CN[C@@H]1CCN(c2ccnc(NC3CC4CCC3C4)c2)C1 CHEMBL3393534 pA2 0.00631 nM
CNC1CN(c2cc(NCC(C)(C)C)nc(N)n2)C1 CHEMBL1915536 Ki 0.034 nM
CN[C@@H]1CCN(c2cc(N)nc(NCC(C)(C)C)c2)C1 CHEMBL1770975 Ki 0.04 nM
CN[C@@H]1CCN(c2ccnc(NC3CC4CCC3C4)n2)C1 CHEMBL3393547 pA2 0.07943 nM
CN1CCN(c2nc(N)nc3c2oc2ccc(Cl)cc23)CC1 CHEMBL1914541 Ki 0.1 nM
Nc1nc(C2CCCC2)cc(N2C[C@H]3CCN[C@H]3C2)n1 CHEMBL3236561 pA2 0.1 nM
CC(C)(C)CNc1nccc(N2CCc3nc[nH]c3C2)n1 CHEMBL4454158 pEC50 0.123 nM
CN1CCN(c2cc(C3CCCC3)nc(N)n2)CC1 CHEMBL3236552 pA2 0.1259 nM
CN[C@@H]1CCN(c2cc(N)nc(NCC(C)C)c2)C1 CHEMBL1770971 Ki 0.2 nM
Cc1cc(OCCCNCCc2c[nH]cn2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 CHEMBL1083162 Ki 0.21 nM
CN[C@@H]1CCN(c2cc(C3CCCC3)nc(N)n2)C1 CHEMBL3236554 pA2 0.2512 nM
CN1CCN(c2cc(N)nc(NCC(C)(C)C)c2)CC1 CHEMBL1770968 Ki 0.3 nM
CN1CCN(c2nc(N)nc3c2sc2ccc(Cl)cc23)CC1 CHEMBL1914462 Ki 0.3 nM
Nc1nc(C2CCCC2)cc(N2CCNCC2)n1 CHEMBL3236553 pA2 0.3162 nM
CN[C@@H]1CCN(c2cc(NC3CCCC3)nc(N)n2)C1 CHEMBL1770980 pA2 0.3981 nM
CN[C@@H]1CCN(c2cc(C3CCC3)nc(N)n2)C1 CHEMBL3236575 pA2 0.3981 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1 CHEMBL1091874 Ki 0.4 nM
CN[C@@H]1CCN(c2cc(NCC(C)C)nc(N)n2)C1 CHEMBL1770979 pA2 0.5012 nM
CN[C@@H]1CCN(c2ccnc(NCC(C)(C)C)n2)C1 CHEMBL4443126 pEC50 0.6026 nM
Nc1nc(C2CCCC2)cc(N2CC[C@@H](N)C2)n1 CHEMBL3236556 pA2 0.631 nM
CN[C@@H]1CCN(c2ccnc(NCC(C)C)c2)C1 CHEMBL3393526 pA2 0.631 nM
CN[C@@H]1CCN(c2cc(NCC3CC3)nc(N)n2)C1 CHEMBL1915540 IC50 0.65 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2ccc(Br)cc23)C1 CHEMBL1914781 Ki 0.7 nM
CN1CCN(c2nc(N)nc3c2oc2ccc(C(F)(F)F)cc23)CC1 CHEMBL1914755 Ki 0.8 nM
CN[C@@H]1CCN(c2cc(N)nc(NC3CCCC3)c2)C1 CHEMBL1770973 Ki 0.9 nM
CNC1CCN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1 CHEMBL1914750 Ki 0.9 nM
Cc1cc(C)c2nc(-c3ccc(OCCCN4CCCN(C)CC4)cc3Cl)[nH]c2c1 CHEMBL373579 Ki 1.0 nM
c1nc(CCCn2cc(CC3CCCCC3)nn2)c[nH]1 CHEMBL1688946 pEC50 1.0 nM
