CS(=O)(=O)Nc1cccc([C@H](c2ccc(F)cc2)C(c2cccnc2)c2cccnc2)n1 CHEMBL4065169 IC50 9.0 nM
COc1ccc(OCCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 CHEMBL3961395 EC50 10.0 nM
O=c1ccc2c(OCCCCOc3ccc(Cl)cc3)c3ccoc3cc2o1 CHEMBL3940526 EC50 10.0 nM
O[C@@H](c1cccnc1-c1cc(Cl)cc(Cl)c1)C(c1cccnc1)c1cccnc1 CHEMBL4104525 IC50 11.0 nM
O=c1ccc2c(OCCCCOc3ccc(F)cc3)c3ccoc3cc2o1 CHEMBL3960875 EC50 12.0 nM
CC1=C(c2nc3cc(F)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL571976 IC50 15.0 nM
Cc1ccc(OCCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 CHEMBL3899148 EC50 20.0 nM
CCc1c2c(n(C)c1CC)CCC/C2=N\OC(=O)Nc1ccccc1 CHEMBL216281 IC50 21.0 nM
COc1cccc2ccnc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298226 IC50 22.0 nM
COc1cccc2nc(O)nc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298228 IC50 23.0 nM
Clc1ccccc1-c1ncccc1CC(c1cccnc1)c1cccnc1 CHEMBL4085436 IC50 23.0 nM
COc1cccc2snc(NCC(C)(C)c3ccccc3)c12 CHEMBL3356073 IC50 24.0 nM
O=c1ccc2c(OCCCOc3ccc(F)cc3)c3ccoc3cc2o1 CHEMBL3930613 EC50 25.0 nM
Clc1ccccc1-c1ncccc1CC(c1cccnc1)c1cccnc1Cl CHEMBL4105245 IC50 26.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](NC(=O)OCC(F)(F)F)CC1)=NS2(=O)=O CHEMBL3622361 IC50 28.0 nM
COCC1=C(c2nc3cc(F)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL567671 IC50 30.0 nM
CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1P(=O)(c1ccccc1)c1ccccc1 CHEMBL1088844 IC50 30.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](OC(=O)Nc3ccc(N(C)C)cc3)CC1)=NS2(=O)=O CHEMBL3622355 IC50 30.0 nM
Clc1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4062996 IC50 30.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](n3cnnn3)CC1)=NS2(=O)=O CHEMBL3623054 IC50 32.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3C[C@H]2O)cc1 CHEMBL288131 IC50 33.0 nM
FC(F)(F)Oc1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4075394 IC50 33.0 nM
COc1cccc2c1C(NCC(C)(C)c1ccccc1)=NC2=O CHEMBL3356074 IC50 34.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](O)CC1)=NS2(=O)=O CHEMBL3622346 IC50 34.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)CCc1ccccc1F)c1ccccc1)C(C)C CHEMBL385809 IC50 36.0 nM
CC1=C(c2ncnn2C2CCCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331989 IC50 37.0 nM
c1ccc(-c2cccc3nc(-c4ccncc4)nc(NCc4ccccn4)c23)cc1 CHEMBL4521294 IC50 40.0 nM
COc1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4095750 IC50 41.0 nM
COc1cccc2onc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298140 IC50 43.0 nM
O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1 CHEMBL444449 EC50 45.0 nM
COc1cccc(OCCCCOc2c3ccoc3cc3oc(=O)ccc23)c1 CHEMBL3899683 EC50 45.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2CCCc3ccc(N(Cc4cccc(C)n4)C(=O)CCc4ccccc4)cc32)cc1 CHEMBL260684 IC50 46.0 nM
NS(=O)(=O)c1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1 CHEMBL4094440 IC50 46.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](Nc3ncccn3)CC1)=NS2(=O)=O CHEMBL3623053 IC50 47.0 nM
CCCn1c(C2=C(C)Nc3ccnn3C2c2ccc(Cl)c(Cl)c2)nc2cc(F)ccc21 CHEMBL567235 IC50 48.0 nM
CC1=C(c2ncnn2C2CCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331990 IC50 48.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2ccc(F)cc2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL602070 IC50 50.0 nM
O=c1ccc2c(OCCCCOc3cccc4ccccc34)c3ccoc3cc2o1 CHEMBL3958206 EC50 50.0 nM
c1ccc(-c2cccc3nc(-c4cncs4)nc(NCc4ccccn4)c23)cc1 CHEMBL4532101 IC50 50.0 nM
N#Cc1nc(NCc2ccccn2)c2c(-c3ccccc3)cccc2n1 CHEMBL4450487 IC50 50.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](NC(=O)OC(C)C)CC1)=NS2(=O)=O CHEMBL3622360 IC50 52.0 nM
CCN(CC)S(=O)(=O)N[C@H]1CC[C@](CNC2=NS(=O)(=O)c3cccc(OC)c32)(c2ccccc2)CC1 CHEMBL3623052 IC50 52.0 nM
CCc1ccc(OCCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 CHEMBL3982686 EC50 52.0 nM
CCOC(=O)N[C@H]1CC[C@](CNC2=NS(=O)(=O)c3cccc(OC)c32)(c2ccccc2)CC1 CHEMBL3622358 IC50 55.0 nM
Nc1cccc(C(Cc2cccnc2-c2cccc(C(F)(F)F)c2)c2cccnc2)n1 CHEMBL4088894 IC50 56.0 nM
CCCCN([C@@H]1c2cc(C(=O)NCCc3ccccc3)ccc2OC(C)(C)[C@H]1O)S(=O)(=O)c1ccc(CC)cc1 CHEMBL230671 IC50 57.0 nM
CCn1c(C2=C(C)Nc3ccnn3C2c2ccc(Cl)c(Cl)c2)nc2cc(Cl)ccc21 CHEMBL567244 IC50 57.0 nM
CC1=C(c2ncnn2C2CCCCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331987 IC50 59.0 nM
COc1ccc2c(C(=O)NCCO)nc(C#N)c(-c3ccccc3)c2c1 CHEMBL214578 IC50 60.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N4CCC[C@H]4CNc4c(C)cccc4C)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL387993 IC50 60.0 nM
CCS(=O)(=O)N[C@H]1CC[C@](CNC2=NS(=O)(=O)c3cccc(OC)c32)(c2ccccc2)CC1 CHEMBL3622362 IC50 60.0 nM
CCc1ccc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 CHEMBL3943702 EC50 60.0 nM
c1ccc(-c2cccc3nc(-c4cccnc4)nc(NCc4ccccn4)c23)cc1 CHEMBL4099807 IC50 60.0 nM
CCCN(CCC)[C@H](c1ccccn1)[C@@H](c1ccccn1)N(CCC)C[C@H](O)CO CHEMBL4475999 IC50 60.0 nM
Nc1cccc(C(Cc2cccnc2-c2cc(Cl)cc(Cl)c2)c2cccnc2)n1 CHEMBL4067665 IC50 62.0 nM
CC1=C(c2nc3c(F)cccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL565312 IC50 64.0 nM
CN(C)C(=O)c1cccc(-c2ccccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4100226 IC50 64.0 nM
c1cncc(-c2ccccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4097667 IC50 64.0 nM
CCNC(=O)O[C@H]1CC[C@](CNC2=NS(=O)(=O)c3cccc(OC)c32)(c2ccccc2)CC1 CHEMBL3622348 IC50 65.0 nM
Cc1ccc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 CHEMBL3922127 EC50 65.0 nM
CCc1c(C)[nH]c2c1/C(=N/OC(=O)Nc1ccccc1)CCC2 CHEMBL217347 IC50 67.0 nM
CC1=C(c2nc3cc(Cl)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL566382 IC50 68.0 nM
O=c1ccc2c(OCCCOc3cccc(C(F)(F)F)c3)c3ccoc3cc2o1 CHEMBL3928866 EC50 68.0 nM
COc1ccc(CCN2C(=O)CSC2(C)c2ccc(C)c(C)c2)cc1 CHEMBL384197 IC50 69.0 nM
CCCN(CCC)C(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL480807 IC50 70.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL482381 IC50 70.0 nM
CCCCCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3CC[C@H]2O)cc1 CHEMBL468514 IC50 70.0 nM
CC1=C(C(=O)N2CCCC2c2ccc(F)cc2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL605576 IC50 70.0 nM
