4176214 IC50 16.6 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3s2)cc1 CHEMBL5087431 IC50 16.92 nM
O=C(NO)c1cnc(NC2(c3cccc(F)c3F)CC2)nc1 CHEMBL3656012 IC50 17.0 nM
O=C(NO)c1cnc(NC2(c3ccc(Cl)c(Cl)c3)CC2)nc1 CHEMBL3656010 IC50 17.0 nM
O=C(NO)c1cnc(NC2(c3ccc4c(c3)OCO4)CC2)nc1 CHEMBL3655997 IC50 17.0 nM
O=C(NO)c1ccc(CNC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)cc1 CHEMBL4225914 IC50 17.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(Br)cc3)CCOCC2)cc1 CHEMBL4634521 IC50 17.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1ccc(OC)cc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4647014 IC50 17.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4649628 IC50 17.7 nM
Cc1ccc2nc3c4ccccc4c(NCCCCCCCC(=O)NO)nn3c(=O)c2c1 CHEMBL5092046 IC50 17.7 nM
O=C(NO)c1cnc(N2CCN(C(/C=C/c3ccc(F)cc3)CO)CC2)nc1 CHEMBL594544 IC50 17.9 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830420 Ki 18.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830422 Ki 18.0 nM
O=C(CCCCCCC(=O)Nc1ccc2c(c1)CCC(=O)N2)NO CHEMBL3311465 IC50 18.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3F)CC2)nc1 CHEMBL3655959 IC50 18.0 nM
CC(C)[C@@H](C(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1)c1ccccc1 CHEMBL4106624 IC50 18.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(C)nc2OC)[nH]1 CHEMBL4748516 IC50 18.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(OC)nc2OC)[nH]1 CHEMBL4754365 IC50 18.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1[nH]c(-c2ccccc2)nc1C(N)=O CHEMBL4776685 IC50 18.0 nM
O=C(NO)c1ccc(CNC(=O)c2ccc3cccc(OCc4ccc(F)cc4)c3n2)cc1 CHEMBL5280863 IC50 18.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/C(F)(F)CS)OC1=O CHEMBL4467713 IC50 18.49 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4632614 IC50 18.5 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3[nH]2)cc1 CHEMBL5083249 IC50 18.54 nM
CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)C2=N[C@@](C)(CS2)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL1173445 IC50 18.65 nM
COc1cc(Oc2ccc3nc(/C=C/C(=O)NO)ccc3c2)cc(OC)c1OC CHEMBL4644775 IC50 18.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1C[C@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645468 IC50 18.7 nM
Cc1ccccc1-c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 CHEMBL3758191 IC50 18.8 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 Ki 19.0 nM
O=C(NO)c1cnc(NC2(c3cccc(OC(F)(F)F)c3)CC2)nc1 CHEMBL3655994 IC50 19.0 nM
O=C(NO)c1cnc(NC2(c3ccc(F)c(Cl)c3)CC2)nc1 CHEMBL3656000 IC50 19.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc2c(cnn2CCN2CCOCC2)c1 CHEMBL3922439 IC50 19.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(C2=CC3OC=NC3C=C2)[nH]1 CHEMBL5221068 IC50 19.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(-c2cn(C[S+]([O-])c3ccccc3)nn2)cc1 CHEMBL5400421 IC50 19.0 nM
COc1ccccc1NC(=O)N[C@H](C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 CHEMBL5284956 IC50 19.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4788911 IC50 19.7 nM
N=C/C=N/c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL1164671 IC50 20.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2coc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL2436595 IC50 20.0 nM
O=C(CCCCCCNC(=O)c1ccc2c(c1)CCC(=O)N2)NO CHEMBL3311472 IC50 20.0 nM
CCS/C(Nc1ccccc1)=C(\C#N)C(=O)N/N=C\c1ccc(Cl)cc1Cl CHEMBL4171675 IC50 20.0 nM
CN(C)Cc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 CHEMBL5283887 IC50 20.0 nM
O=C(CCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621296 IC50 20.4 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2ccnc(c2)CNC(=O)C[C@@H](/C=C/CCS)NC1=O CHEMBL3593415 IC50 20.77 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(C)C CHEMBL1830424 Ki 21.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 CHEMBL2417782 IC50 21.0 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCN)NC2=O CHEMBL3317814 IC50 21.0 nM
O=C(NO)c1cnc(NC2(c3cc4ccccc4s3)CC2)nc1 CHEMBL3655979 IC50 21.0 nM
O=C(NO)c1cnc(NC2(c3ccc(C(F)(F)F)c(F)c3)CC2)nc1 CHEMBL3656006 IC50 21.0 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cncnc2)cc1)NO CHEMBL3758492 IC50 21.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C(F)=C/CCS)OC1=O CHEMBL4529140 IC50 21.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4550526 IC50 21.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3c[nH]c(-c4ccccc4)n3)CCCC2)cc1 CHEMBL4640356 IC50 21.0 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1cc(-c2ccccc2F)on1 CHEMBL4637836 IC50 21.0 nM
