Cc1cc(OCCN(C)C)nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12 CHEMBL194837 IC50 0.87 nM
CNC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL1627 Ki 1.7 nM
CN(C)Cc1ccc(CSCCNc2nonc2NCCCc2ccccc2)o1 CHEMBL5276441 Ki 2.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1cccc(F)c1 CHEMBL4875600 pKi 2.042 nM
CCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)s1 CHEMBL5207281 pKi 3.02 nM
Clc1ccc2c(c1)CCc1cccnc1C2=C1CCNCC1 CHEMBL1172 AC50 3.3 nM
N/C(=N\C(=O)NCc1ccccc1)NCCCc1nnc(N)s1 CHEMBL5206565 pEC50 3.311 nM
CCCCCNC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL4860528 pKi 4.467 nM
COc1nccnc1[C@H](C)C1=C(CCN(C)C)Cc2cc(F)ccc21 CHEMBL1090526 Ki 4.5 nM
N/C(=N\C(=O)NCCCCCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)s1)NCCCc1nnc(N)s1 CHEMBL5173079 pKi 4.786 nM
N/C(=N\C(=O)NCc1ccccc1)NCCCc1cnc(N)s1 CHEMBL5178472 pEC50 4.898 nM
CCCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)s1 CHEMBL5200771 pKi 5.129 nM
N/C(=N\C(=O)NCCCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)s1)NCCCc1nnc(N)s1 CHEMBL5176229 pKi 5.248 nM
CN1CC2c3ccccc3Oc3ccc(Cl)cc3C2C1 CHEMBL3544974 Ki 5.7 nM
CCCCCNC(=O)/N=C(\N)NCCCc1cnc(N)s1 CHEMBL5183205 pEC50 6.026 nM
N/C(=N\C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 CHEMBL2165642 pEC50 6.166 nM
C[C@@H](NC(=O)/N=C(\N)NCCCc1c[nH]cn1)c1ccccc1 CHEMBL5208722 pKi 6.166 nM
NC(N)=Nc1nc(CSCC/C(N)=N/S(N)(=O)=O)cs1 CHEMBL902 AC50 6.3 nM
C[C@@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)C1CCCCC1 CHEMBL1096431 pEC50 6.457 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)NCCCc2nnc(N)s2)cc1 CHEMBL5180504 pKi 6.457 nM
NCCCCCCCCNC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL5092102 pEC50 7.413 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL2165628 pEC50 7.586 nM
C=C(/N=C(\C)NCCCc1nnc(N)s1)NCCCCCCCCN CHEMBL5094083 pEC50 7.586 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL2165632 pEC50 7.762 nM
CC(NC(=O)/N=C(\N)NCCCc1nnc(N)s1)c1cccc(F)c1 CHEMBL5184911 pKi 8.128 nM
Cc1nc(N)sc1CCCNC(=N)NC(=O)CC(C)C1CCCCC1 CHEMBL1094142 pEC50 9.333 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCc1ccco1 CHEMBL4865965 pKi 10.47 nM
CC(CNC(=O)/N=C(\N)NCCCc1nnc(N)s1)C1CCCCC1 CHEMBL5204599 pEC50 10.72 nM
NCCc1c[nH]cn1 CHEMBL90 Kd 12.2 nM
CCCN[C@H]1CCc2nc(N)sc2C1 CHEMBL301265 Kd 12.2 nM
CCCCCNC(=O)/N=C(\N)Nc1ccc(-c2sc(N)nc2C)cc1 CHEMBL5209081 Kd 12.2 nM
CCCCCNC(=O)/N=C(\N)Nc1cccc(-c2sc(N)nc2C)c1 CHEMBL5204739 Kd 12.2 nM
CCCCCNC(=O)/N=C(\N)NCC1CCc2nc(N)sc2C1 CHEMBL5207206 Kd 12.2 nM
CCCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)o1 CHEMBL5186770 Kd 12.2 nM
Cc1nnc(CCCN/C(N)=N/C(=O)NCCCCCCCCN)s1 CHEMBL5189006 Kd 12.2 nM
NCCCCCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)s1 CHEMBL5176780 Kd 12.2 nM
Cc1nc(N)sc1-c1ccc(N/C(N)=N/C(=O)NC2CCCCC2)cc1 CHEMBL5170276 Kd 12.2 nM
Cc1nc(N)oc1CCCN/C(N)=N/C(=O)NCC(C)C1CCCCC1 CHEMBL5183015 Kd 12.2 nM
Cc1nnc(CCCN/C(N)=N/C(=O)NCC(C)C2CCCCC2)s1 CHEMBL5209479 Kd 12.2 nM
Cc1nc(N)sc1-c1ccc(N/C(N)=N/C(=O)NCC(C)C2CCCCC2)cc1 CHEMBL5205197 Kd 12.2 nM
Cc1nc(N)oc1CCCN/C(N)=N/C(=O)NCc1ccccc1 CHEMBL5197548 Kd 12.2 nM
Cc1nnc(CCCN/C(N)=N/C(=O)NCc2ccccc2)s1 CHEMBL5175558 Kd 12.2 nM
Cc1nc(N)sc1-c1ccc(N/C(N)=N/C(=O)NCc2ccccc2)cc1 CHEMBL5209021 Kd 12.2 nM
