COC[C@H](NC(=O)C(F)(F)c1cccc(Cl)c1)C(=O)N1C[C@H](S(=O)(=O)Cc2ccc(OC)cc2)C[C@H]1C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C CHEMBL4589967 IC50 0.262 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1cccc(Cl)c1)Oc1cc(Cl)cc(C#N)c1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4554156 IC50 0.293 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(Cl)c(C#N)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4542635 IC50 0.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4471645 IC50 0.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4533165 IC50 0.3 nM
COC[C@H](NC(=O)c1cccc(Cl)c1)C(=O)N1C[C@H](S(=O)(=O)Cc2ccc(OC)cc2)C[C@H]1C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C CHEMBL4471714 IC50 0.351 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2cccc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4540590 IC50 0.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(F)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4461666 IC50 0.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)Cc2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4585025 IC50 0.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2cc(Cl)ccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4588306 IC50 0.4 nM
COc1ccc([C@H](NC(=O)C(Cc2cccc(Cl)c2)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4551033 IC50 0.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)c3ccccn3)cc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085441 IC50 0.4 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(F)c2)Oc2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4472162 IC50 0.461 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](C)NC(=O)C(F)(F)c3cccc(F)c3)C2)cc1 CHEMBL4472070 IC50 0.471 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)OC(C)(C)C)cc2)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5074107 IC50 0.49 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2cccc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4446982 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4453892 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cc(Cl)ccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4462378 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4557186 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4441695 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4542403 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4520550 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4576875 IC50 0.5 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1ccccc1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4447637 IC50 0.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085715 IC50 0.5 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCCN3CCOCC3)C(C)C)N(C(=O)[C@H](Cc3cccc(F)c3)NC(=O)c3cccc(Cl)c3)C2)cc1 CHEMBL4517216 IC50 0.538 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CNC(=O)OC(C)(C)C)cc3)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4451038 IC50 0.55 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(Cl)c(Cl)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4462973 IC50 0.574 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](COC(C)(C)C)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4447513 IC50 0.579 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4530656 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)C2(c3cccc(Cl)c3)CC2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4459683 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cc(Cl)cc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4468950 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4533961 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4524175 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(C#N)c(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4581447 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)[C@H](c2ccc(Cl)cc2)C(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5080837 IC50 0.6 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5083134 IC50 0.602 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075130 IC50 0.62 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089492 IC50 0.62 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](S(=O)(=O)Cc2ccccc2)CN1C(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1ccccn1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4587944 IC50 0.667 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(F)c2)Oc2cccc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4450427 IC50 0.686 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@@H](Cc3cccc(Cl)c3)Oc3cc(Cl)cc(Cl)c3)C2)cc1 CHEMBL4449164 IC50 0.694 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)Cc2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5074725 IC50 0.695 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C2CCC2)cc1 CHEMBL4444635 IC50 0.7 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2ccc(Cl)c(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087160 IC50 0.7 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076217 IC50 0.71 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(Cl)c2)Oc2cc(Cl)cc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4436099 IC50 0.711 nM
COc1ccc([C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075529 IC50 0.76 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(C)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4535102 IC50 0.781 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4565155 IC50 0.8 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccccn1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4576315 IC50 0.8 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088052 IC50 0.8 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(Cl)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4526287 IC50 0.804 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090493 IC50 0.83 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](C)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4553646 IC50 0.838 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(Cl)c2)Oc2cncc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4454953 IC50 0.838 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCCN3CCOCC3)C(C)C)N(C(=O)[C@H](Cc3cccc(F)c3)NC(=O)C3(c4ccccc4F)CCCC3)C2)cc1 CHEMBL4534289 IC50 0.871 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](S(=O)(=O)Cc2ccccc2)CN1C(=O)[C@@H](Cc1cccc(Cl)c1)Oc1cncc(Cl)c1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4454613 IC50 0.876 nM