Cc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2Cc1ccc(C(=O)NO)cc1 CHEMBL4781628 IC50 21.0 nM
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)Nc1ccc(C(=O)NO)cc1)c1nnc(C)n1-2 CHEMBL4850926 IC50 21.0 nM
COc1ccc(C(=O)N[C@H](CNCc2ccc(C(=O)Nc3ccccc3N)cc2)Cc2c[nH]c3ccccc23)cc1 CHEMBL4062598 IC50 21.2 nM
COc1ccccc1-c1cnc(C(=O)NCCCCCCC(=O)NO)s1 CHEMBL5413000 IC50 21.29 nM
Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1 CHEMBL272980 IC50 22.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NCc3ccc(/C=C/C(=O)NO)cc3)cc21 CHEMBL3309291 IC50 22.0 nM
O=C(NO)c1cnc(NC2(c3cc(Cl)cc(Cl)c3)CC2)nc1 CHEMBL3656015 IC50 22.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3c(F)cccc3F)CC2)nc1 CHEMBL3916028 IC50 22.0 nM
CC(C)C[C@@H](C(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1)c1ccccc1 CHEMBL4113844 IC50 22.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCOCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4876610 IC50 22.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCC(N(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645863 IC50 22.6 nM
Cc1cc(C2(Nc3ncc(C(=O)NO)cn3)CC2)ccc1F CHEMBL3656011 IC50 23.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc2nn(CCN3CCOCC3)cc2c1 CHEMBL3912393 IC50 23.0 nM
O=C(CCCCCCNC(=O)c1ccc(CNC2(c3ccccc3)CC2)cc1)NO CHEMBL4173338 IC50 23.0 nM
CC(C)(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4241370 Ki 23.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc3ccncc3c2)[nH]1 CHEMBL5220120 IC50 23.0 nM
Cc1ccc(Nc2nc(Cl)nc3c2ncn3Cc2ccc(C(=O)Nc3ccccc3N)cc2)cc1 CHEMBL4795802 IC50 23.1 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Br)ccc3o2)cc1 CHEMBL5083475 IC50 23.75 nM
Nc1ccc(-c2ccncc2)cc1NC(=O)c1cnc2c(c1)cc(C1CC1)n2CCN1CCOCC1 CHEMBL3914604 IC50 24.0 nM
COc1ccc(NC(=O)N2CCC(Nc3ncc(C(=O)NO)cn3)(c3ccccc3)CC2)cc1 CHEMBL3916257 IC50 24.0 nM
CN1CCC(C(=O)N[C@@H](CCCCCC(=O)c2nccs2)c2ncc(-c3ccc(F)cc3)[nH]2)CC1 CHEMBL4647458 IC50 24.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCN2C4CCC2c2c(cccc24)-c2cnc1[nH]2)CC3 CHEMBL4862470 IC50 24.0 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2CCCCCCCCC(=O)NO CHEMBL4846776 IC50 24.0 nM
CCOC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4464421 IC50 24.5 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(I)cc3)nn2)c1)NO CHEMBL1091475 IC50 24.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637397 IC50 24.6 nM
O=C(CCCCCCNC(=O)c1ccc2[nH]c(=O)ccc2c1)NO CHEMBL3311471 IC50 25.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@@H](CCC(=O)NO)CC3)cc21 CHEMBL3309300 IC50 25.0 nM
O=C(/C=C/c1ccc(CNC2CC2c2ccccc2)cc1)NO CHEMBL4166084 IC50 25.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(F)c2OC)[nH]1 CHEMBL4751762 IC50 25.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)CNC3=O)nc1 CHEMBL470791 Kd 25.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(-c3ccccc3)nn2)c1)NO CHEMBL1094709 IC50 25.1 nM
O=C(CCCCCN1C(=O)c2cccc3c(N4CCOCC4)ccc(c23)C1=O)NO CHEMBL4160632 IC50 25.6 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccncc3)ccc12)NO CHEMBL4792025 IC50 25.9 nM
CN(C)CC(C)(C)Cn1c(CC(C)(C)C)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL1830397 Ki 26.0 nM
Nc1ccccc1NC(=O)c1ccc(NC(=O)CCN2C(=O)C3(OCCCO3)c3cc(Br)ccc32)cc1 CHEMBL4092753 IC50 26.0 nM
C=CC(=O)Nc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OCc1cn(CCC(=O)NO)nn1 CHEMBL4759697 IC50 26.0 nM
COc1cccc2ccc(C(=O)NCc3ccc(C(=O)NO)cc3)nc12 CHEMBL5270568 IC50 26.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(OC)ccc3o2)cc1 CHEMBL5093099 IC50 26.13 nM
Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL1630208 IC50 26.5 nM
O=C(NO)c1cnc(N2CCC(NC(=O)c3cnc(-n4cccn4)nc3O)CC2)nc1 CHEMBL5172182 IC50 26.6 nM
CCC(=O)CCCCCC(NC(=O)c1cncs1)c1[nH]c(-c2ccccc2)nc1C(N)=O CHEMBL4742036 IC50 26.7 nM
CCC(=O)CCCCC[C@H](NC(=O)C12CCN(CC1)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4741084 IC50 26.9 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccccc1 CHEMBL271741 IC50 27.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL3215861 Ki 27.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3098604 IC50 27.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccccc3F)CC2)nc1 CHEMBL3977741 IC50 27.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)c(F)cc2OC)[nH]1 CHEMBL4793832 IC50 27.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)cc(F)c2OC)[nH]1 CHEMBL4794196 IC50 27.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(C3CCCCC3)nn2)c1)NO CHEMBL1094707 IC50 27.5 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3cc(CO)cc(CO)c3)nn2)c1)NO CHEMBL1088736 IC50 27.8 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(F)ccc3o2)cc1 CHEMBL5093836 IC50 27.89 nM
