CSc1ccc2c(c1)C(N1CCN(C)CC1)Cc1ccccc1S2 CHEMBL93240 Kb 0.075 nM
O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1ccc(F)c(Cl)c1 CHEMBL3289972 Ki 0.1 nM
NCCc1c[nH]c2ccc(O)cc12 CHEMBL39 Ki 0.11 nM
Cc1ccc2c(c1)c1c(n2CCc2ccccc2)CCN(C)C1 CHEMBL592752 Ki 0.153 nM
O=S(=O)(c1ccccc1F)N1CCC[C@@H]1CCCN1CCN(c2ccccn2)CC1 CHEMBL5179460 Ki 0.17 nM
C[C@H](Nc1ccnc(NCCOc2ccc(F)cc2)c1)c1ccccc1 CHEMBL363452 pKi 0.1995 nM
Cc1c(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)sc2ccc(F)cc12 CHEMBL3290016 Ki 0.2 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL282199 Kb 0.2 nM
Cc1ccc2c(c1)c1c(n2/C=C\c2ccccc2)CCN(C)C1 CHEMBL605405 pKi 0.2089 nM
CSc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1 CHEMBL225284 Ki 0.22 nM
O=S(=O)(c1ccccc1F)N1CCC[C@@H]1CCCN1CCN(c2ccc(Cl)cc2)CC1 CHEMBL5196234 Ki 0.22 nM
Fc1ccc2[nH]cc(CCN3CCN(c4ccccc4-c4ccccc4)CC3)c2c1 CHEMBL4291322 Ki 0.26 nM
C[C@H](Nc1ccnc(NCCOc2ccc(F)cc2)n1)c1ccccc1 CHEMBL183277 Ki 0.3 nM
C[C@H](Nc1ccnc(NCCc2ccccc2)c1)c1ccccc1 CHEMBL182923 Ki 0.3 nM
CCCN(CCC)[C@H]1CCc2c(cccc2-c2cccc3ccccc23)C1 CHEMBL596959 Ki 0.3 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1 CHEMBL2159465 Ki 0.3 nM
NCCc1c[nH]c2ccc(C(N)=O)cc12 CHEMBL1256863 Ki 0.3 nM
COc1ccc(S(=O)(=O)N2CCc3ccc(I)cc32)cc1N1CCNCC1 CHEMBL414628 pKi 0.3162 nM
O=S(=O)(c1ccc(F)cc1)N1CCC[C@@H]1CCCN1CCN(c2ccc(Cl)cc2)CC1 CHEMBL5184712 Ki 0.32 nM
NCCc1c[nH]c2ccc(C(N)=O)cc12 CHEMBL18840 Ki 0.35 nM
O=C1Nc2ccccc2C1CCCCN1CCN(c2ccc(Cl)cc2)CC1 CHEMBL260994 Ki 0.38 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2ccccc21 CHEMBL261719 Ki 0.38 nM
Cc1ccc(CCn2c3c(c4cc(C)ccc42)CN(C)CC3)cc1 CHEMBL605081 pKi 0.389 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 0.39 nM
C[C@H](Nc1cc(NCCOc2ccccc2)ccn1)c1ccccc1 CHEMBL184607 Ki 0.4 nM
C[C@H](Nc1cc(NCCOc2ccc(F)cc2)ccn1)c1ccccc1 CHEMBL183423 Ki 0.4 nM
C[C@H](Nc1ccnc(NCCc2ccc(F)cc2)c1)c1ccccc1 CHEMBL181605 Ki 0.4 nM
C[C@H](Nc1ccnc(NCCOc2ccccc2)c1)c1ccccc1 CHEMBL181356 Ki 0.4 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2ccccc21 CHEMBL408976 Ki 0.4 nM
O=S(=O)(NCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 CHEMBL3290004 Ki 0.4 nM
Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2 CHEMBL85 Ki 0.4 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@H]1CCN1CCC(c2noc3cc(F)ccc23)CC1 CHEMBL4245263 Ki 0.4 nM
O=C1c2ccccc2CCCN1CCN1CCC(c2c[nH]c3ccccc23)CC1 CHEMBL267062 Log Ki 0.4074 nM
CCC1(CCCCN2CCN(c3ccc(F)cc3)CC2)C(=O)Nc2ccccc21 CHEMBL260872 Ki 0.43 nM
O=C1c2ccc(Cl)cc2CC1CCN1CCc2ccccc2C1 CHEMBL3898250 pKi 0.4677 nM
Cc1nn(C)c(C)c1-c1ccc(O)c(CCN(C)C)c1 CHEMBL4216782 Ki 0.47 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@@H]1CCN1CCN(c2cccc3sccc23)CC1 CHEMBL4248491 Kb 0.47 nM
O=C1Nc2ccccc2C1CCCCN1CCN(c2cccc(Cl)c2)CC1 CHEMBL261209 Ki 0.49 nM
Cc1cccc(S(=O)(=O)NCCCN2CCC(c3noc4cc(F)ccc34)CC2)c1 CHEMBL3289991 Kb 0.5 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12 CHEMBL3290002 Ki 0.5 nM
O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(c2nsc3ccccc23)CC1 CHEMBL1237021 Ki 0.5 nM
O=C1C2C3CCC(C3)C2C(=O)N1CC1CCCCC1CN1CCN(c2nsc3ccccc23)CC1 CHEMBL5219924 K 0.5 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(Oc2ccc(F)cc2)CC1 CHEMBL413707 Log Ki 0.5012 nM
Fc1cccc(-c2c(F)cccc2N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c1 CHEMBL4277476 Ki 0.55 nM
O=C1c2ccccc2CCCN1CCN1CCC(n2ccc3cc(F)ccc32)CC1 CHEMBL9951 Log Ki 0.5623 nM
N#Cc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccccc3)CC2)cc1 CHEMBL522691 Ki 0.58 nM
CN(C)CCSc1cccc(-c2ccccc2)n1 CHEMBL161765 Ki 0.6 nM
C[C@H](Nc1ccnc(NCCc2ccccc2)n1)c1ccccc1 CHEMBL185384 Ki 0.6 nM
CCC1(CCCCN2CCN(c3ccc(F)c(Cl)c3)CC2)C(=O)Nc2ccccc21 CHEMBL406414 Ki 0.6 nM
CCC1(CCCCN2CCN(c3ccc(Cl)c(Cl)c3)CC2)C(=O)Nc2ccccc21 CHEMBL259087 Ki 0.6 nM
Cc1nn(C)c(C)c1-c1cccc2c1CC[C@H](N(C)C)C2 CHEMBL2164327 Ki 0.6 nM
CCC1(OC)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 CHEMBL3343666 Ki 0.6 nM
COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 CHEMBL8618 Ki 0.6 nM
Cc1cccc(S(=O)(=O)NCCN2CC=C(c3c[nH]c4ccc(Cl)cc34)CC2)c1 CHEMBL4065568 Ki 0.6 nM
CCC1(CCCCN2CCN(c3ccc(C)c(Cl)c3)CC2)C(=O)Nc2ccccc21 CHEMBL259086 Ki 0.66 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2cc(F)ccc21 CHEMBL259549 Ki 0.67 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(c2c[nH]c3ccccc23)CC1 CHEMBL430706 Log Ki 0.6761 nM
CN(C)CCSc1cccc(C2CCCCC2)n1 CHEMBL158402 Ki 0.7 nM
O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1ccc(Cl)c(Cl)c1 CHEMBL3289970 Ki 0.7 nM
Cc1c(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)sc2ccc(Cl)cc12 CHEMBL3290017 Ki 0.7 nM
O=C1Cc2ccccc2N1CC/C=C/CCN1CCc2ccccc2C1 CHEMBL3321794 Ki 0.7 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(n2c(O)nc3ccccc32)CC1 CHEMBL115262 Log Ki 0.7079 nM
Clc1ccc(CCN2CCN(c3ccccc3-c3ccccc3)CC2)cc1Cl CHEMBL4215605 Ki 0.75 nM
