OC1(c2ccccc2)C=C(c2ccccc2)CO1 CHEMBL5270048 IC50 -50000.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCCN2C1=O CHEMBL5413269 Ki 0.04 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4860000 IC50 0.06 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3ccc(C)nc3cc2OC)o1 CHEMBL4862152 IC50 0.08 nM
CN1CC(C(=O)N[C@@H](CCCCCC(=O)c2ccon2)c2ncc(-c3ccccc3F)[nH]2)C1 CHEMBL4641682 IC50 0.087 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4649205 IC50 0.093 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC1CC1)CC2)c1ncc(-c2cc3cccnc3cc2OC)[nH]1 CHEMBL4861467 IC50 0.1 nM
Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 Ki 0.1 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(c(OC)cc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4878197 IC50 0.13 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL343448 Ki 0.15 nM
C=C1CN(Cc2ccc(C(=O)Nc3ccccc3N)cc2)C(=O)c2ccccc21 CHEMBL4294949 IC50 0.16 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644038 IC50 0.18 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4642518 IC50 0.19 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc3nc(C)ccc3c2)nc1C#N CHEMBL4759693 IC50 0.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cn(C)c3ccccc23)[nH]1 CHEMBL4742026 IC50 0.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3[nH]c4ccccc4c3c2)[nH]1 CHEMBL4780309 IC50 0.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C(C)C)ccc2OC)[nH]1 CHEMBL4753460 IC50 0.2 nM
O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)NO CHEMBL99392 Ki 0.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637357 IC50 0.24 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL430060 Ki 0.26 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638264 IC50 0.28 nM
CCCNNC(=O)/C=C/c1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL4597954 IC50 0.28 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(OC)ccc3o2)cc1 CHEMBL5093099 IC50 0.28 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSCC/C=C/[C@@H]2CC(=O)NCc3nc(cs3)C3=N[C@@](C)(CS3)C(=O)N[C@@H](C(C)C)C(=O)O2)OC1=O CHEMBL3329621 IC50 0.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc3nn(C)cc3c2)nc1C#N CHEMBL4761973 IC50 0.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(-c3cccnc3)cc2)nc1C#N CHEMBL4746782 IC50 0.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3ccccc3c2)[nH]1 CHEMBL4745088 IC50 0.3 nM
C[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)NC(=O)[C@@H](C)NC1=O CHEMBL279636 Ki 0.3 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCOCCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4869000 IC50 0.32 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(C)ccc3c2)[nH]1 CHEMBL5218556 IC50 0.33 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCC(N(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4642023 IC50 0.34 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(CC)ccc3c2)[nH]1 CHEMBL5219006 IC50 0.34 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3cccnc3cc2OC)[nH]1 CHEMBL5218586 IC50 0.36 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccncc3nc2OC)[nH]1 CHEMBL5219039 IC50 0.37 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1ccc(O)cc1)NC2=O CHEMBL3317811 IC50 0.38 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3o2)cc1 CHEMBL5078985 IC50 0.38 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 IC50 0.4 nM
CCOC(=O)c1cc2cc(OC)c(-c3cnc([C@H](CCCCCC(=O)CC)NC(=O)[C@H]4CC45CCN(CC)CC5)[nH]3)cc2o1 CHEMBL4758559 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)ccc2OC)[nH]1 CHEMBL4759606 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(N4CCCC4)ccc3c2)[nH]1 CHEMBL5220616 IC50 0.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccc(=O)n(C)c3cc2OC)o1 CHEMBL5220454 IC50 0.4 nM