Cc1nc(N)sc1-c1cccc(N/C(N)=N/C(=O)NCc2ccccc2)c1 CHEMBL5173373 Kd 12.2 nM
N/C(=N\C(=O)NCc1ccccc1)NCC1CCc2nc(N)sc2C1 CHEMBL5184846 Kd 12.2 nM
C[C@@H](NC(=O)/N=C(\N)NCCCc1nnc(N)s1)c1ccccc1 CHEMBL5208845 Kd 12.2 nM
C[C@@H](NC(=O)/N=C(\N)NCCCc1ncn[nH]1)c1ccccc1 CHEMBL5201074 Kd 12.2 nM
C[C@@H](NC(=O)/N=C(\N)NCCCn1cc(CN(C)C)nn1)c1ccccc1 CHEMBL5188592 Kd 12.2 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)NCCCc2nnc(N)o2)cc1 CHEMBL5200106 Kd 12.2 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)NCCCc2cnc(N)s2)cc1 CHEMBL5202592 Kd 12.2 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)Nc2ccc(-c3sc(N)nc3C)cc2)cc1 CHEMBL5174342 Kd 12.2 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)Nc2cccc(-c3sc(N)nc3C)c2)cc1 CHEMBL5208327 Kd 12.2 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)NCC2CCc3nc(N)sc3C2)cc1 CHEMBL5208113 Kd 12.2 nM
CC(CCCc1ccccc1)CNC(=O)/N=C(\N)NCCCc1nnc(N)s1 CHEMBL5198795 Kd 12.2 nM
Cc1nc(N)sc1-c1ccc(N/C(N)=N/C(=O)NCC(C)CCCc2ccccc2)cc1 CHEMBL5192993 Kd 12.2 nM
Cc1nc(N)sc1-c1cccc(N/C(N)=N/C(=O)NCC(C)CCCc2ccccc2)c1 CHEMBL5179906 Kd 12.2 nM
CC(CCCc1ccccc1)CNC(=O)/N=C(\N)NCC1CCc2nc(N)sc2C1 CHEMBL5194860 Kd 12.2 nM
Cc1nc(N)sc1-c1ccc(N/C(N)=N/C(=O)NCCCCCCNC(=O)/N=C(\N)Nc2ccc(-c3sc(N)nc3C)cc2)cc1 CHEMBL5172675 Kd 12.2 nM
Cc1nc(N)sc1-c1cccc(N/C(N)=N/C(=O)NCCCCCCNC(=O)/N=C(\N)Nc2cccc(-c3sc(N)nc3C)c2)c1 CHEMBL5174278 Kd 12.2 nM
CCCCCNC(=O)/N=C(/N)NCCCc1nnc(C)s1 CHEMBL5187758 Kd 12.2 nM
C[N+]1=C(/C=C/C=C/C=C2\N(CCCCCC(=O)NCCCCCCNc3c(NCCCOc4cccc(CN5CCCCC5)c4)c(=O)c3=O)c3ccccc3C2(C)C)C(C)(C)c2ccccc21 CHEMBL4647775 pKd 12.88 nM
NCCCCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4642548 pKi 13.49 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1cnc(N)s1 CHEMBL2165645 pEC50 13.8 nM
NCCCCCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4644794 pKi 13.8 nM
Cc1cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc(C)[n+]1CCCCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4637893 pKd 14.45 nM
Nc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4643501 pKi 15.85 nM
CC1(C)C(/C=C/C=C/C=C2\N(CCCCCC(=O)NCCCCCCNc3c(NCCCOc4cccc(CN5CCCCC5)c4)c(=O)c3=O)c3ccccc3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccccc21 CHEMBL4637356 pKd 16.22 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCCCCC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL2165633 pEC50 16.6 nM
Cc1cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc(C)[n+]1CCCCCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4644467 pKi 17.38 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(C)CC1CCCCC1 CHEMBL4857560 pEC50 17.38 nM
Cc1cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc(C)[n+]1CCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4641916 pKi 17.78 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)N[C@H](C)c1ccccc1 CHEMBL4856059 pKi 17.78 nM
C/N=C(/NC#N)NCCSCc1csc(NC(=N)N)n1 CHEMBL269646 Ki 18.0 nM
C[C@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)C1CCCCC1 CHEMBL1096430 pEC50 18.62 nM
Cc1nc(N)sc1CCCNC(=N)NC(=O)C[C@@H](C)C1CCCCC1 CHEMBL1094452 pEC50 20.42 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCc1ccccc1 CHEMBL2165646 pEC50 20.42 nM