COc1ccc(CO[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(Cl)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4447004 IC50 0.889 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@@H](Cc3cccc(Cl)c3)Oc3cncc(Cl)c3)C2)cc1 CHEMBL4471786 IC50 0.897 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C2CCC2)cc1 CHEMBL4462243 IC50 0.9 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4568952 IC50 0.9 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4591831 IC50 0.9 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3ccc(Cl)cc3)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092521 IC50 0.9 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)[C@@H](c2ccc(Cl)cc2)C(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079564 IC50 0.9 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(Cl)c2)Oc2cc(Cl)cc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4534638 IC50 0.917 nM
COc1ccc(CS[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@@H](Cc3cccc(Cl)c3)Oc3cc(Cl)cc(Cl)c3)C2)cc1 CHEMBL4535101 IC50 0.933 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CNC(=O)OC(C)(C)C)cc3)NC(=O)c3cccc(Cl)c3)C2)cc1 CHEMBL4582422 IC50 0.95 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccc(Cl)c(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085309 IC50 0.97 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2ccc(Cl)c(Cl)c2)Oc2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4469142 IC50 0.985 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(CNC(=O)OC(C)(C)C)c(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073350 IC50 1.0 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CNC(=O)OC(C)(C)C)cc3)NC(=O)C(F)(F)c3ccccc3C(F)(F)F)C2)cc1 CHEMBL4531423 IC50 1.05 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(F)c2)Oc2cc(C#N)cc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4550175 IC50 1.05 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](CO)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4547683 IC50 1.06 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(Cl)c2)Oc2cc(C#N)cc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4522207 IC50 1.088 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4520809 IC50 1.1 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(OCC(=O)OC(C)(C)C)c2)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5071227 IC50 1.1 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(OCC(=O)OC(C)(C)C)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081385 IC50 1.1 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccccc2C#N)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090925 IC50 1.1 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCNC(=O)c2cnccn2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5094342 IC50 1.1 nM
COc1ccc(CS[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(Cl)c(Cl)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4457383 IC50 1.135 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)OC(C)(C)C)cc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079542 IC50 1.2 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093404 IC50 1.2 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)C2(c3cccc(Cl)c3)CC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5072605 IC50 1.2 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)C(c2cccc(C(F)(F)F)c2)C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073793 IC50 1.2 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](C)NC(=O)c3cccc(Cl)c3)C2)cc1 CHEMBL4459774 IC50 1.25 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CNC(=O)OC(C)(C)C)cc3)NC(=O)C3(c4ccc(Cl)cc4)CCCC3)C2)cc1 CHEMBL4536408 IC50 1.27 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(Cl)c2)Oc2cc(C)cc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4581362 IC50 1.28 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4453477 IC50 1.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)C2(c3ccc(Cl)cc3)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090245 IC50 1.3 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(C#N)c3)NC(=O)c3ccc(Cl)cn3)C2)cc1 CHEMBL4585453 IC50 1.308 nM
COC[C@H](NC(=O)C(F)(F)c1ccccc1C(F)(F)F)C(=O)N1C[C@H](S(=O)(=O)Cc2ccc(OC)cc2)C[C@H]1C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C CHEMBL4452462 IC50 1.33 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(C#N)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4571615 IC50 1.333 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088948 IC50 1.4 nM
COc1ccc([C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076292 IC50 1.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093226 IC50 1.4 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2cccc(Cl)c2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087021 IC50 1.4 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccccc2C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087575 IC50 1.4 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C2(c3ccc(Cl)cc3)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089894 IC50 1.4 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)Oc1cc(Cl)cc(Cl)c1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4514919 IC50 1.47 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C2CC2)cc1 CHEMBL4467136 IC50 1.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(Cl)c(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4584930 IC50 1.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)COc2ccc(OCC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093762 IC50 1.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(CN)c(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075278 IC50 1.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccccc2OC(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5080697 IC50 1.5 nM