[11CH3]n1cc(CCNCc2ccc(/C=C/C(=O)NO)cc2)c2ccccc21 CHEMBL5288006 IC50 0.4 nM
COc1cc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL4278715 IC50 0.41 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(OC)ccc3c2)[nH]1 CHEMBL5219634 IC50 0.41 nM
CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)cc1 CHEMBL511749 IC50 0.42 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(N4CCCC4)nc3cc2OC)[nH]1 CHEMBL4861271 IC50 0.42 nM
CC(C)(C)OC(=O)Nc1ccc(-c2cc(NC(=O)CCCCCCC(=O)NO)no2)cc1 CHEMBL4876454 IC50 0.42 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3[nH]2)cc1 CHEMBL5083249 IC50 0.44 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)cc2)[nH]1 CHEMBL5219739 IC50 0.45 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3ccncc3)cc2)[nH]1 CHEMBL5218926 IC50 0.46 nM
CC(=O)Nc1ccc(C(=O)Nc2ccccc2N)cc1 CHEMBL235191 K 0.46 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3310505 K 0.47 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccncc3nc2OC)o1 CHEMBL5219490 IC50 0.49 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 Ki 0.5 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(O)ccc3o2)cc1 CHEMBL5086141 IC50 0.51 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(-c4ncco4)ccc3c2)[nH]1 CHEMBL5219359 IC50 0.51 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nn(C)cc3c2)[nH]1 CHEMBL5219969 IC50 0.54 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2CC)[nH]1 CHEMBL5220254 IC50 0.54 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3s2)cc1 CHEMBL5087431 IC50 0.55 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(OC)ccc3[nH]2)cc1 CHEMBL5080511 IC50 0.58 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCSSC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)OC1=O CHEMBL3329622 IC50 0.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4648704 IC50 0.6 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL2448576 IC50 0.6 nM
CCC(=O)CCCCC[C@H](NC(=O)C(C)(C)N(C)C)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5269165 IC50 0.6 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Cl)ccc3o2)cc1 CHEMBL5089712 IC50 0.62 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Br)ccc3o2)cc1 CHEMBL5083475 IC50 0.62 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3ncccc3c2)[nH]1 CHEMBL5218535 IC50 0.63 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1 CHEMBL5087971 IC50 0.66 nM
O=C(CCCCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621294 IC50 0.669 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(-c3ccccc3)[nH]c2=O)[nH]1 CHEMBL5219338 IC50 0.67 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1ccccc1)NC2=O CHEMBL3317810 IC50 0.68 nM
CC(C)[C@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL1796689 IC50 0.7 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593247 IC50 0.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4785376 IC50 0.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2c(F)cccc2OC)[nH]1 CHEMBL4755945 IC50 0.7 nM
CCOC(=O)C1CC1c1ccc(OC)c(-c2cnc([C@H](CCCCCC(=O)CC)NC(=O)[C@H]3CC34CCN(CC)CC4)[nH]2)c1 CHEMBL4788187 IC50 0.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C(F)(F)F)ccc2OC)[nH]1 CHEMBL4747553 IC50 0.7 nM
Cc1ccc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc1 CHEMBL4288953 IC50 0.75 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cnccn3)cc2)[nH]1 CHEMBL5219422 IC50 0.75 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1cccnc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4639206 IC50 0.78 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cccnc2)cc1)NO CHEMBL3759794 IC50 0.8 nM
COc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4237803 Ki 0.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638330 IC50 0.8 nM