CNCc1ccccc1-c1csc([C@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1 CHEMBL4520788 Ki 21.13 nM
CN(C)CCC=C1c2ccccc2CCc2ccccc21 CHEMBL629 AC50 21.3 nM
N/C(=N\C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1cnc(N)s1)NCCCc1cnc(N)s1 CHEMBL2165637 pEC50 21.38 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(C)C1CCCCC1 CHEMBL4846638 pEC50 21.88 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCNC(=O)CCCCCN1/C(=C/C=C/C=C/C2=[N+](C)c3ccccc3C2(C)C)c2ccccc2C1(C)C CHEMBL5094663 pKi 21.88 nM
N/C(=N\C(=O)CCCCCCCCCCCCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 CHEMBL2165643 pEC50 24.55 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCCCCCCCCC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL2165634 pEC50 25.7 nM
CN(C)Cc1ccc(CSCCNc2nonc2N)o1 CHEMBL5273718 Ki 26.0 nM
Cc1nc(N)sc1CCCNC(=N)NC(=O)C[C@H](C)c1ccccc1 CHEMBL1098442 pEC50 28.18 nM
Cc1nc(N)sc1CCCNC(=N)NC(=O)C[C@H](C)C1CCCCC1 CHEMBL1094144 pEC50 28.84 nM
CCCCCCNC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL4853668 pKi 28.84 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccccc1F CHEMBL4864852 pKi 28.84 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCc1ccccc1 CHEMBL4856005 pEC50 28.84 nM
CCC(CNC(=O)/N=C(\N)NCCCc1sc(N)nc1C)c1ccccc1 CHEMBL4848815 pEC50 28.84 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(C)CCc1ccccc1 CHEMBL4865765 pEC50 29.51 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCCCNC(=O)CCCCCNC(=O)COc1ccc(/C=C/C2=[N+]3C(=Cc4ccc(-c5cccs5)n4[B-]3(F)F)C=C2)cc1 CHEMBL5078202 pKi 30.13 nM
N/C(=N\C(=O)CCCNC(=O)c1cc2ccccc2[nH]1)NCCCc1c[nH]cn1 CHEMBL475620 pEC50 30.2 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccc(Br)cc1 CHEMBL4876267 pKi 30.2 nM
N/C(=N\C(=O)CCCCCCC(=O)/N=C(\N)NCCCc1cnc(N)s1)NCCCc1cnc(N)s1 CHEMBL2165636 pEC50 30.9 nM
Cc1ccc(C(C)NC(=O)/N=C(\N)NCCCc2sc(N)nc2C)cc1 CHEMBL4869194 pKi 30.9 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(c1ccccc1)C(C)C CHEMBL4856572 pEC50 30.9 nM
[3H]CC([3H])C(=O)NCCCCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4648685 Kd 31.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccc(F)cc1 CHEMBL4848697 pKi 31.62 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccco1 CHEMBL4846380 pKi 31.62 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(C)c1ccc(C(C)C)cc1 CHEMBL4871482 pEC50 34.67 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(c1ccccc1)C(C)C CHEMBL4858849 pKi 35.48 nM
N/C(=N\C(=O)Cc1c[nH]c2ccccc12)NCCCc1c[nH]cn1 CHEMBL474447 pEC50 36.31 nM
COc1ccc(C(C)NC(=O)/N=C(\N)NCCCc2sc(N)nc2C)cc1 CHEMBL4848026 pKi 37.15 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL4876025 pKi 43.65 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL2165631 pEC50 44.67 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCc1ccccc1 CHEMBL4864067 pEC50 44.67 nM
Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2 CHEMBL85 AC50 45.4 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccc(Cl)cc1 CHEMBL4863347 pKi 46.77 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL2165630 pEC50 47.86 nM
CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 CHEMBL42 AC50 49.8 nM
Cc1nc(N)sc1CCCNC(=N)NC(=O)CC(C)c1ccccc1 CHEMBL1098110 pEC50 50.12 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)N[C@@H](C)c1ccccc1 CHEMBL4867962 pKi 51.29 nM