CN1CCN(c2cc(NC3CCCC3)nc(N)n2)CC1 CHEMBL1771001 Ki 1.0 nM
CN[C@@H]1CCN(c2cc(N)nc(NCC(C)C)n2)C1 CHEMBL1770992 Ki 1.0 nM
CN1CCN(c2nc(N)nc3c2sc2ccc(Br)cc23)CC1 CHEMBL1914760 Ki 1.0 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2ccc(C(F)(F)F)cc23)C1 CHEMBL1914783 Ki 1.0 nM
N=C(NCc1ccc(Cl)cc1)SCCCc1c[nH]cn1 CHEMBL14690 pKi 1.0 nM
CN[C@@H]1CCN(c2ccnc(NC3CCCC3)c2)C1 CHEMBL3393532 pA2 1.0 nM
CN[C@H]1CCN(c2ccnc(NC3CC4CCC3C4)c2)C1 CHEMBL3393535 pA2 1.0 nM
CN[C@H]1CCN(c2nc(N)nc3c2oc2ccc(C(C)(F)F)cc23)C1 CHEMBL3819260 pKi 1.0 nM
NCCc1c[nH]cn1 CHEMBL90 pKi 1.0 nM
CC(C)(C)c1ccc(SCCc2c[nH]cn2)cc1 CHEMBL1098230 Ki 1.1 nM
Nc1nc(N2CCCNCC2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914540 Ki 1.1 nM
Nc1nc(N2CCNCC2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914542 Ki 1.1 nM
c1ccc(C(OCCCc2c[nH]cn2)c2nc3ccccc3s2)cc1 CHEMBL3911109 Kb 1.1 nM
CN1CCN(c2cc(NCc3c(Cl)cccc3Cl)nc(N)n2)CC1 CHEMBL595180 pEC50 1.122 nM
CC(C)(C)CNc1nccc(N2CCc3nc[nH]c3C2)n1 CHEMBL4597218 pKi 1.175 nM
CC(C)CNc1cc(N2CCN(C)CC2)nc(N)n1 CHEMBL1771000 pA2 1.259 nM
CNC1CN(c2cc(NCCC(C)(C)C)nc(N)n2)C1 CHEMBL1915537 Ki 1.5 nM
CCCCc1cc(N2CC[C@@H](NC)C2)nc(N)n1 CHEMBL3236571 Ki 1.5 nM
CNC1CN(c2nc(N)nc3c2CCCC32CCCC2)C1 CHEMBL1079516 pKi 1.514 nM
N=C(NCc1ccc(Cl)c(Cl)c1)SCCCc1c[nH]cn1 CHEMBL1202332 pKi 1.585 nM
N=C(NCc1ccc(Cl)c(Cl)c1)SCCCc1c[nH]cn1 CHEMBL553423 pKi 1.585 nM
CN[C@@H]1CCN(c2cc(N)nc(NC(C)C)c2)C1 CHEMBL1770969 pA2 1.585 nM
N=C(N)SCCc1c[nH]cn1 CHEMBL19439 Ki 1.6 nM
Cc1[nH]cnc1CCCOC(c1ccccc1)c1nc2ccccc2s1 CHEMBL3973114 Kb 1.6 nM
CN[C@@H]1CCN(c2cc(C34CC5CC(CC(C5)C3)C4)nc(N)n2)C1 CHEMBL3236579 Ki 1.7 nM
Cc1cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc(C)[n+]1CCCCc1c[nH]cn1 CHEMBL4635634 pIC50 1.738 nM
Nc1nc(C2CCCC2)cc(N2C[C@H]3CCCN[C@H]3C2)n1 CHEMBL3236560 Ki 1.8 nM
CN(C)[C@@H]1CCN(c2ccnc(NCC(C)(C)C)n2)C1 CHEMBL4439142 pEC50 1.905 nM
CN[C@@H]1CCN(c2nc(N)nc3c2CCCC32CCCC2)C1 CHEMBL1089390 pKi 1.995 nM
