Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 Ki 0.7 nM
C[C@H](CN(C)Cc1ccccc1)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL3692689 IC50 1.2 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 Ki 2.1 nM
Cc1cccc(C(=O)NOCCCCCC(=O)NO)c1 CHEMBL2312164 IC50 2.31 nM
O=C(CCCCCCc1nc2ccc(Br)cc2[nH]1)NO CHEMBL2414098 IC50 2.5 nM
CC/C=C\CCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830536 Ki 3.1 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc(-c2cnco2)cc1 CHEMBL3110021 IC50 4.0 nM
Cc1cc(C)cc(C(=O)NOCCCCCC(=O)NO)c1 CHEMBL2312168 IC50 4.22 nM
CCCN(CCC)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL3692671 IC50 5.0 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 IC50 5.58 nM
CCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830537 Ki 5.6 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 IC50 6.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830422 Ki 6.6 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830420 Ki 6.8 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc2nccnc2c1 CHEMBL3110001 IC50 7.0 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 7.1 nM
O=C(/C=C/c1ccc2cccnc2c1)NCCCCCC(=O)NO CHEMBL484073 IC50 7.6 nM
O=C(NO)c1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1-c1ccccc1 CHEMBL4761013 IC50 8.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc2c(c1)CN(CC(F)(F)F)C2=O CHEMBL3109983 IC50 9.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1cc(Cl)c2c(c1)OCCO2 CHEMBL3109980 IC50 9.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(C)C CHEMBL1830424 Ki 9.2 nM
O=C(c1ccc(-c2nc(COc3ccc(-c4nnco4)cc3)no2)s1)C(F)(F)F CHEMBL518821 IC50 10.0 nM
O=C(NO)[C@]1(F)[C@H](c2ccccc2)[C@H]1c1ccc(-c2ncc(F)cn2)cc1 CHEMBL3793392 IC50 10.0 nM
Cn1c(CCCC(=O)O)nc2cc(N(CCCl)CCCl)ccc21 CHEMBL487253 IC50 10.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830396 Ki 11.0 nM
CN(C)CC(C)(C)Cn1c(CC(C)(C)C)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL1830397 Ki 11.0 nM
C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL598797 IC50 11.4 nM
O=C(NO)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1-c1ccccc1 CHEMBL4748500 IC50 12.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 13.0 nM
CN(C)CC(C)(C)Cn1c(CCc2ccccc2)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL460963 Ki 16.0 nM
Cc1ncc(-c2ccc(C(C(=O)NO)c3ccccc3F)cc2)cn1 CHEMBL4437833 IC50 16.0 nM
O=C(NO)c1ccc(CN2C(=O)c3cccc(F)c3C2=O)cc1-c1ccccc1 CHEMBL4799406 IC50 16.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCC1)NO CHEMBL491316 Ki 17.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCCC1)NO CHEMBL489332 Ki 18.0 nM
C[C@H](CN1CCC[C@@H]1C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL4798111 IC50 20.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL3215861 Ki 21.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL1851943 Ki 21.0 nM
O=C(NO)c1cnc(N2CCN(C(/C=C/c3ccc(F)cc3)CO)CC2)nc1 CHEMBL594544 IC50 21.8 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 Ki 25.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccnc(C2CC2)c1 CHEMBL3109993 IC50 30.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc(-c2ncc(F)cn2)cc1 CHEMBL3110015 IC50 30.0 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 Ki 33.0 nM
Cc1ccc(C(=O)NOCCCCCC(=O)NO)cc1C CHEMBL2312167 IC50 33.4 nM
O=C(CCCCCCC(=O)C(F)(F)F)Nc1ccccc1 CHEMBL113537 IC50 40.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccccc1)NO CHEMBL1083439 Ki 46.0 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 IC50 48.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1cccc(-c2ncc(F)cn2)c1 CHEMBL3110016 IC50 50.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631913 IC50 55.4 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)Nc3ccccn3)cc2)cc1 CHEMBL3670669 IC50 60.0 nM
