NC(N)=NC(=O)N1CCc2c(F)ccc(-c3c(F)cc(F)cc3F)c2C1 CHEMBL3654198 Ki 0.68 nM
NC(N)=NC(=O)N1Cc2c(-c3c(F)cccc3F)ccc(F)c2C2(CC2)C1 CHEMBL3654206 Ki 0.75 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL282199 Ki 0.78 nM
NC(N)=NC(=O)N1Cc2c(-c3ccc(F)cc3F)ccc(F)c2C2(CC2)C1 CHEMBL3654212 Ki 0.85 nM
NC(N)=NC(=O)N1Cc2c(-c3c(F)cc(F)cc3F)ccc(F)c2C2(CC2)C1 CHEMBL3654208 Ki 0.88 nM
NC(N)=NC(=O)N1Cc2c(-c3ccccc3F)ccc(F)c2C2(CC2)C1 CHEMBL3654214 Ki 0.95 nM
CSc1ccc2c(c1)C(N1CCN(C)CC1)Cc1ccccc1S2 CHEMBL93240 Ki 1.0 nM
C/C(=N\OC(=O)Nc1ccccc1)c1cccc(-c2cccs2)c1 CHEMBL1210154 IC50 1.0 nM
NC(N)=NC(=O)N1CCc2c(Cl)ccc(-c3c(F)cc(F)cc3F)c2C1 CHEMBL3654197 Ki 1.1 nM
NC(N)=NC(=O)N1CCc2c(F)ccc(-c3c(F)cccc3F)c2C1 CHEMBL3654199 Ki 1.1 nM
NC(N)=NC(=O)c1ccc2c(Cl)cnc(-c3c(F)cccc3F)c2c1 CHEMBL3644535 Ki 1.2 nM
NC(N)=NC(=O)c1ccc2ncc(Cl)c(-c3ccc(F)cc3F)c2c1 CHEMBL3644525 Ki 1.3 nM
Cc1cnc(-c2c(F)cc(F)cc2F)c2cc(C(=O)N=C(N)N)ccc12 CHEMBL3644530 Ki 1.3 nM
NC(N)=NC(=O)N1Cc2c(-c3cc(F)c(F)cc3F)ccc(F)c2C2(CC2)C1 CHEMBL3654210 Ki 1.3 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3c(F)cccc3F)c2c1 CHEMBL3644528 Ki 1.4 nM
Clc1ccc(CNC[C@H]2CCn3ccnc3C2)c2ncccc12 CHEMBL5093295 Ki 1.5 nM
C[C@@H]1NC(N)=Nc2cccc(Cl)c21 CHEMBL404372 Ki 1.6 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3c(F)cccc3Cl)c2c1 CHEMBL3644527 Ki 1.6 nM
CC1CN(C(=O)N=C(N)N)Cc2c(-c3c(F)cccc3F)ccc(F)c21 CHEMBL3654207 Ki 1.6 nM
C[C@@H]1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c21 CHEMBL256694 Ki 1.8 nM
Cc1cnc(-c2ccccc2F)c2cc(C(=O)N=C(N)N)ccc12 CHEMBL3644540 Ki 1.8 nM
Cc1cnc(-c2c(F)cccc2F)c2cc(C(=O)N=C(N)N)ccc12 CHEMBL3644537 Ki 1.9 nM
NC(N)=NC(=O)N1CCc2c(F)ccc(-c3ncc(Cl)cc3Cl)c2C1 CHEMBL3654205 Ki 1.9 nM
CC1NC(N)=Nc2ccc(Cl)c(Cl)c21 CHEMBL273170 Ki 2.0 nM
NC(N)=NC(=O)c1ccc2c(Cl)cnc(-c3ccc(F)cc3F)c2c1 CHEMBL3644541 Ki 2.3 nM
Clc1ccc(CNCCc2cccnc2)c2ncccc12 CHEMBL5079273 Ki 2.4 nM
NC(N)=NC(=O)N1CCc2c(Cl)ccc(-c3c(F)cncc3F)c2C1 CHEMBL3654204 Ki 2.5 nM
NC(N)=NC(=O)N1CCc2c(Cl)ccc(-c3ccc(F)cc3F)c2C1 CHEMBL3654200 Ki 2.7 nM
NC(N)=NC(=O)N1Cc2c(C3CC3)ccc(F)c2C2(CC2)C1 CHEMBL3654209 Ki 2.7 nM
Oc1ccc2cccc(N3CCNCC3)c2c1 CHEMBL24462 Ki 3.0 nM
CC1NC(N)=Nc2cccc(Cl)c21 CHEMBL270177 pA2 3.02 nM
