O=C1c2cc([N+](=O)[O-])ccc2-n2c1nc1ccccc1c2=O CHEMBL432537 IC50 0.018 nM
O=C(Nc1ccc(C2(C(=O)Nc3ccc(Cl)nc3)CCC2)cc1)c1cccc(Cl)c1 CHEMBL4633874 fIC50 0.04 nM
O=C(Nc1ccc(C2(C(=O)Nc3ccc(F)cc3)CCC2)cc1)c1cccc(Cl)c1 CHEMBL4638223 fIC50 0.05 nM
Cc1cc(C2CC2)ncc1-c1ccc(C2(C(=O)Nc3ccc(F)cc3)COC2)cc1 CHEMBL5207194 IC50 0.08 nM
O=C(Nc1ccc(C2(C(=O)Nc3ccc(F)cc3)COC2)cc1)c1cccc(Cl)c1 CHEMBL4645108 fIC50 0.09 nM
O=C(Nc1ccc(F)cc1)C1(C2CCC3C(CCCN3c3ccnc(C(F)(F)F)n3)C2)CCC1 CHEMBL4863767 IC50 0.1 nM
CC(C)(O)c1cc(C(F)(F)F)ncc1-c1ccc(C2(C(=O)Nc3ccc(F)cc3)COC2)cc1 CHEMBL5192384 Ki 0.11 nM
O=C1CC(c2c[nH]c3ccc(F)cc23)C(=O)N1 CHEMBL4086143 IC50 0.12 nM
C[C@@H](C(=O)Nc1ccc(F)cc1)C1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1 CHEMBL4855797 IC50 0.13 nM
O=C(Nc1ccc(F)cc1)C1(c2ccc(-c3cnc(C(F)(F)F)cc3CO)cc2)COC1 CHEMBL5192977 Ki 0.15 nM
Cc1nccc(N2CCCC3CC(C4(C(=O)Nc5ccc(F)cc5)CCC4)CCC32)n1 CHEMBL4848630 IC50 0.29 nM
O=C(Nc1ccc(C2(C(=O)Nc3ccc(F)cc3)CCC2)cn1)c1cccc(Cl)c1 CHEMBL4635112 fIC50 0.3 nM
O=C(Nc1ccc(Cl)cc1)C1(c2ccc3c(n2)CCN3c2ccccn2)CCC1 CHEMBL4848098 IC50 0.34 nM
O=C(OC1CC1)N1CCc2cc(C3(C(=O)Nc4ccc(F)cc4)CCC3)ccc21 CHEMBL4872023 IC50 0.45 nM
Cc1cc(NC(=O)Nc2cc([C@H]3C[C@H]3C(=O)O)ccc2N(CC(C)C)C2CCCCC2)on1 CHEMBL3745883 IC50 0.5 nM
C[C@@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4161733 IC50 0.5 nM
C[C@@H](C(=O)Nc1ccc(Cl)cc1)C1CCC(c2ccnc3ccc(F)cc23)CC1 CHEMBL4297598 IC50 0.5 nM
Fc1cc2ncn([C@H]3C[C@@H]4[C@@H](CNC(c5ccc(Cl)cc5)C(F)(F)F)[C@@H]4C3)c2cc1F CHEMBL4873747 IC50 0.52 nM
Cc1cccc(N2CCN(C(=O)Cn3nc(C(=O)N4CC[C@@H](O)[C@H](F)C4)c4c3C[C@H]3C[C@@H]43)CC2)c1C CHEMBL4879235 IC50 0.59 nM
CC(=O)NC1CCN(C(=O)c2nn(CC(=O)N3CCN(c4cccc(C)c4Cl)CC3)c3c2C2CCCCC2C3)CC1 CHEMBL4861457 IC50 0.59 nM
O=C(Nc1ccc(C2(C(=O)Nc3ccc(F)cc3)COC2)nc1)c1cccc(Cl)c1 CHEMBL4632601 fIC50 0.6 nM
C[C@H](C(=O)Nc1ccc(Cl)cc1)C12CC(NC(=O)c3cccc(Cl)c3)(C1)C2 CHEMBL4642946 IC50 0.6 nM
CC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](c3ccnc4ccc(F)cc34)C[C@@H]21 CHEMBL4856710 IC50 0.6 nM
O=C(NC1(c2ccc3c(n2)CCN3C(=O)OC2CC2)CCC1)c1ccc(Cl)cc1 CHEMBL4869600 IC50 0.63 nM
Cc1c(F)ccc(N2CCN(C(=O)Cn3nc(C(=O)N4CCC(O)C(CO)C4)c4c3C[C@H]3C[C@@H]43)C3(CC3)C2)c1C CHEMBL4867998 IC50 0.64 nM
CC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4858888 IC50 0.69 nM
O=C(OC1CC1)N1CCCc2nc(C3(c4nc5ccc(Cl)cc5[nH]4)CCC3)ccc21 CHEMBL4862659 IC50 0.6928 nM
CC(C(=O)Nc1ccc(Cl)cc1)N1CCC2C(CCCN2C(=O)OC2CC2)C1 CHEMBL4848366 IC50 0.73 nM
C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2c(n1)CCCN2C(=O)c1cccc(Cl)c1 CHEMBL4744727 fIC50 0.75 nM