O=C1NCCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356527 IC50 28.0 nM
O=C(NO)c1cnc(NCc2cccc(Cl)c2)nc1 CHEMBL3655917 IC50 28.0 nM
O=C(NO)c1cnc(NC2(c3ccc(CO)cc3)CC2)nc1 CHEMBL3655974 IC50 28.0 nM
CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCc2cccc(n2)-c2cccc(n2)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL4798363 IC50 28.0 nM
O=C(CCCCCCNc1nn2c(=O)c3ccccc3nc2c2ccccc12)NO CHEMBL5087773 IC50 28.0 nM
CCCNNC(=O)c1ccc(NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(OC)cc2)cc1 CHEMBL4063938 IC50 28.04 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Cl)ccc3o2)cc1 CHEMBL5089712 IC50 28.08 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(C(F)(F)F)cc3)nn2)c1)NO CHEMBL1088734 IC50 28.5 nM
CC(=O)CCCCC[C@H](NC(=O)C1CCN(C)CC1)c1ncc(-c2ccc3ccccc3c2)[nH]1 CHEMBL468513 IC50 29.0 nM
O=C(CCCCCCC(=O)NO)NO CHEMBL320497 Ki 29.0 nM
O=C(NO)c1ccc(Cn2cc(-c3ccc(CN4CCCC4)cc3)nn2)cc1 CHEMBL4090165 IC50 29.0 nM
O=C(N[C@@H](CCCCNC(=O)c1ccccc1O)c1ncc(-c2ccc3ccccc3c2)[nH]1)c1cncs1 CHEMBL4753019 IC50 29.0 nM
O=C(N[C@@H](CCCCNC(=O)c1c(O)cccc1F)c1ncc(-c2ccc3ccccc3c2)[nH]1)c1cncs1 CHEMBL4753111 IC50 29.0 nM
O=C(CCCCCCCNc1nn2c(=O)c3ccccc3nc2c2ccccc12)NO CHEMBL5084865 IC50 29.4 nM
O=C(NO)c1cnc(NCc2ccc(F)c(Cl)c2)nc1 CHEMBL3655936 IC50 30.0 nM
C=C1CN(Cc2ccc(C(=O)Nc3ccccc3N)cc2)C(=O)c2ccccc21 CHEMBL4294949 IC50 30.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cn(C)nc3cc2OC)o1 CHEMBL5218487 IC50 30.0 nM
COc1ccc2c(c1)C1(OCCO1)C(=O)N2CCCCCCC(=O)NO CHEMBL5266413 IC50 30.0 nM
O=C(CCCCCCN1C(=O)C2(OCCO2)c2cccc(Cl)c21)NO CHEMBL5283721 IC50 30.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccncc3c2)cc1 CHEMBL5075425 IC50 30.14 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccccc3c2)cc1 CHEMBL5084347 IC50 30.51 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3cn2)cc1 CHEMBL5086924 IC50 30.94 nM
CC(C)(C)c1[nH]c2ccccc2c1[C@H]1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2F)C1 CHEMBL1093033 IC50 31.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1cnc2c(ccn2CCN2CCOCC2)c1 CHEMBL3913445 IC50 31.0 nM
COc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2Cc1ccc(C(=O)NO)cc1 CHEMBL4751879 IC50 31.0 nM
Nc1cc(F)ccc1NC(=O)C=Cc1cnn(CC=Cc2ccccc2)c1 CHEMBL5195471 Ki 31.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1C[C@@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4641048 IC50 31.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4640923 IC50 31.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCOCC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4649561 IC50 31.3 nM
O=C(CCCCCCC(=O)Nc1n[nH]c2cc(-c3ccsc3)ccc12)NO CHEMBL4792705 IC50 31.6 nM
Nc1ccc(-c2ccc(F)cc2)cc1NC(=O)c1ccccc1 CHEMBL1098337 IC50 32.0 nM
O=C(NO)c1cnc(NC2(c3cccc(C(F)(F)F)c3)CC2)nc1 CHEMBL3655990 IC50 32.0 nM
O=C(NO)c1cnc(NC2(c3cccc(Cl)c3)CC2)nc1 CHEMBL3655971 IC50 32.0 nM
Cc1ccc(-c2cc(C(=O)NCCCCCCCC(=O)NO)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL3883560 IC50 32.0 nM
CC(C)C[C@H]1CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCCC(=O)C(F)(F)F)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1 CHEMBL2012811 IC50 32.0 nM
CCS/C(Nc1ccccc1)=C(\C#N)C(=O)Nc1ccc(OC)cc1 CHEMBL4163794 IC50 32.0 nM
O=C(CCCCCCOc1ccc(-c2nc3ccc(-c4nc5ccccc5[nH]4)cc3[nH]2)cc1)NO CHEMBL5087772 IC50 32.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830396 Ki 33.0 nM
CCC[C@@H]1NC(=O)[C@H](C)NC(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2cn(CN(C)C)c3ccccc23)NC1=O CHEMBL2063396 Ki 33.0 nM
O=C1CC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356918 IC50 33.0 nM
O=C(CCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3758251 IC50 33.0 nM
O=C(CCCCCCN(Cc1ccc(F)cc1)c1ncc(C(=O)NCCCn2ccnc2)s1)NO CHEMBL4163681 IC50 33.0 nM
O=C(CCNC(=O)/C(Cc1ccc(O)c(Br)c1)=N/O)NO CHEMBL2047684 IC50 33.0 nM
O=C(NCCSSCCNC(=O)/C(Cc1ccc(O)c(Br)c1)=N/O)/C(Cc1ccc(O)c(Br)c1)=N/O CHEMBL83747 IC50 33.0 nM
O=C(CCCCCCNc1nn2c(=O)c3cc(Br)ccc3nc2c2ccccc12)NO CHEMBL5090447 IC50 33.0 nM
COc1ccc2c(ccn2CCOc2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c1 CHEMBL4159460 IC50 33.1 nM
CCCNNC(=O)c1ccc(CNC(=O)c2nc3ccccc3[nH]2)cc1 CHEMBL5081353 IC50 33.39 nM
O=C1CCC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356524 IC50 34.0 nM
