C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O CHEMBL1405 Potency 1.3 nM
COc1ccc(-c2ccc(=N)n(CCCC(=O)O)n2)cc1 CHEMBL32503 Potency 4.0 nM
Nc1ncnc2c1ncn2[C@@H]1CCCO1 CHEMBL1484751 Potency 4.0 nM
O=C(O)CCCCCC[C@@H]1C(=O)NC(=O)N1CC[C@@H](O)C1CCCCC1 CHEMBL1591294 Potency 5.0 nM
C[C@]12N[C@H](Cc3ccccc31)c1ccccc12 CHEMBL284237 Potency 5.0 nM
COc1ccc(N2C(=O)CSC2c2ccc3c(c2)OCO3)cc1 CHEMBL1415499 Potency 6.3 nM
COCCN(CCOC)c1ncc(Cl)c(C(=O)c2c(C)cc3ccccn23)n1 CHEMBL1340479 Potency 6.3 nM
Cc1c(C(=O)O)oc2ccc(S(=O)(=O)NCCC3=CCCCC3)cc12 CHEMBL1527946 Potency 6.3 nM
CC(=O)C1=C(C)OC(N)=C(C#N)C1c1ccco1 CHEMBL1377070 Potency 6.3 nM
COc1cccc(CNC(=O)C2CCN(S(=O)(=O)N3CCCCC3)CC2)c1 CHEMBL1342226 Potency 6.3 nM
CCOC(=O)c1ccc(NC(=O)CSc2nnc(-c3cccs3)n2CC)cc1 CHEMBL1466656 Potency 6.3 nM
O=c1c(-c2ccccc2)c(O)c2cccc3c2n1CCC3 CHEMBL1531663 Potency 6.3 nM
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC CHEMBL22 Potency 6.3 nM
CCN1C(=S)SC(=O)C1=C1C=C(C)N(CCOC)C(C)=C1 CHEMBL1517382 Potency 10.0 nM
Cc1oc2c(c1C(=O)NCc1cc(C(=O)O)co1)CCCC2 CHEMBL1518120 Potency 10.0 nM
CCn1c(=O)c(C(=O)Nc2cnccn2)c(O)c2ccccc21 CHEMBL1389951 Potency 10.0 nM
CC(C)NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1160723 Potency 12.6 nM
Cc1csc2nc(=O)c(-c3ccccc3)nn12 CHEMBL1498297 Potency 12.6 nM
Cc1cccc(-n2c(S)nnc2CNC(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)c1 CHEMBL1505677 Potency 12.6 nM
C[C@@]12CC[C@H](O)C[C@@H]1CC[C@H]1[C@H]2C[C@@H](O)[C@]2(C)[C@@H](C3=CC(=O)OC3)CC[C@@]12O CHEMBL1397044 Potency 15.8 nM
O=C(O)CCNc1ccc2c(c1)OCCO2 CHEMBL1375429 Potency 15.8 nM
CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3 CHEMBL53 Potency 20.0 nM
COC(=O)CCC(=O)Nc1ccc(S(=O)(=O)N2CCCCCC2)cc1 CHEMBL1606283 Potency 20.0 nM
CCn1c(SCC(=O)N2CCN(c3ccc(Cl)cc3)CC2)nc2ccccc2c1=O CHEMBL1559351 Potency 20.0 nM
NC(=O)c1ccsc1NC(=O)C1CCCN1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL1328320 Potency 25.1 nM
CN1CCN(c2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc2)CC1 CHEMBL1407145 Potency 25.1 nM
COC(=O)C1=C(CN2CCc3ccccc32)NC(=O)NC1c1cc(C)ccc1C CHEMBL1415504 Potency 25.1 nM
NC(=O)/N=N/C(N)=O CHEMBL28517 Potency 25.1 nM
CCCOc1ccc(NC(=O)C2CCCNC2=O)cc1 CHEMBL1604374 Potency 25.1 nM
CC1=C(C)C[S+]([O-])N(S(=O)(=O)c2ccc(Cl)cc2)C1 CHEMBL1364723 Potency 25.1 nM
O=C(CC(C(=O)N1CCc2ccccc21)n1ccnc1)NCc1cccnc1 CHEMBL1417308 Potency 25.1 nM
O=C(/C=C\c1ccc(O)c(O)c1)O[C@@H](Cc1ccc(O)c(O)c1)C(=O)O CHEMBL1315100 Potency 25.1 nM
COc1ccc(S(=O)(=O)N2CCC(O)(c3ccc(Cl)cc3)CC2)cc1 CHEMBL1303974 Potency 25.1 nM
COC(=O)/C=C\c1cc(O)ccc1O CHEMBL277127 Potency 31.6 nM
CCC(Oc1ccccc1)C(=O)Nc1nnc(C(F)(F)F)s1 CHEMBL1331252 Potency 31.6 nM
COC(C)(C)c1cc(C(C)(C)C)nc(N)n1 CHEMBL1359152 Potency 31.6 nM
O=C1C2C3C=CC(CO)(O3)C2C(=O)N1c1ccccc1-c1ccccc1 CHEMBL1470485 Potency 31.6 nM
Cc1occc1C(=O)Nc1cccc(Cn2cccn2)c1 CHEMBL1525273 Potency 31.6 nM
O=C(CNCC1CCCO1)Nc1ccccc1N1CCOCC1 CHEMBL1521483 Potency 31.6 nM
CCc1c(C)nc(N2CCOCC2)nc1O CHEMBL1542929 Potency 31.6 nM
CC(C)OC(=O)CSc1nc2cccnc2n1C1CCCCC1 CHEMBL1352687 Potency 31.6 nM
CCOc1ccc(C(=O)Nc2ccc(N3CCCC3)cc2)cc1 CHEMBL1459530 Potency 31.6 nM
COc1ccc2cc(CCNC(=O)C3CCCC3)c(O)nc2c1 CHEMBL1534369 Potency 31.6 nM
CCOc1ccccc1N1C(=O)CC(Nc2ccc(N3CCOCC3)cc2)C1=O CHEMBL1455912 Potency 31.6 nM
C#CCN(C)CCCOc1ccc(Cl)cc1Cl CHEMBL8706 Potency 31.6 nM
COC(=O)N1CCC2(CCN(C(=O)Nc3cccc(C#N)c3)CC2)CC1 CHEMBL1317244 Potency 31.6 nM
O=S(=O)(Nn1cnnc1)c1ccccc1Cl CHEMBL1422370 Potency 31.6 nM
O=C(O)Cc1nc[nH]c1C(=O)O CHEMBL1574297 Potency 31.6 nM
COc1ccc(OC)c(Nc2ncnc3c2cnn3-c2ccccc2)c1 CHEMBL1613087 Potency 31.6 nM
CCOC(=O)C1CCCN(C(=O)c2cncc(Br)c2)C1 CHEMBL1349168 Potency 31.6 nM
O=C(CCN1C(=O)c2ccccc2C1=O)OCn1nnc2ccccc2c1=O CHEMBL1507086 Potency 31.6 nM
CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C)c(C)c2C)CC1 CHEMBL1451481 Potency 31.6 nM
Cc1ccc2nsnc2c1S(=O)(=O)NCc1ccc2c(c1)OCO2 CHEMBL1528746 Potency 39.8 nM
CCOC(=O)/C=C1\SCC(=O)N1CC(=O)c1ccc[nH]1 CHEMBL1559657 Potency 39.8 nM
O=C(CN1CCN(S(=O)(=O)c2ccccc2)CC1)Nc1cccc(C(F)(F)F)c1 CHEMBL1477586 Potency 39.8 nM
CN(C)/C=N/c1cnc(C(=O)c2ccc(Cl)cc2)n1C CHEMBL3196261 Potency 39.8 nM
Oc1ccc2cc(SSc3ccc4cc(O)ccc4c3)ccc2c1 CHEMBL1489064 Potency 39.8 nM
C=C(C)COc1ccc(-c2n[nH]cc2Oc2ccccc2OCC)c(O)c1 CHEMBL1477778 Potency 39.8 nM
