CNC(=O)c1cc2c(Oc3ccc(C(F)(F)F)cc3)cncc2s1 CHEMBL119501 IC50 1.0 nM
NC(=O)c1cc2c(Oc3ccc(COC4CCCCO4)cc3)cncc2s1 CHEMBL118113 IC50 1.4 nM
N#Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL117198 IC50 2.0 nM
C=Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL119733 IC50 2.0 nM
CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1 CHEMBL117279 IC50 2.0 nM
CS(=O)(=O)c1cccc(C[C@H](NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc4ccoc4c2)C3)C(=O)O)c1 CHEMBL2048028 IC50 2.98 nM
NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1 CHEMBL116070 IC50 3.0 nM
CNC(=O)c1cc2c(Oc3ccc(C(=O)CC(C)(O)c4ccc(Oc5cncc6sc(C(=O)NC)cc56)cc4)cc3)cncc2s1 CHEMBL119335 IC50 3.8 nM
COCCOCCOCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL117746 IC50 4.0 nM
CNC(=O)c1cc2c(Oc3ccc(-n4cccn4)cc3)cncc2s1 CHEMBL119039 IC50 4.0 nM
NC(=O)c1cc2c(Oc3ccc(I)cc3)cncc2s1 CHEMBL116152 IC50 4.0 nM
CNC(=O)c1cc2c(Oc3ccc(-c4ccco4)cc3)cncc2s1 CHEMBL118034 IC50 5.0 nM
CNC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1 CHEMBL326271 IC50 5.0 nM
NC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 CHEMBL326120 IC50 5.0 nM
CNC(=O)c1cc2c(Oc3ccc(-c4cccs4)cc3)cncc2s1 CHEMBL117894 IC50 6.0 nM
CNC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 CHEMBL325184 IC50 6.0 nM
COCCOCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL117668 IC50 6.0 nM
CNC(=O)c1cc2c(Oc3ccc(COCCOC)cc3)cncc2s1 CHEMBL331584 IC50 8.0 nM
Cc1ccc(Sc2cncc3sc(C(N)=O)cc23)cc1C CHEMBL267125 IC50 8.0 nM
NC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 CHEMBL118518 IC50 9.0 nM
CNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 CHEMBL118074 IC50 10.0 nM
NC(=O)c1cc2c(Oc3ccc(Cl)c(F)c3)cncc2s1 CHEMBL118886 IC50 10.0 nM
NC(=O)c1cc2c(Sc3ccc(Br)cc3)cncc2s1 CHEMBL266198 IC50 10.0 nM
NC(=O)c1cc2c(Oc3ccc(C(F)(F)F)cc3)cncc2s1 CHEMBL116089 IC50 13.0 nM
COCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL119183 IC50 16.0 nM
NC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)N4CCOCC4)cc3)cncc2s1 CHEMBL419046 IC50 16.0 nM
CNC(=O)c1cc2c(Oc3ccc(COC)cc3)cncc2s1 CHEMBL326771 IC50 17.0 nM
CNC(=O)c1cc2c(Oc3ccc(C#N)cc3)cncc2s1 CHEMBL115971 IC50 18.0 nM
CCOC(=O)c1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL116307 IC50 18.0 nM
CCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL119732 IC50 20.0 nM
Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL117453 IC50 20.0 nM
CNC(=O)c1cc2c(Oc3ccc(-c4noc(C(F)(F)F)n4)cc3)cncc2s1 CHEMBL116454 IC50 22.0 nM
NC(=O)c1cc2c(Oc3ccc(CO)cc3)cncc2s1 CHEMBL118022 IC50 23.0 nM
Cc1ccc(Sc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL267678 IC50 25.0 nM
CNC(=O)c1cc2c(Oc3ccc(-c4ccccc4)cc3)cncc2s1 CHEMBL115637 IC50 25.0 nM
NC(=O)c1cc2c(Sc3ccccc3)cncc2s1 CHEMBL267456 IC50 25.0 nM