O=S1(=O)CCC[C@@H](CNCc2ccc(Cl)c3cccnc23)C1 CHEMBL5075486 Ki 3.1 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3ccccc3F)c2c1 CHEMBL3644533 Ki 3.3 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3ccccc3Cl)c2c1 CHEMBL3644534 Ki 3.4 nM
NC(N)=NC(=O)N1CCc2cccc(-c3cc(F)c(F)cc3F)c2C1 CHEMBL3654196 Ki 3.6 nM
Cc1nc2ccc(C(=O)N=C(N)N)cc2c(-c2c(F)cc(F)cc2F)c1C CHEMBL3644526 Ki 3.7 nM
NC(N)=NC(=O)N1CCc2c(F)ccc(-c3cc(F)c(F)cc3F)c2C1 CHEMBL3654211 Ki 3.7 nM
Cc1ccc(-c2ncc(F)cc2F)c2c1CCN(C(=O)N=C(N)N)C2 CHEMBL3654203 Ki 3.9 nM
CN1CC[C@H](CNCc2ccc(Cl)c3cccnc23)CC1=O CHEMBL5089996 Ki 4.0 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3ccc(F)cc3Cl)c2c1 CHEMBL3644529 Ki 4.1 nM
NC(N)=NC(=O)N1CCc2cccc(-c3ncc(F)cc3F)c2C1 CHEMBL3654213 Ki 4.2 nM
NC(N)=NC(=O)N1CCc2c(F)ccc(-c3ncc(Cl)cc3F)c2C1 CHEMBL3654195 Ki 4.3 nM
NC(N)=NC(=O)c1ccc2c(C(F)F)cnc(-c3c(F)cccc3F)c2c1 CHEMBL3644539 Ki 4.6 nM
COc1cc(Cl)c(C)c2c1N=C(N)NC2C CHEMBL401745 Ki 4.7 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3c(F)cncc3Cl)c2c1 CHEMBL3644536 Ki 4.7 nM
COc1ccccc1N1CCN(CCCCC(=O)n2c3ccccc3c3ccccc32)CC1 CHEMBL3763779 Ki 5.0 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cn2)cc1)C(=O)/C=C/c1ccccc1 CHEMBL361256 Log Ki 5.012 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3c(F)cncc3F)c2c1 CHEMBL3644531 Ki 5.3 nM
CC1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c21 CHEMBL429136 Ki 5.7 nM
NC(N)=NC(=O)c1ccc2c(F)cnc(-c3ncc(F)cc3Cl)c2c1 CHEMBL3644538 Ki 6.2 nM
COc1cccc2c1N=C(N)NC2C CHEMBL408152 Ki 6.3 nM
CNC1=Nc2ccc(Cl)c(Cl)c2C(C)N1 CHEMBL271298 Ki 6.3 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)CCC1CCCC1 CHEMBL191460 Log Ki 6.31 nM
CC1NC(NCC(F)F)=Nc2cccc(Cl)c21 CHEMBL404511 Log Ki 6.31 nM
CC1NC(N)=Nc2c(Cl)ccc(Cl)c21 CHEMBL272781 Ki 6.5 nM
NC(N)=NC(=O)N1Cc2c(-c3ccc(F)cc3F)ccc(Cl)c2C(F)C1 CHEMBL3654202 Ki 6.6 nM
O=C1C[C@H](CNCc2ccc(Cl)c3cccnc23)CN1C1CC1 CHEMBL5094012 Ki 6.7 nM
Clc1ccc(CNCC[C@@H]2CCOC2)c2ncccc12 CHEMBL5093969 Ki 6.7 nM
C[C@@H]1NC(NCC(F)F)=Nc2cccc(Cl)c21 CHEMBL541993 Ki 6.8 nM
NC(N)=NC(=O)N1CCc2c(F)ccc(-c3ncc(F)cc3F)c2C1 CHEMBL3654201 Ki 6.9 nM
COc1cccc(F)c1-c1ncc(F)c2ccc(C(=O)N=C(N)N)cc12 CHEMBL3644532 Ki 7.1 nM
CNC1=Nc2cccc(Cl)c2C(C)N1 CHEMBL269964 pA2 7.413 nM
NCCc1c[nH]c2ccc(C(N)=O)cc12 CHEMBL1256863 Ki 8.639 nM
CCN(CC)C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL263881 Ki 9.0 nM
