CC(C)Oc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)(F)F)c1 CHEMBL3182699 IC50 1.0 nM
CCOc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)c1 CHEMBL3183497 IC50 2.0 nM
CCOc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 CHEMBL3182449 IC50 2.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(Cl)c3)c2)c1 CHEMBL1086899 IC50 3.0 nM
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1 CHEMBL1081188 IC50 4.0 nM
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)(F)F)c1 CHEMBL3188749 IC50 4.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccs3)c2)c1 CHEMBL3182091 IC50 5.0 nM
COc1ccc(CC(=O)NCc2ccccc2-c2ccccc2C(=O)NCc2ccc(F)cc2F)cc1 CHEMBL148342 IC50 7.0 nM
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C(C)C)c1 CHEMBL3187764 IC50 7.0 nM
CCOc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1 CHEMBL3187482 IC50 9.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(C(F)(F)F)c3)c2)c1 CHEMBL3183773 IC50 10.0 nM
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)c1 CHEMBL3182359 IC50 10.0 nM
CC(C)c1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)(F)F)c1 CHEMBL3186000 IC50 11.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)c(Cl)c1 CHEMBL3916254 IC50 13.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C2CC2)C2CC2)n2c1COCC2)c1ccccc1 CHEMBL4108886 IC50 13.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCCC2)c1ccccc1 CHEMBL4113638 IC50 13.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3C(F)(F)F)c2)c1 CHEMBL3188857 IC50 14.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)c(Cl)c1 CHEMBL3967700 IC50 15.0 nM
CC(C)C(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3940405 IC50 19.0 nM
O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1 CHEMBL3186489 IC50 21.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)s1 CHEMBL3893027 IC50 21.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3Cl)c2)c1 CHEMBL3186695 IC50 23.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(F)c3)c2)c1 CHEMBL3182551 IC50 25.0 nM
CC[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL3977606 IC50 25.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3)c2)c1 CHEMBL1310568 IC50 27.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1SCC2)c1ccccc1 CHEMBL4115400 IC50 27.0 nM
O=C(Nc1cccc(NC(=O)c2cccs2)c1)c1ccccc1 CHEMBL3182777 IC50 29.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3OC(F)(F)F)c2)c1 CHEMBL3182725 IC50 29.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(C)c3)c2)c1 CHEMBL3185736 IC50 30.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(Cl)c(Cl)c1 CHEMBL3964723 IC50 30.0 nM
COc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(C)c3)c2)c1 CHEMBL3187806 IC50 31.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1CSC2)c1ccccc1 CHEMBL4115411 IC50 33.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCCC2CC2)n2c1COCC2)c1ccccc1 CHEMBL4110914 IC50 36.0 nM
O=C(Nc1cccc(NC(=O)c2ccco2)c1)c1ccccc1 CHEMBL1716797 IC50 37.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1SCC2)c1ccccc1 CHEMBL3970677 IC50 37.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccc(OC)n2)n2c1COCC2)c1ccccc1 CHEMBL4111274 IC50 40.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cc(F)ccc1Cl CHEMBL3923019 IC50 40.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cnc(OC)cn2)n2c1COCC2)c1ccccc1 CHEMBL4109024 IC50 41.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccccc1 CHEMBL4113378 IC50 42.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H](C)C2CC2)n2c1CCCC2)c1ccccc1 CHEMBL3970680 IC50 42.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1c(F)cccc1F CHEMBL3932941 IC50 44.0 nM
O=C(Nc1cccc(NC(=O)c2cccc(F)c2)c1)c1ccccc1 CHEMBL1532914 IC50 45.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CCOC2)c1ccccc1 CHEMBL4114021 IC50 46.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CCOC2C)c1ccccc1 CHEMBL4112626 IC50 46.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)C2CC2)CC3)c1 CHEMBL3936403 IC50 47.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1cnc(OC)cn1 CHEMBL4107349 IC50 48.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H]2CCc3ccccc32)n2c1COCC2)c1ccccc1 CHEMBL4109023 IC50 48.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H](c2ccccc2)C2CC2)n2c1CCCC2)c1ccccc1 CHEMBL4110154 IC50 48.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccc(F)cc1F CHEMBL4114039 IC50 49.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(F)(F)F)n2c1COCC2)c1ccccc1 CHEMBL4109525 IC50 49.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)cc1Cl CHEMBL3949141 IC50 49.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1c(F)cc(C(F)(F)F)cc1F CHEMBL3939057 IC50 50.0 nM
C[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccccc1 CHEMBL4115213 IC50 50.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2c1CCCC2)c1ccccc1 CHEMBL4114307 IC50 51.0 nM
O=C(Nc1cccc(NC(=O)c2cccc(Cl)c2)c1)c1ccccc1 CHEMBL3184966 IC50 52.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccc(C(F)(F)F)cn1 CHEMBL4110281 IC50 54.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1cnccn1 CHEMBL4107179 IC50 57.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H](C)c2ccc(F)cc2)n2c1CCCC2)c1ccccc1 CHEMBL3931470 IC50 58.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(OC)c(Cl)c1 CHEMBL3940749 IC50 61.0 nM