COCC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2042152 IC50 70.0 nM
Clc1nc(NCc2ccccn2)c2c(-c3ccccc3)cccc2n1 CHEMBL4483629 IC50 70.0 nM
CC1=C(c2nc3cccc(Cl)c3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL566800 IC50 71.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2cc3ccccc3n2C)n2nc(C(F)(F)F)cc2N1 CHEMBL2042162 IC50 72.0 nM
COc1cccc2nc(Cl)nc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298227 IC50 73.0 nM
CC1=C(c2ncnn2-c2ccccc2F)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2332455 IC50 74.0 nM
CC1=C(c2nc3ccccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL577300 IC50 75.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)CCNc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL228330 IC50 77.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)n4nc(-c5ccccc5)cc4N)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL388762 IC50 79.0 nM
O=P(NCc1cccnc1-c1cc(Cl)cc(Cl)c1)(c1ccccc1)c1ccccc1 CHEMBL2312931 IC50 80.0 nM
CC1=C(c2ncnn2-c2ccc(C)cc2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2332457 IC50 80.0 nM
O=c1ccc2c(OCCCCOc3ccc4ccccc4c3)c3ccoc3cc2o1 CHEMBL3985258 EC50 80.0 nM
O=S(=O)(c1cccc(Nc2nc(-c3cncnc3)nc3cccc(-c4ccccc4)c23)c1)N1CCOCC1 CHEMBL4082779 IC50 80.0 nM
FC(F)(F)c1nc(NCc2ccccn2)c2c(-c3ccccc3)cccc2n1 CHEMBL4521058 IC50 80.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2042156 IC50 83.0 nM
FC(F)(F)c1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4100098 IC50 84.0 nM
OC(Cc1cccnc1-c1cc(Cl)cc(Cl)c1)(c1cccnc1)c1cccnc1 CHEMBL4094177 IC50 84.0 nM
CC1=C(C(=O)N2CCN(c3ccccc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL517078 IC50 85.0 nM
COc1cccc(-n2ncnc2C2=C(C)Nc3cc(C(F)(F)F)nn3[C@@H]2c2ccc(Cl)c(Cl)c2)n1 CHEMBL2332448 IC50 87.0 nM
CCNC(=O)O[C@H]1CC[C@](CNc2nn(C)c3cccc(OC)c23)(c2ccccc2)CC1 CHEMBL3298231 IC50 88.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2c3cc(C(=O)N4CCC[C@@H]4CNc4c(C)cccc4C)ccc3OC(C)(C)[C@@H]2O)cc1 CHEMBL228808 IC50 89.0 nM
CC1=C(c2ncnn2C(C)C)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331986 IC50 89.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](OC(=O)NCCC(F)(F)F)CC1)=NS2(=O)=O CHEMBL3622350 IC50 89.0 nM
CC1=C(C(=O)N2CCCCC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL465277 IC50 90.0 nM
CCCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3CC[C@H]2O)cc1 CHEMBL466838 IC50 90.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)on2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL602854 IC50 90.0 nM
CN(c1cccnc1)c1ncccc1CC(c1cccnc1)c1cccnc1 CHEMBL4080304 IC50 90.0 nM
c1ccc(-c2cccc3nc(-c4cncnc4)nc(NCc4ccccn4)c23)cc1 CHEMBL4097255 IC50 90.0 nM
Cc1noc(C)c1-c1nc(NCc2ccccn2)c2c(-c3ccccc3)cccc2n1 CHEMBL4576889 IC50 90.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](OC(=O)Nc3nnc(C4CC4)s3)CC1)=NS2(=O)=O CHEMBL3622351 IC50 92.0 nM
CC(CC(=O)NCC(c1ccccc1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1)c1ccccc1 CHEMBL216955 IC50 94.0 nM
CC1=C(c2nc3cc(Cl)ccc3n2C(C)C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL585123 IC50 94.0 nM
CC1=C(c2ncnn2C2CCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2331996 IC50 94.0 nM
COc1ccc(CON2C(=O)CSC2c2ccc(C)c(C)c2)cc1 CHEMBL386802 IC50 95.0 nM
CC1=C(c2ncnn2-c2cccc(C(F)(F)F)n2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332443 IC50 96.0 nM
CC1=C(c2ncnn2-c2cccc(F)c2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2332454 IC50 97.0 nM
CCOCCn1ccnc1C1=C(C)Nc2cc(C(F)(F)F)nn2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL2332452 IC50 98.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)CCc1ccccc1)c1ccccc1)C(C)C CHEMBL217222 IC50 100.0 nM
CC1=C(C(=O)NCCc2ccccc2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL517791 IC50 100.0 nM
COc1ccc(CCCN2C(=O)N(NS(C)(=O)=O)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL583430 IC50 100.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2ccc(F)cc2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2042154 IC50 100.0 nM
O=P(c1ccccc1)(c1ccccc1)C(c1ccccc1)c1cccnc1 CHEMBL2312926 IC50 100.0 nM
O=c1ccc2c(OCCCOc3ccccc3)c3ccoc3cc2o1 CHEMBL3906400 EC50 100.0 nM
COc1ccc2sc(SCCCCOc3c4ccoc4cc4oc(=O)ccc34)nc2c1 CHEMBL3901865 EC50 100.0 nM
COc1ncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cn1 CHEMBL4061436 IC50 100.0 nM
NC(=O)c1ccc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cn1 CHEMBL4072025 IC50 100.0 nM
CC(=O)Nc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1 CHEMBL4068539 IC50 100.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2042158 IC50 101.0 nM
CCCn1ncnc1C1=C(C)Nc2ccnn2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL2331985 IC50 102.0 nM
CC1=C(c2ncnn2CCCC(F)(F)F)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331994 IC50 103.0 nM
O=c1ccc2c(OCCCCOc3ccc([N+](=O)[O-])cc3)c3ccoc3cc2o1 CHEMBL3937779 EC50 105.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2CC(C)(C)Oc3ccc(C(=O)N4CCC[C@H]4CNc4c(C)cccc4C)cc32)cc1 CHEMBL228809 IC50 110.0 nM
CC1=C(c2nc3cccc(C)c3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL569269 IC50 110.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL601641 IC50 110.0 nM
O=c1ccc2c(OCCOCc3ccccc3)c3ccoc3cc2o1 CHEMBL3953745 EC50 110.0 nM
OC(c1cccnc1-c1cccc(Cl)c1Cl)C(c1cccnc1)c1cccnc1 CHEMBL4097545 IC50 110.0 nM
Oc1ccc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cn1 CHEMBL4081790 IC50 110.0 nM
COC(=O)CC(c1cccc(-c2c(C)noc2C)c1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1 CHEMBL386441 IC50 113.0 nM
COc1ccc(CON2C(=O)CSC2c2ccc(Cl)c(Cl)c2)cc1 CHEMBL387066 IC50 113.0 nM
CC1=C(c2ncnn2-c2ccc(F)cc2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2332453 IC50 115.0 nM
COc1ccccc1-n1ncnc1C1=C(C)Nc2ccnn2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL2332456 IC50 116.0 nM
CN(C)C(=O)c1cccc(-c2ccc(F)cc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4094185 IC50 116.0 nM
COc1cccc2ncnc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298225 IC50 118.0 nM
