Cc1nn(-c2nc3ccccc3[nH]2)c(N)c1-c1ccccc1 CHEMBL1398171 IC50 -160000.0 nM
Cc1ccc(-n2ncc3c(N4CCCC4)ncnc32)c(C)c1 CHEMBL1544420 Potency 2.5 nM
COc1cc(C(=O)N2CCN(c3ccccc3)CC2)c([N+](=O)[O-])cc1OC CHEMBL1603504 Potency 3.2 nM
CC1CN(c2ccc(Cl)cc2[N+](=O)[O-])CCN1S(C)(=O)=O CHEMBL1374322 Potency 3.2 nM
Cn1nc(C(F)(F)F)cc1-c1ccc(/C=C(\C#N)C(=O)c2ccccc2)s1 CHEMBL1559324 Potency 4.5 nM
c1ccc(Cn2nnc3cnccc32)cc1 CHEMBL1372339 Potency 4.5 nM
COCC(=O)Nc1ccc2c(c1)OCO2 CHEMBL1325370 Potency 5.0 nM
CC(=O)Nc1cccc(C(=O)/C=C/c2ccco2)c1 CHEMBL1308357 Potency 5.0 nM
Cc1ccccc1OCC(=O)O/N=C(\N)Cc1cccs1 CHEMBL1428808 Potency 5.0 nM
COc1ccc(-c2nnc(Sc3nc4ccccc4o3)c3ccccc23)cc1 CHEMBL1606382 Potency 5.6 nM
O=C(NCc1ccc2c(c1)OCO2)c1ccc(Cl)s1 CHEMBL1300305 Potency 5.6 nM
CCc1ccc(NC2CC(=O)N(CCc3ccc(OC)c(OC)c3)C2=O)cc1 CHEMBL1300426 Potency 5.6 nM
COC(=O)/C(C#N)=C/c1c(-c2ccccc2)nc2n1CCS2 CHEMBL1306372 Potency 5.6 nM
Cc1c(NC(N)=O)c(=O)n(-c2ccccc2)n1C CHEMBL1550801 Potency 5.6 nM
COc1cccc2c(Cl)c(CC=C(Cl)Cl)c(C)nc12 CHEMBL1529649 Potency 5.6 nM
COCCNCCCCSc1ccc(Cl)cc1 CHEMBL1496461 Potency 5.6 nM
C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)C=CC[C@@H]12 CHEMBL1309552 Potency 5.6 nM
COc1cc(NC(S)=NN2CCN(C)CC2)cc(OC)c1OC CHEMBL1449902 Potency 6.3 nM
O=C(NNc1cc(N2CCCC2)nc(N2CCCC2)n1)c1ccc([N+](=O)[O-])cc1 CHEMBL1379448 Potency 6.3 nM
O=C(Nc1ccc2c(c1)CCC2)c1cccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)c1 CHEMBL1520088 Potency 7.1 nM
CCOc1ccc(/C=C2/SC(=S)N(n3c(C)ccc3C)C2=O)cc1 CHEMBL1429549 Potency 7.1 nM
CN(C)S(=O)(=O)Oc1ccccc1C(=O)Nc1ccccc1Cl CHEMBL1571065 Potency 7.9 nM
Cc1cccc(Nc2ncnc3c2cnn3C)c1 CHEMBL1613442 Potency 7.9 nM
NC(=O)c1ccc(NCCCN2CCOCC2)c([N+](=O)[O-])c1 CHEMBL1490098 Potency 8.9 nM
O=C(NCCCCCc1nc2ccccc2[nH]1)c1ccccc1Cl CHEMBL1481013 Potency 8.9 nM
CCC(C)NC(=O)C(Sc1ccccc1)c1ccccc1 CHEMBL1438192 Potency 10.0 nM
O=C(N=Nc1c(O)[nH]c2ccccc12)c1cccc(S(=O)(=O)Nc2ccccc2Cl)c1 CHEMBL1536921 Potency 10.0 nM
CCOC(=O)c1c(C)nn(-c2ncccc2NC(=O)CCC(=O)O)c1C CHEMBL1323319 Potency 10.0 nM
O=C(Nc1ccc(-c2cnco2)cc1)c1ccccc1 CHEMBL1550078 Potency 10.0 nM
CN(C)c1ccc(C=C2C(=O)OC3(CCCC3)OC2=O)cc1 CHEMBL1569153 Potency 10.0 nM
COc1ccc(C(=O)Nc2nc3ccccc3s2)cc1OC CHEMBL1523905 Potency 10.0 nM
CN(C)c1ccc(NC(=O)CN2CCC(O)(c3ccccc3)CC2)cc1 CHEMBL1332029 Potency 11.2 nM
Cc1cccc(C2c3[nH]c4ccccc4c3CCN2C(=O)c2cc3c(nc2O)CCCC3)n1 CHEMBL1368170 Potency 12.6 nM
O=C(Cc1cccc2ccccc12)NCCOc1ccccc1F CHEMBL1443455 Potency 15.8 nM
CN(Cc1cnn(-c2ccc(F)cc2)c1)Cc1nc(Cc2ccccc2)no1 CHEMBL1426405 Potency 15.8 nM
CCc1ccc(NC(=O)CN(c2ccccc2)S(=O)(=O)N(C)C)cc1 CHEMBL1454904 Potency 20.0 nM
N=C(NC1CCCCC1)c1ccc(Cl)cc1 CHEMBL1385656 Potency 20.0 nM
O=C1CCCN1CC1CCN(Cc2nc(CC3CC3)no2)CC1 CHEMBL1321077 Potency 22.4 nM
COC(C(=O)Nc1cccc(F)c1)c1ccccc1 CHEMBL1496496 Potency 22.4 nM
CS(=O)(=O)N1N=C(c2cccs2)CC1c1ccco1 CHEMBL1359903 Potency 25.1 nM
CC(=O)c1ccc(Nc2cc(C)nc3c(C)cccc23)cc1 CHEMBL1491066 Potency 25.1 nM
NNC(=O)c1cc2c(ccc3ccccc32)o1 CHEMBL1338699 Potency 25.1 nM
C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 CHEMBL1506727 Potency 25.1 nM
CC(C)(Cc1ccc(O)cc1)NC(=O)CC(=O)N/N=C/c1ccc([N+](=O)[O-])cc1 CHEMBL3194644 Potency 28.2 nM
