Cc1[nH]nc(N)c1-c1nc2cc(F)c(S(N)(=O)=O)cc2s1 CHEMBL3681007 IC50 7.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(N)(=O)=O)cc2s1 CHEMBL3681013 IC50 10.0 nM
NCCCc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685712 IC50 10.0 nM
CNCCCc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685682 IC50 20.0 nM
NCCNc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685727 IC50 20.0 nM
Nc1[nH]ncc1-c1nc2cc(F)c(S(N)(=O)=O)cc2s1 CHEMBL3639798 IC50 20.0 nM
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1 CHEMBL255863 Kd apparent 20.0 nM
CC(=O)NNS(=O)(=O)c1ccc2nc(-c3c(C)n[nH]c3N)sc2c1 CHEMBL3732995 IC50 30.0 nM
CNC(=O)c1cc(COc2nnc(Nc3ccc(Cl)cc3)c3ccoc23)ccn1 CHEMBL2079588 Kd apparent 32.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCc3ccncc3)cc2s1 CHEMBL3681027 IC50 40.0 nM
Cc1[nH]nc(N)c1-c1nc2c(F)cc(S(N)(=O)=O)cc2s1 CHEMBL3681005 IC50 40.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(F)ccc2s1 CHEMBL3685661 IC50 40.0 nM
COc1cc2sc(-c3c(-c4ccco4)n[nH]c3N)nc2cc1F CHEMBL3685652 IC50 40.0 nM
CNS(=O)(=O)c1cc2sc(-c3c(N)n[nH]c3C)nc2cc1F CHEMBL3680995 IC50 40.0 nM
Nc1[nH]nc(-c2ccncc2)c1-c1nc2ccc(S(N)(=O)=O)cc2s1 CHEMBL3685631 IC50 50.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(F)c(S(=O)(=O)NCCO)cc2s1 CHEMBL3681008 IC50 50.0 nM
Cc1cc2sc(-c3cn[nH]c3N)nc2cc1F CHEMBL3685659 IC50 50.0 nM
CNS(=O)(=O)c1ccc2nc(-c3cn[nH]c3N)sc2c1 CHEMBL3681004 IC50 60.0 nM
Nc1n[nH]c(C2CCNCC2)c1-c1nc2ccccc2s1 CHEMBL3685693 IC50 60.0 nM
COc1cc2sc(-c3c(N)n[nH]c3C)nc2cc1F CHEMBL3685654 IC50 60.0 nM
COC(=O)c1cc2sc(-c3c(N)n[nH]c3C)nc2cc1F CHEMBL3680994 IC50 60.0 nM
CNS(=O)(=O)c1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3680998 IC50 70.0 nM
COc1cc2sc(-c3c(N)n[nH]c3N3CCNCC3)nc2cc1F CHEMBL3685656 IC50 70.0 nM
Cc1[nH]nc(N)c1-c1nc2c(F)c(F)c(F)c(S(N)(=O)=O)c2s1 CHEMBL3680993 IC50 70.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCC(F)(F)F)cc2s1 CHEMBL3681024 IC50 90.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(CNCCO)cc2s1 CHEMBL3685634 IC50 100.0 nM
CNCCCCc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685684 IC50 100.0 nM
Nc1[nH]nc(-c2ccco2)c1-c1nc2ccccc2s1 CHEMBL3685688 IC50 100.0 nM
Nc1[nH]nc(-c2ccncc2)c1-c1nc2ccccc2s1 CHEMBL3685695 IC50 100.0 nM
COc1cc2sc(-c3c(-c4ccno4)n[nH]c3N)nc2cc1F CHEMBL3685653 IC50 100.0 nM
Nc1ccc(-c2n[nH]c(N)c2-c2nc3ccccc3s2)cc1 CHEMBL3685713 IC50 100.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(F)c(CO)cc2s1 CHEMBL3680988 IC50 100.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(F)c(S(=O)(=O)NCc3ccncc3)cc2s1 CHEMBL3681009 IC50 130.0 nM
Cc1[nH]nc(N)c1-c1nc2c(S(=O)(=O)NCCO)c(F)ccc2s1 CHEMBL3681006 IC50 150.0 nM
CCNCCNc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685701 IC50 150.0 nM
Nc1n[nH]c(N2CCNCC2)c1-c1nc2ccccc2s1 CHEMBL3685692 IC50 190.0 nM