CN1CCN(c2cc(N3CCCC3)nc(N)n2)CC1 CHEMBL505061 pA2 1.995 nM
CN1CCN(c2cc(-c3ccc(Cl)cc3)nc(N)n2)CC1 CHEMBL493720 pKi 1.995 nM
CC(C)CNc1cc(N2CCN(C)CC2)cc(N)n1 CHEMBL1770964 Ki 2.0 nM
CN[C@H]1CCN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1 CHEMBL1091875 Ki 2.0 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2ccc(F)cc23)C1 CHEMBL1914782 Ki 2.0 nM
Nc1cc(N2CCNCC2)cc(NC2CCCC2)n1 CHEMBL3354820 Ki 2.0 nM
CN[C@@H]1CCN(c2ccnc(NC3CCCC3)n2)C1 CHEMBL3393544 Ki 2.0 nM
CN[C@@H]1CCN(c2ccnc(NCC(C)C)n2)C1 CHEMBL3393539 Ki 2.0 nM
CN[C@@H]1CCN(c2nc(N)nc3c2sc2ccc(Br)cc23)C1 CHEMBL1914788 Ki 2.1 nM
CN[C@@H]1CCN(c2cc(C3CCCCC3)nc(N)n2)C1 CHEMBL3236576 Ki 2.3 nM
Nc1nc(N2CC[C@@H](N)C2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914543 Ki 2.4 nM
Nc1nc(C2CCCC2)cc(N2CCC3(CCCN3)C2)n1 CHEMBL3236564 pA2 2.512 nM
CN[C@@H]1CCN(c2cc(C(C)(C)C)nc(N)n2)C1 CHEMBL3236577 pA2 2.512 nM
CCCC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL465170 pEC50 2.57 nM
C[C@@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)c1ccccc1 CHEMBL1096429 pEC50 2.63 nM
O=[N+]([O-])c1cccc(C(OCCCc2c[nH]cn2)c2ccccc2)c1 CHEMBL4102970 Ki 2.7 nM
CN1CCN(C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1 CHEMBL129198 Kb 2.8 nM
Cc1c(Cl)sc2cc(C(=O)N3CCN(C)CC3)[nH]c12 CHEMBL199062 Ki 3.0 nM
CC(C)Nc1cc(N2CCN(C)CC2)nc(N)n1 CHEMBL1770998 Ki 3.0 nM
CN[C@@H]1CCN(c2cc(NC(C)C)nc(N)n2)C1 CHEMBL1770977 Ki 3.0 nM
CN1CCN(c2cc(N)nc(NC3CCCC3)c2)CC1 CHEMBL1770966 Ki 3.0 nM
CN1CCN(c2nc(N)nc3cc(-c4ccsc4)ccc23)CC1 CHEMBL1935572 Ki 3.0 nM
CCCCNc1nccc(N2CC[C@@H](NC)C2)n1 CHEMBL3393542 Ki 3.0 nM
Ic1ccc(C(OCCCc2c[nH]cn2)c2ccccc2)cc1 CHEMBL4065099 Ki 3.0 nM
CCC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL475621 pEC50 3.02 nM
CC(C)CCc1cc(N2CCN(C)CC2)nc(N)n1 CHEMBL2375772 pKi 3.162 nM
CN[C@@H]1CCN(c2ccnc(NC(C)C)c2)C1 CHEMBL3354816 pA2 3.162 nM
CCCNC1CN(c2ccnc(N)n2)C1 CHEMBL4441731 pEC50 3.162 nM