COc1ccc(-n2c(C)cc(/C=C3\SC(=S)NC3=O)c2C)cc1 CHEMBL1450827 Potency 28.2 nM
COCCNC(=O)CN1c2ccccc2CC1C CHEMBL1379349 Potency 28.2 nM
O=C(COS(=O)c1ccccc1)Nc1cc(Cl)ccc1N1CCOCC1 CHEMBL1408342 Potency 28.2 nM
O=C(c1ccc(Cl)cc1)c1cc([N+](=O)[O-])ccc1N1CCOCC1 CHEMBL1439227 Potency 31.6 nM
COCCNc1cc(-c2ccccc2)nc2cc(-c3ccc(F)cc3)nn12 CHEMBL1511162 Potency 31.6 nM
CC1CC(C)CN(C(=O)Nc2ccc(Br)cc2)C1 CHEMBL1541984 Potency 35.5 nM
Cc1cc(Cl)ccc1C(=O)C1CCCN(C(=O)c2snnc2C)C1 CHEMBL1486209 Potency 35.5 nM
COc1ccccc1N1CCN(C(CNC(=O)c2ccc3c(c2)OCO3)c2cccnc2)CC1 CHEMBL1492689 Potency 35.5 nM
NC(=NOC(=O)c1ccco1)c1cccc([N+](=O)[O-])c1 CHEMBL1548164 Potency 35.5 nM
CCn1ccnc1CNC(=O)CC1C(=O)NCCN1Cc1ccccc1F CHEMBL1484875 Potency 35.5 nM
O=C(NCc1ccco1)/C(=C\C=C\c1ccccc1)NC(=O)c1ccccc1Br CHEMBL1518812 Potency 39.8 nM
CCNS(=O)(=O)c1ccc2nc(NC(=O)/C=C/c3cc(OC)c(OC)c(OC)c3)sc2c1 CHEMBL1493531 Potency 39.8 nM
Cc1cccc(C(=O)NC2=NCCS2)c1 CHEMBL1446039 Potency 39.8 nM
CC(C)(C)c1ccc(C(=O)Nc2sc3c(c2C(=O)O)CCC3)cc1 CHEMBL1390450 Potency 39.8 nM
Cc1ccc2nc(O)cc(C(=O)OC(C)C)c2c1 CHEMBL1485940 Potency 39.8 nM
O=C(O)c1ccncc1NCc1ccco1 CHEMBL3775237 pIC50 39.81 nM
O=C(O)c1ccncc1NCc1ccccc1 CHEMBL3775612 pIC50 39.81 nM
CC(C)NC(=O)CN1C(=O)c2ccccc2S1(=O)=O CHEMBL1463320 Potency 44.7 nM
Cc1nc(N)nc(N)c1/C=C/C(C)(C)c1ccc(Cl)cc1 CHEMBL1462938 Potency 44.7 nM
CC[n+]1c(C)sc2cc(C)ccc21 CHEMBL1457398 Potency 44.7 nM
CCN1CCCC1CNC(=O)c1ccc(Sc2ccc(F)cc2)c([N+](=O)[O-])c1 CHEMBL1329473 Potency 50.1 nM
Cn1nc(C(=O)Nc2ccc3c(c2)OCCO3)cc1C(=O)O CHEMBL1486129 Potency 50.1 nM
CSc1sc(-c2ccnc(S)n2)c(-c2ccccc2)c1C#N CHEMBL1484325 Potency 50.1 nM
Cc1ccsc1CNc1cnccc1C(=O)O CHEMBL3775889 pIC50 50.12 nM
CNC(=O)NC(=S)NC(=O)c1cccc(Cl)c1 CHEMBL1505345 Potency 56.2 nM
O=S(=O)(NCCCCCNS(=O)(=O)c1ccccc1)c1ccccc1 CHEMBL1455588 Potency 56.2 nM
C=CCC1(Cl)C(=O)C(Cl)=C(N2CCOCC2)C1(OC)OC CHEMBL1447826 Potency 56.2 nM
Nc1cc(N)c(OCC(F)(F)F)cc1OCC(F)(F)F CHEMBL1528757 Potency 63.1 nM
O=C(O)CC1OCC=C2CN3CCC45C6=CC(=O)C(O)=C([N+](=O)[O-])C6=NC4C1C2CC35 CHEMBL1519313 Potency 63.1 nM
CCCCNC(=O)N(c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O)C1CCCC1 CHEMBL1345759 Potency 63.1 nM
CC(=O)Nc1cccc(/C(C)=N/NS(=O)(=O)c2ccc(C)cc2)c1 CHEMBL3211885 Potency 70.8 nM
COc1ccc(-c2cc3ccccc3oc2=O)cc1NC(=O)c1ccc([N+](=O)[O-])o1 CHEMBL1335703 Potency 100.0 nM
CCOC(=O)c1cc2sc(C)cc2n1CC(=O)N1CCOCC1 CHEMBL1452054 Potency 100.0 nM
O=C(O)c1ccnc(-c2cc(C(=O)NCCc3ccccc3)ccn2)c1 CHEMBL2169917 IC50 110.0 nM
COC(=O)c1cnn(-c2ccc(C)c(C)c2)c1-n1cccc1 CHEMBL1386257 Potency 112.2 nM
O=c1[nH]c(Oc2ccc(Cl)c(O)c2)nc2cnccc12 CHEMBL3770740 pIC50 125.89 nM
O=C(CN1CCC(C(=O)O)CC1)Nc1ccccc1Oc1ccccc1 CHEMBL1328954 Potency 125.9 nM
O=C(C(=O)N1CCOCC1)c1c[nH]c2ccccc12 CHEMBL438352 Potency 125.9 nM
CCN(CC)c1ccc(/C=N/Nc2nc(C)cc(O)n2)c(O)c1 CHEMBL3197978 Potency 125.9 nM
CCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 CHEMBL1528629 Potency 125.9 nM
Cc1ccc(S(=O)(=O)c2nc(C)c([N+](=O)[O-])c(C)c2C#N)cc1 CHEMBL211969 Potency 141.3 nM
CCOC(=O)C(C(=O)OCC)c1cc(Br)c2noc3c2c1C(=O)c1ccccc1-3 CHEMBL1331573 Potency 141.3 nM
O=C(Nc1ccc(-c2nc3cc(NC(=O)c4cccs4)ccc3o2)cc1)c1cccs1 CHEMBL1377964 Potency 141.3 nM
Nn1cnnc1N/N=C/c1cc(Br)cc(Br)c1O CHEMBL3195968 Potency 141.3 nM
