CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-c3ccncc3)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4850758 IC50 23.0 nM
CC(C)(C)OC(=O)C[C@@H]1CCN(C(c2ccc(-c3ccncc3)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL5206330 IC50 23.0 nM
CN(c1ccccc1)c1ccc2c(c1)CCC[C@H]2CNc1cnccc1C(=O)O CHEMBL4216044 IC50 35.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(C#N)cn2)c2cc3c(cc2O)OCO3)C1 CHEMBL4875100 IC50 45.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-n3cncn3)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4866032 IC50 56.0 nM
O=C(O)c1ccncc1NCc1ccccc1 CHEMBL3775612 pIC50 63.1 nM
O=C(O)c1ccncc1NCc1ccco1 CHEMBL3775237 IC50 79.0 nM
Cc1nccn1-c1ccc(C(c2cc3c(cc2O)OCO3)N2CC[C@@H](NC(=O)OC(C)(C)C)C2)cc1 CHEMBL4852549 IC50 87.0 nM
Cc1ccsc1CNc1cnccc1C(=O)O CHEMBL3775889 pIC50 100.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cc3c(cc2O)OCO3)c2ccnc3ccccc23)C1 CHEMBL4865890 IC50 100.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cccc(-n3ccnc3)c2)c2cc3c(cc2O)OCO3)C1 CHEMBL4849386 IC50 109.0 nM
Cc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL3786952 IC50 110.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cc3c(cc2O)OCO3)c2ccc(Cl)cc2F)C1 CHEMBL4863496 IC50 111.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cc3c(cc2O)OCO3)c2ccc(F)cc2Cl)C1 CHEMBL4853213 IC50 117.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-c3ccncc3)cn2)c2cc3c(cc2O)OCO3)C1 CHEMBL4870370 IC50 126.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4851604 IC50 135.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(C#N)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4848874 IC50 141.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-c3ccccn3)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4870256 IC50 145.0 nM
O=C(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)C1CC1 CHEMBL4865527 IC50 155.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-c3ccncc3)nc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4867448 IC50 165.0 nM
CCOc1ccc(C(=O)N[C@@H]2CCN(C(c3ccncc3)c3cc4c(cc3O)OCO4)C2)cc1 CHEMBL4852779 IC50 170.0 nM
CC(C)(C)NC(=S)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4853385 IC50 171.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cc3c(cc2O)OCO3)c2ccc(F)cc2F)C1 CHEMBL4867797 IC50 173.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cccc(-c3cccnc3)c2)c2cc3c(cc2O)OCO3)C1 CHEMBL4864457 IC50 184.0 nM
O=C(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)c1ccccc1Cl CHEMBL4869955 IC50 187.0 nM
CC(C)(C)NC(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4879231 IC50 188.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(F)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4847665 IC50 192.0 nM
O=C(NC[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)C1CC1 CHEMBL4857387 IC50 193.0 nM
O=C(Cc1ccccc1)Nc1cnccc1C(=O)O CHEMBL3775431 pIC50 199.53 nM
CN(C)[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4866118 IC50 200.0 nM
O=C(O)c1ccc(O)c2ncccc12 CHEMBL1230640 IC50 200.0 nM
COc1ccc(OC)c(C(c2ccncc2)N2CC[C@@H](NC(=O)OC(C)(C)C)C2)c1O CHEMBL4865163 IC50 212.0 nM
CC(C)C(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4866179 IC50 220.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-c3cccnc3)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4853701 IC50 220.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cccc(-c3ccncc3)c2)c2cc3c(cc2O)OCO3)C1 CHEMBL4850795 IC50 223.0 nM