NC(=O)c1c(NC(=O)CSc2nnc(-c3ccccc3)n2CC2CCCO2)sc2c1CCC2 CHEMBL1368329 Potency 39.8 nM
C[C@H](NC(=O)C1(c2ccccc2)CCN(C(=O)[C@H]2CSCN2C(=O)OC(C)(C)C)CC1)C(=O)O CHEMBL1369532 Potency 39.8 nM
O=C(CCC(=O)N1CCc2ccccc21)Nc1ccccc1 CHEMBL1382779 Potency 39.8 nM
CC(=O)Nc1cccc(-c2csc(NCc3ccco3)n2)c1 CHEMBL1523561 Potency 39.8 nM
N#CC1=C(N)Oc2c(oc(CO)cc2=O)C1c1cccs1 CHEMBL1303786 Potency 39.8 nM
Oc1cc2c(c(Cl)c1O)CCNC[C@H]2c1ccccc1 CHEMBL1317463 Potency 39.8 nM
CC1CCCN(c2nc3ccccc3nc2C(C#N)C(=O)OC2CCCCC2)C1 CHEMBL1384420 Potency 39.8 nM
CN(C)C(=S)SSC(=S)N(C)C CHEMBL120563 Potency 50.1 nM
O=C(O)c1ccc(SSc2ccc(C(=O)O)cn2)nc1 CHEMBL1161936 Potency 50.1 nM
O=C(O)/C=C\c1ccc(O)c(O)c1 CHEMBL1320034 Potency 50.1 nM
O=C(O)c1cc(O)c(O)c(O)c1 CHEMBL288114 Potency 50.1 nM
CCOC(=O)C1CCN(C(=O)c2cn(C)c(=O)c3cc(OC)c(OC)cc23)CC1 CHEMBL1582814 Potency 50.1 nM
Cc1ccc(C(=O)NCc2occc2C(=O)O)o1 CHEMBL1417158 Potency 50.1 nM
Oc1cc2c(cc1O)[C@H]1c3ccccc3CN[C@H]1CC2 CHEMBL1224528 Potency 63.1 nM
CCn1c2ccccc2c2nc3cc(S(=O)(=O)N4CCOCC4)ccc3nc21 CHEMBL1470492 Potency 63.1 nM
Oc1cc2c(cc1O)[C@H]1c3ccc(O)c(O)c3OC[C@@]1(O)C2 CHEMBL1448387 Potency 63.1 nM
O=C1C(SCCO)=C(SCCO)C(=O)c2ccccc21 CHEMBL429095 Potency 63.1 nM
OC1(c2cccnc2)CC2CCC(C1)N2Cc1nnnn1Cc1ccccc1 CHEMBL1347058 Potency 63.1 nM
COC(=O)[C@@H](N)Cc1ccc(O)c(O)c1 CHEMBL1328898 Potency 63.1 nM
COCCn1c(=N)c(C(=O)NCCc2ccccc2)cc2c(=O)n3cccc(C)c3nc21 CHEMBL1489634 Potency 63.1 nM
CCOC(=O)c1c(NC(=O)CN2CCN(c3ccccn3)CC2)sc2c1CCCC2 CHEMBL1421985 Potency 63.1 nM
COc1ccc2nc(O)c(CN(CC3CCCO3)C(=O)Nc3ccc(F)cc3)cc2c1 CHEMBL1348280 Potency 63.1 nM
COc1ccc(C[C@@](C)(N)C(=O)O)cc1OC CHEMBL1317133 Potency 63.1 nM
CNc1ccc(O)cc1 CHEMBL1303139 Potency 63.1 nM
[O-][S+](c1ccccc1)c1ccc2nnnn2n1 CHEMBL271023 Potency 63.1 nM
COc1ccc(C(=O)CSc2nc3nc(C)cc(C)n3n2)cc1OC CHEMBL1608006 Potency 63.1 nM
Cc1ccc(NC(=O)CC2SC3=NCCCN3C2=O)c(C)c1 CHEMBL1375938 Potency 79.4 nM
CC1(C)C(=O)C2(CCCCC2)C(=O)OC1c1ccc(O)cc1 CHEMBL1587888 Potency 79.4 nM
O=C1C2CC=CCC2C(=O)N1SC(Cl)(Cl)Cl CHEMBL388676 Potency 79.4 nM
Cc1c(C(=O)O)c(O)cc2c1C(=O)c1c(O)c([C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)c(O)c1C2=O CHEMBL1366408 Potency 79.4 nM
COc1ccc(OCC(=O)N2CCN(Cc3c[nH]c4ccccc34)CC2)cc1 CHEMBL1412835 Potency 79.4 nM
CC1(C)OCC(CSC2=C(SCC3COC(C)(C)O3)C(=O)c3ncccc3C2=O)O1 CHEMBL1596675 Potency 79.4 nM
O=C(Nc1ccc(O)c(Cl)c1)Nc1nc2ccc(-c3nnn[nH]3)cc2s1 CHEMBL5441071 IC50 95.0 nM
NC[C@@H]1O[C@H](c2ccccc2)Cc2c1ccc(O)c2O CHEMBL86931 Potency 100.0 nM
Cc1cc(NCCN2CCCCC2)n2c(nc3ccccc32)c1C#N CHEMBL1575770 Potency 100.0 nM
CCCn1nc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc2c1=O CHEMBL1521142 Potency 100.0 nM
C[C@H](N)[C@H](O)c1ccc(O)c(O)c1 CHEMBL677 Potency 100.0 nM
C[C@@](N)(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL1452561 Potency 100.0 nM
O=C(O)c1cccc(SSc2cccc(C(=O)O)c2)c1 CHEMBL1376178 Potency 100.0 nM
CCOC(=O)c1sc(N)c(C(=O)Nc2ccc(C)cc2C)c1C CHEMBL1360345 Potency 100.0 nM
CC(C)(C)c1cc(Br)c(O)c(CN(Cc2cc(C(C)(C)C)cc(Br)c2O)C2CCCCC2)c1 CHEMBL1331618 Potency 100.0 nM
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O CHEMBL510539 Potency 100.0 nM
CC(C)NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL2062275 Potency 100.0 nM
Oc1ccc([C@@H]2CNCCc3c2cc(O)c(O)c3Cl)cc1 CHEMBL1161520 Potency 100.0 nM
O=C(COC(=O)c1ccc(=O)n(Cc2ccccc2)n1)Nc1ccc2c(c1)OCCO2 CHEMBL1383927 Potency 100.0 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(N)=S CHEMBL77030 Potency 100.0 nM
O=C1C=CC(=O)C2=C1C1c3ccccc3C2c2ccccc21 CHEMBL1474701 Potency 100.0 nM
C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL459 Potency 125.9 nM
Cc1cccc(N2CCN(C(=O)Cn3sc4nc(C)cc(C)c4c3=O)CC2C)c1 CHEMBL1481546 Potency 125.9 nM
C[C@@H](CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1 CHEMBL1367478 Potency 125.9 nM
CCc1ccc2oc(=O)cc(CN3CCCCC3C)c2c1 CHEMBL1369619 Potency 125.9 nM
COc1ccc(OC)c(Nc2nc(-c3ccc(O)c(O)c3)cs2)c1 CHEMBL1419335 Potency 125.9 nM
Oc1cccc2ccc(SSc3ccc4cccc(O)c4n3)nc12 CHEMBL239439 Potency 125.9 nM
NC(=O)c1c(N)sc2c1CCCCC2 CHEMBL1493884 Potency 125.9 nM
Clc1ccc(C(c2ccc(Cl)cc2)[n+]2ccn(C[C@@H](OCc3ccc(Cl)cc3Cl)c3ccc(Cl)cc3Cl)c2)cc1 CHEMBL1594216 Potency 125.9 nM
O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1392315 Potency 125.9 nM