CC(C)Oc1cccc2c1N=C(N)NC2C CHEMBL258075 Ki 10.0 nM
O=C(CCCNCc1ccc(Cl)c2cccnc12)NC1CC1 CHEMBL3459329 Ki 12.0 nM
CC(C)(C)c1ccc2c(c1)CN(C[C@@H](O)COC1CCOCC1)CC2 CHEMBL5092728 Ki 12.0 nM
Cc1cnn(C[C@H](C)NCc2cccc(OCc3ccccn3)c2)c1 CHEMBL5074821 Ki 12.0 nM
N#CC1(c2ccccc2)CCC(NCCc2nnc3ccccn23)CC1 CHEMBL5093652 Ki 12.0 nM
Cc1cnc(NCc2ccccc2-n2ccnc2)nc1N(C)C CHEMBL5087322 Ki 12.0 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cn2)cc1)C(=O)CCC1CCCC1 CHEMBL190382 Log Ki 12.59 nM
Cn1c2c(c3ccccc31)CN(CCCOc1ccc(F)cc1)CC2 CHEMBL96504 Ki 13.0 nM
C[C@@H]1C[C@@H](C)N1C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1 CHEMBL138989 Ki 13.0 nM
Cc1cc(-c2c(F)cc(F)cc2F)c2cc(C(=O)N=C(N)N)ccc2n1 CHEMBL3644524 Ki 13.0 nM
CN1C[C@H](C(=O)N[C@]2(C)O[C@@]3(O)[C@@H]4CCCN4C(=O)[C@H](Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL442 Ki 14.0 nM
C[C@@H]1C[C@H](C)N1C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1 CHEMBL137781 Ki 16.0 nM
NCCc1c[nH]c2ccc(C(N)=O)cc12 CHEMBL18840 Ki 20.0 nM
COc1c(Cl)ccc2c1C(C)NC(NCC(F)F)=N2 CHEMBL257744 Ki 22.2 nM
CC(C)Oc1cccc2c1N=C(NCC(F)F)NC2C CHEMBL446459 Ki 22.2 nM
COc1c(Cl)ccc2c1C(C)NC(N)=N2 CHEMBL258073 Ki 22.9 nM
CCC1NC(N)=Nc2ccccc21 CHEMBL270841 Ki 24.0 nM
O=C(CCC1CCCC1)N(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)CC1CCCCN1 CHEMBL185676 Log Ki 25.12 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)nc1)C(=O)/C=C/c1ccccc1 CHEMBL187621 Log Ki 25.12 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)/C=C/c1ccccc1 CHEMBL188486 Log Ki 25.12 nM
CNC1=Nc2c(OC(C)C)cccc2C(C)N1 CHEMBL402179 Ki 25.4 nM
CCC1NC(N)=Nc2ccc(Cl)c(Cl)c21 CHEMBL439240 Ki 26.5 nM
C[C@H]1C[C@H](C)N1C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1 CHEMBL343755 Ki 27.0 nM
COc1cccc2c1N=C(NCC(F)F)NC2C CHEMBL404248 Ki 28.2 nM
CN1C[C@H](C(=O)N[C@]2(C)O[C@@]3(O)[C@@H]4CCCN4C(=O)[C@H](Cc4ccccc4)N3C2=O)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL1200517 Ki 31.3 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)nc1)C(=O)CCC1CCCC1 CHEMBL189689 Log Ki 31.62 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccn3)cc2)cc1)C(=O)CCC1CCCC1 CHEMBL186849 Log Ki 31.62 nM
CC1NC(NCC(F)F)=Nc2c(Cl)ccc(Cl)c21 CHEMBL271253 Ki 33.4 nM
CC1NC(NCC2COc3ccccc3O2)=Nc2ccccc21 CHEMBL256693 Ki 37.0 nM
