Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 CHEMBL27759 IC50 0.5 nM
C[C@H](CN(C)Cc1ccccc1)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL3692689 IC50 0.9 nM
O=C(CCCCCCc1nc2ccc(Br)cc2[nH]1)NO CHEMBL2414098 IC50 1.1 nM
Cc1[nH]c2ccccc2c1CCNCc1ccc(/C=C/C(=O)NO)cc1 CHEMBL483254 Ki 1.2 nM
O=C(C=C1c2ccccc2-c2ccccc21)NCCCCCC(=O)NO CHEMBL485514 IC50 2.3 nM
CC(C)(CNC(=O)c1cccc(-c2noc(C(F)(F)F)n2)c1)c1coc(-c2ccccc2)n1 CHEMBL4751615 IC50 2.4 nM
O=C(/C=C/c1ccc2cccnc2c1)NCCCCCC(=O)NO CHEMBL484073 IC50 2.8 nM
Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21 CHEMBL2105763 Ki 3.8 nM
O=C(/C=C/c1ccc(Cl)cc1F)NCCCCCC(=O)NO CHEMBL484489 IC50 3.9 nM
CC(/C=C/c1ccccc1)=C\C(=O)NCCCCCC(=O)NO CHEMBL490018 IC50 4.2 nM
CCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830537 Ki 4.4 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@H](/C=C/C(=O)NO)CC3)cc21 CHEMBL3309297 IC50 5.2 nM
CC/C=C\CCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830536 Ki 5.7 nM
O=C(CCCCCNC(=O)NC(=O)c1ccc(Br)cc1)NO CHEMBL1083086 Ki 6.0 nM
CN1CCC(CNC(=O)c2cccc(-c3noc(C(F)(F)F)n3)c2)(c2nc(-c3ccccc3)cs2)CC1 CHEMBL4525406 Ki 8.0 nM
O=C(/C=C/c1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1)NO CHEMBL356066 IC50 8.24 nM
CCCN(CCC)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL3692671 IC50 10.0 nM
O=C(NCC1(c2nc(-c3ccccc3)cs2)CCOCC1)c1cccc(-c2noc(C(F)(F)F)n2)c1 CHEMBL3110004 IC50 10.0 nM
CN(C)CC(C)(C)Cn1c(CC(C)(C)C)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL1830397 Ki 11.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(C)C CHEMBL1830424 Ki 11.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNCC CHEMBL1830420 Ki 14.0 nM
CCCCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830422 Ki 16.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCC1)NO CHEMBL491316 Ki 19.0 nM
CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1 CHEMBL99 IC50 20.0 nM
O=C(CCCCCCC(=O)Nc1ccccc1)NO CHEMBL98 IC50 20.0 nM
O=C(c1ccc(-c2nc(COc3ccc(-c4nnco4)cc3)no2)s1)C(F)(F)F CHEMBL518821 IC50 20.0 nM
O=C(NO)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1-c1ccccc1 CHEMBL4748500 IC50 20.0 nM
CN(C)CC(C)(C)Cn1c(CCc2ccccc2)nc2cc(/C=C/C(=O)NO)ccc21 CHEMBL460963 Ki 21.0 nM
O=C(/C=C/c1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCCCC1)NO CHEMBL489332 Ki 24.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL3215861 Ki 24.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO CHEMBL408513 Ki 24.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCN(CC)CC CHEMBL1851943 Ki 24.0 nM
O=C(CCCCCCC(=O)Nc1ccc2c(c1)CCC(=O)N2)NO CHEMBL3311465 IC50 25.0 nM
COc1ccc(NS(=O)(=O)c2cccc(/C=C/C(=O)NO)c2)cc1 CHEMBL1958439 ED50 26.0 nM
O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1 CHEMBL609583 IC50 28.0 nM
CCCCc1nc2cc(/C=C/C(=O)NO)ccc2n1CCNC(C)C CHEMBL1830396 Ki 30.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc2nccnc2c1 CHEMBL3110001 IC50 30.0 nM