C=CC(C1=CC(=O)C(OC)=C(OC)C1=O)c1ccccc1 CHEMBL1356393 Potency 141.3 nM
N#Cc1nc(-c2cccs2)oc1N1CCN(c2ccccc2)CC1 CHEMBL1477659 Potency 158.5 nM
O=C(O)CSc1nnc(COc2cccc3ccccc23)n1Cc1ccccc1 CHEMBL1495015 Potency 158.5 nM
Cc1onc(-c2ccccc2Cl)c1C(=O)NC(=S)Nc1ccc(C(C)C)cc1 CHEMBL1534984 Potency 158.5 nM
O=C(c1cc[n+]([O-])cc1)N1CCc2c([nH]c3ccccc23)C1c1ccccc1Cl CHEMBL1414300 Potency 158.5 nM
Cc1cc(=O)oc2c(CN3CC(C)OC(C)C3)c(O)c(Cl)cc12 CHEMBL1485374 Potency 158.5 nM
Cc1cc(Cl)ccc1COc1ccnn1-c1cc(C(=O)O)ccn1 CHEMBL3786952 IC50 160.0 nM
COc1cc(/C=C2/SC(Nc3ccc(O)cc3)=NC2=O)cc(OC)c1O CHEMBL1339850 Potency 177.8 nM
CCCCCC(=O)Nc1nc(C)c(-c2csc(Nc3ccc(Cl)cc3)n2)s1 CHEMBL1403613 Potency 177.8 nM
COc1ccc(-c2[nH]ncc2CN2CCC(C(=O)N3CCOCC3)CC2)c(F)c1 CHEMBL1533574 Potency 177.8 nM
C=C(C)CN(CC)C(=O)c1ccc(OC2CCN(S(=O)(=O)N(C)C)CC2)cc1 CHEMBL1387333 Potency 177.8 nM
CCOc1ccccc1N(CC(=O)NCCOC)C(=O)CCC(=O)Nc1ccccn1 CHEMBL1344376 Potency 177.8 nM
O=C(NNC(=O)c1sccc1-n1cccc1)c1ccc(F)cc1 CHEMBL1546460 Potency 177.8 nM
O=C(O)c1ccnc(C(=O)O)c1 CHEMBL316034 Potency 177.8 nM
NCCNC(=O)c1ccnc(-c2cc(C(=O)O)ccn2)c1 CHEMBL1615036 IC50 180.0 nM
Cc1cc(C)n(CCC(=O)N/N=C/c2c(O)ccc3ccccc23)n1 CHEMBL3190786 Potency 199.5 nM
O=C(CSc1nnnn1C1CCCC1)NCc1cccs1 CHEMBL1587289 Potency 199.5 nM
O=C(O)c1ccc(O)c2ncccc12 CHEMBL1230640 Potency 199.5 nM
NNC(=O)CCC(=O)O CHEMBL2164246 IC50 200.0 nM
OCc1c[nH]cn1 CHEMBL1255967 Potency 223.9 nM
CC(=O)CSc1nnc(-c2cc(C)on2)o1 CHEMBL1589260 Potency 223.9 nM
O=C1SC(c2ccccc2)=N/C1=C/c1ccco1 CHEMBL1576724 Potency 251.2 nM
CC(=O)N1c2ccc(/N=C/c3cc(Br)cc(Br)c3O)cc2CC1C CHEMBL3214071 Potency 251.2 nM
c1cnc2c(c1)ccc1cccnc12 CHEMBL415879 Potency 251.2 nM
CCCCOC(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CC(C)(C)OC3 CHEMBL1609551 Potency 251.2 nM
OCCCNCc1ccc(-c2ccccc2)cc1 CHEMBL1528483 Potency 251.2 nM
COCCn1c(C)cc(C(=O)CN2CCCCC2)c1C CHEMBL1470490 Potency 251.2 nM
CCOC(=O)c1ccc(Cl)c(NC(=O)c2cccnc2)c1 CHEMBL1328160 Potency 251.2 nM
Cc1c(NC(=O)COC(=O)c2ccc(S(=O)(=O)N3CCOCC3)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL1353990 Potency 251.2 nM
O=C(CN1C(=O)/C(=C\c2cccc(Cl)c2)Oc2ccccc21)N1CCN(c2ccccn2)CC1 CHEMBL1523259 Potency 251.2 nM
CCCCN(C)S(=O)(=O)c1ccc(C(=O)/N=c2\sc3cc(NC(C)=O)ccc3n2C)cc1 CHEMBL3189871 Potency 281.8 nM
COc1ccccc1C(=O)N(CCC1CCCN1C)c1nc2ccccc2s1 CHEMBL1583768 Potency 281.8 nM
COc1ccc(COc2cc(-c3cccc(OC)c3)nc3ccc(N)cc23)cc1 CHEMBL1334764 Potency 281.8 nM
Cc1ccc(S(=O)(=O)Nc2ccccn2)cc1[N+](=O)[O-] CHEMBL1391758 Potency 281.8 nM
CCCn1c(O)c(N=NC(=O)c2cccnc2)c2cc(Br)ccc21 CHEMBL1587367 Potency 281.8 nM
Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 CHEMBL1475 Potency 281.8 nM
Clc1ccc(N/N=C(\c2ccccc2)c2ccccn2)nc1 CHEMBL1982368 IC50 290.0 nM
CC(C)N(Cc1ccccc1)C(=S)NC(=O)C1(C)CC1(Cl)Cl CHEMBL1360368 Potency 354.8 nM
COc1ccc(S(=O)(=O)N(C)C)cc1NCC(=O)Nc1cccc(C#N)c1 CHEMBL1529370 Potency 354.8 nM
S=C(NCCc1ccccn1)Nc1cc(Cl)cc(Cl)c1 CHEMBL1487818 Potency 354.8 nM
COc1ccccc1/C=N/Nc1cc(N(C)C)nc(N(C)C)n1 CHEMBL3194941 Potency 354.8 nM
O=C(N/N=C/c1ccc(Br)s1)c1ccc([N+](=O)[O-])cc1 CHEMBL3194060 Potency 354.8 nM
CCc1ccc(/C=C/c2c[nH]c3ccccc23)[n+](CC)c1 CHEMBL1387510 Potency 354.8 nM