CCOCCOCCOCC(F)(F)c1ccc(Oc2cncc3sc(C(=O)NC)cc23)cc1 CHEMBL115431 IC50 26.0 nM
CNC(=O)c1cc2c(Oc3ccc(CO)cc3)cncc2s1 CHEMBL115966 IC50 31.0 nM
NC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCCN4CCOCC4)cc3)cncc2s1 CHEMBL325651 IC50 32.0 nM
Cc1ccc(Sc2cncc3sc(C(=O)NN)cc23)cc1 CHEMBL269598 IC50 32.0 nM
CCNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 CHEMBL119091 IC50 34.0 nM
CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3ccccc3C(C)C)c([N+](=O)[O-])c2)CC1 CHEMBL19677 IC50 35.0 nM
NC(=O)c1cc2c(Sc3ccc(Cl)c(Cl)c3)cncc2s1 CHEMBL6612 IC50 37.0 nM
NC(=O)c1cc2c(Sc3ccc(C(F)(F)F)cc3)cncc2s1 CHEMBL6542 IC50 39.0 nM
CNC(=O)c1cc2c(Oc3ccc(C(C)=O)cc3)cncc2s1 CHEMBL118299 IC50 40.0 nM
Cc1ccccc1Sc1cncc2sc(C(N)=O)cc12 CHEMBL6278 IC50 40.0 nM
NC(=O)c1cc2c(Oc3ccc(N)cc3)cncc2s1 CHEMBL117936 IC50 42.0 nM
CNC(=O)c1cc2c(Oc3ccc(C4(CO)CC4)cc3)cncc2s1 CHEMBL118089 IC50 46.0 nM
CC(C)c1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL324158 IC50 47.0 nM
NC(=O)c1cc2c(Sc3ccc(Cl)cc3)cncc2s1 CHEMBL268567 IC50 48.0 nM
CNC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCCN4CCOCC4)cc3)cncc2s1 CHEMBL325033 IC50 53.0 nM
CNC(=O)c1cc2c(Oc3ccc(OC(F)(F)F)cc3)cncc2s1 CHEMBL118300 IC50 53.0 nM
Cc1ccc(Sc2cncc3sc(C(N)=O)cc23)c(C)c1 CHEMBL6830 IC50 54.0 nM
CNC(=O)c1cc2c(Oc3ccc(C(=N)NO)cc3)cncc2s1 CHEMBL116363 IC50 59.0 nM
CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3ccc(Cl)cc3Cl)c([N+](=O)[O-])c2)CC1 CHEMBL129869 IC50 63.0 nM
O=C(NCCO)c1cc2c(Oc3ccc(Br)cc3)cncc2s1 CHEMBL119886 IC50 75.0 nM
CNC(=O)c1cc2c(Oc3ccc(N4CCOCC4)cc3)cncc2s1 CHEMBL117093 IC50 79.0 nM
Cc1cc(Oc2cncc3sc(C(N)=O)cc23)ccc1Cl CHEMBL115815 IC50 82.0 nM
C/C(=N\O)c1cc2c(Sc3ccc(C)cc3)cncc2s1 CHEMBL262570 IC50 85.0 nM
CON(C)C(=O)c1cc2c(Sc3ccc(C)cc3)cncc2s1 CHEMBL6517 IC50 99.0 nM
CCc1ccccc1Sc1ccc(/C=C/C(=O)N2CCN(C(C)=O)CC2)cc1[N+](=O)[O-] CHEMBL130486 IC50 100.0 nM
CC(C)(C)c1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL117571 IC50 110.0 nM
NC(=O)c1cc2c(Oc3cccc(Br)c3)cncc2s1 CHEMBL119815 IC50 110.0 nM
NC(=O)c1cc2c(Oc3ccc(C(=O)N(C(=O)NC4CCCCC4)C4CCCCC4)cc3)cncc2s1 CHEMBL117671 IC50 116.0 nM
CNC(=O)c1cc2c(Oc3ccc(NCCCN4CCN(C)CC4)cc3)cncc2s1 CHEMBL117292 IC50 120.0 nM
CNC(=O)c1cc2c(Oc3ccc(N4CCN(C)CC4)cc3)cncc2s1 CHEMBL326712 IC50 120.0 nM
NC(=O)c1cc2c(Oc3ccccc3)cncc2s1 CHEMBL331662 IC50 120.0 nM
CCOCCOCCOCC1(c2ccc(Oc3cncc4sc(C(=O)NC)cc34)cc2)CC1 CHEMBL115960 IC50 130.0 nM
O=C(/C=C/c1ccc(Sc2ccc(Cl)cc2Cl)c([N+](=O)[O-])c1)NCCCN1CCCC1=O CHEMBL422802 IC50 140.0 nM
COc1ccc(Sc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL263081 IC50 140.0 nM
COc1ccc2sc(C(N)=O)c(OC(C)C)c2c1 CHEMBL6248 IC50 140.0 nM
Cc1cccc(Sc2cncc3sc(C(N)=O)cc23)c1 CHEMBL269497 IC50 140.0 nM
Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1Cl CHEMBL115981 IC50 150.0 nM