O=C(CCCc1ccccc1)Nc1cnccc1C(=O)O CHEMBL3774845 pIC50 251.19 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cccc(-c3ccccn3)c2)c2cc3c(cc2O)OCO3)C1 CHEMBL4871665 IC50 285.0 nM
Clc1ccc(N/N=C(\c2ccccc2)c2ccccn2)nc1 CHEMBL1982368 IC50 290.0 nM
O=c1[nH]c(Oc2ccc(Cl)c(O)c2)nc2cnccc12 CHEMBL3770740 pIC50 316.23 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cc3c(cc2O)OCO3)c2ccc(C#N)cc2F)C1 CHEMBL4851379 IC50 330.0 nM
CCOc1ccccc1C(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4876010 IC50 342.0 nM
O=C(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)c1cccc(F)c1 CHEMBL4857330 IC50 351.0 nM
COc1cc(C#N)ccc1C(c1cc2c(cc1O)OCO2)N1CC[C@@H](NC(=O)OC(C)(C)C)C1 CHEMBL4878349 IC50 368.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(C#N)c(F)c2)c2cc3c(cc2O)OCO3)C1 CHEMBL4870942 IC50 382.0 nM
O=c1[nH]c(Oc2cnn(CC3CCCCC3)c2)nc2cnccc12 CHEMBL3771198 pIC50 398.11 nM
O=c1[nH]c(Oc2cnn(Cc3ccccc3)c2)nc2cnccc12 CHEMBL3771180 pIC50 398.11 nM
O=C(CCc1ccccc1)Nc1cnccc1C(=O)O CHEMBL3775245 pIC50 398.11 nM
COc1ccccc1C(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4850241 IC50 399.0 nM
Cc1nn2c(nc(O)c3cccnc32)c1C#N CHEMBL4090908 IC50 410.0 nM
O=C(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)c1ccccc1F CHEMBL4846901 IC50 437.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccc(-n3cccc3)cc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4852615 IC50 444.0 nM
COC(=O)c1ccc(C(c2cc3c(cc2O)OCO3)N2CC[C@@H](NC(=O)OC(C)(C)C)C2)cc1 CHEMBL4878136 IC50 445.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cccc(C#N)c2)c2cc3c(cc2O)OCO3)C1 CHEMBL4865332 IC50 482.0 nM
COC(=O)c1cccc(C(c2cc3c(cc2O)OCO3)N2CC[C@@H](NC(=O)OC(C)(C)C)C2)c1 CHEMBL4855136 IC50 499.0 nM
O=c1[nH]c(Oc2cnn(C3CCCC3)c2)nc2cnccc12 CHEMBL3769724 pIC50 501.19 nM
Cn1nccc1C(c1cc2c(cc1O)OCO2)N1CC[C@@H](NC(=O)OC(C)(C)C)C1 CHEMBL4850962 IC50 509.0 nM
CC(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4878213 IC50 519.0 nM
O=C(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)C1CCCCC1 CHEMBL4869367 IC50 528.0 nM
O=C(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)c1ccccc1 CHEMBL4845871 IC50 536.0 nM
COc1cccc(C(=O)N[C@@H]2CCN(C(c3ccncc3)c3cc4c(cc3O)OCO4)C2)c1 CHEMBL4878151 IC50 546.0 nM
O=C(NC1CC1)[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4848068 IC50 546.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2cnccn2)c2cc3c(cc2O)OCO3)C1 CHEMBL4853657 IC50 552.0 nM
O=S(=O)(N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)C1CC1 CHEMBL4875126 IC50 577.0 nM
O=C(O[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)C1CC1 CHEMBL4877018 IC50 586.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OC(C)(C)O3)C1 CHEMBL4855287 IC50 609.0 nM
CC(C)c1ccc(Oc2nc3cnccc3c(=O)[nH]2)cn1 CHEMBL3769511 pIC50 630.96 nM
COc1cc(O)c(C(c2ccncc2)N2CC[C@@H](NC(=O)OC(C)(C)C)C2)cc1OC CHEMBL4858321 IC50 632.0 nM
CN(C(=O)OC(C)(C)C)[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4851246 IC50 642.0 nM
CC(C)(C)C(=O)N[C@@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1 CHEMBL4866581 IC50 664.0 nM
O=C(N[C@H]1CCN(C(c2ccncc2)c2cc3c(cc2O)OCO3)C1)C1CC1 CHEMBL4875975 IC50 892.0 nM