O=C(NC(=S)N1CCN(CCO)CC1)C12CC3CC(CC(C3)C1)C2 CHEMBL1534774 Potency 354.8 nM
O=C(O)c1cc(O)c(O)c(O)c1 CHEMBL288114 Potency 354.8 nM
COc1ccc(N2CC(C(=O)Nc3ccc(S(=O)(=O)Nc4nccs4)cc3)CC2=O)cc1 CHEMBL1461739 Potency 354.8 nM
CC1(C)C(=O)N=C2C1=C(O)C(=O)c1ccccc12 CHEMBL580421 Potency 354.8 nM
O=P(O)(O)CP(=O)(O)O CHEMBL180570 Potency 354.8 nM
Cc1[nH]n(-c2ccccc2)c(=O)c1C(c1cccc([N+](=O)[O-])c1)c1c(C)[nH]n(-c2ccccc2)c1=O CHEMBL3145109 Potency 398.1 nM
CC1(C)CNc2cc(N)ccc2S1 CHEMBL1500125 Potency 398.1 nM
O=[N+]([O-])c1ccc(O)c(-c2nn[nH]n2)c1 CHEMBL1495013 Potency 398.1 nM
COc1ccc2c(=O)c(OC)c(-c3ccccc3)oc2c1 CHEMBL1449187 Potency 398.1 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 Potency 398.1 nM
O=C(O)c1ccnc(-c2ccccn2)c1 CHEMBL3621852 pIC50 398.11 nM
CC(C)c1ccc(Oc2nc3cnccc3c(=O)[nH]2)cn1 CHEMBL3769511 pIC50 398.11 nM
O=c1[nH]c(Oc2cnn(C3CCCC3)c2)nc2cnccc12 CHEMBL3769724 pIC50 398.11 nM
O=C(O)CCC(=O)NO CHEMBL51979 IC50 400.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccnc(-c3cc(C(=O)O)ccn3)c2)cc1 CHEMBL3108958 IC50 420.0 nM
O=S(=O)(Nc1ccc(O)c2ncccc12)c1ccccc1F CHEMBL2220622 Potency 434.7 nM
COc1cc([N+](=O)[O-])ccc1N=C(S)Nc1cccc(C(=O)O)c1 CHEMBL1489208 Potency 446.7 nM
CCC(=O)N(Cc1ccco1)Cc1cc2cc3c(cc2nc1O)OCO3 CHEMBL1578854 Potency 446.7 nM
Cc1nc2c(c(=O)n1CCC(C)C)c1nc3ccccc3nc1n2CC1CCCO1 CHEMBL1300028 Potency 446.7 nM
CC(=O)C1=C(c2ccc(Br)cc2)C(=O)c2ccccc2C1=O CHEMBL1567571 Potency 446.7 nM
Cc1ccc(CCCOC(=O)C[N+]2(C)CCCCC2)cc1 CHEMBL1324472 Potency 446.7 nM
Cc1cc(C)cc(NC(=O)COc2ccc3c(C)c(Cc4ccccc4)c(=O)oc3c2)c1 CHEMBL1582626 Potency 446.7 nM
O=C(NCC1COc2ccccc2O1)C1(c2ccccc2)CCCC1 CHEMBL1583334 Potency 446.7 nM
COc1ccc(NC(=O)c2cc3ccc4c5ccccc5[nH]c4c3cc2O)cc1 CHEMBL1372046 Potency 446.7 nM
Cc1ccc(SCc2cc(=O)n(C)[nH]2)cc1 CHEMBL3145143 Potency 446.7 nM
Cc1cc(N/N=C/c2ccc(O)cc2O)nc(-c2ccccc2O)n1 CHEMBL1994963 Potency 446.7 nM
O=C1C(Nc2ccccc2)=C/C(=N/S(=O)(=O)c2cccs2)c2ccccc21 CHEMBL2095095 Potency 446.7 nM
O=c1[nH]c(Oc2cnn(CC3CCCCC3)c2)nc2cnccc12 CHEMBL3771198 pIC50 501.19 nM
O=c1[nH]c(Oc2cnn(Cc3ccccc3)c2)nc2cnccc12 CHEMBL3771180 pIC50 501.19 nM
CCOC(=O)C(CSCC(=O)c1ccc(Cl)cc1Cl)NC(=O)OC(C)(C)C CHEMBL1410592 Potency 501.2 nM
Cn1[nH]c(CSc2ccc(Cl)cc2)cc1=O CHEMBL1643542 Potency 501.2 nM
Cc1cccc2cc(C#N)c(NCCN=C(S)NCCCN3CCOCC3)nc12 CHEMBL1448697 Potency 501.2 nM
Cc1ccccc1Cn1nc(C)c(NC(=O)c2ccccc2)c1C CHEMBL1530264 Potency 501.2 nM
CC1=NC2(O)c3ccccc3C(=O)C2(O)/C1=C(/O)OC(C)C CHEMBL3199015 Potency 501.2 nM
CCCCC(=O)Nc1nn(C)c2nc3c(C)cccc3cc12 CHEMBL1531611 Potency 501.2 nM
COc1cc2c(cc1OC)C(C(C)C)=NC(C)(C)C2 CHEMBL1362942 Potency 501.2 nM
Cc1cc(C)nc(N(C#N)Cc2cccc(Cl)c2)n1 CHEMBL1503141 Potency 501.2 nM
COc1cc2c(cc1NC(=O)COC(=O)c1ccccc1)oc1ccccc12 CHEMBL1328304 Potency 501.2 nM
COc1cc(OC)c(OC)cc1/C=N/Nc1[nH]cnc2c3ccccc3nc1-2 CHEMBL3197580 Potency 501.2 nM
COc1ccc2c(COC(=O)CNC(=O)C34CC5CC(CC(C5)C3)C4)cc(=O)oc2c1 CHEMBL1308488 Potency 501.2 nM
CCOC(=O)C1=C(c2ccc(OC)cc2)C(=O)c2ccccc2C1=O CHEMBL1310221 Potency 501.2 nM
Cc1nc(SCC(=O)Nc2nc3ccccc3s2)c(C#N)c(C)c1C CHEMBL1506503 Potency 501.2 nM
COc1cc(/C=N/Nc2nncn2N)ccc1OCc1c(C)no[n+]1[O-] CHEMBL3189803 Potency 501.2 nM
O=C(O)c1cccc(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)cs2)c1 CHEMBL1567794 Potency 562.3 nM
