CN(C)CCc1cccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 CHEMBL4438830 IC50 4.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC5(CCc6ccccc65)CC4)cn3)nccc12 CHEMBL4449500 IC50 5.0 nM
O=C(NCCCc1ccccc1)c1cccc(-c2cc(O)c3ncccc3c2)c1 CHEMBL3785491 IC50 10.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(CCN6CCOCC6)c5)CC4)cn3)nccc12 CHEMBL4440395 IC50 15.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cc(Cl)cc(Cl)c5)CC4)cn3)nccc12 CHEMBL3775894 IC50 17.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(CCN6CCOCC6)cc5)CC4)cn3)nccc12 CHEMBL4466130 IC50 18.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(CN6CCCC6)c5)CC4)cn3)nccc12 CHEMBL4592908 IC50 19.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(-c6ccncc6)cc5)CC4)cn3)nccc12 CHEMBL4590283 IC50 20.0 nM
CN(C)CCc1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 CHEMBL4585876 IC50 20.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(-c6cccnc6)cc5)CC4)cn3)nccc12 CHEMBL4559561 IC50 24.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(-c6cccnc6)c5)CC4)cn3)nccc12 CHEMBL4567766 IC50 27.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccs5)CC4)cn3)nccc12 CHEMBL3775668 IC50 29.0 nM
CC1(c2cccc(Cl)c2)CCN(CCc2cnn(-c3nccc4c(=O)[nH]cnc34)c2)CC1 CHEMBL4573390 IC50 29.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(Cl)c5)CC4)cn3)nccc12 CHEMBL3774537 IC50 31.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(-c6cncnc6)cc5)CC4)cn3)nccc12 CHEMBL4438034 IC50 32.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(F)c5)CC4)cn3)nccc12 CHEMBL4447515 IC50 32.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cc(CN6CCCC6)cc(C(F)(F)F)c5)CC4)cn3)nccc12 CHEMBL4516101 IC50 33.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(-c6ccccn6)c5)CC4)cn3)nccc12 CHEMBL4561958 IC50 33.0 nM
CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O CHEMBL5203308 IC50 33.0 nM
CN(c1ccccc1)c1ccc2c(c1)CCC[C@H]2CNc1cnccc1C(=O)O CHEMBL4216044 IC50 35.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(F)cc5F)CC4)cn3)nccc12 CHEMBL3775121 IC50 36.0 nM
COc1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 CHEMBL3775545 IC50 39.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(C(F)(F)F)c5)CC4)cn3)nccc12 CHEMBL3775548 IC50 39.0 nM
O=c1[nH]cnc2c(-n3cc(C4CCN(CC5CCC5)CC4)cn3)nccc12 CHEMBL4525269 IC50 40.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cc(F)cc(F)c5)CC4)cn3)nccc12 CHEMBL3774456 IC50 41.0 nM
Cc1ccc(C)c2c1CCC21CCN(CCc2cnn(-c3nccc4c(=O)[nH]cnc34)c2)CC1 CHEMBL4435185 IC50 45.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(-c6cncnc6)c5)CC4)cn3)nccc12 CHEMBL4558689 IC50 47.0 nM
CC(C)(C)c1cccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 CHEMBL4520178 IC50 49.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5ccc(Cl)cc5)CC4)cn3)nccc12 CHEMBL3775899 IC50 50.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccncc5)CC4)cn3)nccc12 CHEMBL3775277 IC50 55.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC5(CC4)OCc4ccccc45)cn3)nccc12 CHEMBL4464471 IC50 57.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(F)cc5)CC4)cn3)nccc12 CHEMBL3775953 IC50 61.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5ccc(C(F)(F)F)cc5)CC4)cn3)nccc12 CHEMBL3775516 IC50 62.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cccc(CN6CCOCC6)c5)CC4)cn3)nccc12 CHEMBL4549505 IC50 63.0 nM
COc1cccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 CHEMBL4538741 IC50 67.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5ccc(Cl)c(Cl)c5)CC4)cn3)nccc12 CHEMBL3774940 IC50 68.0 nM