COCC1(OC)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 CHEMBL3343667 Ki 0.76 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2cc(F)ccc21 CHEMBL409662 Ki 0.79 nM
Fc1cccc(-c2ccccc2N2CCN(CCc3c[nH]c4ccc(F)cc34)CC2)c1 CHEMBL4285796 Ki 0.79 nM
O=C(c1ccc(Cl)cc1)C1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc3cc[nH]c3c2)CC1 CHEMBL116292 Log Ki 0.7943 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc(F)c(Cl)c1 CHEMBL3289995 Kb 0.8 nM
O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1ccc2ccccc2c1 CHEMBL3289978 Ki 0.8 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12 CHEMBL3290003 Ki 0.8 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 CHEMBL3290005 Ki 0.8 nM
COc1ccc(/C=C2\NC(=O)N(CCCCN3CCN(c4cccc(Cl)c4Cl)CC3)C2=O)cc1OC CHEMBL4591601 Ki 0.8 nM
O=C(c1ccc(F)cc1)C1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc3cc[nH]c3c2)CC1 CHEMBL114345 Log Ki 0.8318 nM
O=c1[nH]c(CCCCN2CCN(c3ccccc3)CC2)nc2ccsc12 CHEMBL4443201 Ki 0.85 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccs1 CHEMBL3289999 Ki 0.9 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1csc2ccccc12 CHEMBL3290009 Ki 0.9 nM
Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(-c2cn[nH]c2)c1 CHEMBL4544153 Ki 0.9 nM
Cc1ccccc1N1CCN(CCCCn2c(=O)sc3ccccc32)CC1 CHEMBL3331258 Ki 0.99 nM
Fc1ccc2[nH]cc(CCN3CCN(c4nsc5ccccc45)CC3)c2c1 CHEMBL4574299 Ki 0.99 nM
CSc1ccc2c(c1)[C@@H](N1CCN(C)CC1)Cc1ccccc1S2 CHEMBL428892 Log Ki 1.0 nM
Cc1cccc(C#N)c1-c1cccc2c1-c1cccc3c1[C@@H](C2)N(C)CC3 CHEMBL28056 Ki 1.0 nM
CC(Nc1nccc(NCCOc2ccc(F)cc2)n1)c1ccccc1 CHEMBL182071 Ki 1.0 nM
CC(C)Oc1cccc2c1N=C(N)NC2C CHEMBL258075 Ki 1.0 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2cc(Cl)ccc2c1 CHEMBL3290008 Kb 1.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2ccccc2F)CC1 CHEMBL3742076 Kb 1.0 nM
CC(C)c1cccc(OCCN2C3CCC2CC(NS(=O)(=O)c2ccc(F)cc2)C3)c1 CHEMBL3759205 Ki 1.0 nM
O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1 CHEMBL4104622 Ki 1.0 nM
CC(C)c1ccccc1OCCCN1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1 CHEMBL4216126 Kb 1.0 nM
O=S(=O)(c1cccc2ncccc12)N1CCC[C@@H]1CCN1CCN(c2cccc3sccc23)CC1 CHEMBL4243848 Ki 1.0 nM
O=S(=O)(c1cccc2cnccc12)N1CCC[C@@H]1CCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4239091 Ki 1.0 nM
O=S(=O)(c1cccc2ncccc12)N1CCC[C@@H]1CCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4242858 Ki 1.0 nM
COc1ccc(/C=C2\NC(=O)N(CCCCN3CCN(c4ccccc4OC)CC3)C2=O)cc1OC1CCCC1 CHEMBL4465959 Ki 1.0 nM
NCCc1c[nH]c2ccc(C(=O)O)cc12 CHEMBL4442472 pKi 1.0 nM
CN(C)[C@H]1CCc2c(cccc2-c2ccccc2Cl)C1 CHEMBL4647808 Ki 1.0 nM
CC1CCN(CCC2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL5218527 Ki 1.0 nM
CCC1(CCCCN2CC=C(c3ccc(Cl)cc3)CC2)C(=O)Nc2ccccc21 CHEMBL410226 Ki 1.02 nM
COc1ccc(S(=O)(=O)Nc2cc(Br)ccc2Br)cc1N1CCNCC1 CHEMBL154274 pKi 1.023 nM
CO[C@@]1(C)c2cccc3c2-c2c1ccc1c2[C@@H](C3)N(C)CC1 CHEMBL281923 pKi 1.096 nM
CO[C@]1(C)c2cccc3c2-c2c1ccc1c2[C@@H](C3)N(C)CC1 CHEMBL281924 Ki 1.1 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2ccc(Cl)cc21 CHEMBL269083 Ki 1.1 nM
Cc1cccc(S(=O)(=O)NCCCCN2CCN(c3noc4ccccc34)CC2)c1 CHEMBL3289968 Ki 1.1 nM
Cc1cccc(S(=O)(=O)NCCN2CCC(c3noc4cc(F)ccc34)CC2)c1 CHEMBL3289990 Ki 1.1 nM
Fc1ccc2[nH]cc(CCCN3CCN(c4ccccc4-c4ccccc4)CC3)c2c1 CHEMBL4286174 Ki 1.1 nM
Fc1cccc(-c2ccccc2N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c1 CHEMBL4278933 Ki 1.1 nM
Cc1ccc(N2CCN(CCCCC3C(=O)Nc4ccccc43)CC2)cc1 CHEMBL5201016 Ki 1.1 nM
CSc1ccc2c(c1)CC(N1CCN(C)CC1)c1ccccc1S2 CHEMBL5208064 pKi 1.122 nM
COc1ccc(-c2ccccc2N2CCN(CCCCCC(=O)NCc3ccncc3)CC2)cc1 CHEMBL2442996 Kd 1.17 nM
CCC1(CCCCN2CC=C(c3ccc(F)cc3)CC2)C(=O)Nc2ccccc21 CHEMBL410225 Ki 1.19 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc(Cl)c(Cl)c1 CHEMBL3289993 Ki 1.2 nM
CCC1(O)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 CHEMBL3343663 Ki 1.2 nM
CCC1(CCCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2ccccc21 CHEMBL262068 Ki 1.24 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL1256844 Log Ki 1.259 nM
Cc1nn(C)c(C)c1-c1cccc(CCN(C)C)c1 CHEMBL4205349 pKi 1.288 nM
CN(C)CCSC(C)(C)C CHEMBL158973 Ki 1.3 nM
O=S(=O)(NCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12 CHEMBL3290001 Ki 1.3 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cc2ccc(Cl)cc2s1 CHEMBL3290014 Ki 1.3 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2scnc12 CHEMBL3290020 Ki 1.3 nM
NC(N)=NC(=O)c1ccc2c(c1)C1(CCOCC1)c1ccccc1-2 CHEMBL3343671 Ki 1.3 nM
Cc1ccccc1-c1cccc(N2CCNCC2)c1 CHEMBL2164330 Ki 1.4 nM
c1ccc(-c2ccccc2N2CCNCC2)cc1 CHEMBL494675 Ki 1.4 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 CHEMBL3290006 Ki 1.4 nM
COC1(C)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 CHEMBL3343665 Ki 1.4 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1ccc(F)c(Cl)c1 CHEMBL4775997 pKi 1.445 nM