COc1ccc2c(=O)n(CC(CO)NCc3cccnc3)c(C#N)c(-c3ccccc3)c2c1 CHEMBL214553 IC50 120.0 nM
CCc1ccc(S(=O)(=O)N(Cc2ccccn2)[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL230238 IC50 120.0 nM
CCc1ccc(S(=O)(=O)N(CC(C)(C)C)[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL230776 IC50 120.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL464077 IC50 120.0 nM
CCCN(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2312933 IC50 120.0 nM
COc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1 CHEMBL4449766 IC50 120.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2042147 IC50 124.0 nM
CC1=C(c2ncnn2C2CCCCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2331997 IC50 127.0 nM
CCn1ccnc1C1=C(C)Nc2cc(C(F)(F)F)nn2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL2332450 IC50 128.0 nM
CCc1c(C)[nH]c2c1/C(=N/NC(=O)Nc1ccccc1)CCC2 CHEMBL217133 IC50 130.0 nM
CCc1c(C)[nH]c2c1/C(=N/N(C)C(=O)Nc1ccc(Cl)cc1)CCC2 CHEMBL216624 IC50 130.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N4CCC[C@@H]4CNc4c(C)cccc4C)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL230251 IC50 130.0 nM
CCc1ccc(S(=O)(=O)N(Cc2cccnc2)[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL230564 IC50 130.0 nM
N#Cc1ccc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cn1 CHEMBL4437080 IC50 130.0 nM
CC1=C(c2ncnn2C2CCC(C(F)(F)F)CC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2331983 IC50 133.0 nM
c1cncc(C(Cc2ccccc2-c2cncc3ccccc23)c2cccnc2)c1 CHEMBL4079636 IC50 133.0 nM
CC1=C(c2ncnn2Cc2ccccc2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2332465 IC50 135.0 nM
N#Cc1cccc(-c2cc(F)ccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4068841 IC50 136.0 nM
COC1=CCC(CCN2C(=O)CSC2c2ccc(C)c(C)c2)C=C1 CHEMBL445586 IC50 137.0 nM
COC(=O)CC(c1cccc(Br)c1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1 CHEMBL217011 IC50 137.0 nM
COc1ccc(CCN2C(=O)CSC2c2ccc(C)c(C)c2)cc1 CHEMBL289939 IC50 137.0 nM
Cc1cc(F)ccc1-c1ccccc1C(C#N)C(c1cccnc1)c1cccnc1 CHEMBL4072707 IC50 137.0 nM
CCNC(=O)O[C@H]1CC[C@](CNc2n[nH]c3cccc(OC)c23)(c2ccccc2)CC1 CHEMBL3298232 IC50 138.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cc(Cl)cc(Cl)c2)n2nccc2N1 CHEMBL465124 IC50 140.0 nM
CCCCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3CC[C@H]2O)cc1 CHEMBL42934 IC50 140.0 nM
O=P(c1ccccc1)(c1ccccc1)C(c1cccnc1)N1CCCCC1 CHEMBL2312927 IC50 140.0 nM
COC(=O)CC(c1cccnc1)C(C(=O)N(C(C)C)C(C)C)c1cccc(Br)c1 CHEMBL217921 IC50 147.0 nM
CC(=O)NC(c1ccccc1-c1cc(Cl)cc(Cl)c1)C(c1cccnc1)c1cccnc1 CHEMBL4081003 IC50 148.0 nM
CC1=C(C(=O)N2CCN(c3ccccc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2042148 IC50 149.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1ccccc1F)c1ccccc1)C(C)C CHEMBL217620 IC50 150.0 nM
COc1ccc(CCC(=O)N2CCSC2c2ccc(C)c(C)c2)cc1 CHEMBL262209 IC50 150.0 nM
CC1(C)Oc2ccc(C(=O)NCCc3ccccc3)cc2[C@@H](NS(=O)(=O)c2ccccc2OC(F)(F)F)[C@@H]1O CHEMBL228493 IC50 150.0 nM
CCc1ccc(S(=O)(=O)NC2CCc3ccc(NC(=O)c4cccc(OC)c4)cc32)cc1 CHEMBL239805 IC50 150.0 nM
CC1=C(c2nc3cccc(C)c3[nH]2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL583857 IC50 150.0 nM
CC1=C(c2nc3cccc(F)c3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL584709 IC50 150.0 nM
CC1=C(C(=O)N2CCCC2c2ccccc2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL605992 IC50 150.0 nM
COC(=O)[C@@H]1CCCN1C(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL603705 IC50 150.0 nM
COCC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2cc3ccccc3n2C)n2nc(C(F)(F)F)cc2N1 CHEMBL2042163 IC50 150.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccccc4c3=O)Cc3ccc(C#N)cc3)ccc21 CHEMBL3729229 IC50 150.0 nM
COc1cc(OC)cc(OCCCCOc2c3ccoc3cc3oc(=O)ccc23)c1 CHEMBL3902465 EC50 150.0 nM
FC(F)(F)c1ccc(-c2cccc3nc(-c4cncnc4)nc(NCc4ccccn4)c23)cc1 CHEMBL4441178 IC50 150.0 nM
CC1=C(c2ncnn2CCC(F)(F)F)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331993 IC50 151.0 nM
Nc1cccc(C(c2cccnc2)C(O)c2cccnc2-c2cc(Cl)cc(Cl)c2)n1 CHEMBL4102309 IC50 153.0 nM
CC1=C(C(=O)N2CCC(c3ccccc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL479618 IC50 159.0 nM
O=c1ccc2c(OCCCCSc3ncccn3)c3ccoc3cc2o1 CHEMBL3953466 EC50 159.0 nM
C[C@H](OC(=O)NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)c1ccccc1 CHEMBL317791 IC50 160.0 nM
COc1ccc2c(OC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1 CHEMBL383997 IC50 160.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cc3ccccc3o2)n2nccc2N1 CHEMBL521104 IC50 160.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cccc(Cl)c2Cl)n2nccc2N1 CHEMBL464066 IC50 160.0 nM
CC1=C(C(=O)NCc2ccccc2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL465086 IC50 160.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)[C@@H](c2cccc(Cl)c2Cl)n2nccc2N1 CHEMBL480020 IC50 160.0 nM
COc1cccc(C(=O)Nc2ccc3c(c2)[C@@H](NS(=O)(=O)c2ccc(C(C)(C)C)cc2)[C@H](O)CC3)c1 CHEMBL466019 IC50 160.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(C3CC3)cc2)cc1 CHEMBL583254 IC50 160.0 nM
CC1=C(C(=O)N2CCC(c3ccc(F)cc3)C2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL601672 IC50 160.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2nc(C)no2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL600211 IC50 160.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccoc4c3=O)Cc3ccc(C#N)cc3)ccc21 CHEMBL3729998 IC50 160.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3cccc(C#N)c3)ccc21 CHEMBL3731401 IC50 160.0 nM
c1ccc(-c2cccc3nc(-c4cn[nH]c4)nc(NCc4ccccn4)c23)cc1 CHEMBL4443183 IC50 160.0 nM
CN(C)C(=O)c1cccc(-c2ncccc2CC(c2ccnc(N)n2)c2cccnc2F)c1 CHEMBL4080956 IC50 161.0 nM
Cc1ccc(C2SCCN2C(=O)COc2ccccc2)cc1C CHEMBL217372 IC50 162.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2042157 IC50 165.0 nM
CC1=C(c2ncnn2C2CCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2331999 IC50 165.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)[C@H]4CCN(Cc5ccccc5)C4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL389096 IC50 170.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)Cc4ccccc4F)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL228277 IC50 170.0 nM