CS(=O)(=O)c1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 CHEMBL3774665 IC50 69.0 nM
N#Cc1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 CHEMBL3775814 IC50 69.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5ccc6c(c5)OCO6)CC4)cn3)nccc12 CHEMBL3775451 IC50 72.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5ccc(F)cc5)CC4)cn3)nccc12 CHEMBL3775040 IC50 79.0 nM
O=C1CCCN1c1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 CHEMBL4522584 IC50 79.0 nM
Nc1nc(-c2cc(C(=O)O)ccn2)cs1 CHEMBL3774692 IC50 83.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(Cl)cc5)CC4)cn3)nccc12 CHEMBL3775977 IC50 86.0 nM
CC(C)c1cccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 CHEMBL4476629 IC50 101.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5cc(CCN6CCOCC6)cc(C(F)(F)F)c5)CC4)cn3)nccc12 CHEMBL4553540 IC50 102.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5ccccc5)CC4)cn3)nccc12 CHEMBL3774392 IC50 118.0 nM
CC(C)COc1cccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 CHEMBL4473678 IC50 145.0 nM
COc1cccc(CC2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 CHEMBL3775465 IC50 149.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccc(-c6ccccn6)cc5)CC4)cn3)nccc12 CHEMBL4572027 IC50 153.0 nM
CN(CCc1cnn(-c2nccc3c(=O)[nH]cnc23)c1)Cc1ccc(Cl)c(Cl)c1 CHEMBL3775145 IC50 165.0 nM
O=C([O-])c1ccnc(CNCc2ccco2)c1 CHEMBL3775362 IC50 170.0 nM
Cc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL3786952 IC50 170.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccccc5Cl)CC4)cn3)nccc12 CHEMBL3775823 IC50 179.0 nM
O=C(O)c1ccc(O)c2ncccc12 CHEMBL1230640 IC50 200.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5cccnc5)CC4)cn3)nccc12 CHEMBL3775956 IC50 207.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(Cc5noc(C6CC6)n5)CC4)cn3)nccc12 CHEMBL3775130 IC50 247.0 nM
CN(CCCc1cnn(-c2nccc3c(=O)[nH]cnc23)c1)Cc1ccc(C#N)cc1 CHEMBL3774922 IC50 260.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccccc5)CC4)cn3)nccc12 CHEMBL3774457 IC50 274.0 nM
Clc1ccc(N/N=C(\c2ccccc2)c2ccccn2)nc1 CHEMBL1982368 IC50 290.0 nM
O=c1[nH]cnc2c(-n3cc(C4CCN(C5CCCC5)CC4)cn3)nccc12 CHEMBL4529932 IC50 302.0 nM
CN(CCc1cnn(-c2nccc3c(=O)[nH]cnc23)c1)Cc1ccc(C#N)cc1 CHEMBL3775135 IC50 340.0 nM
O=C(O)c1ccnc(-c2cscn2)c1 CHEMBL3775933 IC50 350.0 nM
O=c1[nH]cnc2c(-n3cc(C4CCN(CC5CC5)CC4)cn3)nccc12 CHEMBL4532069 IC50 372.0 nM
CN(CCc1cnn(-c2nccc3c(=O)[nH]cnc23)c1)Cc1ccc(F)cc1 CHEMBL3774747 IC50 390.0 nM
CN(CCc1cnn(-c2nccc3c(=O)[nH]cnc23)c1)Cc1ccc(S(C)(=O)=O)cc1 CHEMBL3774701 IC50 400.0 nM
CCN1CCC(c2cnn(-c3nccc4c(=O)[nH]cnc34)c2)CC1 CHEMBL4560811 IC50 455.0 nM
CC(C)CN1CCC(c2cnn(-c3nccc4c(=O)[nH]cnc34)c2)CC1 CHEMBL4445652 IC50 497.0 nM
CC(C)N1CCC(c2cnn(-c3nccc4c(=O)[nH]cnc34)c2)CC1 CHEMBL4455283 IC50 504.0 nM
Cn1cc(CN2CCC(c3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cn1 CHEMBL4483792 IC50 573.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCCCC4)cn3)nccc12 CHEMBL3775500 IC50 650.0 nM
COC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL278315 IC50 700.0 nM
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NCCN(C)C)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O CHEMBL383824 IC50 700.0 nM
C=CCNC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL109480 IC50 700.0 nM
O=c1[nH]cnc2c(-n3cc(CCN4CCCC4)cn3)nccc12 CHEMBL3774710 IC50 750.0 nM
CN1CCC(c2cnn(-c3nccc4c(=O)[nH]cnc34)c2)CC1 CHEMBL4483780 IC50 820.0 nM
O=c1[nH]cnc2cnccc12 CHEMBL3770256 IC50 1000.0 nM