CCC(=O)CCCCC[C@H](NC(=O)CC1CC2(C1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4638976 IC50 0.8 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(F)ccc3o2)cc1 CHEMBL5093836 IC50 0.83 nM
C=CCOc1ccc2oc(C(=O)NCc3ccc(C(=O)NNCCC)cc3)cc2c1 CHEMBL5089744 IC50 0.85 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(C/C=C/CN2C4CCC2c2cc(ccc24)-c2cnc1[nH]2)CC3 CHEMBL4854377 IC50 0.86 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccccc3c2)cc1 CHEMBL5084347 IC50 0.89 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1C[C@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644118 IC50 0.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4748244 IC50 0.9 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccccc3n2)cc1 CHEMBL5073909 IC50 0.9 nM
CCNNC(=O)c1ccc(CNC(=O)Nc2cccc3cccnc23)cc1 CHEMBL5189990 IC50 0.9 nM
CCCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4526892 IC50 0.95 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)c1 CHEMBL3356916 IC50 1.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nc(-n4cccn4)ccc3c2)[nH]1 CHEMBL5220720 IC50 1.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3cnccc3c2)cc1 CHEMBL5075150 IC50 1.03 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](Cc1c[nH]cn1)NC2=O CHEMBL3317812 IC50 1.1 nM
CC(C)(C)OC(=O)n1cnc(C[C@@H]2NC(=O)[C@]3(C)CSC(=N3)c3csc(n3)CNC(=O)C[C@@H](/C=C/CCS)OC2=O)c1 CHEMBL3317818 IC50 1.1 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5271471 IC50 1.1 nM
COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 CHEMBL3759059 IC50 1.2 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CC2(C1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4641343 IC50 1.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1C[C@@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4634829 IC50 1.2 nM
CCC(=O)CCCCC[C@H](NC(=O)C1=NOC2(CCN(C)CC2)C1)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4633758 IC50 1.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(ccc(=O)n3C)c2)[nH]1 CHEMBL5218980 IC50 1.2 nM
COc1cccc(-c2nc(NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)c1 CHEMBL4285608 IC50 1.3 nM
CCOC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4464421 IC50 1.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2F)o1 CHEMBL5220408 IC50 1.3 nM
CCCNNC(=O)c1ccc(CNC(=O)c2nc3ccccc3s2)cc1 CHEMBL5084847 IC50 1.31 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(Br)ccc3[nH]2)cc1 CHEMBL5076715 IC50 1.31 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3cc(F)cc(F)c3)nn2)c1)NO CHEMBL1091815 IC50 1.4 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccccn2)cc1)NO CHEMBL3758870 IC50 1.4 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-c3cccnc3)nc2)[nH]1 CHEMBL4754237 IC50 1.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)cc(F)c2OC)[nH]1 CHEMBL4794196 IC50 1.4 nM
CCCNNC(=O)c1ccc(CNC(=O)c2nc3ccccc3[nH]2)cc1 CHEMBL5081353 IC50 1.44 nM
C[C@@H]1CN(C(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cnn(CCCCCCC(=O)NO)c4n3)cc2)CCO1 CHEMBL4532398 IC50 1.47 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccccc3cn2)cc1 CHEMBL5086924 IC50 1.48 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 Ki 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4636652 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCC2(CC1)CN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637745 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC12CCN(CC)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4646582 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC(F)(F)F)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4632432 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(F)c(F)cc2OC)[nH]1 CHEMBL4793832 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(OC)nc2OC)[nH]1 CHEMBL4754365 IC50 1.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C)nc3cc2Cl)[nH]1 CHEMBL5218651 IC50 1.5 nM
