CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCC5(CC4)OCCO5)CC3)on2)cc1 CHEMBL3696216 Kd 0.043 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCC5(CC4)OCCO5)CC3)no2)cc1 CHEMBL2443026 Kd 0.057 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCC(F)(F)CC4)CC3)no2)cc1 CHEMBL3696222 Kd 0.057 nM
CN1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc(N(C)C)cc3)no2)CC1 CHEMBL3696217 Kd 0.066 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCC5(CC4)OCCCO5)CC3)no2)cc1 CHEMBL3696220 Kd 0.079 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCC5(CC4)OCC(C)(C)CO5)CC3)no2)cc1 CHEMBL3696218 Kd 0.08 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCCCC4)CC3)no2)cc1 CHEMBL2443025 Kd 0.09 nM
CN1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc(N(C)C)cc3)on2)CC1 CHEMBL2443138 Kd 0.12 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(CC4CCCCC4)CC3)no2)cc1 CHEMBL3696221 Kd 0.188 nM
COc1c(C)cnc(Cn2cc(C#CCC(C)(C)O)c3c(Cl)nc(N)nc32)c1C CHEMBL1230584 Ki 0.2 nM
CC(C)Nc1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C)CC3)no2)cc1 CHEMBL2443139 Kd 0.218 nM
CN1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc([N+](=O)[O-])cc3)no2)CC1 CHEMBL3696223 Kd 0.24 nM
Cc1cc(C)c2cc1C(=O)NCCCCCNC(=O)CCSc1cc-2nc(N)n1 CHEMBL1939381 Kd 0.25 nM
O=C(NC1CCN(C2CCCCC2)CC1)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 CHEMBL2443131 Kd 0.3 nM
C[C@H](CSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1)C(N)=O CHEMBL3104281 Kd 0.33 nM
CN1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc([N+](=O)[O-])cc3)on2)CC1 CHEMBL2443044 Kd 0.35 nM
Cc1cc(C)c2cc1C(=O)NCCCCNC(=O)CCSc1cc-2nc(N)n1 CHEMBL1939380 Kd 0.38 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N5CCOCC5=O)cc4)cc23)c1 CHEMBL3892221 KD 0.418 nM
CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(C(=O)NC3CCN(C4CCC5(CC4)OCCCCO5)CC3)no2)cc1 CHEMBL3696219 Kd 0.423 nM
CS(=O)(=O)NCCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104273 Kd 0.43 nM
NC(=O)OCCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104277 Kd 0.46 nM
NC(=O)CCCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104289 Kd 0.48 nM
Cc1cc(C)c2cc1C(=O)NCCCNC(=O)CCSc1cc-2nc(N)n1 CHEMBL1939379 Kd 0.52 nM
Nc1nc(SCCO)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104276 Kd 0.54 nM
CC(CSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1)C(N)=O CHEMBL3104280 Kd 0.6 nM
Cc1cc(C)c2cc1C(=O)NCCNC(=O)CCCSc1cc-2nc(N)n1 CHEMBL1939382 Kd 0.61 nM
Cc1cc(C)c2cc1C(=O)NCCCC(=O)NCCSc1cc-2nc(N)n1 CHEMBL1939383 Kd 0.65 nM
CNC(=O)CCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104285 Kd 0.66 nM
NC(=O)CCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104278 Kd 0.66 nM
Cc1cc(C)c2cc1C(=O)NCCOC(=O)NCCSc1cc-2nc(N)n1 CHEMBL1939384 Kd 0.7 nM
COc1c(C)cnc(Cn2cc(C#CCO)c3c(Cl)nc(N)nc32)c1C CHEMBL2205798 IC50 0.7 nM
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NCCCCNC(=O)Cc3ccc4c(c3)C(C)(C)C3=[N+]4CCC4OC5CCN6C(=C5C=C34)C(C)(C)c3cc(S(=O)(=O)[O-])ccc36)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O CHEMBL2419341 Kd(app) 0.7 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3cccc(Br)c3)nn1)C(=O)C2 CHEMBL4873718 IC50 0.71 nM
CN(Cc1ccco1)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2F)c(O)cc1O CHEMBL3943099 KD 0.721 nM
CO[C@H]1C[C@H](C)Cc2cc(ccc2O)NC(=O)/C(C)=C/CC[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]1O CHEMBL512489 Kd 0.8 nM
Cc1cc(C)c2cc1C(=O)NCCNC(=O)OCCSc1cc-2nc(N)n1 CHEMBL1939385 Kd 0.8 nM
CCNC(=O)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 CHEMBL2443029 Kd 0.8 nM
O=C(NC1CCN(C2CCC(F)(F)CC2)CC1)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 CHEMBL3696215 Kd 0.8 nM
CC(=O)NCCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104272 Kd 0.82 nM
C#Cc1cn(Cc2ncc(C)c(OC)c2C)c2nc(N)nc(Cl)c12 CHEMBL2205245 IC50 1.0 nM
C[C@@H]1C[C@H]2O[C@@H]2/C=C\C=C\C(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1 CHEMBL414883 Kd 1.2 nM
Cc1cc(C)c2cc1C(=O)NCCCOc1cccc(c1)Sc1cc-2nc(N)n1 CHEMBL1939374 Kd 1.3 nM
NC(=O)CSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104288 Kd 1.3 nM
Nc1nc(SCCC(=O)NCCO)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104287 Kd 1.3 nM
Nc1ncnc2c1nc(Sc1cc3c(cc1I)OCO3)n2CCCNC(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1 CHEMBL2419342 Kd(app) 1.4 nM
NC(=O)NCCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104274 Kd 1.4 nM
CN(C)CCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104275 Kd 1.5 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc(C(=O)NC(=N)N)cc1 CHEMBL4126250 Kd 1.5 nM
Cc1ccccc1-n1nccc1-c1cc(C(=O)N(C)Cc2ccco2)c(O)cc1O CHEMBL3906838 KD 1.56 nM
Nc1nc(SC[C@H]2CNC(=O)O2)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104284 Kd 1.6 nM
COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc32)c1C CHEMBL467399 Ki 1.7 nM
Nc1nc(SC[C@@H]2CNC(=O)O2)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104283 Kd 1.8 nM
COc1c(C)cnc(Cn2cc(C#CCCO)c3c(Cl)nc(N)nc32)c1C CHEMBL2205799 IC50 2.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL252164 Ki 2.0 nM
CO[C@H]1C[C@H](C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)/C(C)=C/C=C\[C@@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]1O)C2=O CHEMBL3104859 Ki 2.0 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N5CCN(C)CC5)cc4)cc23)c1 CHEMBL3889463 KD 2.289 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N5CCOCC5)cc4)cc23)c1 CHEMBL3937274 KD 2.396 nM
CO[C@H]1/C=C\C=C(/C)C(=O)Nc2ccc(O)c(c2)C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O CHEMBL511439 Kd 2.5 nM
CN(C)C(=O)CCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL3104286 Kd 2.5 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3ccccc3F)nn1)C(=O)C2 CHEMBL4854592 IC50 2.68 nM
CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CC[C@H](O)CC4)c3)c2C1 CHEMBL560895 IC50 3.0 nM
Cc1cn(-c2cc(F)c(C(N)=O)c(N[C@H]3CCOC3)c2)c2c1C(=O)CC(C)(C)C2 CHEMBL3104858 Ki 3.0 nM
Cc1cn(-c2cc3c(c(C4CCOCC4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235355 Ki 3.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NO)=N2)n1 CHEMBL3675264 IC50 3.0 nM
Cc1ccccc1CN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2C)c(O)cc1O CHEMBL3911424 KD 3.013 nM
CCCNC(=O)c1ccc(CN(C)C(=O)c2cc(C(C)C)c(O)cc2O)cc1 CHEMBL4289811 Kd 3.08 nM
CC(C)N1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc([N+](=O)[O-])cc3)on2)CC1 CHEMBL2443048 Kd 3.2 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3ccccc3Cl)nn1)C(=O)C2 CHEMBL4849823 IC50 3.28 nM