CN(C)CCC=C1c2ccccc2COc2ccccc21 CHEMBL1628227 AC50 52.0 nM
CC(CN1c2ccccc2Sc2ccccc21)N(C)C CHEMBL643 AC50 53.6 nM
Cc1nc(N)sc1CCCNC(=N)NC(=O)C[C@@H](C)c1ccccc1 CHEMBL1098441 pEC50 53.7 nM
CN1CCN2c3ccccc3Cc3ccccc3C2C1 CHEMBL6437 AC50 53.8 nM
N/C(=N\C(=O)CCCCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 CHEMBL2165641 pEC50 56.23 nM
CC1(C)C(/C=C/C=C/C=C2\c3ccccc3C(C)(C)N2CCCCCC(=O)NCCCCCCCCNC(=O)/N=C(\N)NCCCc2c[nH]cn2)=[N+](CCCCS(=O)(=O)[O-])c2ccccc21 CHEMBL5075713 pKd 56.23 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL2165647 pEC50 57.54 nM
CC[C@@H](CO)NC(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL1201356 AC50 58.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(C)CCCc1ccccc1 CHEMBL4846201 pKi 60.26 nM
Cc1ccc(CC(C)CNC(=O)/N=C(\N)NCCCc2sc(N)nc2C)cc1 CHEMBL4853107 pEC50 60.26 nM
CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1 CHEMBL1790041 Kd 63.0 nM
N=C(NCCCc1c[nH]cn1)NC(=O)CCc1ccccc1 CHEMBL470790 pEC50 63.1 nM
CC(CC(=O)/N=C(\N)NCCCc1c[nH]cn1)c1ccccc1 CHEMBL483406 pEC50 63.1 nM
CCC(NC(=O)/N=C(\N)NCCCc1sc(N)nc1C)c1ccccc1 CHEMBL4870510 pKi 63.1 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1cccs1 CHEMBL4861704 pKi 63.1 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCC[n+]1c(C)cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc1C CHEMBL5092267 pKi 63.1 nM
CC1(C)C(/C=C/C=C/C=C2\c3ccccc3C(C)(C)N2CCCCCC(=O)NCCCCCCCCNC(=O)/N=C(\N)NCCCc2nnc(N)s2)=[N+](CCCCS(=O)(=O)[O-])c2ccccc21 CHEMBL5093461 pEC50 64.57 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCCC[n+]1c(C)cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc1C CHEMBL5085542 pEC50 69.18 nM
CN(C)CCCN1c2ccccc2CCc2ccccc21 CHEMBL11 AC50 69.7 nM
CN/C(=N\CCSCc1nc[nH]c1C)NC#N CHEMBL30 Ki 70.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCCCNC(=O)CCCCCN1/C(=C/C=C/C=C/C2=[N+](CCCCS(=O)(=O)[O-])c3ccccc3C2(C)C)c2ccccc2C1(C)C CHEMBL5083588 pKd 70.79 nM
CC1CCCc2c(-c3ccc(F)cc3)nc(N)nc21 CHEMBL4456972 pEC50 75.86 nM
CC1CCCc2c(-c3ccc(Cl)cc3)nc(N)nc21 CHEMBL4576986 pEC50 77.62 nM
N=C(NCCCc1c[nH]cn1)NC(=O)CC(c1ccccc1)c1ccccc1 CHEMBL471413 EC50 78.0 nM
C[C@@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)c1ccccc1 CHEMBL1096429 pEC50 79.43 nM
CN1CCC2C(C1)c1cccc3c1N2c1ccccc1CS3 CHEMBL3217984 pKi 79.43 nM
CN1CCc2c(c3cccc4c3n2-c2ccccc2CC4)C1 CHEMBL3104091 Ki 81.0 nM
N/C(=N\C(=O)CCc1c[nH]c2ccccc12)NCCCc1c[nH]cn1 CHEMBL514641 pEC50 81.28 nM
N/C(=N\C(=O)CCNC(=O)c1cc2ccccc2[nH]1)NCCCc1c[nH]cn1 CHEMBL515428 pEC50 83.18 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCC(c1ccccc1)c1ccccc1 CHEMBL4866734 pKi 87.1 nM
CCCCCCCCNC(C)C(O)c1ccc(SC(C)C)cc1 CHEMBL404849 Ki 88.5 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCCCCC[n+]1c(C)cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc1C CHEMBL5090859 pEC50 89.13 nM
NCC[C@H]1C[C@H]1c1c[nH]cn1 CHEMBL418470 EC50 93.0 nM
N/C(=N\C(=O)CCCCCCCCCCCCCCC(=O)/N=C(\N)NCCCc1cnc(N)s1)NCCCc1cnc(N)s1 CHEMBL2165638 pEC50 93.33 nM