Cc1ncc(-c2ccc(C(C(=O)NO)c3ccccc3F)cc2)cn1 CHEMBL4437833 IC50 30.0 nM
C[C@H](CN1CCC[C@@H]1C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL4798111 IC50 30.0 nM
COc1ccc2cc(C(=O)NCCCCCCC(=O)NO)ccc2n1 CHEMBL3309288 IC50 34.0 nM
O=C(CCCCCCNC(=O)c1ccc2c(c1)CCC(=O)N2)NO CHEMBL3311472 IC50 35.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NCc3ccc(/C=C/C(=O)NO)cc3)cc21 CHEMBL3309291 IC50 37.0 nM
[N-]=[N+]=NCc1cc(N=[N+]=[N-])cc(C(=O)Nc2ccc(-c3cc(C(=O)NCCCCCCC(=O)NO)no3)cc2)c1 CHEMBL1914702 IC50 37.8 nM
O=C(NO)c1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1-c1ccccc1 CHEMBL4761013 IC50 38.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NCCCCCCC(=O)NO)cc21 CHEMBL3311473 IC50 39.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc(-c2cnco2)cc1 CHEMBL3110021 IC50 40.0 nM
O=C(NO)c1cnc(N2CCN(C(/C=C/c3ccc(F)cc3)CO)CC2)nc1 CHEMBL594544 IC50 40.7 nM
Cn1c(=O)ccc2cc(C(=O)NCCCCCCC(=O)NO)ccc21 CHEMBL3309284 IC50 41.0 nM
Cc1ccc(-c2csc(NC(=O)CCCCCCS)n2)cc1 CHEMBL3288475 IC50 42.0 nM
CC1(C)CC(=O)Nc2ccc(NC(=O)CCCCCCC(=O)NO)cc21 CHEMBL3311466 IC50 45.0 nM
O=C(CCCCCCNC(=O)c1ccc2[nH]c(=O)ccc2c1)NO CHEMBL3311471 IC50 46.0 nM
O=C(NO)c1ccc(CN2C(=O)c3cccc(F)c3C2=O)cc1-c1ccccc1 CHEMBL4799406 IC50 46.0 nM
O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL4879105 IC50 48.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1cc(Cl)c2c(c1)OCCO2 CHEMBL3109980 IC50 50.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@@H](CCC(=O)NO)CC3)cc21 CHEMBL3309300 IC50 50.0 nM
O=C(NO)C(c1ccc(-c2ncc(C(F)(F)F)cn2)cc1)c1ccccc1F CHEMBL4456445 IC50 50.0 nM
O=C(CCCCCNC(=O)NC(=O)c1ccccc1)NO CHEMBL1083439 Ki 55.0 nM
O=C(CCCCCCS)Nc1nc(-c2ccc(F)cc2)cs1 CHEMBL3288489 IC50 57.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@H](CCC(=O)NO)CC3)cc21 CHEMBL3309298 IC50 57.0 nM
O=C(CCCCCCC(=O)Nc1ccc2[nH]c(=O)ccc2c1)NO CHEMBL3311464 IC50 58.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)Nc3ccccn3)cc2)cc1 CHEMBL3670669 IC50 59.0 nM
O=C(NO)[C@]1(F)[C@H](c2ccccc2)[C@H]1c1ccc(-c2ncc(F)cn2)cc1 CHEMBL3793392 IC50 60.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631914 IC50 60.6 nM
Cc1ccc(-c2csc(NC(=O)CCCCCCS)n2)cc1F CHEMBL3288488 IC50 62.0 nM
C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCC(=O)NO)cc23)c1 CHEMBL598797 IC50 67.2 nM
Cc1nc2ccccc2n1Cc1ccc(C(=O)NO)cc1F CHEMBL4080014 IC50 70.0 nM
O=C(NCCN1CCCC1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL4747488 IC50 70.0 nM
O=C(CCCCCCS)Nc1nc(-c2cccc(F)c2)cs1 CHEMBL3288484 IC50 78.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc2c(c1)CN(CC(F)(F)F)C2=O CHEMBL3109983 IC50 80.0 nM
O=C(CCCCCCS)Nc1nc(-c2ccccc2)cs1 CHEMBL419758 IC50 82.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)N2CCN(c3ccccn3)CC2)c1)NO CHEMBL1958424 ED50 86.0 nM
O=C(CCCCCCN(c1ccccn1)c1ccc2ccccc2n1)NO CHEMBL3675758 IC50 90.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NC[C@H]3CC[C@@H](/C=C/C(=O)NO)CC3)cc21 CHEMBL3309299 IC50 91.0 nM