Nc1n[nH]c(CCCO)c1-c1nc2ccccc2s1 CHEMBL3685635 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCCc3cnc[nH]3)cc2s1 CHEMBL3681025 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCCc3ccc(N)cc3)cc2s1 CHEMBL3681022 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCCO)cc2s1 CHEMBL3681014 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(O)ccc2s1 CHEMBL3681010 IC50 200.0 nM
CN(C)CCCc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685681 IC50 200.0 nM
COc1ccc2nc(-c3c(N)n[nH]c3N3CCNCC3)sc2c1 CHEMBL3685673 IC50 200.0 nM
Nc1[nH]ncc1-c1nc2ccc(F)cc2s1 CHEMBL3685669 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(CN(C)C)cc2s1 CHEMBL3685668 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(F)c(Br)cc2s1 CHEMBL3685664 IC50 200.0 nM
COc1cc2sc(-c3c(N)n[nH]c3NCCc3cnc[nH]3)nc2cc1F CHEMBL3685658 IC50 200.0 nM
COc1cc2sc(-c3c(-c4ccncc4)n[nH]c3N)nc2cc1F CHEMBL3685657 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2c(F)c(F)c(F)cc2s1 CHEMBL3685715 IC50 200.0 nM
COc1cc2sc(-c3c(N)n[nH]c3NCCCN(C)C)nc2cc1F CHEMBL3685729 IC50 200.0 nM
c1ccc2sc(-c3cn[nH]c3NCCc3cnc[nH]3)nc2c1 CHEMBL3680986 IC50 200.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCCN(C)C)cc2s1 CHEMBL3685628 IC50 300.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(C(N)=O)cc2s1 CHEMBL3681012 IC50 300.0 nM
Nc1[nH]ncc1-c1nc2ccccc2s1 CHEMBL3685679 IC50 300.0 nM
Cc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685689 IC50 300.0 nM
CN(C)CCCNc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685704 IC50 300.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(Cl)cc2s1 CHEMBL3685666 IC50 300.0 nM
Cc1cc2sc(-c3c(N)n[nH]c3C)nc2cc1F CHEMBL3685660 IC50 300.0 nM
COc1cc2sc(-c3c(-c4ccc([N+](=O)[O-])o4)n[nH]c3N)nc2cc1F CHEMBL3685651 IC50 300.0 nM
COc1cc2sc(-c3c(N)n[nH]c3NCCN(C)C)nc2cc1F CHEMBL3685728 IC50 300.0 nM
COC(=O)c1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3680997 IC50 300.0 nM
COc1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3685672 IC50 340.0 nM
Cc1[nH]nc(N)c1-c1nc2c(F)cccc2s1 CHEMBL3685641 IC50 400.0 nM
Nc1n[nH]c(NCCCO)c1-c1nc2ccccc2s1 CHEMBL3685636 IC50 400.0 nM
Nc1n[nH]c(NCCO)c1-c1nc2ccccc2s1 CHEMBL3685632 IC50 400.0 nM
CN(C)CCCCc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685683 IC50 400.0 nM
COc1c(F)cc2nc(-c3c(N)n[nH]c3C)sc2c1Cl CHEMBL3685676 IC50 400.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(F)cc2s1 CHEMBL3685670 IC50 400.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(Br)cc2s1 CHEMBL3685665 IC50 400.0 nM
CC(=O)Nc1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3685722 IC50 400.0 nM
COc1cc2sc(-c3c(N)n[nH]c3NCCCO)nc2cc1F CHEMBL3685637 IC50 500.0 nM
Nc1ccc2nc(-c3cn[nH]c3N)sc2c1 CHEMBL3681003 IC50 500.0 nM
CN(C)CCNc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685700 IC50 500.0 nM
