CN(c1ccccc1)c1ccc2c(c1)CCC[C@H]2CNc1cnccc1C(=O)O CHEMBL4216044 EC50 1.3 nM
O=C(O)c1ccnc(C(=O)O)c1 CHEMBL316034 Ki 2.2 nM
CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C(C)C)NC1=O CHEMBL4204694 IC50 2.2 nM
CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C(C)C)NC1=O CHEMBL5203487 IC50 2.2 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccccc2)c1 CHEMBL4225358 IC50 5.0 nM
COc1ccc2c(c1)CCC[C@H]2CNc1cnccc1C(=O)O CHEMBL4211946 IC50 6.0 nM
O=C(O)c1ccncc1NC[C@@H]1CCCc2ccccc21 CHEMBL4207583 IC50 8.0 nM
COc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1 CHEMBL1517074 IC50 8.0 nM
Cn1nc(-c2ccc(C#N)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL4648732 IC50 11.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4209038 IC50 12.0 nM
O=C(O)c1ccncc1NCC1CCCc2ccccc21 CHEMBL4204375 IC50 12.0 nM
N#Cc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4229271 IC50 14.0 nM
CN(C)c1ccccc1-c1nc2c(=O)n(C)c(=O)nc-2n(C)n1 CHEMBL4646339 IC50 16.0 nM
O=C(O)c1ccncc1NC[C@@H]1CCCc2cc(Oc3ccccc3)ccc21 CHEMBL4207071 IC50 17.0 nM
O=C(O)c1ccncc1NC[C@@H]1CCCc2cc(Sc3ccccc3)ccc21 CHEMBL4216399 EC50 19.0 nM
CN(C)CCc1cnn(-c2cc(C(=O)O)ccn2)c1OCc1ccc(F)cc1 CHEMBL4228806 IC50 19.0 nM
Cn1nc(-c2ccncc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1316847 IC50 19.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL4205183 IC50 22.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4218675 IC50 23.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC1=O CHEMBL4206181 IC50 23.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)cc2)c1 CHEMBL4225013 IC50 24.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4215000 IC50 27.0 nM
Cn1nc(Cc2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1394266 IC50 29.0 nM
O=C(O)c1ccnc(-c2ccc[nH]2)c1 CHEMBL5203320 Ki 31.0 nM
CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O CHEMBL5203308 IC50 33.0 nM
Cc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL3786952 IC50 35.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4205285 IC50 38.0 nM
COc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4228292 IC50 38.0 nM
Cn1nc(-c2ccc(S(N)(=O)=O)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL4640696 IC50 42.0 nM
O=C(O)c1ccnc(-c2cc(NC(=O)c3ccc(O)cc3)ccc2O)c1 CHEMBL3775262 Ki 43.2 nM
CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O CHEMBL4203936 IC50 46.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4218774 IC50 53.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2)c1 CHEMBL3785832 IC50 54.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL4211201 IC50 55.0 nM
O=C(O)c1ccncc1NCc1ccsc1 CHEMBL3774552 pIC50 63.1 nM
O=C(O)c1ccncc1NCc1cccs1 CHEMBL3774859 pIC50 63.1 nM
Cc1cc(C(=O)Nc2ccc(O)c(-c3cc(C(=O)O)ccn3)c2)no1 CHEMBL3775867 IC50 65.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4208277 IC50 65.0 nM
COc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4228610 IC50 68.0 nM
COc1ccc(CC(=O)Nc2ccc(O)c(-c3cc(C(=O)O)ccn3)c2)cc1 CHEMBL3775563 IC50 69.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccnc(-c3cc(C(=O)O)ccn3)c2)cc1 CHEMBL3108958 IC50 70.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2OCc2ccccc2)c1 CHEMBL4227526 IC50 74.0 nM
CCOc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4229264 IC50 78.0 nM
O=C(O)c1ccncc1NCc1ccco1 CHEMBL3775237 IC50 79.0 nM
Cc1ccsc1CNc1cnccc1C(=O)O CHEMBL3775889 pIC50 79.43 nM
Cn1nc(-c2ccc(F)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1438218 IC50 81.0 nM
Cc1csc(CNc2cnccc2C(=O)O)c1 CHEMBL3775834 pIC50 100.0 nM
O=C(O)c1ccncc1NCc1cscn1 CHEMBL3775439 pIC50 100.0 nM
O=C(O)c1ccncc1NCc1ccccc1 CHEMBL3775612 pIC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(OCC2CC2)cc1 CHEMBL3787664 IC50 100.0 nM
