C[C@H](COc1cccc(-n2ccnc2C2CC2)c1)Oc1ccc(C#N)cc1F CHEMBL4443354 IC50 0.002 nM
COc1cc(C#N)ccc1O[C@@H](C)COc1cccc(-n2ccnc2C2CC2)c1 CHEMBL4558383 IC50 0.003 nM
COc1cc(C#N)ccc1O[C@@H](C)COc1cccc(-n2ccnc2C)c1 CHEMBL4583704 IC50 0.08 nM
N#Cc1ccc(OCCOc2cccc(-n3ccnc3C3CC3)c2)c(Cl)c1 CHEMBL4446351 IC50 0.1 nM
N#Cc1ccc(OCCOc2cccc(-n3ccnc3C3CC3)c2)cc1 CHEMBL4449942 IC50 0.16 nM
Cc1nccn1-c1cccc(OCCOc2ccc(C#N)cc2Cl)c1 CHEMBL4468997 IC50 0.2 nM
COc1cc(C#N)ccc1OCCOc1cccc(-n2ccnc2C)c1 CHEMBL4446048 IC50 0.2 nM
C[C@@H](COc1cccc(-c2ccnn2C)c1)Oc1ccc(C#N)cc1F CHEMBL4464629 IC50 0.7 nM
COc1cc(C#N)ccc1OCCOc1cccc(-c2ccnn2C)c1 CHEMBL4473893 IC50 0.9 nM
COc1cccc(NCCC2(c3ccccc3)CC(C)(C)OC(C)(C)C2)c1 CHEMBL1800705 IC50 1.0 nM
Cc1cc(C#N)ccc1O[C@@H](C)COc1cccc(-c2ccnn2C)c1 CHEMBL4445788 IC50 1.6 nM
CC1(C)CC(CCNc2cccc(Cl)c2)(c2cccs2)CCO1 CHEMBL1800516 IC50 3.8 nM
COc1cccc(NCCC2(c3cccc(F)c3)CCOC(C)(C)C2)c1 CHEMBL1800513 IC50 8.0 nM
COc1cccc(NCC[C@@]2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800715 IC50 10.0 nM
COc1cccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800426 IC50 15.0 nM
CC1(C)CC(CCNc2ccccc2)(c2ccccc2)CC(C)(C)O1 CHEMBL1800522 IC50 15.0 nM
COc1cccc(NCCC2(c3cccs3)CCOC(C)(C)C2)c1 CHEMBL1800514 IC50 19.0 nM
CC1(C)CC(CCNc2cccc(Cl)c2)(c2ccccc2)CCO1 CHEMBL1800485 IC50 25.0 nM
CC1(C)CC(CCNc2ccc(F)c(Cl)c2)(c2ccccc2)CCO1 CHEMBL1800498 IC50 25.0 nM
CC1(C)CC(CCNc2cccc([N+](=O)[O-])c2)(c2ccccc2)CCO1 CHEMBL1800501 IC50 26.0 nM
Cc1cccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800417 IC50 31.0 nM
Cc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1 CHEMBL1800418 IC50 31.0 nM
COc1c(F)cc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1F CHEMBL1800496 IC50 31.0 nM
CC1(C)CC(CCNc2cc(Cl)ccc2F)(c2ccccc2)CCO1 CHEMBL1800499 IC50 32.0 nM
CCc1cccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800421 IC50 40.0 nM
Cc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1Cl CHEMBL1800490 IC50 49.0 nM
CC1(C)CC(CCNc2cccc(F)c2)(c2ccccc2)CCO1 CHEMBL1800492 IC50 52.0 nM
Cc1cc(C)cc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800420 IC50 54.0 nM
CC1(C)CC(CCNc2cccc(C#N)c2)(c2ccccc2)CCO1 CHEMBL1800483 IC50 66.0 nM
Cc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1C CHEMBL1800419 IC50 69.0 nM
COc1cc(NCCC2(c3ccccc3)CCOC(C)(C)C2)ccc1C CHEMBL1800477 IC50 90.0 nM
CC1(C)CC(CCNc2cccc(OC(F)(F)F)c2)(c2ccccc2)CCO1 CHEMBL1800479 IC50 90.0 nM
COc1cccc(NCCC2(c3ccc(F)cc3)CCOC(C)(C)C2)c1 CHEMBL1800512 IC50 100.0 nM
CC1(C)CC(CCN(Cc2ccccc2)C(=O)c2ccco2)(c2ccccc2)CCO1 CHEMBL1484316 IC50 120.0 nM
CC1(C)CC(CCNc2ccc(C#N)cc2)(c2ccccc2)CCO1 CHEMBL1800484 IC50 123.0 nM
CN(C)c1cccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800481 IC50 131.0 nM
CC(C)c1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1 CHEMBL1800423 IC50 132.0 nM
COc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1F CHEMBL1800495 IC50 160.0 nM
CC(C)c1cccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800422 IC50 167.0 nM
CC1(C)CC(CCNc2ccc(F)cc2)(c2ccccc2)CCO1 CHEMBL1800493 IC50 168.0 nM
CC1(C)CC(CCNc2cc(Cl)cc(Cl)c2)(c2ccccc2)CCO1 CHEMBL1800487 IC50 170.0 nM
CC1(C)CC(CCNc2ccc(Cl)c(Cl)c2)(c2ccccc2)CCO1 CHEMBL1800488 IC50 181.0 nM