COC[C@H](NC(=O)C(F)(F)c1cccc(Cl)c1)C(=O)N1C[C@H](S(=O)(=O)Cc2ccc(OC)cc2)C[C@H]1C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C CHEMBL4441935 IC50 1.54 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](OCc2ccccc2)CN1C(=O)[C@@H](Cc1ccccc1)Oc1cc(Cl)cc(Cl)c1)C(=O)C(F)(F)F CHEMBL4437302 IC50 1.55 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C2CCC2)cc1 CHEMBL4438347 IC50 1.6 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccc(Cl)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092239 IC50 1.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)C2(c3ccccc3)CC2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4473497 IC50 1.7 nM
COc1ccc([C@H](NC(=O)[C@H](COCc2ccccc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087778 IC50 1.7 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(Br)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086316 IC50 1.7 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5078465 IC50 1.703 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)Oc2cc(Cl)cc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4449141 IC50 1.75 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(C#N)c2)Oc2cc(Cl)cc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4565414 IC50 1.76 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5091486 IC50 1.8 nM
COc1ccc([C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076131 IC50 1.8 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(c2ccc(Cl)cc2)C(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088663 IC50 1.8 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079892 IC50 1.82 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079914 IC50 1.9 nM
COc1ccc([C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5083056 IC50 1.9 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)c2cccc(C(F)(F)F)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5091137 IC50 1.9 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCNC(=O)c2ccccn2)NC(=O)C(F)(F)c2ccc(Cl)c(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089605 IC50 1.9 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CN)cc3)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4585871 IC50 1.99 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C2CC2)cc1 CHEMBL4435648 IC50 2.0 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](SCCc2ccccc2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4549578 IC50 2.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)C(F)(F)c1cccc(Cl)c1)c1ccc(OCC(=O)OC(C)(C)C)cc1)C(=O)C(F)(F)F CHEMBL5078252 IC50 2.0 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)N(C(=O)[C@H](C)NC(=O)C(F)(F)c3cc(Cl)ccc3Cl)C2)cc1 CHEMBL4516846 IC50 2.08 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2ccccc2)Oc2cc(Cl)cc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4462488 IC50 2.085 nM
Cc1cccc(C[C@H](NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)c2ccccc2)c1 CHEMBL4443046 IC50 2.1 nM
COc1ccc([C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5080063 IC50 2.1 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](OCc2ccccc2)CN1C(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1ccccn1)C(=O)C(F)(F)F CHEMBL4461827 IC50 2.19 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1ccccn1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4453669 IC50 2.3 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cc(Cl)ccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4514775 IC50 2.3 nM
COc1ccc([C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5078768 IC50 2.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)Cc2ccc(CNC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076620 IC50 2.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2cccc(OCC(=O)NCC(=O)OC(C)(C)C)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084404 IC50 2.3 nM
COc1ccc([C@H](NC(=O)[C@H](CC#N)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076185 IC50 2.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4466280 IC50 2.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(OCC(=O)OC(C)(C)C)n2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075450 IC50 2.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)Cc2ccc(CN)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089088 IC50 2.4 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccccn1)C(=O)C(F)(F)F CHEMBL5077417 IC50 2.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088932 IC50 2.5 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2ccccc2OC(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5077594 IC50 2.5 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C2CC2)cc1 CHEMBL4540825 IC50 2.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(F)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5091601 IC50 2.6 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccccn1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5081749 IC50 2.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)C(F)(F)c2ccccc2C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5080407 IC50 2.8 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cc(Cl)cc(Cl)c2)Oc2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4564396 IC50 2.83 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](C)NC(=O)C(F)(F)c3ccccc3C(F)(F)F)C2)cc1 CHEMBL4456156 IC50 2.89 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3cccc(Cl)c3)CCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073212 IC50 2.9 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OC(F)F)cn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4531627 IC50 3.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccnc2)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090497 IC50 3.1 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCNC(=O)c2cncnc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085573 IC50 3.1 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)OC(C)(C)C)cn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090988 IC50 3.2 nM