C[C@H](Cc1ccc(O)c(O)c1)[C@@H](C)Cc1ccc(O)c(O)c1 CHEMBL313972 Potency 125.9 nM
O=C1C(Cl)=C(Cl)C(=O)C(Cl)=C1Cl CHEMBL192627 Potency 125.9 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL50 Potency 125.9 nM
O=C(O)CCSc1nnc(-c2ccc3c(c2)OCO3)o1 CHEMBL1319810 Potency 125.9 nM
Cc1cccc([C@@H]2CN(C)CCc3c2cc(O)c(O)c3Cl)c1 CHEMBL1416789 Potency 125.9 nM
O=S(=O)(/C=C/c1ccccc1)n1cnc2ccccc21 CHEMBL1544475 Potency 125.9 nM
O=C1C=CC2=C3c4cc(O)c(O)cc4C[C@@]3(O)COC2=C1O CHEMBL372505 Potency 125.9 nM
Oc1cc2c(cc1O)[C@H](c1ccccc1)CNCC2 CHEMBL284746 Potency 125.9 nM
Cc1cc(C)nc(/N=c2/ssnc2Cl)c1 CHEMBL1968355 Potency 125.9 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 Potency 125.9 nM
COc1ccccc1OCC(=O)Nc1ccc(O)cc1C(=O)O CHEMBL1349592 Potency 125.9 nM
CC(C)NCC(O)c1ccc(O)c(O)c1 CHEMBL1711 Potency 125.9 nM
O=C(CSc1nnc(Nc2ccccc2)s1)NCc1ccco1 CHEMBL1601992 Potency 125.9 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2ccccc12 CHEMBL122701 Potency 125.9 nM
CCn1cc(C(=O)[O-])c(=O)c2ccc(C)nc21 CHEMBL1255939 Potency 125.9 nM
COc1c(Br)cc(Br)cc1C(=O)O CHEMBL1602522 Potency 158.5 nM
CC(=O)N1CCc2c(sc(NC(=O)c3ccc4c(c3)OCCO4)c2C#N)C1 CHEMBL1555967 Potency 158.5 nM
O=S1(=O)C=C(Sc2nnc(-c3ccccc3)o2)c2ccccc21 CHEMBL1602759 Potency 158.5 nM
CC1=C(SCCC#N)S/C(=C2\SC(C)=C(SCCC#N)S2)S1 CHEMBL1407483 Potency 158.5 nM
C=CCN1CCc2cc(O)c(O)cc2[C@H](c2ccccc2)C1 CHEMBL286120 Potency 158.5 nM
O=C(Oc1cccc(Oc2ccccc2)c1)N1CCOCC1 CHEMBL1537005 Potency 158.5 nM
CCN(CC)C(=S)SSC(=S)N(CC)CC CHEMBL964 Potency 158.5 nM
N[C@@H](CSS(=O)(=O)O)C(=O)O CHEMBL457665 Potency 158.5 nM
C[C@@](Cc1ccc(O)c(O)c1)(NN)C(=O)O CHEMBL1201236 Potency 158.5 nM
CCOc1cccc(NC(=O)CC#N)c1 CHEMBL1447084 Potency 158.5 nM
CCOC(=O)Cc1csc(NC(=O)CSc2nnc(C3CC3)n2C)n1 CHEMBL1511167 Potency 158.5 nM
N#CC(C#N)=Cc1ccc([N+](=O)[O-])c(O)c1 CHEMBL77387 Potency 158.5 nM
COc1ccc(N2CCN(C(=O)CSc3nnc(-c4cccnc4)n3-c3ccccc3)CC2)cc1 CHEMBL1334873 Potency 158.5 nM
CC1CCC2C(C1)c1sc(O)nc1SC2(C)C CHEMBL1544013 Potency 158.5 nM
O=C(CCN1CCCCC1)c1ccc2c(c1)OCCO2 CHEMBL1561369 Potency 158.5 nM
Cc1cc(C)c2c(=O)n(CC(=O)NCCCN3CCOCC3)sc2n1 CHEMBL1499996 Potency 158.5 nM
Cc1cc(N2CCN(c3nc4ccccc4s3)CC2)n2ncnc2n1 CHEMBL1361461 Potency 158.5 nM
N#CC(C#N)=C/C(N)=C(/C#N)c1cc(O)c(O)c(O)c1 CHEMBL1376723 Potency 158.5 nM
O=c1ccsn1Cc1ccccc1 CHEMBL572994 Potency 158.5 nM
CN1C(=O)C2(OCC(COc3ccc(Cl)cc3)O2)c2ccccc21 CHEMBL1562591 Potency 158.5 nM
Cc1ccc(-c2noc(CN3CCN(Cc4ccccc4)CC3)n2)cc1 CHEMBL1530122 Potency 158.5 nM
CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c(O)c1 CHEMBL1472703 Potency 158.5 nM
O=C(CSc1nc2ccccc2[nH]1)c1cccs1 CHEMBL1384293 Potency 158.5 nM
CCOC(=O)c1sc(NC(=O)CSc2nnc(Cc3ccccc3)o2)c(C#N)c1C CHEMBL1304359 Potency 158.5 nM
O=c1c[n+]([O-])c2ccccc2n1OCc1c(F)cccc1F CHEMBL1410325 Potency 199.5 nM
O=c1c(-c2ccc(Cl)cc2)nc2cnc(N3CCOCC3)nc2n1Cc1ccc(F)cc1 CHEMBL1358671 Potency 199.5 nM
CCOC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(C)C(=O)O)c(OC)c1 CHEMBL1457981 Potency 199.5 nM
CN(CCc1ccccn1)S(=O)(=O)c1ccccc1F CHEMBL1336348 Potency 199.5 nM
O=C1Oc2ccccc2C(=O)/C1=C/Nc1nc(-c2ccc(O)c(O)c2)cs1 CHEMBL1514547 Potency 199.5 nM
N[C@@H](Cc1ccnnc1)C(=O)O CHEMBL1359852 Potency 199.5 nM
CC(=O)Oc1ccc(N2C(=O)C3C(C2=O)C2(C)C=CC3(C)O2)cc1 CHEMBL1486729 Potency 199.5 nM
Cc1cc(C)c2c(=O)n(CC(=O)N3CCC(N4CCCCC4)CC3)sc2n1 CHEMBL1471841 Potency 199.5 nM
Cc1cc(CN2CCOCC2)c(O)c(C2(C)CCCCC2)c1 CHEMBL1439019 Potency 199.5 nM
O=S(=O)(c1cccs1)N1CN(CC2CCCO2)c2nc3ccccc3nc21 CHEMBL1576577 Potency 199.5 nM
Nn1c(SCc2nc3ccccn3c2Br)nnc1-c1cccnc1 CHEMBL1408532 Potency 199.5 nM
CN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3 CHEMBL1400569 Potency 199.5 nM
CN(C)C(CNC(=O)CN1C(=O)NC2(CCc3ccccc32)C1=O)c1ccco1 CHEMBL1607712 Potency 199.5 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL422 Potency 199.5 nM
Cc1ccc2cc(CN(CC3CCCO3)C(=O)C(C)C)c(O)nc2c1 CHEMBL1506086 Potency 199.5 nM
CCC(=O)c1ccccc1OCCSc1nc(C)cc(O)n1 CHEMBL1412993 Potency 199.5 nM
O=C(OCC(=O)N1CCN(c2ccccc2)CC1)C1=COCCO1 CHEMBL1338389 Potency 199.5 nM
O=CN1CCN(C[C@H](O)CN2CCCCC2)CC1 CHEMBL1566341 Potency 199.5 nM
Cc1ccc(SCC(=O)NCc2ccco2)cc1 CHEMBL1584677 Potency 199.5 nM
O=C1C(Cl)=C(N2CCOCC2)C(=O)N1c1ccccc1Cl CHEMBL1334552 Potency 199.5 nM
O=C1NC(=O)C(c2ccccc2[N+](=O)[O-])=C1Nc1ccc(O)c(Cl)c1 CHEMBL322970 Potency 199.5 nM