CCOC(=O)C[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2 CHEMBL4110052 IC50 62.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)C2CCC2)CC3)c1 CHEMBL3904473 IC50 64.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccccc1Cl CHEMBL3982446 IC50 64.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1Cl CHEMBL3980978 IC50 65.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ncccn2)c2n1CCOC2)c1ccc(C(F)(F)F)cc1 CHEMBL4109448 IC50 65.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@@H](c2ccc(F)cc2)C(C)C)c2n1CCOC2)c1ccccc1 CHEMBL3927565 IC50 67.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)cc1 CHEMBL3915314 IC50 68.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccccc1 CHEMBL3903744 IC50 69.0 nM
CCC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700371 IC50 70.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccccc1 CHEMBL3899390 IC50 70.0 nM
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C)c1 CHEMBL1480257 IC50 73.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(OC)c(Cl)c1 CHEMBL3982034 IC50 73.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccccc1 CHEMBL4108387 IC50 74.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)C2CC2)n2c1CCCC2)c1ccccc1 CHEMBL4108685 IC50 74.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(C)Cc2ccc(F)cc2)n2c1CCCC2)c1ccccc1 CHEMBL4108382 IC50 75.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cccc(C(F)(F)F)n1 CHEMBL3891601 IC50 76.0 nM
O=C(Nc1cccc(NC(=O)C2CCCCC2)c1)c1ccccc1 CHEMBL3184095 IC50 79.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC2CC2)n2c1COCC2)c1ccccc1Cl CHEMBL4109900 IC50 80.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2nccs2)c2n1CCCC2)c1ccccc1 CHEMBL4109673 IC50 80.0 nM
N#Cc1cccc(-c2nn([C@@H]3c4cc(F)cc(F)c4C[C@H]3O)c3c2CN(C(=O)C2CC2)CC3)c1 CHEMBL3700372 IC50 83.1 nM
O=C(Nc1cccc(NC(=O)c2ccccn2)c1)c1ccccc1 CHEMBL3182370 IC50 86.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CCS2)c1ccccc1 CHEMBL4112553 IC50 87.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccc(F)cc1Cl CHEMBL4110083 IC50 90.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)c2n1CCOC2)c1ccccc1Cl CHEMBL3893963 IC50 90.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3C)c2)c1 CHEMBL3181939 IC50 91.0 nM
CC(=O)N1C2CCC1c1c(-c3cccc(C#N)c3)nn(Cc3ccc(F)cc3F)c1C2 CHEMBL3940736 IC50 91.0 nM
C[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1CCCC2)c1ccc(Cl)cc1 CHEMBL3961619 IC50 92.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)c(F)c1 CHEMBL3909147 IC50 93.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(=O)OC)n2c1COCC2)c1ccccc1 CHEMBL4109984 IC50 93.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC2CCCCC2)n2c1CCCC2)c1ccccc1 CHEMBL4108975 IC50 93.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccncc3)c2)c1 CHEMBL3187891 IC50 95.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3902990 IC50 95.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CSC2)c1ccccc1 CHEMBL4109487 IC50 95.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCCc2ccc(F)cc2)n2c1CCCC2)c1ccccc1 CHEMBL4107838 IC50 97.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ncccc1Cl CHEMBL3945716 IC50 99.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)n3)nn2Cc2ccc(F)cc2)C1 CHEMBL3973950 IC50 99.5 nM
Cc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 CHEMBL3186207 IC50 100.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(OC)c(C(F)(F)F)c1 CHEMBL3926571 IC50 100.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC2CC2)n2c1COCC2)c1ccccc1 CHEMBL4106775 IC50 100.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1ccccc1 CHEMBL4113285 IC50 100.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(C)[C@@H](C)C(=O)OC(C)C)n2c1COCC2)c1ccccc1 CHEMBL3917080 IC50 100.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)c2n1CSC2)c1ccccc1 CHEMBL3958618 IC50 100.0 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO CHEMBL120526 IC50 100.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1C(C)OCC2)c1ccccc1 CHEMBL3984436 IC50 110.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccccc2)n2c1CCCC2)c1ccccc1 CHEMBL4113558 IC50 110.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2COC(C)=O)n2c1COCC2)c1ccccc1 CHEMBL4112767 IC50 110.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)cc1F CHEMBL3981304 IC50 110.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2ccc(C#N)cc2)C1 CHEMBL3909649 IC50 114.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)cc1 CHEMBL3945477 IC50 120.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ncccc2OC)n2c1COCC2)c1ccccc1 CHEMBL4107296 IC50 120.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(C)CC(=O)OC(C)C)n2c1COCC2)c1ccccc1 CHEMBL4109408 IC50 120.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2cnc(OC)cn2)n2c1COCC2)c1ccccc1 CHEMBL4115293 IC50 120.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2c2ccccc2)n2c1CCCC2)c1ccccc1 CHEMBL4107520 IC50 120.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC2CCCC2)n2c1CCCC2)c1ccccc1 CHEMBL4115227 IC50 120.0 nM
C[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccc(F)cc1 CHEMBL4111191 IC50 125.0 nM