C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2c(n1)CCCN2C(=O)OC1CCC1 CHEMBL4764710 IC50 0.8 nM
Cc1nccc(N2C[C@@H]3C[C@@H]3c3nc(C4(NC(=O)c5ccc(F)cc5)CC4)ccc32)n1 CHEMBL4870929 fIC50 0.8 nM
O=C(Nc1ccc(F)cc1)C1(c2ccc(-c3cnc(C(F)(F)F)cc3CO)cc2)CC(F)(F)C1 CHEMBL5173861 IC50 0.8 nM
O=C(c1cccc(Cl)c1)N1CCc2nc(C3(C(=O)Nc4ccc(F)cc4)CCC3)ccc21 CHEMBL4855740 IC50 0.84 nM
O=C(C1CC1)N1CCCC2CC(C3(C(=O)Nc4ccc(F)cc4)CCC3)CCC21 CHEMBL4858599 IC50 0.86 nM
CCC(c1nc2cc(Cl)ccc2[nH]1)[C@H]1[C@@H]2C[C@@H](c3ccnc4ccc(F)cc34)C[C@@H]21 CHEMBL4849690 IC50 0.92 nM
O=C(c1ccccc1Cl)N1CCCc2nc(C3(c4nc5ncc(C(F)(F)F)cc5[nH]4)CCC3)ccc21 CHEMBL4848644 IC50 0.9583 nM
O=C(c1cccc(Cl)c1)N1CCCC2CC(C3(C(=O)Nc4ccc(F)cc4)CCC3)CCC21 CHEMBL4849622 IC50 0.98 nM
C[C@@H](c1ccc2c(n1)CCCN2C(=O)OC1CC1)c1nc2ccc(Cl)cc2[nH]1 CHEMBL4865877 IC50 0.9819 nM
O=C1c2nnn(Cc3ccccc3)c2C(=O)c2nnn(Cc3ccccc3)c21 CHEMBL4746602 IC50 1.0 nM
Cc1nccc(N2CCCc3nc([C@]4(NC(=O)c5ccc(F)cc5)C[C@@H]4C)ccc32)n1 CHEMBL4862297 fIC50 1.0 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@@H]1[C@@H]2C[C@H](Oc3ccnc4ccc(F)cc34)C[C@@H]21 CHEMBL4875089 IC50 1.0 nM
CC(c1ccc2c(n1)CCCN2C(=O)OC1CC1)c1nc2ccc(Cl)cc2[nH]1 CHEMBL4852107 IC50 1.147 nM
O=C(NC1(c2ccc3c(n2)CCCN3c2ccnc(C(F)(F)F)n2)CC1)c1ccc(F)cc1 CHEMBL4847724 IC50 1.2 nM
Cc1nccc(N2CCCc3nc(C4(NC(=O)c5ccc(F)cc5)CC4)ccc32)n1 CHEMBL4859249 IC50 1.2 nM
O=C(Nc1ccc(F)cc1)C1(c2ccc(-c3cnc(C(F)(F)F)cc3CO)cc2)CCC1 CHEMBL5193283 IC50 1.2 nM
O=C(OC1CC1)N1CCCc2nc(C3(c4nc5ncc(C(F)(F)F)cc5[nH]4)CCC3)ccc21 CHEMBL4853215 IC50 1.349 nM
O=C(OC1CC1)N1CCCc2nc(C3(c4nc5ncc(Cl)cc5[nH]4)CCC3)ccc21 CHEMBL4850401 IC50 1.375 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@@H]1[C@@H]2C[C@H](Oc3ccnc4cc(F)ccc34)C[C@@H]21 CHEMBL4868112 IC50 1.4 nM
Cc1ccc(NC(=O)Nc2cc(-c3ccccc3-c3nc(=O)[nH]o3)cc3c2OCCCC3c2ccccc2)cc1 CHEMBL5273615 IC50 1.5 nM
Nc1nonc1/C(=N/O)N1Cc2ccccc2C1 CHEMBL4797341 IC50 1.57 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)c1ccc2c(n1)CCCN2C(=O)c1cccc(Cl)c1 CHEMBL4755227 IC50 1.6 nM
O=C(Nc1ccc(Cl)cc1)C1(c2ccc3c(c2)CCN3c2ccccn2)CCC1 CHEMBL4875994 IC50 1.6 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@@H]1[C@@H]2C[C@@H](Oc3ccnc4ccccc34)C[C@@H]21 CHEMBL4872522 IC50 1.6 nM
C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2c(n1)CCCN2c1ccncn1 CHEMBL4779920 IC50 1.7 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4861332 IC50 1.7 nM
CS(=O)(=NC#N)NCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL4167184 IC50 1.8 nM