Cc1cc(OCCCN2CCc3nc[nH]c3C2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 CHEMBL1086105 Ki 3.3 nM
Cc1cc(OCCCNCc2cccnc2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 CHEMBL1084355 EC50 3.3 nM
CNC1CN(c2nc(N)nc3cc(C4CCCC4)ccc23)C1 CHEMBL2376790 pKi 3.388 nM
CN[C@H]1CCN(c2nc(N)nc3c2oc2ccccc23)C1 CHEMBL3819470 pKi 3.388 nM
NCC1CN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1 CHEMBL1914547 Ki 3.4 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2ccccc23)C1 CHEMBL1914776 Ki 3.4 nM
CN[C@@H]1CCN(c2nc(N)nc3c2CCCc2ccccc2-3)C1 CHEMBL521996 pKi 3.467 nM
CC(C)(C)CNc1nccc(N2CC[C@@H](N)C2)n1 CHEMBL4455324 pEC50 3.548 nM
Nc1nc(N2CC3CCNC3C2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914745 Ki 3.6 nM
c1ccc(C(OCCc2c[nH]cn2)c2nc3ccccc3s2)cc1 CHEMBL3893115 Kb 3.7 nM
CC(C)C(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL471724 pEC50 3.715 nM
S=C(NC1CCCCC1)N1CCC(c2cnc[nH]2)CC1 CHEMBL260374 pKi 3.981 nM
CN1CCN(c2nc(NCCS(=O)(=O)Nc3ccccc3)c3cc(Cl)ccc3n2)CC1 CHEMBL592379 Ki 4.0 nM
CN1CCN(c2nc(N)nc3cc(-c4ccoc4)ccc23)CC1 CHEMBL1935571 Ki 4.0 nM
Cc1nc(NCCCC2CCN(C)CC2)ncc1-c1nc2c(C)cc(F)cc2[nH]1 CHEMBL3917992 Ki 4.0 nM
Brc1ccc(C(OCCCc2c[nH]cn2)c2ccc3ccccc3c2)cc1 CHEMBL4098585 Ki 4.0 nM
CNS(=O)(=O)CCNc1nc(N2CCN(C)CC2)nc2ccc(Cl)cc12 CHEMBL591011 pKi 4.266 nM
CN1CCN(c2nc(NCCS(N)(=O)=O)c3cc(Cl)ccc3n2)CC1 CHEMBL591969 pKi 4.467 nM
C[C@@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)C1CCCCC1 CHEMBL1096431 pEC50 4.571 nM
Cc1c(F)ccc2[nH]c(C(=N)N3C[C@H]4CN(C)C[C@H]4C3)nc12 CHEMBL1938975 Ki 4.6 nM
CN1C[C@@H]2CN(C(=N)c3nc4cc(F)ccc4[nH]3)C[C@@H]2C1 CHEMBL1938977 Ki 4.6 nM
Nc1nc2c(c(N3CC[C@@H](N)C3)n1)CCCc1ccccc1-2 CHEMBL502347 pKi 4.677 nM
CN1CCN(c2ncnc3c2oc2ccc(Cl)cc23)CC1 CHEMBL1093180 Ki 4.7 nM
Nc1nc(N2C[C@H]3CCCN[C@H]3C2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914746 Ki 4.7 nM
N=C(N)SCCc1c[nH]cn1 CHEMBL1490875 Ki 4.862 nM