CCC1(CCCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2ccccc21 CHEMBL258496 Ki 1.45 nM
CCC1(CCCCN2CCN(c3ccc(F)cc3)CC2)C(=O)Nc2ccc(F)cc21 CHEMBL259216 Ki 1.5 nM
O=S(=O)(NCCN1CCN(c2nsc3ccccc23)CC1)c1ccc2ccccc2c1 CHEMBL3289952 Ki 1.5 nM
O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc2ccccc2c1 CHEMBL3289953 Ki 1.5 nM
Cc1cccc(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)c1 CHEMBL3289992 Ki 1.5 nM
O=C1c2ccc(F)cc2CC1CCN1CCc2ccccc2C1 CHEMBL3958215 pKi 1.585 nM
CCNCCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5094234 pKi 1.585 nM
COc1ccccc1N1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1806820 Kb 1.6 nM
Cc1cccc(S(=O)(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)c1 CHEMBL3289944 Ki 1.6 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cc2ccccc2s1 CHEMBL3290012 Ki 1.6 nM
CCCCc1cc(-c2ccoc2)nc(N2CCN(C)CC2)n1 CHEMBL4204059 Ki 1.6 nM
CNCCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5091373 Ki 1.6 nM
O=C(c1ccc(F)cc1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 CHEMBL9616 Log Ki 1.66 nM
Cc1cccc(S(=O)(=O)N[C@@H]2CCN(CCCc3noc4ccccc34)C2)c1 CHEMBL4750664 pKi 1.698 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1cccc2ccccc12 CHEMBL4754138 pKi 1.698 nM
Cc1cccc(S(=O)(=O)NCCCN2CCN(c3nsc4ccccc34)CC2)c1 CHEMBL3289709 Ki 1.7 nM
NC(N)=NC(=O)c1ccc2c(c1)C1(CCCO1)c1ccccc1-2 CHEMBL3343670 Ki 1.7 nM
O=c1sc2ccccc2n1CCCCN1CCN(c2cccc(Cl)c2)CC1 CHEMBL3331261 Ki 1.72 nM
CC(C)CC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2ccccc21 CHEMBL408191 Ki 1.8 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc2ccccc2c1 CHEMBL3289954 Ki 1.8 nM
NC(N)=NC(=O)c1ccc2c(c1)C1(CCCC1)c1ccccc1-2 CHEMBL3343669 Ki 1.8 nM
O=c1oc2ccccc2n1C1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc3cc[nH]c3c2)CC1 CHEMBL323778 Log Ki 1.82 nM
NC(=O)c1sccc1NC(=O)CCCCN1CCN(c2ccccc2)CC1 CHEMBL4590226 Ki 1.86 nM
O=C1Nc2cccc3c2C1(CCCCN1CCN(c2ccccn2)CC1)CCC3 CHEMBL428494 Log Ki 1.862 nM
Cc1ccc(-c2ccccc2N2CCNCC2)cc1C CHEMBL2164334 Ki 1.9 nM
COc1ccccc1N1CCN(CCC[C@H]2CCCN2S(=O)(=O)c2ccccc2F)CC1 CHEMBL5196950 Ki 1.9 nM
O=C1Nc2ccc(F)cc2C1CCCCN1CCN(c2cccc(Cl)c2)CC1 CHEMBL408450 Ki 1.96 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@H]1CCN1CCC(Oc2ccc(Cl)cc2)CC1 CHEMBL4521657 Ki 1.99 nM
O=C1Nc2cccc3c2C1(CCCCN1CC=C(c2ccccc2)CC1)CCC3 CHEMBL69257 Log Ki 1.995 nM
CC1CCN(CC[C@@H]2CCCN2S(=O)(=O)c2cccc(Br)c2)CC1 CHEMBL347286 Log Ki 1.995 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(Br)c2)CC1 CHEMBL116448 Log Ki 1.995 nM
COc1ccc(S(=O)(=O)Nc2cc(Cl)cc(Cl)c2Cl)cc1N1CCNCC1 CHEMBL157910 pKi 1.995 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(Oc2ccc(Cl)cc2)CC1 CHEMBL95104 Log Ki 1.995 nM
O=C1Nc2cccc3c2C1(CCCCN1CCC(c2ccccc2)CC1)CCC3 CHEMBL12846 pKi 1.995 nM
COc1ccc2[nH]cc(CCN)c2c1 CHEMBL8165 Ki 2.0 nM
C[C@H](Nc1nc(N)nc(NCCOc2ccc(F)cc2)n1)c1ccc(F)cc1 CHEMBL182937 Ki 2.0 nM
C[C@H](Nc1nc(N)nc(NCCc2ccc(F)cc2)n1)c1ccc(F)cc1 CHEMBL413049 Ki 2.0 nM
CC(Nc1nc(N)nc(NCCc2cccs2)n1)c1ccc(F)cc1 CHEMBL180086 Ki 2.0 nM
C[C@H](Nc1ccnc(NCCOc2ccccc2)n1)c1ccccc1 CHEMBL185511 Ki 2.0 nM
O=S(=O)(N[C@@H]1CCN(CCOc2ccccc2-c2ccccc2)C1)c1ccc(F)cc1 CHEMBL2159489 Ki 2.0 nM
O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1cccc2scnc12 CHEMBL3289965 Ki 2.0 nM
CC(C)c1cccc(OCCN2C3CCC2CC(NS(=O)(=O)c2cccc(F)c2)C3)c1 CHEMBL3759617 Ki 2.0 nM
O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(F)c1 CHEMBL4095555 Ki 2.0 nM
O=S(=O)(NCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1 CHEMBL4080399 Ki 2.0 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(Cc2ccc(Cl)cc2)CC1 CHEMBL4218549 Ki 2.0 nM
CC(Nc1nc(N)nc(NCCOc2ccc(F)cc2)n1)c1ccc(F)cc1 CHEMBL182322 Ki 2.0 nM
Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(-c2ccsc2)c1 CHEMBL4471208 Ki 2.0 nM
O=C1Nc2ccc(Cl)c3c2C1(CCCCN1CC=C(c2ccc(F)cc2)CC1)CCC3 CHEMBL422869 Log Ki 2.042 nM
O=C1c2ccccc2CCCN1CCN1CCC(n2nnc3cc(F)ccc32)CC1 CHEMBL9347 Log Ki 2.042 nM
CCC1(CCCCN2CCN(c3ccccc3)CC2)C(=O)Nc2ccccc21 CHEMBL410628 Ki 2.07 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2ccc(F)cc21 CHEMBL259550 Ki 2.1 nM
N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(=O)O CHEMBL350221 Ki 2.12 nM
COc1ccccc1N1CCN(CCCCC23CCCc4cccc(c42)NC3=O)CC1 CHEMBL12702 Log Ki 2.138 nM
O=C1Nc2cccc3c2C1(CCCCN1CCN(c2ccccc2)CC1)CCC3 CHEMBL12427 pKi 2.138 nM
O=C1Nc2cccc3c2[C@]1(CCCCN1CC=C(c2ccccc2)CC1)CCC3 CHEMBL25815 pKi 2.138 nM
CSc1ccc2c(c1)C(CCN)=CC2 CHEMBL122536 IC50 2.2 nM
Fc1ccc2[nH]cc(CCCN3CCN(c4nsc5ccccc45)CC3)c2c1 CHEMBL4476294 Ki 2.2 nM
O=C1c2ccccc2CCCN1CCN1CCC(n2c(O)nc3cc(F)ccc32)CC1 CHEMBL273921 Log Ki 2.239 nM
CCc1cccc2c1-c1ccc(C(=O)N=C(N)N)cc1C2(C)O CHEMBL3310714 Ki 2.3 nM
Fc1ccc2[nH]cc(CCN3CCN(c4ccccc4-c4ccccc4F)CC3)c2c1 CHEMBL4294077 Ki 2.3 nM
COc1cccc(N2CCN(CCCCC34CCCc5cccc(c53)NC4=O)CC2)c1 CHEMBL71847 Log Ki 2.344 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc3cc[nH]c3c2)CC1 CHEMBL330353 Log Ki 2.399 nM