Nc1ccc(-n2cc(-c3cccc(NC(=O)CCCCCCC(=O)NO)c3)nn2)cc1 CHEMBL1094708 IC50 1.55 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3ccncc3c2)cc1 CHEMBL5075425 IC50 1.55 nM
COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(=O)NO)C(=O)NCCc3c(-c4ccccc4)[nH]c4ccccc34)c2c1 CHEMBL216641 IC50 1.6 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cccs2)cc1)NO CHEMBL3758735 IC50 1.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4640923 IC50 1.6 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cc3cc(F)ccc3[nH]2)cc1 CHEMBL5089258 IC50 1.61 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccc(O)cc3)nn2)c1)NO CHEMBL1088735 IC50 1.66 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL4550526 IC50 1.7 nM
CCCN1CCC2(CC1)C[C@@H]2C(=O)N[C@@H](CCCCCC(=O)CC)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4640939 IC50 1.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1ccc(OC)cc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4647014 IC50 1.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(C)nc2OC)[nH]1 CHEMBL4748516 IC50 1.7 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@H](C)CC)NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL443392 IC50 1.7 nM
CCC(=O)CCCCC[C@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](Cc2cn(OC)c3ccccc23)NC1=O CHEMBL4873847 IC50 1.7 nM
CCCNNC(=O)c1ccc(CNC(=O)c2cnc3ccccc3c2)cc1 CHEMBL5073024 IC50 1.79 nM
CC(C)(C)OC(=O)NCCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3317817 IC50 1.8 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccncc2)cc1)NO CHEMBL3758281 IC50 1.8 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 1.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1C[C@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645468 IC50 1.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4759472 IC50 1.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccnc2OC)[nH]1 CHEMBL4753639 IC50 1.8 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 IC50 1.8 nM
COc1ccc(/C=N/NC(=O)CCCCCCCC(=O)NO)cc1 CHEMBL5269123 IC50 1.82 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(C(F)(F)F)cc2)nc1C#N CHEMBL4797893 IC50 1.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(F)c2OC)[nH]1 CHEMBL4751762 IC50 1.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cc3ccc(C4CC4)nc3cc2F)o1 CHEMBL5219978 IC50 1.9 nM
CC(C)(C)OC(=O)Nc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 CHEMBL2417782 IC50 2.0 nM
O=C(CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(C(F)(F)F)c1)NO CHEMBL3098602 IC50 2.0 nM
O=C1NC[C@@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356925 IC50 2.0 nM
O=C(CCCCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3759921 IC50 2.0 nM
O=C(NO)c1ccc(Cn2cc(-c3ccc(CN4CCCC4)cc3)nn2)cc1 CHEMBL4090165 IC50 2.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc4ccccc4c3)CCOCC2)cc1 CHEMBL4642874 IC50 2.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(-c4cn[nH]c4)cc3)CCCCC2)cc1 CHEMBL4639966 IC50 2.0 nM
CC(C)[C@H](N)C(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL5314582 IC50 2.0 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccc3cnccc3n2)cc1 CHEMBL5074837 IC50 2.03 nM
Nc1cccc(-c2csc(NC(=O)CCCCCC(=O)NO)n2)c1 CHEMBL1630208 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4637397 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCOCC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4649561 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(Cc1ccccc1)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4644387 IC50 2.1 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(C2=CC3SC=NC3C=C2)[nH]1 CHEMBL5220815 IC50 2.2 nM
CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(C(=O)NO)cc2)cc1 CHEMBL4798826 IC50 2.25 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc(C#N)ccc2OC)[nH]1 CHEMBL4797791 IC50 2.3 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL27759 IC50 2.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(C2=CC3OC=NC3C=C2)[nH]1 CHEMBL5221068 IC50 2.3 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cn(C)nc3cc2OC)o1 CHEMBL5218487 IC50 2.3 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2ccnc(c2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593411 IC50 2.31 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2cncnc2)cc1)NO CHEMBL3758492 IC50 2.4 nM
CCC(=O)CCCCC[C@H](NC(=O)C12CCN(CC1)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4741084 IC50 2.4 nM
Nc1ccccc1NC(=O)CCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2 CHEMBL3621297 IC50 2.42 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL4649628 IC50 2.5 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1[nH]c(-c2ccccc2)nc1C(N)=O CHEMBL4776685 IC50 2.5 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccc(F)cc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4443998 IC50 2.54 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)NC1=O CHEMBL3593407 IC50 2.59 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C(C)=O)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4636123 IC50 2.6 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCOCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4876610 IC50 2.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3nccnc3cc2OC)[nH]1 CHEMBL5220576 IC50 2.6 nM
O=C(CCCCCN1C(=O)c2cccc3c(N4CCOCC4)ccc(c23)C1=O)NO CHEMBL4160632 IC50 2.65 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(CC(O)c3cccc(Br)c3)nn2)c1)NO CHEMBL483893 IC50 2.7 nM
O=C(/C=C/C#Cc1ccc(NS(=O)(=O)c2ccccc2)cc1)NO CHEMBL314389 Ki 2.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(Cl)c2OC)[nH]1 CHEMBL4753648 IC50 2.7 nM
O=C(C=C1c2ccccc2-c2ccccc21)NCCCCCC(=O)NO CHEMBL485514 IC50 2.8 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(-c3ccccc3)nn2)c1)NO CHEMBL1094709 IC50 2.8 nM
O=C(/C=C/c1cccc(S(=O)(=O)N2CCN(c3ccccn3)CC2)c1)NO CHEMBL1958424 ED50 2.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1C[C@@]12CCN(C)C2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4641048 IC50 2.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4788911 IC50 2.9 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc([N+](=O)[O-])ccc2OC)[nH]1 CHEMBL4757813 IC50 2.9 nM
Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1 CHEMBL3339024 IC50 2.92 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(I)cc3)nn2)c1)NO CHEMBL1091475 IC50 3.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 Ki 3.0 nM
O=C1NCCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356527 IC50 3.0 nM
Cc1ccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCCC(=O)N2)cc1 CHEMBL3356917 IC50 3.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 CHEMBL3356923 IC50 3.0 nM
C[C@H](NC(=O)c1nc(-c2ncc(-c3ccccc3)s2)sc1C1CC1)c1ccc(C(=O)NO)cc1 CHEMBL4460552 IC50 3.02 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2cccc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3593409 IC50 3.07 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CCC(F)(F)F)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4643947 IC50 3.1 nM
CCC(=O)CCCCC[C@H](NC(=O)c1cncs1)c1[nH]c(-c2ccc(F)cc2)nc1C#N CHEMBL4760209 IC50 3.1 nM
O=C(NO)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 CHEMBL4750701 IC50 3.13 nM
COc1ccc(C(=O)N[C@H](COc2ccc(/C=C/C(=O)NO)cc2)Cc2c[nH]c3ccccc23)cc1 CHEMBL3233705 IC50 3.2 nM