COc1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCO4)c(OC)c1 CHEMBL1596046 Potency 562.3 nM
COc1cccc2sc(Nc3nnc(-c4ccccc4Cl)o3)nc12 CHEMBL1569543 Potency 562.3 nM
CC1(OC(=O)C2CCCC2)C(=O)C=C2C=C(c3ccsc3)N(CCN3CCOCC3)C=C2C1=O CHEMBL1399283 Potency 562.3 nM
CCN(CC)Cc1c[nH]c2c(C(=O)OC)cccc12 CHEMBL1594354 Potency 562.3 nM
O=c1oc2c(CN3CCOCC3)c(O)c(Cl)cc2c2c1CCCC2 CHEMBL1594989 Potency 562.3 nM
CN1N=C2c3ccccc3CCCC2C1c1ccc(F)cc1 CHEMBL1386152 Potency 562.3 nM
CC1CCc2nc(NC(=O)Cc3cccs3)sc2C1 CHEMBL1611110 Potency 562.3 nM
COc1cccc(-c2cc(C(F)(F)F)c(C#N)c(O)n2)c1 CHEMBL1416151 Potency 562.3 nM
O=[N+]([O-])c1ccc(N2CCCCCC2)c2ncccc12 CHEMBL1505256 Potency 562.3 nM
O=C(O)/C=C/c1ccc(O)c(O)c1 CHEMBL145 Potency 562.3 nM
CCOCCCNC(=O)/C(C#N)=C/c1cc(OC)c(O)c([N+](=O)[O-])c1 CHEMBL1503255 Potency 562.3 nM
CCOC(=O)c1c2ccc(OCC(=O)N/N=C/c3ccc(C)cc3)cc2n2ccccc12 CHEMBL1984130 Potency 562.3 nM
O=C1OCC2OC(O)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2-c2c(O)c(O)c3oc(=O)c4c(c(O)c(O)c5oc(=O)c2c3c54)-c2c1cc(O)c(O)c2O CHEMBL416615 Potency 562.3 nM
NNc1nnc(S)n1N CHEMBL1531579 Potency 562.3 nM
Cc1ccc(O)c(NN=C2C(=O)CC(C)(C)CC2=O)c1 CHEMBL1526167 Potency 562.3 nM
CC1(OC(=O)C2CCCC2)C(=O)C=C2C=C(c3ccsc3)N(CCCCO)C=C2C1=O CHEMBL1378508 Potency 562.3 nM
Oc1cc(-c2ccc(Cl)c(Cl)c2)[nH]n1 CHEMBL566068 Potency 562.3 nM
CCCOc1ccc(N)cc1N CHEMBL1547422 Potency 562.3 nM
COc1cc(C2C3=C(O)CCCC3=Nc3c2c(C)nn3-c2cccc(C)c2)cc(OC)c1O CHEMBL1325946 Potency 562.3 nM
CN1C(=O)CC(Nc2cccc3cccc(N)c23)C1=O CHEMBL1390633 Potency 562.3 nM
NC(=O)c1nn(-c2ccccc2)nc1N CHEMBL1594705 Potency 631.0 nM
CCn1c(=N)c(S(=O)(=O)c2ccc(Cl)cc2)cc2c(=O)n3ccccc3nc21 CHEMBL1340970 Potency 631.0 nM
Cc1cccc(C(=O)NC2C(=O)NNC2c2ccc(Cl)cc2)c1 CHEMBL1409091 Potency 631.0 nM
O=C(NCCCl)C1Cc2c(ccc3ccccc23)O1 CHEMBL1371743 Potency 631.0 nM
CC(=O)N(C1=C(Cl)C(=O)c2ccccc2C1=O)C1CCCCC1 CHEMBL1526855 Potency 631.0 nM
COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC CHEMBL611 Potency 631.0 nM
CCOC(=O)c1c(NC(=O)c2cc3n(n2)C(C(F)(F)F)CC(c2cccs2)N3)sc(C)c1C CHEMBL1490379 Potency 631.0 nM
CCCn1c(=O)c(Cc2ccccc2)c(O)c2ccccc21 CHEMBL1578330 Potency 631.0 nM
CCOC(=O)CCc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL1497991 Potency 631.0 nM
Oc1ccc(/N=C/c2ccc(O)c(O)c2)cc1 CHEMBL1093246 Potency 631.0 nM
CCN(CC)CCCNc1oc(/C=C/c2ccccc2)nc1C#N CHEMBL1576280 Potency 631.0 nM
O=C(CC(c1ccccc1)C1CCCCC1=O)c1ccco1 CHEMBL1359216 Potency 631.0 nM
COc1cc2ccc(=O)oc2cc1O CHEMBL71851 Potency 631.0 nM
Nc1cnccc1C(=O)O CHEMBL1383671 Potency 631.0 nM
O=C1c2cnc3nc(SCc4ccc(Cl)cc4)nn3c2CC2c3ccccc3CCN12 CHEMBL1533997 Potency 631.0 nM
CCCCc1cc(=O)oc2c(CN(CC)CC)c(O)c(Cl)cc12 CHEMBL1377388 Potency 631.0 nM
COC(=O)c1ccc(-c2ccc(C(c3c(C)n[nH]c3O)c3c(C)n[nH]c3O)o2)cc1 CHEMBL1347107 Potency 631.0 nM
Cc1coc2cc3oc(=O)c(CCC(=O)O)c(C)c3cc12 CHEMBL1444197 Potency 631.0 nM
COc1ccc(-c2oc3ncn4nc(Cc5ccccc5)nc4c3c2-c2ccc(OC)cc2)cc1 CHEMBL1344787 Potency 631.0 nM
CCCC1=C(C(=O)OCC)C(c2ccc(OC)c(C)c2OC)C(C#N)=C(N)O1 CHEMBL1567534 Potency 631.0 nM
COc1ccc(CNc2cc(NCCCO)c([N+](=O)[O-])c3nonc23)cc1 CHEMBL1609735 Potency 631.0 nM
Cc1ccc(OCCCC(=O)N2CCOCC2)c(C)c1 CHEMBL1366740 Potency 631.0 nM