CC1NC(N)=Nc2c(Cl)ccc(Cl)c21 CHEMBL272781 Ki 2.4 nM
CNC1=Nc2c(OC(C)C)cccc2C(C)N1 CHEMBL402179 Ki 2.4 nM
COc1cc(Cl)c(C)c2c1N=C(N)NC2C CHEMBL401745 Ki 2.5 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@H]1CCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4246655 Kb 2.5 nM
COc1ccccc1-c1cc(CCN(C)C)ccc1Cl CHEMBL5074190 Ki 2.5 nM
COc1cc(OC)c(C2NCCc3c2[nH]c2ccc(Cl)cc32)cc1OC CHEMBL5207529 Ki 2.5 nM
O=C(c1ccc(Cl)cc1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 CHEMBL275343 Log Ki 2.512 nM
CCC1(CCCCN2CCN(c3cccc(OC)c3)CC2)C(=O)Nc2ccccc21 CHEMBL260762 Ki 2.55 nM
COc1cccc(OC)c1-c1cccc2c1OC[C@H](N(C)C)C2 CHEMBL183329 Ki 2.55 nM
COc1ccc(-c2ccccc2N2CCNCC2)cc1 CHEMBL2164336 Ki 2.6 nM
Cc1c(S(=O)(=O)NCCCCN2CCN(c3noc4ccccc34)CC2)sc2ccc(F)cc12 CHEMBL3289986 Ki 2.6 nM
Fc1cccc(-c2ccc(F)cc2N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c1 CHEMBL4288120 Ki 2.6 nM
COc1ccccc1N1CCN(CCC[C@H]2CCCN2S(=O)(=O)c2ccc(F)cc2)CC1 CHEMBL5172635 Ki 2.6 nM
COc1cccc(N2CCN(CCCCC3C(=O)Nc4ccccc43)CC2)c1 CHEMBL5179267 Ki 2.6 nM
CN1CC[C@H]2c3ccccc3N(c3ccccc3)C[C@]21C CHEMBL4459009 pKi 2.692 nM
Fc1ccc(-c2ccccc2N2CCNCC2)cc1 CHEMBL2164332 Ki 2.7 nM
O=C1Cc2ccccc2N1CC/C=C/CCN1CC[C@H]2CCCC[C@@H]2C1 CHEMBL3321798 Ki 2.7 nM
O=C1c2ccccc2CCCN1CCN1CCC(n2ccc3ccccc32)CC1 CHEMBL9952 Log Ki 2.754 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1cccc(Cl)c1 CHEMBL4784228 pKi 2.754 nM
COc1ccccc1-c1cc(C2CCNC2)ccc1Cl CHEMBL5077293 pKi 2.754 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2ccc(F)cc21 CHEMBL259010 Ki 2.81 nM
O=c1sc2ccccc2n1CCCCN1CCc2ccccc2C1 CHEMBL3331262 Ki 2.84 nM
CN(CCCN1CCN(c2cccc3ccccc23)CC1)c1cccc(O)c1 CHEMBL3262408 Ki 2.9 nM
COc1ccccc1N1CCN(CCCCCCn2c(=O)sc3ccccc32)CC1 CHEMBL3331387 Ki 2.9 nM
CCCN(CCC)[C@H]1CCc2c(cccc2-c2ccccc2)C1 CHEMBL362540 Ki 2.91 nM
O=c1sc2ccccc2n1CCCCCCN1CCN(c2ccccc2)CC1 CHEMBL3331385 Ki 2.96 nM
CCOc1ccccc1N1CCN(CCCCCn2cnc3sc(C)c(C)c3c2=O)CC1 CHEMBL3401493 Ki 2.99 nM
Brc1ccc2ccn(CCN3CCCN4CCCCC4C3)c2c1 CHEMBL309750 Ki 3.0 nM
Cc1cccc(S(=O)(=O)N2CCC[C@@H]2CCN2CCC(C)CC2)c1 CHEMBL12624 Ki 3.0 nM
C[C@H](Nc1nc(N)nc(NCCOc2ccccc2)n1)c1ccccc1 CHEMBL182174 Ki 3.0 nM
C[C@H](Nc1ncnc(NCCOc2ccccc2)n1)c1ccccc1 CHEMBL183862 Ki 3.0 nM
C[C@H](Nc1cc(NCCc2ccccc2)ccn1)c1ccccc1 CHEMBL181950 Ki 3.0 nM
COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(c3ccc(F)cc3)C2=O)CC1 CHEMBL3233679 Ki 3.0 nM
O=S(=O)(c1cccc2cnccc12)N1CCC[C@@H]1CCN1CCN(c2cccc3sccc23)CC1 CHEMBL4238479 Ki 3.0 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@@H]1CCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4238679 Ki 3.0 nM
COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(c3ccc4ccccc4c3)C2=O)CC1 CHEMBL4284331 Ki 3.0 nM
CC1(c2ccc3ccccc3c2)NC(=O)N(CC(O)CN2CCN(c3ccccc3C#N)CC2)C1=O CHEMBL4292237 Ki 3.0 nM
COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(c3ccc(F)cc3)C2=O)CC1 CHEMBL3302600 Ki 3.0 nM
CC(Nc1nc(N)nc(NCCOc2ccccc2)n1)c1ccccc1 CHEMBL182797 Ki 3.0 nM
COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1 CHEMBL431298 Ki 3.0 nM
Clc1ccc(-c2nn(Cc3ccccc3)c3c2CCNCC3)cc1 CHEMBL4205783 Ki 3.0 nM
Oc1cccc(CCCCN2CCN(c3ccccc3)CC2)c1 CHEMBL3262410 Ki 3.1 nM
NCCCC1(CCCN)CCc2cccc(O)c2C1 CHEMBL146942 Log Ki 3.162 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1cccs1 CHEMBL3289951 Ki 3.2 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cnc2ccccn12 CHEMBL3290018 Ki 3.2 nM
OC(CN1CCN(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1 CHEMBL4203932 Ki 3.2 nM
NC(N)=NC(=O)c1ccc2c(c1)[C@]1(CCCO1)c1ccccc1-2 CHEMBL3343672 Ki 3.3 nM
Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(-c2ccccc2)c1 CHEMBL4289783 Ki 3.3 nM
O=C1NC2C=CC=C3CCCC1(CCCCN1CCN(c4ccccc4)CC1)C32 CHEMBL4527987 Ki 3.3 nM
CCCN(CCC)[C@H]1COc2c(cccc2-c2ccccc2)C1 CHEMBL186112 Ki 3.38 nM
O=C1Nc2ccc(F)cc2C1CCCCN1CCN(c2ccc(F)cc2)CC1 CHEMBL408426 Ki 3.4 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1cccc2scnc12 CHEMBL3289966 Ki 3.4 nM
COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3ccccc32)CC1 CHEMBL478680 Ki 3.4 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@H]1CCN1CCN(c2cccc3sccc23)CC1 CHEMBL4239823 Kb 3.4 nM
Cn1c(CCCCN2CCN(c3ccccc3)CC2)nc2c(sc3ccccc32)c1=O CHEMBL4437217 Ki 3.43 nM
CNC(=O)Cn1c2c(c3ccccc31)CN(CCCCC13CCCc4cccc(c41)NC3=O)CC2 CHEMBL4533865 Ki 3.54 nM
O=C1Nc2cccc3c2C1(CCCCN1CC=C(c2ccc(F)cc2)CC1)CCC3 CHEMBL418888 Log Ki 3.548 nM
CNC(=O)Cn1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 CHEMBL553794 Log Ki 3.548 nM
O=C(CCCN1CCc2ccccc2C1)c1ccc(Cl)cc1 CHEMBL3818047 pKi 3.548 nM
O=C(c1ccc(F)cc1)C1CCN(CCc2ccccc2I)CC1 CHEMBL74756 Ki 3.68 nM
O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1 CHEMBL2105760 Ki 3.7 nM
Cc1cccc(S(=O)(=O)NCCN2CCN(c3nsc4ccccc34)CC2)c1 CHEMBL3289708 Ki 3.8 nM
[2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCN(C([2H])([2H])[2H])C(C)(C)C3)c3cc(Cl)ccc32)c([2H])c1[2H] CHEMBL5191141 Ki 3.8 nM