CN1CCN(C(=O)c2sc(=S)n(-c3ccccc3)c2N)CC1 CHEMBL1304193 Potency 199.5 nM
O=c1cc(-c2cccc(O)c2O)oc2ccccc12 CHEMBL242171 Potency 199.5 nM
Cc1cc(C)c2c(=O)n(CC(=O)N3CCC(Cc4ccccc4)CC3)sc2n1 CHEMBL1367163 Potency 199.5 nM
CN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3 CHEMBL1435422 Potency 199.5 nM
O=C(Nc1ccc(O)c(C(F)(F)F)c1)Nc1nc2ccc(C(=O)O)cc2s1 CHEMBL5433229 IC50 250.0 nM
CC(=O)N1CCN(c2ccc(Oc3ncnc4sccc34)cc2)CC1 CHEMBL1409060 Potency 251.2 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 Potency 251.2 nM
N#Cc1cnn(Cc2ccccc2)c1/N=C/N1CCOCC1 CHEMBL3192836 Potency 251.2 nM
Cc1cc(Br)c(S(=O)(=O)n2nnc3ccccc32)cc1C CHEMBL1359146 Potency 251.2 nM
COC(=O)Oc1nsnc1N1CCOCC1 CHEMBL1581518 Potency 251.2 nM
COc1ccc(OC)c(CCNC(=O)Cn2sc3nc(C)cc(C)c3c2=O)c1 CHEMBL1510394 Potency 251.2 nM
C=CCN1CCc2c(cc(O)c(O)c2Cl)C(c2cccc(C)c2)C1 CHEMBL556024 Potency 251.2 nM
CCc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)cc1 CHEMBL1517350 Potency 251.2 nM
COc1ccc(OC)c2c(=S)c3ccccc3[nH]c12 CHEMBL1331734 Potency 251.2 nM
CCOC(=O)NC1(Nc2ccc(Cl)cn2)Oc2ccccc2O1 CHEMBL1380958 Potency 251.2 nM
CCOC(=O)C1CCCN(C(=O)Cn2sc3nc(C)cc(C)c3c2=O)C1 CHEMBL1504634 Potency 251.2 nM
O=S(=O)(O)c1cc(O)ccc1O CHEMBL1514715 Potency 251.2 nM
O=c1cc(O)cc(/C=C\c2ccc(O)c(O)c2)o1 CHEMBL1336985 Potency 251.2 nM
Cc1onc(-c2ccccc2)c1C(=O)Nc1nnc(COc2ccc(Cl)cc2)s1 CHEMBL1411681 Potency 251.2 nM
S=C(S)N1CCCC1 CHEMBL399491 Potency 251.2 nM
CC(C)(C)c1ccc(O)c(O)c1 CHEMBL220845 Potency 251.2 nM
C[C@@H]1NCCc2cc(O)c(O)cc21 CHEMBL1195032 Potency 251.2 nM
c1ccc2[nH]c(SN3CCOCC3)nc2c1 CHEMBL1490628 Potency 251.2 nM
Cc1cc(=O)oc2c(N)c(O)ccc12 CHEMBL1370010 Potency 251.2 nM
CN1[C@@H]2CC[C@H]1CC(OC(=O)[C@@H](O)c1ccccc1)C2 CHEMBL1452657 Potency 251.2 nM
COc1ccc(CC(=O)Nc2ccc(-c3nnc(-c4ccc(C)cc4)o3)cc2)cc1 CHEMBL1566536 Potency 251.2 nM
C/N=c1\nc(-c2ccccc2)n(-c2ccccc2)s1 CHEMBL161867 Potency 251.2 nM
CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 CHEMBL1412731 Potency 251.2 nM
CCOP(=O)(OCC)[C@@H](Nc1nc2ccc(OC)cc2s1)c1ccc(O)c(C(=O)OC)c1 CHEMBL4114885 Kd 256.0 nM
COc1ccc2nc(N[C@@H](c3ccccc3O)P(=O)(OC)OC)sc2c1 CHEMBL4107064 Kd 264.0 nM
COc1ccc2nc(N[C@@H](c3ccc(F)cc3)P(=O)(OC)OC)sc2c1 CHEMBL4109182 Kd 264.0 nM
NC(=O)Nc1ccc2nc(NC(=O)Nc3ccc(O)c(Cl)c3)sc2c1 CHEMBL5419196 IC50 270.0 nM
CS(=O)(=O)Nc1ccc2nc(NC(=O)Nc3ccc(O)c(Cl)c3)sc2c1 CHEMBL5403203 IC50 290.0 nM
COc1ccc2nc(N[C@@H](c3ccc(O)cc3)P(=O)(OC)OC)sc2c1 CHEMBL4114467 Kd 291.0 nM
O=C(O)c1cc2c(cc1S(=O)(=O)O)[C@H]1[C@@H](C3[C@H]2[C@@]2(Cl)C(Cl)=C(Cl)[C@@]3(Cl)C2(Cl)Cl)[C@]2(Cl)C(Cl)=C(Cl)[C@]1(Cl)C2(Cl)Cl CHEMBL2373284 Potency 316.2 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 Potency 316.2 nM
Oc1c([C@H](Nc2ccccn2)c2ccccc2)ccc2cccnc12 CHEMBL1450821 Potency 316.2 nM
Oc1ccc([C@@H]2CNCc3sccc32)cc1O CHEMBL407489 Potency 316.2 nM
CCCCc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)s1 CHEMBL1469840 Potency 316.2 nM
O=C(CSc1nnnn1-c1ccccc1)Nc1nsc(-c2ccc(Cl)cc2)n1 CHEMBL1491602 Potency 316.2 nM
COc1ccc(N(C(=O)COc2ccccc2)C2C=CS(=O)(=O)C2)c(OC)c1 CHEMBL1575793 Potency 316.2 nM
Cc1ccc(-n2sc3ccccc3c2=O)cc1S(=O)(=O)N1CCCCC1 CHEMBL1423690 Potency 316.2 nM
COc1cc(CO)cc(Br)c1OCc1cccnc1 CHEMBL1489289 Potency 316.2 nM
Cc1c(C(=O)c2no[n+]([O-])c2C(=O)c2cnn(C)c2C)cnn1C CHEMBL1446802 Potency 316.2 nM
O=c1cc(-c2ccccc2O)oc2c(O)c(O)ccc12 CHEMBL244707 Potency 316.2 nM
CC(CCC(=O)O)(c1cc(Br)c(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1 CHEMBL1611308 Potency 316.2 nM
Clc1ccc(-c2nn3c(Cn4cnc5ccccc54)nnc3s2)c(Cl)c1 CHEMBL1511200 Potency 316.2 nM
Cc1ccc(-c2nc3cc(NC(=O)C(C)C)ccc3o2)cc1 CHEMBL1498591 Potency 316.2 nM
O=c1oc2c3c4c(cc2c2c1CCC2)OCCN4CCC3 CHEMBL1489758 Potency 316.2 nM
O=c1c2ccccc2sn1-c1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1 CHEMBL1371792 Potency 316.2 nM
CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@@H]2SC1 CHEMBL1474278 Potency 316.2 nM
Cc1cc(C)c2c(=O)n(CC(=O)NCCCN3CCN(c4ccccc4F)CC3)sc2n1 CHEMBL1302139 Potency 316.2 nM
C[C@](Cc1ccc(O)c(O)c1)(NN)C(=O)O CHEMBL1417392 Potency 316.2 nM
Cc1nc2c(C(=O)N3CCN(c4ccccn4)CC3)cnn2c(C)c1Cc1cccc(Cl)c1 CHEMBL1607113 Potency 316.2 nM
O=C1NCN(c2ccccc2)C12CCNCC2 CHEMBL309711 Potency 316.2 nM
CCC1CCCCN1CCCNC(=O)C1CCN(S(=O)(=O)N2CCCCC2)CC1 CHEMBL1584569 Potency 316.2 nM
