NCCCCCc1c[nH]cn1 CHEMBL417096 Potency 0.0251 nM
O=C(Nc1cc([N+](=O)[O-])ccc1Cl)c1ccc2c(c1)OCO2 CHEMBL1426021 Potency 0.0251 nM
Cc1n[nH]c2c1C(c1ccccc1)C1=C(O)CC(C)(C)CC1=N2 CHEMBL1399505 Potency 0.0316 nM
Cc1ccc(Sc2ncnc3onc(C)c23)c(C)c1 CHEMBL1538342 Potency 0.0355 nM
CCOC(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCN(C)C3 CHEMBL1417371 Potency 0.0447 nM
O=C(O)Cc1ccc(-c2ccccc2)cc1 CHEMBL413965 Potency 0.0501 nM
CCCNc1ccc(C(=O)OCC)cc1[N+](=O)[O-] CHEMBL1549532 Potency 0.2 nM
COCCCNS(=O)(=O)c1ccc2[nH]c(O)nc2c1 CHEMBL1565490 Potency 0.2 nM
c1ccc2c(c1)CCCN2Cc1nnc2n1CCCCC2 CHEMBL1422059 Potency 0.4 nM
COC(=O)c1ccc(Cc2ccccc2)o1 CHEMBL1303176 Potency 0.4 nM
Clc1ccccc1C1=Nn2c(nnc2-c2ccncc2)SC1 CHEMBL1341124 Potency 0.4 nM
CCOC(=O)N1CCC(N2CCCC(CO)(Cc3cccc(OC)c3)C2)CC1 CHEMBL1438034 Potency 0.6 nM
C=C(C)C(=O)Nc1cccc(C2=NOC3(C2)C[C@@H](C(N)=O)N(C(=O)CC(c2ccccc2)c2ccccc2)C3)c1 CHEMBL1518604 Potency 0.6 nM
CC(=O)c1ccc(NC(=O)Nc2ncn(Cc3cccc(C)c3)n2)cc1 CHEMBL1471818 Potency 0.6 nM
CN(C)CCCN(Cc1ccccc1)C(S)=Nc1cccc(C(F)(F)F)c1 CHEMBL1464588 Potency 0.6 nM
Cc1csc(NC(=O)CSc2nnc(-c3ccncc3)n2C)n1 CHEMBL1320163 Potency 0.8 nM
CCOC(=O)N1CCN(C(=O)c2ccc(CS(=O)(=O)c3c(Cl)cccc3Cl)o2)CC1 CHEMBL1371387 Potency 0.9 nM
Cn1cc(C2=C(c3ccc(Cl)cc3Cl)C(=O)NC2=O)c2ccccc21 CHEMBL102714 Potency 0.9 nM
COC(=O)C1C(=O)c2c([nH]c(C(=O)OC3CCCCCC3)c2C)CC1C CHEMBL1307475 Potency 1.0 nM
O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccccc2N1 CHEMBL296586 Potency 1.0 nM
O=C(C[n+]1ccc(Cc2ccccc2)cc1)Nc1ccc([N+](=O)[O-])cc1Cl CHEMBL1460806 Potency 1.1 nM
O=C(OCC(F)(F)F)[C@H](O)[C@@H](O)C(=O)OCC(F)(F)F CHEMBL1314987 Potency 1.3 nM
Cn1cc2cc(-c3ccc(-c4cnc(N5CCNC(CO)C5)nn4)c(O)c3)cc(F)c2n1 CHEMBL4875017 IC50 1.6 nM
Cn1nc2cc(-c3ccc(-c4cnc(N5CCN[C@@H](C6CC6)C5)nn4)c(O)c3)cnc2n1 CHEMBL4878942 IC50 1.7 nM
Oc1cc(-c2c[nH]nc2F)ccc1-c1cnc(N2CCN[C@@H](C3CC3)C2)nn1 CHEMBL4863336 IC50 2.1 nM
CC1CN(c2ncc(-c3ccc(-c4cc(F)c5nn(C)cc5c4)cc3O)nn2)CCN1 CHEMBL4847156 IC50 2.1 nM
CCCC(=O)Nc1ccc(C#Cc2ccccc2)cc1 CHEMBL1374893 Potency 2.2 nM
Nc1c(S(=O)(=O)c2cccs2)c2nc3ccccc3nc2n1CC1CCCO1 CHEMBL1485295 Potency 2.2 nM