N#Cc1ccccc1N1CCN(CCCCC23CCCc4cccc(c42)NC3=O)CC1 CHEMBL273246 Log Ki 3.802 nM
COc1ccc(-c2ccccc2N2CCN(CCCCCC(=O)NCc3ccc(F)nc3)CC2)cc1 CHEMBL3113593 Ki 3.82 nM
CC1CCN(CC[C@@H]2CCCN2S(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 CHEMBL153398 Log Ki 3.981 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 CHEMBL333784 Log Ki 3.981 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1ccc(F)cc1 CHEMBL4758402 pKi 3.981 nM
C[C@H](Nc1cc(NCCc2ccc(F)cc2)ccn1)c1ccccc1 CHEMBL185512 Ki 4.0 nM
C[C@H](Nc1cncc(NCCOc2ccccc2)c1)c1ccccc1 CHEMBL359725 Ki 4.0 nM
C[C@H](Nc1cncc(NCCOc2ccc(F)cc2)c1)c1ccccc1 CHEMBL184789 Ki 4.0 nM
CCC1(CCCCN2CCN(c3ccccn3)CC2)C(=O)Nc2ccccc21 CHEMBL1836789 Ki 4.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(Cl)c2)C1 CHEMBL2159485 Ki 4.0 nM
O=S(=O)(N[C@@H]1CCN(CCOc2ccccc2-c2ccccc2)C1)c1ccc(Cl)s1 CHEMBL2159488 Ki 4.0 nM
Cc1cccc2c1-c1ccc(C(=O)N=C(N)N)cc1C2(C)O CHEMBL3310713 Ki 4.0 nM
CC(C)c1cccc(OCCN2C3CCC2CC(NS(=O)(=O)c2cc(F)ccc2F)C3)c1 CHEMBL3759233 Ki 4.0 nM
CC(C)c1cccc(OCCN2C3CCC2CC(NS(=O)(=O)c2cccc(Cl)c2)C3)c1 CHEMBL3758286 Ki 4.0 nM
CNC(=O)CN1c2ccccc2C2CCN(CCCCC34CCCc5cccc(c53)NC4=O)CC21 CHEMBL4211987 Ki 4.0 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@@H]1CCN1CCN(c2cccc3[nH]ccc23)CC1 CHEMBL4245997 Ki 4.0 nM
CCn1cncc1-c1c[nH]c2ccc(I)c(F)c12 CHEMBL4452569 Ki 4.0 nM
CN(C)CCSc1cccc(Br)n1 CHEMBL158285 Ki 4.1 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1cnc2ccccn12 CHEMBL3289964 Ki 4.1 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cc2ccccc2s1 CHEMBL3290011 Ki 4.1 nM
CCc1cccc2c1-c1ccc(C(=O)N=C(N)N)cc1C2O CHEMBL3310113 Ki 4.1 nM
CC1c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 CHEMBL3310122 Ki 4.1 nM
CC(C)Oc1cccc2c1N=C(NCC(F)F)NC2C CHEMBL446459 Ki 4.2 nM
CN(C)C1CCc2c(cccc2-c2ccccc2Cl)C1 CHEMBL4641654 Ki 4.2 nM
COc1ccccc1N1CCN(Cc2ccn(-c3ccccc3C)c2)CC1 CHEMBL177064 Ki 4.3 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1csc2ccccc12 CHEMBL3290010 Ki 4.3 nM
CC1(O)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 CHEMBL3310123 Ki 4.3 nM
CCC1(CCCCN2CCc3sccc3C2)C(=O)Nc2ccccc21 CHEMBL410128 Ki 4.31 nM
O=C(CCN1CCN(Cc2ccccc2)CC1)NCc1ccccc1 CHEMBL4572955 Ki 4.34 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc(F)c(Cl)c1 CHEMBL3289996 Ki 4.4 nM
O=C1c2ccccc2CCCN1CCN1CCC(Oc2ccc(F)cc2)CC1 CHEMBL275451 Log Ki 4.467 nM
O=C1Nc2cccc3c2C1(CCCCN1CCc2ccccc2C1)CCC3 CHEMBL314830 Log Ki 4.467 nM
CN1CCc2c(sc3ncn(CCN4CCN(c5ccnc6ccccc56)CC4)c(=O)c23)C1 CHEMBL198463 Ki 4.48 nM
COc1ccccc1N1CCN(Cc2cn(-c3cccc4ccccc34)c3ccccc23)CC1 CHEMBL3121424 Ki 4.5 nM
COCOc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccccc3)CC2)cc1 CHEMBL3985152 Ki 4.5 nM
COc1ccccc1N1CCN(Cc2cn(-c3cccc4ccccc34)c3ccccc23)CC1 CHEMBL3139441 Ki 4.5 nM
CN1CCc2cccc3c2C1Cc1ccc(NC(N)=O)cc1-3 CHEMBL4636148 Ki 4.5 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1ccc(F)c(F)c1 CHEMBL2159466 Kb 4.6 nM
Cc1c(S(=O)(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)sc2ccc(F)cc12 CHEMBL3289962 Ki 4.6 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2c(Cl)cc(F)cc21 CHEMBL259215 Ki 4.75 nM
Cc1ccc(C2=CCN(CCCCC34CCCc5cccc(c53)NC4=O)CC2)cc1 CHEMBL304731 Log Ki 4.786 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1cc2ccccc2s1 CHEMBL4795995 pKi 4.786 nM
O=C1CCc2cc(C(=O)CCCN3CCN(c4ccccn4)CC3)ccc2N1 CHEMBL4845947 pKi 4.786 nM
COc1ccccc1N1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc(F)cc2)CC1 CHEMBL1806819 Kb 4.8 nM
NC(N)=NC(=O)c1ccc2c(c1)C1(CC1)c1ccccc1-2 CHEMBL3343668 Ki 4.9 nM
O=C1Nc2cccc3c2C1(CCCN1CCN(c2ccccc2)CC1)CCC3 CHEMBL13052 Ki 5.0 nM
C[C@H](Nc1cc(NCCc2ccc(F)cc2)ncn1)c1ccccc1 CHEMBL182680 Ki 5.0 nM
C[C@H](Nc1cc(NCCOc2ccc(F)cc2)ncn1)c1ccccc1 CHEMBL182943 Ki 5.0 nM
O=C1Nc2ccccc2C1CCCCN1CCN(c2ccc(F)cc2)CC1 CHEMBL1836785 Ki 5.0 nM
CSc1ccccc1OCCN1CCC(NS(=O)(=O)c2ccc(Cl)s2)C1 CHEMBL2159322 Ki 5.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)C1)c1ccc(F)cc1 CHEMBL2159323 Ki 5.0 nM
O=C([C@@H]1CCCN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCCCC1 CHEMBL3409039 Ki 5.0 nM
CN(C1CCN(CCOc2ccccc2-c2ccccc2)CC1)S(=O)(=O)c1ccc(F)cc1 CHEMBL3745815 Ki 5.0 nM
Cc1cccc(S(=O)(=O)NCCCN2CC=C(c3c[nH]c4ccc(Cl)cc34)CC2)c1 CHEMBL4077040 Ki 5.0 nM
O=C1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1 CHEMBL708 Ki 5.0 nM
COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(c3cccc4ccccc34)C2=O)CC1 CHEMBL4280511 Ki 5.0 nM
CCn1cncc1-c1c[nH]c2ccc(C(N)=O)cc12 CHEMBL4469847 Ki 5.0 nM
O=C1Nc2ccc(Cl)c3c2C1(CCCCN1CC=C(c2ccccc2)CC1)CCC3 CHEMBL348410 Log Ki 5.012 nM
O=S(=O)(N[C@H]1CCN(CCCc2noc3ccccc23)C1)c1ccc2ccccc2c1 CHEMBL4763085 pKi 5.012 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1csc2ccccc12 CHEMBL4793608 pKi 5.012 nM
CCC1(CCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)C(=O)Nc2ccccc21 CHEMBL1836786 Ki 5.1 nM