C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2c(n1)CCCN2c1ccnc(C(F)(F)F)n1 CHEMBL4783395 IC50 1.8 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(NC(=O)c3ccc(F)c(F)c3)(C1)C2 CHEMBL4644751 IC50 1.9 nM
C[C@@H](NC(=O)c1ccc(-c2ccccc2)cc1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4743409 IC50 2.0 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4786690 IC50 2.0 nM
CCC(c1nc2ncc(Cl)cc2[nH]1)[C@H]1CC[C@@H](c2ccnc3ccc(C(F)(F)F)cc32)CC1 CHEMBL4756822 IC50 2.0 nM
CCC(c1nc2ncc(Cl)cc2[nH]1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4750659 IC50 2.0 nM
CCC(c1nc2ccc(Cl)cc2[nH]1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4750211 IC50 2.0 nM
O=C(CN1CCC2C(CCCN2C(=O)c2cccc(Cl)c2)C1)Nc1ccc(F)cc1 CHEMBL4852537 IC50 2.0 nM
O=C(OC1CC1)N1CCc2nc(C3(C(=O)Nc4ccc(Cl)cc4)CCC3)ccc21 CHEMBL4865753 IC50 2.0 nM
CC[C@@H](NC(=O)c1ccc(OC)nc1)[C@H]1CC[C@@H](c2ccnc(OC)c2C(F)F)CC1 CHEMBL4848094 IC50 2.0 nM
COC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc(OC)c2C(F)F)CC1 CHEMBL4851220 IC50 2.0 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc(OC)c2C(F)F)CC1 CHEMBL4845988 IC50 2.0 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc(OC)c2C)CC1 CHEMBL4868709 IC50 2.0 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(NC(=O)c3ccc(F)c(Cl)c3)(C1)C2 CHEMBL4648765 IC50 2.1 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(NC(=O)c3cc(F)cc(Cl)c3)(C1)C2 CHEMBL4647172 IC50 2.1 nM
OCCOCc1cn(CCNc2nonc2/C(=N/O)Nc2ccc(F)c(Br)c2)nn1 CHEMBL5091825 IC50 2.16 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4ccc(F)cc43)C[C@@H]21 CHEMBL4859064 IC50 2.2 nM
Cc1cc(C(F)(F)F)ncc1-c1ccc(C2(C(=O)Nc3ccc(F)cc3)COC2)cc1 CHEMBL5180607 IC50 2.2 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cn[nH]c13)c1cc(CC)ccc1O2 CHEMBL4517539 IC50 2.5 nM
C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2c(n1)CCCN2C(=O)OC1CC1 CHEMBL4749009 IC50 2.6 nM
CC(C)CN(c1ccc(-c2c(C(=O)O)ccc3ccccc23)cc1NC(=O)Nc1ccc(Br)cc1F)C1CCCCC1 CHEMBL4782139 IC50 2.6 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)ccc43)C[C@@H]21 CHEMBL4866113 IC50 2.6 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4ccc(F)cc43)C[C@@H]21 CHEMBL4866976 IC50 2.6 nM
COP(C)(=O)NCCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL4791168 IC50 2.6 nM
O=C(OC1CC1)N1CCc2nc(C3(C(=O)Nc4ccc(F)cc4)CCC3)ccc21 CHEMBL4864878 IC50 2.7 nM
NS(=O)(=O)NCCSc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL4452336 IC50 2.8 nM
COC(=O)N1c2ccc(C3(NC(=O)c4ccc(F)cc4)CC3)cc2[C@H]2CC[C@H]21 CHEMBL4849318 IC50 2.8 nM