O=C(NO)c1cnc(NC2(c3ccc(F)cc3Cl)CC2)nc1 CHEMBL3656013 IC50 34.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccccc3)CC2)nc1 CHEMBL3963102 IC50 34.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(Cl)c2OC)[nH]1 CHEMBL4753648 IC50 34.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nnccc3c2)[nH]1 CHEMBL5219074 IC50 34.0 nM
O=C(CCCCCCc1nc2ccc(Br)cc2[nH]1)NO CHEMBL2414098 IC50 34.1 nM
COc1ccc2c3c(oc2c1)CN([C@@H](Cc1ccccc1)C(=O)Nc1ccc(C(=O)NO)cc1)CC3 CHEMBL5419989 IC50 34.3 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4781191 IC50 34.4 nM
O=C(CCCCCCNc1nc2ccccc2nc1-c1nc2ccccc2o1)NO CHEMBL5269112 IC50 34.44 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@H](CCC(=O)NO)CC3)cc21 CHEMBL3309298 IC50 35.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCOCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4853593 IC50 35.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nccnc3c2)[nH]1 CHEMBL5219811 IC50 35.0 nM
C=CCOc1ccc2oc(C(=O)NCc3ccc(C(=O)NNCCC)cc3)cc2c1 CHEMBL5089744 IC50 35.77 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCC1)NO CHEMBL491316 Ki 36.0 nM
COc1ccc(N2CCN(S(=O)(=O)c3cccc(/C=C/C(=O)NO)c3)CC2)cc1 CHEMBL1958431 ED50 36.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3Cl)CC2)nc1 CHEMBL3655967 IC50 36.0 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc2c(c1)cc(C1CC1)n2CCN1CCOCC1 CHEMBL3952143 IC50 36.0 nM
C/C=C1\NC(=O)c2csc(n2)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622727 IC50 36.6 nM
O=C1NC[C@@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356925 IC50 37.0 nM
COc1cc2nc(-c3ccc(C)o3)nc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4854765 IC50 38.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)Nc1cccc2ccccc12)OCc1ccccc1 CHEMBL2022823 IC50 38.2 nM
Nc1ccc(-c2ccoc2)cc1NC(=O)c1ccccc1 CHEMBL1095095 IC50 39.0 nM
CN(C)CC(C)(C)Cn1c(CCc2ccccc2)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL460963 Ki 39.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCCC1)NO CHEMBL489332 Ki 39.0 nM
C[C@@H](Nc1ncc(C(=O)NO)cn1)c1ccccc1 CHEMBL3655944 IC50 39.0 nM
CCOC(=O)C1CC1c1ccc(OC)c(-c2cnc([C@H](CCCCCC(=O)CC)NC(=O)[C@H]3CC34CCN(CC)CC4)[nH]2)c1 CHEMBL4788187 IC50 39.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCc1cccc2ccccc12)OCc1ccccc1 CHEMBL2022833 IC50 39.6 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3cnccc3c2)cc1 CHEMBL5075150 IC50 39.63 nM
O=C(NO)c1cnc(NC2(c3ccc(Cl)cc3)CC2)nc1 CHEMBL3656005 IC50 40.0 nM
Cc1cccc(C2(Nc3ncc(C(=O)NO)cn3)CC2)c1 CHEMBL3656003 IC50 40.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL2012814 IC50 40.0 nM
Cc1cc(-c2ccc3c(c2)OCO3)nn1Cc1ccc(C(=O)NO)cc1 CHEMBL4228987 IC50 40.0 nM
O=C(CCCCCCNC(=O)c1cc(-c2ccc(F)cc2)[nH]n1)NO CHEMBL4225451 IC50 40.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCc1ccc2ccccc2c1)OCc1ccccc1 CHEMBL2022832 IC50 40.3 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCc1ccc(-c2ccccc2)cc1)OCc1ccccc1 CHEMBL2021937 IC50 40.7 nM
Cc1ccc(-c2cc(C)n(Cc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL4229248 IC50 41.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)=O)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4636123 IC50 41.0 nM
CCCC[C@H](NC(=O)[C@H](CN)c1c(C)[nH]c2ccc(OC)cc12)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4879154 IC50 41.0 nM
O=C(CCCCCONC(=O)c1ccc2ccccc2c1)NO CHEMBL4876405 IC50 41.0 nM
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)NCC4CN(CC(=O)NO)N=N4)cn1c23 CHEMBL5199795 IC50 41.0 nM
CCNNC(=O)c1ccc(Cn2nnnc2-c2cccs2)cc1 CHEMBL5197503 IC50 41.0 nM
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)NCc4cn(CCCCCCC(=O)NO)nn4)cn1c23 CHEMBL4649154 IC50 41.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cn(C)c3ccccc3c2=O)[nH]1 CHEMBL5218749 IC50 41.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3cnccc3n2)cc1 CHEMBL5074837 IC50 41.42 nM
O=C(CCCCCCC(=O)Nc1ccc([C@H]2O[C@@H](CSc3nc(-c4ccccc4)c(-c4ccccc4)o3)C[C@@H](c3ccc(CO)cc3)O2)cc1)NO CHEMBL356769 Ki 42.0 nM
O=C(CCCCCNC(=O)c1cc(-c2ccc(F)cc2)[nH]n1)NO CHEMBL4226433 IC50 42.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2nc3ccccc3s2)cc1 CHEMBL5084847 IC50 42.03 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccccc3)nn2)c1)NO CHEMBL483693 IC50 43.0 nM
Nc1ccc(-c2ccco2)cc1NC(=O)c1ccccc1 CHEMBL1097651 IC50 43.0 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccc(F)cc3)CC2)nc1 CHEMBL3961733 IC50 43.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc([N+](=O)[O-])ccc2OC)[nH]1 CHEMBL4757813 IC50 43.0 nM