CCC1CN(c2ncc(-c3ccc(-c4cc(F)c5nc(C)cn5c4)cc3O)nn2)CCN1 CHEMBL4867927 IC50 2.2 nM
Cc1cn2cc(-c3ccc(-c4cnc(N5CCN[C@@H](C(C)C)C5)nn4)c(O)c3)ncc2n1 CHEMBL4859053 IC50 2.3 nM
Cc1[nH]c2ccccc2c1C(=O)COC(=O)C1CCC(=O)N1 CHEMBL1531569 Potency 2.5 nM
COc1cc2c(cc1O)CCN[C@@]21CS[C@H]2c3c(OC(C)=O)c(C)c4c(c3C(COC1=O)N1C2C2c3c(cc(C)c(OC)c3O)CC([C@@H]1O)N2C)OCO4 CHEMBL1522262 Potency 2.5 nM
O=C(Nc1ccc(CSc2ccccc2)cc1)c1ccc(CN2CCOCC2)cc1 CHEMBL1427457 Potency 2.8 nM
CN1C(=O)C(O)(C2COC(C)(C)CC2=O)c2ccccc21 CHEMBL1366201 Potency 2.8 nM
Cc1cccc(NC(=O)CSc2nnc(-c3ccccc3C)o2)c1 CHEMBL1453691 Potency 2.8 nM
Cc1ccc(-n2nnc3c(=O)n(CC(=O)OCc4ccccc4)cnc32)cc1 CHEMBL1313778 Potency 2.8 nM
N#CC1=C(SCc2ccccc2)NC(=O)CC1c1ccccc1 CHEMBL1373983 Potency 3.2 nM
COCCNC(=O)CN(C(=O)CCC(=O)Nc1ccccn1)c1ccccc1F CHEMBL1442568 Potency 4.5 nM
Cc1csc(NC(=O)[C@@H](NC(=O)c2ccccc2)C(C)C)n1 CHEMBL1543244 Potency 4.5 nM
Cc1ccc(-n2ncc3c(NCc4ccco4)ncnc32)cc1C CHEMBL1321101 Potency 5.0 nM
O=C(COC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3)NC1CCS(=O)(=O)C1 CHEMBL1527550 Potency 6.3 nM
CCOC(=O)c1sc(NC(=O)c2ccc(S(=O)(=O)N3CCCCCC3)cc2)nc1-c1ccccc1 CHEMBL1580359 Potency 6.3 nM
CCCc1cc(O)nc(SCC(=O)c2cc(C)n(CCOC)c2C)n1 CHEMBL1406095 Potency 7.1 nM
CCN1CCC(c2cc3c(F)cc(-c4cc(C)c5nc(C)cn5n4)cc3nn2)CC1 CHEMBL5179682 IC50 8.0 nM
Cc1ccccc1CNC(=O)c1ccccc1C(=O)O CHEMBL1601713 Potency 8.9 nM
CCOP(=O)(Cc1cc(C(=O)CC)c(C)o1)OCC CHEMBL1602321 Potency 10.0 nM
Cc1cc(C)c(C(=O)COC(=O)c2cc([N+](=O)[O-])ccc2NCCO)cc1C CHEMBL1509005 Potency 14.1 nM
N=C1/C(=C/c2cccn2Cc2ccc(F)cc2)C(=O)N=C2SC=CN12 CHEMBL1433254 Potency 14.1 nM
CCCn1nnnc1SCC(=O)NCc1ccc2c(c1)OCO2 CHEMBL1427501 Potency 15.8 nM
Cc1ccc(Nc2nc(-c3ccc(O)cc3O)cs2)nc1 CHEMBL1400505 Potency 15.8 nM
CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C=O)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1 CHEMBL90555 Potency 17.8 nM
Cc1cc(-c2ccc(/N=N/c3c(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(N)c4c3O)c(C)c2)ccc1/N=N/c1c(S(=O)(=O)O)cc2cc(S(=O)(=O)O)cc(N)c2c1O CHEMBL1089641 Potency 20.0 nM
CCCn1c(=O)c2c(nc3n2CCN3Cc2ccco2)n(C)c1=O CHEMBL1380650 Potency 25.1 nM