CC1=C(C(=O)Nc2ccccc2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL465085 IC50 170.0 nM
COc1cccc2c1C(NC[C@]1(c3ccccc3)CC[C@H](OC(=O)NC3CC3)CC1)=NS2(=O)=O CHEMBL3622349 IC50 170.0 nM
O=c1ccc2c(OCCCOCc3ccccc3)c3ccoc3cc2o1 CHEMBL3959937 EC50 170.0 nM
c1ccc(-c2cccc3nc(C4CC4)nc(NCc4ccccn4)c23)cc1 CHEMBL4590051 IC50 170.0 nM
OC(c1cccnc1-c1ccccc1Cl)C(c1cccnc1)c1cccnc1 CHEMBL4061731 IC50 171.0 nM
COc1ccccc1CON1C(=O)CSC1c1ccc(C)c(C)c1 CHEMBL424912 IC50 177.0 nM
COc1cccc(CON2C(=O)CSC2c2ccc(Cl)c(Cl)c2)c1 CHEMBL387102 IC50 179.0 nM
COc1ccc(CCn2nnn[n+]2C2(c3ccc(C)c(C)c3)CC2)cc1 CHEMBL424735 IC50 180.0 nM
O=P(c1ccccc1)(c1ccccc1)C(c1cccnc1)c1cccnc1 CHEMBL2312925 IC50 180.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccoc4c3=O)Cc3cccs3)ccc21 CHEMBL3732734 IC50 180.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccccc3-c3cccnc3)ccc21 CHEMBL3727564 IC50 180.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccccc4c3=O)Cc3ccncc3)ccc21 CHEMBL3733073 IC50 180.0 nM
COC(=O)CC(c1cccc(C#N)c1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1 CHEMBL385737 IC50 184.0 nM
COc1ccc(CON2C(=O)CSC2c2ccc(Cl)cc2)cc1 CHEMBL218185 IC50 187.0 nM
COc1cccc2onc(N(C)CC(C)(C)c3ccccc3)c12 CHEMBL3298147 IC50 187.0 nM
COc1ccc2c(=O)n(C)c(CN(C)C)c(-c3ccccc3)c2c1 CHEMBL214742 IC50 190.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cccc(Cl)c2)n2nccc2N1 CHEMBL465930 IC50 190.0 nM
CC1=C(C(=O)N2CCCCCC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL518718 IC50 190.0 nM
CC1=C(c2ncnn2-c2cccc(Cl)n2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332444 IC50 190.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccoc4c3=O)Cc3ccc(C(F)(F)F)cc3)ccc21 CHEMBL3729852 IC50 190.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccccc4c3=O)Cc3ccsc3)ccc21 CHEMBL3729291 IC50 190.0 nM
CCn1ncnc1C1=C(C)Nc2ccnn2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL2331984 IC50 191.0 nM
OC(Cc1cccnc1-c1cccc(C(F)(F)F)c1)(c1cccnc1F)c1cccnc1F CHEMBL4084347 IC50 195.0 nM
COc1cccc2oc(=O)nc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298229 IC50 197.0 nM
COc1cccc2c1c(NCC(C)(C)c1ccccc1)nn2C CHEMBL3356070 IC50 198.0 nM
CCc1c(C)[nH]c2c1/C(=N/NC(=S)Nc1cccc(C(F)(F)F)c1)CCC2 CHEMBL217668 IC50 200.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2c3cc(C(=O)N(CC)[C@H]4CCN(Cc5ccccc5)C4)ccc3OC(C)(C)[C@@H]2O)cc1 CHEMBL438665 IC50 200.0 nM
CC1(C)Oc2ccc(C(=O)NCCc3ccccc3)cc2[C@@H](NS(=O)(=O)c2ccc(C(F)(F)F)cc2)[C@@H]1O CHEMBL390106 IC50 200.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3CCC[C@H]2O)cc1 CHEMBL239808 IC50 200.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2sc3ccccc3c2C)n2nccc2N1 CHEMBL481399 IC50 200.0 nM
COC[C@@H]1CCCN1C(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL520586 IC50 200.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)/C=C/c4ccccc4)ccc3CC[C@H]2O)cc1 CHEMBL467478 IC50 200.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(Cl)cc2)cc1 CHEMBL583465 IC50 200.0 nM
CC1=C(c2nc3cc(C)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL585923 IC50 200.0 nM
COC(=O)c1ccc2c(c1)nc(C1=C(C)Nc3ccnn3C1c1ccc(Cl)c(Cl)c1)n2C CHEMBL567234 IC50 200.0 nM
c1ccc([C@@H]([C@H](c2ccccc2)N2CCCCC2)N2CCCCC2)cc1 CHEMBL2152522 IC50 200.0 nM
c1ccc([C@H]([C@@H](c2ccccc2)N2CCCCC2)N2CCCCC2)cc1 CHEMBL2152523 IC50 200.0 nM
CCCN(c1cccc(C#N)c1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2312920 IC50 200.0 nM
CC1=C(c2ncnn2CC(F)(F)F)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331992 IC50 200.0 nM
COc1ccccc1CON1C(=O)CSC1c1ccc(Cl)c(Cl)c1 CHEMBL217828 IC50 204.0 nM
OC(c1ccccc1)(c1ccccc1)C(c1ccccc1)N1CCOCC1 CHEMBL1091863 IC50 204.0 nM
CC1=C(c2nccn2C(C)C)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332451 IC50 204.0 nM
OC(c1cccnc1)(c1cccnc1)C(c1ccccc1)N1CCCCC1 CHEMBL1090160 IC50 206.0 nM
Cc1ccc(C2SCC(=O)N2OCc2ccccc2)cc1C CHEMBL385641 IC50 207.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(Cl)cc2N1 CHEMBL2042151 IC50 209.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)[C@@H]4CCN(Cc5ccccc5)C4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL228813 IC50 210.0 nM
CN1C(=O)CC[C@H]1CN(Cc1ccc(Cl)cc1)S(=O)(=O)c1cccc(C#N)c1 CHEMBL3127404 IC50 210.0 nM
CN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccnc4ccccc34)ccc21 CHEMBL3729344 IC50 210.0 nM
O=S(=O)(c1cccc(Nc2nc(Cl)nc3cccc(-c4ccccc4)c23)c1)N1CCOCC1 CHEMBL4084636 IC50 210.0 nM
CC1=C(c2ncnn2-c2cccc(C)n2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332447 IC50 211.0 nM
COC(=O)CC(c1ccc(C#N)cc1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1 CHEMBL411970 IC50 215.0 nM
CCc1cccc2onc(NCC(C)(C)c3ccccc3)c12 CHEMBL3298145 IC50 219.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2c3cc(C(=O)N(CC)[C@@H]4CCN(Cc5ccccc5)C4)ccc3OC(C)(C)[C@@H]2O)cc1 CHEMBL389892 IC50 220.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)[C@H]4CCCN4Cc4cccc(Cl)c4)ccc3CC[C@H]2O)cc1 CHEMBL524191 IC50 220.0 nM
CC1=C(c2nc3cc(C#N)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL567025 IC50 220.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccoc4c3=O)Cc3ccccc3C)ccc21 CHEMBL3729497 IC50 220.0 nM
CCCN(CCC)[C@H](c1ccccn1)[C@@H](c1ccccn1)N(CCC)CCC CHEMBL4476275 IC50 220.0 nM
CCOc1cccc(-n2ncnc2C2=C(C)Nc3cc(C(F)(F)F)nn3[C@@H]2c2ccc(Cl)c(Cl)c2)n1 CHEMBL2332449 IC50 223.0 nM
CC1=C(c2ncnn2C(C)(C)C)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331988 IC50 223.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C3CC3)cc2N1 CHEMBL2042159 IC50 227.0 nM
CC1=C(c2ncnn2CC2CC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL2331991 IC50 229.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)s2)n2nccc2N1 CHEMBL480019 IC50 230.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)OCc4ccccc4)ccc3CC[C@H]2O)cc1 CHEMBL466646 IC50 230.0 nM
COc1ccc(CCN2C(=O)N(NS(=O)(=O)CC#N)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL570815 IC50 230.0 nM