CC1CCCc2c(-c3ccccc3)nc(N)nc21 CHEMBL4563363 pEC50 95.5 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCCCCCNC(=O)CCCCCN1/C(=C/C=C/C=C/C2=[N+](CCCCS(=O)(=O)[O-])c3ccccc3C2(C)C)c2ccccc2C1(C)C CHEMBL5088914 pKi 95.5 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC[C@H](C)c1ccccc1 CHEMBL4852212 pKi 100.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC[C@@H](C)c1ccccc1 CHEMBL4869389 pKi 102.33 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21 CHEMBL19215 Activity 104.0 nM
CCCNC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL4874758 pKi 104.71 nM
CC(CC(=O)NC(=N)NCCCc1c[nH]cn1)c1cccs1 CHEMBL502339 EC50 109.0 nM
CC(C)C(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL471724 pEC50 109.65 nM
CN(C)CCCN1c2ccccc2Sc2ccccc21 CHEMBL564 AC50 110.8 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=S)N[C@H](C)c1ccccc1 CHEMBL4853772 pKi 114.82 nM
O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL54 AC50 116.8 nM
N=C(NCCCc1c[nH]cn1)NC(=O)CC(c1ccccc1)c1nccs1 CHEMBL472441 EC50 120.0 nM
C[C@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)c1ccccc1 CHEMBL1096428 pEC50 120.23 nM
C[N+]1=C(/C=C/C=C/C=C2\N(CCCCCC(=O)NCCCCNc3c(NCCCOc4cccc(CN5CCCCC5)c4)c(=O)c3=O)c3ccccc3C2(C)C)C(C)(C)c2ccccc21 CHEMBL4645867 pKd 120.23 nM
CCOCCn1cc(C2CCN(CCOc3cccc(C(=O)O)c3)CC2)c2ccccc21 CHEMBL223024 IC50 123.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccc(OC(F)(F)F)cc1 CHEMBL4863523 pKi 125.89 nM
Cc1cc(OCCCN2CCc3nc[nH]c3C2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 CHEMBL1086105 EC50 131.0 nM
CNCc1ccccc1-c1csc([C@@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1 CHEMBL4535474 pKi 139.64 nM
CN1CCN(C2=Nc3ccccc3Oc3ccc(Cl)cc32)CC1 CHEMBL831 AC50 139.9 nM
CCCC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL465170 pEC50 141.25 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 142.0 nM
CN1CCN(c2ccnc(NCCc3ccccc3)n2)CC1 CHEMBL4748908 pKi 144.54 nM
CN1CCN(CC/C=C2/c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1 CHEMBL1201 AC50 144.9 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC1CCCCC1 CHEMBL4876743 pEC50 147.91 nM
CCCCCCNC(=O)/N=C(\N)NC1CCc2nc(N)sc2C1 CHEMBL4876799 pEC50 147.91 nM
N/C(=N\C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1ncn[nH]1)NCCCc1ncn[nH]1 CHEMBL2165629 pEC50 151.36 nM
CC1(C)C(/C=C/C=C/C=C2/N(CCCCCC(=O)NCC/N=C(\NC#N)NCCCOc3cccc(CN4CCCCC4)c3)c3ccccc3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccccc21 CHEMBL213357 EC50 160.0 nM
CC1(C)C(/C=C/C=C/C=C2\N(CCCCCC(=O)NCCCCNc3c(NCCCOc4cccc(CN5CCCCC5)c4)c(=O)c3=O)c3ccccc3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccccc21 CHEMBL4645213 pKd 169.82 nM
CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21 CHEMBL71 AC50 171.2 nM
Cc1ccc(Sc2ccccc2N2CCNCC2)c(C)c1 CHEMBL2204360 Ki 180.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCNC(=O)CCCCCN1/C(=C/C=C/C=C/C2=[N+](CCCCS(N)(=O)=O)c3ccccc3C2(C)C)c2cc(S(=O)(=O)[O-])ccc2C1(C)C CHEMBL5076746 pKi 181.97 nM
OCCOCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL896 AC50 188.4 nM
Cc1nc(N)sc1CCN CHEMBL293762 pEC50 190.55 nM
CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 CHEMBL516 Ki 195.0 nM
N/C(=N\C(=O)CCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 CHEMBL2165640 pEC50 213.8 nM
N/C(=N\C(=O)NCc1ccccc1)NC1CCc2nc(N)sc2C1 CHEMBL4878215 pEC50 213.8 nM
Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C)C1 CHEMBL589390 Ki 215.25 nM
CCCN(CC[C@]1(O)C[C@H](NC(=O)c2ccc3ccccc3c2)C1)[C@H]1CCc2nc(N)sc2C1 CHEMBL2203406 Ki 224.0 nM