O=C(Nc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1)c1ccccc1 CHEMBL3186206 IC50 130.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2(C)C)n2c1COCC2)c1ccccc1 CHEMBL4111217 IC50 130.0 nM
CCOC(=O)C[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL4106548 IC50 130.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1cnc(OC)cn1 CHEMBL4112315 IC50 130.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H](C)C(=O)OC(C)C)n2c1COCC2)c1ccccc1 CHEMBL3923026 IC50 130.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2COC)c2n1CCOC2)c1ccccc1 CHEMBL4114252 IC50 130.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2cnccn2)c2n1CCOC2)c1ccc(F)cc1Cl CHEMBL4113734 IC50 130.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC2CCCCC2)n2c1CCCC2)c1ccccc1 CHEMBL4109980 IC50 130.0 nM
CC(C)(C)C(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3929741 IC50 131.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccco3)c2)c1 CHEMBL3182773 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1c(F)cc(C#N)cc1F CHEMBL3977809 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1c(Cl)cncc1Cl CHEMBL3943433 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1C CHEMBL3952149 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(Cl)c(Cl)c1 CHEMBL3902082 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ccon2)n2c1COCC2)c1ccccc1 CHEMBL4108251 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ncccn2)c2n1CCOC2)c1ccccc1 CHEMBL4113338 IC50 140.0 nM
COC(=O)[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@@H](c2ccc(F)cc2)C(C)C)n2c1COCC2 CHEMBL4108993 IC50 140.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(=O)OC(C)C)n2c1COCC2)c1ccccc1 CHEMBL4115401 IC50 140.0 nM
CCc1ccccc1NC(=O)c1cccc(NC(=O)c2ccccc2)c1 CHEMBL5201126 IC50 148.0 nM
COc1ccc(OC)c(C(=O)Nc2cccc(NC(=O)c3cccc(C)c3)c2)c1 CHEMBL3317851 IC50 150.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccc(Cl)cc3)c2)c1 CHEMBL3186471 IC50 150.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccc(N(C)C)cc3)c2)c1 CHEMBL3188463 IC50 150.0 nM
CCC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL3912795 IC50 150.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC3CC3C2)n2c1COCC2)c1ccccc1 CHEMBL4108409 IC50 150.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2nccs2)c2n1CCOC2)c1ccccc1 CHEMBL4108043 IC50 150.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1CSCC2)c1ccccc1 CHEMBL4109779 IC50 150.0 nM
C[C@H]1CCCN1C(=O)c1cc(C(=O)NCc2c(F)cccc2Cl)c2n1CCOC2 CHEMBL3942026 IC50 150.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cccs1 CHEMBL3983800 IC50 150.0 nM
O=C(Nc1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1)c1ccccc1 CHEMBL3186946 IC50 160.0 nM
O=C(Nc1cccc(NC(=O)c2ccsc2)c1)c1ccccc1 CHEMBL3183945 IC50 160.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)c(C(F)(F)F)c1 CHEMBL3914497 IC50 160.0 nM
C[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(F)(F)F)c2n1CCOC2)c1ccc(F)cc1 CHEMBL4107973 IC50 160.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@H](F)C2)n2c1COCC2)c1ccccc1 CHEMBL3983823 IC50 160.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2c1COCC2)c1ccccc1 CHEMBL4107748 IC50 160.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(C)CCOC)n2c1CCCC2)c1ccccc1 CHEMBL4112777 IC50 160.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2cnccn2)n2c1COCC2)c1ccccc1 CHEMBL4110888 IC50 170.0 nM
CCC(NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1nccs1 CHEMBL4106825 IC50 170.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2nccs2)n2c1COCC2)c1ccccc1 CHEMBL4115436 IC50 170.0 nM
CCOC(=O)[C@H](C)N(C)C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL3961794 IC50 170.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cnccn2)n2c1COCC2)c1ccc(F)cc1Cl CHEMBL4108948 IC50 170.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ncccn2)n2c1COCC2)c1ccc(F)cc1Cl CHEMBL4110401 IC50 170.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CCOC2)c1ncccn1 CHEMBL4111972 IC50 170.0 nM
CC(=O)N1CCc2c(c(-c3cccc(OC(F)(F)F)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700347 IC50 171.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2ccc(Cl)nc2)C1 CHEMBL3935052 IC50 172.0 nM
COc1cc(C(=O)Nc2cccc(NC(=O)c3cccc(C)c3)c2)ccn1 CHEMBL3317854 IC50 180.0 nM
CCNC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(Cl)cc(Cl)c3C[C@H]2O)C1 CHEMBL3703717 IC50 180.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2COC(F)(F)F)n2c1COCC2)c1ccccc1 CHEMBL4111270 IC50 180.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2C(C)(C)C)n2c1COCC2)c1ccccc1 CHEMBL4111693 IC50 180.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2ccc(F)cn2)n2c1COCC2)c1ccccc1 CHEMBL4112839 IC50 180.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL4112954 IC50 180.0 nM
CCOC(=O)CNC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL4115511 IC50 180.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2nnn(C)n2)n2c1COCC2)c1ccccc1 CHEMBL4113675 IC50 180.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C(C)c2ccc(F)cc2)C1 CHEMBL3902433 IC50 187.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccc(C(C)(C)C)cc3)c2)c1 CHEMBL3181946 IC50 190.0 nM
CC(=O)N1CCc2c(c(-c3cccc(Cl)c3)nn2[C@H]2c3cc(F)cc(F)c3C[C@@H]2O)C1 CHEMBL3700348 IC50 190.0 nM