O=C(O)c1ccncc1NCC1CCCc2cc(Oc3ccccc3)ccc21 CHEMBL3787556 IC50 100.0 nM
O=C(O)c1ccncc1Nc1nn(C2CCCC2)c2ccc(F)cc12 CHEMBL3785470 IC50 100.0 nM
Cn1nc(Nc2cnccc2C(=O)O)c2cccnc21 CHEMBL3786617 IC50 100.0 nM
Cn1cnc(-c2nccc3c(O)nc(OCCCC(F)(F)F)nc23)c1 CHEMBL3787534 IC50 100.0 nM
CCOC(=O)c1ccnc(CNCC(=O)N(CC)CCN(C)C)c1 CHEMBL3786593 IC50 100.0 nM
Cc1cc(O)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4286275 IC50 100.0 nM
O=C(O)c1ccnc(-n2nc(C3CC3)cc2O)c1 CHEMBL4293252 IC50 100.0 nM
Cc1nn(-c2cc(C(=O)O)ccn2)c(O)c1C CHEMBL4292883 IC50 100.0 nM
CCCc1cc(O)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4287794 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2O)c1 CHEMBL4287317 IC50 100.0 nM
Cc1ccc(-c2ccnn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4227799 IC50 100.0 nM
Cc1cccc(-c2ccnn2-c2cc(C(=O)O)ccn2)c1 CHEMBL4283282 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc(F)cc2F)c1 CHEMBL4228902 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc(F)c(F)c2)c1 CHEMBL4228839 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2-c2cccc(F)c2)c1 CHEMBL4227668 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2-c2cccc(O)c2)c1 CHEMBL4228384 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc(O)cc2)c1 CHEMBL4227544 IC50 100.0 nM
Cc1ccc(-c2ccnn2-c2cc(C(=O)O)ccn2)cc1O CHEMBL4228321 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc(F)cc2)c1 CHEMBL4226553 IC50 100.0 nM
Cc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4280874 IC50 100.0 nM
O=C(O)c1ccnc(-n2ccc(CCc3ccccc3)n2)c1 CHEMBL4281202 IC50 100.0 nM
Cc1cc(OCc2ccccc2)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4287797 IC50 100.0 nM
CCCCc1ccn(-c2cc(C(=O)O)ccn2)n1 CHEMBL4287102 IC50 100.0 nM
Cn1ncc2ccc(COc3ccnn3-c3cc(C(=O)O)ccn3)cc21 CHEMBL4290631 IC50 100.0 nM
Cn1cc2cc(COc3ccnn3-c3cc(C(=O)O)ccn3)ccc2n1 CHEMBL4289609 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)c(F)c2)c1 CHEMBL4289229 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(C(F)(F)F)cc2)c1 CHEMBL4228544 IC50 100.0 nM
CCc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4227237 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2cccnc2)c1 CHEMBL4279283 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCC2CCC(F)(F)CC2)c1 CHEMBL4282732 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(C3CC3)cc2)c1 CHEMBL4224779 IC50 100.0 nM
CC(Oc1ccnn1-c1cc(C(=O)O)ccn1)c1ccc(F)cc1 CHEMBL4225839 IC50 100.0 nM
Cc1cnn(-c2cc(C(=O)O)ccn2)c1OCc1ccc(F)cc1 CHEMBL4225810 IC50 100.0 nM
CCc1cnn(-c2cc(C(=O)O)ccn2)c1OCc1ccc(F)cc1 CHEMBL4225915 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)cc2F)c1 CHEMBL4277880 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)c(Cl)c2)c1 CHEMBL4285149 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2Cl)c1 CHEMBL4284664 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)c(C(F)(F)F)c2)c1 CHEMBL4277625 IC50 100.0 nM
CCc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)cc1Cl CHEMBL4283150 IC50 100.0 nM
CCc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)cc1F CHEMBL4291649 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2OCC2CC2)c1 CHEMBL4225515 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2OCC(F)(F)F)c1 CHEMBL4292430 IC50 100.0 nM
COCCOc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4293804 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)cc2OCc2ccc(F)cc2)c1 CHEMBL4290069 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2cccc3c2OCC3)c1 CHEMBL4279800 IC50 100.0 nM
CC1(C)Cc2cccc(COc3ccnn3-c3cc(C(=O)O)ccn3)c2O1 CHEMBL4285045 IC50 100.0 nM
Cc1cc(C#N)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4284014 IC50 100.0 nM