CC1NC(N)=Nc2ccccc21 CHEMBL541396 Ki 38.0 nM
c1ccc2c(N3CCNCC3)cccc2c1 CHEMBL277120 Ki 40.0 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL1256844 Ki 42.29 nM
NC1=Nc2ccc(Cl)c(Cl)c2CN1 CHEMBL1548 Ki 43.0 nM
O=C(/C=C/c1ccccc1)N(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)Cc1cccnc1 CHEMBL187928 Log Ki 50.12 nM
COc1cc(OC)c(C2NCCc3c2[nH]c2ccc(Cl)cc32)cc1OC CHEMBL5207529 Ki 69.5 nM
Cc1nn(C)c(C)c1-c1cccc2c1CC[C@H](N(C)C)C2 CHEMBL2164327 Ki 75.19 nM
c1ccc(-c2ccccc2N2CCNCC2)cc1 CHEMBL494675 Ki 76.0 nM
NCCc1c[nH]c2ccc(O)cc12 CHEMBL39 IC50 79.0 nM
CN(C)CCc1c[nH]c2ccc(N3CCN(Cc4ccccc4)S3(=O)=O)cc12 CHEMBL101138 Log IC50 79.43 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)C1CC1c1ccccc1 CHEMBL191583 Log Ki 79.43 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCOc3ccccc3)cc2)cc1)C(=O)CCC1CCCC1 CHEMBL363678 Log Ki 79.43 nM
CCC1NC(N)=Nc2cccc(Cl)c21 CHEMBL270176 Ki 84.4 nM
CC1NC(NCC(F)F)=Nc2ccccc21 CHEMBL272355 Ki 87.0 nM
N=C1NC(=O)/C(=C\c2c[nH]c3ccc(Br)cc23)N1 CHEMBL2442272 Ki 89.0 nM
CC1NC(NCC2COCCO2)=Nc2ccccc21 CHEMBL404365 Ki 96.0 nM
COc1cccc2c1N=C(N)NC2 CHEMBL552782 Ki 97.0 nM
NC1=Nc2cccc(Cl)c2CN1 CHEMBL401541 Ki 99.0 nM
NC1=Nc2cccc(Cl)c2CN1 CHEMBL556983 Ki 99.0 nM
CCn1c2c(c3ccccc31)CN(CCCOc1ccccc1)CC2 CHEMBL128099 Ki 100.0 nM
Cn1c2c(c3ccccc31)CN(CCCOc1ccccc1)CC2 CHEMBL128848 Ki 100.0 nM
COc1ccc2[nH]c3c(-c4cn(C)c5ccccc45)nccc3c2c1 CHEMBL5285512 Ki 100.0 nM
N=C1NC(=O)/C(=C\c2c[nH]c3ccccc23)N1 CHEMBL2442270 Ki 101.0 nM
Cc1nc2sccn2c(=O)c1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL267777 Ki 101.52 nM
CNC1=Nc2ccccc2C(C)N1 CHEMBL272517 Ki 103.0 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 106.0 nM
CN(C)S(=O)(=O)C1(CNCc2ccc(Cl)c3cccnc23)CC1 CHEMBL5078567 Ki 107.0 nM
Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C)C1 CHEMBL589390 Ki 107.43 nM
N=C1NC(=O)/C(=C\c2c[nH]c3c(Br)cccc23)N1 CHEMBL2442274 Ki 112.0 nM
CCCNCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5081379 Ki 120.0 nM
CC1NC(NC2CCC2)=Nc2ccccc21 CHEMBL402400 Ki 122.0 nM
N=C1NC(=O)/C(=C\c2c[nH]c3cccc(Br)c23)N1 CHEMBL2442271 Ki 123.0 nM
CC1NC(NCCC2CCCCC2)=Nc2ccccc21 CHEMBL257302 Ki 124.0 nM
CN(C)CCc1c[nH]c2ccc(CCN3CCNS3(=O)=O)cc12 CHEMBL103549 Log IC50 125.89 nM