Cc1nccc(N2CCCC3CN(C(C)C(=O)Nc4ccc(Cl)cc4)CCC32)n1 CHEMBL4853448 IC50 2.9 nM
Cc1nccc(N2c3ccc(C4(NC(=O)c5ccc(F)cc5)CC4)cc3[C@H]3C[C@H]32)n1 CHEMBL4847481 IC50 2.9 nM
CCCC(CCC)Oc1c(Br)cc(-c2ccccc2-c2nnn[nH]2)cc1NC(=O)Nc1ccccc1F CHEMBL3746645 IC50 3.0 nM
CC(C)CN(CC(C)C)c1ccc(C(CC(=O)O)C(F)(F)F)cc1NC(=O)Nc1ccc(F)cc1F CHEMBL3746887 IC50 3.0 nM
NS(=O)(=O)NC1(CCNc2nonc2/C(=N/O)Nc2ccc(F)c(Br)c2)CC1 CHEMBL4166767 IC50 3.0 nM
CCCNC(=O)C1(c2ccc(NC(=O)c3ccc(F)c(C)c3)cc2)CCC1 CHEMBL4637907 fIC50 3.0 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)c1ccc2c(c1)OCCN2C(=O)c1cccc(Cl)c1 CHEMBL4744926 IC50 3.0 nM
CCOC(=O)N1CCCc2nc([C@@H](C)NC(=O)c3ccc(F)cc3)ccc21 CHEMBL4788473 IC50 3.0 nM
C[C@@H](c1nc2ccc(Cl)cc2[nH]1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4755937 IC50 3.0 nM
COCC(Nc1nnc(-c2ccc(OC)cc2)o1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4796040 IC50 3.0 nM
CCC(Nc1nnc(-c2ccc(OC)cc2)o1)[C@H]1CC[C@@H](c2ccnc3c(F)cc(F)cc32)CC1 CHEMBL4746203 IC50 3.0 nM
CCC(Nc1nnc(-c2ccc(OC)cc2)o1)[C@H]1CC[C@@H](c2ccnc3ccc(C(F)(F)F)cc32)CC1 CHEMBL4763467 IC50 3.0 nM
C[C@@H](c1nc2cc(F)ccc2[nH]1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4780978 IC50 3.0 nM
COc1ccc(-c2nnc(N[C@H](C)[C@H]3CC[C@@H](c4ccnc5ccc(F)cc54)CC3)o2)cc1 CHEMBL4750132 IC50 3.0 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc(OC)c2F)CC1 CHEMBL4860353 IC50 3.0 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(NC(=O)c3cccc(Cl)c3)(C1)C2 CHEMBL4632992 IC50 3.1 nM
O=C(Nc1ccc(F)cc1)C1(c2ccc3c(c2)CCN3c2ccccn2)CCC1 CHEMBL4877196 IC50 3.1 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(Nc3ncnc4ccc(F)cc34)(C1)C2 CHEMBL4647108 IC50 3.2 nM
Cc1oc(C)c(-c2ccc(N(CC(C)C)C3CCCCC3)c(NC(=O)Nc3ccccc3F)c2)c1C(=O)O CHEMBL4535597 IC50 3.3 nM
CCN(C(=O)N1CCc2cc(C3(C(=O)Nc4ccc(Cl)cc4)CCC3)ccc21)C(C)C CHEMBL4873156 IC50 3.3 nM
NS(=O)(=O)NCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL3545369 IC50 3.4 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4ccc(Cl)cc43)C[C@@H]21 CHEMBL4863359 IC50 3.4 nM
C=CC1(C=C)Oc2c(NC(=O)Nc3ccc(C)cc3)cc(-c3ccccc3-c3nn[nH]n3)cc2[C@@H]1c1ccccc1 CHEMBL5279540 IC50 3.4 nM
CC1=C(CC(=O)c2sccc2Br)C(=O)c2ccccc2C1=O CHEMBL5220107 IC50 3.42 nM
CC(C(=O)Nc1ccc(Cl)cc1)N1CCC2C(CCCN2c2ccnc(C(F)(F)F)n2)C1 CHEMBL4847151 IC50 3.6 nM
Cc1nccc(N2CCCc3nc([C@@H](C)NC(=O)c4ccc(F)cc4)ccc32)n1 CHEMBL4779248 IC50 3.6 nM
O=C(N[C@H](C1CC1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21)c1ccc(Cl)cc1 CHEMBL4846356 IC50 3.6 nM