C=CC(=O)Nc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OCc1cn(CCCCC(=O)NO)nn1 CHEMBL4783641 IC50 43.0 nM
Cc1ccc(COc2cccc3ccc(C(=O)NCc4ccc(C(=O)NO)cc4)nc23)cc1 CHEMBL5274591 IC50 43.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCc1c2ccccc2cc2ccccc12)OCc1ccccc1 CHEMBL2022834 IC50 43.6 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CCNC3)CC2)nc1 CHEMBL513568 IC50 44.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccccc1)NO CHEMBL1083439 Ki 44.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=N[C@@H](c3ccc(O)cc3)CS2)cc1 CHEMBL2407719 IC50 44.0 nM
CC(C)C(C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 CHEMBL191091 IC50 44.0 nM
O=C(CCCCCONC(=O)c1cnc2ccccc2n1)NO CHEMBL4875953 IC50 44.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cn(C)nc3cc2OC)[nH]1 CHEMBL5221097 IC50 44.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)NC1CCCCC1)OCc1ccccc1 CHEMBL2022824 IC50 44.1 nM
Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)CNC(=O)O3)nc1 CHEMBL3286732 IC50 45.0 nM
O=C(CCCCCCC(=O)Nc1ccc2[nH]c(=O)ccc2c1)NO CHEMBL3311464 IC50 45.0 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622729 IC50 45.0 nM
O=C(CCCCCCNC(=O)c1cnc(N(c2ccccc2)c2ccccc2Cl)nc1)NO CHEMBL3693786 IC50 45.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)Nc1ccccc1-c1ccccc1)OCc1ccccc1 CHEMBL2022826 IC50 45.2 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCc1ccc([N+](=O)[O-])cc1)OCc1ccccc1 CHEMBL2022830 IC50 45.5 nM
Cc1ccc(NC(=O)N2CCC(Nc3ncc(C(=O)NO)cn3)(c3ccccc3)CC2)cc1 CHEMBL3923499 IC50 46.0 nM
O=C(CCCCCCOc1cccc(-c2nc3ccccc3[nH]2)c1)NO CHEMBL5086208 IC50 46.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 CHEMBL5087971 IC50 46.06 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)Nc1ccc(-c2ccccc2)cc1)OCc1ccccc1 CHEMBL2022827 IC50 46.6 nM
CC(CCCCCC(=O)NO)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL4095596 IC50 47.0 nM
Cc1ccc(-c2cc(C(F)(F)F)n(Cc3ccc(C(=O)NO)cc3)n2)cc1 CHEMBL4225331 IC50 47.0 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cn(-c3ccccc3)nn2)cc1)NO CHEMBL519491 IC50 47.5 nM
CC(C)(C)c1[nH]c2ccccc2c1[C@@H]1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2F)C1 CHEMBL1093335 IC50 48.0 nM
CC(C)(C)OC(=O)N1C(NCc2ccc(C(=O)Nc3ccccc3N)cc2)=NC(=O)C1Cc1c[nH]c2ccccc12 CHEMBL2407731 IC50 48.0 nM
O=C(CCCCCCNC(=O)c1cnc(N(c2ccccc2)c2ccccc2)nc1)NO CHEMBL2364628 IC50 48.0 nM
O=C1NCCC[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356915 IC50 48.0 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)NC1c2ccccc2-c2ccccc21)OCc1ccccc1 CHEMBL2022828 IC50 48.1 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(C3CCCCC3)nn2)c1)NO CHEMBL1094710 IC50 48.2 nM
O=C(N[C@@H](CCCCCCSSc1ccccn1)C(=O)OCc1cccc([N+](=O)[O-])c1)OCc1ccccc1 CHEMBL2022831 IC50 48.5 nM
COc1ccc(C2(Nc3ncc(C(=O)NO)cn3)CC2)cc1OC CHEMBL3656007 IC50 49.0 nM
O=C(CCCCCCOc1ccc2cc1COC/C=C/COCc1cccc(c1)-c1ccnc(n1)N2)NO CHEMBL3917405 IC50 49.0 nM
CN(C)c1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCC2)cc1 CHEMBL4636734 IC50 49.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCN2C4CCC2c2cc(ccc24)-c2cnc1[nH]2)CC3 CHEMBL4866612 IC50 49.0 nM
CC(=O)N1CCC(C(=O)Nc2cc(-c3cccs3)ccc2N)CC1 CHEMBL5176393 IC50 49.0 nM
CCCNNC(=O)/C=C/c1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL4444219 IC50 49.5 nM
CCCNNC(=O)/C=C/c1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL4597954 IC50 49.5 nM
CC(C)[C@H]1NC(=O)[C@@H](C)[C@@H](C/C=C\CCC(=O)O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC1=O CHEMBL402363 Ki 50.0 nM
Cc1coc(C(=O)CCCCC[C@H](NC(=O)C2CCN(C)CC2)c2ncc(-c3ccc(F)cc3)[nH]2)n1 CHEMBL4633968 IC50 50.0 nM
COc1cc2nc(-c3ccc(C)o3)cc(NCC3CCN(c4ncc(C(=O)NO)cn4)CC3)c2cc1OC CHEMBL4856110 IC50 51.0 nM
CCC(=O)CCCCC[C@H](NC(=O)c1cncs1)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4760209 IC50 51.3 nM
COc1cc(OC)cc(C2(Nc3ncc(C(=O)NO)cn3)CC2)c1 CHEMBL3655998 IC50 52.0 nM
O=C(CCCCCCNc1nn2c(=O)c3cc(Cl)ccc3nc2c2ccccc12)NO CHEMBL5076796 IC50 52.1 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(F)ccc3[nH]2)cc1 CHEMBL5089258 IC50 52.7 nM
O=C(NO)c1cnc(NCc2ccc3c(c2)OCO3)nc1 CHEMBL3655929 IC50 53.0 nM
COc1cccc(C2(Nc3ncc(C(=O)NO)cn3)CC2)c1 CHEMBL3655989 IC50 53.0 nM
CCC(=O)CCCCCC(NC(=O)c1cncs1)c1[nH]c(-c2ccccc2)nc1C(=O)NCCN(C)C CHEMBL4761318 IC50 53.1 nM
O=C(CCCCCCNC(=O)c1ncc(-c2ccccc2)o1)NO CHEMBL5416448 IC50 53.21 nM
O=C(/C=C/c1ccc(/C=C(/CNC2CC2)c2ccc(F)cc2)cc1)NO CHEMBL3758457 IC50 54.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(C(=O)NC3CCOC3)cc2)[nH]1 CHEMBL4761389 IC50 54.0 nM