COc1ccc([C@H](NC(=O)[C@H](COC(F)(F)F)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075369 IC50 3.2 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](CO)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4444232 IC50 3.21 nM
COC[C@H](NC(=O)C1(C(F)(F)F)CCCC1)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5076658 IC50 3.3 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CN)cc3)NC(=O)C3(c4ccc(Cl)cc4)CCCC3)C2)cc1 CHEMBL4591813 IC50 3.35 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2cccc(F)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084221 IC50 3.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(OCC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093548 IC50 3.6 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2cc(Cl)ccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5077600 IC50 3.7 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2cc(Cl)ccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082275 IC50 3.9 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCN)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087732 IC50 3.9 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@H](c2ccccc2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4520468 IC50 4.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)[C@@H](c2ccc(Cl)cc2)C2CCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088126 IC50 4.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)C(c2cccc(C(F)(F)F)c2)C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073783 IC50 4.0 nM
COc1ccc([C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084016 IC50 4.0 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(Cl)c3)NC(=O)c3ccccn3)C2)cc1 CHEMBL4466528 IC50 4.12 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4475600 IC50 4.3 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082680 IC50 4.3 nM
COc1ccc([C@H](NC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085434 IC50 4.3 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](C)NC(=O)C(F)(F)c3cccc(Cl)c3)C2)cc1 CHEMBL4568529 IC50 4.36 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(c2ccc(Cl)cc2)C2CC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084310 IC50 4.6 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)[C@H](c2ccc(Cl)cc2)C2CCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5072037 IC50 4.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)[C@H](c2ccc(Cl)cc2)C(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085658 IC50 4.7 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccccc2C#N)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084451 IC50 4.9 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](NC(=O)Cc2cccnc2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4466722 IC50 5.0 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](SC(C)(C)C)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4438886 IC50 5.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)OC(C)(C)C)cc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088113 IC50 5.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3c(F)cccc3Cl)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084716 IC50 5.1 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](OCc2ccccc2)CN1C(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cnccn1)C(=O)C(F)(F)F CHEMBL4552701 IC50 5.11 nM
COc1ccc([C@H](NC(=O)[C@H](CCCNC(=O)c2ccccn2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081795 IC50 5.4 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)C(F)(F)c1cccc(Cl)c1)c1ccc(OCC(=O)O)cc1)C(=O)C(F)(F)F CHEMBL5075862 IC50 5.6 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4545700 IC50 5.62 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)[C@@H](c2ccc(Cl)cc2)C(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085504 IC50 5.8 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073038 IC50 5.9 nM
CCOc1ccccc1C(F)(F)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5091025 IC50 5.9 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)[C@H](c2ccc(Cl)cc2)C(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086899 IC50 5.9 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CN)cc3)NC(=O)C(F)(F)c3ccccc3C(F)(F)F)C2)cc1 CHEMBL4592558 IC50 6.01 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)OC(C)(C)C)cc2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092857 IC50 6.1 nM
CCc1ccccc1C(F)(F)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5079230 IC50 6.1 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCNC(=O)c2ccccn2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085685 IC50 6.1 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4447678 IC50 6.4 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)Oc1cc(Cl)cc(Cl)c1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4535243 IC50 6.59 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1cnccn1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5090327 IC50 6.6 nM