CCCc1n[nH]c2c(Br)c(O)c(C(=O)N(C)c3ccc(N4CCOCC4)cc3)cc12 CHEMBL3944325 KD 3.391 nM
CSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 CHEMBL1834096 Kd 3.4 nM
CSc1nc(N)nc(-c2ccc3c4c(cc(Cl)cc24)COC3)n1 CHEMBL1939369 Kd 3.4 nM
CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL252124 KD 3.46 nM
COc1ccccc1CN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2C)c(O)cc1O CHEMBL3920953 KD 3.797 nM
Cc1ccccc1-n1c(-c2cc(C(=O)N(C)Cc3cccs3)c(O)cc2O)n[nH]c1=O CHEMBL3907641 KD 3.807 nM
COc1c(C)cnc(Cn2cc(CCCO)c3c(Cl)nc(N)nc32)c1C CHEMBL2205800 IC50 3.9 nM
CC(C)N(CCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21)C(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1 CHEMBL1910764 Kd(app) 3.9 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOC[C@H](N)CO)=N2)n1 CHEMBL3675257 IC50 4.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCCCO)=N2)n1 CHEMBL3675267 IC50 4.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC(=O)N3CC[C@@H](F)C3)=N2)n1 CHEMBL3675270 IC50 4.0 nM
Cc1ccccc1-n1c(-c2cc(C(=O)N(C)Cc3ccccc3)c(O)cc2O)n[nH]c1=O CHEMBL3903964 KD 4.005 nM
COC(=O)c1ccccc1OCCCOc1ccc(C)cc1OC CHEMBL1407606 IC50 4.05 nM
Cc1cccc(CN(C)C(=O)c2cc(-c3n[nH]c(=O)n3-c3ccccc3C)c(O)cc2O)c1 CHEMBL3906699 KD 4.082 nM
CC(=O)N[C@@H](CSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1)C(N)=O CHEMBL3104279 Kd 4.4 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N5CCNCC5)cc4)cc23)c1 CHEMBL3901758 KD 4.586 nM
C=CCNC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL109480 Ki 4.6 nM
CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3c(ccn3C)c2)c(O)cc1O CHEMBL2103879 IC50 5.0 nM
Cc1cn(-c2cc3c(c(C4CCCC4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235353 Ki 5.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOC3C[C@@H](O)[C@@H](O)C3)=N2)n1 CHEMBL3675262 IC50 5.0 nM
O=c1[nH]c2cc(CNS(=O)(=O)c3cccnc3)ccc2n1-c1cc(Cl)c(O)cc1O CHEMBL4544701 IC50 5.0 nM
COc1c(O)cc2cc1C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)CC/C=C(\C)C(=O)N2 CHEMBL267792 IC50 5.0 nM
CCCc1n[nH]c2cc(O)c(C(=O)N(C)c3ccc(C4CCN(C)CC4)cc3)cc12 CHEMBL3934788 KD 5.103 nM
CO[C@H]1C[C@H](C)Cc2cccc(c2)NC(=O)/C(C)=C/CC[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]1O CHEMBL469932 Kd 5.4 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccccc4)cc23)c1 CHEMBL3896847 KD 5.426 nM
COc1cc(C)c2cc1C(=O)NCCCOc1cccc(c1)Sc1cc-2nc(N)n1 CHEMBL1939377 Kd 5.8 nM
CCC(C)c1n[nH]c2cc(O)c(C(=O)N(C)c3ccc(N4CCOCC4)cc3)cc12 CHEMBL3942566 KD 5.809 nM
CCCCN(C)C(=O)c1n[nH]c2cc(O)c(C(=O)N(C)c3ccc(N4CCOCC4)cc3)cc12 CHEMBL3906698 KD 5.957 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)n1)CN(C(=O)NC13CC(C1)C3)C2 CHEMBL1774924 Ki 6.0 nM
COc1c(C)cnc(Cn2cc(-c3ccccc3)c3c(Cl)nc(N)nc32)c1C CHEMBL2205244 IC50 6.0 nM
Cc1cn(-c2cc3c(c(C4CCCCC4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235354 Ki 6.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC[C@H](C)CO)=N2)n1 CHEMBL3675259 IC50 6.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCCCCO)=N2)n1 CHEMBL3675268 IC50 6.0 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc5c(c4)OCO5)cc23)c1 CHEMBL3966607 KD 6.163 nM
Cc1cc(C)c2cc1C(=O)NCCCCCOc1cccc(c1)Sc1cc-2nc(N)n1 CHEMBL1939376 Kd 6.2 nM
CCOc1ccc(-c2snnc2-c2cc(Cl)c(O)cc2O)cc1 CHEMBL517583 Kd 6.3 nM
CCNC(=O)c1ccc(CN(C)C(=O)c2cc(C(C)C)c(O)cc2O)cc1 CHEMBL4279132 IC50 6.5 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNC2CCCCC2)cc1 CHEMBL3234778 IC50 6.8 nM
Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N(C)C)cc4)cc23)c1 CHEMBL3902156 KD 6.872 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)n1)CN(C(=O)NC1CCC1)C2 CHEMBL1738803 Ki 7.0 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCc3ccccc3)n1)CN(C(=O)NC1CCC1)C2 CHEMBL1774910 Ki 7.0 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)n1)CN(C(=O)NC1CCC1)C2 CHEMBL1774918 Ki 7.0 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)n1)CN(C(=O)NCC(F)(F)F)C2 CHEMBL1774926 Ki 7.0 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3cccc(Cl)c3)nn1)C(=O)C2 CHEMBL4857130 IC50 7.38 nM
Cc1cc(C)c2cc1C(=O)NCCCCOc1cccc(c1)Sc1cc-2nc(N)n1 CHEMBL1939375 Kd 7.4 nM
CC(C)NCCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21 CHEMBL200102 KD 7.62 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3ccccc3C#N)nn1)C(=O)C2 CHEMBL4853099 IC50 7.99 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC3C[C@@H](O)[C@@H](O)C3)=N2)n1 CHEMBL3675263 IC50 8.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC(=O)N(C)C)=N2)n1 CHEMBL3675269 IC50 8.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NO[C@@H](CCO)C(=O)N(C)C)=N2)n1 CHEMBL3675271 IC50 8.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC(=O)N(C)CCO)=N2)n1 CHEMBL3675273 IC50 8.0 nM
COc1cc(Cl)c(-c2nc(SCC(=O)N(C)C)nc3[nH]cc(C#N)c23)cc1OC CHEMBL2158562 IC50 8.0 nM
COc1c(O)cc2cc1C[C@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)C[C@H](OC(N)=O)[C@@H](OC)CC/C=C(\C)C(=O)N2 CHEMBL4557781 IC50 8.319 nM
COc1c(C)cnc(Cn2cc(C#CCCNC(=O)CN3CCN(c4ccc(Nc5ncc6c(C)c(C(C)=O)c(=O)n(C7CCCC7)c6n5)nc4)CC3)c3c(Cl)nc(N)nc32)c1C CHEMBL5414597 Kd 8.39 nM
CCCCN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2F)c(O)cc1O CHEMBL3945793 KD 8.723 nM
CCCCN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2)c(O)cc1O CHEMBL3954287 KD 8.801 nM
Cc1ccc(N(C)C(=O)c2cc3c(Cc4cccc(C)c4)n[nH]c3cc2O)cc1 CHEMBL3899564 KD 8.895 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)n1)CN(C(=O)NC1CC(F)(F)C1)C2 CHEMBL1774923 Ki 9.0 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)n1)CN(C(=O)NCC(F)F)C2 CHEMBL1774925 Ki 9.0 nM
COc1cc(Cl)c(-c2nc(SCC(=O)NCC(F)(F)F)nc3[nH]cc(C#N)c23)cc1O CHEMBL5406955 IC50 9.0 nM
CCNC(=O)c1cc(-c2c(O)cc(O)cc2Oc2ccc(Cl)cc2)on1 CHEMBL2443028 Kd 9.2 nM
CCOc1cc(C)c2cc1C(=O)NCCCOc1cccc(c1)Sc1cc-2nc(N)n1 CHEMBL1939378 Kd 10.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCCCC2CCO)cc1 CHEMBL3234771 IC50 10.0 nM
Cc1cn(-c2cc3c(c(-c4ccc(F)cc4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235361 Ki 10.0 nM
COc1cncc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360312 IC50 10.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOC[C@H]3COCCO3)=N2)n1 CHEMBL3675260 IC50 10.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC3O[C@@H](OC)[C@H](O)[C@@H]3O)=N2)n1 CHEMBL3675261 IC50 10.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC3CCC(O)CC3)=N2)n1 CHEMBL3962788 IC50 10.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCCC[C@H](O)CO)=N2)n1 CHEMBL3675266 IC50 10.0 nM
