Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1cccc(Cl)c1 CHEMBL3342603 Ki 10.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)c(Br)c1 CHEMBL3343183 Ki 11.0 nM
Cc1cccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)c1 CHEMBL3342605 Ki 13.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1cccc(Br)c1 CHEMBL3342604 Ki 14.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccccc1F CHEMBL3342432 Ki 15.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Br)cc1 CHEMBL3342610 Ki 18.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccccc1 CHEMBL3342431 Ki 19.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1cccc(F)c1 CHEMBL3342602 Ki 20.0 nM
CCn1c(=O)n(CC)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408320 IC50 21.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Cl)cc1 CHEMBL3342609 Ki 22.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccccc1Cl CHEMBL3342598 Ki 22.0 nM
CCn1c(=O)n(C)c2ccc(C(=O)c3cnn(C)c3O)cc21 CHEMBL3408314 IC50 22.0 nM
CCCn1c(=O)n(CC)c2ccc(C(=O)c3cnn(C)c3O)cc21 CHEMBL3408319 IC50 22.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccccc1Br CHEMBL3342599 Ki 24.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Cl)c(Cl)c1 CHEMBL3343184 Ki 25.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)cc1 CHEMBL3342611 Ki 25.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1cccc(OC(F)(F)F)c1 CHEMBL3342607 Ki 31.0 nM
Cc1cc(Cl)ccc1-n1c(C)nc2ccc(C(=O)c3cnn(C)c3O)cc2c1=O CHEMBL3342614 Ki 32.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(F)cc1 CHEMBL3342608 Ki 34.0 nM
COc1cccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)c1 CHEMBL3342606 Ki 34.0 nM
O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL1337 Ki 37.0 nM
COc1ccccc1-n1c(C)nc2ccc(C(=O)c3cnn(C)c3O)cc2c1=O CHEMBL3342601 Ki 38.0 nM
CCCn1c(=O)n(CC)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408324 IC50 39.0 nM
Cc1cc(F)ccc1-n1c(C)nc2ccc(C(=O)c3cnn(C)c3O)cc2c1=O CHEMBL3343182 Ki 40.0 nM
CCCn1c(=O)n(CCC)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408325 IC50 40.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Br)cc2)c1[N+](=O)[O-] CHEMBL4533679 IC50 47.0 nM
Cc1ccccc1-n1c(C)nc2ccc(C(=O)c3cnn(C)c3O)cc2c1=O CHEMBL3342600 Ki 58.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)c(C)c1 CHEMBL3343187 Ki 59.0 nM
CCCn1c(=O)n(C)c2ccc(C(=O)c3cnn(C)c3O)cc21 CHEMBL3408157 IC50 59.0 nM
COc1ccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)cc1 CHEMBL3342612 Ki 60.0 nM
CC(C)n1c(=O)n(C)c2ccc(C(=O)c3cnn(C)c3O)cc21 CHEMBL3408313 IC50 61.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Cl)cc2Cl)c1[N+](=O)[O-] CHEMBL4526579 IC50 63.0 nM
CCn1c(=O)n(C(C)C)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408321 IC50 64.0 nM
CCC(=O)C(C(C)=O)C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL3408156 IC50 68.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Br)cc2F)c1[N+](=O)[O-] CHEMBL4564855 IC50 68.0 nM
Cc1cc(C)cc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2[N+](=O)[O-])c1 CHEMBL4582009 IC50 68.0 nM
CC(C)c1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2[N+](=O)[O-])cc1 CHEMBL4571726 IC50 70.0 nM