O=S(=O)(NCC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1ccc(F)cc1 CHEMBL2159458 Kb 5.1 nM
O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1cc2ccc(Cl)cc2s1 CHEMBL3289984 Ki 5.1 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc(Cl)c(Cl)c1 CHEMBL3289994 Ki 5.1 nM
NC(N)=NC(=O)c1ccc2c(c1)[C@@]1(CCCO1)c1ccccc1-2 CHEMBL3343673 Ki 5.1 nM
CCC1(CCCCN2CCN(c3ccccc3Cl)CC2)C(=O)Nc2ccccc21 CHEMBL407412 Ki 5.11 nM
COc1ccccc1N1CCN(CCCCCn2c(=O)sc3ccccc32)CC1 CHEMBL3331383 Ki 5.16 nM
CNCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL3961059 Ki 5.2 nM
CN(C)[C@H]1CCc2c(cccc2-c2cccc3ccccc23)C1 CHEMBL611472 Ki 5.2 nM
CCC1(CCCCN2CCC(c3ccc(F)cc3)CC2)C(=O)Nc2ccccc21 CHEMBL258537 Ki 5.3 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(F)c(Cl)c1 CHEMBL3286432 Ki 5.3 nM
CCCN(CCC)[C@H]1CCc2c(cccc2-c2ccccc2F)C1 CHEMBL4639661 Ki 5.3 nM
CN(C)[C@H]1CCc2c(cccc2-c2ccccc2F)C1 CHEMBL4639638 Ki 5.3 nM
CCC1(CCCCN2CCN(c3ccccc3OC)CC2)C(=O)Nc2ccccc21 CHEMBL265927 Ki 5.38 nM
COc1ccccc1N1CCN(Cc2ccn(-c3ccccc3C#N)c2)CC1 CHEMBL181874 Ki 5.4 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1ccc2ccccc2c1 CHEMBL4747225 pKi 5.495 nM
CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 CHEMBL42 Ki 5.5 nM
CN(C)CCSc1nc2ccsc2n2cccc12 CHEMBL4526441 Ki 5.6 nM
O=C1Nc2cccc3c2C1(CCCCN1CCc2c([nH]c4ccccc24)C1)CCC3 CHEMBL71383 Log Ki 5.754 nM
O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1cnc2ccccn12 CHEMBL3289987 Ki 5.9 nM
COc1ccccc1N1CCN(CCCCCn2c(=O)oc3ccccc32)CC1 CHEMBL3331382 Ki 5.9 nM
CCCN(CCC)[C@H]1CCc2c(cccc2-c2ccccc2Cl)C1 CHEMBL4637900 Ki 5.9 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2c(Cl)cc(F)cc21 CHEMBL260761 Ki 5.97 nM
CC(Nc1nccc(NCCc2ccccc2)n1)c1ccccc1 CHEMBL182070 Ki 6.0 nM
CC(Nc1ccnc(NCCc2ccc(F)cc2)n1)c1ccccc1 CHEMBL185437 Ki 6.0 nM
O=S(=O)(c1ccccc1)C1(CCCN2CCC3CCCCC3C2)CCC1 CHEMBL206748 Ki 6.0 nM
C[C@@H]1NC(N)=Nc2cccc(Cl)c21 CHEMBL404372 Ki 6.0 nM
O=c1[nH]c2ccccc2n1CCCCCN1CCN(c2ccccc2)CC1 CHEMBL515780 Ki 6.0 nM
COc1ccccc1N1CCN(C(=O)NC(=N)NCc2cccc3ccccc23)CC1 CHEMBL557330 Ki 6.0 nM
CC(C)c1ccccc1OCCN1CC[C@@H](NS(=O)(=O)c2ccc(Cl)s2)C1 CHEMBL2159487 Ki 6.0 nM
NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1 CHEMBL3409035 Ki 6.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1cccc(Cl)c1 CHEMBL3740055 Ki 6.0 nM
O=S(=O)(NCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc(Cl)cc1 CHEMBL4103725 Ki 6.0 nM
COc1ccc(C2(C)NC(=O)N(CC(O)CN3CCN(c4ccccc4OC)CC3)C2=O)cc1 CHEMBL4163778 Ki 6.0 nM
CCOc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(c3ccccc3)C2=O)CC1 CHEMBL4176950 Ki 6.0 nM
CCn1cncc1-c1c[nH]c2ccc(I)cc12 CHEMBL4216263 Ki 6.0 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@H]1CCN1CCN(c2noc3ccccc23)CC1 CHEMBL4249640 Ki 6.0 nM
COc1ccc(/C=C2\NC(=O)N(CCCN3CCN(c4ccccc4OC)CC3)C2=O)cc1OC1CCCC1 CHEMBL4575904 Ki 6.0 nM
Cn1cncc1-c1c[nH]c2ccc(C(N)=O)cc12 CHEMBL4474827 Ki 6.0 nM
C=CCn1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 CHEMBL302766 Log Ki 6.026 nM
CN(C)C[C@H]1CC2c3ccccc3Sc3ccc(F)cc3[C@H]2O1 CHEMBL193639 Ki 6.2 nM
Cc1cccc(C)c1-c1cccc(CCN(C)C)c1 CHEMBL234881 Ki 6.2 nM
O=S(=O)(c1cccc2cccnc12)N(CCCN1CCN(c2cccc(C(F)(F)F)c2)CC1)CC1CC1 CHEMBL602878 IC50 6.3 nM
O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1cnc2ccccn12 CHEMBL3289963 Ki 6.3 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccs1 CHEMBL3290000 Ki 6.3 nM
C[C@@]12CN(c3ccccc3)c3ccccc3[C@@H]1CCN2 CHEMBL4457754 Ki 6.3 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21 CHEMBL19215 Log Ki 6.31 nM
CC(C)C[C@H]1C(=O)N[C@@H](Cc2ccccc2)[C@]2(O)O[C@@](C)(NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)C(=O)N12 CHEMBL2112882 Log Ki 6.31 nM
CCN(CC)C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL263881 Log Ki 6.31 nM
O=S(=O)(c1ccc2cc[nH]c2c1)N1CCC[C@@H]1CCN1CCC(c2cc3ccccc3[nH]2)CC1 CHEMBL331803 Log Ki 6.31 nM
CC1(C)CC(=O)N(CCCCN2Cc3ccccc3C2)C(=O)C1 CHEMBL3908870 pKi 6.31 nM
CCCNCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5081379 pKi 6.31 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL13816 Ki 6.4 nM
O=C1Nc2cccc3c2C1(CCCCN1CCc2sccc2C1)CCC3 CHEMBL314055 Log Ki 6.457 nM
CC(=O)n1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 CHEMBL71225 Log Ki 6.457 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc3c[nH]nc3c2)CC1 CHEMBL111922 Log Ki 6.457 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccc3[nH]cnc3c2)CC1 CHEMBL112876 Log Ki 6.457 nM
Cn1ccc2cc(S(=O)(=O)N[C@@H]3CCN(CCCc4noc5ccccc45)C3)ccc21 CHEMBL4759492 pKi 6.457 nM
CN(C)C[C@H]1C[C@@H]2c3ccccc3Sc3ccc(F)cc3[C@H]2O1 CHEMBL366164 Ki 6.5 nM
COCOc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccc(OC)cc3)CC2)cc1 CHEMBL3983496 Ki 6.5 nM
CN1CCc2cccc3c2C1Cc1cc2sc(N)nc2cc1-3 CHEMBL4633786 Ki 6.5 nM
Clc1cccc(-c2n[nH]cc2N2CCCNCC2)c1 CHEMBL4877603 Ki 6.5 nM