CN(C)CCc1c[nH]c2ccc(CN3CCCN(C)S3(=O)=O)cc12 CHEMBL323334 Log IC50 125.89 nM
CCN1CCN(CCc2ccc3[nH]cc(CCN(C)C)c3c2)S1(=O)=O CHEMBL321963 Log IC50 125.89 nM
c1ccc(CCNCc2ccc(-c3ccc(CNC4CCN(Cc5ccccc5)CC4)cc3)cc2)cc1 CHEMBL189262 Log Ki 125.89 nM
Cc1cccc2c1CNC(N)=N2 CHEMBL537248 Ki 145.0 nM
CCCNC1=Nc2ccccc2C(C)N1 CHEMBL270658 Ki 153.0 nM
CC1NC(NC[C@H]2CCCO2)=Nc2ccccc21 CHEMBL403102 Ki 163.0 nM
COc1ccc2c(c1)c1c(n2C)CCN(CCCOc2ccc(F)cc2)C1 CHEMBL128185 Ki 165.0 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(Oc2ccc(Cl)cc2)CC1 CHEMBL538029 Ki 168.0 nM
Cn1c2c(c3ccccc31)CN(CCCC(=O)c1ccccc1)CC2 CHEMBL129476 Ki 168.0 nM
CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C CHEMBL278751 Ki 168.0 nM
Oc1ccc2[nH]c3c(-c4c[nH]c5ccccc45)nccc3c2c1 CHEMBL5268604 Ki 170.0 nM
c1ccc2c(-c3nccc4c3[nH]c3ccccc34)c[nH]c2c1 CHEMBL3309924 Ki 170.0 nM
Cn1c2c(c3ccccc31)CN(CCCCCc1ccccc1)CC2 CHEMBL125417 Ki 174.0 nM
CCOCCCNC1=Nc2ccccc2C(C)N1 CHEMBL256049 Ki 176.0 nM
COc1ccc(C2NCCc3c2[nH]c2ccc(Cl)cc32)c(O)c1 CHEMBL5170784 Ki 177.0 nM
O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1 CHEMBL2105760 Ki 177.79 nM
N#Cc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccccc3)CC2)cc1 CHEMBL522691 Ki 178.0 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(Oc2ccc(Cl)cc2)CC1 CHEMBL95104 Log Ki 181.97 nM
N=C1NC(=O)/C(=C\c2c[nH]c3cc(Br)ccc23)N1 CHEMBL2442273 Ki 184.0 nM
Cn1c2c(c3ccccc31)CN(C/C=C/CCc1ccccc1)CC2 CHEMBL446356 Ki 185.0 nM
CCCCNC1=Nc2ccccc2C(C)N1 CHEMBL402874 Ki 189.0 nM
Cn1c2c(c3ccccc31)CN(CCCOc1ccc(N)cc1)CC2 CHEMBL435814 Ki 190.0 nM
CCCCCNC(=N)N/N=C/c1c[nH]c2ccc(OC)cc12 CHEMBL76370 AC50 190.0 nM
CCNC1=Nc2ccccc2C(C)N1 CHEMBL537022 Ki 196.0 nM
CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12 CHEMBL103371 Log IC50 199.53 nM
CC(=O)Nc1ccc(CN2CCN(Cc3ccc4[nH]cc(CCN(C)C)c4c3)S2(=O)=O)cc1 CHEMBL103388 Log IC50 199.53 nM
c1ccc(CCNCc2ccc(-c3cccc(CNC4CCN(Cc5ccccc5)CC4)c3)cc2)cc1 CHEMBL187415 Log Ki 199.53 nM
O=C(c1ccc2c(c1)OCO2)N(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)Cc1cccnc1 CHEMBL99071 Log Ki 199.53 nM
CN1CCC2C(C1)c1cccc3c1N2c1ccccc1CS3 CHEMBL3217984 pKi 199.53 nM
CC[C@@](C)(CO)CNC(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL97518 Ki 200.0 nM
Cn1c2c(c3ccccc31)CN(CCCOc1ccc(Cl)cc1)CC2 CHEMBL126898 Ki 200.0 nM