O=C(CCCCCCNc1nn2c(=O)c3cc(F)ccc3nc2c2ccccc12)NO CHEMBL5093737 IC50 54.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)N2CCN(c3ccccn3)CC2)c1)NO CHEMBL1958424 ED50 55.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=N[C@H](c3ccccc3)CS2)cc1 CHEMBL2407718 IC50 56.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=NC(=O)C(c3ccccc3)N2)cc1 CHEMBL2407736 IC50 56.0 nM
O=C(NO)c1cnc(NCc2cccc(C(F)(F)F)c2)nc1 CHEMBL3655923 IC50 56.0 nM
O=C(CCCCCNc1nc(Cl)nc2c1ncn2Cc1ccccc1)NO CHEMBL3763444 IC50 56.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1cnc2c(N3CCNCC3)c(C3CC3)ccc2c1 CHEMBL3936840 IC50 56.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccnc2OC)[nH]1 CHEMBL4753639 IC50 56.0 nM
Nc1cccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)c1 CHEMBL468595 IC50 56.7 nM
Cc1ccccc1C1(Nc2ncc(C(=O)NO)cn2)CC1 CHEMBL3655996 IC50 57.0 nM
O=C(CCCCCONC(=O)c1cc2ccccc2[nH]1)NO CHEMBL4850081 IC50 57.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccccc3n2)cc1 CHEMBL5073909 IC50 57.31 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cnnn2Cc2ccc(F)cc2)cc1)NO CHEMBL487741 IC50 57.4 nM
O=C(CCCCCCNC(=O)c1ncc(-c2ccc(Br)cc2)o1)NO CHEMBL5399106 IC50 57.8 nM
Cc1cc(-c2nc3sc4c(c3c(=O)[nH]2)CCN(C)C4)cc(C)c1OCCCCCC(=O)NO CHEMBL4514808 IC50 58.0 nM
O=C(CCCCCCS)Nc1ccccc1 CHEMBL325676 IC50 58.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1nnc(-c2cc3ccccc3nc2OC)o1 CHEMBL4644657 IC50 58.2 nM
CN(C)CCOc1ccc(-c2cc(=O)c3c(O)cc(OCCCCCC(=O)NO)cc3o2)cc1 CHEMBL4798571 IC50 58.46 nM
CCC(=O)CCCCC[C@H](NC(=O)Cc1c(C)[nH]c2ccc(OC)cc12)c1ncc(-c2ccccc2)[nH]1 CHEMBL261735 IC50 59.0 nM
O=C(CCCCCCCNc1nn2c(=O)c3cc(Cl)ccc3nc2c2ccccc12)NO CHEMBL5093545 IC50 59.2 nM
COc1ccc(C(=O)N[C@H](COc2ccc(/C=C/C(=O)NO)cc2OC)Cc2c[nH]c3ccccc23)cc1 CHEMBL4070891 IC50 59.5 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cnc3ccccc3c2)cc1 CHEMBL5073024 IC50 59.64 nM
COc1ccc(NCc2ccc(C(=O)Nc3cc(-c4cccs4)ccc3O)cc2)cc1OC CHEMBL235413 IC50 60.0 nM
COc1ccc(NCc2ccc(C(=O)Nc3cc(-c4ccsc4)ccc3N)cc2)cc1OC CHEMBL399388 IC50 60.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(F)cc3)nn2)c1)NO CHEMBL1091474 IC50 60.0 nM
Cc1ccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)cc1 CHEMBL3356917 IC50 60.0 nM
COc1cc(OC)cc(C(=O)NOCCCCCC(=O)NO)c1 CHEMBL4645688 Ki 60.0 nM
COc1cc2c(NCc3ccc(C(=O)NO)cc3)cc(-c3ccc(C)o3)nc2cc1OCCCN1CCCC1 CHEMBL4872188 IC50 60.0 nM
Cc1cc(C)cc(C(=O)N(CCCCCC(=O)NO)CC(=O)NCc2ccccc2)c1 CHEMBL4090647 IC50 61.0 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1cnn(-c2ccc(F)cc2)c1 CHEMBL4632449 IC50 61.0 nM
Nc1cccc(F)c1C(=O)NCCCC[C@H](NC(=O)c1cncs1)c1ncc(-c2ccc3ccccc3c2)[nH]1 CHEMBL4749183 IC50 61.0 nM
C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCc1cn(CCC(=O)NO)nn1 CHEMBL4793338 IC50 61.0 nM
O=C(NO)c1cnc(NC2(c3ccc(F)c(F)c3)CC2)nc1 CHEMBL3656009 IC50 62.0 nM
Nc1ccc(-c2ccc(F)cc2)cc1NC(=O)C1CCOCC1 CHEMBL3828396 IC50 62.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C#N)ccc2OC)[nH]1 CHEMBL4797791 IC50 62.0 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4797623 IC50 62.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(C(F)(F)F)c2OC)[nH]1 CHEMBL4794888 IC50 63.0 nM
COc1cccc(-c2ccc3c(NC(=O)CCCCCC(=O)NO)n[nH]c3c2)c1 CHEMBL4782988 IC50 63.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccccc3)nn2)c1)NO CHEMBL519668 IC50 63.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-n3nc(C)cc3C)cc2)[nH]1 CHEMBL4756846 IC50 64.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(Cl)cc2OC)[nH]1 CHEMBL4781134 IC50 64.0 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(CC(O)c3cccc(Br)c3)nn2)c1)NO CHEMBL483893 IC50 64.4 nM
COc1ccccc1C(=O)N[C@H](COc1cccc(/C=C/C(=O)NO)c1)Cc1c[nH]c2ccccc12 CHEMBL3354920 IC50 64.8 nM
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)OCc4cn(CCCCCCCC(=O)NO)nn4)cn1c23 CHEMBL4638706 IC50 65.0 nM
O=C(CCCCCCCNc1nn2c(=O)c3cc(Br)ccc3nc2c2ccccc12)NO CHEMBL5078723 IC50 65.1 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=NC(=O)C(Cc3ccccc3)N2)cc1 CHEMBL2407735 IC50 66.0 nM
CN(C)c1ccc(C(=O)N(CCCCCC(=O)NO)CC(=O)NCc2ccccc2)cc1 CHEMBL4069631 IC50 66.0 nM
Nc1ccc(F)cc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1 CHEMBL4087968 IC50 66.5 nM
CN1C(=O)C2CN(Cc3c2c2ccccc2n3Cc2ccc(/C=C/C(=O)NO)cc2)C1=O CHEMBL4065219 Ki 66.51 nM
O=C1CCC[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356523 IC50 67.0 nM
CCCNNC(=O)c1ccc(NCc2ccccc2)cc1 CHEMBL4534191 IC50 67.48 nM
O=C1C[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356929 IC50 68.0 nM