CC(=O)N1CCc2c(c(-c3cc(C(F)(F)F)ccn3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3922650 IC50 190.0 nM
C[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1cccc(F)c1 CHEMBL4108755 IC50 190.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccccc2)n2c1COCC2)c1cnc(OC)cn1 CHEMBL4115365 IC50 190.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)C(C)(C)C)n2c1COCC2)c1ccccc1 CHEMBL4109598 IC50 190.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccc(F)cc2)n2c1C(C)OCC2)c1ccccc1 CHEMBL4113413 IC50 190.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(Cl)cc1 CHEMBL3907873 IC50 190.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2cnccn2)c2n1CCOC2)c1ccc(F)cc1F CHEMBL4112096 IC50 190.0 nM
C[C@H]1CCCN1C(=O)c1cc(C(=O)NCc2ccc(F)cc2Cl)c2n1CCOC2 CHEMBL3895872 IC50 190.0 nM
CC[C@@H](NCc1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc2c(c1)OC(F)(F)O2 CHEMBL3966685 IC50 200.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2Cc3ccccc3C2)n2c1COCC2)c1ccccc1 CHEMBL4115618 IC50 200.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccc(OC)nc2)n2c1COCC2)c1ccccc1 CHEMBL4110602 IC50 200.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)c2n1CCOC2)c1ccccc1 CHEMBL3898615 IC50 200.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)c2n1CCOC2)c1ccc(F)cc1 CHEMBL3909518 IC50 200.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1CCCC2)c1ccc(C#N)cc1 CHEMBL3922942 IC50 200.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCCCC2)n2c1CCCC2)c1ccccc1 CHEMBL4115258 IC50 200.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CCOC2)c1ncccn1 CHEMBL4114830 IC50 200.0 nM
O=C(NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)OCc1ccccc1 CHEMBL148159 IC50 200.0 nM
CCCS(=O)(=O)Nc1ccccc1C(=O)N[C@H](CC)c1ccc(OC)nc1 CHEMBL5195455 IC50 200.0 nM
COc1ccc(F)c(-c2nn([C@@H]3c4cc(F)cc(F)c4C[C@H]3O)c3c2CN(C(C)=O)CC3)c1 CHEMBL3700349 IC50 204.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3OC(C)C)c2)c1 CHEMBL3317852 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccnc(C(F)(F)F)c1F CHEMBL3905599 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)cc1F CHEMBL3944449 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccccc1Cl CHEMBL4110961 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C#N)n2c1COCC2)c1ccccc1 CHEMBL4111050 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2cnoc2)c2n1CCOC2)c1ccccc1 CHEMBL4114197 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(C)C)c2n1CCOC2)c1ccccc1 CHEMBL4106626 IC50 210.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2c(C)noc2C)n2c1CCCC2)c1ccccc1 CHEMBL4108471 IC50 210.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2cnccc2Cl)C1 CHEMBL3896438 IC50 215.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)n3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3891096 IC50 216.0 nM
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 CHEMBL3188343 IC50 220.0 nM
C[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccccc2F)c2n1CCOC2)c1ccc(F)cc1 CHEMBL4109876 IC50 220.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccc(OC)nc1 CHEMBL4108008 IC50 220.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ncccn1 CHEMBL4109619 IC50 220.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)c2n1CCOC2)c1ccccc1 CHEMBL4112205 IC50 220.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2cc(C(F)(F)F)ccc2Cl)c2n1CCOC2)c1ccccc1 CHEMBL4107144 IC50 220.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2c1COCC2)c1ncccn1 CHEMBL4108969 IC50 220.0 nM
CCCCS(=O)(=O)Nc1ccccc1C(=O)NC(CC)c1ccc(OC)nc1 CHEMBL4592278 IC50 220.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(Br)c3C[C@H]2O)C1 CHEMBL3700350 IC50 226.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2CC(=O)OC(C)C)n2c1COCC2)c1ccccc1 CHEMBL4108480 IC50 230.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)COC)n2c1COCC2)c1ccccc1 CHEMBL4109035 IC50 230.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(Cl)s1 CHEMBL3955158 IC50 230.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(C)c3C[C@H]2O)C1 CHEMBL3700379 IC50 231.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)n3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700351 IC50 239.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C#N)c(Cl)c1 CHEMBL3958545 IC50 240.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2c2ccc(OC)nc2)n2c1COCC2)c1ccccc1 CHEMBL4115509 IC50 240.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@H](Oc3ccc(F)cc3)C2)n2c1COCC2)c1ccccc1 CHEMBL3925619 IC50 240.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ncccn1 CHEMBL4108024 IC50 240.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccnc2OC)n2c1COCC2)c1ccccc1 CHEMBL4115397 IC50 240.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccc(O)n2)n2c1COCC2)c1ccccc1 CHEMBL4111458 IC50 240.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)c2ccccn2)CC3)c1 CHEMBL3982643 IC50 246.0 nM
O=C(Nc1cccc(NC(=O)c2ccncc2)c1)c1ccccc1 CHEMBL3188245 IC50 250.0 nM
CC(C)C(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700373 IC50 250.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccc(C(F)(F)F)cc1 CHEMBL4107340 IC50 250.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(CC)CC)n2c1COCC2)c1ccccc1 CHEMBL4115465 IC50 250.0 nM