CN(C)c1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1F CHEMBL3339029 IC50 3.22 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3cc(CO)cc(CO)c3)nn2)c1)NO CHEMBL1088736 IC50 3.3 nM
COc1cc(-n2cc(-c3cccc(NC(=O)CCCCCCC(=O)NO)c3)nn2)ccc1F CHEMBL1076939 IC50 3.39 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccc(C(F)(F)F)cc3)nn2)c1)NO CHEMBL1088734 IC50 3.4 nM
O=C(CCCCCC(=O)N/N=C/c1ccc(-c2ccccc2)cc1)NO CHEMBL3759982 IC50 3.4 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CCOCC1)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4796175 IC50 3.4 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(C(=O)NC3CCOC3)cc2)[nH]1 CHEMBL4761389 IC50 3.4 nM
O=C(CCCCc1nnc(-c2cc3c([nH]c4ccccc43)c(-c3ccc(C(F)(F)F)cc3)n2)o1)NO CHEMBL5187023 IC50 3.4 nM
CN(CCc1ccccc1)S(=O)(=O)c1cccc(/C=C/C(=O)NO)c1 CHEMBL5274004 IC50 3.4 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccccc3)ncnc2s1)NO CHEMBL3339022 IC50 3.47 nM
CCCNNC(=O)c1ccc(CNC(=O)c2ccccc2)cc1 CHEMBL4740035 IC50 3.47 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc(-n3nc(C)cc3C)cc2)[nH]1 CHEMBL4756846 IC50 3.5 nM
CCN(CC)c1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1F CHEMBL3339028 IC50 3.52 nM
COc1ccc2[nH]cc(CCNC(=O)c3ccc(/C=C/C(=O)NO)cc3)c2c1 CHEMBL5090786 pIC50 3.548 nM
Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCCC(=O)NO)cc23)cc1C CHEMBL3339026 IC50 3.56 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(O[C@H]4CCOC4)c(Cl)c3)ncnc2s1)NO CHEMBL3339030 IC50 3.58 nM
CCC(=O)CCCCC[C@H](NC(=O)C1CN(C)C1)c1[nH]c(-c2ccc(F)cc2)nc1C(N)=O CHEMBL4781191 IC50 3.6 nM
COc1cc(-c2nc(-c3nnc(CCCCC(=O)NO)o3)cc3c2[nH]c2ccccc23)cc(OC)c1OC CHEMBL5192364 IC50 3.6 nM
CCCCNNC(=O)c1ccc(CNC(=O)/C=C/c2ccccc2)cc1 CHEMBL4757047 IC50 3.67 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2cc3ccccc3[nH]2)cc1)NO CHEMBL403323 IC50 3.7 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(C3CCCCC3)nn2)c1)NO CHEMBL1094707 IC50 3.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCC(N(C)C)CC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645863 IC50 3.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3c(c2)C2CCC3C2)[nH]1 CHEMBL4859950 IC50 3.7 nM
CC(C)(C)c1ccc(CC(=O)Nc2ccc(C(=O)NO)cc2)cc1 CHEMBL4755724 IC50 3.74 nM
COc1ccc(-c2cnc(-c3nc(C(=O)N[C@@H](C)c4ccc(C(=O)NO)cc4)c(C4CC4)s3)s2)cc1 CHEMBL4450360 IC50 3.78 nM
O=C(CCCCCCn1cc(Nc2ncc3ccn(Cc4ccccc4F)c3n2)cn1)NO CHEMBL5076728 IC50 3.8 nM
Cc1[nH]c2ccccc2c1C1=CCC(NCc2ccc(OCC(=O)NO)cc2F)CC1 CHEMBL5185310 IC50 3.8 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2cnc3ncccc3c2)[nH]1 CHEMBL5219241 IC50 3.8 nM
O=C(/C=C/c1ccc(OC[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(Cl)cc2)cc1)NO CHEMBL3233698 IC50 3.9 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccc(F)cc3)nn2)c1)NO CHEMBL483892 IC50 4.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@@H]2CCC(=O)N2)c1 CHEMBL3356922 IC50 4.0 nM
Cc1ccc(Nc2nccc3ccc(NC(=O)CCCCCCC(=O)NO)cc23)cc1 CHEMBL3601333 IC50 4.0 nM
O=C(NO)c1ccc(NC(=O)C2(c3ccc(Br)cc3)CCOCC2)cc1 CHEMBL4634521 IC50 4.0 nM
Nc1cccc(-c2cc(C(=O)NCCCCCCC(=O)NO)no2)c1 CHEMBL468595 IC50 4.04 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 Ki 4.1 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2CC(O)c2cccc(Br)c2)c1)NO CHEMBL487107 IC50 4.2 nM
CC(C)(C)OC(=O)NCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL3317816 IC50 4.2 nM
Nc1ccc(-c2nc(N3CCOCC3)c3cnn(CCCCCCC(=O)NO)c3n2)cc1 CHEMBL4552057 IC50 4.21 nM
O=C(CCCN1CCN(C(=O)Nc2cccc3ncccc23)CC1)NO CHEMBL5268663 IC50 4.42 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2Cc2ccccc2)c1)NO CHEMBL488747 IC50 4.5 nM
CCC(=O)CCCCCC(NC(=O)c1cncs1)c1[nH]c(-c2ccccc2)nc1C(=O)NCCN(C)C CHEMBL4761318 IC50 4.5 nM