COc1cccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ncccc2C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1 CHEMBL5090195 IC50 6.6 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)C(CC23CCC(CC2)C3)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4562363 IC50 6.65 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(N(C)C)cn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4441908 IC50 6.8 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1ccc(OC(F)F)cn1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4583912 IC50 6.8 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CNC(=O)OC(C)(C)C)cc2)NC(=O)C2(C(F)(F)F)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5070253 IC50 6.8 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](N2CCCCC2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4461228 IC50 7.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccn(CC(=O)OC(C)(C)C)c(=O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5077777 IC50 7.1 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(O)(c2ccc(Cl)c(Cl)c2)C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5094094 IC50 7.1 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccccc1)Oc1cc(Cl)cc(Cl)c1)c1ccccc1)C(=O)C(F)(F)C(=O)NCCN1CCOCC1 CHEMBL4460259 IC50 7.115 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089534 IC50 7.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093409 IC50 7.3 nM
COc1ccc(CS[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)COc3cc(Cl)cc(Cl)c3)C2)cc1 CHEMBL4542523 IC50 7.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(C)(C)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081934 IC50 7.6 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cnccn1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5079722 IC50 7.7 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(CN)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092895 IC50 7.9 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3ccccc3F)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5077623 IC50 7.9 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5078243 IC50 8.0 nM
COc1ccc([C@H](NC(=O)[C@H](CC#N)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089698 IC50 8.0 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079724 IC50 8.1 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1ccncc1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4550102 IC50 8.3 nM
COc1ccc([C@H](NC(=O)[C@H](COC(F)(F)F)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082025 IC50 8.5 nM
COc1ccc([C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5094129 IC50 8.5 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cnccn1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4513305 IC50 8.6 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(OCC(=O)NCC(=O)OC(C)(C)C)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082810 IC50 8.7 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](OCc2ccccc2)CN1C(=O)COc1cc(Cl)cc(Cl)c1)C(=O)C(F)(F)F CHEMBL4466195 IC50 8.95 nM
COc1ccc([C@H](NC(=O)[C@@H](Cc2cccc(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4561913 IC50 9.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4550677 IC50 9.08 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cncnc1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4462273 IC50 9.3 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5083740 IC50 9.5 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccnc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082076 IC50 9.8 nM
NC(=O)C(=O)C1(NC(=O)[C@@H]2C[C@H](n3nncc3C3(O)COC3)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)CCCCC1 CHEMBL4525588 IC50 9.82 nM
CC(C)[C@H](NC(=O)C1C=C(c2ccccc2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4446596 IC50 10.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(OC(F)(F)F)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092460 IC50 10.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)C(CC2CC3(CCC3)C2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4540076 IC50 10.4 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(O)(c2cccc(Cl)c2)C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087294 IC50 10.4 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3cccc(Cl)c3)NC(=O)c3cnccn3)C2)cc1 CHEMBL4476072 IC50 10.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(O)(c2cccc(C(F)(F)F)c2)C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092969 IC50 10.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3ccccc3)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089717 IC50 10.7 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@H](NC(=O)CCc2ccccc2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4569500 IC50 11.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCC3(CC3)CC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4525283 IC50 11.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)c2cccc(C(F)(F)F)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086117 IC50 11.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)C2(C(F)(F)F)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5083661 IC50 11.4 nM
COC[C@H](NC(=O)C(F)(F)c1cccc(Cl)c1)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5084348 IC50 12.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)C(=O)C(F)(F)F CHEMBL5083468 IC50 12.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(N3CCOCC3)cn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4584692 IC50 12.4 nM
NC(=O)C(=O)C1(NC(=O)[C@@H]2C[C@@H](N3CCCCC3)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)CCCCC1 CHEMBL4539208 IC50 12.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5070652 IC50 13.0 nM
COc1ccc([C@H](NC(=O)[C@H](CCCCN)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076420 IC50 13.3 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)[C@H](Cc3ccc(CN)cc3)NC(=O)c3cccc(Cl)c3)C2)cc1 CHEMBL4592994 IC50 13.5 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2ccccc2OC)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073040 IC50 13.5 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2cnc3ccccc3c2)C1 CHEMBL4578579 IC50 13.8 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@H](c2ccccc2)CN1C(=O)[C@@H](CC1CCCCC1)N[C@H](c1ccc2ccccc2c1)C(F)(F)F)B(O)O CHEMBL4438287 IC50 14.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1cnccn1)C(=O)C(F)(F)F CHEMBL5089873 IC50 14.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(=O)n(CC(=O)OC(C)(C)C)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5074645 IC50 14.0 nM