CCCc1cc(=O)oc2c(CN3CCCC3)c(O)ccc12 CHEMBL1508743 Potency 631.0 nM
CCCCn1c(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)[nH]c21 CHEMBL1446859 Potency 631.0 nM
COc1ccc(N2C(=O)/C(=C\NNS(=O)(=O)c3ccc(C)c([N+](=O)[O-])c3)c3ccccc3C2=O)cc1OC CHEMBL1471180 Potency 631.0 nM
O=C1c2ccccc2NC2(CCCC2)N1N=C1CCCC1 CHEMBL1472449 Potency 631.0 nM
O=c1ccc2cc(O[C@H]3OC(CO)C(O)C(O)C3O)c(O)cc2o1 CHEMBL1514329 Potency 631.0 nM
Cc1nnc(N/N=C/c2cc(C)n(-c3ccc(F)cc3)c2C)n1N CHEMBL3196994 Potency 631.0 nM
Cc1ccc2[nH]c3c(Cl)ncnc3c2c1 CHEMBL1496526 Potency 631.0 nM
COc1ccc(CCNC(=O)Cn2nnc(-c3ccc(OC)c(OC)c3)n2)cc1OC CHEMBL1326924 Potency 631.0 nM
O=C(CCCCn1c(=O)c2ccccc2n(CC(=O)NC2CCCC2)c1=O)NCc1ccco1 CHEMBL1452182 Potency 631.0 nM
COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)NCCCn4ccnc4)cc3n2)cc1 CHEMBL1602177 Potency 631.0 nM
COc1cc(SC)ccc1C(=O)Nc1ccc(C)cc1C CHEMBL1389695 Potency 631.0 nM
COC(=O)c1ccc(Oc2c(C)oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)cc1 CHEMBL1371596 Potency 707.9 nM
COC(=O)CSc1nnc(-c2ccco2)n1Cc1ccco1 CHEMBL1301477 Potency 707.9 nM
C(=C\c1[nH]ccc2c3ccccc3nc1-2)\c1ccc2c(c1)OCO2 CHEMBL1439668 Potency 707.9 nM
NC(=O)c1ccc(-n2nnnc2SCC(=O)c2ccc(O)c(O)c2)cc1 CHEMBL1439735 Potency 707.9 nM
O=C(CSc1cccc2cccnc12)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1 CHEMBL1382320 Potency 707.9 nM
CCc1cc(=O)oc2c(CN3CCCC3)c(O)c(Cl)cc12 CHEMBL1421867 Potency 707.9 nM
Oc1cc2c(cc1O)C1c3ccc(O)c(O)c3OCC1(O)C2 CHEMBL1479103 Potency 707.9 nM
Cc1cc(C)cc(Oc2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NC2CCS(=O)(=O)C2)c1 CHEMBL1604389 Potency 707.9 nM
COc1ccc(-n2c(C)cc(/C=N/Nc3nnc(C)n3N)c2C)cc1 CHEMBL3198339 Potency 707.9 nM
CCc1nnc(N/N=C/c2cccs2)n1N CHEMBL3192285 Potency 707.9 nM
COc1ccc(OC)c2c1C(=O)C(Cl)=C(Cl)C2=O CHEMBL131037 Potency 707.9 nM
N=c1c(C(=O)NCc2ccco2)cc2c(=O)n3ccccc3nc2n1Cc1ccc(Cl)cc1 CHEMBL1521691 Potency 707.9 nM
O=C1C(Cl)=C(Cl)C(=O)C(Cl)=C1Cl CHEMBL192627 Potency 707.9 nM
Cc1cc(C)c(S(C)(=O)=O)c(Oc2cccc(C(F)(F)F)c2)n1 CHEMBL1543655 Potency 707.9 nM
O=C1CC(c2ccc(F)cc2)Cc2nc(N3CCc4ccccc43)ncc21 CHEMBL1504653 Potency 707.9 nM
CC(=O)c1ccc(NC(S)=Nc2ccc3c[nH]nc3c2)cc1 CHEMBL1347416 Potency 707.9 nM
Cc1cc(=O)oc2cc(N)ccc12 CHEMBL270672 Potency 707.9 nM
CCOC(=O)c1cnn2c(C(F)F)cc(C3CC3)nc12 CHEMBL1307146 Potency 707.9 nM
Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 CHEMBL1387110 Potency 707.9 nM
Cc1ccc(C(=O)OCC(=O)Nc2cccc(Cl)c2C)c(O)c1 CHEMBL1505319 Potency 707.9 nM
N#Cc1c(-c2cccc(Br)c2)cc(-c2cccnc2)nc1N CHEMBL1534306 Potency 707.9 nM
COc1ccc(-n2c(S)nnc2-c2cc(-c3ccccc3)sc2N)cc1 CHEMBL1372357 Potency 707.9 nM
Cc1cc(NC(=O)c2coc(=O)c(Br)c2)ccc1C(C)C CHEMBL1583282 Potency 707.9 nM
CCCCNC(=O)c1cc2c(=O)n3cccc(C)c3nc2n1C CHEMBL1583072 Potency 707.9 nM
CCOC(=O)c1sc2nc(N3CCCC3)c3c(c2c1N)CC(C)(C)OC3 CHEMBL1332486 Potency 707.9 nM
Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NCc3ccccc3)c(N3CCC(C(N)=O)CC3)nc12 CHEMBL1519686 Potency 707.9 nM
N#Cc1c(-c2ccco2)ccn(Cc2cccc(F)c2)c1=O CHEMBL1344651 Potency 707.9 nM
CC(=O)Nc1ccc(N2CCc3c(C)c(C#N)c4nc5ccccc5n4c32)cc1 CHEMBL1452328 Potency 707.9 nM
COc1ccc(-c2cc(N)n(S(=O)(=O)c3ccc(C)cc3)n2)c(OC)c1 CHEMBL1502565 Potency 707.9 nM