OC(c1cccnc1-c1cc(Cl)cc(Cl)c1)C(c1cccnc1)c1ccccn1 CHEMBL4074029 IC50 233.0 nM
CCN(CC)C(c1ccccc1)C(O)(c1cccnc1)c1cccnc1 CHEMBL1091162 IC50 234.0 nM
Cc1ccc(CNC(=O)NCC(c2ccccc2)C(C(=O)N(C(C)C)C(C)C)c2cccnc2)cc1 CHEMBL217291 IC50 240.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(CNCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL387950 IC50 240.0 nM
CCc1ccc(S(=O)(=O)NCc2cccc(NC(=O)c3cccc(OC)c3)c2)cc1 CHEMBL241513 IC50 240.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(C)cc2)cc1 CHEMBL572153 IC50 240.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(OC(C)C)cc2)cc1 CHEMBL571952 IC50 240.0 nM
CC(C)(CNC(=O)C1(C(F)(F)F)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289186 IC50 240.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3c(=O)ccc4ccccc43)Cc3ccncc3)ccc21 CHEMBL3731066 IC50 240.0 nM
Cc1ccc(OCCCCOc2c3ccoc3cc3oc(=O)ccc23)c([N+](=O)[O-])c1 CHEMBL3894190 EC50 248.0 nM
CC(NC(=O)CC(c1ccccc1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1)c1ccccc1 CHEMBL218128 IC50 249.0 nM
COc1ccc2c(=O)n(CC(O)CO)c(C#N)c(-c3cccc(C(F)(F)F)c3)c2c1 CHEMBL216168 IC50 250.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)CCCc1ccccc1)c1ccccc1)C(C)C CHEMBL217684 IC50 250.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)CCc4ccccc4)ccc3CC[C@H]2O)cc1 CHEMBL466224 IC50 250.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(C(F)(F)F)cc2)cc1 CHEMBL571041 IC50 250.0 nM
Cc1ccc(S(=O)(=O)N/N=C/c2cn(CC(=O)Nc3ccc(F)cc3F)c3ccccc23)cc1 CHEMBL2440384 IC50 250.0 nM
Cc1ccccc1CN(CCCOc1ccc2c(c1)N(C)C(=O)C(C)(C)C(=O)N2C)CCc1cccnc1 CHEMBL3731891 IC50 250.0 nM
O=c1ccc2c(OCCCCOc3cccc(C(F)(F)F)c3)c3ccoc3cc2o1 CHEMBL3946873 EC50 250.0 nM
O=c1ccc2c(OCCCOc3ccc(Oc4ccccc4)cc3)c3ccoc3cc2o1 CHEMBL3946367 EC50 250.0 nM
Fc1ccc(-c2cccc3nc(-c4cncnc4)nc(NCc4ccccn4)c23)cc1 CHEMBL4450583 IC50 250.0 nM
COC(=O)CC(c1ccccc1)C(C(=O)N(C(C)C)C(C)C)c1ccccc1 CHEMBL216086 IC50 252.0 nM
Cc1cccc(CNC(=O)NCC(c2ccccc2)C(C(=O)N(C(C)C)C(C)C)c2cccnc2)c1 CHEMBL384780 IC50 252.0 nM
COc1ccc(CNC(=O)NCC(c2ccccc2)C(C(=O)N(C(C)C)C(C)C)c2cccnc2)cc1 CHEMBL384095 IC50 256.0 nM
OC(c1cccnc1)(c1cccnc1)C(c1ccccc1)N1CCOCC1 CHEMBL1090794 IC50 256.0 nM
CC1=C(c2ncnn2-c2cccc(F)n2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332442 IC50 256.0 nM
COc1ccc2c(-n3cnc(C)c3)nc(C#N)c(-c3cccc(F)c3)c2c1 CHEMBL215818 IC50 260.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL228329 IC50 260.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)Nc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL231300 IC50 260.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2c3cc(C(=O)N4CCC[C@H]4CNc4c(C)cccc4C)ccc3OC(C)(C)[C@@H]2O)cc1 CHEMBL389891 IC50 260.0 nM
CCCN(CC)[C@@H](c1ccccn1)[C@H](c1cccc(C#N)c1)N(CCOC)C[C@@H](C)CO CHEMBL4451245 IC50 260.0 nM
CC(C)(CNc1noc2cccc(O)c12)c1ccccc1 CHEMBL3298146 IC50 262.0 nM
COC(=O)C[C@@H](c1ccccc1)[C@H](C(=O)N(C(C)C)C(C)C)c1cccnc1 CHEMBL383874 IC50 265.0 nM
COC(=O)CC(c1cccnc1)C(C(=O)N(C(C)C)C(C)C)c1ccccc1 CHEMBL384974 IC50 266.0 nM
COc1cccc(CON2C(=O)CSC2c2ccc(C)c(C)c2)c1 CHEMBL385933 IC50 269.0 nM
CC(C)(CNC(=O)CC(F)(F)F)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1290737 IC50 270.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccccc4c3=O)Cc3ccco3)ccc21 CHEMBL3729281 IC50 270.0 nM
CCc1c(C)[nH]c2c1/C(=N/OC(=O)Nc1ccc(F)cc1)CCC2 CHEMBL217333 IC50 275.0 nM
OC(c1cccnc1-c1cccc(Cl)c1)C(c1cccnc1)c1ncco1 CHEMBL4094570 IC50 276.0 nM
CCc1c(C)[nH]c2c1/C(=N/NC(=O)Nc1ccc(SC)cc1)CCC2 CHEMBL216337 IC50 280.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(C)c4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL388538 IC50 280.0 nM
CCc1ccc(S(=O)(=O)N(Cc2c[nH]cn2)[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL230775 IC50 280.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)cc2Cl)n2nccc2N1 CHEMBL464067 IC50 280.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2CCCc3ccc(NC(=O)CCc4ccccc4)cc32)cc1 CHEMBL513656 IC50 280.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccncc3C)ccc21 CHEMBL3729196 IC50 280.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2cc(C)no2)[C@@H](c2nc3ccccc3s2)n2nc(C(F)(F)F)cc2N1 CHEMBL2042160 IC50 281.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)N[C@H](C)c1ccccc1)c1ccccc1)C(C)C CHEMBL216436 IC50 283.0 nM
CC1=C(c2ncnn2C2CCC2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(C)(C)C)cc2N1 CHEMBL2331998 IC50 283.0 nM
OC(c1cccnc1-c1cccc(Cl)c1)C(c1cccnc1)c1cccnc1 CHEMBL4089812 IC50 283.0 nM
OC(c1cccnc1)(c1cccnc1)C(c1ccccc1)N1CCCC1 CHEMBL1089159 IC50 284.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL231203 IC50 290.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)[C@H]4CCCN4Cc4cccc(OC(F)(F)F)c4)ccc3CC[C@H]2O)cc1 CHEMBL475630 IC50 290.0 nM
CC1=C(c2nc3ccc(F)cc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL566811 IC50 290.0 nM
CC(C)(CNC(=O)c1cscn1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1290621 IC50 290.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccccc3)ccc21 CHEMBL3729664 IC50 290.0 nM
O[C@@H](c1cccnc1-c1cccc(C(F)(F)F)c1)C(c1cccnc1)c1cccnc1 CHEMBL4076764 IC50 290.0 nM
COc1ccc(CCn2ncc(C(=O)c3ccc(C)c(C)c3)n2)cc1 CHEMBL212453 IC50 294.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCCc1ccccc1)c1ccccc1)C(C)C CHEMBL385960 IC50 298.0 nM
CC(C)C[C@H](NC(=O)c1ccccc1-c1ccccc1CNC(=O)OCc1ccccc1)C(N)=O CHEMBL146482 IC50 300.0 nM
C[C@H](CC(=O)NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)c1ccccc1 CHEMBL144174 IC50 300.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3C[C@@H]2O)cc1 CHEMBL398397 IC50 300.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)[C@H]4CCCN4Cc4cccc(OC)c4)ccc3CC[C@H]2O)cc1 CHEMBL494025 IC50 300.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2nc(C)c(C)s2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL606204 IC50 300.0 nM
c1ccc([C@@H]([C@H](c2ccccc2)N2CCCC2)N2CCCC2)cc1 CHEMBL2152524 IC50 300.0 nM
Cn1c(=O)c(OCCCN(CCc2cccnc2)Cc2ccncc2)cc2ccccc21 CHEMBL3893861 IC50 300.0 nM