CC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL443896 pEC50 4.898 nM
O=C(c1cc2ccccc2[nH]1)N1CCNCC1 CHEMBL129660 Ki 4.9 nM
CN1CCN(C(=O)c2cc3c(Cl)c(Cl)ccc3[nH]2)CC1 CHEMBL129436 Ki 5.0 nM
CN1CCN(c2nc(N)nc3cc(-c4ccco4)ccc23)CC1 CHEMBL1935573 Ki 5.0 nM
Cc1cnc(OCCCCC2CCN(C)CC2)cc1-c1nc2c(C)c(F)ccc2[nH]1 CHEMBL3236548 Ki 5.0 nM
CN[C@H]1CCN(c2cnnc(NC3CC4CCC3C4)c2)C1 CHEMBL3393557 Ki 5.0 nM
CN1CCN(c2cc(-c3ccccc3)nc(N)n2)CC1 CHEMBL492884 pKi 5.012 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2ncc(Cl)cc23)C1 CHEMBL1915048 pA2 5.012 nM
CN1CCN(C(=O)c2cc3cc(Cl)cc(N)c3[nH]2)CC1 CHEMBL2047450 pKi 5.012 nM
CN1CCN(c2cc(-c3ccc(N)cc3)nc(N)n2)CC1 CHEMBL3133130 pKi 5.012 nM
CC(C)(C)c1cc(N2CC[C@@H](N)C2)nc(N)n1 CHEMBL3236578 pA2 5.012 nM
Nc1nc2c(c(N3CCNCC3)n1)CCCc1ccc(F)cc1-2 CHEMBL523225 Ki 5.1 nM
CN[C@@H]1CCN(c2nc(N)nc3c2sc2cc(Cl)ccc23)C1 CHEMBL1914792 Ki 5.2 nM
Clc1cccc(N2CCN(CCCCNc3nccc4ccccc34)CC2)c1Cl CHEMBL1223749 Ki 5.2 nM
CNC1CN(c2nc(N)nc3cc(C4CC4)cnc23)C1 CHEMBL2376804 pKi 5.248 nM
CN1CCN(c2nc(NCCS(=O)(=O)N(C)c3ccccc3)c3cc(Cl)ccc3n2)CC1 CHEMBL592663 pKi 5.37 nM
FC(F)(F)c1cccc(N2CCN(CCCCNc3nccc4ccccc34)CC2)c1 CHEMBL1223750 Ki 5.4 nM
Nc1nc(C2CCCC2)cc(N2CC(N)C2)n1 CHEMBL3236558 Ki 5.5 nM
CN1CCN(c2nc3cc(Cl)c(Cl)cc3[nH]c2=O)CC1 CHEMBL260549 Log Ki 5.623 nM
CC(C)(C)CC(=O)c1cccc(Cc2c[nH]cn2)c1 CHEMBL489493 pKi 5.623 nM
CC(C)(C)C#Cc1cccc(Cc2c[nH]cn2)c1 CHEMBL493014 pKi 5.623 nM
Nc1nc(N2CCC[C@H](N)C2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914548 Ki 5.7 nM
Nc1nc2c(c(N3CCNCC3)n1)CCC1=C2[C@@H]2CCCC[C@@H]2O1 CHEMBL519240 pKi 5.754 nM
CN1CCN(c2nc(NCCS(=O)(=O)Nc3ccccc3)c3cc(I)ccc3n2)CC1 CHEMBL592434 pKi 5.754 nM
CN[C@@H]1CCN(c2cc(N)nc(NC(C)C)n2)C1 CHEMBL1770990 Ki 6.0 nM
CN[C@@H]1CCN(c2cc(N)nc(NC3CCCC3)n2)C1 CHEMBL1770959 Ki 6.0 nM
Nc1nc2c(c(N3CCNCC3)n1)CCC1=C2[C@H]2CCCC[C@H]2O1 CHEMBL1935450 Ki 6.0 nM
CN1CCN(C2=Nc3ccc(Cl)cc3Oc3ccccc32)CC1 CHEMBL213912 Ki 6.0 nM