[C-]#[N+]c1cccc(CNC(=O)c2cc(C(=O)N[C@H](CC)c3ccccc3)c3n2CCOC3)c1 CHEMBL4111367 IC50 250.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2c1COCC2)c1ccc(OC)nc1 CHEMBL4113971 IC50 250.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccccc1C(F)(F)F CHEMBL3956964 IC50 250.0 nM
CCC(c1ccc(Cl)cc1)n1nc(-c2ccc(F)cc2)c2c1CCN(C(C)=O)C2 CHEMBL3890305 IC50 251.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2C(c2ccc(F)cc2)C2CC2)C1 CHEMBL3930416 IC50 258.0 nM
CN(C)c1ccc(C(=O)Nc2cccc(NC(=O)c3ccccc3)c2)cc1 CHEMBL3184653 IC50 260.0 nM
COC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700376 IC50 260.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@H]2C)n2c1COCC2)c1ccccc1 CHEMBL4110063 IC50 260.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC2CC2)n2c1CCCC2)c1ccccc1 CHEMBL4110955 IC50 260.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)c(C(F)(F)F)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700352 IC50 270.0 nM
CC(=O)N1CCc2c(c(-c3ccc(Cl)s3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3961843 IC50 270.0 nM
CCOC(=O)CN(C)C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL4109494 IC50 270.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@H]2C)c2n1CCOC2)c1ccccc1 CHEMBL4110802 IC50 270.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1CSCC2)c1ccccc1 CHEMBL3904671 IC50 270.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)c2n1CCOC2)c1ccc(F)cc1 CHEMBL4106952 IC50 270.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@H](OC)C2)n2c1COCC2)c1ccc(F)cc1Cl CHEMBL3918516 IC50 270.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cccc(OC)n1 CHEMBL3938715 IC50 270.0 nM
CC1(C(=O)N2CCc3c(c(-c4cccc(C#N)c4)nn3Cc3ccc(F)cc3F)C2)COC1 CHEMBL3930952 IC50 276.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(OC(F)(F)F)cc1 CHEMBL3946531 IC50 280.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(Br)s1 CHEMBL3969413 IC50 280.0 nM
CCC(NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ncc(C(F)(F)F)s1 CHEMBL3911022 IC50 280.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ncccn2)c2n1CCOC2)c1ccc(F)cc1Cl CHEMBL4113363 IC50 280.0 nM
CC(=O)N1CCc2c(c(-c3cccc(OC(F)(F)F)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3902326 IC50 285.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(Cl)c(C(F)(F)F)c1 CHEMBL3982747 IC50 290.0 nM
O=C(N[C@H](c1ccc(F)cc1)C1CC1)c1cc(C(=O)N2CCCC2)n2c1COCC2 CHEMBL3947683 IC50 290.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2c2ccccn2)n2c1COCC2)c1ccccc1 CHEMBL4110186 IC50 290.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL4108113 IC50 290.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)c2n1CCOC2)c1ccccc1C(F)(F)F CHEMBL3912008 IC50 290.0 nM
CCCC(=O)C1CCN(c2ncnc3c2CN(C(=O)c2ccc(-c4ccccc4)cc2)CC3)CC1 CHEMBL2324344 IC50 300.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)cc1Cl CHEMBL3899413 IC50 300.0 nM
O=C(N[C@@H](c1ccc(F)cc1)C1CC1)c1cc(C(=O)N2CCCC2)n2c1COCC2 CHEMBL4111851 IC50 300.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ncc(C(F)(F)F)cn1 CHEMBL4106760 IC50 300.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ncccn2)c2n1CCOC2)c1ccccc1 CHEMBL4112061 IC50 300.0 nM
O=C(Nc1cccc(NC(=O)c2ccc(F)cc2)c1)c1ccccc1 CHEMBL3184075 IC50 310.0 nM
CCC(NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccccc1OC(F)F CHEMBL3941070 IC50 310.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccn2)n2c1COCC2)c1ccccc1 CHEMBL4106750 IC50 310.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cnccn2)n2c1COCC2)c1ccccc1 CHEMBL4111602 IC50 310.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cnccn2)c2n1CCOC2)c1ccc(F)cc1Cl CHEMBL4111495 IC50 310.0 nM
CC(NC(=O)c1cc(C(=O)N[C@@H](c2ccc(F)cc2)C(C)C)n2c1COCC2)c1ccno1 CHEMBL4114876 IC50 310.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC2CCOCC2)n2c1CCCC2)c1ccccc1 CHEMBL4109405 IC50 310.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ncccn2)n2c1COCC2)c1ccccc1Cl CHEMBL4109910 IC50 310.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2c2c(C)noc2C)n2c1COCC2)c1ccccc1 CHEMBL4111634 IC50 320.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccccc2C#N)n2c1COCC2)c1ccccc1 CHEMBL4108728 IC50 320.0 nM
CCOC(=O)[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1ccccc1 CHEMBL4108830 IC50 320.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)n2c1SCC2)c1ccccc1 CHEMBL4114993 IC50 320.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(OC)cc2)n2c1CCCC2)c1ccccc1 CHEMBL4107886 IC50 320.0 nM
COc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3)c2)c1 CHEMBL3183938 IC50 330.0 nM
Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3C(C)C)c2)c1 CHEMBL3184438 IC50 330.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@H](OCC3CC3)C2)n2c1COCC2)c1ccccc1 CHEMBL3953806 IC50 330.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cccc(C(=O)OC)c2)n2c1COCC2)c1ccccc1 CHEMBL4110894 IC50 330.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)F)cc1 CHEMBL3955229 IC50 340.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cc(F)c(C#N)c(F)c1 CHEMBL3891834 IC50 340.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC(C)C)n2c1COCC2)c1ccccc1 CHEMBL4108134 IC50 340.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2nc(C)c(C)s2)c2n1CCCC2)c1ccccc1 CHEMBL4110734 IC50 340.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(Cl)cc(Cl)c3C[C@H]2O)C1 CHEMBL3700353 IC50 350.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(SC(F)(F)F)cc1 CHEMBL3918686 IC50 350.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ncc(C(F)(F)F)cn1 CHEMBL4106894 IC50 350.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ncco2)n2c1COCC2)c1ccccc1 CHEMBL4114329 IC50 350.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(C(=O)OC)cc2)n2c1COCC2)c1ccccc1 CHEMBL4113468 IC50 350.0 nM