N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O CHEMBL1009 Potency 316.2 nM
C/C=C1\C(=O)C[C@@H]2[C@@H]3CCC4=CC(=O)CC[C@@]4(C)[C@H]3CC[C@@]12C CHEMBL1452876 Potency 316.2 nM
Nc1c(N2CCCC2)cc(Cl)c2nonc12 CHEMBL1379048 Potency 316.2 nM
Oc1c(CN2CCOCC2)ccc(CN2CCOCC2)c1O CHEMBL1449373 Potency 316.2 nM
C=CCN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3 CHEMBL319557 Potency 316.2 nM
Cc1nc(N2CCCC2)c2ccsc2n1 CHEMBL1485331 Potency 316.2 nM
CN(C)c1nc(N(C)C)nc(N(C)C)n1 CHEMBL1455 Potency 316.2 nM
COc1ccc2nc(N[C@@H](c3ccc[nH]3)P(=O)(OC)OC)sc2c1 CHEMBL4110134 Kd 380.0 nM
O=C(O)CSc1nnc(C2CC2)n1-c1ccccc1 CHEMBL1495233 Potency 398.1 nM
CC1=C(Br)C(=O)C(C)=C(Br)C1=O CHEMBL1566105 Potency 398.1 nM
Oc1ccc(O)cc1 CHEMBL537 Potency 398.1 nM
CC1CCCN(c2nc3ccccc3nc2C(C#N)S(=O)(=O)c2ccccc2)C1 CHEMBL1391798 Potency 398.1 nM
COC(=O)/C=c1/sc2nc3ccccc3n2c1=O CHEMBL1975289 Potency 398.1 nM
O=C(Oc1ccc2oc(=O)sc2c1)c1ccccc1F CHEMBL1565329 Potency 398.1 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1CC[C@@](OC(=O)/C=C/c2ccc(O)c(O)c2)(C(=O)O)[C@@H](O)[C@@H]1O CHEMBL1533705 Potency 398.1 nM
Cc1cc(O)c(-c2cc(O)c(C)cc2O)cc1O CHEMBL1527565 Potency 398.1 nM
CNC[C@@H](SC)c1ccc(O)c(O)c1 CHEMBL1447738 Potency 398.1 nM
Nc1cc(S(N)(=O)=O)ccc1SSc1ccc(S(N)(=O)=O)cc1N CHEMBL120806 Potency 398.1 nM
COc1cc(C2c3sc(O)nc3SC3C4CCC(C4)C23)ccc1O CHEMBL1400386 Potency 398.1 nM
Cc1cc(O)c2c(c1)C(=O)c1cc(O)cc(O)c1C2=O CHEMBL289277 Potency 398.1 nM
CCOC(=O)c1nn(-c2ccccc2)c(=O)c2c(N)scc12 CHEMBL461431 Potency 398.1 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)O)cc3)[nH]c2c1=O CHEMBL8565 Potency 398.1 nM
Nc1nc2c(c3c1c(=O)oc1ccccc13)CCCCC2 CHEMBL1558422 Potency 398.1 nM
Cc1ccnc(-n2sc3ccccc3c2=O)n1 CHEMBL608699 Potency 398.1 nM
CN1CCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2CCSc2nc3ccccc3s2)CC1 CHEMBL1507183 Potency 398.1 nM
O=c1cc(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL28 Potency 398.1 nM
CC1(C)C2CCC1(CS(=O)(=O)N1CCCc3ccccc31)C(=O)C2 CHEMBL1566540 Potency 398.1 nM
O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCCCC2)cc1 CHEMBL1530439 Potency 398.1 nM
CC(=O)C(Sc1ncnc2c1nnn2-c1ccc(F)cc1)C(=O)N(C)C CHEMBL1484933 Potency 398.1 nM
COC(=O)c1cc([C@H](Nc2nc3ccc(OC)cc3s2)P(=O)(OC)OC)ccc1O CHEMBL4107342 Kd 496.0 nM
N#Cc1cc2cc3c(cc2nc1N1CCOCC1)OCO3 CHEMBL1564877 Potency 501.2 nM
O=C(O)CCCCn1cnc2c(S)ncnc21 CHEMBL1530801 Potency 501.2 nM
COC(=O)c1cc(Br)c(=O)n(-c2ccc(C(C)=O)cc2)c1 CHEMBL1548276 Potency 501.2 nM
Oc1ncnc2c1sc(=S)n2-c1ccccc1 CHEMBL1409384 Potency 501.2 nM
COC(=O)c1cc(S(=O)(=O)N2CCC(C)CC2)ccc1F CHEMBL1536946 Potency 501.2 nM
Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c1nc2ccccc2[nH]1 CHEMBL480 Potency 501.2 nM
COc1ccc(-c2cc3nc4c(c(O)n3n2)CCC4)cc1 CHEMBL1587744 Potency 501.2 nM
CCn1c(N)c(C(=O)NC)sc1=S CHEMBL1300266 Potency 501.2 nM
O=S1(=O)C=C(Sc2nc3ccccc3s2)c2ccccc21 CHEMBL1370884 Potency 501.2 nM
CC(=O)Oc1ccc(N2C(=O)C3C4C=CC(O4)C3C2=O)cc1 CHEMBL1360146 Potency 501.2 nM
NCCc1ccc(O)c(O)c1 CHEMBL59 Potency 501.2 nM
O=C(O)Cc1ccc(O)c(O)c1 CHEMBL1284 Potency 501.2 nM
CCCN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3 CHEMBL330274 Potency 501.2 nM
Cc1ccc(-n2c(N)c(-c3nc4ccccc4n3C)sc2=S)cc1 CHEMBL1337364 Potency 501.2 nM
CCOC(=O)C(C(C)=O)c1c(Br)c(O)c(O)c2c(C(=O)c3ccc(C)cc3)coc12 CHEMBL1331809 Potency 501.2 nM
Oc1c(Cl)cc(Cl)c2c1NCCC2 CHEMBL1411897 Potency 501.2 nM
C=C(C)COc1ccc2c(C)c(CC(=O)OC)c(=O)oc2c1C CHEMBL1427175 Potency 501.2 nM
NS(=O)(=O)c1ccc(NCc2nc3ccccc3[nH]2)cc1 CHEMBL1443986 Potency 501.2 nM
Nc1nc(N2CCCCC2)nc2ccccc12 CHEMBL1505849 Potency 501.2 nM
CN(C)Cc1cc(O)c(O)c(CN(C)C)c1 CHEMBL1535057 Potency 501.2 nM
CC(C)C[C@H](N)c1nnc(S(=O)(=O)Cc2cccc(F)c2)o1 CHEMBL1401211 Potency 501.2 nM
Cc1ccc(-n2c(O)nc3c(C(N)=O)nc(-c4ccc(C)o4)nc32)cc1 CHEMBL1456676 Potency 501.2 nM
CC(=O)NCCc1ccc(O)c(O)c1 CHEMBL137743 Potency 501.2 nM
OC(COc1ccc2cc(Br)ccc2c1)CN1CCN(c2ccccn2)CC1 CHEMBL1417914 Potency 501.2 nM
CC1(C)Cc2c(C#N)c(N)sc(=S)c2CS1 CHEMBL3392040 Potency 501.2 nM
N#Cc1c2c(c(=S)n(-c3ccccc3)c1N)CCCC2 CHEMBL3191286 Potency 501.2 nM
Cc1ccc2nc3c(cc(C#N)c(=O)n3-c3nccs3)c(=O)n2c1 CHEMBL1501839 Potency 501.2 nM
NC(=O)SCC(=O)Nc1ccc(Cl)cc1 CHEMBL1330520 Potency 501.2 nM
NCCNC(=S)S CHEMBL1528688 Potency 501.2 nM