CN[C@@H]1CCN(c2ccnc(NC(C)C)n2)C1 CHEMBL3354815 Ki 6.0 nM
CN[C@@H]1CCN(c2cnnc(NC3CCCC3)c2)C1 CHEMBL3393553 Ki 6.0 nM
CN1CCN(c2cc(NCc3ccccc3Cl)nc(N)n2)CC1 CHEMBL594721 pEC50 6.026 nM
CC(CC(=O)NC(=N)NCCCc1c[nH]cn1)c1cccs1 CHEMBL502339 EC50 6.3 nM
CN1CCN(C(=O)c2cc3c(F)c(Cl)ccc3[nH]2)CC1 CHEMBL2047447 pKi 6.31 nM
CN1CCN(C(=O)c2cc3cc(Cl)cc(F)c3[nH]2)CC1 CHEMBL2047448 pKi 6.31 nM
Cc1cc(Cl)cc2cc(C(=O)N3CCN(C)CC3)[nH]c12 CHEMBL2047449 pKi 6.31 nM
Nc1nccc(NCCNc2cc(-c3cccc(Cl)c3)nc(N)n2)n1 CHEMBL2375757 pKi 6.31 nM
N=C(NCc1cccc(Cl)c1)SCCCc1c[nH]cn1 CHEMBL551790 pEC50 6.31 nM
CNC1CN(c2nc(N)nc3cc(C4CCCC4)cnc23)C1 CHEMBL2376803 pKi 6.457 nM
CN1C[C@@H]2CN(C(=N)c3nc4ccccc4[nH]3)C[C@@H]2C1 CHEMBL1938979 Ki 6.5 nM
Cc1cc(OCCCNCC2CCCNC2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 CHEMBL1084869 EC50 6.9 nM
Cc1cccc2cc(C(=O)N3CCN(C)CC3)[nH]c12 CHEMBL129488 Ki 7.0 nM
Cc1c(F)ccc2[nH]c(C(=O)N3CCN(C)CC3)nc12 CHEMBL120591 Ki 7.0 nM
Nc1nc(N2CCNCC2)c2ccc(-c3ccco3)cc2n1 CHEMBL1935574 Ki 7.0 nM
CCCCNc1cc(N2CC[C@@H](NC)C2)ccn1 CHEMBL3393529 Ki 7.0 nM
N/C(=N\C(=O)CCc1c[nH]c2ccccc12)NCCCc1c[nH]cn1 CHEMBL514641 pEC50 7.079 nM
Nc1nc2c(c(N3CC4CCCNC4C3)n1)CCCCC2c1ccccc1 CHEMBL1077276 pKi 7.079 nM
CNC1CN(c2nc(N)nc3cc(C4CC4)ccc23)C1 CHEMBL2376794 pKi 7.079 nM
CN1CCN(c2nc(NCc3cccs3)c3cc(Cl)ccc3n2)CC1 CHEMBL452847 pKi 7.586 nM
CCN(CC)S(=O)(=O)CCNc1nc(N2CCN(C)CC2)nc2ccc(Cl)cc12 CHEMBL591500 pKi 7.586 nM
Clc1ccc(CNCC[C@@H]2C[C@H]2c2c[nH]cn2)cc1 CHEMBL213886 Ki 7.6 nM
CN1CCN(c2nc(N)nc3c2oc2ccc(Cl)c(Cl)c23)CC1 CHEMBL1914757 Ki 7.7 nM
Nc1nc(N2CCNCC2)c2oc3ccc(Cl)c(Cl)c3c2n1 CHEMBL1914774 Ki 7.7 nM
CN1CCN(C(=O)c2cc3cccc(N)c3[nH]2)CC1 CHEMBL129540 pA2 7.762 nM
N/C(=N/CCc1ccc(I)cc1)SCCCc1cnc[nH]1 CHEMBL498770 Ki 7.8 nM
CN1CCN(C(=O)c2cc3cc(N)ccc3[nH]2)CC1 CHEMBL340740 pA2 7.943 nM
N=C(NCc1ccc(Cl)cc1)SCCCCc1c[nH]cn1 CHEMBL1632409 pKi 7.943 nM
CC(C)/N=C(\S)NCCCCc1c[nH]cn1 CHEMBL306077 pKi 7.943 nM