CCc1cc(C#N)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4287035 IC50 100.0 nM
Cc1cc(F)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4279777 IC50 100.0 nM
CCc1cc(F)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4278739 IC50 100.0 nM
Cc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)c(F)c1 CHEMBL4282868 IC50 100.0 nM
Cc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)c(C)c1 CHEMBL4289921 IC50 100.0 nM
COc1cc(C)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4288884 IC50 100.0 nM
Cc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)c(C#N)c1 CHEMBL4278583 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)c(OCc3ccc(F)cc3)c2)c1 CHEMBL4289000 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)c(OCc3ccc(F)cc3)c2)c1 CHEMBL4292686 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)c(OCC3CC3)c2)c1 CHEMBL4287561 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)c(OCC(F)(F)F)c2)c1 CHEMBL4288613 IC50 100.0 nM
Cc1cc(Br)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4281578 IC50 100.0 nM
COc1cc(Br)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4282610 IC50 100.0 nM
Cc1cc(I)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4289769 IC50 100.0 nM
COc1cc(I)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4290799 IC50 100.0 nM
O=C(O)c1ccnc(-n2nccc2OC2CCc3cc(F)ccc32)c1 CHEMBL4291175 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1Br CHEMBL4278863 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(-n2cccn2)cc1 CHEMBL4286418 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(C2(CO)CC2)cc1 CHEMBL4290498 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(N2CCCC2)cc1 CHEMBL4278099 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)cc1 CHEMBL4279120 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1cccc(Cl)c1 CHEMBL4280936 IC50 100.0 nM
C#Cc1ccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)cc1 CHEMBL4284112 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc2cc[nH]c2c1 CHEMBL4285037 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(F)cc1 CHEMBL4284008 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1cccc(F)c1 CHEMBL4293976 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)c(Cl)c1 CHEMBL4286705 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)c(F)c1 CHEMBL4285705 IC50 100.0 nM
COc1cc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)ccc1Cl CHEMBL4279368 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)c(C(F)(F)F)c1 CHEMBL4283146 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)cc1Cl CHEMBL4290844 IC50 100.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(C2(C(F)(F)F)CC2)cc1 CHEMBL4287547 IC50 100.0 nM
CCCn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)c(F)c1 CHEMBL4288587 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(Cc3ccccn3)cn2)c1 CHEMBL4280355 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CC3CCCO3)cn2)c1 CHEMBL4285330 IC50 100.0 nM
CN(CCn1cnc(-c2cc(C(=O)O)ccn2)c1)c1ccccc1 CHEMBL4286972 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN3CCCC3=O)cn2)c1 CHEMBL4290173 IC50 100.0 nM
c1cc(-c2nn[nH]n2)cc(-c2cn(CCN3CCCC3)cn2)n1 CHEMBL4283417 IC50 100.0 nM
CN(CCn1cnc(-c2cc(C(=O)NC#N)ccn2)c1)CC1CC1 CHEMBL4278375 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN(Cc3ccc(Cl)cc3)C3CC3)cn2)c1 CHEMBL4284739 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN(Cc3ccc(Cl)c(Cl)c3)C3CC3)cn2)c1 CHEMBL4285118 IC50 100.0 nM
CN(CCn1cnc(-c2cc(C(=O)O)ccn2)c1)c1ccc(Cl)cc1 CHEMBL4286102 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN3CCCc4ccccc43)cn2)c1 CHEMBL4289159 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN3CCCc4cc(Cl)ccc43)cn2)c1 CHEMBL4290188 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN3CCCc4cc(F)ccc43)cn2)c1 CHEMBL4292346 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCN3CCc4cc(F)ccc43)cn2)c1 CHEMBL4293359 IC50 100.0 nM