Cc1ccccc1NCC(=O)c1ccc(Br)cc1 CHEMBL1461745 Potency 707.9 nM
COc1ccc(-c2cc(=O)c3cc(OC)ccc3o2)cc1 CHEMBL1410006 Potency 707.9 nM
COc1ccccc1/C=N/n1c(N)c(C(=O)NC2CCCCC2)c2nc3ccccc3nc21 CHEMBL1899347 Potency 707.9 nM
CCC(C)NC(=O)c1c(N)n(/N=C/c2cccs2)c2nc3ccccc3nc12 CHEMBL3210678 Potency 707.9 nM
Fc1ccc2c(Cl)c(-c3nnc(-c4cccs4)o3)sc2c1 CHEMBL1480179 Potency 707.9 nM
CCN(CC)C(=O)c1sc2nc(Cc3ccccc3)nc(O)c2c1C CHEMBL1501629 Potency 707.9 nM
Cc1nc2ncnn2c(C)c1CCC(=O)N1CCc2ccccc21 CHEMBL1390824 Potency 707.9 nM
CCn1ccnc1CN(C)Cc1cn(-c2ccc(C)cc2)nc1-c1cccc(C)c1 CHEMBL1352127 Potency 707.9 nM
Cc1cc(C)c2c(c1)[C@@H]1C=CC[C@@H]1[C@H](c1ccc(S(=O)(=O)N3CCOCC3)cc1)N2 CHEMBL1407383 Potency 707.9 nM
CCC(C)N1CN(S(=O)(=O)c2ccc(Cl)cc2)c2nc3ccccc3nc21 CHEMBL1392505 Potency 707.9 nM
O=C(CN1CCCC1)Nc1ccc(-c2nc3cc(NC(=O)CN4CCCC4)ccc3o2)cc1 CHEMBL579045 Potency 707.9 nM
COc1ccc(/C=C/C2=NNC(=O)CC2)cc1 CHEMBL1393809 Potency 707.9 nM
CC(c1nccs1)N(C)c1nc2nonc2nc1N(C)C CHEMBL1394000 Potency 707.9 nM
Cc1ccc(C)c(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1 CHEMBL1326748 Potency 707.9 nM
CC(C)(C)OC(=O)NCCC(=O)Oc1ccc2ccc(=O)oc2c1 CHEMBL1378073 Potency 707.9 nM
O=C(O)C[C@@H]1C(=O)O[C@@H]2C(COC(=O)c3cc(O)c(O)c(O)c3)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H]2OC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1391063 Potency 707.9 nM
COc1cccc(/C=N/n2c(N)c(S(=O)(=O)c3cccs3)c3nc4ccccc4nc32)c1 CHEMBL3211217 Potency 707.9 nM
OC1=C(/C=N/c2ccc(O)cc2)CCCC1 CHEMBL3198838 Potency 707.9 nM
Cc1n[nH]c(O)c1C(c1c(C)n[nH]c1O)c1cn(Cc2ccccc2Cl)c2ccccc12 CHEMBL1445617 Potency 707.9 nM
Cc1ccc(Cn2c(SC(C)C(N)=O)nc3ccccc3c2=O)cc1 CHEMBL1367502 Potency 707.9 nM
Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1 CHEMBL1445191 Potency 707.9 nM
CC(C)(C)OC(=O)N1CCC(c2cc(O)[nH]n2)CC1 CHEMBL1524399 Potency 707.9 nM
Cc1[nH]c2ccccc2c1C(O)CN1CCN(c2cccc(C(F)(F)F)c2)CC1 CHEMBL1327137 Potency 707.9 nM
CN(C)c1cccc(C(=O)OC(C(=O)Nc2ccc(Cl)cc2C(F)(F)F)c2ccccc2)c1 CHEMBL1601659 Potency 707.9 nM
O=c1cc(-c2ccc(O)cc2)oc2cc(O)ccc12 CHEMBL294878 Potency 794.3 nM
CO[C@H]1C=CO[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(C=NN5CCN(C)CC5)c(O)c4c3C2=O)NC(=O)C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C CHEMBL1604283 Potency 794.3 nM
COc1cc(OC)c(OC)cc1CN1CCN(Cc2cccn2C)CC1 CHEMBL1460014 Potency 794.3 nM
CCOC(=O)c1cc2cc3ccccc3cc2[nH]1 CHEMBL1491264 Potency 794.3 nM
O=C(O)c1cc2c(s1)-c1ccccc1CC2 CHEMBL1421818 Potency 794.3 nM
NC(=O)COc1ccccc1C(=O)O CHEMBL1577740 Potency 794.3 nM
Cc1nn(-c2ccccc2)c2nc(N)c(C#N)c(-c3ccc(F)cc3)c12 CHEMBL1422096 Potency 794.3 nM
COc1ccc(C(c2c(C)[nH]n(-c3ccccc3)c2=O)c2c(C)[nH]n(-c3ccccc3)c2=O)cc1OC CHEMBL3145089 Potency 794.3 nM
Cc1cc(N2CCCC2=O)ccc1S(=O)(=O)N1CCOCC1 CHEMBL1409880 Potency 794.3 nM
COCCN(CCOC)c1nc(N)c2c(N)nc3c(c2c1C#N)CC(=O)N3Cc1ccc(Cl)cc1 CHEMBL1358943 Potency 794.3 nM
COCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cccc(C)c3nc21 CHEMBL1339597 Potency 794.3 nM
CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3sccc3C(N)=O)cc2)CC(C)O1 CHEMBL1575466 Potency 794.3 nM
Cc1ccc(NC(=O)c2ccc(NCC3CCCO3)c([N+](=O)[O-])c2)cc1Cl CHEMBL1517176 Potency 794.3 nM
COc1ccc(CNC(=O)c2c(O)c3cccc4c3n(c2=O)CCC4)cc1 CHEMBL1498314 Potency 794.3 nM