Cc1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2[N+](=O)[O-])cc1 CHEMBL4540372 IC50 70.0 nM
Cc1cccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c1 CHEMBL3342416 Ki 74.0 nM
CCCn1c(=O)n(C(C)(C)C)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408326 IC50 77.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccccc3F)c(=O)c2c1 CHEMBL3342415 Ki 79.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c(F)c1 CHEMBL3342426 Ki 81.0 nM
O=C1CCCC(O)=C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL4567229 IC50 85.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccccc3Cl)c(=O)c2c1 CHEMBL3342412 Ki 86.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c(Br)c1 CHEMBL3342428 Ki 87.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)c(Cl)c1 CHEMBL3343186 Ki 90.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3cccc(F)c3)c(=O)c2c1 CHEMBL3342419 Ki 90.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Br)cc2)c1 CHEMBL4554387 IC50 91.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3cccc(Br)c3)c(=O)c2c1 CHEMBL3342418 Ki 93.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(F)cc2F)c1[N+](=O)[O-] CHEMBL4564283 IC50 95.0 nM
Cn1ncc(C(=O)c2ccc3c(c2)n(C(C)(C)C)c(=O)n3C)c1O CHEMBL3408315 IC50 100.0 nM
Cn1ncc(C(=O)c2ccc3c(c2)n(C2CC2)c(=O)n3C)c1O CHEMBL3408318 IC50 100.0 nM
Cc1c(C(=O)C2=C(O)CCCC2=O)ccc(Cl)c1OCc1ccc(F)cc1 CHEMBL4574113 IC50 102.0 nM
CC1CC(=O)C(C(=O)c2cccc(OCc3ccc(Br)cc3F)c2[N+](=O)[O-])=C(O)C1 CHEMBL4539445 IC50 105.0 nM
CC1CC(=O)C(C(=O)c2cccc(OCc3ccc(Cl)cc3Cl)c2[N+](=O)[O-])=C(O)C1 CHEMBL4565020 IC50 106.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c(Cl)c1 CHEMBL3342430 Ki 109.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Br)cc2F)c1 CHEMBL4571011 IC50 121.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(F)cc2)c1[N+](=O)[O-] CHEMBL4577367 IC50 128.0 nM
Cc1c(C(=O)C2=C(O)CCCC2=O)ccc(Cl)c1OCc1ccccc1 CHEMBL4589830 IC50 128.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccc(Br)cc3)c(=O)c2c1 CHEMBL3342422 Ki 130.0 nM
Cn1ncc(C(=O)c2ccc3c(c2)n(C2CCCC2)c(=O)n3C)c1O CHEMBL3408312 IC50 130.0 nM
Cn1ncc(C(=O)c2ccc3c(c2)n(Cc2ccccc2)c(=O)n3C)c1O CHEMBL3408317 IC50 130.0 nM
CC(C)Cn1c(=O)n(C)c2ccc(C(=O)c3cnn(C)c3O)cc21 CHEMBL3408311 IC50 140.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Cl)cc2Cl)c1 CHEMBL4537208 IC50 143.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Cl)cc2F)c1 CHEMBL4549115 IC50 147.0 nM
CCn1c(=O)n(C(C)(C)C)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408322 IC50 150.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)cc1 CHEMBL3342423 Ki 156.0 nM
Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(OC(F)(F)F)cc1 CHEMBL3342613 Ki 160.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c(C)c1 CHEMBL3342425 Ki 161.0 nM
Cc1ccc(COc2cccc(C(=O)C3=C(O)CC(C)CC3=O)c2[N+](=O)[O-])cc1 CHEMBL4564075 IC50 168.0 nM
Cc1ccc(-n2c(C)nc3ccc(C(=O)c4cnn(C)c4O)cc3c2=O)c(F)c1 CHEMBL3343185 Ki 170.0 nM
CCCCn1c(=O)n(C)c2ccc(C(=O)c3cnn(C)c3O)cc21 CHEMBL3408310 IC50 170.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3cccc(Cl)c3)c(=O)c2c1 CHEMBL3342417 Ki 173.0 nM