COc1ccccc1CCn1cnc(-c2cc(C(=O)O)ccn2)c1 CHEMBL4280613 IC50 100.0 nM
Cc1ccccc1CCn1cnc(-c2cc(C(=O)O)ccn2)c1 CHEMBL4283431 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCc3ccccc3Cl)cn2)c1 CHEMBL4282361 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(C3Cc4ccccc4C3)cn2)c1 CHEMBL4278227 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(Cc3ccccc3)cn2)c1 CHEMBL4290636 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(Cc3ccc(F)cc3)cn2)c1 CHEMBL4282667 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(Cc3ccccc3F)cn2)c1 CHEMBL4281591 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(Cc3cccc(F)c3)cn2)c1 CHEMBL4279029 IC50 100.0 nM
CC(Cc1ccccc1)n1cnc(-c2cc(C(=O)O)ccn2)c1 CHEMBL4289724 IC50 100.0 nM
CCC(c1ccccc1)n1cnc(-c2cc(C(=O)O)ccn2)c1 CHEMBL4290755 IC50 100.0 nM
CC(C)C(c1ccccc1)n1cnc(-c2cc(C(=O)O)ccn2)c1 CHEMBL4285687 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(C3CCc4c(F)cccc43)cn2)c1 CHEMBL4295253 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCc3cccc4ccccc34)cn2)c1 CHEMBL4293159 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCc3cccc(Cl)c3)cn2)c1 CHEMBL4292153 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CCC3CCCCC3)cn2)c1 CHEMBL4289043 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CC3CCCCC3)cn2)c1 CHEMBL4277693 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(CC3CCCc4ccccc43)cn2)c1 CHEMBL4287682 IC50 100.0 nM
O=C(O)c1ccnc(-c2cn(Cc3cccc(C(F)(F)F)c3)cn2)c1 CHEMBL4286649 IC50 100.0 nM
O=C(O)c1ccnc(-c2ncn(CCc3ccccc3Cl)c2-c2ccc(F)cc2)c1 CHEMBL4281614 IC50 100.0 nM
O=C(O)c1ccnc(-c2ncn(CC3CC3)c2-c2ccc(F)cc2)c1 CHEMBL4282658 IC50 100.0 nM
O=C(O)c1ccnc(NCc2cccc(F)c2)c1 CHEMBL5268189 IC50 100.0 nM
O=C(O)c1ccncc1NCc1ccn[nH]1 CHEMBL3775716 pIC50 125.89 nM
O=C(O)c1ccncc1NCC1CC1 CHEMBL3775957 pIC50 125.89 nM
CCCCNc1cnccc1C(=O)O CHEMBL3774403 pIC50 125.89 nM
O=C(O)c1ccncc1NCC1CCCCC1 CHEMBL3774834 pIC50 125.89 nM
Cn1nc(-c2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1527391 IC50 130.0 nM
COc1cccc(CC(=O)Nc2ccc(O)c(-c3cc(C(=O)O)ccn3)c2)c1 CHEMBL3775272 IC50 140.0 nM
COCC(=O)Nc1ccc(O)c(-c2cc(C(=O)O)ccn2)c1 CHEMBL3775380 IC50 140.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC1=O CHEMBL4213743 IC50 151.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O CHEMBL4218482 IC50 154.0 nM
O=C(O)c1ccncc1NCCCCc1ccccc1 CHEMBL3774408 pIC50 158.49 nM
CC(C)CNc1cnccc1C(=O)O CHEMBL3775952 pIC50 158.49 nM
CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4208111 IC50 164.0 nM
O=C(Cc1cccc(Br)c1)Nc1ccc(O)c(-c2cc(C(=O)O)ccn2)c1 CHEMBL3775162 IC50 170.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4206582 IC50 173.0 nM
O=C(O)c1ccnc(-c2ccccn2)c1 CHEMBL3621852 pIC50 199.53 nM
O=c1[nH]c(Oc2cccc(O)c2)nc2cnccc12 CHEMBL3770723 pIC50 199.53 nM
Cc1ccc(CNc2cnccc2C(=O)O)s1 CHEMBL3774545 pIC50 199.53 nM
O=C(O)c1ccncc1NCC1CCCC1 CHEMBL3775175 pIC50 199.53 nM
O=C(O)c1ccncc1NCCCc1ccccc1 CHEMBL3774399 pIC50 199.53 nM
O=C(O)c1ccc(O)c2ncccc12 CHEMBL1230640 IC50 200.0 nM
Cn1nc(-c2ccc(O)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL4649004 IC50 242.0 nM
Clc1ccc(N/N=C(\c2ccccc2)c2ccccn2)nc1 CHEMBL1982368 IC50 290.0 nM
Cc1cccc(CNc2cnccc2C(=O)O)c1C CHEMBL3775522 pIC50 316.23 nM
O=C(Cc1ccccc1)Nc1cnccc1C(=O)O CHEMBL3775431 pIC50 316.23 nM
O=C(CCc1ccccc1)Nc1cnccc1C(=O)O CHEMBL3775245 pIC50 316.23 nM
CCCNc1cnccc1C(=O)O CHEMBL3774734 pIC50 316.23 nM
N#C/C(N=Nc1ccccc1O)=N/Nc1ccccc1O CHEMBL1982032 AC50 387.8 nM