Cn1c2c(c3ccccc31)CN(CCCOc1ccc(Cl)c(Cl)c1)CC2 CHEMBL126897 Ki 200.0 nM
CCCCCNC(=N)N/N=C/c1c[nH]c2ccc(OC)cc12 CHEMBL1516474 Ki 200.91 nM
Cn1c2c(c3ccccc31)CN(C/C=C\CCc1ccccc1)CC2 CHEMBL2111848 Ki 208.0 nM
CN(C)S(=O)(=O)CCNCc1ccc(Cl)c2cccnc12 CHEMBL5082151 Ki 208.0 nM
Cc1ccc(Sc2ccccc2N2CCNCC2)c(C)c1 CHEMBL2204360 Ki 220.0 nM
COc1ccccc1-c1cc(CN(C)C)ccc1Cl CHEMBL3931889 Ki 220.0 nM
Cn1c2c(c3cccc(Cl)c31)CN(CCCOc1ccc(F)cc1)CC2 CHEMBL126737 Ki 225.0 nM
NC1=NC2(CCCCC2)NC(Nc2cccc(Br)c2)=N1 CHEMBL3770342 Ki 227.0 nM
Cn1c(=O)cnn(CCCCN2CCN(c3cccc4ccc(O[11CH3])cc34)CC2)c1=O CHEMBL199824 Ki 228.6 nM
CN(C)S(=O)(=O)CCNCc1cccc2cccnc12 CHEMBL5090584 Ki 229.0 nM
COc1ccc(C2NCCc3c2[nH]c2ccc(F)cc32)c(O)c1 CHEMBL5204071 Ki 229.0 nM
CCN(CC)Cc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5071978 Ki 230.0 nM
CCCNCCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5093342 Ki 240.0 nM
CCCOCCNC1=Nc2ccccc2C(C)N1 CHEMBL256048 Ki 241.0 nM
Cn1c2c(c3ccccc31)CN(CCCOc1ccc([N+](=O)[O-])cc1)CC2 CHEMBL130585 Ki 250.0 nM
CN(C)CCc1c[nH]c2ccc(CN3CC(C)(C)NS3(=O)=O)cc12 CHEMBL320412 Log IC50 251.19 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)S(=O)(=O)/C=C/c1ccccc1 CHEMBL188440 Log Ki 251.19 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNC3Cc4ccccc4C3)cc2)cc1)C(=O)CCC1CCCC1 CHEMBL365422 Log Ki 251.19 nM
Cn1c2c(c3cc(Cl)ccc31)CN(CCCOc1ccc(F)cc1)CC2 CHEMBL338095 Ki 270.0 nM
CN(C)S(=O)(=O)CCNCc1ccc(F)c2cccnc12 CHEMBL5092524 Ki 271.0 nM
Cc1ccc2c(c1)N=C(N)NC2 CHEMBL536789 Ki 274.0 nM
CC1NC(NC2CCCCN(C)C2=O)=Nc2ccccc21 CHEMBL403103 Ki 279.0 nM
OCCOCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL896 AC50 280.0 nM
Cn1c2c(c3ccccc31)CN(CCCC(O)c1ccc(F)cc1)CC2 CHEMBL338696 Ki 285.0 nM
CCCN[C@@H]1CCc2c(C(=O)OC)cccc2[C@@H]1C CHEMBL161507 Ki 287.0 nM
O=C(CCCCN1CCN(c2ccccc2O)CC1)n1c2ccccc2c2ccccc21 CHEMBL3764133 Ki 337.0 nM
Cn1c2c(c3ccccc31)CN(CCC/C(=N/O)c1ccc(F)cc1)CC2 CHEMBL126138 Ki 340.0 nM
NC1=Nc2cc(Cl)ccc2CN1 CHEMBL538340 Ki 347.0 nM
COc1ccc(OCCCN2CCc3c(c4ccccc4n3C)C2)cc1 CHEMBL340646 Ki 350.0 nM
CS(=O)(=O)C1(CNCc2cccc3cccnc23)CC1 CHEMBL5077128 pEC50 354.81 nM
CCCCNCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5094680 Ki 360.0 nM
COc1ccccc1-c1cc(CCN(C)C)ccc1Cl CHEMBL5074190 Ki 380.0 nM
CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21 CHEMBL71 AC50 380.0 nM
CC1(C)N=C(N)N=C(Nc2cccc(Br)c2)N1 CHEMBL582877 Ki 389.0 nM
CC1NC(NCCF)=Nc2ccccc21 CHEMBL257450 Ki 397.0 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)Nc1ccccc1 CHEMBL187029 Log Ki 398.11 nM
Fc1ccc(OCCCN2CCc3ccccc3C2)cc1 CHEMBL126667 Ki 400.0 nM
C[C@H]1NC(N)=Nc2cccc(Cl)c21 CHEMBL441896 Ki 415.0 nM
CNCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL3961059 Ki 420.0 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1cccc([N+](=O)[O-])c1 CHEMBL405355 Ki 430.53 nM
CCOC(=O)c1cccc(NC2=NC(N)=NC3(CCCCC3)N2)c1 CHEMBL3770106 Ki 457.0 nM
Cc1cccc2c1N=C(N)NC2 CHEMBL536335 Ki 463.0 nM
NC1=Nc2ccc(Cl)cc2CN1 CHEMBL2436555 Ki 466.0 nM
CC1NC(NCC(F)(F)F)=Nc2ccccc21 CHEMBL429925 Ki 488.0 nM
CC(C)N1CCN(Cc2ccc3[nH]cc(CCN(C)C)c3c2)S1(=O)=O CHEMBL318571 Log IC50 501.19 nM
CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 CHEMBL128 Log IC50 501.19 nM
COc1cccc(CCN(Cc2ccc(-c3ccc(CNCCc4ccccc4)cc3)cc2)C(=O)/C=C/c2ccccc2)c1 CHEMBL185996 Log Ki 501.19 nM
C[C@H]1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c21 CHEMBL256047 Ki 504.0 nM
COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 CHEMBL3326993 Ki 517.0 nM
NC1=Nc2cccc(F)c2CN1 CHEMBL539103 Ki 550.0 nM
COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCCN1CCCC1 CHEMBL214957 Ki 557.12 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21 CHEMBL19215 Activity 562.0 nM
COc1cc2c(cc1O)C[C@H]1c3c(cc(OC)c(OC)c3-2)CCN1C CHEMBL464099 Ki 566.0 nM
O=S1(=O)CC[C@@H](CNCc2cccc3cccnc23)C1 CHEMBL5085238 Ki 570.0 nM
CCOC(=O)c1cccc(NC2=NC(N(C)C)=NC3(CCCCC3)N2)c1 CHEMBL3770981 Ki 595.0 nM
Clc1ccc2c(c1)C(N1CCNCC1)=Nc1ccccc1O2 CHEMBL1113 AC50 618.2 nM
Cn1c2c(c3ccccc31)CCN(CCCOc1ccccc1)C2 CHEMBL126823 Ki 620.0 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL13816 Ki 630.0 nM
CN(C)CCc1c[nH]c2ccc(N3CCN(C)S3(=O)=O)cc12 CHEMBL319223 Log IC50 630.96 nM
CN1CCN(Cc2ccc3[nH]cc(CCN)c3c2)S1(=O)=O CHEMBL103854 Log IC50 630.96 nM
CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)c1ccccc1 CHEMBL365084 Log Ki 630.96 nM
NC1=Nc2cc(F)ccc2CN1 CHEMBL536562 Ki 647.0 nM
NC1=Nc2ccccc2CN1 CHEMBL557381 Ki 658.0 nM
Clc1ccc(-c2n[nH]cc2N2CCNCC2)cc1 CHEMBL4858338 Ki 685.0 nM
CCNCCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5094234 Ki 700.0 nM