CCNC(=O)c1n[nH]c(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL365617 KD 10.7 nM
Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3cc(F)c(F)cc3Cc3nnn[nH]3)ccc2n1 CHEMBL3889584 KD 10.97 nM
CC(F)(F)CNC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)c2C1 CHEMBL1738805 Ki 11.0 nM
Nc1nc2cc(n1)-c1cc(c(Cl)cc1Cl)OCCCCOc1cccc(c1)S2 CHEMBL1939373 Kd 11.0 nM
Cc1cnc(Cn2ccc3c(Cl)nc(N)nc32)c(C)c1Cl CHEMBL3898024 KD 11.02 nM
CNC(=O)c1ccc(CN(C)C(=O)c2cc(C(C)C)c(O)cc2O)cc1 CHEMBL4293186 IC50 11.4 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)n1)CN(C(=O)NC1CC1)C2 CHEMBL1774922 Ki 12.0 nM
O=C(O[C@H]1[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2[C@@]2(CO)O[C@@H]12)c1ccc(O)cc1 CHEMBL2332354 Kd 12.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNCCCN(CC)CC)cc1 CHEMBL3235110 IC50 12.0 nM
COc1cccc(-c2cc(C)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360306 IC50 12.0 nM
COCc1n[nH]c2cc(O)c(C(=O)N(C)c3ccc(N4CCOCC4)cc3)cc12 CHEMBL3899246 KD 12.01 nM
COc1ccc(-c2snnc2-c2cc(Cl)c(O)cc2O)cc1 CHEMBL454733 Kd 13.0 nM
CCNC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)c2C1 CHEMBL1774921 Ki 13.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CC[C@H](N(C)C)C2)cc1 CHEMBL3234777 IC50 13.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360305 IC50 13.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC(CO)CO)=N2)n1 CHEMBL3675258 IC50 13.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOCC(=O)N(C)C[C@H](O)CO)=N2)n1 CHEMBL3675272 IC50 13.0 nM
CC(C)c1cc(C(=O)N2Cc3ccc(CN4CCN(C)CC4)cc3C2)c(O)cc1O CHEMBL1214827 IC50 13.0 nM
COC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL278315 IC50 13.0 nM
CCCN(C)S(=O)(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2F)c(O)cc1O CHEMBL3943106 KD 13.9 nM
O=C(O[C@H]1[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2[C@@]2(CO)O[C@@H]12)[C@H]1[C@H](C(=O)O[C@H]2[C@@H]3C=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]3[C@@]3(CO)O[C@@H]23)[C@@H](c2ccc(O)cc2)[C@@H]1c1ccc(O)cc1 CHEMBL2332352 Kd 14.0 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NC5CCCC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235335 Ki 14.0 nM
Cc1cn(-c2cc3c(c(-c4ccccc4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235360 Ki 14.0 nM
COC(=O)[C@H](NC(=O)COCCOCCOCCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1)C(C)C CHEMBL4072042 IC50 14.0 nM
O=c1[nH]nc(-c2cc(CCc3ccccc3)c(O)cc2O)n1-c1ccccc1F CHEMBL3940468 KD 14.35 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNCCN2CCOCC2)cc1 CHEMBL3235108 IC50 14.8 nM
O=C1OCC/C=C/CC/C=C/C(=N/OCC(=O)N2CCCCC2)Cc2cc(O)cc(O)c21 CHEMBL564698 GI50 15.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNCCN(CC)CC)cc1 CHEMBL3235109 IC50 15.0 nM
CC1=C2C[C@]3(C)C(=O)C[C@@H](C(C)(C)O)[C@H]3C/C=C(/C)[C@@H]2CC1=O CHEMBL4447639 Kd 15.3 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCN3CC(F)(F)C3)n1)CN(C(=O)NC1CCC1)C2 CHEMBL1774916 Ki 16.0 nM
O=C(O[C@H]1[C@@H]2CCO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2[C@@]2(CO)O[C@@H]12)c1ccc(O)cc1 CHEMBL2332365 Kd 16.0 nM
COc1nc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)cnc1C CHEMBL3360313 IC50 16.0 nM
COc1ccc([C@H]2Cc3nc(N)nc(C)c3C(=O)N2)c(-c2cccc(OC)n2)c1 CHEMBL3360307 IC50 16.0 nM
COCCOc1nc2c(c(N(C)C)n1)CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4779990 IC50 16.0 nM
C#CCN(C)CCCOc1ccc(N(CC)C(=O)c2cc(C(C)C)c(O)cc2O)cc1Cl CHEMBL5426666 IC50 16.0 nM
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C=C(C2=O)[C@H](OC)[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O CHEMBL486827 IC50 16.82 nM
Cc1ccc(-c2snnc2-c2cc(Cl)c(O)cc2O)cc1 CHEMBL457042 Kd 17.0 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NCC5CC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235336 Ki 17.0 nM
CC(C)c1cc(-n2nnc(C(=O)NCCCl)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL3235112 IC50 17.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCCCC3)cc2)c(O)cc1O CHEMBL3342721 IC50 17.0 nM
CNc1nc(OCCOC)nc2c1CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4782374 IC50 17.0 nM
O=c1[nH]nc(-c2cc(Br)c(O)cc2O)n1-c1ccccc1F CHEMBL3898029 KD 17.79 nM
C[C@@H]1C/C=C/CC/C=C/C(=N/OCC(=O)N2CCCCC2)Cc2cc(O)cc(O)c2C(=O)O1 CHEMBL556911 GI50 18.0 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)n1)CN(C(=O)NC1CC1)C2 CHEMBL1774908 Ki 18.0 nM
C/C=C(\C)C(=O)O[C@@H]1/C=C\[C@]2(O)C3=CC(=O)O[C@@H](c4ccoc4)[C@]3(C)CC[C@]2(O)[C@]2(C)C(=O)C[C@@]1(C)[C@@H]2CC(=O)OC CHEMBL4850751 Kd 18.2 nM
COc1c(C)cnc(Cn2cc(C#CCCn3cc(C(=O)NCCOCCOCNC(=O)CN4CCN(c5ccc(Nc6ncc7c(C)c(C(C)=O)c(=O)n(C8CCCC8)c7n6)nc5)CC4)nn3)c3c(Cl)nc(N)nc32)c1C CHEMBL5414252 Kd 18.7 nM
CN(C(=O)c1cc2c(C(=O)N3CCCC3)n[nH]c2cc1O)c1ccc(N2CCOCC2)cc1 CHEMBL3970784 KD 18.73 nM
COc1cccc(-c2ccccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360304 IC50 19.0 nM
COCCOc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4797602 IC50 19.0 nM
COCCOc1nc2c(c(NC3CC3)n1)CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4753741 IC50 19.0 nM
C#CCN(C)CCCOc1ccc(N(C)C(=O)c2cc(C(C)C)c(O)cc2O)cc1Cl CHEMBL5423568 IC50 19.0 nM
C#CCCCn1c(Sc2cc3c(cc2Br)OCO3)nc2c(N)ncnc21 CHEMBL365159 EC50 20.0 nM
CNC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)c2C1 CHEMBL1774920 Ki 20.0 nM
Cc1cn(-c2cc3c(c(CC(C)C)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235352 Ki 20.0 nM
Cc1cn(-c2cc3c(c(-c4cccc(F)c4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235362 Ki 20.0 nM
C/C1=C/C[C@@H]2[C@H](C(C)C)CC(=O)[C@@]2(C)/C=C2/C(C)CCC12 CHEMBL4530479 Kd 20.5 nM
O=C(CCCCCn1c(=O)[nH]c2ccccc2c1=O)Nc1ccc(Br)cc1F CHEMBL5282185 Kd 20.8 nM
COc1ccc(NCC(=O)Nc2ncc(Cc3ccc(Cl)c(Cl)c3)s2)cc1 CHEMBL5282664 Kd 20.9 nM
O=C1OCC/C=C/CC/C=C/C(=N/OCC(=O)N2CCCCC2)Cc2c(Cl)c(O)cc(O)c21 CHEMBL564932 GI50 21.0 nM
CC(C)NC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)c2C1 CHEMBL1774907 Ki 21.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 CHEMBL3234768 IC50 21.0 nM
O=C(c1cc(Nc2ccccc2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL3260492 IC50 21.0 nM
CCN(CC)Cc1ccc(-c2c(-c3cc(C(C)C)c(O)cc3O)noc2NC(=O)C2CC2)cc1 CHEMBL3342722 IC50 21.0 nM
CNC(=O)[C@H](NC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1)C(C)C CHEMBL4093385 IC50 21.0 nM