CCC1(CCCCN2CCN(c3ccccc3OC)CC2)C(=O)N(Cc2ccccc2)c2ccccc21 CHEMBL408451 Ki 6.57 nM
CCc1[nH]c2ccc(O)cc2c1CCN1CCN(c2cccc3ccccc23)CC1 CHEMBL3262395 Ki 6.6 nM
O=C1Nc2cc(F)ccc2C1CCCCN1CCN(c2cccc(Cl)c2)CC1 CHEMBL1836857 Ki 6.7 nM
O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1ccc2cc(Cl)ccc2c1 CHEMBL3289980 Ki 6.7 nM
Cc1nc(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)c(C)n1-c1ccccc1 CHEMBL3216758 IC50 6.8 nM
CCOc1ccccc1N1CCN(CCCCCn2cnc3ccccc3c2=O)CC1 CHEMBL3401488 Ki 6.88 nM
Cc1ccccc1-c1ccccc1N1CCNCC1 CHEMBL2164329 Ki 6.9 nM
COc1ccccc1N1CCN(Cc2cn(-c3cccc(C)c3C)c3ccccc23)CC1 CHEMBL3121422 Ki 6.9 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(Cl)c(Cl)c1 CHEMBL3289946 Ki 6.9 nM
O=C1c2ccccc2CCCN1CCN1CCC(N2C(=O)Cc3cc(F)ccc32)CC1 CHEMBL9446 Log Ki 6.918 nM
O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1cc2ccccc2o1 CHEMBL4764006 pKi 6.918 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2cc(F)c(Cl)cc21 CHEMBL260551 Ki 6.99 nM
FC(F)(F)c1ccc2ccn(CCN3CCCN4CCCCC4C3)c2c1 CHEMBL81276 Ki 7.0 nM
CC(C)(CCCN1CCCC(c2ccccc2)C1)S(=O)(=O)c1ccccc1 CHEMBL204269 Ki 7.0 nM
O=C1Cc2ccccc2N1CCCCN1CCc2ccccc2C1 CHEMBL445334 Ki 7.0 nM
O=c1[nH]c2ccccc2n1CCCCCN1CCN(c2ccc(Cl)cc2)CC1 CHEMBL515939 Ki 7.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2ccc(Cl)s2)C1 CHEMBL2159321 Ki 7.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)C1)c1ccc(F)c(F)c1 CHEMBL2159481 Ki 7.0 nM
O=[N+]([O-])c1ccc(-c2ccccc2N2CCNCC2)cc1 CHEMBL2164338 Ki 7.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc3ncccc23)CC1 CHEMBL3739680 Ki 7.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1ccc(F)cc1 CHEMBL3740913 Ki 7.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1cc(F)ccc1F CHEMBL3740801 Ki 7.0 nM
CN(C1CCN(CCOc2ccccc2-c2ccccc2)CC1)S(=O)(=O)c1cnn(C)c1 CHEMBL3747003 Ki 7.0 nM
CC(C)c1ccccc1OCCN1CC(NS(=O)(=O)c2ccc(F)cc2)C1 CHEMBL3758978 Ki 7.0 nM
CC1(c2ccc(Br)cc2)NC(=O)N(CC(O)CN2CCN(c3ccccc3C#N)CC2)C1=O CHEMBL4170613 Ki 7.0 nM
O=S(=O)(c1cccc2ncccc12)N1CCC[C@H]1CCN1CCN(c2noc3ccccc23)CC1 CHEMBL4249179 Ki 7.0 nM
O=S(=O)(c1cccc2ncccc12)N1CCC[C@H]1CCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4246202 Ki 7.0 nM
O=c1oc2ccccc2n1CCCCCCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4643450 Ki 7.0 nM
O=c1[nH]c2ccccc2n1CCCCCCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4638308 Ki 7.0 nM
Nc1nc(NCCc2c[nH]c3ccccc23)nc(NCCN2CCN(c3ccccc3)CC2)n1 CHEMBL5199820 Kb 7.0 nM
CN(C)C(=O)n1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 CHEMBL71959 Log Ki 7.079 nM
COc1cccc(OC)c1-c1cccc(N2CCNCC2)c1 CHEMBL2164343 Ki 7.1 nM
CCc1cc(-c2ccoc2)nc(N2CCN(C)CC2)n1 CHEMBL4208934 Ki 7.1 nM
CN(C)CCSc1cccc(C2(O)CCCCC2)n1 CHEMBL159143 Ki 7.2 nM
O=C1Nc2ccc(Cl)c3c2C1(CCCCN1CC=C(c2ccc(Cl)cc2)CC1)CCC3 CHEMBL348890 Ki 7.24 nM
O=S(=O)(N[C@H]1CCN(CCCc2noc3ccccc23)C1)c1cccc2ccccc12 CHEMBL4776225 pKi 7.244 nM
O=S(=O)(N[C@H]1CCN(CCCc2noc3ccccc23)C1)c1cc2ccccc2o1 CHEMBL4753094 pKi 7.244 nM
O=C(c1ccc(F)cc1)C1CCN(CCc2ccc(I)cc2)CC1 CHEMBL73979 Ki 7.32 nM
Cc1ccccc1-c1cccc(CCN)c1 CHEMBL234885 Ki 7.5 nM
COC(=O)c1sccc1NC(=O)CCCCN1CCN(c2ccccc2)CC1 CHEMBL4453552 Ki 7.54 nM
O=c1sc2ccccc2n1CCCCCCCN1CCN(c2ccccc2)CC1 CHEMBL3331389 Ki 7.58 nM
Cc1ccccc1-c1cccc(CCN(C)C)c1 CHEMBL395870 Ki 7.6 nM
CC1CCN(CCC[C@H]2CCCN2S(=O)(=O)c2ccccc2F)CC1 CHEMBL5173014 Ki 7.6 nM
CCC1(CCCCN2CCc3ccccc3C2)C(=O)Nc2ccccc21 CHEMBL407263 Ki 7.65 nM
C[C@@H]1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c21 CHEMBL256694 Ki 7.7 nM
COc1ccccc1N1CCN(CCCCCCCn2c(=O)oc3ccccc32)CC1 CHEMBL3331390 Ki 7.73 nM
O=C1c2ccc(Cl)cc2CC1CCCN1CCN(c2ccccn2)CC1 CHEMBL4862180 pKi 7.762 nM
COc1ccccc1N1CCN(CCCCn2c(=O)sc3ccccc32)CC1 CHEMBL3331257 Ki 7.77 nM
CN1C[C@@H](NS(=O)(=O)N(C)C)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21 CHEMBL12314 Log Ki 7.943 nM
CC(=O)c1ccccc1N1CCN(CCCCC23CCCc4cccc(c42)NC3=O)CC1 CHEMBL303166 Log Ki 7.943 nM
C[C@H]1Oc2c(cccc2N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)NC1=O CHEMBL196514 Log Ki 7.943 nM
Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C)C1 CHEMBL589390 pKi 7.943 nM
COc1ccc(C2NCCc3c2[nH]c2ccc(Cl)cc32)c(O)c1 CHEMBL5170784 Ki 7.98 nM
CC(Nc1nc(N)nc(NCCc2ccccc2)n1)c1ccc(F)cc1 CHEMBL183462 Ki 8.0 nM
CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 CHEMBL202780 Ki 8.0 nM
O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 CHEMBL204171 Ki 8.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(Cl)c2)CC1 CHEMBL3742251 Ki 8.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cc(F)ccc2F)CC1 CHEMBL3740235 Ki 8.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1cccc2ncccc12 CHEMBL3739582 Ki 8.0 nM
COc1ccc(-c2ccccc2N2CCN(CCCCCC(=O)NCc3ccc(C#N)cc3)CC2)cc1 CHEMBL3924375 Ki 8.0 nM
CC1(c2ccc(Cl)cc2)NC(=O)N(CC(O)CN2CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O CHEMBL4166804 Ki 8.0 nM