O=c1[nH]c(Oc2cnn(-c3ccccc3)c2)nc2cnccc12 CHEMBL3769522 pIC50 398.11 nM
O=c1[nH]c(Oc2cnn(C3CCCCC3)c2)nc2cnccc12 CHEMBL3769744 pIC50 398.11 nM
Cn1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1 CHEMBL3769647 pIC50 398.11 nM
O=c1[nH]c(Oc2cn[nH]c2)nc2cnccc12 CHEMBL3770916 pIC50 398.11 nM
O=c1[nH]c(Oc2ccc(Cl)c(O)c2)nc2cnccc12 CHEMBL3770740 pIC50 398.11 nM
O=C(CCCc1ccccc1)Nc1cnccc1C(=O)O CHEMBL3774845 pIC50 398.11 nM
Cc1nc2c(=O)n(C)c(=O)nc-2n(C)n1 CHEMBL601757 AC50 424.5 nM
O=C(Cc1ccccc1)Nc1ccc(O)c(-c2cc(C(=O)O)ccn2)c1 CHEMBL3774814 IC50 430.0 nM
O=C(O)c1ccnc(-c2cc(NC(=O)c3cccc(O)c3)ccc2O)c1 CHEMBL3774611 IC50 460.0 nM
CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC1=O CHEMBL4209558 IC50 466.0 nM
C=CCN(CC=C)Cc1c(O)ccc2c1oc(=O)c1ccccc12 CHEMBL1521897 AC50 480.4 nM
Cn1ncnc2c(=O)n(C)c(=O)nc1-2 CHEMBL578512 IC50 500.0 nM
O=c1[nH]c(Oc2cnn(Cc3ccccc3)c2)nc2cnccc12 CHEMBL3771180 pIC50 501.19 nM
O=c1[nH]c(Oc2cnn(C3CCCCCC3)c2)nc2cnccc12 CHEMBL3769853 pIC50 501.19 nM
CC(C)n1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1 CHEMBL3769840 pIC50 501.19 nM
O=c1[nH]c(Oc2ccc(Cl)cc2)nc2cnccc12 CHEMBL3770190 pIC50 501.19 nM
O=c1[nH]c(Oc2cccnc2)nc2cnccc12 CHEMBL3770926 pIC50 501.19 nM
NCCCNc1cnccc1C(=O)O CHEMBL3774560 pIC50 501.19 nM
O=C(O)c1ccnc(-c2cc(NCc3cccc4c3OCO4)ccc2O)c1 CHEMBL3774705 IC50 560.0 nM
CSCC[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](C)N)CSSC[C@@H](C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O CHEMBL3787020 IC50 600.0 nM
O=c1[nH]c(Oc2cnn(Cc3cccnc3)c2)nc2cnccc12 CHEMBL3770030 pIC50 630.96 nM
COc1cccc(Cn2cc(Oc3nc4cnccc4c(=O)[nH]3)cn2)c1 CHEMBL3769669 pIC50 630.96 nM
O=c1[nH]c(Oc2cnn(CC3CCCCC3)c2)nc2cnccc12 CHEMBL3771198 pIC50 630.96 nM
O=c1[nH]c(Oc2cnn(C3CCCC3)c2)nc2cnccc12 CHEMBL3769724 pIC50 630.96 nM
O=c1[nH]c(Oc2ccccc2)nc2cnccc12 CHEMBL3771289 pIC50 630.96 nM
Nc1cnccc1C(=O)O CHEMBL1383671 pIC50 630.96 nM
CC(Nc1cnccc1C(=O)O)c1ccccc1 CHEMBL3775110 pIC50 630.96 nM
Cc1ccc(C)c(CNc2cnccc2C(=O)O)c1 CHEMBL3774487 pIC50 630.96 nM
Clc1ccc(/N=c2\ssnc2Cl)nc1 CHEMBL2000342 AC50 668.9 nM
COC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL278315 IC50 700.0 nM
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NCCN(C)C)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O CHEMBL383824 IC50 700.0 nM
C=CCNC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL109480 IC50 700.0 nM
O=c1[nH]cc(/N=C/c2cc(Cl)cc(Cl)c2O)c(=O)[nH]1 CHEMBL2006750 AC50 749.5 nM
Cn1nccc1CNc1ccc(O)c(-c2cc(C(=O)O)ccn2)c1 CHEMBL3774573 IC50 770.0 nM
CCSc1nc2cnccc2c(=O)[nH]1 CHEMBL3770812 pIC50 794.33 nM
CC(=O)C1=C(c2ccccc2)N(C(C)=O)n2c(C)nnc2S1 CHEMBL1438779 AC50 799.8 nM
Oc1ccc(/C=N/Nc2ncc(Br)cn2)c(O)c1 CHEMBL3199539 AC50 828.7 nM
Cn1nc(-c2ccccn2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1463659 AC50 872.5 nM
CC1CN(Cc2c(O)ccc3c2oc(=O)c2ccccc23)CC(C)O1 CHEMBL1426955 AC50 949.9 nM
CN(C)CCCCCCCCC(=O)N(O)CCC(=O)O CHEMBL1215519 IC50 1000.0 nM
CN(C)CCCCCCCCC(=O)N(O)CCC(=O)O CHEMBL1229308 IC50 1000.0 nM
CC(C)c1ccc(Oc2nc3cnccc3c(=O)[nH]2)cn1 CHEMBL3769511 pIC50 1000.0 nM
CCOc1nc2cnccc2c(=O)[nH]1 CHEMBL3770515 pIC50 1000.0 nM
COc1ccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)cc1 CHEMBL3786803 IC50 1000.0 nM
O=C(O)c1ccnc(-n2ncc(CCO)c2OCc2ccc(F)cc2)c1 CHEMBL3786579 IC50 1000.0 nM
CC(C)Cn1nc(Nc2cnccc2C(=O)NC#N)c2cc(F)ccc21 CHEMBL3787438 IC50 1000.0 nM
CCc1c(C)nc2c(C#N)cnn2c1OC CHEMBL3786528 IC50 1000.0 nM
Cc1nn(-c2cc(C(=O)O)ccn2)c(O)c1-c1ccccc1 CHEMBL4293636 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(-c3ccccc3F)cc2O)c1 CHEMBL4288830 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3ccccc3)cc2O)c1 CHEMBL4276814 IC50 1000.0 nM
COCc1cc(O)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4277756 IC50 1000.0 nM