CC(=O)Nc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL434222 IC50 150.0 nM
NC(=O)c1cc2c(Oc3ccc(F)cc3)cncc2s1 CHEMBL115742 IC50 160.0 nM
CNC(=O)c1cc2c(Oc3ccc(-n4cncn4)cc3)cncc2s1 CHEMBL119705 IC50 160.0 nM
Cc1ccc(Sc2cncc3sc(C(=N)S)cc23)cc1 CHEMBL266429 IC50 160.0 nM
CONC(=O)c1cc2c(Sc3ccc(C)cc3)cncc2s1 CHEMBL269075 IC50 170.0 nM
CN(C)C(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 CHEMBL324133 IC50 180.0 nM
O=C(/C=C/c1ccc(Sc2ccccc2/C=C/C(=O)N2CCOCC2)c(Cl)c1)N1CCOCC1 CHEMBL338870 IC50 190.0 nM
CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3ccc(Cl)cc3Cl)c(Cl)c2)CC1 CHEMBL101416 IC50 240.0 nM
CC(=O)c1cc2c(Sc3ccc(C)cc3)cncc2s1 CHEMBL266708 IC50 250.0 nM
CC(=O)NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4170909 IC50 270.0 nM
CS(=O)(=O)NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4162980 IC50 270.0 nM
CS(=O)(=O)NCC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4174346 IC50 270.0 nM
CS(=O)(=O)NCCC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4166434 IC50 270.0 nM
O=S(=O)(NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)C(F)(F)F CHEMBL4164084 IC50 270.0 nM
O=S(=O)(NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)c1ccccc1 CHEMBL4174739 IC50 270.0 nM
NS(=O)(=O)NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4167533 IC50 270.0 nM
CNS(=O)(=O)NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4159616 IC50 270.0 nM
CN(C)S(=O)(=O)NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4166036 IC50 270.0 nM
O=S(=O)(NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)N1CCCCC1 CHEMBL4176645 IC50 270.0 nM
O=S(=O)(NC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)N1CCOCC1 CHEMBL4163423 IC50 270.0 nM
CC(=O)N1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4171320 IC50 270.0 nM
CS(=O)(=O)N1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4166876 IC50 270.0 nM
NS(=O)(=O)N1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4174777 IC50 270.0 nM
CN(C)S(=O)(=O)N1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4175184 IC50 270.0 nM
c1cnc2c(n1)Nc1cc(CN3CCC3)ccc1S2 CHEMBL4168474 IC50 270.0 nM
c1cnc2c(n1)Nc1cc(CN3CCCCC3)ccc1S2 CHEMBL4165398 IC50 270.0 nM
c1cnc2c(n1)Nc1cc(CN3CCCCCC3)ccc1S2 CHEMBL4170693 IC50 270.0 nM
c1cnc2c(n1)Nc1cc(CN3CCCCCCC3)ccc1S2 CHEMBL4160056 IC50 270.0 nM
NC(=O)C1CCCN(Cc2ccc3c(c2)Nc2nccnc2S3)C1 CHEMBL4159218 IC50 270.0 nM
NC(=O)C1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4170462 IC50 270.0 nM
NC(=O)c1cc2c(Oc3ccc(Cl)cc3Br)cncc2s1 CHEMBL119599 IC50 300.0 nM
CNC(=O)c1cc2c(Oc3ccc(C(F)(F)CO)cc3)cncc2s1 CHEMBL324824 IC50 320.0 nM
O=C(NCCO)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 CHEMBL119523 IC50 340.0 nM
CNC(=O)c1cc2c(Oc3ccc(-c4cncn4C)cc3)cncc2s1 CHEMBL331055 IC50 360.0 nM