Cc1ccccc1-n1c(-c2cc(C(=O)N(C)CC3CCCO3)c(O)cc2O)n[nH]c1=O CHEMBL3914091 KD 21.05 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3ccc(C#N)cc3)nn1)C(=O)C2 CHEMBL4858125 IC50 21.77 nM
CCCNc1cc(-n2c3c(c4c2CC(C)(C)CC4=O)CCN(C)C3)ccc1C(N)=O CHEMBL3235339 Ki 22.0 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NCC(C)(C)C)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235344 Ki 22.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCCC(O)C2)cc1 CHEMBL3234765 IC50 23.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCC[C@H](O)C2)cc1 CHEMBL3234767 IC50 23.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(Cn2ccnc2)cc1 CHEMBL3234770 IC50 23.0 nM
COc1ccc(-c2c(-c3cc(C(C)C)c(O)cc3O)noc2NC(=O)C2CC2)cc1 CHEMBL3342597 IC50 23.0 nM
Cc1c(C(=O)Nc2ccc(SC#N)cc2)nnn1-c1ccc(C(C)C)cc1 CHEMBL5201663 IC50 23.0 nM
CCCN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2F)c(O)cc1O CHEMBL3908022 KD 23.61 nM
Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3ccccc3CO)ccc2n1 CHEMBL3979513 KD 23.84 nM
COc1nc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)cnc1N CHEMBL3360314 IC50 24.0 nM
COC(=O)c1ccc(CN(C)C(=O)c2cc(C(C)C)c(O)cc2O)cc1 CHEMBL5175785 IC50 24.0 nM
CC(=O)O[C@H]1C[C@@]2(C)[C@H](c3ccoc3)OC(=O)[C@H]3O[C@]32[C@]2(C)[C@H](O)C[C@H]3C(C)(C)O[C@H]4CC(=O)OC[C@]43[C@@H]12 CHEMBL4865803 Kd 24.8 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN(CC)CC)cc1 CHEMBL3234772 IC50 25.0 nM
CC(C)Nc1cc(-n2c3c(c4c2CC(C)(C)CC4=O)CCN(C)C3)ccc1C(N)=O CHEMBL3235343 Ki 25.0 nM
O=C(c1cc(Br)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4168598 Kd(app) 25.0 nM
CC(=O)O[C@H]1C[C@@]2(C)[C@H](c3ccoc3)OC(=O)[C@H]3O[C@]32[C@@]2(C)[C@H]1[C@@]1(C)C=CC(=O)OC(C)(C)[C@@H]1C[C@H]2OC(C)=O CHEMBL4869402 Kd 25.3 nM
COC(=O)[C@@H](OC(C)=O)[C@H]1C(C)(C)[C@H](O)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CC[C@@H]3[C@@]1(C)C2=O CHEMBL4870060 Kd 25.5 nM
CCNC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)c2C1 CHEMBL1774905 Ki 26.0 nM
O=C(/C=C/c1ccc(O)cc1)O[C@H]1[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2[C@@]2(CO)O[C@@H]12 CHEMBL2332355 Kd 26.0 nM
O=C(c1cc(Sc2ccccc2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4160774 Kd(app) 26.0 nM
Cc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4781723 IC50 26.0 nM
CCOc1nc(OCCOC)nc2c1CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4793342 IC50 26.0 nM
CCc1cc(-c2n[nH]c(C)c2-c2ccccc2F)c(O)cc1O CHEMBL3970310 KD 26.06 nM
Nc1nc2c(c(-c3c(Cl)cc(Cl)cc3OCCc3ccccn3)n1)CN(C(=O)NC1CCC1)C2 CHEMBL1774911 Ki 27.0 nM
O=c1[nH]c2cc(CNS(=O)(=O)c3ccccc3)ccc2n1-c1cc(Cl)c(O)cc1O CHEMBL1801577 IC50 27.0 nM
CC(C)c1cc(-n2nncc2-c2ccc(CN3CCN(Cc4ccccc4)CC3)cc2)c(O)cc1O CHEMBL3234761 IC50 27.0 nM
CC(C)c1cc(-n2nnc(C(=O)NC3CCCC3)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL3235114 IC50 27.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL3342720 IC50 27.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCN(C)CC3)cc2)c(O)cc1O CHEMBL3342723 IC50 27.0 nM
COc1nc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)cs1 CHEMBL3360317 IC50 27.0 nM
CCCN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2C)c(O)cc1O CHEMBL3958803 KD 27.73 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NC5CCSCC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235338 Ki 28.0 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NCC(F)F)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235341 Ki 28.0 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NCC5(C)COC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235342 Ki 28.0 nM
CC(C)NCCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)nccc21 CHEMBL3426784 IC50 28.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCN1CCS(=O)(=O)CC1 CHEMBL3600503 IC50 28.0 nM
CCNC(=O)[C@H](NC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1)C(C)C CHEMBL4073419 IC50 28.0 nM
CC1=C2C[C@]3(C)CC[C@@H](C(C)C)[C@H]3C/C=C(/C)[C@@H]2CC1=O CHEMBL4522895 Kd 28.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OCCN4CCOCC4)ncc3C2)c(O)cc1O CHEMBL4759029 IC50 28.0 nM
CCNc1nc(OCCOC)nc2c1CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4797252 IC50 28.0 nM
CCNC(=O)c1noc2c1CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL3233488 IC50 29.0 nM
CC1CN(Cc2ccc(-c3c(-c4cc(C(C)C)c(O)cc4O)noc3NC(=O)C3CC3)cc2)CC(C)O1 CHEMBL3342728 IC50 29.0 nM
O=C(c1cc(Sc2cc(Cl)cc(Cl)c2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4169566 Kd(app) 29.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OCCN4CCCC4)ncc3C2)c(O)cc1O CHEMBL4746663 IC50 29.0 nM
C#CCCCn1c(Sc2cc(OC)ccc2I)nc2c(N)ncnc21 CHEMBL191635 EC50 30.0 nM
Oc1cc(O)c(-c2noc3ccc(NCCN4CCOCC4)cc23)cc1Cl CHEMBL404630 IC50 30.0 nM
O=c1[nH]c2cc(CNS(=O)(=O)c3cccc4ccccc34)ccc2n1-c1cc(Cl)c(O)cc1O CHEMBL1801578 IC50 30.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCC[C@@H](O)C2)cc1 CHEMBL3234766 IC50 30.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCC(N4CCOCC4)CC3)cc2)c(O)cc1O CHEMBL3342735 IC50 30.0 nM
CO[C@H]1C[C@H](C)Cc2cc(cc(O)c2O)NC(=O)/C(C)=C/CC[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]1O CHEMBL401784 IC50 30.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OCCN(C)C)ncc3C2)c(O)cc1O CHEMBL4744192 IC50 30.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OCCN4CCCCC4)ncc3C2)c(O)cc1O CHEMBL4751556 IC50 30.0 nM
COCCOc1nc2c(c(OC)n1)CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4753836 IC50 30.0 nM
COCCOc1nc2c(c(NC(C)C)n1)CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4753338 IC50 30.0 nM
O=C(O[C@@H]1C[C@@](O)(CO)[C@H]2[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C[C@H]21)c1ccc(O)cc1 CHEMBL2332346 Kd 31.0 nM
CC(C)c1cc(-n2nnc(C(=O)NCCCCCCC(=O)NO)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL3235118 IC50 31.0 nM
Cc1ccc(C)c(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 CHEMBL4177418 Kd(app) 31.0 nM
CN1CCc2c3c(n(-c4cc(F)c(C(N)=O)c(N[C@H]5CCOC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235333 Ki 32.0 nM
CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNC2CCN(C)CC2)cc1 CHEMBL3235111 IC50 32.0 nM
CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1C CHEMBL4060353 Ki 32.0 nM
CCN(CC)CCOc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4777147 IC50 32.0 nM
CCCNc1nc(OCCOC)nc2c1CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4755251 IC50 32.0 nM
CCNC(=O)C1(c2ccc3nc(N)nc(C(=O)N4Cc5ccccc5C4)c3c2)CCC1 CHEMBL3962733 KD 32.85 nM