O=S(=O)(c1cncc2ccccc12)N1CCC[C@@H]1CCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 CHEMBL4246630 Ki 8.0 nM
Cn1cncc1-c1c[nH]c2ccc(I)cc12 CHEMBL4541526 Ki 8.0 nM
Nc1nc(NCCCCN2CCN(c3ccccc3)CC2)nc(NCCc2c[nH]c3ccccc23)n1 CHEMBL5189648 Ki 8.0 nM
CN(C(=O)CCCCCN1CCN(c2cccc3ccccc23)CC1)c1cccc(O)c1 CHEMBL3262432 Ki 8.1 nM
O=C1Nc2ccc(O)c3c2C1(CCCCN1CC=C(c2ccccc2)CC1)CCC3 CHEMBL422587 Log Ki 8.128 nM
COc1cccc2c1N=C(N)NC2C CHEMBL408152 Ki 8.2 nM
COc1ccccc1-c1cccc(N2CCNCC2)c1 CHEMBL2164328 Ki 8.2 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2ccc(Cl)cc21 CHEMBL411919 Ki 8.27 nM
O=C1Nc2cccc3c2C1(CCCN1CCc2ccccc2C1)CCC3 CHEMBL85814 Log Ki 8.318 nM
COc1ccccc1-c1cccc(CCN(C)C)c1 CHEMBL232792 Ki 8.4 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1806818 Kb 8.4 nM
CC1(CCCN2CCN(c3ccccn3)CC2)Cc2cc(Cl)ccc2C1=O CHEMBL4846823 Ki 8.4 nM
CCOc1ccccc1N1CCN(CCCCCn2c(C)nc3ccccc3c2=O)CC1 CHEMBL3884095 Ki 8.42 nM
COc1ccccc1N1CCN(CCCCCCCn2c(=O)sc3ccccc32)CC1 CHEMBL3331391 Ki 8.49 nM
O=C1c2ccccc2C(=O)N1CCCCN1CCc2ccccc2C1 CHEMBL273241 pKi 8.511 nM
CCCNCCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5093342 pKi 8.511 nM
COc1cccc(OC)c1-c1cccc(CCN(C)C)c1 CHEMBL232791 Ki 8.6 nM
COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 CHEMBL3326982 Ki 8.69 nM
CC1NC(N)=Nc2ccc(Cl)c(Cl)c21 CHEMBL273170 Ki 8.7 nM
COc1ccccc1N1CCN(Cc2cn(-c3ccccc3C)c3ccccc23)CC1 CHEMBL3121438 Ki 8.7 nM
NC(=O)Cn1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 CHEMBL70889 Log Ki 8.71 nM
O=C(c1ccc(F)cc1)C1CCN(CCc2cccc(I)c2)CC1 CHEMBL306478 Ki 8.76 nM
O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc(OC(F)(F)F)cc1 CHEMBL3289997 Ki 8.8 nM
Brc1ccc2ccn(CCN3CCCN(CC4CC4)CC3)c2c1 CHEMBL433134 Ki 9.0 nM
C[C@H](Nc1nc(N)nc(NCCc2ccccn2)n1)c1ccc(F)cc1 CHEMBL182418 Ki 9.0 nM
O=S(=O)(c1ccccc1)C1(CCCN2CCC(c3ccccc3)C2)CCC1 CHEMBL206563 Ki 9.0 nM
c1ccc2c3c([nH]c2c1)C(Cc1ccc2c(c1)OCO2)NCC3 CHEMBL328476 Ki 9.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2)C1)c1ccc(F)cc1 CHEMBL2159479 Ki 9.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)C1)c1cc(F)ccc1F CHEMBL2159483 Ki 9.0 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1cc2ccc(Cl)cc2s1 CHEMBL3289960 Ki 9.0 nM
COc1ccccc1N1CCN(CCCCC(=O)NC2CCCc3ccccc32)CC1 CHEMBL222864 Ki 9.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)CCCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCOCC1 CHEMBL3409049 Ki 9.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)CCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCCCC1 CHEMBL3409047 Ki 9.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCOCC1 CHEMBL3409046 Ki 9.0 nM
CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(F)c2)CC1 CHEMBL3740054 Ki 9.0 nM
O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1cncc2ccccc12 CHEMBL3741445 Ki 9.0 nM
CC(C)c1ccccc1OCCN1CCC(N(C)S(=O)(=O)c2ccccc2)CC1 CHEMBL3747052 Ki 9.0 nM
CC(C)c1cccc(OCCN2C3CCC2CC(NS(=O)(=O)c2ccc(F)c(F)c2)C3)c1 CHEMBL3759262 Ki 9.0 nM
O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc(F)cc1 CHEMBL4088249 Ki 9.0 nM
CC1(c2ccc(Cl)cc2)NC(=O)N(CC(O)CN2CCN(c3ccccc3C#N)CC2)C1=O CHEMBL4174055 Ki 9.0 nM
O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCCCN1CCN(c2nsc3ccccc23)CC1 CHEMBL4641609 Ki 9.0 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2cc(F)c(Cl)cc21 CHEMBL261009 Ki 9.07 nM
O=c1[nH]c(SCCCN2CCN(Cc3ccccc3)CC2)nc2c1sc1ccccc12 CHEMBL4586787 Ki 9.08 nM
Cn1c(=O)cnn(CCCCN2CCN(c3cccc4ccc(O[11CH3])cc34)CC2)c1=O CHEMBL199824 Ki 9.1 nM
Cc1ccc(OC2CCN(CCN3CCCc4ccccc4C3=O)CC2)cc1 CHEMBL9770 Log Ki 9.12 nM
CCNCc1ccc(Cl)c(-c2ccccc2OC)c1 CHEMBL5074880 Ki 9.3 nM
O=C1c2ccccc2CCCN1CCN1CCC(n2c(=O)oc3cc(F)ccc32)CC1 CHEMBL9250 Log Ki 9.333 nM
O=c1[nH]c(CCCCN2CCN(c3cccc(Cl)c3)CC2)nc2c1sc1ccccc12 CHEMBL4441943 Ki 9.42 nM
CCC1(CCCCN2CCN(c3cccc(Cl)c3)CC2)C(=O)Nc2c(Cl)cc(Cl)cc21 CHEMBL259009 Ki 9.46 nM
CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2c(Cl)cc(Cl)cc21 CHEMBL260870 Ki 9.5 nM
O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(F)c(Cl)c1 CHEMBL3289947 Ki 9.5 nM
O=C(CCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)NCc1ccc(OCCCN2CCOCC2)cc1 CHEMBL3906408 Ki 9.5 nM
CN(C)[C@H]1CCc2c(cccc2-c2ccccc2)C1 CHEMBL4648289 Ki 9.5 nM
COc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1 CHEMBL224820 pA2 9.55 nM
[11CH3]N1C(=O)C2(CCCCN3CCc4sccc4C3)CCCc3cccc1c32 CHEMBL2311141 Ki 9.7 nM
[11CH3]N1C(=O)C2(CCCCCN3CCc4sccc4C3)CCCc3cccc1c32 CHEMBL2413451 Ki 9.7 nM
CN1C(=O)C2(CCCCN3CCc4sccc4C3)CCCc3cccc1c32 CHEMBL85602 Ki 9.7 nM
Cn1ccc2c(S(=O)(=O)N[C@@H]3CCN(CCCc4noc5ccccc45)C3)cccc21 CHEMBL4742856 pKi 9.772 nM
CN1CCc2cccc3c2[C@H]1Cc1cccc(-c2ccccc2)c1-3 CHEMBL25924 Ki 9.78 nM
O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1cc2ccccc2s1 CHEMBL3289958 Ki 9.9 nM
O=S(=O)(NCCCN1CCN(c2noc3ccccc23)CC1)c1ccc(F)c(Cl)c1 CHEMBL3289971 Ki 9.9 nM
CN1CCc2cccc3c2C1Cc1ccc2nc(N)sc2c1-3 CHEMBL4641502 Ki 9.9 nM