Fc1cccc2sc(Nc3nnc(-c4ccco4)o3)nc12 CHEMBL1461196 Potency 25.1 nM
Cn1cc(C=C2C(=O)CC(C)(C)CC2=O)c2ccccc21 CHEMBL1573026 Potency 25.1 nM
Cc1ccc(OCC(=O)N2CCN(C(=O)c3ccncc3)CC2)cc1 CHEMBL1516718 Potency 28.2 nM
O=C(CCCc1cccs1)Nc1nc2c(s1)CCCC2 CHEMBL1444064 Potency 28.2 nM
Cc1cc(-c2ccccc2)nc(N/N=C/c2ccc([N+](=O)[O-])cc2)n1 CHEMBL3199116 Potency 28.2 nM
COC(=O)/C=C/c1ccc(OC(=O)OC)c(OC(=O)OC)c1 CHEMBL1587526 Potency 28.2 nM
COc1ccc(S(=O)(=O)N2CCCC2C(=O)n2nc(C)cc2C)cc1 CHEMBL1413448 Potency 28.2 nM
Cc1cc(O)ccc1N/C=C/c1onc(C)c1[N+](=O)[O-] CHEMBL1322179 Potency 28.2 nM
O=C(Nc1ccc(F)cc1)c1ccc2[nH]cnc2c1 CHEMBL1437881 Potency 31.6 nM
CCCCCn1c(CN2CCN(C)CC2)nc2c1c(=O)n(C)c(=O)n2C CHEMBL1359386 Potency 31.6 nM
COc1ccc(-c2nc(-c3ccccc3)no2)c(OC)c1 CHEMBL473735 Potency 31.6 nM
Cc1sc2ncnc(OCC(=O)N3CCN(S(=O)(=O)c4ccccc4)CC3)c2c1C CHEMBL1455655 Potency 31.6 nM
CC1CC(OP(=O)(S)c2ccc(N(C)C)cc2NC(=O)c2cccs2)CC(C)(C)C1 CHEMBL1600349 Potency 31.6 nM
COc1ccc(F)c(-c2nc(CN3CCC(c4ccccc4)CC3)c(C)o2)c1 CHEMBL1535191 Potency 31.6 nM
CS(=O)(=O)NNC(=O)CN1C(=O)C2C3C=CC(C3)C2C1=O CHEMBL1612884 Potency 31.6 nM
COC(=O)c1nc(O)c2ccccc2c1O CHEMBL1523832 Potency 31.6 nM
O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21 CHEMBL1057 Potency 31.6 nM
Cc1c2oc3c(C)ccc(C(=O)N[C@@H]4C(=O)N[C@H](C(C)C)C(=O)N5CCC[C@H]5C(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)O[C@@H]4C)c3nc-2c(C(=O)N[C@@H]2C(=O)N[C@H](C(C)C)C(=O)N3CCC[C@H]3C(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)O[C@@H]2C)c(N)c1=O CHEMBL1554 Potency 31.6 nM
CCOC(=O)c1ccc(NC(=O)C2CC(=O)Nc3nc4ccccc4n32)cc1 CHEMBL1588585 Potency 31.6 nM
COc1cccc(NC(=S)N2CCN(Cc3ccccc3)CC2)c1 CHEMBL1328442 Potency 31.6 nM
CC1=C(C(=O)N(C)CCC#N)C2(CCCCC2)OC1=O CHEMBL1402500 Potency 31.6 nM
CC1Cc2ccccc2N1C(=O)CN(C)S(=O)(=O)c1cccc2cccnc12 CHEMBL1375195 Potency 31.6 nM
c1ccc(CSc2ccc(-c3cccs3)nn2)nc1 CHEMBL1306451 Potency 31.6 nM
Cc1ccc(C(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)s1 CHEMBL1499477 Potency 31.6 nM
COC(=O)c1ccc(CN2C(=O)NC3(CCCCC3)C2=O)cc1 CHEMBL1374484 Potency 31.6 nM
O=C(COC(=O)C1CC1)c1c[nH]c2ccccc12 CHEMBL1305281 Potency 31.6 nM