O=c1[nH]nc(-c2ccc(O)cc2O)n1-c1ccccc1Cl CHEMBL3909055 KD 32.95 nM
CCNC(=O)NCc1ccc2c(c1)[nH]c(=O)n2-c1cc(Cl)c(O)cc1O CHEMBL1801575 IC50 33.0 nM
CN(C)c1cc2c(cc1Sc1nc3c(N)nccc3n1CCNCC(C)(C)C)OCO2 CHEMBL2419346 IC50 33.0 nM
C/C=C(\C)C(=O)O[C@H]1C[C@@H](O)[C@@]2(C)CO[C@H]3[C@H]4O[C@@H]5C[C@@H](c6ccoc6)C(C)=C5[C@@]4(C)[C@H](CC(=O)OC)[C@]1(C)[C@@H]32 CHEMBL2270444 Kd 33.0 nM
CCCCCCCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL3235113 IC50 33.0 nM
CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NCCCCCCC(=O)NO)c3C2)c(O)cc1O CHEMBL3233755 IC50 33.0 nM
Cc1c2c(n3c1CCN(CC(C)C)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O CHEMBL3401151 Ki 33.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC1CC1 CHEMBL3600499 IC50 33.0 nM
COc1ccc(-c2snnc2-c2cc(Cl)c(O)cc2O)cc1OC CHEMBL515048 Kd 34.0 nM
Cc1cn(-c2cc3c(c(C4CCC4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235356 Ki 34.0 nM
CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NCCCl)c3C2)c(O)cc1O CHEMBL3233754 IC50 34.0 nM
CN(c1ccccc1)c1ccc(O)c(C(=O)N2Cc3ccccc3C2)c1 CHEMBL4165495 Kd(app) 34.0 nM
CC(O)(C#CCc1ccccc1)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O CHEMBL5276395 IC50 34.0 nM
CC1(C)[C@H]2CC[C@]1(C)N(Cc1cn(-c3ccccc3)nn1)C(=O)C2 CHEMBL4864906 IC50 34.01 nM
Cc1ccccc1-n1c(-c2cc(C(=O)N(C)Cc3ccccc3-c3cccnc3)c(O)cc2O)n[nH]c1=O CHEMBL3954162 KD 34.57 nM
CCc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 CHEMBL3661115 Ki 34.7 nM
CCc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4ccnn4C)c3)ccnc21 CHEMBL5218680 Ki 34.7 nM
COc1ccc(CN(C)C(=O)c2cc(-c3n[nH]c(=O)n3-c3ccccc3C)c(O)cc2O)cc1 CHEMBL3899438 KD 34.83 nM
NC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCn3cccn3)c2C1 CHEMBL1774919 Ki 35.0 nM
CC(C)c1cc(-n2nncc2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL3234762 IC50 35.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)CC(C)C)cc1 CHEMBL3342586 IC50 35.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN(C(C)C)C(C)C)cc2)c(O)cc1O CHEMBL3342725 IC50 35.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCCCC3C)cc2)c(O)cc1O CHEMBL3342730 IC50 35.0 nM
CCCc1cc(-c2n[nH]cc2-c2ccc3c(c2)OCCO3)c(O)cc1O CHEMBL3956397 KD 35.07 nM
CC(C)c1cc(-n2nncc2-c2ccc(CN3CCN(c4ccccc4)CC3)cc2)c(O)cc1O CHEMBL3234760 IC50 36.0 nM
CC1(C)CC(=O)c2c3c(n(-c4ccc(C(N)=O)c(N[C@H]5CCOC5)c4)c2C1)CCCC3 CHEMBL3235351 Ki 36.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCc4ccccc4C3)cc2)c(O)cc1O CHEMBL3342727 IC50 36.0 nM
COc1c(C)cnc(Cn2cc(Cc3ccccc3)c3c(Cl)nc(N)nc32)c1C CHEMBL3891745 IC50 36.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OCCCN(C)C)ncc3C2)c(O)cc1O CHEMBL4789546 IC50 36.0 nM
CCCOc1nc(OCCOC)nc2c1CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4778049 IC50 36.0 nM
CC(C)c1cc(-n2nncc2-c2ccc(CN3CCCC(O)C3)cc2)c(O)cc1O CHEMBL3234763 IC50 37.0 nM
CC(C)Nc1cc(-n2c3c(c4c2CC(C)(C)CC4=O)CCN(C)C3)cc2c1C(=O)NCC2 CHEMBL3235345 Ki 37.0 nM
CCC(=O)Nc1onc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL3342582 IC50 37.0 nM
COc1cccc(-c2ccc(F)cc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360308 IC50 37.0 nM
COc1cccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 CHEMBL4175693 Kd(app) 37.0 nM
N#CCCNC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)c2C1 CHEMBL1774906 Ki 38.0 nM
O=C(c1cc(-n2ccc3ccccc32)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL3260480 IC50 38.0 nM
Cc1ccc2c(ccn2-c2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 CHEMBL3260491 IC50 38.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C(C)C)cc1 CHEMBL3342584 IC50 38.0 nM
CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CC[C@H](OC(=O)CN)CC4)c3)c2C1 CHEMBL1195136 IC50 38.0 nM
Cc1ncc2c(n1)CN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4744238 IC50 38.0 nM
CCCCOCc1ncnc2sc3c(c12)CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC3 CHEMBL5273021 IC50 38.0 nM
CNC(=O)c1[nH]nc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL424811 IC50 39.0 nM
O=C(c1cc(-n2ccc3c([N+](=O)[O-])cccc32)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL3260487 IC50 39.0 nM
CC(C)c1cc(-c2onc(C(=O)N[C@@H](C(=O)N3CC(F)(F)C3)C(C)C)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL4096929 IC50 39.0 nM
Oc1cc(O)c(-c2noc3ccc(NCCN4CCOCC4)cc23)cc1Br CHEMBL254875 IC50 40.0 nM
N#CCCCOc1cc(Cl)cc(Cl)c1-c1nc(N)nc2c1CN(C(=O)NC1CCC1)C2 CHEMBL1774912 Ki 40.0 nM
CC(=O)NCc1ccc2c(c1)[nH]c(=O)n2-c1cc(Cl)c(O)cc1O CHEMBL1801572 IC50 40.0 nM
Cc1ccc2cc1-c1cc(nc(N)n1)Sc1cccc(c1)OCCCCO2 CHEMBL1939371 Kd 40.0 nM
COc1ccc(-c2cc(-n3cc(C)c4c3CC(C)(C)CC4=O)cc3c2C(=O)NCC3)cc1 CHEMBL3235363 Ki 40.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NC(=O)c1cccnc1 CHEMBL3600795 IC50 40.0 nM
Cc1ccc(Cc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)cc1 CHEMBL4162694 Kd(app) 40.0 nM
COc1ccc(NC(=O)CN2CCN(Cc3ccc4c(c3)CN(C(=O)c3cc(C(C)C)c(O)cc3O)C4)CC2)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4167999 IC50 40.0 nM
CCc1ccccc1-n1c(-c2ccc(O)cc2O)n[nH]c1=O CHEMBL3911783 KD 40.16 nM
CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCCCCC(=O)NO)ccc32)c(O)cc1O CHEMBL4237454 IC50 40.2 nM
CC(C)(CSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1)C(N)=O CHEMBL3104282 Kd 41.0 nM
Cc1c2c(n3c1CCN(Cc1ccoc1)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O CHEMBL3401155 Ki 41.0 nM
CCOC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(S(C)(=O)=O)cc1 CHEMBL4648197 IC50 41.8 nM
CCOc1ccc(-c2snnc2-c2cc(CC)c(O)cc2O)cc1 CHEMBL514748 Kd 42.0 nM
CCSc1nc(C)nc(N)n1 CHEMBL1834390 Kd 42.0 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(N[C@H]5CCOC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235334 Ki 42.0 nM
CC(C)Cc1cc(-n2c3c(c4c2CC(C)(C)CC4=O)CCN(C)C3)cc2c1C(=O)NCC2 CHEMBL3235350 Ki 42.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C(C)(C)C)cc1 CHEMBL3342585 IC50 42.0 nM
CCc1cc(-c2noc(NC(C)=O)c2-c2ccc(OC)cc2)c(O)cc1O CHEMBL3342595 IC50 42.0 nM
CCNC(=O)c1cc2c(-c3cc(OCCN(CC)CC)c(Cl)cc3Cl)nc(N)nc2s1 CHEMBL549749 Ki 42.0 nM
CCCCCCCC(=O)Nc1onc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL3342587 IC50 43.0 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1cccc(S(C)(=O)=O)c1 CHEMBL4647171 IC50 43.12 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(S(C)(=O)=O)cc1 CHEMBL4639163 IC50 43.27 nM
CC(C)c1cc(C(=O)N2Cc3ccc(NC(=O)CCCCCC(=O)NO)cc3C2)c(O)cc1O CHEMBL4798549 IC50 43.9 nM