O=C(NO)C(c1ccc(-c2ncc(C(F)(F)F)cn2)cc1)c1ccccc1F CHEMBL4456445 IC50 60.0 nM
O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL4879105 IC50 61.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631914 IC50 62.2 nM
O=C(NCC1(c2nc(-c3ccccc3)cs2)CCOCC1)c1cccc(-c2noc(C(F)(F)F)n2)c1 CHEMBL3110004 IC50 80.0 nM
O=C(NO)C(c1cccc(F)c1)c1cccc(F)c1 CHEMBL574594 IC50 90.0 nM
O=C(NCCN1CCCC1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL4747488 IC50 90.0 nM
[11CH3]n1cc(CCNCc2ccc(/C=C/C(=O)NO)cc2)c2ccccc21 CHEMBL5288006 IC50 99.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631917 IC50 109.0 nM
O=C(NO)C(c1ccc2c(c1)CCO2)c1ccc2c(c1)CCO2 CHEMBL583967 IC50 110.0 nM
O=C(NO)C1c2ccccc2Oc2ccccc21 CHEMBL583490 IC50 110.0 nM
N=C1Sc2ccccc2C2=NCCCN12 CHEMBL595227 IC50 110.0 nM
O=C(CCCCCCN(c1ccccn1)c1ccc2ccccc2n1)NO CHEMBL3675758 IC50 123.0 nM
COc1ccc(COC(CCCCCC(=O)NO)C(=O)Nc2ccccc2)cc1 CHEMBL251011 IC50 134.0 nM
O=C(CCCCCC(c1c[nH]c2ccc([N+](=O)[O-])cc12)c1c[nH]c2ccc([N+](=O)[O-])cc12)NO CHEMBL561604 IC50 140.0 nM
O=C(NO)C(c1ccccc1)c1ccccc1 CHEMBL396097 IC50 140.0 nM
CCCN(CCCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL5172806 IC50 140.0 nM
CC(C)(CNC(=O)c1cccc(-c2noc(C(F)(F)F)n2)c1)c1coc(-c2ccccc2)n1 CHEMBL4751615 IC50 147.9 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631918 IC50 150.0 nM
Cn1cc([C@H]2[C@H](C(=O)NO)[C@@H]2c2ccccc2)cn1 CHEMBL3110023 IC50 150.0 nM
O=C(NO)C1c2ccccc2-c2ccccc21 CHEMBL3110003 IC50 150.0 nM
COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1/C=C/C(=O)Nc1ccccc1N CHEMBL4874942 IC50 150.0 nM
CCCN(CCCCOCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL5208515 IC50 150.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631915 IC50 155.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)NCCS)cc2)cc1 CHEMBL3670668 IC50 172.0 nM
O=C(/C=C/c1ccc(C(=O)N/N=C/c2ccc(O)c(O)c2O)cc1)NO CHEMBL1213457 Ki 180.0 nM
CN1CCC(CNC(=O)c2cccc(-c3noc(C(F)(F)F)n3)c2)(c2nc(-c3ccccc3)cs2)CC1 CHEMBL4525406 Ki 182.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc3cc(F)ccc3n2)nc1 CHEMBL1801250 IC50 200.0 nM
Cc1nc2ccccc2n1Cc1ccc(C(=O)NO)cc1F CHEMBL4080014 IC50 200.0 nM
O=C(NO)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 CHEMBL572805 IC50 210.0 nM
O=C(NO)c1ccc(Cn2c(=O)[nH]c(=O)c3cccc(Cl)c32)cc1 CHEMBL5438457 IC50 211.0 nM
COc1ccc(-c2cc(-c3ccoc3)c(C(=O)NCc3ccc(C(=O)NO)cc3)[nH]2)cc1 CHEMBL4087897 IC50 220.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccsc3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670674 IC50 222.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC(F)(F)c2cnc(-c3ccc(C(C(=O)NO)c4ccccc4F)cc3)nc2)C(C)(C)C)cc1 CHEMBL5194487 IC50 230.0 nM
CCCN(CCCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL5199458 IC50 250.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC(F)(F)c2cnc(-c3ccc(C(C(=O)NO)c4ccccc4F)cc3)nc2)C(C)(C)C)cc1 CHEMBL5181194 IC50 260.0 nM
NC(=O)c1ccc2c(c1)CCCN2Cc1ccc(C(=O)NO)cc1 CHEMBL4846435 IC50 276.0 nM
O=C(NO)C(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL573190 IC50 280.0 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 IC50 300.0 nM
CC(C)(C)Nc1c(-c2cccc(-c3nc4cc(-c5noc(C(F)(F)F)n5)ccc4[nH]3)c2)nc2cnccn12 CHEMBL4861149 IC50 306.9 nM
O=C(CCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NO CHEMBL227118 IC50 310.0 nM