COc1ccc(-n2nc(Sc3ccc(C)cc3)c(C)c(C#N)c2=O)cc1 CHEMBL4468526 IC50 350.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2Cc2c(F)cccc2F)C1 CHEMBL3918898 IC50 359.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cnccn2)n2c1COCC2)c1ccccc1 CHEMBL4112095 IC50 360.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccc(O)c2)n2c1COCC2)c1ccccc1 CHEMBL4112373 IC50 360.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N[C@@H](C)c2ncccn2)c2n1CCOC2)c1ccc(F)cc1 CHEMBL3972656 IC50 360.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2[C@H]2c3cc(F)cc(F)c3C[C@@H]2O)C1 CHEMBL3700354 IC50 370.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COC(C)(C)C2)c1ccc(C#N)cc1 CHEMBL3975511 IC50 370.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)c(C(F)(F)F)c3)nn2[C@H]2c3cc(F)cc(F)c3C[C@]2(C)O)C1 CHEMBL3700355 IC50 375.0 nM
CNC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3909656 IC50 380.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2C(C)C)n2c1COCC2)c1ccccc1 CHEMBL4113167 IC50 380.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2COC)n2c1COCC2)c1ccccc1 CHEMBL4109481 IC50 380.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccno2)n2c1COCC2)c1ccccc1 CHEMBL4110482 IC50 380.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)cc1 CHEMBL3947216 IC50 380.0 nM
O=C(Nc1cccc(C(=O)Nc2nccs2)c1)c1ccccc1 CHEMBL5181189 IC50 388.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@H]2C(C)C)c2n1CCOC2)c1ccccc1 CHEMBL4112131 IC50 390.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(Cl)c3C[C@H]2O)C1 CHEMBL3703716 IC50 393.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2Cc2ccc(Cl)c(F)c2)C1 CHEMBL3927377 IC50 398.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(OC)cc1 CHEMBL3904181 IC50 400.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(F)(F)F)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL4114380 IC50 410.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)c2ccncc2F)CC3)c1 CHEMBL3958523 IC50 416.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2C(C)n2cccn2)n2c1COCC2)c1ccccc1 CHEMBL4108310 IC50 420.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)NCc2cnccn2)c2n1CCOC2)c1ccc(F)cc1 CHEMBL4109859 IC50 420.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2ncccc2C)C1 CHEMBL3891734 IC50 422.0 nM
CC(=O)N1CCc2c(c(-c3cc(C#N)ccn3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3921502 IC50 422.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccccc2S(C)(=O)=O)n2c1COCC2)c1ccccc1 CHEMBL4112135 IC50 430.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(Cl)cc(F)c3C[C@H]2O)C1 CHEMBL3700356 IC50 439.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(Cl)nc1 CHEMBL3909753 IC50 440.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccccc1C(F)(F)F CHEMBL4107754 IC50 440.0 nM
COc1cccc(-c2nn([C@@H]3c4cc(F)cc(F)c4C[C@H]3O)c3c2CN(C(C)=O)CC3)c1 CHEMBL3700357 IC50 442.0 nM
CO[C@@H]1Cc2c(F)cc(F)cc2[C@H]1n1nc(-c2cccc(Cl)c2)c2c1CCN(C(C)=O)C2 CHEMBL3700374 IC50 446.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2C2CC2)n2c1COCC2)c1ccccc1 CHEMBL4108009 IC50 450.0 nM
CC(NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1CCCC2)c1ncccn1 CHEMBL4111592 IC50 450.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C#N)s1 CHEMBL3913042 IC50 450.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(CC)Cc2nnn(C)n2)n2c1COCC2)c1ccccc1 CHEMBL4115362 IC50 450.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL3941186 IC50 460.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cncc(F)c2)n2c1COCC2)c1ccccc1 CHEMBL4109390 IC50 460.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)n3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3924873 IC50 462.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(OC(F)F)cc1 CHEMBL3931116 IC50 470.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL3966365 IC50 470.0 nM
CC[C@H](NC(=O)c1cc(C(=O)NCC2CC2)c2n1CCOC2)c1ccccc1 CHEMBL3930635 IC50 470.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)c2n1CCSC2)c1ccccc1 CHEMBL3917200 IC50 470.0 nM
CC[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@H](CC)c2ccc(C(F)(F)F)nc2)c2n1CCOC2 CHEMBL3963599 IC50 470.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ncccn2)c2n1CCOC2)c1ccc(F)cc1 CHEMBL4112236 IC50 470.0 nM