Cc1ccc(NC(=O)Nc2cc(-c3ccccc3-c3nn[nH]n3)cc3c2OCCCC3c2ccccc2)cc1 CHEMBL5267407 IC50 3.6 nM
Cc1nccc(N2c3ccc(C4(NC(=O)c5ccc(F)cc5)CC4)cc3[C@H]3CC[C@H]32)n1 CHEMBL4863701 IC50 3.8 nM
C[C@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@]2(CC1)COc1cc(C(F)(F)F)ccc12 CHEMBL4763375 IC50 3.9 nM
C[C@@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4861395 IC50 3.9 nM
CC[C@@H](NC(=O)c1ccc(Cl)c(F)c1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4869547 IC50 3.9 nM
Cc1ccc(NC(=O)Nc2cc(-c3ccccc3-c3nnn[nH]3)ccc2N(CC(C)C)CC(C)C)cc1 CHEMBL4207581 IC50 4.0 nM
Cc1nsc(Nc2cc(-c3c(C)oc(C)c3C(=O)O)ccc2N(CC(C)C)C2CCCCC2)n1 CHEMBL4562263 IC50 4.0 nM
C[C@@H](c1nc2ncc(Cl)cc2[nH]1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4779097 IC50 4.0 nM
Cc1nccc([C@H]2CC[C@@H]([C@@H](C)NC(=O)c3ccc(Cl)cc3)CC2)c1C CHEMBL4877466 IC50 4.0 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4ccc(F)c(F)c43)C[C@@H]21 CHEMBL4856417 IC50 4.0 nM
Cn1cc(-c2ccc(NC(=O)N3CCC(C(=O)/C(=N/O)Nc4ccc(F)c(Br)c4)CC3)cc2)cn1 CHEMBL4747226 IC50 4.0 nM
O=C(NC1(c2ccc3c(n2)CCN3C(=O)OC2CC2)CC1)c1ccc(Cl)cc1 CHEMBL4847565 IC50 4.1 nM
Cc1ccc(NC(=O)Nc2cc(-c3c(C)oc(C)c3C(=O)O)ccc2N(CC(C)C)C2CCCCC2)cc1 CHEMBL4591635 IC50 4.2 nM
Cc1ccc(NC(=O)Nc2cc([C@H]3C[C@H]3C(=O)O)ccc2N(CC(C)C)CC(C)C)cc1 CHEMBL4777480 IC50 4.2 nM
O=C(NC[C@H]1[C@H]2C[C@@H](Oc3ccnc4ccc(F)cc34)C[C@@H]12)c1ccc(Cl)cc1 CHEMBL4873928 IC50 4.2 nM
COC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cn[nH]c13)c1cc(Br)ccc1O2 CHEMBL4533779 IC50 4.3 nM
O=C(Nc1ccc(Cl)cc1)C(CC1CC1)N1CCC2(CC1)COc1cc(C(F)(F)F)ccc12 CHEMBL4745769 IC50 4.4 nM
CC[C@@H](NC(=O)c1ccc(C#N)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4853672 IC50 4.4 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3c1NC(=O)CO3)c1cc(Br)ccc1O2 CHEMBL4443475 IC50 4.5 nM
Cc1csc(Nc2cc(-c3c(C)oc(C)c3C(=O)O)ccc2N(CC(C)C)C2CCCCC2)n1 CHEMBL4555117 IC50 4.6 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4858219 IC50 4.6 nM
CC(C)OC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cn[nH]c13)c1cc(Br)ccc1O2 CHEMBL4520765 IC50 4.8 nM
Cc1ccc(CC(=O)Nc2cc(-c3ccccc3-c3nnn[nH]3)ccc2N2CC3CC2CN3Cc2ccccc2)cc1 CHEMBL3747340 IC50 5.0 nM
Cc1ccc(CC(=O)Nc2cc(-c3ccccc3-c3nnn[nH]3)ccc2N(CC(C)C)CC(C)C)cc1 CHEMBL4218193 IC50 5.0 nM
O=C(Nc1ccc(Cl)cc1F)C(=O)N1CCC=C(c2ccnc3ccc(F)cc23)CC1 CHEMBL4749799 IC50 5.0 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)c1ccc2c(c1)CCCN2C(=O)c1cccc(Cl)c1 CHEMBL4799004 IC50 5.0 nM
O=C1c2cc(F)ccc2C(=O)c2c1nnn2-c1ccc(F)c(Cl)c1 CHEMBL4787695 IC50 5.0 nM