O=C(NCCCCCCS)c1cc(-c2cnccn2)n[nH]1 CHEMBL3760013 IC50 68.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCC(=O)NO)OC1=O CHEMBL4099942 IC50 69.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2cccc(n2)CNC(=O)C[C@@H](/C=C/CCS)NC1=O CHEMBL3593413 IC50 69.8 nM
COc1ccc(NCc2ccc(C(=O)Nc3cc(-c4ccoc4)ccc3N)cc2)cc1OC CHEMBL235192 IC50 70.0 nM
O=C(/C=C/c1ccc(C(=O)N/N=C/c2ccc(O)c(O)c2O)cc1)NO CHEMBL1213457 Ki 70.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H](C)N(C)C(=O)C[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL2012813 IC50 70.0 nM
CN1C(=O)CCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356526 IC50 70.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc2c(c1)cc(C1CC1)n2CCN1CCOCC1 CHEMBL3981202 IC50 70.0 nM
O=C(/C=C/c1ccc(CONC(=O)c2ccc3ccccc3n2)cc1)NO CHEMBL4459795 Ki 70.0 nM
O=C(N[C@@H](CCCCNC(=O)c1ncccc1O)c1ncc(-c2ccc3ccccc3c2)[nH]1)c1cncs1 CHEMBL4782216 IC50 70.0 nM
CCCCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4757047 IC50 70.03 nM
COc1ccc2c3c(n(Cc4ccc(C(=O)NO)cc4)c2c1)CN1CC3C(=O)N(C)C1=O CHEMBL4062190 Ki 70.8 nM
CCOC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 CHEMBL399494 IC50 71.0 nM
Nc1ccc(-c2ccsc2)cc1NC(=O)c1ccc(N2CCC3(CCNC3)CC2)nc1 CHEMBL511797 IC50 71.0 nM
O=C(NO)c1cnc(NCc2ccc(Cl)cc2)nc1 CHEMBL3655919 IC50 71.0 nM
Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL253868 IC50 72.0 nM
O=C(NCCCCCCS)c1cc(-c2ccncc2)n[nH]1 CHEMBL3759562 IC50 72.0 nM
O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCCN(Cc3ccccc3)CC1)O2)NO CHEMBL3759808 IC50 72.0 nM
COc1ccc(COc2cccc3ccc(C(=O)NCc4ccc(C(=O)NO)cc4)nc23)cc1 CHEMBL5267546 IC50 72.0 nM
Nc1ccccc1NC(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCCN3)cc2)cc1 CHEMBL5407714 IC50 72.0 nM
Cc1cc(C(F)(F)F)cc(C2(Nc3ncc(C(=O)NO)cn3)CC2)c1 CHEMBL3656016 IC50 73.0 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCOCC1)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4796175 IC50 73.8 nM
O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3cccc(F)c3)CC2)nc1 CHEMBL3934237 IC50 74.0 nM
Nc1ccccc1NC(=O)c1ccc(Cn2cc(-c3ccc(C(=O)NCc4cccnc4)cc3)nn2)cc1 CHEMBL4065412 IC50 75.0 nM
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C2\NC(=O)c3ccccc32)cc1 CHEMBL4561073 IC50 75.0 nM
O=C(NO)c1ccc(CN2C(=O)/C(=C3\Nc4ccccc4\C3=N/O)c3cc(Br)ccc32)cc1 CHEMBL4764495 IC50 75.0 nM
Cc1ccc(-c2cc(C)nn2Cc2ccc(C(=O)NO)cc2)cc1 CHEMBL4228291 IC50 76.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C(C)C)ccc2OC)[nH]1 CHEMBL4753460 IC50 76.0 nM
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)NCc4cn(CCCCCCCC(=O)NO)nn4)cn1c23 CHEMBL4644409 IC50 76.0 nM
CCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4786837 IC50 76.57 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccc(F)cc3)nn2)c1)NO CHEMBL483892 IC50 77.4 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=NC(=O)C(Cc3c[nH]c4ccccc34)N2)cc1 CHEMBL2407733 IC50 78.0 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3353925 IC50 78.0 nM
O=C1CC[C@@H](C(=O)N[C@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356919 IC50 78.0 nM
O=C(NO)c1cnc(NC2(c3ccc(F)cc3)CC2)nc1 CHEMBL3655958 IC50 78.0 nM
O=C(CCCCCCNC(=O)c1csc(Br)n1)NO CHEMBL5172507 IC50 78.0 nM
CCCCN(Cc1ccc(C(=O)NNCC)cc1)C(=O)Nc1ccccc1 CHEMBL5192895 IC50 78.0 nM
CN(C)c1ccc(C(=O)N(CC(=O)NC(C)(C)C)Cc2ccc(C(=O)Nc3cc(-c4ccncc4)ccc3N)cc2)cc1 CHEMBL5416731 IC50 78.1 nM
CC(Nc1ncc(C(=O)NO)cn1)c1ccccc1 CHEMBL3655915 IC50 79.0 nM
CC1(NCc2ccc(C(=O)NCc3ccc(/C=C/C(=O)NO)cc3)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5189911 IC50 79.0 nM
Cc1noc(C)c1-c1ccc2c(c1)c(Cc1cccc(C(F)(F)F)c1)cn2CCCCCCC(=O)NO CHEMBL5279294 IC50 79.0 nM
COc1ccc(NCc2ccc(C(=O)Nc3cc(-c4cccs4)ccc3N)cc2)cc1OC CHEMBL237584 IC50 80.0 nM
Cc1cc(C)cc(C(=O)NOCCCCCC(=O)NO)c1 CHEMBL2312168 Ki 80.0 nM
CCN(CC)CCNC(=O)c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 CHEMBL5093179 IC50 80.0 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 Ki 80.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=NC[C@H](c3ccccc3)S2)cc1 CHEMBL2407723 IC50 81.0 nM
CN(C)c1cccc2c(S(=O)(=O)N(CCCCCC(=O)NO)CC(=O)NCc3ccccc3)cccc12 CHEMBL4437165 IC50 81.0 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1cnn(-c2ccc(F)cc2)n1 CHEMBL4644721 IC50 81.0 nM
O=C(CCCCCCCOc1cccc(-c2nc3ccc(-c4nc5ccccc5[nH]4)cc3[nH]2)c1)NO CHEMBL5094029 IC50 81.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=N[C@H](Cc3ccccc3)CS2)cc1 CHEMBL2407721 IC50 82.0 nM
CN(c1ccc(Cl)c(Cl)c1)c1ncc(C(=O)NO)cn1 CHEMBL3652232 IC50 82.0 nM