CC[C@@H](NC(=O)c1c(Cl)c(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccccc1 CHEMBL3950718 IC50 470.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@H]2CCc3ccccc32)C1 CHEMBL3700370 IC50 479.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(C(F)(F)F)cc1C(F)(F)F CHEMBL3938036 IC50 480.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2c2cc(C)no2)n2c1COCC2)c1ccccc1 CHEMBL4106797 IC50 480.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2cnccn2)n2c1COCC2)c1ccccc1Cl CHEMBL4108079 IC50 480.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCCc2ccccn2)n2c1COCC2)c1ccccc1 CHEMBL4107275 IC50 490.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(F)c(C#N)c1 CHEMBL3944518 IC50 490.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(C)CC2CC2)n2c1COCC2)c1ccccc1 CHEMBL4106667 IC50 490.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3703718 IC50 495.0 nM
O=C(Nc1cccc(NC(=O)c2ccccc2Cl)c1)c1ccccc1 CHEMBL3182809 IC50 500.0 nM
O[C@@H]1Cc2c(F)cc(F)cc2[C@H]1n1nc(-c2ccc(F)cc2)c2c1CCN(CC1CC1)C2 CHEMBL3700377 IC50 500.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(C4CC4)c3C[C@H]2O)C1 CHEMBL3700380 IC50 500.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2C(C)c2ccc(F)cc2)C1 CHEMBL3916860 IC50 500.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C(C)OC)n2c1COCC2)c1ccccc1 CHEMBL4113206 IC50 500.0 nM
CC(=O)N1Cc2c(-c3ccc(F)cc3)nn(Cc3ccc(F)cc3F)c2CC1C CHEMBL3892791 IC50 511.0 nM
CC(c1ccc(F)cc1)n1nc(-c2ccc(F)cc2)c2c1CCN(C(=O)N1CCOCC1)C2 CHEMBL3946442 IC50 511.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)n3)nn2[C@@H]2c3cc(Cl)cc(Cl)c3C[C@H]2O)C1 CHEMBL3703719 IC50 518.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccc(OC)n2)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL4113690 IC50 520.0 nM
CCC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3945883 IC50 530.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ncccn2)n2c1COCC2)c1ccccc1 CHEMBL4112709 IC50 530.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccc(C(F)(F)F)nc2)n2c1COCC2)c1ccccc1 CHEMBL4114543 IC50 530.0 nM
CC(c1ccc(F)cc1)n1nc(-c2ccc(F)cc2)c2c1CCN(S(C)(=O)=O)C2 CHEMBL3937584 IC50 540.0 nM
CCOC(=O)[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL4108803 IC50 540.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2nc3ccccc3o2)c2n1CCOC2)c1ccccc1 CHEMBL4108454 IC50 540.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cccc(C#N)c1 CHEMBL3958238 IC50 550.0 nM
CCC(NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(C)(F)F)cc1 CHEMBL3891701 IC50 550.0 nM
CC(NC(=O)c1cc(C(=O)N[C@@H](c2ccc(F)cc2)C(C)C)n2c1COCC2)c1cnccn1 CHEMBL4111504 IC50 550.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@H](F)C2)n2c1CCCC2)c1ccccc1 CHEMBL3895095 IC50 550.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC(c3ccccc3)C2)n2c1CCCC2)c1ccccc1 CHEMBL4112964 IC50 550.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@H](OC)C2)n2c1COCC2)c1ccccc1 CHEMBL3972797 IC50 560.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ncccn2)n2c1COCC2)c1ccccc1 CHEMBL4109784 IC50 560.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1ccc(OC)nc1 CHEMBL4113316 IC50 560.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@@H]2c3cc(Cl)cc(F)c3C[C@H]2O)C1 CHEMBL3703720 IC50 568.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H]2CCc3ccccc32)n2c1COCC2)c1ccccc1 CHEMBL4106522 IC50 570.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)C2CCOCC2)CC3)c1 CHEMBL3931512 IC50 585.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCCC2)n2c1CCCC2)c1ccccc1 CHEMBL4113705 IC50 590.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3944503 IC50 598.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1ccc(C#N)cc1 CHEMBL4115632 IC50 600.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCN(C)CC2c2ccccc2)n2c1COCC2)c1ccccc1 CHEMBL4106579 IC50 600.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2c(C)noc2C)n2c1COCC2)c1ccccc1 CHEMBL4114054 IC50 600.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1CCCC2)c1ccc(C(F)(F)F)nc1 CHEMBL3963892 IC50 600.0 nM
COc1ccc(CC(=O)NCc2ccccc2-c2ccccc2C(=O)NCCc2cccnc2)cc1 CHEMBL1671897 IC50 600.0 nM
CCC(NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1cnc(OC)nc1 CHEMBL4110129 IC50 620.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2c(C)noc2C)c2n1CCOC2)c1ccccc1 CHEMBL4113836 IC50 620.0 nM
CC[C@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2ncccn2)c2n1CCOC2)c1ccccc1 CHEMBL3947525 IC50 620.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cnco2)c2n1CCCC2)c1ccccc1 CHEMBL4110519 IC50 620.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ncn[nH]2)n2c1COCC2)c1ccccc1 CHEMBL4108879 IC50 650.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccccn1 CHEMBL3932322 IC50 650.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2c(C)noc2C)n2c1COCC2)c1ccccc1 CHEMBL4112817 IC50 650.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2Cc2ccc(C(F)(F)F)cc2)C1 CHEMBL3944769 IC50 659.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccnc2C(F)(F)F)n2c1COCC2)c1ccccc1 CHEMBL4113829 IC50 660.0 nM
CCC(NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1nccs1 CHEMBL3985368 IC50 670.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCN(c3ccccn3)C[C@@H]2C)n2c1COCC2)c1ccccc1 CHEMBL3937289 IC50 670.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(F)cc2F)c2n1CCOC2)c1cccc(OC)n1 CHEMBL4107809 IC50 670.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@H]2c3cc(F)cc(F)c3C[C@@H]2O)C1 CHEMBL3703721 IC50 675.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(Cl)ccc3C[C@H]2O)C1 CHEMBL3700358 IC50 685.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)C)n2c1COCC2)c1ccccc1 CHEMBL4110609 IC50 690.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cncc(C(F)(F)F)c2)n2c1COCC2)c1ccccc1 CHEMBL4112333 IC50 690.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](c2ccc(F)cc2)C2CC2)n2c1COCC2)c1ccccc1 CHEMBL4111128 IC50 710.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@@H]2CCc3ccccc32)C1 CHEMBL3700369 IC50 712.0 nM