O=S1(=O)CCC[C@@H](CNCc2cccc3cccnc23)C1 CHEMBL5091270 Ki 705.0 nM
CN1CCc2c(c3cccc4c3n2-c2ccccc2CC4)C1 CHEMBL3104091 pKi 741.31 nM
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 CHEMBL540612 Ki 754.39 nM
CNCCc1c[nH]c2ccc(CN3CCN(C)S3(=O)=O)cc12 CHEMBL102586 Log IC50 794.33 nM
CN(C)CCc1c[nH]c2ccc(CN3CCN(C)S3(=O)=O)cc12 CHEMBL103205 Log IC50 794.33 nM
CN(C)CCc1c[nH]c2ccc(CN3CCNS3(=O)=O)cc12 CHEMBL102548 Log IC50 794.33 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC CHEMBL1558 Ki 799.65 nM
CCCC1NC(N)=Nc2ccccc21 CHEMBL270840 Ki 805.0 nM
NC1=Nc2ccc(Cl)cc2CN1 CHEMBL536539 Ki 807.0 nM
CN(C)CCCN1c2ccccc2Sc2ccccc21 CHEMBL564 AC50 822.5 nM
CC1=NCCc2c1[nH]c1ccccc21 CHEMBL295234 Ki 845.0 nM
Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4cccc(O)c4)cc3c2OCCCN)c1 CHEMBL1766103 Ki 847.23 nM
COc1cccc(-c2ccc3c(c2)CN(Cc2ccccc2)C3)c1 CHEMBL4167315 Ki 875.0 nM
Cc1ccc2c(c1)CNC(N)=N2 CHEMBL557746 Ki 882.0 nM
NC1=Nc2c(Cl)cccc2CN1 CHEMBL272752 Ki 892.0 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1644978 Ki 894.0 nM
CNCCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5091373 Ki 910.0 nM
NC1=Nc2ccc(F)cc2CN1 CHEMBL536790 Ki 911.0 nM
Cn1c2c(c3ccccc31)CN(CCOc1ccc(F)cc1)CC2 CHEMBL126994 Ki 930.0 nM
O=C(CCCCCN1CCN(c2ccccc2O)CC1)n1c2ccccc2c2ccccc21 CHEMBL3764335 Ki 933.0 nM
COc1ccccc1-c1cc(C2CCNC2)ccc1Cl CHEMBL5077293 Ki 970.0 nM
C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 CHEMBL1200776 Ki 971.52 nM
CNCc1ccccc1-c1csc([C@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1 CHEMBL4520788 pKi 977.24 nM
CCNC(=O)c1cccc(NC2=NC(N)=NC3(CCCCC3)N2)c1 CHEMBL3771331 Ki 994.0 nM
CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 CHEMBL42 Ki 1000.0 nM
CCCN(CCC)C1CCc2cccc(O)c2C1 CHEMBL56 Ki 1000.0 nM
CN(C)CCc1c[nH]c2ccc(CN3C(C)(C)CNS3(=O)=O)cc12 CHEMBL102645 Log IC50 1000.0 nM
O=C(/C=C/c1ccccc1)N(Cc1ccc(-c2ccc(CNCc3ccc4c(c3)OCO4)cc2)cc1)Cc1cccnc1 CHEMBL186261 Log Ki 1000.0 nM
O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 CHEMBL1112 pKi 1000.0 nM
Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2 CHEMBL85 pKi 1000.0 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL47050 Ki 1000.0 nM
COc1ccccc1-c1cc(C2CCN(C)C2)ccc1Cl CHEMBL5083607 Ki 1000.0 nM