CCCCN(CCCC)C(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL520917 IC50 310.0 nM
CC1=C(C(=O)N2CCCC2c2ccncc2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL601247 IC50 310.0 nM
CCCc1ncccc1CN(CCCOc1ccc2c(c1)N(C)C(=O)C(C)(C)C(=O)N2CC)CCn1ccc2oc(C)cc2c1=O CHEMBL3730685 IC50 310.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)Nc4ccc(Br)cc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL259118 IC50 316.0 nM
CCc1ccc(S(=O)(=O)N(CC(C)C)[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL396551 IC50 320.0 nM
CC(C)(CNC(=O)C1CC1(F)F)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289416 IC50 320.0 nM
CC(C)(CNC(=O)C1(C(F)(F)F)CCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289530 IC50 320.0 nM
CCn1c(=O)ccc2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21 CHEMBL3924627 IC50 320.0 nM
COC(=O)CC(c1cccnc1)C(C(=O)N(C(C)C)C(C)C)c1cccc(C#N)c1 CHEMBL386226 IC50 326.0 nM
COc1ccc(CCn2nnn[n+]2-c2cccc(C)c2C)cc1 CHEMBL387088 IC50 330.0 nM
COc1ccc(CCn2nnn[n+]2C2(c3ccc(C)cc3)CC2)cc1 CHEMBL387064 IC50 330.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL569184 IC50 330.0 nM
O=P(NCc1cccnc1-c1cccc(Cl)c1)(c1ccccc1)c1ccccc1 CHEMBL2312929 IC50 330.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4oc(C)cc4c3=O)Cc3cnccc3C)ccc21 CHEMBL3733333 IC50 330.0 nM
CN(C)c1ccc(-c2cccc3nc(-c4cncnc4)nc(NCc4ccccn4)c23)cc1 CHEMBL4078271 IC50 330.0 nM
Cc1cccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)c1 CHEMBL228491 IC50 340.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4ccc(Cl)cc4)ccc3CC[C@H]2O)cc1 CHEMBL467671 IC50 340.0 nM
COc1ccc(CCN2C(=O)N(NS(=O)(=O)Cc3ccccc3)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL569628 IC50 340.0 nM
CC(C)(CNC(=O)n1cccc1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1290618 IC50 340.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1cccc(F)c1)c1ccccc1)C(C)C CHEMBL385662 IC50 341.0 nM
CCc1c(C)[nH]c2c1/C(=N/OC(=O)Nc1ccc(SC)cc1)CCC2 CHEMBL217348 IC50 350.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)[C@H]4C[C@@H]4c4ccccc4)ccc3CC[C@H]2O)cc1 CHEMBL512242 IC50 350.0 nM
CC(C)(CNC(=O)c1cnccn1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289188 IC50 350.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1ccc(F)cc1)c1ccccc1)C(C)C CHEMBL385249 IC50 353.0 nM
CC(C)(CNC(=O)c1ccoc1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1290510 IC50 360.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccccc4c3=O)S(=O)(=O)c3ccccc3)ccc21 CHEMBL3731879 IC50 360.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1ccc(Br)cc1)c1ccccc1)C(C)C CHEMBL386975 IC50 362.0 nM
CCc1c2c(n(C)c1C)CCC/C2=N\OC(=O)Nc1ccc(C(C)=O)cc1 CHEMBL385237 IC50 368.0 nM
Cc1[nH]c2c(c1C)/C(=N/NC(=O)Nc1ccc(Cl)cc1)CCC2 CHEMBL217800 IC50 370.0 nM
CCc1c2c(n(C)c1CC)CCC/C2=N\N(C)C(=O)Nc1ccc(C(C)=O)cc1 CHEMBL216375 IC50 370.0 nM
CC(C)(CNC(=O)C1(C)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289417 IC50 370.0 nM
COc1cnccc1C(=O)NCC(C)(C)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289300 IC50 370.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)c4ccccc4)cnc3OC(C)(C)[C@H]2O)cc1 CHEMBL406415 IC50 378.0 nM
COc1cccc(CON2C(=O)CSC2c2ccc(Cl)cc2)c1 CHEMBL217014 IC50 380.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccsc4c3=O)Cc3ccncc3)ccc21 CHEMBL3732294 IC50 380.0 nM
CC1=C(c2ncnn2-c2ccc(C)cn2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332446 IC50 389.0 nM
COc1ccc(CCN2C(=O)CSC2(C)c2ccc(C)cc2)cc1 CHEMBL267425 IC50 390.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4occc4c3=O)Cc3cccnc3)ccc21 CHEMBL3730145 IC50 390.0 nM
CCCN(CC)[C@H](c1ccccn1)[C@@H](c1cccc(C#N)c1)N(CCOC)C[C@H](C)CO CHEMBL4527638 IC50 390.0 nM
C[C@H](OC(=O)NCc1ccccc1-c1cccnc1C(=O)NCC1CC1)c1ccccc1 CHEMBL148356 IC50 400.0 nM
COc1ccc(CCn2nnn[n+]2C2(c3ccc(C)cc3)CCCC2)cc1 CHEMBL217313 IC50 400.0 nM
Cc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL228441 IC50 400.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21 CHEMBL3731323 IC50 400.0 nM
CCCNC(=O)C1c2ccccc2C(=O)N1CC(C)c1ccc(Cl)cc1 CHEMBL3786344 IC50 400.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CC(=O)NCCc1ccccc1)c1ccccc1)C(C)C CHEMBL384706 IC50 410.0 nM
CC(C)(CNC(=O)c1ccco1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1290509 IC50 410.0 nM
CC1=C(c2ncnn2-c2cc(C)ccn2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2332445 IC50 410.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 CHEMBL2042149 IC50 419.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cc(C)cc(C)c2)n2nccc2N1 CHEMBL480990 IC50 420.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4sccc4c3=O)Cc3cccnc3)ccc21 CHEMBL3728819 IC50 420.0 nM
COc1cccc(C(=O)Nc2ccc3c(c2)[C@@H](NS(=O)(=O)c2ccc(C(C)C)cc2)[C@H](O)CC3)c1 CHEMBL512964 IC50 430.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)C#Cc4ccccc4)ccc3CC[C@H]2O)cc1 CHEMBL467479 IC50 430.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CC(=O)NCc1ccccc1F)c1ccccc1)C(C)C CHEMBL217251 IC50 432.0 nM
CCc1c(C)[nH]c2c1/C(=N/NC(=O)Nc1ccc(Cl)cc1)CCC2 CHEMBL216943 IC50 440.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3CC[C@H]2O)cc1 CHEMBL239807 IC50 440.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)cc2)n2nccc2N1 CHEMBL465939 IC50 440.0 nM
CCCCNC(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL481396 IC50 440.0 nM
CCN(CC)C(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL519762 IC50 440.0 nM
CC(C)(CNC(=O)C1CCCCO1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289850 IC50 440.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4occc4c3=O)Cc3cccnc3C)ccc21 CHEMBL3731925 IC50 440.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4oc(C)cc4c3=O)Cc3ccncc3)ccc21 CHEMBL3730746 IC50 440.0 nM
c1cncc(C(Cc2ccccc2-c2ccncc2)c2cccnc2)c1 CHEMBL4087512 IC50 444.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4ccccc4OC)ccc3CC[C@H]2O)cc1 CHEMBL467040 IC50 450.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4ccc(OC)cc4)ccc3CC[C@H]2O)cc1 CHEMBL467041 IC50 450.0 nM