CC(C)c1cc(C(=O)N2Cc3ccc(NC(=O)CCCCCCC(=O)NO)cc3C2)c(O)cc1O CHEMBL4790559 IC50 43.9 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C2CCCC2)cc1 CHEMBL3342590 IC50 44.0 nM
COc1ccc(-c2c(-c3cc(Br)c(O)cc3O)noc2NC(C)=O)cc1 CHEMBL3342593 IC50 44.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCC(N4CCCC4)CC3)cc2)c(O)cc1O CHEMBL3342734 IC50 44.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CN1CCN(C(=O)c2ccc(C(F)(F)F)nc2)CC1 CHEMBL3600506 IC50 45.0 nM
CC(C)NC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#Cc1ccccc1 CHEMBL3600494 IC50 45.0 nM
CC(C)[C@@H]1CC(=O)[C@@]2(C)/C=C3\C(CC[C@@]3(C)O)[C@]3(C)O[C@@H]3CC12 CHEMBL4570119 Kd 45.0 nM
COCC#CC(C)(O)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O CHEMBL5280465 IC50 45.0 nM
CC(C)c1cc(-c2nnn(Cc3ccccc3)c2-c2ccc(S(C)(=O)=O)cc2)c(O)cc1O CHEMBL4641526 IC50 45.7 nM
CN1CCc2c3c(n(-c4ccc(C(N)=O)c(NC5CC5)c4)c2C1)CC(C)(C)CC3=O CHEMBL3235340 Ki 46.0 nM
CC1CC(C)CN(Cc2ccc(-c3c(-c4cc(C(C)C)c(O)cc4O)noc3NC(=O)C3CC3)cc2)C1 CHEMBL3342729 IC50 46.0 nM
CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCCCCCC(=O)NO)ccc32)c(O)cc1O CHEMBL4241615 IC50 46.3 nM
CC(C)c1cc(C(=O)N2Cc3ccc(NC(=O)CCCCCCCCC(=O)NO)cc3C2)c(O)cc1O CHEMBL4789155 IC50 46.8 nM
O=c1[nH]c2cc(CNS(=O)(=O)c3ccc4ccccc4c3)ccc2n1-c1cc(Cl)c(O)cc1O CHEMBL1801579 IC50 47.0 nM
COc1ccc(NC(=O)CNC(=O)CN2CCN(Cc3ccc4c(c3)CN(C(=O)c3cc(C(C)C)c(O)cc3O)C4)CC2)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4175858 IC50 47.0 nM
CCN(CC)CCOc1cc(-c2nc(N)nc3sc(C(=O)NCC(F)(F)F)cc23)c(Cl)cc1Cl CHEMBL560099 IC50 47.0 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc2c(c1)OCCO2 CHEMBL4635982 IC50 47.85 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCN1CCC(=NOC)CC1 CHEMBL3600501 IC50 48.0 nM
COc1c(C)cnc(Cn2cc(Cc3ccc(Cl)cc3)c3c(Cl)nc(N)nc32)c1C CHEMBL3940517 IC50 48.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-c4cccnc4)c3)c12 CHEMBL4555835 IC50 48.0 nM
CC(=O)O[C@H]1C[C@@H](OC(C)=O)[C@@]2(C)CO[C@@H]3[C@@H](O)[C@@]4(C)C5=CC[C@@H](c6ccoc6)[C@]5(C)CC[C@@H]4[C@]1(C)[C@@H]32 CHEMBL463701 Kd 49.0 nM
CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCC(=O)NO)ccc32)c(O)cc1O CHEMBL4249195 IC50 49.3 nM
CCCCCCN(C)C(=O)c1cc(-c2ccnn2-c2ccccc2C)c(O)cc1O CHEMBL3912563 KD 49.54 nM
CO[C@H]1C[C@H](C)Cc2cc(cc(Cl)c2O)NC(=O)/C(C)=C/CC[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]1O CHEMBL511618 Kd 50.0 nM
Cc1cc(-c2c(Cl)cc(Cl)cc2OCCCC(F)(F)F)nc(N)n1 CHEMBL1774835 Ki 50.0 nM
CS(=O)(=O)NCc1ccc2c(c1)[nH]c(=O)n2-c1cc(Cl)c(O)cc1O CHEMBL1801574 IC50 50.0 nM
O=C(O[C@H]1[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2[C@@]2(CO)O[C@@H]12)[C@H]1[C@H](c2ccc(O)cc2)[C@H](C(=O)O[C@H]2[C@@H]3C=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]3[C@@]3(CO)O[C@@H]23)[C@H]1c1ccc(O)cc1 CHEMBL2332353 Kd 50.0 nM
Cc1c2c(n3c1CCN(CC#N)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O CHEMBL3401156 Ki 50.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NC(C)=O CHEMBL3600513 IC50 50.0 nM
CC(C)c1cc(C(=O)N2CCc3sccc3C2)c(O)cc1O CHEMBL3935883 IC50 50.3 nM
COc1c(C)cnc(Cn2cc(Cc3cccc(C)c3)c3c(Cl)nc(N)nc32)c1C CHEMBL3910684 IC50 51.0 nM
O=C(c1cc(Sc2ccc(O)cc2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4165074 Kd(app) 52.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-n4ccnc4)c3)c12 CHEMBL4575226 IC50 52.0 nM
CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCCCCCCC(=O)NO)ccc32)c(O)cc1O CHEMBL4247905 IC50 52.1 nM
COc1ccc([C@H]2c3cccc(c3O)NC(=O)/C(C)=C/C=C\[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@@H](O)[C@@H](OC)C[C@@H]2C)cc1 CHEMBL4474732 IC50 52.97 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)n[nH]c2C(N)=O)cc1 CHEMBL366215 IC50 53.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2N)cc1 CHEMBL3342580 IC50 53.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C2CC2)cc1 CHEMBL3342588 IC50 53.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN(C)CC(F)(F)F)cc1 CHEMBL5420862 IC50 53.0 nM
CCOC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1cccc(S(C)(=O)=O)c1 CHEMBL4635778 IC50 53.1 nM
CN1CCC(c2ccc(N(C)C(=O)c3cc4c(CCC(C)(C)C)n[nH]c4cc3O)cc2)CC1 CHEMBL3909490 KD 53.85 nM
O=c1[nH]c2ccccc2n1-c1cc(Cl)c(O)cc1O CHEMBL1802337 IC50 54.0 nM
CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NCCN4CCOCC4)c3C2)c(O)cc1O CHEMBL3233752 IC50 54.0 nM
C#CCN1CCc2c(C)c3c(n2-c2cc(Cl)c(C(N)=O)cc21)CC(C)(C)CC3=O CHEMBL3401152 Ki 54.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC1CCCC1 CHEMBL3600498 IC50 54.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-c4cnn(C)c4)c3)c12 CHEMBL4531254 IC50 54.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN(C)CCN(C)C)cc2)c(O)cc1O CHEMBL3342732 IC50 55.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-c4ccncc4)c3)c12 CHEMBL4587186 IC50 55.0 nM
CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCCC(=O)NO)ccc32)c(O)cc1O CHEMBL4241177 IC50 55.9 nM
CCCCc1cc(-n2cc(C)c3c2CC(C)(C)CC3=O)cc2c1C(=O)NCC2 CHEMBL3235357 Ki 56.0 nM
CCOc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360310 IC50 56.0 nM
CCOc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4763114 IC50 56.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OC4CCOCC4)ncc3C2)c(O)cc1O CHEMBL4762517 IC50 56.0 nM
CC(C)c1cc(C(=O)N(C)Cc2ccc(C(=O)O)cc2)c(O)cc1O CHEMBL5177655 IC50 56.0 nM
CC(O)(CCCc1ccccn1)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O CHEMBL5277312 IC50 56.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCSCC3)cc2)c(O)cc1O CHEMBL3342724 IC50 57.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NC(=O)c1ccc(OC)nc1 CHEMBL3600798 IC50 57.0 nM
CC(O)(CCCc1ccncc1)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O CHEMBL5289895 IC50 57.0 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 CHEMBL4647894 IC50 57.05 nM
CC(=O)N1CCc2c(C)c3c(n2-c2ccc(C(N)=O)c(c2)N[C@@H](C)[C@H](C)C1)CC(C)(C)CC3=O CHEMBL1807797 IC50 58.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN(C)C3CCCCC3)cc2)c(O)cc1O CHEMBL3342733 IC50 58.0 nM
COc1c(C)cnc(Cn2cc(Cc3ccc(C)cc3)c3c(Cl)nc(N)nc32)c1C CHEMBL3929614 IC50 58.0 nM
CNc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 CHEMBL4561141 IC50 58.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 CHEMBL3656929 IC50 58.0 nM
COCCOc1nc2c(c(OC(C)C)n1)CN(C(=O)c1cc(C(C)C)c(O)cc1O)CC2 CHEMBL4800429 IC50 58.0 nM
CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCCCCCCCC(=O)NO)ccc32)c(O)cc1O CHEMBL4237899 IC50 58.6 nM
CCNC(=O)Nc1onc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL3342592 IC50 59.0 nM