Cc1nccc(N2c3ccc(C4(NC(=O)c5ccc(F)cc5)CC4)cc3[C@@H]3CC[C@@H]32)n1 CHEMBL4862039 IC50 5.0 nM
Cc1c(F)nccc1[C@H]1CC[C@@H]([C@@H](C)NC(=O)c2ccc(Cl)cc2)CC1 CHEMBL4859400 IC50 5.0 nM
Cc1nnc(Nc2cc(-c3c(C)oc(C)c3C(=O)O)ccc2N(CC(C)C)C2CCCCC2)s1 CHEMBL4593106 IC50 5.1 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(NC(=O)c3cccc(Cl)c3F)(C1)C2 CHEMBL4643223 IC50 5.1 nM
C[C@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@@]2(CC1)COc1cc(C(F)(F)F)ccc12 CHEMBL4741630 IC50 5.1 nM
O=C(NC12CC(C3(C(=O)Nc4ccc(F)cc4)CCC3)(C1)C2)c1cccc(Cl)c1 CHEMBL4643811 IC50 5.2 nM
C[C@H](C(=O)Nc1ccc(Cl)nc1)C12CC(NC(=O)c3cccc(Cl)c3)(C1)C2 CHEMBL4638557 IC50 5.2 nM
Cc1nccc(N2CCc3cc(C4(C(=O)Nc5ccc(F)cc5)CCC4)ccc32)n1 CHEMBL4851625 IC50 5.2 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cccc(F)c43)C[C@@H]21 CHEMBL4866916 IC50 5.2 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4849414 IC50 5.3 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cn[nH]c13)c1cc(Br)ccc1O2 CHEMBL4550298 IC50 5.4 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(Nc3ncnc4ccccc34)(C1)C2 CHEMBL4641517 IC50 5.4 nM
C[C@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@]2(CC1)COc1nc(C(F)(F)F)ccc12 CHEMBL4745907 IC50 5.4 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cc[nH]c13)c1cc(Br)ccc1O2 CHEMBL4457477 IC50 5.6 nM
COC(=O)N1c2ccc(C3(NC(=O)c4ccc(F)cc4)CC3)cc2[C@@H]2CC[C@@H]21 CHEMBL4863227 IC50 5.6 nM
Cc1oc(C)c(-c2ccc(N(CC(C)C)C3CCCCC3)c(NC(=O)Nc3ccc(F)cc3)c2)c1C(=O)O CHEMBL4548296 IC50 5.7 nM
O[C@H](C[C@H]1c2c(F)cccc2-c2cncn21)[C@H]1CC[C@H](O)CC1 CHEMBL3989951 Ki 5.8 nM
CC(C)CN(CC(C)C)c1ccc([C@H](C)CC(=O)O)cc1NCNc1nc(C(F)(F)F)ns1 CHEMBL4789762 IC50 5.9 nM
C=C[C@@H]1Oc2c(NC(=O)Nc3ccc(C)cc3)cc(-c3ccccc3-c3nn[nH]n3)cc2[C@@H]1c1ccccc1 CHEMBL5269992 IC50 5.9 nM
Nc1nonc1/C(=N/O)N[C@H]1Cc2ccc(F)cc21 CHEMBL4475809 IC50 6.0 nM
CCC(Nc1nnc(-c2ccc(OC)cc2)o1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4752094 IC50 6.0 nM
O=C(Nc1ccc(Cl)cc1)C(=O)N1CC[C@H](c2ccnc3ccc(F)cc23)[C@@H](O)C1 CHEMBL4753967 IC50 6.1 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@@H]1[C@@H]2C[C@@H](Oc3ccnc4ccc(F)cc34)C[C@@H]21 CHEMBL4846874 IC50 6.1 nM
C[C@H](C(=O)Nc1ccc(F)cc1)C12CC(NC(=O)OC3CCCC3)(C1)C2 CHEMBL4639353 IC50 6.2 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](NC(=O)c3cncc(F)c3)C[C@@H]21 CHEMBL4854742 IC50 6.2 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)cc(F)c43)C[C@@H]21 CHEMBL4852566 IC50 6.2 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4ccccc43)C[C@@H]21 CHEMBL4878766 IC50 6.3 nM