CC1CC(=O)C(C(=O)c2cccc(OCc3ccc(Br)cc3)c2)=C(O)C1 CHEMBL4582680 IC50 176.0 nM
Cc1cc(Cl)ccc1-n1c(C)nc2ccc(C(=O)c3c(C)nn(C)c3O)cc2c1=O CHEMBL3342429 Ki 177.0 nM
CC1CC(=O)C(C(=O)c2cccc(OCc3ccc(Br)cc3F)c2)=C(O)C1 CHEMBL4538931 IC50 200.0 nM
COc1ccccc1-n1c(C)nc2ccc(C(=O)c3c(C)nn(C)c3O)cc2c1=O CHEMBL3342414 Ki 207.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(Cl)cc2)c1 CHEMBL4539505 IC50 217.0 nM
Cc1cc(F)ccc1-n1c(C)nc2ccc(C(=O)c3c(C)nn(C)c3O)cc2c1=O CHEMBL3342427 Ki 219.0 nM
CCn1c(=O)n(C2CC2)c2cc(C(=O)c3cnn(C)c3O)ccc21 CHEMBL3408323 IC50 220.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccc(Cl)cc3)c(=O)c2c1 CHEMBL3342424 Ki 237.0 nM
COc1ccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)cc1 CHEMBL3342421 Ki 238.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccc(F)cc3)c(=O)c2c1 CHEMBL3342420 Ki 247.0 nM
Cc1ccccc1-n1c(C)nc2ccc(C(=O)c3c(C)nn(C)c3O)cc2c1=O CHEMBL3342413 Ki 248.0 nM
Cc1ccc(-n2c(=O)n(C)c3ccc(C(=O)c4cnn(C)c4O)cc32)cc1 CHEMBL3408316 IC50 250.0 nM
Cc1c(OCc2ccc(Cl)cc2F)cccc1C(=O)C1=C(O)CCCC1=O CHEMBL4541040 IC50 257.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccc(F)cc2)c1 CHEMBL4591004 IC50 264.0 nM
Cc1c(OCc2ccc(Cl)cc2)cccc1C(=O)C1=C(O)CCCC1=O CHEMBL4529209 IC50 266.0 nM
Cc1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2)cc1 CHEMBL4521608 IC50 266.0 nM
Cc1c(OCc2ccc(Br)cc2)cccc1C(=O)C1=C(O)CCCC1=O CHEMBL4518798 IC50 274.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2cccc(F)c2)c1 CHEMBL4561368 IC50 274.0 nM
Cc1c(OCc2cccc(Br)c2)cccc1C(=O)C1=C(O)CCCC1=O CHEMBL4519334 IC50 280.0 nM
Cc1c(OCc2ccc(F)cc2)cccc1C(=O)C1=C(O)CCCC1=O CHEMBL4552681 IC50 302.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccccc2)c1 CHEMBL4547046 IC50 335.0 nM
Cc1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2C)cc1 CHEMBL4533367 IC50 374.0 nM
O=C1CCCC(O)=C1C(=O)c1cccc(OCc2ccccc2F)c1 CHEMBL4514200 IC50 422.0 nM
Cc1c(OCc2ccc(Cl)cc2F)cccc1C(=O)C1=C(O)CC(C)CC1=O CHEMBL4518828 IC50 447.0 nM
CC1(C)CC(=O)C(C(=O)c2cccc(OCc3ccc(Br)cc3)c2)=C(O)C1 CHEMBL4563917 IC50 558.0 nM
CCCCn1c(=O)n(C)c2ccc(C(=O)c3c(C)nn(C)c3O)cc21 CHEMBL3408328 IC50 640.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2c(c1)n(Cc1ccccc1)c(=O)n2C CHEMBL3408335 IC50 670.0 nM
CCCn1c(=O)n(CCC)c2cc(C(=O)c3c(C)nn(C)c3O)ccc21 CHEMBL3408340 IC50 720.0 nM
CCCn1c(=O)n(CC)c2cc(C(=O)c3c(C)nn(C)c3O)ccc21 CHEMBL3408339 IC50 740.0 nM
CCCn1c(=O)n(CC)c2ccc(C(=O)c3c(C)nn(C)c3O)cc21 CHEMBL3408336 IC50 880.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2c(c1)n(C1CCCC1)c(=O)n2C CHEMBL3408330 IC50 930.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2c(c1)n(C(C)C)c(=O)n2C CHEMBL3408331 IC50 940.0 nM
CCn1c(=O)n(CC)c2cc(C(=O)c3c(C)nn(C)c3O)ccc21 CHEMBL3408337 IC50 940.0 nM
CCn1c(=O)n(C)c2ccc(C(=O)c3c(C)nn(C)c3O)cc21 CHEMBL3408332 IC50 970.0 nM
CCn1c(=O)n(C(C)C)c2cc(C(=O)c3c(C)nn(C)c3O)ccc21 CHEMBL3408338 IC50 970.0 nM
Cc1nn(C)c(O)c1C(=O)c1ccc2c(c1)n(C(C)(C)C)c(=O)n2C CHEMBL3408333 IC50 990.0 nM
Cc1ccc(-n2c(=O)n(C)c3ccc(C(=O)c4c(C)nn(C)c4O)cc32)cc1 CHEMBL3408334 IC50 990.0 nM