COc1cccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1 CHEMBL5090928 IC50 14.0 nM
COC[C@H](NS(=O)(=O)c1ccc(Cl)s1)C(=O)N1C[C@H](S(=O)(=O)Cc2ccc(OC)cc2)C[C@H]1C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C CHEMBL4567543 IC50 14.8 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL4583235 IC50 15.6 nM
CC(C)[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4570179 IC50 16.0 nM
COC[C@H](NC(=O)c1cccc(Cl)c1)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5089918 IC50 16.0 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4571697 IC50 16.1 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(CN)cc2)NC(=O)C(c2ccc(Cl)cc2)C2CCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084130 IC50 16.4 nM
NC(=O)C(=O)C1(NC(=O)[C@@H]2C[C@H](n3nncc3CNS(=O)(=O)C3CC3)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)CCCCC1 CHEMBL4538235 IC50 17.2 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccccc2OC)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082877 IC50 17.2 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2cccc(F)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079323 IC50 17.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)CNC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4438484 IC50 17.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)(F)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092418 IC50 18.0 nM
CS(=O)(=O)Cc1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4548414 IC50 18.1 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(c2cccc(C(F)(F)F)c2)C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086722 IC50 19.1 nM
COc1ccc([C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5070091 IC50 19.2 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](OCc2ccccc2)CN1C(=O)CCc1ccc(Cl)c(Cl)c1)C(=O)C(F)(F)F CHEMBL4444523 IC50 19.6 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(C(F)(F)F)CCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5079050 IC50 19.6 nM
CC(C)(O)c1cn([C@H]2C[C@@H](C(=O)NC3(C(=O)C(N)=O)CCCCC3)N(C(=O)[C@@H](CC3CCCCC3)NC(=O)c3ccc4ccccc4c3)C2)nn1 CHEMBL4575689 IC50 20.1 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3cccc(Cl)c3)CC2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4558074 IC50 20.2 nM
CCOc1ccccc1C(F)(F)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5085605 IC50 20.3 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cc(Cl)ccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081231 IC50 21.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1cncnc1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5081277 IC50 21.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccccc2C(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5077226 IC50 21.5 nM
COCCS(=O)(=O)c1ccc(C(=O)N[C@H](CC2CCCCC2)C(=O)N2C[C@@H](n3nncc3C(C)(C)O)C[C@H]2C(=O)NC2(C(=O)C(N)=O)CCCCC2)cc1 CHEMBL4570772 IC50 21.6 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C2(c3cccc(Cl)c3)CC2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)[C@@H](C)O)cc1 CHEMBL4439705 IC50 22.2 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CC3(CCC3)C2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4529555 IC50 22.3 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3cccc(Cl)c3)OCCO2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076107 IC50 22.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(C(F)(F)F)CCCCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093752 IC50 22.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(C(F)(F)F)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090777 IC50 24.0 nM
NC(=O)C(=O)C1(NC(=O)[C@@H]2C[C@H](n3cc(C4(O)COC4)nn3)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)CCCCC1 CHEMBL4535592 IC50 24.4 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C(F)(F)c2ccccc2C#N)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082467 IC50 25.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)C(CC23CCC(CC2)C3)NC(=O)c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL4558523 IC50 25.2 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccc(Br)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087647 IC50 26.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cnccn1)C(=O)C(F)(F)F CHEMBL5088614 IC50 27.0 nM
O=C(NCCCC[C@H](NC(=O)[C@@H]1C[C@@H](N2CCCCC2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O)NC1CCCCC1 CHEMBL4573080 IC50 28.0 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)c2ccc(Cl)s2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084770 IC50 28.0 nM
CCC(C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1)c1ccccc1 CHEMBL5084618 IC50 28.5 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)C2(c3cccc(Cl)c3)CC2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4518486 IC50 28.7 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073186 IC50 29.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)O)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081919 IC50 29.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2cccc(OCC(=O)NCC(=O)O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075115 IC50 29.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)C(CC2CC3(CCC3)C2)NC(=O)c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL4550151 IC50 30.5 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(C)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076362 IC50 31.1 nM