Cc1noc(C)c1C(=O)N(CC(=O)NC1CCCC1)Cc1ccccc1F CHEMBL1462196 Potency 31.6 nM
O=c1c2cnn(-c3ccc(F)cc3)c2ncn1Cc1ccc(F)cc1 CHEMBL1479719 Potency 31.6 nM
CN(C)Cc1c(-c2ccc(Cl)cc2)nc2ccccn12 CHEMBL1363582 Potency 31.6 nM
O=C(Nc1nc2ccc(F)cc2s1)c1cccc(S(=O)(=O)N2CCc3ccccc32)c1 CHEMBL1465704 Potency 31.6 nM
Cc1nc2ccc(NC(=O)c3ccc(Cl)c([N+](=O)[O-])c3)cc2s1 CHEMBL1472331 Potency 31.6 nM
O=C(O)c1cccnc1SC1CC(=O)N(c2cccc(C(F)(F)F)c2)C1=O CHEMBL1444186 Potency 35.5 nM
O=C(CN1C(=O)COc2ccccc21)NCCN1CCC(Cc2ccccc2)CC1 CHEMBL1373861 Potency 35.5 nM
CC(OC(=O)CCc1nc(O)c2ccccc2n1)C(=O)c1ccc(Br)cc1 CHEMBL1455162 Potency 35.5 nM
CN1CCN([S+]([O-])C23CC4CC(CC(C4)C2)C3)CC1 CHEMBL1324594 Potency 35.5 nM
Cc1ccc(-n2c(SCC(=O)Nc3nccs3)nc3c(c2=O)SCC3)cc1 CHEMBL1534287 Potency 35.5 nM
CC1(C)CC(Oc2ccc(-c3ccc(-c4ccnc(O)c4)cc3O)nn2)CC(C)(C)N1 CHEMBL5195936 IC50 40.0 nM
Cc1ccc(O)c(NC(=O)COc2cc(C)ccc2C)c1 CHEMBL1371372 Potency 50.1 nM
Cn1nnnc1Sc1ncnc2scc(-c3cccc4ccccc34)c12 CHEMBL1325058 Potency 50.1 nM
CC(C)(C#CCN1CCCC1)OCCC#N CHEMBL1517900 Potency 70.8 nM
COc1ccc(-c2nc3c(c4nnc(SC(C)C(=O)Nc5ccccc5)n24)COC(C)(C)C3)cc1 CHEMBL1499273 Potency 79.4 nM
Cc1cc(C)n(CCC(=O)N/N=C/c2c(O)ccc3ccccc23)n1 CHEMBL3190786 Potency 79.4 nM
CCN1CCC(c2cc(C)c3nc(-c4ccc5nn(C)cc5c4)cc(=O)n3c2)CC1 CHEMBL5175104 IC50 80.0 nM
CN(C)S(=O)(=O)c1cccc(NC(=O)c2cncc(Br)c2)c1 CHEMBL1576080 Potency 89.1 nM
CCN1CCN(CCC(=O)Nc2ccc(Br)cc2)CC1 CHEMBL1418853 Potency 89.1 nM
CCOC(=O)c1ccccc1NC(=O)c1c(F)c(F)c(F)c(F)c1F CHEMBL1564871 Potency 89.1 nM
COc1ccc(NC(=O)C2CCN(Cc3cnn(-c4ccccc4)c3-n3cccc3)CC2)cc1OC CHEMBL1320011 Potency 89.1 nM
COCCCNC(=O)CSc1ccc(Cl)cc1 CHEMBL1319914 Potency 89.1 nM
Cc1cc(N2C(=O)CC(N3CCC(n4c(O)nc5ccccc54)CC3)C2=O)no1 CHEMBL1362388 Potency 89.1 nM
CC(C)Cc1cc(C(=O)NCc2cccnc2)no1 CHEMBL1338752 Potency 89.1 nM
COc1cc(/C=N/NC(=O)Cn2ccc(C(F)(F)F)n2)cc(OC)c1OC CHEMBL3197610 Potency 89.1 nM
C=CCNC(=O)Cn1nc(-c2ccccc2)ccc1=O CHEMBL1352224 Potency 89.1 nM
C/C=C(/C)C(=O)O[C@@H]1c2cc3c(c(OC)c2-c2c(cc(OC)c(OC)c2OC)[C@@H](OC(C)=O)[C@@H](C)[C@H]1C)OCO3 CHEMBL1564371 Potency 89.1 nM
Cc1ccc(-c2cc(C(=O)NCc3ccco3)no2)cc1 CHEMBL1351040 Potency 89.1 nM