CCOCCn1cc(C2CCN(CCOc3ccc(C)cc3C(=O)O)CC2)c2ccccc21 CHEMBL221462 IC50 225.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(c1ccccc1)C(F)(F)F CHEMBL4850448 pKi 229.09 nM
CC(CC(=O)/N=C(\N)NCCCc1cn[nH]c1)c1ccccc1 CHEMBL3220633 pEC50 239.88 nM
COc1cccc(-c2nc(N)nc3c2CCCC3C)c1 CHEMBL4452406 pEC50 245.47 nM
CC(=O)OCC(=O)NCCCOc1cccc(CN2CCCCC2)c1 CHEMBL46102 pA2 251.19 nM
CN1C(=O)[C@H](NC(=O)Nc2ccc(CC(=O)NCCC(=O)NCCCOc3cccc(CN4CCCCC4)c3)cc2)N=C(c2ccccc2)c2ccccc21 CHEMBL196143 pA2 251.19 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCNC(=O)CCCCCN1/C(=C/C=C/C=C/C2=[N+](CCCCS(=O)(=O)[O-])c3ccccc3C2(C)C)c2ccccc2C1(C)C CHEMBL5087637 pKi 251.19 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCN(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL4291048 Ki 252.0 nM
CN(C)CCOC(c1ccccc1)c1ccccc1 CHEMBL657 AC50 252.2 nM
CN1C[C@H](C(=O)N[C@]2(C)O[C@@]3(O)[C@@H]4CCCN4C(=O)[C@H](Cc4ccccc4)N3C2=O)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL1732 AC50 256.6 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL726 AC50 259.7 nM
CCOCCn1cc(C2CCN(CCOc3ccccc3C(=O)O)CC2)c2ccc(F)cc21 CHEMBL221413 IC50 260.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NCCCCCCCCNC(=O)CCCCCN1/C(=C/C=C/C=C/C2=[N+](CCCCS(=O)(=O)O)c3ccccc3C2(C)C)c2cc(S(=O)(=O)[O-])ccc2C1(C)C CHEMBL5077939 pKi 263.03 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 CHEMBL1644980 Ki 278.0 nM
Clc1ccc2c(c1)C(N1CCNCC1)=Nc1ccccc1O2 CHEMBL1113 AC50 282.7 nM
CN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)C3)CC1 CHEMBL4163428 Ki 285.0 nM
N/C(=N\C(=O)c1cc2ccccc2[nH]1)NCCCc1c[nH]cn1 CHEMBL474448 pEC50 288.4 nM
O=C(c1ccc(OCCCN2CC[C@H](NS(=O)(=O)c3ccc(Cl)cc3)C2)cc1)C1CC1 CHEMBL104344 Ki 290.0 nM
O=C(c1ccc(OCCCN2CC[C@H](NS(=O)(=O)c3ccc(Br)cc3)C2)cc1)C1CC1 CHEMBL321709 Ki 290.0 nM
Cn1c(=O)cnn(CCCCN2CCN(c3cccc4ccc(O[11CH3])cc34)CC2)c1=O CHEMBL199824 Ki 302.0 nM
NCCCCNc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O CHEMBL4632998 pKi 302.0 nM
CC1CCCc2c(-c3cccc(Br)c3)nc(N)nc21 CHEMBL4580450 pEC50 316.23 nM
CCc1ccc(S(=O)(=O)N[C@H]2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)cc1 CHEMBL102925 Ki 330.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=S)N[C@@H](C)c1ccccc1 CHEMBL4854278 pKi 338.84 nM
CN(CCC(=O)/N=C(\N)NCCCc1c[nH]cn1)C(=O)c1cc2ccccc2[nH]1 CHEMBL474617 pEC50 346.74 nM
CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21 CHEMBL549 AC50 349.6 nM
CC1CCCc2c1nc(N)nc2C1CCCCC1 CHEMBL4585616 EC50 360.0 nM
CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1 CHEMBL1626 Ki 364.0 nM
NCCCCCCn1cc(CCCCN2CCC(c3ccc(-c4cc(C(=O)O)cc5cc(-c6ccc(C(F)(F)F)cc6)ccc45)cc3)CC2)nn1 CHEMBL4216870 Ki 365.0 nM
N#Cc1ccc(CCOC(=O)NC2CCN(CCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL116463 IC50 368.0 nM
CCC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL475621 pEC50 371.54 nM
Cc1ccc(S(=O)(=O)N[C@H]2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)cc1 CHEMBL107293 Ki 380.0 nM
NC(=O)/N=C(/NCCCCc1ccccc1)NCCCc1c[nH]cn1 CHEMBL1078746 pEC50 380.19 nM
Clc1cccc(Cl)c1NC1=NCCN1 CHEMBL134 AC50 390.0 nM
CNCCCC12CCC(c3ccccc31)c1ccccc12 CHEMBL21731 Ki 393.0 nM