CC(C)Nc1ccc(Nc2ccccc2)cc1 CHEMBL1449018 Potency 501.2 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H](C(=O)O)[C@@H](OC(=O)/C=C/c1ccc(O)c(O)c1)C(=O)O CHEMBL282731 Potency 501.2 nM
CN(C)CN1CSC(=S)N(CN(C)C)C1 CHEMBL1410399 Potency 501.2 nM
COc1cc2c(cc1O)[C@@H](c1cc(O)c(O)c(OC)c1)[C@@](O)(C(=O)O)[C@@H](CO)[C@@H]2O CHEMBL1354249 Potency 501.2 nM
CCCCS(=O)(=O)/C=C\C=C/S(=O)(=O)CCCC CHEMBL1563483 Potency 501.2 nM
O=C(CSC1=NS(=O)(=O)c2ccccc21)Nc1ccccc1 CHEMBL1547321 Potency 501.2 nM
Nc1nc(-c2cccs2)c(NC(=O)c2ccccc2)s1 CHEMBL1441938 Potency 501.2 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL1520590 Potency 501.2 nM
N#CSCSC#N CHEMBL1524617 Potency 501.2 nM
CN[C@@H](C)[C@@H](O)c1ccccc1 CHEMBL1590 Potency 631.0 nM
CCNc1ncc2nc(-c3ccc(F)cc3)c(=O)n(C[C@H]3CCCO3)c2n1 CHEMBL1354901 Potency 631.0 nM
C=C(CC(=O)O)C(=O)O CHEMBL1565425 Potency 631.0 nM
Cc1nn(-c2ccc(F)cc2)c2c1cc(C#N)c1nc3ccccc3n12 CHEMBL1529320 Potency 631.0 nM
Cc1c2cnccc2c(C)c2c1c1ccccc1n2CCOC(=O)c1ccccc1 CHEMBL1374334 Potency 631.0 nM
CCNc1oc(-c2cccc3ccccc23)nc1C#N CHEMBL1571456 Potency 631.0 nM
Cc1ccc(-c2nnc(-c3ccc(Br)cc3)o2)o1 CHEMBL1482449 Potency 631.0 nM
Cn1c(C(=O)NCCCN2CCCC2=O)cc2c(=O)n3ccccc3nc21 CHEMBL1531157 Potency 631.0 nM
COc1ccc2c(=O)c(OC)c(-c3ccccc3)oc2c1 CHEMBL1449187 Potency 631.0 nM
Cc1ccc2nc3c(cc(C#N)c(=O)n3CC3CCCO3)c(=O)n2c1 CHEMBL1404772 Potency 631.0 nM
Cn1c(=O)c2c(nc(/C=C\c3cccc(Cl)c3)n2C)n(C)c1=O CHEMBL1511958 Potency 631.0 nM
Cc1cc(OCC(=O)C(C)(C)C)c2c(C)c(C)c(=O)oc2c1 CHEMBL1367862 Potency 631.0 nM
Cn1c(C(=O)NCCC2=CCCCC2)cc2c(=O)n3ccccc3nc21 CHEMBL1393116 Potency 631.0 nM
CCc1ccc(C2CC(=O)N3CN(c4ccccc4)CSC3=C2C#N)cc1 CHEMBL1542061 Potency 631.0 nM
CC(=O)Oc1cc2oc(=O)c3c(c2cc1Cl)CCC3 CHEMBL1564004 Potency 631.0 nM
O=C(O)c1cccc(S(=O)(=O)Nc2ccc3oc(=O)sc3c2)c1 CHEMBL1487744 Potency 631.0 nM
COc1ccc2c(c1)cc1n2CCN2CCCN=C12 CHEMBL1497727 Potency 631.0 nM
COc1ccc2ccccc2c1C(O)c1nccn1C CHEMBL1345866 Potency 631.0 nM
COc1cc(OC)c(C2CC(=O)N3CN(c4ccccc4C)CSC3=C2C#N)cc1OC CHEMBL1431174 Potency 631.0 nM
O=C(Cc1ccc(F)cc1)OCC(=O)c1cc2ccccc2o1 CHEMBL1327815 Potency 631.0 nM
CN(C)C(=O)/N=N\C(=O)N(C)C CHEMBL1359513 Potency 631.0 nM
CCOc1ccccc1N1CSC2=C(C#N)C(c3c(OC)ccc4ccccc34)CC(=O)N2C1 CHEMBL1319476 Potency 631.0 nM
Cc1ccc(-n2c(N)c(C(=O)N3CCN(C)CC3)sc2=S)cc1 CHEMBL1605172 Potency 631.0 nM
CSCCC(NC(C)=O)C(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCC3 CHEMBL1598952 Potency 631.0 nM
O=C(Nc1cccc(Cl)c1)N(CCCN1CCOCC1)Cc1ccccc1F CHEMBL1300686 Potency 631.0 nM
COc1cccc(CCc2ccccc2OCC[C@@H]2C[C@@H](O)CN2C)c1 CHEMBL1415927 Potency 631.0 nM
Oc1nc(-c2ccncc2)nc2ccccc12 CHEMBL1492428 Potency 631.0 nM
Oc1cc(O)c2c(c1)O[C@@H](c1ccc(O)c(O)c1)[C@H](O[C@@]1(c3cc(O)c(O)c(O)c3)Oc3cc(O)cc(O)c3[C@H](O)[C@@H]1O)C2 CHEMBL1604063 Potency 631.0 nM
NS(=O)(=O)c1cccc2c1c([N+](=O)[O-])cc1nc(O)c(O)nc12 CHEMBL222519 Potency 631.0 nM
COCc1cc(C)c(C#N)c(S)n1 CHEMBL1465117 Potency 631.0 nM
O=Nc1ccc2oc(=O)ccc2c1 CHEMBL1255659 Potency 631.0 nM
Oc1cc2c(cc1O)CN(C(=S)NCCc1ccc(Cl)cc1)CCC2 CHEMBL391997 Potency 631.0 nM
COc1ccc(CCNC(=O)CSc2nc(N)c(C#N)c(-c3cccs3)c2C#N)cc1OC CHEMBL1433027 Potency 631.0 nM
Cc1cc(C)n2nc(C(=O)NCc3ccccc3)cc2n1 CHEMBL1589593 Potency 631.0 nM
Oc1cc2c(cc1O)[C@H]1c3ccccc3CN[C@@H]1CC2 CHEMBL25856 Potency 631.0 nM
COCc1n[nH]c2c1C(c1cc(OC)c(O)c(OC)c1)C(C#N)=C(N)O2 CHEMBL1499248 Potency 631.0 nM
Oc1cccc(O)c1O CHEMBL307145 Potency 631.0 nM
COc1ccc(-c2ccc(-c3noc(-c4cccs4)n3)c(OC)n2)cc1 CHEMBL1606800 Potency 631.0 nM
O=C1/C(=N/CCc2cc(Br)c(O)c(Br)c2)C=C(O)c2cccnc21 CHEMBL336095 Potency 631.0 nM
O=C(c1cccs1)c1no[n+]([O-])c1C(=O)c1cccs1 CHEMBL570345 Potency 631.0 nM
Cc1cccc(-n2c(N)c(C(=O)N3CCN(C)CC3)sc2=S)c1 CHEMBL1505246 Potency 631.0 nM
CCOc1ccccc1N1C(=O)NC(=O)/C(=C\NCc2ccc3c(c2)OCO3)C1=O CHEMBL1465876 Potency 631.0 nM
CC(C)n1c(S)nc2c1c(=O)[nH]c(=O)n2C CHEMBL1479059 Potency 631.0 nM
COc1ccc(N2CSC3=C(C#N)C(c4cccs4)CC(=O)N3C2)cc1 CHEMBL1427447 Potency 631.0 nM
COc1ccc(-c2nc(S(=O)(=O)c3ccc(C)cc3)c(N3CCCC3)o2)cc1 CHEMBL1332732 Potency 631.0 nM
COc1ncc2nc(-c3cccs3)c(=O)n(-c3ccccc3)c2n1 CHEMBL1395026 Potency 631.0 nM
CCCCCCCCn1sccc1=O CHEMBL1562104 Potency 631.0 nM