Oc1cc(O)c(-c2ccnn2-c2ccccc2F)cc1I CHEMBL3960891 KD 59.62 nM
Oc1ccc2c(-c3cc(Cl)c(O)cc3O)noc2c1 CHEMBL362307 IC50 60.0 nM
O=C(NCc1ccc2c(c1)[nH]c(=O)n2-c1cc(Cl)c(O)cc1O)Nc1ccccc1 CHEMBL1801576 IC50 60.0 nM
Cc1c2c(n3c1CCN(C(=O)C(C)(C)N)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807807 IC50 60.0 nM
CCCC(=O)Nc1onc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL3342583 IC50 60.0 nM
Cc1c2c(n3c1CC(C)Oc1cc(C(N)=O)ccc1-3)CC(C)(C)CC2=O CHEMBL3403718 Ki 60.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-n3cnc(-c4cn[nH]c4)c3)c12 CHEMBL3661110 IC50 60.0 nM
NC(=O)c1ccc(-c2nccc3c(-c4cncc(N)c4)cccc23)cc1NC1CCC(O)CC1 CHEMBL3653850 IC50 60.0 nM
CCc1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 CHEMBL3653931 IC50 60.0 nM
O=C(c1cc(Cc2ccc(Cl)cc2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4170618 Kd(app) 60.0 nM
COc1cc(OC)c(OC)cc1CC(=O)c1ccc2c(c1OC)C=CC(C)(C)O2 CHEMBL4513831 IC50 60.0 nM
CCCOc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4757080 IC50 60.0 nM
CCN(c1cc(-c2cccc(N(C)C(=O)c3cc(C(C)C)c(O)cc3O)c2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 CHEMBL5395240 IC50 60.1 nM
CCOC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc2c(c1)OCCO2 CHEMBL4641450 IC50 60.93 nM
Cc1c2c(n3c1CCCN1C[C@@H](F)C[C@@H]1CNc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1779539 IC50 61.0 nM
CC(C)c1cc(C(=O)N(C)Cc2ccc(C(=O)NO)cc2)c(O)cc1O CHEMBL5174143 IC50 61.0 nM
COc1ccc(-c2c(C)n[nH]c2-c2cc(Br)c(O)cc2O)cc1 CHEMBL364968 IC50 62.0 nM
COCCNc1cc(-n2c3c(c4c2CC(C)(C)CC4=O)CCN(C)C3)ccc1C(N)=O CHEMBL3235337 Ki 62.0 nM
CC(C)CN(C)C(=O)c1n[nH]c2cc(O)c(C(=O)N(C)c3ccc(N4CCOCC4)cc3)cc12 CHEMBL3961450 KD 62.7 nM
CC(C)(C)c1ccc(Cn2cc(-c3cc(O)c(O)c(O)c3)nn2)cc1 CHEMBL4741221 Kd 63.0 nM
CCN(C(=O)c1cc(C(C)C)c(O)cc1O)c1cccc(-c2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c(C)c(N(CC)C3CCOCC3)c2)c1 CHEMBL5408322 IC50 63.6 nM
Cc1c2c(n3c1CCNC[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807791 IC50 64.0 nM
Cc1c2c(n3c1CCN(C)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O CHEMBL3401148 Ki 64.0 nM
CC[C@H](N)C(=O)N1CCc2c(C)c3c(n2-c2ccc(C(N)=O)c(c2)N[C@@H](C)[C@H](C)C1)CC(C)(C)CC3=O CHEMBL1807805 IC50 65.0 nM
O=C(c1cc(Sc2ccccc2O)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4161657 Kd(app) 65.0 nM
CC(C)Oc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4786802 IC50 65.0 nM
CC(C)COc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4763426 IC50 65.0 nM
Cc1c2c(n3c1CCN(C(=O)CO)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807801 IC50 66.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NC(=O)c1ccc(F)nc1 CHEMBL3600800 IC50 66.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCNC(=O)c1ccc(C(F)(F)F)nc1 CHEMBL3600508 IC50 66.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCN1CCOCC1 CHEMBL3600500 IC50 66.0 nM
CC(C)c1cc(-c2onc(C(N)=O)c2C#CCN2CCOCC2)c(O)cc1O CHEMBL3600434 IC50 66.0 nM
O=C(c1cc(Cc2ccccc2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4173418 Kd(app) 66.0 nM
Cc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)cc1C CHEMBL4159747 Kd(app) 66.0 nM
CC(C)c1cc(C(=O)N2Cc3ccc(NCc4ccc(C(=O)NO)cc4)cc3C2)c(O)cc1O CHEMBL4782478 IC50 66.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2cccc(-c3cnc4ccccc4c3)c12 CHEMBL4570276 IC50 67.0 nM
COc1c(C)cnc(Cn2cc(C#CCCn3cc(C(=O)NCCNC(=O)CN4CCN(c5ccc(Nc6ncc7c(C)c(C(C)=O)c(=O)n(C8CCCC8)c7n6)nc5)CC4)nn3)c3c(Cl)nc(N)nc32)c1C CHEMBL5402082 Kd 67.5 nM
Cc1c2c(n3c1CCN(C(=O)[C@@H]1CCCN1)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807810 IC50 68.0 nM
CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NC4CCCC4)c3C2)c(O)cc1O CHEMBL3233753 IC50 68.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NC(=O)c1cnc2ccccc2c1 CHEMBL3600797 IC50 69.0 nM
CCNC(=O)c1[nH]nc(-c2cc(Br)c(O)cc2O)c1-c1ccc(OC)cc1 CHEMBL190182 IC50 70.0 nM
Cc1c2c(n3c1CCN(C(=O)[C@@H](N)C(C)C)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807806 IC50 70.0 nM
O=C(c1cc(-n2ccc3c(Br)cccc32)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL3260486 IC50 70.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(C)=O)cc1 CHEMBL3342581 IC50 70.0 nM
CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCC(N(C)C)CC3)cc2)c(O)cc1O CHEMBL3342731 IC50 70.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N(O)C3CCCCC3)c2)c2nccc(-n3cnc(-c4cnn(C)c4)c3)c12 CHEMBL3661105 IC50 70.0 nM
CCCc1cc(C(N)=O)ccc1-n1nc(C(F)(F)F)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 CHEMBL3661164 IC50 70.0 nM
COCCNc1cc(C(N)=O)ccc1-n1nc(C(F)(F)F)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 CHEMBL3661176 IC50 70.0 nM
NC(=O)c1ccc(-c2nccc3c(-c4cnc5nc[nH]c5c4)cccc23)cc1NC1CCC(O)CC1 CHEMBL3653859 IC50 70.0 nM
Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(NC6CCC(O)CC6)c5)nccc34)cn2)cn1 CHEMBL3653880 IC50 70.0 nM
NC(=O)c1ccc(-c2nc(C(F)(F)F)nc3c(-c4cnc5ccccc5c4)cccc23)cc1NC1CCC(O)CC1 CHEMBL3653941 IC50 70.0 nM
Cc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c(C)c1 CHEMBL4170382 Kd(app) 70.0 nM
CCc1c2c(nc3ccc(O)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@@]3(CC)OC(=O)CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL4436271 IC50 70.0 nM
Cc1ccc(Nc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)cc1 CHEMBL3260493 IC50 71.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OC4CCCC4)ncc3C2)c(O)cc1O CHEMBL4797741 IC50 71.0 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(OCCN(C)C)cc1 CHEMBL4648091 IC50 71.16 nM
Cc1ccccc1-n1c(-c2cc(C(=O)N(C)Cc3cccc(-c4cncnc4)c3)c(O)cc2O)n[nH]c1=O CHEMBL3951501 KD 71.34 nM
O=C(NCc1ccc2c(c1)[nH]c(=O)n2-c1cc(Cl)c(O)cc1O)c1ccccc1 CHEMBL1801573 IC50 72.0 nM
COC(=O)[C@@H](CO)NC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL4076195 IC50 72.0 nM
CCc1c2c(nc3ccc(O)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@@]3(CC)OC(=O)CNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL4460245 IC50 72.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2cncc(-c3cnc4ccccc4c3)c12 CHEMBL3656928 IC50 72.0 nM
O=C(/C=C\c1ccc(O)cc1)O[C@@H]1C[C@@](O)(CO)[C@H]2[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C[C@H]21 CHEMBL2332361 Kd 73.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-c4ccoc4)c3)c12 CHEMBL4513271 IC50 73.0 nM
Cc1c2c(n3c1CCN(C(=O)CN)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807799 IC50 74.0 nM