Nc1n[nH]c(NCCCn2ccnc2)c1-c1nc2ccccc2s1 CHEMBL3685705 IC50 500.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(C)(=O)=O)cc2s1 CHEMBL3685671 IC50 500.0 nM
CNCc1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3685717 IC50 500.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(CN3CCOCC3)cc2s1 CHEMBL3685718 IC50 500.0 nM
NS(=O)(=O)c1ccc2nc(-c3cn[nH]c3)sc2c1 CHEMBL3680992 IC50 500.0 nM
CNC(=O)CCc1cc(-c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)n(-c2ccc(N3CCNCC3)cc2)n1 CHEMBL1830587 IC50 600.0 nM
COc1ccc2nc(-c3c(N)n[nH]c3NCCc3cnc[nH]3)sc2c1 CHEMBL3685731 IC50 600.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCc3ccc(N)cc3)cc2s1 CHEMBL3681026 IC50 600.0 nM
COCCNS(=O)(=O)c1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3681015 IC50 600.0 nM
Nc1n[nH]c(C2CC2)c1-c1nc2ccccc2s1 CHEMBL3685686 IC50 600.0 nM
Nc1[nH]nc(-c2cccnc2)c1-c1nc2ccccc2s1 CHEMBL3685694 IC50 600.0 nM
Cc1[nH]nc(N)c1-c1nc2cc(F)c(CN(C)C)cc2s1 CHEMBL3685667 IC50 600.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCC3CC3)cc2s1 CHEMBL3685732 IC50 700.0 nM
COC(=O)c1cccc2nc(-c3c(N)n[nH]c3C)sc12 CHEMBL3681000 IC50 700.0 nM
Nc1n[nH]c(N)c1-c1nc2ccccc2s1 CHEMBL3685680 IC50 700.0 nM
COCCNc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685702 IC50 700.0 nM
COc1cc2sc(-c3c(-c4cccs4)n[nH]c3N)nc2cc1F CHEMBL3685733 IC50 700.0 nM
CC(=O)NCCNS(=O)(=O)c1ccc2nc(-c3c(N)n[nH]c3C)sc2c1 CHEMBL3685725 IC50 700.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(CNc3cccc(S(N)(=O)=O)c3)cc2s1 CHEMBL3685638 IC50 800.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCCc3ccccc3)cc2s1 CHEMBL3681021 IC50 800.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCc3ccccc3)cc2s1 CHEMBL3681020 IC50 800.0 nM
CCc1[nH]nc(N)c1-c1nc2ccccc2s1 CHEMBL3685687 IC50 800.0 nM
COc1cc2sc(-c3c(-c4cccc([N+](=O)[O-])c4)n[nH]c3N)nc2cc1F CHEMBL3685648 IC50 900.0 nM
Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)NNc3ccccc3)cc2s1 CHEMBL3730049 IC50 900.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NCc3ccc(Cl)cc3)cc2s1 CHEMBL3681018 IC50 900.0 nM
Cc1[nH]ncc1-c1nc2ccccc2s1 CHEMBL3681001 IC50 900.0 nM
Nc1[nH]nc(-c2ccccc2)c1-c1nc2ccccc2s1 CHEMBL3685691 IC50 900.0 nM
Nc1[nH]nc(-c2cccs2)c1-c1nc2ccccc2s1 CHEMBL3685697 IC50 900.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(CN3CCCC3)cc2s1 CHEMBL3685719 IC50 900.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(CO)cc2s1 CHEMBL3680990 IC50 900.0 nM
Cc1[nH]nc(N)c1-c1nc2ccc(S(=O)(=O)NNNc3ccccc3)cc2s1 CHEMBL3685630 IC50 900.0 nM
NC(=O)c1nnsc1Nc1ccccc1 CHEMBL3730447 IC50 1000.0 nM
Nc1n[nH]c(CCCCO)c1-c1nc2ccccc2s1 CHEMBL3685642 IC50 1000.0 nM
COc1ccc(CNS(=O)(=O)c2ccc3nc(-c4c(N)n[nH]c4C)sc3c2)cc1 CHEMBL3681019 IC50 1000.0 nM
Nc1[nH]nc(/N=C/c2ncc[nH]2)c1-c1nc2ccccc2s1 CHEMBL3685699 IC50 1000.0 nM
COc1ccc(Cl)c2sc(-c3c(N)n[nH]c3C)nc12 CHEMBL3685675 IC50 1000.0 nM
COc1cc2sc(-c3c(N)n[nH]c3C3CC3)nc2cc1F CHEMBL3685714 IC50 1000.0 nM