COc1ccc2ccccc2c1C1CC(=O)N2CN(C)CSC2=C1C#N CHEMBL1427752 Potency 631.0 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(OC[C@H]3O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]3O)c(O)cc(O)c12 CHEMBL1551943 Potency 631.0 nM
COc1cc(/N=c2\ssnc2Cl)cc(OC)c1OC CHEMBL75913 Potency 631.0 nM
C=C(C)Cn1c(N2CCN(CC)CC2)nc2c1c(=O)[nH]c(=O)n2C CHEMBL1578893 Potency 631.0 nM
c1cncc(-c2nn3c(Cn4cnc5ccccc54)nnc3s2)c1 CHEMBL1492631 Potency 631.0 nM
O=C1CCCCCN1Sc1ccccc1 CHEMBL1480902 Potency 631.0 nM
Oc1ccc(Cc2nccc3cc(O)c(O)cc23)cc1O CHEMBL351585 Potency 631.0 nM
CCN1CCN(CCCNC(=O)c2cc3cc4ccc(OC)cc4nc3o2)CC1 CHEMBL1335319 Potency 631.0 nM
O=C(O)CCc1c2ccc(=O)c(O)c-2oc2c(O)c(O)ccc12 CHEMBL1481974 Potency 631.0 nM
COc1ccc(N2CCN(C(=O)CC(NC(N)=O)c3cccc(Oc4ccccc4)c3)CC2)cc1 CHEMBL1327420 Potency 631.0 nM
NS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccc(O)c(Cl)c3)sc2c1 CHEMBL5405943 IC50 780.0 nM
O=P(Nc1nccs1)(c1ccccc1)c1nc2ccccc2s1 CHEMBL1410147 Potency 794.3 nM
CCC(=O)N(CCc1ccccc1C)Cc1cc2cc3c(cc2nc1O)OCO3 CHEMBL1447714 Potency 794.3 nM
Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)cc1 CHEMBL1577023 Potency 794.3 nM
O=C(O)/C=C\c1c2ccc(=O)c(O)c-2oc2c(O)c(O)ccc12 CHEMBL1487801 Potency 794.3 nM
O=C(NC1CCCC1)c1cnn2c(C(F)(F)F)cc(-c3ccc4c(c3)OCO4)nc12 CHEMBL1381946 Potency 794.3 nM
CCOc1c(C(N)=O)c(-c2ccccc2)c2c(O)nc3ccccc3n12 CHEMBL1578407 Potency 794.3 nM
CCOC(=O)c1ccc(-c2nnc(-c3ccc(Cl)cc3Cl)o2)cc1 CHEMBL1518906 Potency 794.3 nM
NCC[Se][Se]CCN CHEMBL1397218 Potency 794.3 nM
COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2ccc(OC)c(OC)c2)c(OC)c1 CHEMBL1414783 Potency 794.3 nM
O=C(O)c1c(Br)c(Br)c(Br)c(Br)c1C1c2ccc(O)cc2Oc2cc(O)ccc21 CHEMBL516616 Potency 794.3 nM
O=C1C=CC(=O)c2c(O)cccc21 CHEMBL43612 Potency 794.3 nM
O=c1c(-c2ccc(F)cc2)nc2cnc(N3CCOCC3)nc2n1-c1ccccc1 CHEMBL1376987 Potency 794.3 nM
CCC(c1nnnn1C(C)(C)CC)N(CCCO)Cc1cc2cccc(C)c2nc1O CHEMBL1544315 Potency 794.3 nM
O=C(Nc1cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])c1)Nc1cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])c1 CHEMBL1253351 Potency 794.3 nM
COC(=O)c1ccc(CCc2cc(O)ccc2O)cc1 CHEMBL1491288 Potency 794.3 nM
N#Cc1nc(-c2ccc(Cl)cc2)oc1NCCc1ccccn1 CHEMBL1583909 Potency 794.3 nM
CCn1c(SCC(=O)Nc2ccc(NC(=O)c3ccco3)c(OC)c2)nc2ccccc2c1=O CHEMBL1584299 Potency 794.3 nM
Cc1ccc(S(=O)(=O)c2cc3c(=O)n4ccccc4nc3n(CC3CCCO3)c2=N)cc1C CHEMBL1549610 Potency 794.3 nM
CCCSC1=N/C(=C\C=C\c2ccco2)C(=O)S1 CHEMBL1589300 Potency 794.3 nM
Cc1ccc(Cn2c(C)nc3c(c2=O)c2nc4ccccc4nc2n3Cc2ccco2)cc1 CHEMBL1438452 Potency 794.3 nM
CCn1c(CNc2ccc(OC)cc2)nnc1SCC(=O)c1ccc(OC)cc1 CHEMBL1328429 Potency 794.3 nM
CCOc1nc(-c2ccccc2)ccc1-c1noc(-c2ccc(OC)c(OC)c2)n1 CHEMBL1528456 Potency 794.3 nM
C[N+](C)(C)CCC(=O)c1cccc2ccccc12 CHEMBL1358898 Potency 794.3 nM
CN1CCc2cc(O)c(O)cc2[C@H](c2ccccc2)C1 CHEMBL1355486 Potency 794.3 nM
CC/C(=N\c1ccc(N)cc1)C1=C(O)C(C(=O)OC)C(C)(C)CC1=O CHEMBL2132953 Potency 794.3 nM
CN(C)/C=N/c1c(Br)cc(Br)c2nonc12 CHEMBL1712181 Potency 794.3 nM
Cc1ccc(C2C(C(=O)c3sc(C)nc3C)=C(O)C(=O)N2CCCN(C)C)o1 CHEMBL1587322 Potency 794.3 nM
O=c1cc(-c2ccccc2)oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c(O)c(O)c12 CHEMBL1397367 Potency 794.3 nM
CCNc1cc2oc(=O)c(CN3CCOCC3)c(C)c2cc1C CHEMBL1454587 Potency 794.3 nM
CN1CCCCc2c1nc1ccccc1c2O CHEMBL1311735 Potency 794.3 nM
N=C1Sc2ccccc2C2=NCCCN12 CHEMBL595227 Potency 794.3 nM
CCCCC#CC1C=CC(OC(C)=O)C(COC(C)=O)O1 CHEMBL1356748 Potency 794.3 nM
Cc1cc(-c2csc(N)n2)c(C)n1CCc1ccccc1 CHEMBL1380028 Potency 794.3 nM
Cc1ccc(C2=Nc3ccccc3S[C@@H](c3cccc([N+](=O)[O-])c3)C2)cc1 CHEMBL1516996 Potency 794.3 nM
COc1ccc(-c2ccc(-c3noc(-c4ccccc4)n3)c(OC)n2)cc1 CHEMBL1537267 Potency 794.3 nM
CCn1c(=N)c(S(=O)(=O)c2ccc(F)cc2)cc2c(=O)n3ccccc3nc21 CHEMBL1581512 Potency 794.3 nM
Cn1c(=O)c2c(nc(OC/C=C/c3ccccc3)n2C)n(C)c1=O CHEMBL1386074 Potency 794.3 nM
Nc1c(C(=O)N2CCCCC2)sc(=S)n1-c1ccccc1 CHEMBL1549452 Potency 794.3 nM
O=C(O)c1cccc(NC(=O)c2ccccc2)c1 CHEMBL1513568 Potency 794.3 nM
COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CO CHEMBL1324178 Potency 794.3 nM
CCn1cc(S(=O)(=O)CC(=O)Nc2ccc3c(c2)OCCO3)c2ccccc21 CHEMBL1582040 Potency 794.3 nM
NC(=O)SCC(=O)Nc1ccc2ncccc2c1 CHEMBL1318635 Potency 794.3 nM
Cc1onc(-c2ccccc2)c1C(=O)Nc1cccc2nsnc12 CHEMBL1565576 Potency 794.3 nM
N[C@@H](CO)C(=O)NNCc1ccc(O)c(O)c1O CHEMBL1486563 Potency 794.3 nM