COc1ccc(CCN2C3C4C5CC6C7C5C3C7C2(O)C64)cc1 CHEMBL2205812 Ki 400.0 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCCCc2ccc(F)cc2)CC1 CHEMBL4282702 Ki 401.0 nM
N/C(=N\C(=O)CC(c1ccccc1)c1ccccc1)NCCCc1ncn[nH]1 CHEMBL3220636 pEC50 407.38 nM
OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1 CHEMBL716 AC50 410.2 nM
COc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 CHEMBL296419 AC50 411.5 nM
CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1 CHEMBL505 AC50 412.3 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=S)NC[C@@H](C)c1ccccc1 CHEMBL4845733 pKi 426.58 nM
Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1 CHEMBL715 AC50 430.1 nM
NC(=O)/N=C(/NCCCc1ccccc1)NCCCc1c[nH]cn1 CHEMBL1078359 pEC50 436.52 nM
Cc1cccc(Cl)c1-c1nc(CN2CCC(C(=O)NCCCN3C[C@H](C)C[C@H](C)C3)CC2)c(C)o1 CHEMBL4066784 Ki 443.0 nM
CC1(C)C(/C=C/C=C/C=C2\N(CCCCCC(=O)NCCCCCCNc3c(NCCCOc4cccc(CN5CCCCC5)c4)c(=O)c3=O)c3cc(S(=O)(=O)O)ccc3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccccc21 CHEMBL4641747 pKd 446.68 nM
COc1ccccc1N1CCN(Cc2cc(CN3CCN(c4ccc(Cl)cc4)CC3)c3cccccc2-3)CC1 CHEMBL2207642 Ki 460.0 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL422 AC50 470.2 nM
O=C(c1ccc(OCCCN2CC[C@H](NS(=O)(=O)c3ccc(F)cc3)C2)cc1)C1CC1 CHEMBL104808 Ki 500.0 nM
CCOCCn1cc(C2CCN(CCOc3c(Br)cc(Br)cc3C(=O)O)CC2)c2ccccc21 CHEMBL221414 IC50 500.0 nM
CCOCCn1cc(C2CCN(CCOc3ccccc3C(=O)O)CC2)c2cc(F)ccc21 CHEMBL374585 IC50 500.0 nM
O=C(O)c1ccccc1OCCN1CCC(c2cn(Cc3cccs3)c3ccccc23)CC1 CHEMBL222881 IC50 500.0 nM
Cc1[nH]cnc1CSCCNC(=N)NCCCc1c[nH]cn1 CHEMBL12608 pKi 501.19 nM
CCOC(=O)CCN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CC1 CHEMBL4169689 Ki 507.0 nM
Clc1ccc(C#Cc2nc(NCCc3ccccc3)c3nc[nH]c3n2)s1 CHEMBL4546937 Ki 520.0 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)Nc1ccccc1 CHEMBL4858567 pEC50 524.81 nM
CCOC(=O)C1=C(C)NC(CSCCCCCNC(=N)NCCCc2ccc[nH]2)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1 CHEMBL5207008 pEC50 524.81 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL4287623 Ki 526.0 nM
COc1ccccc1N1CCN(Cc2cc(CN3CCN(c4ccccc4OC)CC3)c3cccccc2-3)CC1 CHEMBL2207641 Ki 530.0 nM
O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc21 CHEMBL481153 Ki 540.0 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1644978 Ki 546.0 nM
Cc1cccc(C)c1N1C(=O)[C@H](CC2CNc3ccccc32)NC2(CCN(C)CC2)C1=O CHEMBL4562437 Ki 546.0 nM
Cc1[nH]cnc1CSCCNc1ccnc(NCC(C)(C)C)n1 CHEMBL4466349 pKi 562.34 nM
CN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 CHEMBL543113 Ki 593.75 nM
COc1ccccc1N1CCC2(CCN(CCCSc3nnc(-c4ccccc4)n3C)CC2)CC1 CHEMBL4084262 Ki 596.0 nM
O=C1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1 CHEMBL708 AC50 596.2 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=S)NC(c1ccccc1)c1ccccc1 CHEMBL4856602 pKi 602.56 nM
NC(=O)C(c1ccccc1)(c1ccccc1)[C@@H]1CCN(CCc2ccc3c(c2)CCO3)C1 CHEMBL1346 AC50 628.4 nM
O=C(O)c1cccc(CN2CCC(c3cn(Cc4ccco4)c4ccccc34)CC2)c1 CHEMBL222985 IC50 630.0 nM
O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1423 AC50 640.2 nM
COc1cc2c3c(c1OC)-c1cc4c(cc1CC3N(C)CC2)OCO4 CHEMBL467094 Ki 672.0 nM
CCOCCn1cc(C2CCN(CCOc3ccc(C(=O)O)cc3)CC2)c2ccccc21 CHEMBL222853 IC50 691.0 nM
CCCCCCNC(=O)/N=C(\N)Nc1cccc(-c2csc(N)n2)c1 CHEMBL4872375 pKi 691.83 nM
N[C@H]1C[C@@H]1c1c[nH]cn1 CHEMBL13795 EC50 696.0 nM
CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 CHEMBL998 AC50 696.4 nM
O=C(c1ccc(OCCCN2CC[C@H](NS(=O)(=O)c3cccc(Cl)c3)C2)cc1)C1CC1 CHEMBL321320 Ki 700.0 nM
CN(C)CCCn1c2c(c3ccccc31)CCCCCC2 CHEMBL126224 AC50 704.7 nM
N#Cc1ccccc1S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(C(=O)C3CC3)cc2)C1 CHEMBL420108 Ki 710.0 nM
CC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL443896 pEC50 724.44 nM
CC(C)(C)c1ccc(S(=O)(=O)N[C@H]2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)cc1 CHEMBL105071 Ki 730.0 nM
CC(CC(=O)/N=C(\N)NCCCc1ncn[nH]1)c1ccccc1 CHEMBL3220635 pEC50 741.31 nM
COc1cccc(CCN2C3C4C5CC6C7C5C3C7C2(O)C64)c1OC CHEMBL2205813 Ki 743.0 nM
CCN(CC)CCCC(C)Nc1cnc(C(=O)Nc2cc(F)cc3cccnc23)cn1 CHEMBL5431371 Ki 750.0 nM
CCOc1ccc(CCNC(=O)N2CCN(CCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL113956 IC50 757.0 nM
CCOCCn1cc(C2CCN(CCOc3cc(OC)ccc3C(=O)O)CC2)c2ccccc21 CHEMBL181278 IC50 779.0 nM
C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(-c5nc6cc[nH]c(=O)c6cc5-c5ccccc5)cc4)CC3)c2c1 CHEMBL4795065 pKi 812.83 nM
CC1=NC2(CCN(C)CC2)C(=O)N(c2c(C)cccc2C)C1=O CHEMBL4514672 Ki 823.0 nM
COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(C)cc2)CC1 CHEMBL490632 Ki 827.0 nM
CC(C)(C)OC(=O)NCCCCCCn1cc(CCCCN2CCC(c3ccc(-c4cc(C(=O)O)cc5cc(-c6ccc(C(F)(F)F)cc6)ccc45)cc3)CC2)nn1 CHEMBL4217398 Ki 829.0 nM
CC(CC(=O)/N=C(\N)NCCCc1ccccn1)c1ccccc1 CHEMBL3220665 pEC50 831.76 nM
CCOCCn1cc(C2CCN(CCOc3cccc(F)c3C(=O)O)CC2)c2ccccc21 CHEMBL376025 IC50 850.0 nM
CC(C)(C)c1ccc(-c2nc3c(N4CCN(Cc5ccc6nccnc6c5)CC4)cccc3[nH]2)cc1 CHEMBL474991 Ki 850.0 nM
Cc1cc(N(C)CCN(C)C)nc2ccc(NC(=O)/C=C/c3ccc(OC(F)(F)F)cc3)cc12 CHEMBL189118 IC50 860.0 nM
O=C(O)c1ccccc1OCCN1CCC(c2cn(Cc3ccco3)c3cc(F)ccc23)CC1 CHEMBL223837 IC50 870.0 nM
COc1ccccc1N1CCN(CCCSc2nnc(-c3ccccc3)n2C)CC1 CHEMBL4083252 Ki 871.0 nM
O=C(O)c1ccccc1OCCN1CCC(c2cn(Cc3ccoc3)c3cc(F)ccc23)CC1 CHEMBL374675 IC50 880.0 nM
Cc1ccc(-c2nc(N)nc3c2CCCC3C)cc1 CHEMBL4467878 EC50 880.0 nM
N#Cc1cccc(S(=O)(=O)N[C@H]2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)c1 CHEMBL101748 Ki 900.0 nM
NCCc1cc[nH]n1 CHEMBL1201323 AC50 910.0 nM
C[C@@H]1CCCN1CCc1cc2cc(C(=O)c3ccc([N+](=O)[O-])cc3)ccc2o1 CHEMBL2031737 Ki 923.0 nM
Clc1ccc2nsnc2c1NC1=NCCN1 CHEMBL1079 AC50 930.0 nM
CN1CCc2c(c3cccc4c3n2CCc2ccccc2-4)C1 CHEMBL3104093 pKi 933.25 nM
CSc1ccc2c(c1)N(CCC1CCCCN1C)c1ccccc1S2 CHEMBL479 Ki 934.0 nM
COc1cccc(CCN2C3C4C5CC6C7C5C3C7C2(O)C64)c1 CHEMBL2205811 Ki 948.0 nM
CCOCCn1cc(C2CCN(CCOc3ccc(C(C)=O)cc3C(=O)O)CC2)c2ccccc21 CHEMBL374755 IC50 950.0 nM
CCCN1C[C@H](CSC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL531 AC50 950.0 nM
N/C(=N\C(=O)CNC(=O)c1cc2ccccc2[nH]1)NCCCc1c[nH]cn1 CHEMBL474449 pEC50 954.99 nM
COc1cc(-c2cn([C@H]3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1 CHEMBL3609749 Ki 975.0 nM
C=C(C)CN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CC1 CHEMBL4173095 Ki 985.0 nM
O=C(c1ccc(OCCCN2CC[C@H](NS(=O)(=O)c3ccccc3Cl)C2)cc1)C1CC1 CHEMBL102384 Ki 1000.0 nM
COc1ccc(S(=O)(=O)N[C@H]2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)cc1 CHEMBL107162 Ki 1000.0 nM
COc1ccc(CN2CCCN(Cc3ccccc3)[C@@H](C)C2)cc1 CHEMBL4086541 IC50 1000.0 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL47050 Ki 1000.0 nM