COC[C@H](NC(=O)C1(F)CCCC1)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1ccc(OC)cc1 CHEMBL5083377 IC50 31.8 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccnc2)NC(=O)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5078711 IC50 32.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)Cc2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075664 IC50 32.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cncnc1)C(=O)C(F)(F)F CHEMBL5092572 IC50 32.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)CNC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089678 IC50 32.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccccc2OC(F)(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5076221 IC50 34.8 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)c1ccc(Cl)s1)c1ccc(OCC(=O)O)cc1)C(=O)C(F)(F)F CHEMBL5074693 IC50 35.9 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)C1(c2cccc(Cl)c2)CC1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F CHEMBL4456940 IC50 36.3 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2cccc3cn[nH]c23)C1 CHEMBL4541355 IC50 36.8 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)C1 CHEMBL4545920 IC50 37.4 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)CNC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4467753 IC50 37.5 nM
COc1ccc([C@H](NC(=O)[C@H](CC(N)=O)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092764 IC50 37.8 nM
COc1cccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cnccc2C)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1 CHEMBL5079886 IC50 38.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)CNC(=O)c2ccccn2)C(=O)N[C@H](C(=O)CC(F)(F)F)C(C)C)cc1 CHEMBL5086084 IC50 38.0 nM
CC1(C)CCC(NC(=O)[C@@H]2C[C@H](n3nncc3C(C)(C)O)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)(C(=O)C(N)=O)CC1 CHEMBL4592605 IC50 38.5 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3nccn3c2)C1 CHEMBL4589410 IC50 40.3 nM
CCOc1cccc(C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c2ccc(OC)cc2)c1 CHEMBL5091767 IC50 41.4 nM
COc1ccc([C@H](NC(=O)[C@H](CCCN)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081250 IC50 43.3 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C(F)c2ccccc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088411 IC50 44.0 nM
CS(=O)(=O)c1ccc(C(=O)N[C@H](CC2CCCCC2)C(=O)N2C[C@@H](n3nncc3C3(O)COC3)C[C@H]2C(=O)NC2(C(=O)C(N)=O)CCCCC2)cc1 CHEMBL4536465 IC50 46.0 nM
COc1cccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cnccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)c1 CHEMBL5090798 IC50 46.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4483330 IC50 47.2 nM
O=C(NCCCCC[C@H](NC(=O)[C@@H]1C[C@@H](N2CCCCC2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O)NC1CCCCC1 CHEMBL4450424 IC50 49.0 nM
O=C(N[C@H](CC1CCCCC1)C(=O)N1C[C@H](N2CCCCC2)C[C@H]1C(=O)N[C@@H](CCCCn1cc(-c2ccccc2)nn1)B(O)O)c1ccc2ccccc2c1 CHEMBL4457420 IC50 49.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(C(F)(F)F)CCC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5073327 IC50 54.6 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccccc2OC(F)F)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5083233 IC50 54.8 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(S(=O)(=O)CC(N)=O)cc2)C1 CHEMBL4539366 IC50 55.3 nM
COc1ccc(CS(=O)(=O)[C@@H]2C[C@@H](C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)N(C(=O)COc3cc(Cl)cc(Cl)c3)C2)cc1 CHEMBL4448766 IC50 55.35 nM
O=C(NCCC[C@H](NC(=O)[C@@H]1C[C@@H](N2CCCCC2)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O)NC1CCCCC1 CHEMBL4574688 IC50 57.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)O)cc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5078619 IC50 57.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)CCc2cccnc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086157 IC50 59.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(C#N)cc2)C1 CHEMBL4539239 IC50 59.6 nM
CC(C)[C@H](NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)B(O)O CHEMBL4474054 IC50 60.0 nM
COc1ccc([C@H](NC(=O)[C@H](COCc2ccccc2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088880 IC50 61.0 nM
COCCOCCOCCOCCNC(=O)c1ccc2cc(C(=O)N[C@H](CC3CCCCC3)C(=O)N3C[C@@H](n4nncc4C(C)(C)O)C[C@H]3C(=O)NC3(C(=O)C(N)=O)CCCCC3)ccc2c1 CHEMBL4521345 IC50 63.1 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085947 IC50 65.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)O)cc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087592 IC50 66.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)O)cc2)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4471168 IC50 68.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CNC(=O)OCc2ccccc2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4539918 IC50 68.0 nM
COc1ccc([C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5078631 IC50 69.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(OC)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093747 IC50 71.2 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)O)cc2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4538055 IC50 77.3 nM
CC1(C)CCC(NC(=O)[C@@H]2C[C@H](n3nncc3C(C)(C)O)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(S(C)(=O)=O)cc2)(C(=O)C(N)=O)CC1 CHEMBL4575007 IC50 78.2 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)O)cc2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)C(=O)NCC(F)(F)F)C(C)C)cc1 CHEMBL4473901 IC50 79.5 nM
NC(=O)C(=O)C1(NC(=O)[C@@H]2C[C@H](n3nncc3CC(=O)O)CN2C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)CCCCC1 CHEMBL4555708 IC50 81.1 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1cccc(Cl)c1)NC(=O)c1ccccn1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5089687 IC50 82.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1cccc(Cl)c1)NC(=O)c1cnccn1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5085764 IC50 82.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)C2(c3cccc(Cl)c3)CC2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087225 IC50 86.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(OCC(=O)NCC(=O)O)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082496 IC50 86.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(OCC(=O)O)c2)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089353 IC50 89.0 nM