CCOc1cc(CNC(=O)c2ncoc2-c2ccc(OC)cc2)cc(OCC)c1OCC CHEMBL5094068 IC50 6.3 nM
O=C(Nc1ccc(F)cc1)C1(c2ccc(-c3ccc(C4CC4)nc3)cc2)COC1 CHEMBL5192057 IC50 6.3 nM
Cc1ccc(NC(=O)Nc2cc(-c3ccccc3-c3nn[nH]n3)cc3c2OC(C)(C)[C@H]3c2ccccc2)cc1 CHEMBL5287356 IC50 6.3 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cn[nH]c13)c1nc(OC)ccc1O2 CHEMBL4459934 IC50 6.4 nM
N#CCC(=O)NCCSc1nonc1/C(=N/O)Nc1ccc(F)c(C(F)F)c1 CHEMBL4538516 IC50 6.5 nM
Cc1oc(C)c(-c2ccc(N(CC(C)C)CC(C)C)c(NC(=O)Nc3ccc(F)cc3F)c2)c1C(=O)O CHEMBL4537680 IC50 6.6 nM
C[C@@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@@]2(CC1)COc1cc(C(F)(F)F)ccc12 CHEMBL4758026 IC50 6.6 nM
COCCOC(=O)N1CCc2nc(C3(NC(=O)c4ccc(Cl)cc4)CCC3)ccc21 CHEMBL4869709 IC50 6.9 nM
CC(NC(=O)c1ccc(C#N)cc1)[C@H]1[C@@H]2C[C@@H](Oc3ncnc4cc(F)ccc34)C[C@@H]21 CHEMBL4853036 IC50 6.9 nM
NS(=O)(=O)NCCNC1=NON/C1=C(/NO)Nc1ccc(F)c(Br)c1 CHEMBL4242226 IC50 7.0 nM
OC(CC1c2ccccc2-c2cncn21)C1CCCCC1 CHEMBL3629569 Ki 7.0 nM
CC[C@H](C(=O)Nc1ccc(Cl)cn1)[C@H]1CC[C@]2(CC1)COc1cc(C(F)(F)F)ccc12 CHEMBL4761104 IC50 7.0 nM
O=C(Nc1ccc(Cl)cc1F)C(=O)N1CCC(c2ccnc3ccc(F)cc23)CC1 CHEMBL4740188 IC50 7.0 nM
COc1ccc(C(=O)N[C@H](C)[C@H]2CC[C@@H](c3ccnc4ccc(F)cc43)CC2)cc1N1CCOCC1 CHEMBL4747228 IC50 7.0 nM
C[C@@H](NC(=O)c1cccc(Cl)c1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4757725 IC50 7.0 nM
C[C@@H](CNc1ccc(Cl)cc1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4794508 IC50 7.0 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)c1ccc2c(c1)C(F)(F)CCN2C(=O)c1cccc(Cl)c1 CHEMBL4780616 IC50 7.0 nM
CCC(c1nc2ccc(Cl)cc2[nH]1)[C@H]1CC[C@H](Oc2ccnc3ccccc23)CC1 CHEMBL4743245 IC50 7.0 nM
C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2c(c1)CCN2C(=O)C1CCOCC1 CHEMBL4778760 IC50 7.0 nM
Cc1cnccc1[C@H]1CC[C@@H]([C@@H](C)NC(=O)c2ccc(Cl)cc2)CC1 CHEMBL4861763 IC50 7.0 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4c(F)cccc43)C[C@@H]21 CHEMBL4873803 IC50 7.0 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4c(F)cc(F)cc43)C[C@@H]21 CHEMBL4872039 IC50 7.0 nM
C[C@]1([C@H](O)C[C@H]2c3c(F)cccc3-c3cncn32)CC[C@H](O)CC1 CHEMBL5071087 IC50 7.0 nM
Cc1oc(C)c(-c2ccc(N(CC(C)C)CC(C)C)c(NC(=O)Nc3ccccc3F)c2)c1C(=O)O CHEMBL4535155 IC50 7.1 nM
CCN(c1ccc(-c2c(C)oc(C)c2C(=O)O)cc1NC(=O)Nc1ccccc1F)C1CCCCC1 CHEMBL4517780 IC50 7.4 nM
CCN(c1ccc(-c2c(C)oc(C)c2C(=O)O)cc1NC(=O)Nc1ccc(C)cc1)C1CCCCC1 CHEMBL4587368 IC50 7.5 nM
CS(=O)(=O)CCC(=O)NCCSc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL4436560 IC50 7.6 nM
CCN(c1ccc(-c2c(C)oc(C)c2C(=O)O)cc1NC(=O)Nc1ccc(F)cc1F)C1CCCCC1 CHEMBL4541125 IC50 7.8 nM