CS(=O)(=O)c1ccc(-c2ccnn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4227075 IC50 1000.0 nM
COc1cc(-c2ccnn2-c2cc(C(=O)O)ccn2)ccc1C CHEMBL4226861 IC50 1000.0 nM
COc1cc(-c2ccnn2-c2cc(C(=O)O)ccn2)ccc1Cl CHEMBL4225665 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc(Cl)c(O)c2)c1 CHEMBL4288537 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc3cn[nH]c3c2)c1 CHEMBL4284855 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccccc2)c1 CHEMBL4226822 IC50 1000.0 nM
CS(=O)(=O)c1ccc(-c2ccnn2-c2cc(C(=O)O)ccn2)cc1O CHEMBL4280506 IC50 1000.0 nM
Cc1ccc(-c2cc(C)nn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4279432 IC50 1000.0 nM
CCc1cc(-c2ccc(C)cc2)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4284610 IC50 1000.0 nM
O=C(O)c1ccnc(-n2ccc(Cc3ccccc3)n2)c1 CHEMBL4284987 IC50 1000.0 nM
COc1cc(C)nn1-c1cc(C(=O)O)ccn1 CHEMBL4285308 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2-c2ccc(Br)cc2)c1 CHEMBL4282036 IC50 1000.0 nM
CN(C)c1ccc(-c2ccnn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4283065 IC50 1000.0 nM
Cc1ccc(-c2cc(N)nn2-c2cc(C(=O)O)ccn2)cc1 CHEMBL4286858 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc3cn[nH]c3c2)c1 CHEMBL4285840 IC50 1000.0 nM
CCCCOc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4287296 IC50 1000.0 nM
CC(C)COc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4281159 IC50 1000.0 nM
CC(C)Oc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4282124 IC50 1000.0 nM
CCC(C)Oc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4292444 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2OCc2ccc(F)cc2)c1 CHEMBL4289695 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)cc2/C=C/c2ccc(F)cc2)c1 CHEMBL4291083 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2/C=C/c2ccc(F)cc2)c1 CHEMBL4294132 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(F)cc2CCc2ccc(F)cc2)c1 CHEMBL4295216 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2CCc2ccc(F)cc2)c1 CHEMBL4278760 IC50 1000.0 nM
CCc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4285436 IC50 1000.0 nM
Cc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)c(Cl)c1 CHEMBL4283926 IC50 1000.0 nM
CCc1cc(C)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL4279612 IC50 1000.0 nM
CC(Oc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1)c1ccccc1 CHEMBL4293050 IC50 1000.0 nM
CC(Oc1cc(F)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1)c1ccccc1 CHEMBL4294087 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OC2CCc3cc(Cl)ccc32)c1 CHEMBL4287020 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OC2CCCc3cc(F)ccc32)c1 CHEMBL4287394 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OC2CCCc3cc(Cl)ccc32)c1 CHEMBL4288436 IC50 1000.0 nM
CCc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)c(Cl)c1 CHEMBL4291477 IC50 1000.0 nM
CCc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)c(F)c1 CHEMBL4292524 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(C3CC3)cc2Cl)c1 CHEMBL4294656 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(C3CC3)cc2F)c1 CHEMBL4279637 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(C3CC3)c(Cl)c2)c1 CHEMBL4283497 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nccc2OCc2ccc(C3CC3)c(F)c2)c1 CHEMBL4287567 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(-c3ccc(Cl)cc3)cc2O)c1 CHEMBL4288934 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(-c3cccc(Cl)c3)cc2O)c1 CHEMBL4287890 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(C3CCCC3)cc2O)c1 CHEMBL4284863 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3c(F)cccc3F)cc2O)c1 CHEMBL4283852 IC50 1000.0 nM