CS(=O)(=O)c1ccc(C(=O)N[C@H](CC2CCCCC2)C(=O)N2C[C@@H](n3cc(C4(O)COC4)nn3)C[C@H]2C(=O)NC2(C(=O)C(N)=O)CCCCC2)cc1 CHEMBL4585989 IC50 90.1 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccc(Cl)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075543 IC50 90.2 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2ccc(OCC(=O)O)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088378 IC50 98.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(=O)NCC(F)(F)F)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4580371 IC50 110.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088969 IC50 110.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)Cc2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086017 IC50 110.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)COc2ccc(OCC(=O)O)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5091086 IC50 110.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(OCC(=O)NCC(=O)O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075433 IC50 120.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)C1CCN(C)C1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5089339 IC50 130.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(B(O)O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4516474 IC50 138.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)O)cn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5092255 IC50 140.0 nM
CS(=O)(=O)Cc1cn([C@H]2C[C@@H](C(=O)NC3(C(=O)C(N)=O)CCCCC3)N(C(=O)[C@@H](CC3CCCCC3)NC(=O)c3ccc(S(C)(=O)=O)cc3)C2)nn1 CHEMBL4587246 IC50 142.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(=O)NCC(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4563536 IC50 144.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(=O)NCS(C)(=O)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4525317 IC50 146.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(OCC(=O)O)c2)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5094312 IC50 150.0 nM
COc1ccc([C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)C(F)(F)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075070 IC50 150.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(OCC(=O)O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5088146 IC50 150.0 nM
CS(=O)(=O)Cc1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL4573227 IC50 155.0 nM
CC(C)(O)c1cn([C@H]2C[C@@H](C(=O)NC3(C(=O)C(N)=O)CCCCC3)N(C(=O)[C@@H](CC3CCCCC3)NC(=O)c3ccc(S(C)(=O)=O)cc3)C2)nn1 CHEMBL4543736 IC50 157.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)O)cc2)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5090688 IC50 160.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)c2cccc(OCC(=O)O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5075999 IC50 170.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CC3(CCC3)C2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL4522737 IC50 181.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)Cc2ccc(CN)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089269 IC50 190.0 nM
CO[C@@H]1[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C[C@H]1n1nncc1C(C)(C)O CHEMBL4566146 IC50 199.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5087820 IC50 210.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)C1CCN(C)CC1)C(=O)C(F)(F)F CHEMBL5090609 IC50 220.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1cccc(Cl)c1)NC(=O)c1cncnc1)c1ccccc1)C(=O)C(F)(F)F CHEMBL5083365 IC50 220.0 nM
CC(CC1CCCCC1)(NC(=O)c1ccc2ccccc2c1)C(=O)N1C[C@@H](n2nncc2C(C)(C)O)C[C@H]1C(=O)NC1(C(=O)C(N)=O)CCCCC1 CHEMBL4554493 IC50 223.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4524723 IC50 261.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccn(CC(=O)O)c(=O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5081402 IC50 290.0 nM
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)c1ccc2cc(C(=O)N[C@H](CC3CCCCC3)C(=O)N3C[C@@H](n4nncc4C(C)(C)O)C[C@H]3C(=O)NC3(C(=O)C(N)=O)CCCCC3)ccc2c1 CHEMBL4533027 IC50 303.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2ccc(OCC(=O)O)cc2)NC(=O)C(F)(F)c2ccccc2Cl)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5074468 IC50 310.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(OCC(=O)NCC(=O)O)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5093212 IC50 310.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2ccc(=O)n(CC(=O)O)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5085389 IC50 350.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2cccc(C#N)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5091059 IC50 364.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1cccc(Cl)c1)NC(=O)c1cncnc1)C(=O)C(F)(F)F CHEMBL5082568 IC50 400.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1cccc(Cl)c1)NC(=O)c1cnccn1)C(=O)C(F)(F)F CHEMBL5083577 IC50 420.0 nM
COc1ccc([C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)c2cccc(Cl)c2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5084090 IC50 450.0 nM
CC(CC1CCCCC1)(NC(=O)c1ccc(S(C)(=O)=O)cc1)C(=O)N1C[C@@H](n2nncc2C(C)(C)O)C[C@H]1C(=O)NC1(C(=O)C(N)=O)CCCCC1 CHEMBL4533622 IC50 523.0 nM
COc1ccc([C@H](NC(=O)[C@H](C)NC(=O)c2ccc(CN)cc2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5089624 IC50 570.0 nM
CC(C)C[C@H](NC(=O)CCCCCNC(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](C(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1 CHEMBL5277138 IC50 590.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)[C@@H](CNS(C)(=O)=O)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4570157 IC50 606.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(=O)NC3COC3)CCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4539667 IC50 620.0 nM
COc1ccc([C@H](NC(=O)[C@H](CO)NC(=O)c2ccccn2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5086562 IC50 630.0 nM
O=C(N[C@H](CC1CCCCC1)C(=O)N1C[C@H](N2CCCCC2)C[C@H]1C(=O)N[C@@H](CCCCN1CC2(CSC2)C1)B(O)O)c1ccc2ccccc2c1 CHEMBL4516368 IC50 660.0 nM
CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCCCC2)N(C(=O)[C@@H](CC2CCCCC2)NC(=O)c2ccc3ccccc3c2)C1 CHEMBL4589328 IC50 675.0 nM
COc1ccc([C@H](NC(=O)[C@H](Cc2cccc(Cl)c2)NC(=O)c2cccc(OCC(=O)O)n2)C(=O)N[C@H](C(=O)C(F)(F)F)C(C)C)cc1 CHEMBL5082584 IC50 810.0 nM