O=C(/C=C/c1ccc(Sc2ccccc2CN2CCN(Cc3ccc4c(c3)OCO4)CC2)c(Cl)c1)N1CCOCC1 CHEMBL262940 IC50 360.0 nM
NC(=O)c1cc2c(Cl)cncc2s1 CHEMBL6257 IC50 360.0 nM
O=C(O)C1CC2(CCN(Cc3ccc4c(c3)Nc3nccnc3S4)CC2)C1 CHEMBL4160058 IC50 420.0 nM
O=C(O)CC1CC2(CCN(Cc3ccc4c(c3)Nc3nccnc3S4)CC2)C1 CHEMBL4167985 IC50 420.0 nM
O=C(O)C1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4162975 IC50 420.0 nM
CC(CCC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)C(=O)O CHEMBL4174342 IC50 420.0 nM
C/C(=C\CC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)C(=O)O CHEMBL4167939 IC50 420.0 nM
CC(C)(CCC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1)C(=O)O CHEMBL4175795 IC50 420.0 nM
O=C(O)c1ccc(C2CCN(Cc3ccc4c(c3)Nc3nccnc3S4)CC2)cc1 CHEMBL4171283 IC50 420.0 nM
O=C(O)c1ccc(CC2CCN(Cc3ccc4c(c3)Nc3nccnc3S4)CC2)cc1 CHEMBL4160680 IC50 420.0 nM
O=C(O)CC1CC2CCC(C1)N(Cc1ccc3c(c1)Nc1nccnc1S3)C2 CHEMBL4161090 IC50 420.0 nM
COc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL119532 IC50 430.0 nM
O=C(O)CCC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4166428 IC50 470.0 nM
CCCCCCCCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 CHEMBL119861 IC50 490.0 nM
O=C(O)CC1CCN(Cc2ccc3c(c2)Nc2nccnc2S3)CC1 CHEMBL4170903 IC50 530.0 nM
Cc1ccc(Sc2cncc3sc(CO)cc23)cc1 CHEMBL268530 IC50 540.0 nM
Cc1occc1Sc1cncc2sc(C(N)=O)cc12 CHEMBL267938 IC50 570.0 nM
CNC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCC(O)CO)cc3)cncc2s1 CHEMBL118358 IC50 580.0 nM
Cc1cc(Cl)ccc1Oc1cncc2sc(C(N)=O)cc12 CHEMBL115432 IC50 580.0 nM
CNC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCCN(CCO)CCO)cc3)cncc2s1 CHEMBL116958 IC50 600.0 nM
Cc1ccc(Sc2cncc3sc(C(=O)NCC(O)CO)cc23)cc1 CHEMBL428508 IC50 600.0 nM
CNC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCCc4c[nH]cn4)cc3)cncc2s1 CHEMBL119711 IC50 670.0 nM
CCOC(=O)c1cccc(Oc2cncc3sc(C(N)=O)cc23)c1 CHEMBL323832 IC50 680.0 nM
NC(=O)c1cc2c(Oc3ccc(C(O)CO)cc3)cncc2s1 CHEMBL115462 IC50 680.0 nM
NC(=O)c1cc2c(SCc3ccc(Cl)cc3)cncc2s1 CHEMBL269570 IC50 690.0 nM
O=C(/C=C/c1ccc(Sc2ccc(Cl)cc2Cl)c(Cl)c1)NCCCN1CCCC1=O CHEMBL316691 IC50 700.0 nM
CCC(F)(F)c1cc(N2CCC(S(C)(=O)=O)CC2)nc2sc(C(N)=O)c(N)c12 CHEMBL4522930 EC50 700.0 nM
CNC(=O)c1cc2c(Oc3ccc(C(=O)NCCN4CCOCC4)cc3)cncc2s1 CHEMBL119348 IC50 730.0 nM
NC(=O)c1cc2c(Oc3cccc(C(F)(F)F)c3)cncc2s1 CHEMBL115534 IC50 760.0 nM
NC(=O)c1cc2c(Oc3cccc(Cl)c3)cncc2s1 CHEMBL325893 IC50 770.0 nM
C=CCc1ccccc1Oc1cncc2sc(C(N)=O)cc12 CHEMBL325286 IC50 780.0 nM
NC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCC(O)CO)cc3)cncc2s1 CHEMBL421231 IC50 790.0 nM
NC(=O)c1cc2c(Oc3ccc(/C=C/C(=O)NCCN(CCO)CCO)cc3)cncc2s1 CHEMBL119522 IC50 820.0 nM
NC(=O)c1cc2c(Oc3ccc(C(=O)N4CCOCC4)cc3)cncc2s1 CHEMBL117367 IC50 830.0 nM
NC(=O)c1cc2c(SC3CCCCC3)cncc2s1 CHEMBL268099 IC50 840.0 nM