Clc1ccccc1-c1nnc2sc(CCc3ccccc3)nn12 CHEMBL500430 Potency 794.3 nM
COC(=O)c1c(N)n(Cc2ccc(OC)cc2)c2nc3ccccc3nc12 CHEMBL1336838 Potency 794.3 nM
CCOC(=O)c1ccc(NC(O)=C2C(=O)NC(=O)NC2=O)cc1 CHEMBL1528901 Potency 794.3 nM
CNC[C@H](O)c1ccc(O)c(O)c1 CHEMBL679 Potency 794.3 nM
COc1cc2ccc(=O)oc2c(O)c1O CHEMBL54909 Potency 794.3 nM
O=C(O)[C@@H](O)[C@@H](O)[C@@H](O)[C@@H](O)c1nc2ccccc2s1 CHEMBL1396791 Potency 794.3 nM
CCNc1ncc2nc(-c3ccc(Cl)cc3)c(=O)n(C3CC3)c2n1 CHEMBL1376954 Potency 794.3 nM
Cn1c(=O)[nH]c(=O)c2c1nc(SCC(=O)O)n2CCc1ccccc1 CHEMBL1426439 Potency 794.3 nM
CC(=O)Nc1ccc(C(=O)Cn2nnc3ccccc3c2=O)cc1 CHEMBL1504992 Potency 794.3 nM
Cc1sc2ccccc2[n+]1CCC(=O)O CHEMBL1526828 Potency 794.3 nM
C=CCN1CCc2c(cc(O)c(O)c2Br)[C@H](c2ccccc2)C1 CHEMBL286424 Potency 794.3 nM
COc1cc(-c2[o+]c3cc(O)cc(O)c3cc2O)cc(O)c1O CHEMBL1358860 Potency 794.3 nM
CCOC(=O)c1c(N2C(=O)C3C4C=CC(O4)C3C2=O)sc2c1CCCC2 CHEMBL1332712 Potency 794.3 nM
CCOC(=O)c1c(-c2ccc(C)o2)csc1N CHEMBL1382202 Potency 794.3 nM
CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3[C@H](O)[C@@H]12 CHEMBL1607480 Potency 794.3 nM
O=c1[nH][nH]c(=S)c(=O)[nH]1 CHEMBL1451986 Potency 794.3 nM
COc1ccc(C2CC(=O)N3CN(c4ccc(C)c(Cl)c4)CSC3=C2C#N)cc1OC CHEMBL1347985 Potency 794.3 nM
CCNc1ncc2nc(-c3ccc(Cl)cc3)c(=O)n(C)c2n1 CHEMBL1495694 Potency 794.3 nM
Cc1cc2sc(C)[n+](CCCOS(=O)(=O)[O-])c2cc1C CHEMBL1972052 Potency 794.3 nM
C[C@@H]1[C@H]2C=C[C@@H]1[C@@H](c1c3ccc(=O)c(O)c-3oc3c(O)c(O)ccc13)[C@@H]2C(=O)O CHEMBL1361000 Potency 794.3 nM
NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1356607 Potency 794.3 nM
COc1cc(OC)c(C2CC(=O)N3CN(c4ccc(C)cc4)CSC3=C2C#N)cc1OC CHEMBL1417556 Potency 794.3 nM
Nc1ccccc1S[C@@H](C[N+](=O)[O-])c1ccc2c(c1)OCO2 CHEMBL1368572 Potency 794.3 nM
CN1CC[C@]2(C)c3cc(O)ccc3N(C)[C@@H]12 CHEMBL1373567 Potency 794.3 nM
O=C(CSc1nc2cc(S(=O)(=O)N3CCOCC3)ccc2[nH]1)N1CCOCC1 CHEMBL1302980 Potency 794.3 nM
Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c(C)c1 CHEMBL1456621 Potency 794.3 nM
c1ccc2nc(-c3nc4ccccc4o3)ccc2c1 CHEMBL1466997 Potency 794.3 nM
COC(=O)c1cccc(OCC(O)Cn2cnc3cc(C)c(C)cc32)c1 CHEMBL1496162 Potency 794.3 nM
Cc1cc2c(N)cccc2nn1 CHEMBL1523317 Potency 794.3 nM
C=CCNC(=O)c1cnc2n(c1=O)CCS2 CHEMBL1378266 Potency 794.3 nM
N#CC1=C(N)SC(N)=C(C#N)C1c1ccnc2ccccc12 CHEMBL1422535 Potency 794.3 nM
CC(C)(C)c1cc(C(=S)N2CCN(CCO)CC2)cc(C(C)(C)C)c1O CHEMBL1579143 Potency 794.3 nM
O=c1[nH]c2nc(S)nc(S)c2[nH]1 CHEMBL1416009 Potency 794.3 nM
Cc1ccc2c(CN3C(=O)NC4(CCCCC4)C3=O)cc(=O)oc2c1C CHEMBL1309212 Potency 794.3 nM
Cc1ccccc1NC(=O)CSC(N)=O CHEMBL236685 Potency 794.3 nM
CC(C)(C)OC(=O)NCCc1nnc(S(=O)(=O)Cc2ccc(Cl)cc2Cl)o1 CHEMBL259018 Potency 794.3 nM
CCC(C)NCC(=O)Nc1ccc(-c2nc3cc(NC(=O)CNC(C)CC)ccc3o2)cc1 CHEMBL1574540 Potency 794.3 nM
O=C(NCCN1CCOCC1)NC1(C(F)(F)F)Oc2ccc(Cl)cc2O1 CHEMBL1530090 Potency 794.3 nM
CCOC(=O)c1sc(NC(=O)CSc2n[nH]c(-c3ccccc3)n2)c(C#N)c1C CHEMBL1453299 Potency 794.3 nM
S=c1nc(-c2ccccc2)n(CCN2CCOCC2)c2c1CCCC2 CHEMBL1501861 Potency 794.3 nM
COc1cccc(-c2nn3c(-c4cccc(C)c4)nnc3s2)c1 CHEMBL1532177 Potency 794.3 nM
COc1cc(C2CC(=O)N3CN(c4ccccc4C)CSC3=C2C#N)cc(OC)c1OC CHEMBL1304351 Potency 794.3 nM
O=C(NC(=Nc1ccccc1)N1CCOCC1)Nc1ccccc1 CHEMBL1597856 Potency 794.3 nM
CCOC(=O)C1C(=O)NC(SCC(=O)Nc2nccs2)=C(C#N)C1c1ccccc1OCC CHEMBL1441612 Potency 794.3 nM
CNc1ccnc(-c2c(C)noc2C)n1 CHEMBL1395107 Potency 794.3 nM
CC(=O)N(c1ccc(C(C)C)cc1)C1C=CS(=O)(=O)C1 CHEMBL1580252 Potency 794.3 nM
COCCn1c(N2CCN(c3ccc(OC)cc3)CC2)nc2c1c(=O)n(C)c(=O)n2C CHEMBL1508323 Potency 794.3 nM
c1ccc2sc(SN3CCOCC3)nc2c1 CHEMBL1530581 Potency 794.3 nM
COc1cc(C(Nc2ccccn2)c2ccc3ccc(C)nc3c2O)cc(OC)c1O CHEMBL1468811 Potency 794.3 nM
N[C@@H]1CCc2cc(O)c(O)cc2C1 CHEMBL1160788 Potency 794.3 nM
CC(C)OCCCNC(=O)CCN1C(=O)COc2ccccc21 CHEMBL1304906 Potency 794.3 nM
CC(=O)C(C(C)=O)c1c(Cl)c(O)c(O)c2c(C(=O)c3ccccc3)coc12 CHEMBL1493396 Potency 794.3 nM
O=C1c2ccccc2-c2cc([N+](=O)[O-])c([N+](=O)[O-])cc21 CHEMBL512908 Potency 794.3 nM
CCN1C(=O)[C@@H]2[C@H]3C(=CC[C@@H]2C1=O)C1(OCCCO1)[C@H]1O[C@@H]1[C@H]3O CHEMBL1415053 Potency 794.3 nM
CCNc1ncc2nc(-c3ccccc3)c(=O)n(C)c2n1 CHEMBL1472705 Potency 794.3 nM
CC(=O)Nc1ccc2nc(NCCc3ccc(O)c(Cl)c3)sc2c1 CHEMBL5431963 IC50 930.0 nM
COC(=O)c1cc([C@H](Nc2nc3cc(F)ccc3s2)P(=O)(OC)OC)ccc1O CHEMBL4107959 Kd 954.0 nM