CC(c1ccccc1)c1cc(O)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4277650 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3ccccc3Cl)cc2O)c1 CHEMBL4292495 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3cccc(Cl)c3)cc2O)c1 CHEMBL4286778 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3ccc(Cl)cc3)cc2O)c1 CHEMBL4290497 IC50 1000.0 nM
CC(c1ccccc1)c1cc(O)n(-c2cc(-c3nnn[nH]3)ccn2)n1 CHEMBL4285441 IC50 1000.0 nM
Oc1cc(Cc2ccccc2Cl)nn1-c1cc(-c2nnn[nH]2)ccn1 CHEMBL4286417 IC50 1000.0 nM
Oc1cc(Cc2cccc(Cl)c2)nn1-c1cc(-c2nnn[nH]2)ccn1 CHEMBL4294944 IC50 1000.0 nM
Oc1cc(Cc2ccc(Cl)cc2)nn1-c1cc(-c2nnn[nH]2)ccn1 CHEMBL4277439 IC50 1000.0 nM
CC(C)(c1ccc(Cl)cc1)c1cc(O)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4290864 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(C3(c4ccc(Cl)cc4)CC3)cc2O)c1 CHEMBL4291898 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3cc(Cl)cc(Cl)c3)cc2O)c1 CHEMBL4281922 IC50 1000.0 nM
Cc1cc(F)ccc1Cc1cc(O)n(-c2cc(C(=O)O)ccn2)n1 CHEMBL4277749 IC50 1000.0 nM
Cc1ccc(Cc2cc(O)n(-c3cc(C(=O)O)ccn3)n2)c(F)c1 CHEMBL4288311 IC50 1000.0 nM
O=C(O)c1ccnc(-n2nc(Cc3ccc(F)cc3F)cc2O)c1 CHEMBL4284690 IC50 1000.0 nM
FC(F)(F)c1ccccc1CCn1cnc(-c2cc(-c3nn[nH]c3C(F)(F)F)ccn2)c1 CHEMBL4278662 IC50 1000.0 nM
COc1ccc(Cn2cnc(-c3cc(-c4nn[nH]c4C(F)(F)F)ccn3)c2)cc1 CHEMBL4277458 IC50 1000.0 nM
FC(F)(F)c1[nH]nnc1-c1ccnc(-c2cn(CC3CCc4ccccc43)cn2)c1 CHEMBL4289252 IC50 1000.0 nM
Fc1ccc2c(c1)C(n1cnc(-c3cc(-c4nn[nH]c4C(F)(F)F)ccn3)c1)CC2 CHEMBL4283265 IC50 1000.0 nM
Cc1ccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)cc1O CHEMBL4292111 IC50 1000.0 nM
Cc1ccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)cc1 CHEMBL4288406 IC50 1000.0 nM
CCc1ccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)cc1 CHEMBL4288034 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(C(F)(F)F)cc1 CHEMBL4286983 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(C2CC2)cc1 CHEMBL4284869 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(C(C)(C)C)cc1 CHEMBL4283867 IC50 1000.0 nM
CNC(=O)c1cccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)c1 CHEMBL4290866 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1cccc(CO)c1 CHEMBL4293936 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(OC(F)(F)F)cc1 CHEMBL4288145 IC50 1000.0 nM
CCOc1ccc(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)cc1 CHEMBL4285443 IC50 1000.0 nM
COCC1(c2ccc(-c3c(-c4cc(C(=O)O)ccn4)ncn3C)cc2)CC1 CHEMBL4292915 IC50 1000.0 nM
Cc1cc(Cl)ccc1-c1c(-c2cc(C(=O)O)ccn2)ncn1C CHEMBL4279490 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)cc1C(F)(F)F CHEMBL4294329 IC50 1000.0 nM
CCOc1cc(Cl)ccc1-c1c(-c2cc(C(=O)O)ccn2)ncn1C CHEMBL4277960 IC50 1000.0 nM
COCCCn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)c(F)c1 CHEMBL4283531 IC50 1000.0 nM
COCCn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(Cl)c(F)c1 CHEMBL4284538 IC50 1000.0 nM
O=C(O)c1ccnc(-c2cn(CCn3cccn3)cn2)c1 CHEMBL4290028 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)c(C(=O)NCc2ccccc2)c1 CHEMBL4285425 IC50 1000.0 nM
CC(C)(Cn1cnc(-c2cc(C(=O)O)ccn2)c1)c1ccccc1Cl CHEMBL4281219 IC50 1000.0 nM
O=C(O)c1ccnc(-c2cn(C3CCc4ccc(F)cc43)cn2)c1 CHEMBL4286665 IC50 1000.0 nM
O=C(O)c1ccnc(-c2cn(Cc3cccc(-c4ccccc4)c3)cn2)c1 CHEMBL4291057 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1ccc(F)cc1OCC1CC1 CHEMBL4291787 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1cc(F)c(F)cc1OCC1CC1 CHEMBL4288068 IC50 1000.0 nM
Cn1cnc(-c2cc(C(=O)O)ccn2)c1-c1c(F)cccc1OCC1CC1 CHEMBL4280440 IC50 1000.0 nM
Cc1ccc(OCC2CC2)c(-c2c(-c3cc(C(=O)O)ccn3)ncn2C)c1 CHEMBL4279372 IC50 1000.0 nM
O=C(O)c1ccnc(-c2ncn(CC3CC3)c2-c2ccc(Cl)cc2)c1 CHEMBL4277801 IC50 1000.0 nM