COC(=O)c1cn(NC(=O)COc2ccc(Cl)cc2)c(=O)c2ccccc12 CHEMBL1327434 Potency 89.1 nM
OC(CN1c2ccccc2Sc2ccccc21)Cn1nnc2ccccc21 CHEMBL1588229 Potency 89.1 nM
CCn1c(S)nnc1CCNC(=O)c1cccs1 CHEMBL1326829 Potency 89.1 nM
Cc1ccc(C2C(C(=O)c3sc(C)nc3C)=C(O)C(=O)N2CCN(C)C)o1 CHEMBL1509348 Potency 89.1 nM
CCOC(=O)C1=C(Cc2ccc(C)cc2)C(=O)c2ccccc2C1=O CHEMBL1327627 Potency 89.1 nM
O=C(NCc1ccccc1C(F)(F)F)C1CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)=NO1 CHEMBL1429342 Potency 89.1 nM
C=CCn1c(COc2cccc3cccnc23)nnc1SCC(=O)OC CHEMBL1569411 Potency 89.1 nM
O=C(Nc1cccc2cccnc12)c1cccnc1 CHEMBL1412716 Potency 89.1 nM
O=C(NCc1ccco1)C(Cc1ccccc1)NS(=O)(=O)c1cccc2nsnc12 CHEMBL1548620 Potency 89.1 nM
CN1CCN(c2oc(COc3ccc(-c4ccccc4)cc3)nc2C#N)CC1 CHEMBL1312038 Potency 89.1 nM
Cc1cccc2cc(C(c3nnnn3Cc3ccccc3)N3CCN(C)CC3)c(O)nc12 CHEMBL1550403 Potency 89.1 nM
CC(=O)N1CCN(c2ccc(NC(=S)NC(=O)c3ccc(C)c([N+](=O)[O-])c3)cc2)CC1 CHEMBL1576979 Potency 89.1 nM
CCCNC(=O)C1CC(c2ccc(C(F)(F)F)cc2)=NO1 CHEMBL1331505 Potency 89.1 nM
Cn1cc(-c2nc3ccccc3[nH]2)c2ccccc21 CHEMBL1500773 Potency 89.1 nM
Cc1ccccc1C(=O)Nc1ccc2c(C#N)c3nc4ccccc4nc3n2c1 CHEMBL1384217 Potency 89.1 nM
CCOC(=O)C1CCCN(C(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)C1 CHEMBL1527283 Potency 89.1 nM
Cc1ccc(S(=O)(=O)N(C)CC(=O)OCc2nnc(-c3ccccc3)o2)cc1 CHEMBL1421115 Potency 89.1 nM
O=C1NC(c2ccccc2)C(C(=O)c2cccs2)=C1O CHEMBL1383004 Potency 89.1 nM
Cc1ccc(-c2c(C#N)c(N)nc3c2CCCCCC3)o1 CHEMBL1362821 Potency 89.1 nM
Cc1ccc(C)c(CN2CCCNC2=O)c1 CHEMBL1541581 Potency 89.1 nM
O=C(c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1303401 Potency 89.1 nM
C=CCn1c(CNC(=O)c2cccs2)nnc1SCC(=O)Nc1ccc(C(=O)O)cc1 CHEMBL1343417 Potency 89.1 nM
O=c1c2ccccc2nc(SCc2ccccc2)n1CC1CCCO1 CHEMBL1415081 Potency 89.1 nM
CC1CCCC(C2(O)C(=O)Nc3ccccc32)C1=O CHEMBL1442086 Potency 89.1 nM
C=C(C)C(=O)Nc1cccc(C2=NOC3(C2)C[C@@H](C(N)=O)N(C(=O)[C@H]2CCC(=O)N2)C3)c1 CHEMBL1503011 Potency 89.1 nM
COc1ccc(NC(=O)CCn2nc(C)cc2C)cc1 CHEMBL1424676 Potency 89.1 nM
COc1ccc(NC(=O)c2ccc(CN(c3cc(Cl)ccc3C)S(=O)(=O)c3ccccc3)cc2)cc1OC CHEMBL1375926 Potency 89.1 nM
Cc1ccc(C(=O)CNc2ccc(Br)cc2)cc1 CHEMBL1589540 Potency 89.1 nM