C[C@@H](NC(=O)c1ccc(Cl)cc1)c1cc2c(cn1)N(C(=O)c1cccc(Cl)c1)CCC2 CHEMBL4777831 IC50 7.8 nM
C[C@H](C(=O)Nc1ccc(Cl)cc1)[C@H]1CC[C@]2(CC1)COc1ncc(C(F)(F)F)cc12 CHEMBL4743724 IC50 7.9 nM
Cn1cc(-c2ccc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)cc2F)cn1 CHEMBL4445809 IC50 8.0 nM
O=C(Nc1ccc(Cl)cc1F)C(=O)N1CCCC(c2ccnc3ccc(F)cc23)CC1 CHEMBL4764848 IC50 8.0 nM
O=C(C1CC1)N1CCc2nc(C3(C(=O)Nc4ccc(F)cc4)CCC3)ccc21 CHEMBL4858232 IC50 8.0 nM
NS(=O)(=O)CC(=O)NCCSc1nonc1/C(=N/O)Nc1cccc(Br)c1 CHEMBL4441030 IC50 8.1 nM
Cc1nccc(N2c3ccc(C4(NC(=O)c5ccc(F)cc5)CC4)cc3[C@@H]3C[C@@H]32)n1 CHEMBL4869578 IC50 8.2 nM
CC(C(=O)Nc1ccc(Cl)cc1)C1CCC2(CC1)c1ccc(C(F)(F)F)cc1CN2C CHEMBL4764360 IC50 8.3 nM
CC(C)(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cc(F)c(F)cc43)C[C@@H]21 CHEMBL4845961 IC50 8.3 nM
CC(C)(O)CC(=O)NCCSc1nonc1/C(=N/O)Nc1ccc(F)c(C(F)F)c1 CHEMBL4521926 IC50 8.4 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4cccc(F)c4c3=O)C[C@@H]21 CHEMBL4848111 IC50 8.4 nM
CC[C@H](NC(=O)c1ccc(Cl)cc1)[C@@H]1[C@@H]2C[C@@H](n3cnc4ccc(F)cc43)C[C@@H]21 CHEMBL4871068 IC50 8.4 nM
Cc1oc(C)c(-c2ccc(N(CC(C)C)CC(C)C)c(NC(=O)Nc3ccc(F)cc3)c2)c1C(=O)O CHEMBL4578040 IC50 8.5 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cn[nH]c13)c1cc(OC)ccc1O2 CHEMBL4521139 IC50 8.7 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3cnc4ccc(C#N)cc43)C[C@@H]21 CHEMBL4848514 IC50 8.8 nM
CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3c1NC(=O)C3)c1cc(Br)ccc1O2 CHEMBL4529084 IC50 9.0 nM
O=C(Nc1ccc(Cl)cc1)C(=O)N1CCC(c2ccnc3ccc(F)cc23)C(F)(F)C1 CHEMBL4777262 IC50 9.0 nM
O=C(NCc1ccc2c(c1)CCCN2C(=O)c1cccc(Cl)c1)c1ccc(Cl)cc1 CHEMBL4791214 IC50 9.0 nM
CCCNC(=O)C1(c2ccc(NC(=O)c3cccc(Cl)c3)cc2)CCC1 CHEMBL4636709 IC50 9.0 nM
O=C(C[C@H]1CC[C@@H](c2ccccc2)CC1)Nc1ccc(Cl)cc1 CHEMBL4872488 IC50 9.1 nM
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@@H](n3c(C)nc4ccc(F)cc43)C[C@@H]21 CHEMBL4864639 IC50 9.2 nM
CS(=O)(=O)NCCSc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL4533342 IC50 9.3 nM
CCN(c1ccc(-c2c(C)oc(C)c2C(=O)O)cc1NC(=O)Nc1ccc(F)cc1)C1CCCCC1 CHEMBL4533465 IC50 9.6 nM
O[C@H](c1cc(Cl)cc2cncn12)C1CCCCC1 CHEMBL5203175 IC50 9.6 nM
O[C@@H](c1cn2cncc2cc1Cl)C1CCCCC1 CHEMBL5218853 IC50 9.6 nM
O[C@H](c1c(C2CC2)c(Cl)cc2cncn12)C1CC2CCC1CC2 CHEMBL5434107 IC50 9.6 nM
Cn1cc(-c2ccc(N3CCC([C@H]4c5c(F)cccc5-c5cncn54)CC3)cc2)cn1 CHEMBL4522927 IC50 9.7 nM
CCC(NC(=O)c1ccc(Cl)cc1)[C@H]1[C@@H]2C[C@H](Oc3ccnc4ccccc34)C[C@@H]21 CHEMBL4852532 IC50 9.9 nM