CC(C)(CNC(=O)C1(O)CCCCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289639 IC50 450.0 nM
CC(C)(CNC(=O)c1ncccc1O)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289301 IC50 460.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4occc4c3=O)Cc3cnccc3C)ccc21 CHEMBL3730543 IC50 460.0 nM
O=C1CSC(c2ccc(Cl)c(Cl)c2)N1OCc1ccccc1 CHEMBL387104 IC50 463.0 nM
COc1cc([N+](=O)[O-])ccc1OCCCCOc1c2ccoc2cc2oc(=O)ccc12 CHEMBL3937251 EC50 476.0 nM
Cc1ccc(C2([n+]3nnnn3CCCc3ccccc3)CC2)cc1 CHEMBL217482 IC50 480.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)C[C@H]2c2ccc(OC)cc2)cc1 CHEMBL569185 IC50 480.0 nM
CC1=C(C(=O)N2CCC[C@H]2c2nnn(C)n2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL601035 IC50 480.0 nM
CC(C)(CNC(=O)C(C)(O)C(F)(F)F)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289419 IC50 480.0 nM
COc1ccc(CCN2C(=O)CSC23CCc2c(C)cccc23)cc1 CHEMBL385810 IC50 487.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)N[C@@H](C)c1ccccc1)c1ccccc1)C(C)C CHEMBL216254 IC50 490.0 nM
CCCNC(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL447625 IC50 490.0 nM
CC(C)(CNC(=O)C1CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289068 IC50 490.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)CCc1ccccc1Cl)c1ccccc1)C(C)C CHEMBL373704 IC50 498.0 nM
CC[C@H](NC(=O)c1cc(OC)ccc1NS(=O)(=O)c1ccc(C)cc1)c1ccccc1 CHEMBL318879 IC50 500.0 nM
Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)N(Cc2ccccc2)Cc2cc[nH]n2)cc1 CHEMBL319310 IC50 500.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4sccc4c3=O)Cc3cccnc3C)ccc21 CHEMBL3729707 IC50 500.0 nM
CC(C)(CN1C(=O)c2ccccc2C1C(=O)NCCCF)c1ccc(Cl)cc1 CHEMBL3785768 IC50 500.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(S(=O)(=O)NCCc4ccccc4)ccc3OC(C)(C)[C@H]2O)cc1 CHEMBL390128 IC50 510.0 nM
CC1=C(c2nc3ccccc3[nH]2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL569268 IC50 510.0 nM
COc1ccc2c(c1)c(/C=N/NS(=O)(=O)c1ccc(C)cc1)cn2CC(=O)Nc1ccc(Cl)cc1 CHEMBL2440387 IC50 510.0 nM
Cn1c(=O)ccc2cc(OCCCCCN(Cc3cccnc3)Cc3cccnc3)ccc21 CHEMBL3975620 IC50 510.0 nM
OC(c1cccnc1)(c1cccnc1)C(c1ccccc1)N1CCCOCC1 CHEMBL1091163 IC50 517.0 nM
COc1ccc([C@H]2CN(NS(C)(=O)=O)C(=O)N2CCc2ccc(OC(F)(F)F)cc2)cc1 CHEMBL583047 IC50 520.0 nM
Cn1ccnc1C(=O)NCC(C)(C)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289070 IC50 520.0 nM
O=P(c1ccccc1)(c1ccccc1)N(Cc1ccccn1)c1cccnc1 CHEMBL2313226 IC50 530.0 nM
COc1ccc(CC(=O)N2CCSC2c2ccc(C)c(C)c2)cc1 CHEMBL216496 IC50 537.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cccc(C)c2)n2nccc2N1 CHEMBL465125 IC50 540.0 nM
CC1=C(c2nc3cc(C(F)(F)F)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL585353 IC50 540.0 nM
CC(C)(CNC(=O)C1(C#N)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289299 IC50 540.0 nM
N#Cc1cccc(-c2ncccc2CNP(=O)(c2ccccc2)c2ccccc2)c1 CHEMBL2312930 IC50 540.0 nM
CN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21 CHEMBL3728509 IC50 540.0 nM
CCc1c(C)[nH]c2c1/C(=N/OC(=O)NCCc1ccccn1)CCC2 CHEMBL217672 IC50 547.0 nM
COc1ccc(CCn2nnn[n+]2-c2ccc(Cl)c(Cl)c2)cc1 CHEMBL217510 IC50 550.0 nM
COc1ccc(CCCN2C(=O)N(NS(C)(=O)=O)C[C@H]2c2ccc(OC)cc2)cc1 CHEMBL570360 IC50 560.0 nM
CC(C)(CNC(=O)C1(C#N)CCOCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289969 IC50 560.0 nM
CS(=O)(=O)Nc1cccc(-c2cc(F)ccc2CC(c2cccnc2)c2cccnc2)c1 CHEMBL4105373 IC50 579.0 nM
CCCCCN(CCCCC)C(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL517025 IC50 580.0 nM
CCN1C(=O)C(C)(C)C(=O)N(CC)c2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21 CHEMBL3732894 IC50 580.0 nM
CCCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21 CHEMBL3729766 IC50 580.0 nM
COCCN(C)C(c1ccccc1)C(O)(c1cccnc1)c1cccnc1 CHEMBL1092574 IC50 583.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CC(=O)NCCCc1ccccc1)c1ccccc1)C(C)C CHEMBL439539 IC50 589.0 nM
CCCCCNC(=O)C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 CHEMBL480611 IC50 590.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2CCCc3ccc(NC(=O)c4cccc(OC)c4)cc32)cc1 CHEMBL513486 IC50 590.0 nM
CCCN(c1ccon1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2312918 IC50 590.0 nM
CC[C@H](NC(=O)c1ccccc1NS(=O)(=O)c1ccc(OC)cc1)c1ccccc1 CHEMBL327816 IC50 600.0 nM
CC[C@H](NC(=O)c1ccccc1NS(=O)(=O)c1cccc2cccnc12)c1ccccc1 CHEMBL273418 IC50 600.0 nM
COc1ccc(CCN2C(=O)N(NS(=O)(=O)Cc3cccnc3)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL568957 IC50 600.0 nM
c1ccc([C@H]([C@@H](c2ccccc2)N2CCCC2)N2CCCC2)cc1 CHEMBL2152525 IC50 600.0 nM
CC(C)(CN1C(=O)c2ccccc2C1C(=O)NCCCC(F)F)c1ccc(F)cc1 CHEMBL3785198 IC50 600.0 nM
Cn1c(=O)ccc2cc(OCCCCCN(CCCc3ccccc3)c3cccnc3)ccc21 CHEMBL3904810 IC50 600.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)Cc4ccc(OC)cc4)cnc3OC(C)(C)[C@H]2O)cc1 CHEMBL259666 IC50 605.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)NCc4ccccc4)ccc3CC[C@H]2O)cc1 CHEMBL466858 IC50 610.0 nM
COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(C)c(C)c2)cc1 CHEMBL585163 IC50 610.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)Cc4c(F)cccc4Cl)cnc3OC(C)(C)[C@H]2O)cc1 CHEMBL258934 IC50 615.0 nM
COCCN(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2313227 IC50 620.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CCCN(CCn3ccc4oc(C)cc4c3=O)Cc3ccncc3)ccc21 CHEMBL3987081 IC50 620.0 nM
CC(C)(CNC(=O)C1(O)CCC(F)(F)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289743 IC50 630.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN(CCn3ccc4oc(C)cc4c3=O)Cc3cccnc3COC)ccc21 CHEMBL3967653 IC50 630.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cc(OC)cc(OC)c4)ccc3CC[C@H]2O)cc1 CHEMBL467672 IC50 640.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)c4cccc(Cl)c4)cnc3OC(C)(C)[C@H]2O)cc1 CHEMBL407161 IC50 649.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc3ccccc3c2)n2nccc2N1 CHEMBL467631 IC50 650.0 nM
CC1=C(C(=O)N2CCCC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL465276 IC50 660.0 nM