CC1(C)CC(CCNc2ccc(OC(F)(F)F)cc2)(c2ccccc2)CCO1 CHEMBL1800480 IC50 184.0 nM
COc1cccc(NCCC2(c3cccc(Cl)c3)CCOC(C)(C)C2)c1 CHEMBL1800511 IC50 190.0 nM
COc1cccc(NCC[C@]2(c3ccccc3)CCOC(C)(C)C2)c1 CHEMBL1800714 IC50 230.0 nM
COc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1 CHEMBL1800476 IC50 270.0 nM
CC1(C)CC(CCNc2ccccc2)(c2cccs2)CCO1 CHEMBL1800515 IC50 270.0 nM
Cc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)c(F)c1 CHEMBL1800494 IC50 300.0 nM
Cc1cc(NCCC2(c3ccccc3)CCOC(C)(C)C2)ccc1Cl CHEMBL1800489 IC50 308.0 nM
CC1(C)CC(CCN(CC(=O)c2ccco2)c2ccccc2)(c2ccccc2)CCO1 CHEMBL1800360 IC50 310.0 nM
CC1(C)CC(CCNc2ccc(Cl)cc2)(c2ccccc2)CCO1 CHEMBL1800486 IC50 360.0 nM
CC1(C)CC(CCNc2cccc(C(F)(F)F)c2)(c2ccccc2)CCO1 CHEMBL1800500 IC50 380.0 nM
COC(=O)CCSC/C=C(\C)CCn1cc(CCc2ccc(-c3ccccc3)cc2)nn1 CHEMBL2035530 IC50 400.0 nM
COc1cccc(NCCC2(c3ccccc3)CC(C)(C)SC(C)(C)C2)c1 CHEMBL1800708 IC50 420.0 nM
Cc1ccc(NCCC2(c3ccccc3)CCOCC2)cc1Cl CHEMBL1800521 IC50 460.0 nM
CC1(C)CC(CCNc2ccc(Cl)c(F)c2)(c2ccccc2)CCO1 CHEMBL1800497 IC50 470.0 nM
CCCCCCCCn1cc(CN2CCCC2)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258894 IC50 500.0 nM
CSCC[C@@H](NC(=O)c1ccc(CNCc2c[nH]cn2)cc1-c1ccccc1C)C(=O)OCc1ccccc1 CHEMBL1800361 IC50 500.0 nM
CC1(C)CC(CCNc2ccccc2F)(c2ccccc2)CCO1 CHEMBL1800491 IC50 550.0 nM
CC1(C)CC(CCNc2cccc(C(C)(C)C)c2)(c2ccccc2)CCO1 CHEMBL1800424 IC50 556.0 nM
CCCCCCCCn1cc(CN(CC)CC)c2cc(-c3ccccc3C)ccc21 CHEMBL1257624 IC50 600.0 nM
CCCCCCCCn1cc(CN(CC)CC)c2cc(-c3ccc(C)cc3)ccc21 CHEMBL1257625 IC50 600.0 nM
COc1cccc(NCCC2(c3ccc(Cl)cc3)CCOC(C)(C)C2)c1 CHEMBL1800510 IC50 630.0 nM
COc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1OC CHEMBL1800478 IC50 652.0 nM
CC1(C)CC(CCNc2ccc([N+](=O)[O-])cc2)(c2ccccc2)CCO1 CHEMBL1800502 IC50 682.0 nM
CCCCCCCCn1cc(CN)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258547 IC50 700.0 nM
CCCCCCCCn1cc(CN(CC)CC)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258659 IC50 700.0 nM
CCCCCCCCn1cc(CN2CCCCC2)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258895 IC50 700.0 nM
CC1(C)CC(CCNc2ccc(C(C)(C)C)cc2)(c2ccccc2)CCO1 CHEMBL1800425 IC50 760.0 nM
COc1cccc(NCCC2(c3ccccc3)CCOCC2)c1 CHEMBL1800518 IC50 777.0 nM
CCCCCCCCn1cc(CN(CCC)CCC)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258775 IC50 800.0 nM
CCCCCCCCn1cc(CC(=O)N(CC)CC)c2cc(-c3cccc(OC)c3)ccc21 CHEMBL1258097 IC50 800.0 nM
CCCCCCCCn1cc(CN(CC)CC)c2cc(-c3cnc(N)nc3)ccc21 CHEMBL2376504 IC50 860.0 nM
CC(C)=CCC/C(C)=C/CC/C(C)=C/CSCCO CHEMBL3219960 IC50 860.0 nM
CCCCCCCCn1cc(CN(C)C(C)C)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258776 IC50 900.0 nM
CCCCCCCCn1cc(CN2CCN(C)CC2)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1257159 IC50 900.0 nM
CCCCCCCCn1cc(CN(CC)CC)c2cc(-c3ccncc3F)ccc21 CHEMBL2376433 IC50 960.0 nM
CCCCCCCCn1cc(CC(N)=O)c2cc(-c3ccccc3C)ccc21 CHEMBL1257623 IC50 1000.0 nM
CCCCCCCCn1cc(CC(N)=O)c2cc(-c3ccc(C)cc3)ccc21 CHEMBL392347 IC50 1000.0 nM
CC(C)=CCC/C(C)=C/Cn1cc(CC(N)=O)c2cc(-c3cccc(C)c3)ccc21 CHEMBL1258096 IC50 1000.0 nM
CCCCCCCCn1cc(CC(=O)N(CC)CC)c2cc(-c3cccc(OCC)c3)ccc21 CHEMBL1258098 IC50 1000.0 nM
CC1(C)CC(CCNc2ccccc2)(c2ccccc2)CCO1 CHEMBL1800415 IC50 1000.0 nM