CC1(C)[C@@H](O[C@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O[C@@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL441687 IC50 0.4 nM
CC1(C)[C@@H](O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL230006 IC50 1.2 nM
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)N(C)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1269273 IC50 2.9 nM
Cn1c(-c2ccccc2C(F)(F)F)nnc1C12CCC(c3nc(-c4ccc(F)cc4)no3)(CC1)CC2 CHEMBL373257 IC50 3.0 nM
CON[C@@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1271410 IC50 4.9 nM
CCS(=O)(=O)CCC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2 CHEMBL1761313 IC50 7.5 nM
Cc1ccc2c(c1)C(CC(=O)O)CC21CCN(C(=O)NC2C3CC4CC(C3)CC2C4)CC1 CHEMBL597481 IC50 10.0 nM
CC1(C)[C@@H](Oc2noc(=O)[nH]2)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL1689172 IC50 11.0 nM
CN(O)C(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CCC(=O)NC(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1 CHEMBL1689280 IC50 11.0 nM
CON[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1269877 IC50 14.5 nM
CN(O)C(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](Oc6noc(=O)[nH]6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1 CHEMBL1689282 IC50 15.0 nM
CC1(C)[C@@H](O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(NC(N)=O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL1689283 IC50 17.0 nM
CC1(C)C(=O)N(C2CCCCCC2)CC1COc1ccc(C#N)cn1 CHEMBL384650 IC50 20.0 nM
Cn1c(-c2ccccc2C(F)(F)F)nnc1C12CCC(c3noc(C(C)(F)F)n3)(CC1)CC2 CHEMBL2391969 IC50 30.4 nM
CCS(=O)(=O)CC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2 CHEMBL1761321 IC50 31.2 nM
CC1(C)NC(=O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(NC(N)=O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL1689279 IC50 33.0 nM
CC1(C)C(=O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(NC(N)=O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL1689284 IC50 45.0 nM
CC1(C)[C@@H](N)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL425772 IC50 60.0 nM
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)NO)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1270688 IC50 61.1 nM
O=C(C1CCCCC1)N1CC2C3C=CC(CC3)C2C1 CHEMBL4160328 IC50 100.0 nM
O=C(C1CCCCC1)N1CC2C3CCC(CC3)C2C1 CHEMBL4170932 IC50 100.0 nM
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(NC(N)=O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1689173 IC50 104.0 nM
CC1(C)[C@@H](O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)NO)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL1271303 IC50 122.0 nM
CC1(C)[C@@H](OC(=O)CCC(=O)O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL499915 IC50 170.0 nM
CCCCCC12CCC(c3nnc4n3CCCCCC4)(CC1)CC2 CHEMBL200513 IC50 180.0 nM
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(NC(=O)NS(=O)(=O)C(F)(F)F)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1689277 IC50 194.0 nM
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL207413 IC50 201.0 nM
Cc1ccc(C2(c3nnc4n3CCCCCC4)CCCCC2)cc1 CHEMBL256090 IC50 216.0 nM
Clc1ccc(-c2noc(C34CCC(c5nnc6n5CCCCCC6)(CC3)CC4)n2)cc1 CHEMBL372768 IC50 228.0 nM
CO/N=C1\CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1270589 IC50 268.0 nM
COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](Oc6ccccc6C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1 CHEMBL382614 IC50 280.0 nM
CC(O)CCCC12CCC(c3nnc4n3CCCCCC4)(CC1)CC2 CHEMBL1761135 IC50 290.0 nM
CC1(C)C(=O)CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@@H]12 CHEMBL493512 IC50 329.0 nM
O=C1N=C(Nc2ccccc2F)SC1C1CCCC1 CHEMBL240269 IC50 380.0 nM
N#Cc1c(O)nc(SCc2ccccc2)c2c1-c1ccccc1CC2 CHEMBL1911698 IC50 386.0 nM
C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@@]2(C(=O)O)[C@@H]3CC[C@H]4C(C)(C)[C@@H](O)CC[C@@]45C[C@@]35CC[C@]12C CHEMBL2035569 IC50 400.0 nM
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@H](O)C[C@]12C CHEMBL1563246 IC50 400.0 nM
CC(=O)N[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL1270093 IC50 458.0 nM
Cn1c(-c2ccccc2C(F)(F)F)nnc1C12CCC(COc3ccc(Cl)cc3)(CC1)CC2 CHEMBL1761142 IC50 460.0 nM
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C CHEMBL2440888 IC50 490.0 nM
Cc1ccc(C2(c3nnc4n3CCCCCC4)CCCC2)cc1 CHEMBL256515 IC50 503.0 nM
Cc1cccc2c1C(CC(=O)O)CC21CCN(C(=O)NC2C3CC4CC(C3)CC2C4)CC1 CHEMBL597063 IC50 510.0 nM
O=C1N=C(Nc2ccccc2F)SC1C1CCCCC1 CHEMBL240053 IC50 530.0 nM
CC(C)(Oc1ccc(F)cc1Cl)C(=O)N[C@H]1C2CC3CC1C[C@](c1nnn[nH]1)(C3)C2 CHEMBL246678 IC50 550.0 nM
CC(C)(Oc1ccccc1Cl)C(=O)N[C@H]1C2CC3CC1C[C@](C(=O)NS(C)(=O)=O)(C3)C2 CHEMBL246888 IC50 580.0 nM
Clc1ccc(C2(c3nnc4n3CCCCCC4)CCCCC2)cc1 CHEMBL256292 IC50 613.0 nM
CC1(C)C(=O)N([C@H]2C3CC4CC2C[C@](c2nnn[nH]2)(C4)C3)CC1COc1ccc(C(F)(F)F)cn1 CHEMBL218570 IC50 630.0 nM
C=C1[C@H]2C[C@H](O)[C@H]3[C@]4(C)CCC[C@@](C)(NC(=O)NC56CC7CC(CC(C7)C5)C6)[C@H]4CC[C@]3(C2)[C@@H]1O CHEMBL2402465 IC50 700.0 nM
CN(C(=O)N1CCC(CN2C(=O)Nc3ccc(Cl)cc3S2(=O)=O)CC1)C1C2CC3CC(C2)CC1C3 CHEMBL2023587 EC50 720.0 nM
CN(C(=O)N1CCC(CN2C(=O)Nc3ccc(Cl)cc3S2(=O)=O)CC1)C1CCCCCC1 CHEMBL2023585 EC50 860.0 nM
O=C(C1CCCCC1)N1CC2C3C=CC(C4CC34)C2C1 CHEMBL4170544 IC50 1000.0 nM