CC1=C(c2nc3ccc(Cl)cc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL567024 IC50 660.0 nM
CC1=C(C(=O)N2CCCC2c2ccccn2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL601456 IC50 660.0 nM
COc1ccc2c(NC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1 CHEMBL214876 IC50 680.0 nM
COc1ccc2c(=O)n(CCO)c(C#N)c(-c3cccc(F)c3)c2c1 CHEMBL214969 IC50 690.0 nM
CN(CCN(CCCOc1ccc2c(c1)N(C)C(=O)C(C)(C)C(=O)N2C)Cc1ccncc1)C(=O)c1ccccc1 CHEMBL3729169 IC50 690.0 nM
Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)N(Cc2ccccc2)Cc2nccn2C)cc1 CHEMBL95368 IC50 700.0 nM
CC[C@H](NC(=O)c1ccccc1NS(=O)(=O)c1ccc(C)cc1)c1ccccc1 CHEMBL94296 IC50 700.0 nM
Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)N(Cc2ccccc2)Cc2cccnc2)cc1 CHEMBL316302 IC50 700.0 nM
Cc1cccc(CNC(=O)OCc2ccccc2)c1-c1c(C)cccc1C(=O)NCCc1ccccn1 CHEMBL148210 IC50 700.0 nM
O=C(NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)OCc1ccccc1 CHEMBL148159 IC50 700.0 nM
COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 CHEMBL382154 EC50 700.0 nM
CCCCNC(=O)C1c2ccccc2C(=O)N1CC(C)c1ccc(Cl)cc1 CHEMBL3785486 IC50 700.0 nM
COC(=O)CC(c1cccnc1)C(C(=O)N(C(C)C)C(C)C)c1cccnc1 CHEMBL216310 IC50 708.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(NC(=O)c4cccc(Cl)c4)ccc3CC[C@H]2O)cc1 CHEMBL512460 IC50 710.0 nM
O=C(c1cccs1)N1CCN(CCOc2ccc(Cl)cc2)CC1 CHEMBL3262802 IC50 720.0 nM
CC1=C(c2ncn(-c3ccccc3C)n2)[C@@H](c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 CHEMBL2332461 IC50 722.0 nM
CC(C)(CNC(=O)C1(O)CCCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289531 IC50 730.0 nM
CC1=C(c2nc3ccccc3s2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL584937 IC50 740.0 nM
Cc1ccc(S(=O)(=O)N/N=C/c2cn(CC(=O)Nc3ccccc3Cl)c3ccccc23)cc1 CHEMBL2440383 IC50 740.0 nM
CCc1c(C)[nH]c2c1/C(=N/NC(=O)Nc1cccc(C3CCCN3)c1)CCC2 CHEMBL216954 IC50 750.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(C)c(C)c2)n2nccc2N1 CHEMBL480796 IC50 750.0 nM
CCCNC(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2312928 IC50 750.0 nM
O=c1ccc2c(OCCCCOc3ccc(Oc4ccccc4)cc3)c3ccoc3cc2o1 CHEMBL3901953 EC50 750.0 nM
O=c1ccc2c(OCCCCOCc3ccccc3)c3ccoc3cc2o1 CHEMBL3908386 EC50 750.0 nM
CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1ccccc1Cl)c1ccccc1)C(C)C CHEMBL386556 IC50 757.0 nM
CCc1ccc(S(=O)(=O)N[C@H]2c3cc(NC(=O)c4cccc(OC)c4)ccc3C[C@@H]2O)cc1 CHEMBL391455 IC50 760.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4occc4c3=O)Cc3ccc(C)nc3C)ccc21 CHEMBL3730396 IC50 760.0 nM
CCOc1ccc(CCN2C(=O)N(NS(C)(=O)=O)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL570805 IC50 770.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)c4cccc(C)c4)cnc3OC(C)(C)[C@H]2O)cc1 CHEMBL408935 IC50 776.0 nM
CC(C)(CNC(=O)CC1CCCCO1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289851 IC50 780.0 nM
CC(C)(CNc1noc2ccccc12)c1ccccc1 CHEMBL3298141 IC50 784.0 nM
COCCN(C)CCn1c(C#N)c(-c2cccc(F)c2)c2cc(OC)ccc2c1=O CHEMBL215050 IC50 790.0 nM
CC(C)(CNC(=O)C1(N)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289298 IC50 790.0 nM
CC(C)CCNC(=O)c1ccccc1-c1ccccc1CNC(=O)OCc1ccccc1 CHEMBL147381 IC50 800.0 nM
O=C1CC[C@@H](CN(Cc2ccc(F)cc2)S(=O)(=O)c2cccc(Cl)c2)N1 CHEMBL3127411 IC50 800.0 nM
COc1ccc2c(c1C)C(=O)N(Cc1ccccc1-c1ccccc1)C2C(=O)NC(C)(C)C CHEMBL3785621 IC50 800.0 nM
CC(C)(C)NC(=O)C1c2ccccc2C(=O)N1Cc1ccc(F)cc1-c1ccccc1 CHEMBL3785335 IC50 800.0 nM
Cc1ccc(S(=O)(=O)N/N=C/c2cn(CC(=O)Nc3ccccc3)c3ccccc23)cc1 CHEMBL2440398 IC50 810.0 nM
CN1C(=O)CC[C@H]1CN(Cc1ccc(F)cc1)S(=O)(=O)c1cccc(C#N)c1 CHEMBL3127398 IC50 810.0 nM
Cn1c(=O)ccc2cc(OCCCCCN(CCCc3ccccc3)Cc3cccnc3)ccc21 CHEMBL3937958 IC50 810.0 nM
COc1ccc(CCN2C(=O)CSC23CCc2cc(Cl)ccc23)cc1 CHEMBL383947 IC50 812.0 nM
CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cc(Cl)ccc2Cl)n2nccc2N1 CHEMBL464068 IC50 820.0 nM
CC(C)(CNC(=O)C1CCCO1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289744 IC50 830.0 nM
CN(C)C(c1ccccc1)C(O)(c1cccnc1)c1cccnc1 CHEMBL1090817 IC50 850.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN(CCc3cccnc3)C(=O)Cc3cn(C)c4ccccc34)ccc21 CHEMBL3985376 IC50 860.0 nM
COc1ccc2c(=O)n(CC(O)CO)c(C#N)c(-c3cccc(F)c3)c2c1 CHEMBL215023 IC50 870.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3c(cccc3NC(=O)c3cccc(OC)c3)C[C@H]2O)cc1 CHEMBL391488 IC50 880.0 nM
COc1c(C(C)=O)c(O)c(OCc2ccc(Br)cc2)c2occc12 CHEMBL426482 EC50 900.0 nM
COc1ccc(CCN2C(=O)N(NS(=O)(=O)CF)C[C@@H]2c2ccc(OC)cc2)cc1 CHEMBL571039 IC50 900.0 nM
CC(C)(CNC(=O)c1cocn1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1290739 IC50 900.0 nM
CC(C)(C)NC(=O)C1c2ccccc2C(=O)N1Cc1ccccc1-c1ccccc1 CHEMBL3786542 IC50 900.0 nM
CC(C)(C)NC(=O)C1c2ccccc2C(=O)N1Cc1cc(F)ccc1-c1ccc(F)cc1 CHEMBL3785765 IC50 900.0 nM
CCCCNC(=O)C1c2ccccc2C(=O)N1CC(C)c1ccc(F)cc1 CHEMBL3785933 IC50 900.0 nM
CCc1ccc(S(=O)(=O)N[C@@H]2c3cc(C(=O)N(CC)c4cc(F)ccc4F)cnc3OC(C)(C)[C@H]2O)cc1 CHEMBL258802 IC50 912.0 nM
COc1ccc(CON2C(=O)CSC2c2ccccc2)cc1 CHEMBL386837 IC50 924.0 nM
CCCN(c1cccc(S(C)(=O)=O)c1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2312921 IC50 930.0 nM
O=C1NCCc2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21 CHEMBL3957181 IC50 940.0 nM
CC(C)(CNC(=O)C1CCOCC1(C)C)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 CHEMBL1289968 IC50 960.0 nM
CC1=C(C(=O)N2CCC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL518717 IC50 970.0 nM
N#Cc1ccc(OCCN2CCN(CC(=O)Nc3nccs3)CC2)cc1 CHEMBL3262836 IC50 970.0 nM
CC1=C(c2nc3ccc(C)cc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 CHEMBL569493 IC50 980.0 nM
CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)S(=O)(=O)c3ccccc3)ccc21 CHEMBL3727860 IC50 980.0 nM
O=C1CSC(c2ccc(Cl)cc2)N1OCc1ccccc1 CHEMBL217096 IC50 997.0 nM
Cc1cccc(CNC(=O)OCc2ccccc2)c1-c1c(C)cccc1C(=O)NCCC(C)C CHEMBL147039 IC50 1000.0 nM
C[C@@H](CC(=O)NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)c1ccccc1 CHEMBL144107 IC50 1000.0 nM
CCCN(c1cncnc1)P(=O)(c1ccccc1)c1ccccc1 CHEMBL2313230 IC50 1000.0 nM
Cc1nnc(SCCCCOc2c3ccoc3cc3oc(=O)ccc23)s1 CHEMBL3932874 EC50 1000.0 nM