CCCN(CCCCOCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL5208515 IC50 94.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631913 IC50 99.6 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)S(=O)(=O)CC3)cc1 CHEMBL4069287 IC50 100.0 nM
O=C(/C=C/c1cccc(S(=O)(=O)Nc2cccc(F)c2)c1)NO CHEMBL1958436 ED50 109.0 nM
O=C(NO)C1c2ccccc2-c2ccccc21 CHEMBL3110003 IC50 120.0 nM
CN1C(=O)CC(C)(C)c2cc(C(=O)NCCCCCCC(=O)NO)ccc21 CHEMBL3309286 IC50 120.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631917 IC50 123.0 nM
CCCN(CCCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL5172806 IC50 130.0 nM
COc1ccccc1N1CCN(S(=O)(=O)c2cccc(/C=C/C(=O)NO)c2)CC1 CHEMBL1958433 ED50 145.0 nM
O=C(CCCCCCN(c1ccccn1)c1cc2ccccc2cn1)NO CHEMBL3675764 IC50 145.0 nM
O=C(CCCCCC(c1c[nH]c2ccc([N+](=O)[O-])cc12)c1c[nH]c2ccc([N+](=O)[O-])cc12)NO CHEMBL561604 IC50 150.0 nM
COc1ccc(-c2cc(-c3ccoc3)c(C(=O)NCc3ccc(C(=O)NO)cc3)[nH]2)cc1 CHEMBL4087897 IC50 160.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccsc3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670674 IC50 163.0 nM
CN(C)Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2ccccc12 CHEMBL2103863 IC50 168.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc(-c2ncc(F)cn2)cc1 CHEMBL3110015 IC50 190.0 nM
O=C(NO)c1ccc(CN2c3ccccc3C3C2CCS3(=O)=O)cc1 CHEMBL4445312 IC50 200.0 nM
CCCN(CCCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C)C[C@@H](C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 CHEMBL5199458 IC50 220.0 nM
COc1ccc(COC(CCCCCC(=O)NO)C(=O)Nc2ccccc2)cc1 CHEMBL251011 IC50 247.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccnc(C2CC2)c1 CHEMBL3109993 IC50 260.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)NCCS)cc2)cc1 CHEMBL3670668 IC50 277.0 nM
O=C(/C=C/c1nc2ccccc2o1)NO CHEMBL1958440 ED50 278.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC(F)(F)c2cnc(-c3ccc(C(C(=O)NO)c4ccccc4F)cc3)nc2)C(C)(C)C)cc1 CHEMBL5194487 IC50 290.0 nM
O=C(NO)c1ccc(Cn2c3c(c4ccccc42)CS(=O)(=O)CC3)cc1 CHEMBL4577299 IC50 300.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OC/C=C\2 CHEMBL1631915 IC50 302.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)[C@@H](CCCCCC(=O)NO)OCCC2 CHEMBL1631918 IC50 322.0 nM
COc1cc2cc(c1)COc1ccccc1NC(=O)C(CCCCCC(=O)NO)OCCC2 CHEMBL1631916 IC50 336.0 nM
COc1cccc2c(C(CCCCCC(=O)NO)c3c[nH]c4c(OC)cccc34)c[nH]c12 CHEMBL561483 IC50 340.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCC(F)(F)c2cnc(-c3ccc(C(C(=O)NO)c4ccccc4F)cc3)nc2)C(C)(C)C)cc1 CHEMBL5202426 IC50 340.0 nM
O=C(NO)c1ccc(CN2c3ccccc3Sc3ccc(Cl)cc32)cc1 CHEMBL4530950 IC50 350.0 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2Cc1ccc(C(=O)NO)cc1 CHEMBL5076794 IC50 362.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1cccc(-c2ncc(F)cn2)c1 CHEMBL3110016 IC50 370.0 nM
COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1/C=C/C(=O)Nc1ccccc1N CHEMBL4874942 IC50 370.0 nM
CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1 CHEMBL1213492 Ki 390.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC(F)(F)c2cnc(-c3ccc(C(C(=O)NO)c4ccccc4F)cc3)nc2)C(C)(C)C)cc1 CHEMBL5181194 IC50 420.0 nM
O=C(CCCCCCN(c1ccccn1)c1cc(OCc2ccccc2)ccn1)NO CHEMBL3675765 IC50 423.0 nM
O=C(NO)c1ccc(Cn2c(=O)[nH]c(=O)c3cccc(Cl)c32)cc1 CHEMBL5438457 IC50 431.0 nM
Cc1ccc(CN2CCC(c3noc(CN(C)c4ncc(C(=O)NO)cn4)n3)CC2)cc1 CHEMBL4517151 IC50 441.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccc(O)cc3)cc2-c2ccoc2)cc1 CHEMBL3670675 IC50 478.0 nM
O=C(NO)c1cc(F)c(Cn2nnc(-c3ncccn3)n2)c(F)c1 CHEMBL4470373 IC50 480.0 nM
O=C(NO)c1ccc(Cn2c3c(c4cc(F)ccc42)CS(=O)(=O)CC3)cc1 CHEMBL4531108 IC50 500.0 nM
O=C(NO)c1ccc(Cn2c3c(c4cc(F)ccc42)C[S+]([O-])CC3)cc1 CHEMBL4283105 IC50 500.0 nM
O=C(CCCCCCC(=O)Nc1ccc([C@H]2O[C@@H](CSc3nc(-c4ccccc4)c(-c4ccccc4)o3)C[C@@H](c3ccc(CO)cc3)O2)cc1)NO CHEMBL356769 Ki 509.3 nM
O=C(NO)C(c1ccccc1)c1ccccc1 CHEMBL396097 IC50 510.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)c1ccc2c(ccn2Cc2ccc(C(=O)NO)c(F)c2)c1 CHEMBL5436104 IC50 510.0 nM
O=C(NO)c1ccc(Nc2c3ccccc3nc3ccc(F)cc23)cc1 CHEMBL4757035 IC50 520.0 nM
COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 CHEMBL3622533 IC50 554.0 nM
CC1(C)CC(=O)Nc2ccc(C(=O)NCc3cccc(/C=C/C(=O)NO)c3)cc21 CHEMBL3309290 IC50 570.0 nM
O=C(NO)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1 CHEMBL4762873 IC50 570.0 nM
NC(=O)c1ccc2c(c1)N(Cc1ccc(C(=O)NO)cc1)c1ccccc1S2 CHEMBL4862510 IC50 590.0 nM
CN1CCc2c(c3ccccc3n2Cc2ccc(C(=O)NO)cc2)C1 CHEMBL2018302 IC50 621.0 nM
O=C(CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12)NO CHEMBL564876 IC50 640.0 nM
NC(=O)c1ccc2c(c1)CCCN2Cc1ccc(C(=O)NO)cc1 CHEMBL4846435 IC50 650.0 nM
O=C(NO)c1cc(F)c(Cn2nnnc2-c2cccs2)c(F)c1 CHEMBL4862563 IC50 658.0 nM
O=C(CCCCCC1OCCCCCCOc2ccccc2NC1=O)NO CHEMBL1631911 IC50 687.0 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NO CHEMBL96051 IC50 700.0 nM
O=C(NO)c1ccc(CN2CCCc3cccnc32)c(F)c1 CHEMBL5401750 IC50 701.0 nM
[N-]=[N+]=NCc1cc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc(N=[N+]=[N-])c1 CHEMBL1914708 IC50 704.0 nM
CSc1ccc2c(c1)N(Cc1ccc(C(=O)NO)cc1)c1ccccc1[S+]2[O-] CHEMBL4872697 IC50 720.0 nM
O=C(NO)c1ccc(CN2c3ccccc3Sc3ccc(C(=O)Nc4ccccn4)cc32)cc1 CHEMBL4852441 IC50 730.0 nM
COc1ccc(N(CCCCCCC(=O)NO)c2ccccn2)nc1 CHEMBL3675763 IC50 759.0 nM
Cc1ccc(N(CCCCCCC(=O)NO)c2ccccn2)nc1 CHEMBL3675761 IC50 759.0 nM
Cn1cc([C@H]2[C@H](C(=O)NO)[C@@H]2c2ccccc2)cn1 CHEMBL3110023 IC50 790.0 nM
O=C(NO)c1ccc(Cn2c3c(c4cc(F)ccc42)CSCC3)cc1 CHEMBL4537561 IC50 800.0 nM
CC(C)(C)Nc1c(-c2cccc(-c3nc4cc(-c5noc(C(F)(F)F)n5)ccc4[nH]3)c2)nc2ccccn12 CHEMBL4862147 IC50 818.0 nM
O=C(NO)c1ccc(CN2c3ccccc3Sc3ccc(C(=O)Nc4ccc(Br)cn4)cc32)cc1 CHEMBL4874716 IC50 850.0 nM
Cc1ccc(NC(=O)c2ccc3c(c2)N(Cc2ccc(C(=O)NO)cc2)c2ccccc2S3)nc1 CHEMBL4861336 IC50 900.0 nM
O=C(/C=C/c1ccc(/C=C(/CNC2CC2)c2ccc(F)cc2)cc1)NO CHEMBL3758457 IC50 927.0 nM
CC(=O)N1c2ccc(-c3ccccc3)cc2[C@H](NC(=O)CCCCCCC(=O)NO)C[C@@H]1C CHEMBL3220924 IC50 930.0 nM