Nc1nc2cc(-c3nn(CCCCCCC(=O)NO)c4ncnc(N)c34)ccc2o1 CHEMBL4846560 IC50 4.6 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nnccc3c2)[nH]1 CHEMBL5219074 IC50 4.6 nM
CCC(=O)CCCCCC(NC(=O)c1cncs1)c1[nH]c(-c2ccccc2)nc1C(=O)NC CHEMBL4782188 IC50 4.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc(Cl)cc2OC)[nH]1 CHEMBL4781134 IC50 4.7 nM
CCCC[C@H](NC(=O)[C@H](CN)c1c(C)[nH]c2ccc(O)cc12)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4867665 IC50 4.7 nM
C/C=C1\NC(=O)[C@@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL146250 IC50 4.8 nM
O=C(/C=C/c1ccc(Cl)cc1F)NCCCCCC(=O)NO CHEMBL484489 IC50 4.9 nM
O=C1CC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3353925 IC50 5.0 nM
O=C1NCCC[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356915 IC50 5.0 nM
O=C1CC[C@@H](C(=O)N[C@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356919 IC50 5.0 nM
Cc1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2C)c1 CHEMBL3356924 IC50 5.0 nM
Cc1noc(C)c1-c1ccc2c(c1)c(Cc1ccc(F)cc1)cn2CCCCCCC(=O)NO CHEMBL4454646 IC50 5.0 nM
COC(c1c(F)cccc1Cl)c1c[nH]c2ncc(-c3c(C)noc3C)cc12 CHEMBL4752855 IC50 5.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cc3cn(C)nc3cc2OC)[nH]1 CHEMBL5221097 IC50 5.0 nM
Cc1noc(C)c1-c1ccc2c(c1)C(Cc1ccc(F)cc1)CN2CCCCCCC(=O)NO CHEMBL5290597 IC50 5.0 nM
Cc1ccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)cc1 CHEMBL3970532 Ki 5.0 nM
COc1ccc2[nH]cc(CCNCc3ccc(/C=C/C(=O)NO)cc3)c2c1 CHEMBL141502 IC50 5.1 nM
Cc1[nH]c2ccccc2c1CCNS(=O)(=O)c1ccc(/C=C/C(=O)NO)cc1 CHEMBL3329991 IC50 5.13 nM
Cn1cc(CN2CC3(CCN(c4ncc(C(=O)NO)cn4)C3)C2)c2ccc(C#N)cc21 CHEMBL5093798 IC50 5.2 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2ccc3ccncc3c2)[nH]1 CHEMBL5220120 IC50 5.2 nM
O=C(/C=C/c1ccc(S(=O)(=O)Nc2cc(F)cc(F)c2)cc1)NO CHEMBL5283395 IC50 5.2 nM
CC(/C=C/c1ccccc1)=C\C(=O)NCCCCCC(=O)NO CHEMBL490018 IC50 5.3 nM
O=C(CCCCCCC(=O)Nc1cccc(-n2cc(C3CCCCC3)nn2)c1)NO CHEMBL1094710 IC50 5.3 nM
Cc1ccccc1-c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 CHEMBL3758191 IC50 5.4 nM
O=C(CCCCCCC(=O)Nc1ccc2ccnc(Nc3ccc4ccccc4c3)c2c1)NO CHEMBL3601334 IC50 5.42 nM
O=C(/C=C/c1ccc(OC[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(F)cc2)cc1)NO CHEMBL3233703 IC50 5.5 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC12CCOCC2)c1ncc(-c2cc3ccccc3nc2OC)[nH]1 CHEMBL4645825 IC50 5.5 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2Cc2ccc(F)cc2)c1)NO CHEMBL487106 IC50 5.8 nM
COc1ccccc1NC(=O)N[C@H](C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 CHEMBL5284956 IC50 5.9 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H]([C@H](C)CC)NC(=O)[C@H](Cc2cn(CC(=O)NCCCCCCNC(=O)CCSSCCNC(=O)C(CCCCNC(=O)CCCCC3SCC4NC(=O)NC43)NC(=O)c3ccc(N=[N+]=[N-])cc3)c3ccccc23)NC1=O CHEMBL1791401 IC50 6.0 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCCN)NC2=O CHEMBL3317815 IC50 6.0 nM
O=C1CCC[C@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356524 IC50 6.0 nM
Nc1nn(-c2ccccc2)nc1C(=O)NCc1ccc(C(=O)NO)cc1 CHEMBL5415232 IC50 6.0 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1ncc(-c2ccc3nccnc3c2)[nH]1 CHEMBL5219811 IC50 6.2 nM
O=C(COc1ccc(CNCCc2c[nH]c3ccccc23)c(F)c1)NO CHEMBL5185297 IC50 6.3 nM
O=C(CCCCCCc1nc2ccc(Br)cc2[nH]1)NO CHEMBL2414098 IC50 6.4 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3cccc(Cl)c3)ncnc2s1)NO CHEMBL3339020 IC50 6.46 nM
O=C(/C=C/c1ccc2cccnc2c1)NCCCCCC(=O)NO CHEMBL484073 IC50 6.7 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(CC)CC2)c1ncc(-c2cccc(C(F)(F)F)c2OC)[nH]1 CHEMBL4794888 IC50 6.7 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2ccccc2)cc1)NO CHEMBL512644 IC50 7.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc3cc(F)ccc3n2)nc1 CHEMBL1801250 IC50 7.0 nM