N=C(NCCCc1c[nH]cn1)NC(=O)CC(c1ccccc1)c1ccccc1 CHEMBL471413 pEC50 7.943 nM
c1nc(CCCn2cc(CC3CCCC3)nn2)c[nH]1 CHEMBL1688976 pKi 7.943 nM
CN[C@@H]1CCN(c2cc(N3CCCC3)nc(N)n2)C1 CHEMBL1770995 pA2 7.943 nM
Nc1nccc(NCCNc2cc(-c3ccccc3)nc(N)n2)n1 CHEMBL2375773 pKi 7.943 nM
CN1CCN(c2cc(-c3ccc([N+](=O)[O-])cc3)nc(N)n2)CC1 CHEMBL3133131 pKi 7.943 nM
CN[C@@H]1CCN(c2cc(C3CC3)nc(N)n2)C1 CHEMBL3236574 pA2 7.943 nM
CN[C@H]1CCN(c2ccnc(NC3CC4CCC3C4)n2)C1 CHEMBL3393548 pA2 7.943 nM
CN1CCN(C(=O)c2cc3cc(Br)ccc3[nH]2)CC1 CHEMBL128613 Ki 8.0 nM
Nc1nc(N2CCCC2)cc(N2CCNCC2)n1 CHEMBL1770160 Ki 8.0 nM
CN[C@@H]1CCN(c2nc(N)nc3c2oc2c(Cl)cc(Cl)cc23)C1 CHEMBL1914785 Ki 8.0 nM
CN[C@@H]1CCN(c2cnnc(NC3CC4CCC3C4)c2)C1 CHEMBL3393556 Ki 8.0 nM
N=C(N)NCCCc1c[nH]cn1 CHEMBL325327 pEC50 8.128 nM
CN1CCN(c2nc(NCCS(=O)(=O)Nc3ccccc3)c3c(C(F)(F)F)cccc3n2)CC1 CHEMBL591496 pKi 8.128 nM
CC1CC(C)(C)N=C(c2cccc(Cc3c[nH]cn3)c2)O1 CHEMBL494982 pKi 8.318 nM
C[C@H](CC(=O)NC(=N)NCCCc1c[nH]cn1)C1CCCCC1 CHEMBL1096430 pEC50 8.318 nM
Cc1cc(C)c2nc(-c3cnc(NCCCC4CCN(C)CC4)nc3C)[nH]c2c1 CHEMBL3301609 Ki 8.4 nM
Cc1ccccc1CNc1cc(N2CCN(C)CC2)nc(N)n1 CHEMBL594731 pEC50 8.511 nM
Cc1nc(N)sc1CCCN/C(N)=N/C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1 CHEMBL2165628 pEC50 8.511 nM
N/C(=N\C(=O)CCCCCCCCC(=O)/N=C(\N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 CHEMBL2165642 pEC50 8.511 nM
CCc1cnc2c(N3CC(NC)C3)nc(N)nc2c1 CHEMBL2376800 pKd 8.511 nM
C[C@@H](NC(=O)/N=C(\N)NCCCc1c[nH]cn1)c1ccccc1 CHEMBL5208722 pKi 8.511 nM
Cc1ccc2[nH]c(-c3ccc(OCCCN4CCCN(C)CC4)cc3Cl)nc2c1C CHEMBL219982 Ki 9.0 nM
Nc1nc(N2CCC[C@@H](N)C2)c2oc3ccc(Cl)cc3c2n1 CHEMBL1914549 Ki 9.1 nM
CCc1cnc2c(N3CC[C@@H](NC)C3)nc(N)nc2c1 CHEMBL2376801 pKi 9.12 nM
CN1CCN(c2nc(NCCS(=O)(=O)N3CCOCC3)c3cc(Cl)ccc3n2)CC1 CHEMBL591250 pKi 9.333 nM
CCc1cnc2c(N3CCN(C)CC3)nc(N)nc2c1 CHEMBL2376799 pKi 9.333 nM
CN1C[C@@H]2CN(C(=N)c3nc4cc(F)c(F)cc4[nH]3)C[C@@H]2C1 CHEMBL1915348 Ki 9.5 nM