CC(C)(C)Nc1c(-c2cccc(-c3nc4cc(-c5noc(C(F)(F)F)n5)ccc4[nH]3)c2)nc2ccccn12 CHEMBL4862147 IC50 310.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCC(F)(F)c2cnc(-c3ccc(C(C(=O)NO)c4ccccc4F)cc3)nc2)C(C)(C)C)cc1 CHEMBL5202426 IC50 310.0 nM
COc1cccc2c(C(CCCCCC(=O)NO)c3c[nH]c4c(OC)cccc34)c[nH]c12 CHEMBL561483 IC50 311.0 nM
O=C(NO)C1[C@H](c2ccccc2)[C@H]1c1ccccc1 CHEMBL3110005 IC50 340.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OCCC2 CHEMBL1631916 IC50 341.0 nM
O=C(/C=C/c1ccc(/C=C(/CNC2CC2)c2ccc(F)cc2)cc1)NO CHEMBL3758457 IC50 354.0 nM
CC(C)(CCCCC(=O)NO)Nc1c(Nc2ccc(C(F)(F)F)cc2)c(=O)c1=O CHEMBL4241370 Ki 360.0 nM
CN(C)c1cccc2c(SNCCCCCC(=O)NO)cccc12 CHEMBL5271192 IC50 370.0 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)S(=O)(=O)CC3)cc1 CHEMBL4069287 IC50 400.0 nM
O=C(NO)c1ccc(CN2c3ccccc3C3C2CCS3(=O)=O)cc1 CHEMBL4445312 IC50 400.0 nM
CN(C)c1cccc2c(S(=O)(=O)NCCCCCC(=O)NO)cccc12 CHEMBL4759256 IC50 400.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 406.0 nM
O=C(NO)c1ccc(Nc2c3ccccc3nc3ccc(OCc4ccccc4)cc23)cc1 CHEMBL4761847 IC50 430.0 nM
CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(NCc3ccc(C(=O)NO)cn3)c2c(=O)n1-c1ccccc1 CHEMBL4443548 IC50 439.0 nM
O=C(CCCCCCN(c1ccccn1)c1ccccn1)NO CHEMBL3675757 IC50 458.0 nM
CN1c2ccccc2C(C(=O)NO)c2ccccc21 CHEMBL572545 IC50 470.0 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827894 IC50 484.0 nM
O=C(NO)c1cnc(N2C[C@@H]3[C@H](C2)[C@H]3NCc2ccc(Cl)cc2)nc1 CHEMBL1801238 IC50 500.0 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)CS(=O)(=O)CC3)cc1 CHEMBL4577299 IC50 500.0 nM
O=C(NO)c1ccc(Cn2c3c(c4cc(F)ccc42)CS(=O)(=O)CC3)cc1 CHEMBL4531108 IC50 500.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(F)c2)c1 CHEMBL5436104 IC50 500.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 IC50 532.0 nM
Cc1ccc(CN2CCC(c3noc(CN(C)c4ncc(C(=O)NO)cn4)n3)CC2)cc1 CHEMBL4517151 IC50 540.0 nM
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O CHEMBL343448 Ki 550.0 nM
O=C(CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12)NO CHEMBL564876 IC50 590.0 nM
O=C(/C=C/c1ccc(CNc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1)NO CHEMBL5205415 IC50 617.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccc(O)cc3)cc2-c2ccoc2)cc1 CHEMBL3670675 IC50 640.0 nM
COc1cc(OC)c2c(N3CCS(=O)(=O)CC3)nc(-c3cc(C)c(OCCCCCC(=O)NO)c(C)c3)nc2c1 CHEMBL4790998 IC50 688.4 nM
O=C(NO)c1ccc(Nc2c3ccccc3nc3ccc(F)cc23)cc1 CHEMBL4757035 IC50 690.0 nM
O=C(CCCCCC1OCCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631912 IC50 695.0 nM
O=C(NO)c1cc(F)c(Cn2nnnc2-c2cccs2)c(F)c1 CHEMBL4862563 IC50 699.0 nM
CN1C(=O)C2CN(Cc3c2c2ccccc2n3Cc2ccc(C(=O)NO)cc2)C1=O CHEMBL4087616 Ki 701.0 nM
CN(Cc1nc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc2n1C)c1ncc(C(=O)NO)cn1 CHEMBL3827814 IC50 750.0 nM
CC(C)(C)Nc1c(-c2ccc(-c3noc(C(F)(F)F)n3)cc2)nc2ccccn12 CHEMBL4854692 IC50 812.1 nM
O=C(CCCCCCC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2)NO CHEMBL3621294 IC50 850.0 nM
O=C(NO)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1 CHEMBL4762873 IC50 850.0 nM
O=C(CCCCCC1OCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631911 IC50 878.0 nM
O=C(CS)NCCCCCC(=O)Nc1cccc2cccnc12 CHEMBL178456 IC50 890.0 nM
[N-]=[N+]=NCc1cc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc(N=[N+]=[N-])c1 CHEMBL1914708 IC50 892.0 nM
[N-]=[N+]=NCc1cc(N=[N+]=[N-])cc(C(=O)Nc2ccc(-c3cc(C(=O)NCCCCCCC(=O)NO)no3)cc2)c1 CHEMBL1914702 IC50 932.0 nM
O=C(NO)c1ccc(Cn2sc3ccccc3c2=O)cc1 CHEMBL5185889 IC50 940.0 nM
COc1ccc(Nc2c(NCCCCCC(=O)NO)c(=O)c2=O)cc1 CHEMBL4237803 Ki 1000.0 nM
CN1CCc2c(c3ccccc3n2Cc2ccc(C(=O)NO)cc2)C1 CHEMBL2018302 IC50 1000.0 nM