O=C(O)c1ccnc(-c2ncn(Cc3ccccc3Cl)c2-c2ccc(F)cc2)c1 CHEMBL4278827 IC50 1000.0 nM
CCOc1ccccc1CCn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4294639 IC50 1000.0 nM
Clc1ccccc1Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4277136 IC50 1000.0 nM
Clc1cccc(Cn2cnc(-c3cc(-c4nn[nH]n4)ccn3)c2)c1 CHEMBL4277523 IC50 1000.0 nM
Clc1ccc(Cn2cnc(-c3cc(-c4nn[nH]n4)ccn3)c2)cc1 CHEMBL4281241 IC50 1000.0 nM
Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CCc2ccccc2Cl)cc1 CHEMBL4287370 IC50 1000.0 nM
Clc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CCc2ccccc2Cl)cc1 CHEMBL4288414 IC50 1000.0 nM
Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CC(F)(F)F)cc1 CHEMBL4287099 IC50 1000.0 nM
Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CC2CC2)cc1 CHEMBL4286061 IC50 1000.0 nM
Clc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CC2CC2)cc1 CHEMBL4290874 IC50 1000.0 nM
Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2Cc2ccccc2Cl)cc1 CHEMBL4289848 IC50 1000.0 nM
CC(=O)OCn1nnc(-c2ccnc(-c3ncn(Cc4ccccc4Cl)c3-c3ccc(F)cc3)c2)n1 CHEMBL4289480 IC50 1000.0 nM
CC(C)(C)C(=O)OCn1nnc(-c2ccnc(-c3ncn(Cc4ccccc4Cl)c3-c3ccc(F)cc3)c2)n1 CHEMBL4285770 IC50 1000.0 nM
FC(F)(F)c1ccccc1CCn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4285453 IC50 1000.0 nM
Clc1ccccc1CCn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4284366 IC50 1000.0 nM
c1ccc2c(CCn3cnc(-c4cc(-c5nn[nH]n5)ccn4)c3)cccc2c1 CHEMBL4282244 IC50 1000.0 nM
c1ccc2c(c1)CCCC2Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4281193 IC50 1000.0 nM
CCC(c1ccccc1)n1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4288012 IC50 1000.0 nM
CC(C)C(c1ccccc1)n1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4289071 IC50 1000.0 nM
c1ccc2c(c1)CCC(Cn1cnc(-c3cc(-c4nn[nH]n4)ccn3)c1)C2 CHEMBL4283981 IC50 1000.0 nM
c1ccc2c(c1)CC(Cn1cnc(-c3cc(-c4nn[nH]n4)ccn3)c1)C2 CHEMBL4285015 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)cc1OCc1ccccc1 CHEMBL4287690 IC50 1000.0 nM
CCCCOc1cc(F)ccc1-c1c(-c2cc(-c3nn[nH]n3)ccn2)ncn1C CHEMBL4283600 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)cc1OCC1CC1 CHEMBL4286301 IC50 1000.0 nM
Clc1cccc(Cl)c1Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4287334 IC50 1000.0 nM
FC(F)(F)COc1ccccc1Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4282270 IC50 1000.0 nM
CC(C)COc1ccccc1Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4283306 IC50 1000.0 nM
FC(F)(F)c1cccc(Cn2cnc(-c3cc(-c4nn[nH]n4)ccn3)c2)c1Cl CHEMBL4290010 IC50 1000.0 nM
c1ccc2c(Cn3cnc(-c4cc(-c5nn[nH]n5)ccn4)c3)cccc2c1 CHEMBL4288987 IC50 1000.0 nM
FC(F)(F)Oc1ccccc1Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4294072 IC50 1000.0 nM
CC(c1ccccc1Cl)n1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1 CHEMBL4290362 IC50 1000.0 nM
Clc1cccc(Cn2cnc(-c3cc(-c4nn[nH]n4)ccn3)c2)c1Cl CHEMBL4276929 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)c(OCC(F)(F)F)c1 CHEMBL4294432 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)c(OCc2ccccc2)c1 CHEMBL4291725 IC50 1000.0 nM
Cn1cnc(-c2cc(C#N)ccn2)c1-c1ccc(Cl)c(OCc2ccccc2)c1 CHEMBL4290681 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)c(O)c1 CHEMBL4277256 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)c(C(=O)Nc2ccccc2)c1 CHEMBL4294755 IC50 1000.0 nM
Cn1cnc(-c2cc(-c3nn[nH]n3)ccn2)c1-c1ccc(F)c2ccccc12 CHEMBL4284926 IC50 1000.0 nM
Cn1nnc(-c2ccnc(-c3cn(Cc4ccccc4Cl)cn3)c2)n1 CHEMBL4285921 IC50 1000.0 nM
CC(C)(C)C(=O)OCn1nnc(-c2ccnc(-c3cn(Cc4ccccc4Cl)cn3)c2)n1 CHEMBL4286299 IC50 1000.0 nM
CC(=O)OCn1nnc(-c2ccnc(-c3cn(Cc4ccccc4Cl)cn3)c2)n1 CHEMBL4290020 IC50 1000.0 nM
Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2Cc2cccc(Cl)c2)c(OCC2CC2)c1 CHEMBL4290366 IC50 1000.0 nM