CN1C(=O)CCC[C@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356526 IC50 7.0 nM
O=C(O)c1cccc(-c2ccc(C3(C(=O)Nc4ccc(C(=O)NO)cc4)CCCC3)cc2)c1 CHEMBL4640415 IC50 7.0 nM
CCC(=O)CCCCC[C@H](NC(=O)N1CCOCC1)c1ncc(-c2cc3ccccc3nc2OC)o1 CHEMBL5281406 IC50 7.0 nM
COc1ccc(C(=O)N[C@H](COc2ccc(/C=C/C(=O)NO)cc2OC)Cc2c[nH]c3ccccc23)cc1 CHEMBL4070891 IC50 7.1 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCOCCn2ccc4cc(ccc4c2=O)-c2cnc1[nH]2)CC3 CHEMBL4853593 IC50 7.1 nM
CNC(=O)CCCCCCCn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21 CHEMBL4870348 IC50 7.1 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(-c3ccccc3)nn2)c1)NO CHEMBL519668 IC50 7.2 nM
CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2coc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O CHEMBL2436595 IC50 7.2 nM
CCCC(CCC)C(=O)N[C@H](COc1ccc(/C=C/C(=O)NO)cc1OC)Cc1c[nH]c2ccccc12 CHEMBL2336043 IC50 7.5 nM
O=C(N[C@@H](CCCCNC(=O)c1c(O)cccc1F)c1ncc(-c2ccc3ccccc3c2)[nH]1)c1cncs1 CHEMBL4753111 IC50 7.6 nM
C/C=C1\NC(=O)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622729 IC50 7.67 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2-c2ccccc2)c1)NO CHEMBL520056 IC50 7.7 nM
C[C@@]12CSC(=N1)c1csc(n1)CNC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](CCN)NC2=O CHEMBL3317814 IC50 7.8 nM
O=C(CCCCCCC(=O)Nc1cccc(-c2cn(Cc3ccccc3)nn2)c1)NO CHEMBL483693 IC50 7.9 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cn(-c3ccccc3)nn2)cc1)NO CHEMBL519491 IC50 8.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 8.0 nM
O=C(CCCCCCC(=O)Nc1cccnc1)NO CHEMBL353581 Ki 8.0 nM
O=C1C[C@@H](C(=O)N[C@@H](CCCCCS)C(=O)Nc2ccccc2)N1 CHEMBL3356929 IC50 8.0 nM
O=C(NO)c1cnc(NC2(c3c(F)cccc3F)CC2)nc1 CHEMBL3655993 IC50 8.0 nM
CC(C)C[C@H]1CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCCC(=O)NO)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N1 CHEMBL585939 IC50 8.0 nM
Cc1ccc2nc3c4ccccc4c(NCCCCCCC(=O)NO)nn3c(=O)c2c1 CHEMBL5091856 IC50 8.17 nM
O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(N4CCCCC4)c(F)c3)ncnc2s1)NO CHEMBL3339031 IC50 8.19 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 Ki 8.2 nM
O=C(NO)c1ccc(NC(=O)[C@@H](NC(=O)c2cccc(Br)c2)c2ccccc2)cc1 CHEMBL5273740 IC50 8.5 nM
CCCCNNC(=O)c1ccc(CNC(=O)c2ccccc2)cc1 CHEMBL4787271 IC50 8.56 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 9.0 nM
CC(C)(C)c1[nH]c2ccccc2c1[C@H]1CCCN(Cc2ccc(/C=C/C(=O)NO)cc2F)C1 CHEMBL1093033 IC50 9.0 nM
O=C1NC[C@H](c2ccccc2)[C@@H]1C(=O)N[C@@H](CCCCCS)C(=O)Nc1ccccc1 CHEMBL3356927 IC50 9.0 nM
CCC(=O)CCCCC[C@@H]1NC(=O)[C@@H](C)n2nncc2[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL2012817 IC50 9.0 nM
CN(C)c1ccc(C2(C(=O)Nc3ccc(C(=O)NO)cc3)CCCC2)cc1 CHEMBL4636734 IC50 9.0 nM
CCCCCCCC(=O)SCC/C=C/[C@@H]1CC(=O)NCc2nc(cs2)C2=N[C@@](C)(CS2)C(=O)N[C@@H](C(C)C)C(=O)O1 CHEMBL1173445 IC50 9.09 nM
C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL598797 IC50 9.1 nM
O=C(CCCCCCNc1nn2c(=O)c3ccccc3nc2c2ccccc12)NO CHEMBL5087773 IC50 9.18 nM
Nc1cccc(F)c1C(=O)NCCCC[C@H](NC(=O)c1cncs1)c1ncc(-c2ccc3ccccc3c2)[nH]1 CHEMBL4749183 IC50 9.3 nM
Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCC(=O)NO)cc23)cc1 CHEMBL3339023 IC50 9.33 nM
O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)CC1)O2)NO CHEMBL1938433 IC50 9.4 nM
COc1cc([C@@H]2c3cc4c(cc3[C@@H](Nc3cccc(OCCCCCCC(=O)NO)c3)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O CHEMBL2442801 IC50 9.6 nM
O=C(CCCCCCC(=O)Nc1ccc(-c2cnnn2Cc2ccccc2)cc1)NO CHEMBL519746 IC50 9.7 nM
O=C(CCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621296 IC50 9.77 nM
C/C=C1\NC(=O)c2csc(n2)[C@@H](C(C)C)NC(=O)C[C@@H](/C=C/CCS)OC(=O)[C@H](C(C)C)NC1=O CHEMBL3622727 IC50 9.77 nM
CCC(=O)CCCCC[C@H](NC(=O)[C@H]1CC12CCN(C)CC2)c1nnc(-c2cc3ccccc3nc2OC)o1 CHEMBL4644657 IC50 9.9 nM