COc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(C)=O)CC3)c1 CHEMBL3933470 IC50 720.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)C2CCCC2)CC3)c1 CHEMBL3975317 IC50 722.0 nM
CC[C@@H]1CCCN1C(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2 CHEMBL4106836 IC50 730.0 nM
CCC(NC(=O)c1cc(C(=O)N[C@H](CC)c2ccccc2)c2n1CCOC2)c1ccc(C)nc1 CHEMBL4112156 IC50 730.0 nM
CC(c1ccc(F)cc1)n1nc(-c2ccc(F)cc2)c2c1CCN(C(=O)N1CC[C@H](O)C1)C2 CHEMBL3922102 IC50 734.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2nnn(CC)n2)n2c1COCC2)c1ccccc1 CHEMBL4111421 IC50 750.0 nM
C[C@H](O)C(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 CHEMBL3945244 IC50 756.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700359 IC50 773.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N(C)Cc2ccccn2)n2c1COCC2)c1ccccc1 CHEMBL4114068 IC50 780.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](CC)c2cccc(S(C)(=O)=O)c2)n2c1COCC2)c1ccccc1 CHEMBL4111023 IC50 780.0 nM
CC(=O)N1CCc2c(c(-c3cccc(OC(F)(F)F)c3)nn2[C@H]2c3cc(F)cc(F)c3C[C@@H]2O)C1 CHEMBL3700360 IC50 789.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C#N)cc1Cl CHEMBL3907236 IC50 790.0 nM
O=C(Nc1cccc(NC(=O)c2ccoc2)c1)c1ccccc1 CHEMBL3188024 IC50 800.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(C(F)(F)F)cc1C(F)(F)F CHEMBL3967638 IC50 800.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@@H]2c3cc(Cl)ccc3C[C@H]2O)C1 CHEMBL3700361 IC50 804.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)cn1 CHEMBL3980984 IC50 820.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@@H](C)c2ccc(F)cc2)n2c1COCC2)c1ncccn1 CHEMBL3898164 IC50 820.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2[C@@H](COC)CC[C@@H]2COC)n2c1COCC2)c1ccccc1 CHEMBL4108362 IC50 820.0 nM
CC[C@@H](NC(=O)c1c(Br)c(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL3942000 IC50 820.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(C(F)(F)F)c(F)c1 CHEMBL3916516 IC50 830.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CC[C@@H](OC)C2)n2c1CCCC2)c1ccccc1 CHEMBL4112807 IC50 840.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COC(C)(C)C2)c1ccc(C(F)(F)F)nc1 CHEMBL3924111 IC50 850.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)c2ccncn2)CC3)c1 CHEMBL3889480 IC50 864.0 nM
CC[C@@H](NC(=O)c1c(Cl)c(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 CHEMBL3919500 IC50 870.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(C(F)(F)F)cc1Cl CHEMBL3923515 IC50 880.0 nM
CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1 CHEMBL3700362 IC50 881.0 nM
N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)C2CCOC2)CC3)c1 CHEMBL3918957 IC50 890.0 nM
C[C@H]1CCCN1C(=O)c1cc(C(=O)N[C@@H]2CCc3nc(C(F)(F)F)ccc32)c2n1CCOC2 CHEMBL3949764 IC50 900.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCC(C)(C)C)n2c1COCC2)c1ccccc1 CHEMBL4114087 IC50 900.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2cnccn2)n2c1C(C)OCC2)c1ccccc1 CHEMBL4114634 IC50 900.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCc3c(c(-c4cccc(C#N)c4)nn3Cc3ccc(F)cc3F)C2)cc1 CHEMBL3955607 IC50 906.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C#N)cc1F CHEMBL3907647 IC50 910.0 nM
CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2Cc2cccc(C(F)(F)F)c2)C1 CHEMBL3942769 IC50 911.0 nM
CC(C)[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C#N)nc1 CHEMBL3907130 IC50 920.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ncc(C(F)(F)F)cn1 CHEMBL3962720 IC50 920.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCCC2c2ccn(C)n2)n2c1COCC2)c1ccccc1 CHEMBL4112125 IC50 920.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC2CCCc3nccnc32)n2c1COCC2)c1ccccc1 CHEMBL4109561 IC50 940.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)Nc2nc(C)c(C)s2)c2n1CCOC2)c1ccccc1 CHEMBL4109080 IC50 940.0 nM
CC(=O)N1CCc2c(c(-c3cccc(OC(F)(F)F)c3)nn2C(C)c2ccc(F)cc2)C1 CHEMBL3946771 IC50 947.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL3977956 IC50 970.0 nM
COc1cc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(C)=O)CC3)ccc1F CHEMBL3946004 IC50 975.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCOC[C@@H]2C)c2n1CCOC2)c1ccccc1 CHEMBL3927543 IC50 990.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2c1COCC2)c1cccnc1C(F)(F)F CHEMBL4111408 IC50 1000.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2ccno2)n2c1COCC2)c1ccccc1 CHEMBL4115494 IC50 1000.0 nM
[C-]#[N+]c1ccc([C@@H](CC)NC(=O)c2cc(C(=O)N[C@H](CC)c3ccccc3)c3n2CCOC3)cn1 CHEMBL4109071 IC50 1000.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)NCc2ncco2)c2n1CCOC2)c1ccccc1 CHEMBL4108554 IC50 1000.0 nM
CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1cnc(C#N)c(Cl)c1 CHEMBL3903199 IC50 1000.0 nM
C[C@H]1CCCN1C(=O)c1cc(C(=O)NCc2c(F)cccc2F)c2n1CCOC2 CHEMBL3987153 IC50 1000.0 nM