COc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4778735 IC50 75.0 nM
CC(C)c1cc(C(=O)N2CCc3nc(OC4CCN(C)CC4)ncc3C2)c(O)cc1O CHEMBL4746857 IC50 76.0 nM
Cc1c2c(n3c1CCCN(C(=O)CO)[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807800 IC50 77.0 nM
O=C(c1cc(Cc2ccc(F)cc2)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL4174059 Kd(app) 77.0 nM
CCOC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1cccc(NS(C)(=O)=O)c1 CHEMBL4649532 IC50 77.01 nM
Cc1c2c(n3c1CCCN1CCC[C@@H](C1)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1779547 IC50 78.0 nM
O=C(c1cc(-n2ccc3cc(Br)ccc32)c(O)cc1O)N1Cc2ccccc2C1 CHEMBL3260490 IC50 78.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NS(=O)(=O)c1ccc(C)cc1 CHEMBL3600512 IC50 78.0 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1cccc(NS(C)(=O)=O)c1 CHEMBL4638275 IC50 78.32 nM
COc1cc(Cc2cn(Cc3ncc(C)c(OC)c3C)c3nc(N)nc(Cl)c23)ccc1Br CHEMBL3922135 IC50 79.0 nM
COC(=O)[C@H](NC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1)C(C)C CHEMBL4105335 IC50 79.0 nM
Cc1c2c(n3c1CCN(C(=O)[C@@H]1C[C@H](F)CN1)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1806511 IC50 80.0 nM
NC(=O)c1ccc(-c2nccc3c(-n4cnc(-c5cccnc5)c4)cccc23)cc1NC1CCC(O)CC1 CHEMBL3653869 IC50 80.0 nM
COCCNc1cc(-c2nc(C)cc3c(-n4cnc(-c5cnn(C)c5)c4)cccc23)ccc1C(N)=O CHEMBL3653925 IC50 80.0 nM
CC(C)c1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 CHEMBL3653940 IC50 80.0 nM
Cn1cc(-c2cn(-c3cccc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3N)cn2)cn1 CHEMBL3958214 IC50 80.0 nM
CCC(F)c1n[nH]c2cc(O)c(C(=O)N(C)c3ccc(N4CCOCC4)cc3)cc12 CHEMBL3897124 KD 80.55 nM
Cc1c2c(n3c1CCCN(C(=O)CN)[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807798 IC50 81.0 nM
Cc1c2c(n3c1CCCNC(=O)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1778208 IC50 82.0 nM
Cc1c2c(n3c1CCCN[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807790 IC50 82.0 nM
COC1CCN(C(=O)c2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N5CCOCC5)cc4)cc23)C1 CHEMBL3916782 KD 82.33 nM
COCCC(=O)N1CCc2c(C)c3c(n2-c2ccc(C(N)=O)c(c2)N[C@@H](C)[C@H](C)C1)CC(C)(C)CC3=O CHEMBL1807803 IC50 83.0 nM
Cc1c2c(n3c1CCN(C(=O)[C@H](C)N)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807804 IC50 83.0 nM
Cc1c2c(n3c1CCN(C(=O)C1(N)CCCC1)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807809 IC50 83.0 nM
Cc1c2c(n3c1CCN(CCO)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807795 IC50 84.0 nM
Cc1ccc2cc1-c1cc(nc(N)n1)Sc1cccc(c1)OCCCCCO2 CHEMBL1939372 Kd 84.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCN(CC(=O)NCC(=O)Nc3ccc(OC)c(Nc4ncc(Cl)c(Nc5ccccc5S(=O)(=O)C(C)C)n4)c3)CC2)cc1 CHEMBL4169444 IC50 84.8 nM
CC(=O)N1CCCc2c(C)c3c(n2-c2ccc(C(N)=O)c(c2)N[C@@H](C)[C@@H]1C)CC(C)(C)CC3=O CHEMBL1807796 IC50 85.0 nM
CC(C)c1cc(C(=O)N2CCc3cc(NCc4ccc(C(=O)NO)cc4)ccc32)c(O)cc1O CHEMBL4245766 IC50 85.7 nM
Cc1c2c(n3c1CCOc1cc(C(N)=O)ccc1-3)CC(C)(C)CC2=O CHEMBL3403716 Ki 86.0 nM
Cc1c2c(n3c1CCN(CCC(C)C)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O CHEMBL3401153 Ki 86.0 nM
CC(O)(CCCc1cccnc1)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O CHEMBL5286973 IC50 86.0 nM
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NCCN(C)C)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O CHEMBL383824 Kd 87.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-c4ccsc4)c3)c12 CHEMBL4589294 IC50 87.0 nM
Cc1c2c(n3c1CCN(C)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807793 IC50 88.0 nM
COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C2CCC2)cc1 CHEMBL3342589 IC50 88.0 nM
CCCCOc1ncc2c(n1)CCN(C(=O)c1cc(C(C)C)c(O)cc1O)C2 CHEMBL4796810 IC50 88.0 nM
C#CCCCn1c(Sc2cc(OC)c(OC)c(OC)c2Cl)nc2c(N)nc(F)nc21 CHEMBL193282 EC50 90.0 nM
Cc1c2c(n3c1CC[C@@H](C)N[C@H](C)CNc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1760611 IC50 90.0 nM
CCCc1cn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 CHEMBL3656953 IC50 90.0 nM
COc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 CHEMBL3661136 IC50 90.0 nM
CCc1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-n3cnc(-c4cccnc4)c3)c2n1 CHEMBL3653948 IC50 90.0 nM
CC(C)c1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-n3cnc(-c4ccc[n+]([O-])c4)c3)c2n1 CHEMBL3653955 IC50 90.0 nM
CCc1cc(C(N)=O)ccc1-n1nc(C(F)(F)F)c2c(-n3cnc(-c4cnn(C)c4)c3)cccc21 CHEMBL3945420 IC50 90.0 nM
COc1ccc(CC(=O)c2ccc3c(c2OC)C=CC(C)(C)O3)cc1OC CHEMBL2177146 IC50 90.0 nM
COC(=O)Cn1nnc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL4636983 IC50 90.95 nM
Cc1c2c(n3c1CCN(C(=O)[C@@H](O)C(C)C)C[C@@H](C)[C@H](C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1807813 IC50 91.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCN1C[C@@H](C)O[C@@H](C)C1 CHEMBL3600502 IC50 91.0 nM
CC(C)c1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2nccc(-n3cnc(-c4cncnc4)c3)c12 CHEMBL4441171 IC50 91.0 nM
Cc1cn(-c2cc3c(c(Cc4ccccc4)c2)C(=O)NCC3)c2c1C(=O)CC(C)(C)C2 CHEMBL3235359 Ki 94.0 nM
COc1ccc(Cc2cn(Cc3ncc(C)c(OC)c3C)c3nc(N)nc(Cl)c23)cc1 CHEMBL3901656 IC50 94.0 nM
Cc1nn(-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)c2cccc(-c3cnc4ccccc4c3)c12 CHEMBL4513265 IC50 94.0 nM
CC(C)c1cc(-n2nnc(C(=O)NC3CCCCC3)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O CHEMBL3235115 IC50 95.0 nM
O=c1[nH]nc(-c2ccc(O)cc2O)n1-c1ccccc1F CHEMBL3895370 KD 95.6 nM
Cc1c2c(n3c1CCCN1CCC[C@@H]1CNc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1738705 IC50 96.0 nM
Cc1c2c(n3c1CCCN1CCOC[C@@H]1CNc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1779533 IC50 96.0 nM
Cc1c2c(n3c1CCCN1CCC[C@H]1CNc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O CHEMBL1779531 IC50 96.0 nM
COc1ccc(-c2cn(-c3ccnc4c3c(C(C)C)nn4-c3ccc(C(N)=O)c(N[C@H]4CC[C@H](O)CC4)c3)cn2)cc1 CHEMBL4450667 IC50 96.0 nM
Oc1ccc(-c2nocc2-c2ccccc2)c(O)c1 CHEMBL3964633 KD 96.83 nM
COc1c(C)cnc(Cn2ncc3c(Cl)nc(N)nc32)c1C CHEMBL4080323 IC50 97.0 nM
COc1ccc([C@H]2c3cccc(c3O)NC(=O)/C(C)=C/C=C\[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@@H](OC)[C@@H](OC)C[C@@H]2C)cc1 CHEMBL4455526 IC50 97.11 nM
Cc1ccccc1-n1c(-c2ccc(O)cc2O)n[nH]c1=O CHEMBL3889899 KD 97.27 nM
COc1c(C)cnc(Cn2ccc3c(Cl)nc(N)nc32)c1C CHEMBL2205243 EC50 98.0 nM
COC(=O)[C@H](NC(=O)CCCCCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1)C(C)C CHEMBL4074892 IC50 98.0 nM
Cc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 CHEMBL3661113 IC50 98.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NC(=O)C1CCCCC1 CHEMBL3600789 IC50 99.0 nM