O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)C1)O2)NO CHEMBL3758901 IC50 82.0 nM
CCNNC(=O)c1ccc(CNc2cccc3cccnc23)cc1 CHEMBL5177971 IC50 82.0 nM
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)OCc4cn(CCCCCCC(=O)NO)nn4)cn1c23 CHEMBL4643070 IC50 82.0 nM
Nc1ccccc1NC(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(Br)cc3)cc2)cc1 CHEMBL5425253 IC50 82.0 nM
Nc1ccccc1NC(=O)c1ccc(COc2ccc(CNC(=O)[C@H]3CCCN3Cc3ccccc3)cc2)cc1 CHEMBL5408299 IC50 83.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCOCC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645825 IC50 83.1 nM
Cc1cc(C)cc(C(=O)N(CCCCCC(=O)NO)CC(=O)NC2CCCCC2)c1 CHEMBL4095934 IC50 84.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=N[C@@H](c3ccccc3)CS2)cc1 CHEMBL2407717 IC50 85.0 nM
Cc1cc(-c2nc3sc4c(c3c(=O)[nH]2)CCN(C)C4)cc(C)c1OCCOCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL4465878 IC50 85.0 nM
Nc1ccccc1NC(=O)c1ccc(CNc2nc(-c3ccccc3)cs2)cc1 CHEMBL5266056 IC50 85.0 nM
COc1cc2c(cc1-c1c(C)noc1C)[nH]c1nc(C)nc(NCCCCCCC(=O)NO)c12 CHEMBL5422534 IC50 85.0 nM
N[C@@H](CCCCCC(=O)c1ccon1)c1ccn(-c2ccc(F)cc2)n1 CHEMBL4641904 IC50 86.0 nM
O=C(/C=C/c1ccc(CN2C/C(=N\O)c3cc(Cl)ccc32)cc1)NO CHEMBL5286638 IC50 86.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(C(=O)Nc3cc(C(F)(F)F)ccn3)cc2OC)[nH]1 CHEMBL4755946 IC50 87.0 nM
CCCC[C@H](NC(=O)[C@H](C)c1c(C)[nH]c2ccc(O)cc12)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4861270 IC50 87.0 nM
O=C(NO)c1ccc(CN2C(=O)/C(=C3\Nc4ccccc4\C3=N/O)c3cccc(Cl)c32)cc1 CHEMBL4762257 IC50 88.0 nM
CCNNC(=O)c1ccc(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(OC)cc2)cc1 CHEMBL4104334 IC50 88.77 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098695 IC50 89.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098689 IC50 89.0 nM
O=C(CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1)NO CHEMBL3098691 IC50 89.0 nM
CCOc1ccc(CN2CCN(c3ncc(C(=O)NO)cn3)CC2)cc1-c1nc2c(CC)nn(C)c2c(=O)[nH]1 CHEMBL3923840 IC50 89.0 nM
O=C(NO)c1ccc(NC(=O)[C@@H](NC(=O)c2cccc(Br)c2)c2ccccc2)cc1 CHEMBL5273740 IC50 89.2 nM
Cn1c(=O)ccc2cc(C(=O)NCCCCCCC(=O)NO)ccc21 CHEMBL3309284 IC50 90.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSCCS)OC1=O CHEMBL4078721 IC50 90.0 nM
COc1cc(C(=O)NOCCCCCC(=O)NO)cc(OC)c1OC CHEMBL4643795 Ki 90.0 nM
Cn1c(SCCCCCC(=O)NO)nnc1-c1ccncc1 CHEMBL4857970 IC50 90.0 nM
C[C@@H](c1ccc(C(=O)Nc2ccc(F)cc2N)cc1)n1nc(-c2ccc(CN(C)C)cc2)ccc1=O CHEMBL5409244 IC50 90.0 nM
COc1cc2nc(-c3ccc(C)o3)cc(NCc3ccc(C(=O)NO)cc3)c2cc1OC CHEMBL4863394 IC50 91.0 nM
O=C(CCCCCCCOc1cccc(-c2nc3ccccc3[nH]2)c1)NO CHEMBL5077171 IC50 91.0 nM
CCC(=O)CCCCCC(NC(=O)c1cncs1)c1[nH]c(-c2ccccc2)nc1C(=O)NC CHEMBL4782188 IC50 91.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3cccnc3c2)[nH]1 CHEMBL4759915 IC50 92.0 nM
O=C(CCCCCONC(=O)c1ccc2ccccc2n1)NO CHEMBL4866536 IC50 92.0 nM
CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)cc1 CHEMBL511749 IC50 93.0 nM
Cc1ccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)cc1 CHEMBL3098606 IC50 93.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NCCCCCCC(=O)NO)cc21 CHEMBL3311473 IC50 93.0 nM
CC(C)C[C@H](C(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1)c1ccccc1 CHEMBL3907413 IC50 93.0 nM
C#Cc1nc(C(=O)NCCCCCCC(=O)NO)cs1 CHEMBL5209294 IC50 93.0 nM
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)/C=C/c2cccnc2)cc1 CHEMBL3621988 IC50 93.28 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=NC[C@H](c3ccccc3)O2)cc1 CHEMBL3605503 IC50 94.0 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@H](/C(F)=C/CCS)OC1=O CHEMBL4574424 IC50 95.51 nM
O=C(NO)c1cnc(NC2(c3cc(F)cc(F)c3)CC2)nc1 CHEMBL3656001 IC50 96.0 nM
CC(Nc1ncc(C(=O)NO)cn1)c1ccncc1 CHEMBL3655962 IC50 96.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccccc2F)nc1C#N CHEMBL4746267 IC50 96.0 nM
C=CC(=O)Nc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2cc1OCc1cn(CCCC(=O)NO)nn1 CHEMBL4794670 IC50 96.0 nM
O=C(CCCCCCCNc1nn2c(=O)c3cc(F)ccc3nc2c2ccccc12)NO CHEMBL5072785 IC50 96.0 nM
O=C(NO)c1cnc(NCCc2cccc(Cl)c2)nc1 CHEMBL3655925 IC50 97.0 nM
Cc1cc(-c2nc3sc4c(c3c(=O)[nH]2)CCN(C)C4)cc(C)c1OCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL4548155 IC50 97.0 nM
COc1cc(OC)c2c(N3CCN(C)CC3)nc(-c3cc(C)c(OCCCCCC(=O)NO)c(C)c3)nc2c1 CHEMBL4781177 IC50 97.32 nM
Nc1ccccc1NC(=O)c1ccc(NC(=O)c2n[nH]cc2NC(=O)c2c(Cl)cccc2Cl)cc1 CHEMBL5417235 IC50 98.75 nM
O=C(NO)c1ccc(CN2C(=O)c3cccc4c(N5CCOCC5)ccc(c34)C2=O)cc1 CHEMBL4176291 IC50 98.8 nM
CCCCCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4789519 IC50 99.56 nM