O=C(CSCc1cc(O)n[nH]1)Nc1ccc(F)cc1 CHEMBL1603885 Potency 794.3 nM
CN1N=C(C(C)(C)C)CC1=O CHEMBL1566134 Potency 794.3 nM
Cc1cccn2c(=O)c3cc(C#N)/c(=N\C(=O)c4cccs4)n(CC(C)C)c3nc12 CHEMBL3193659 Potency 794.3 nM
CCCC(=O)Nc1ccc(-c2nc3cc(C)c(C)cc3o2)cc1 CHEMBL1411317 Potency 794.3 nM
CCc1c(C)c2cc(Cl)c(O)c(CN(CC)CC)c2oc1=O CHEMBL1611681 Potency 794.3 nM
COc1ccc2[nH]c3c4c(ccc3c2c1)C(=O)C=CC4=O CHEMBL1607313 Potency 794.3 nM
C=CCN1C(=O)NC(=O)/C(=C(/CC)Nc2ccc(N(CC)CC)cc2)C1=O CHEMBL1337193 Potency 794.3 nM
CCOc1ccc2nc(NC(=O)COc3ccc(N(C)S(=O)(=O)c4ccc(C)cc4)cc3)sc2c1 CHEMBL1599877 Potency 794.3 nM
CSc1nnc(C)c(/C=C/NOCc2ccc(Cl)cc2)n1 CHEMBL1558378 Potency 794.3 nM
CCCn1c(=O)c2c(C(F)(F)F)cc(-c3ccco3)nc2n(CCC)c1=O CHEMBL1501900 Potency 794.3 nM
Cc1nn(-c2ccccn2)c2c1-c1nc(N3CCOCC3)ncc1CC2 CHEMBL1424266 Potency 794.3 nM
CCOC(=O)c1c(-c2ccc(C)cc2)csc1NC(=O)CCSc1nnc2ccccn12 CHEMBL1480042 Potency 794.3 nM
O=C(c1ccc2[nH]cnc2c1)N1CCc2ccccc2C1 CHEMBL1403381 Potency 794.3 nM
CCN(CC)c1ccc(/N=C/c2c(C)[nH]c3ccccc23)cc1 CHEMBL3192970 Potency 794.3 nM
CCCC(=O)Nc1ccc(-c2nc3cc(C)c(C)cc3o2)c(O)c1 CHEMBL1450032 Potency 794.3 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 Potency 794.3 nM
COc1ccc(S(=O)(=O)N(CC(=O)O)c2ccccn2)cc1 CHEMBL1570577 Potency 794.3 nM
O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1392315 Potency 794.3 nM
COc1ccc(-c2oc3ncn4nc(COc5ccccc5)nc4c3c2-c2ccc(OC)cc2)cc1 CHEMBL1570532 Potency 794.3 nM
CCCCCCc1cc2cc(C(=O)OCC)c(=O)oc2cc1O CHEMBL1510940 Potency 794.3 nM
CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCN(C)C)C3c3ccccc3F)ccc2O1 CHEMBL1353116 Potency 794.3 nM
Cc1cc(NC(=O)CSc2nnc(-c3cccs3)n2N)no1 CHEMBL1589692 Potency 794.3 nM
COc1ccc(-c2nc(C#N)c(NCCc3ccccc3)o2)cc1 CHEMBL1449759 Potency 794.3 nM
O=C(CSCc1ccc(Cl)cc1)Nc1ccc(-c2nnc(-c3ccccc3)o2)cc1 CHEMBL1522925 Potency 794.3 nM
O=C([O-])CSc1cccc2cccnc12 CHEMBL1548018 Potency 794.3 nM
COC(=O)N1[C@H](C)C=C[C@]1(Cc1ccccc1)C(=O)NCCCNc1ncc(C(F)(F)F)cc1Cl CHEMBL1338601 Potency 794.3 nM
CN1C(=O)SC(Nc2ccccc2C(=O)O)C1=O CHEMBL1372512 Potency 794.3 nM
COc1ccc2cc(CN(CC3COCCO3)S(=O)(=O)c3ccc(Cl)cc3)c(O)nc2c1 CHEMBL1523338 Potency 794.3 nM
CCCCn1c(=O)[nH]c(=O)c2c1nc(-c1ccc(OCCC)c(OCC)c1)n2CCOC CHEMBL1601050 Potency 794.3 nM
Oc1nc(/C=C/c2ccccc2OC(F)F)nc2c1cnn2-c1ccccc1 CHEMBL1389496 Potency 794.3 nM
Cc1nc(NC(=S)NC(=O)c2cncc(Br)c2)ccc1Br CHEMBL1430969 Potency 794.3 nM
CCOC(=O)CSc1nc(N)nc(C)c1Cl CHEMBL1530616 Potency 794.3 nM
N#CC1=C([C-](C#N)C#N)NC(O)(c2ccccc2)C([n+]2ccccc2)C1c1cccs1 CHEMBL1470198 Potency 794.3 nM
COC(=O)c1c(-n2cnnn2)sc(C)c1C CHEMBL1405666 Potency 794.3 nM
COC(=O)c1c(C)nc2nonc2c1N CHEMBL1601697 Potency 794.3 nM
O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)NC1CCCCC1 CHEMBL1508629 Potency 794.3 nM
O=C(O)c1cccnc1C(=O)O CHEMBL286204 Potency 891.3 nM
Cc1c(C#N)sc2nc(-c3ccccc3)nc(N3CCCC3)c12 CHEMBL1555895 Potency 891.3 nM
O=C(O)CCc1nn2c3ccccc3n(CC(=O)O)c2nc1=O CHEMBL1410938 Potency 891.3 nM
c1ccc(CNc2c3c(nc4ccccc24)CCC3)cc1 CHEMBL1439383 Potency 891.3 nM
CN(C)Cc1cc(O)c(CN(C)C)cc1O CHEMBL1565767 Potency 891.3 nM
CN1CCN(c2nc(-c3ccc(N(C)C)cc3)nc3ccccc23)CC1 CHEMBL1320607 Potency 891.3 nM
N#Cc1cc2c(ccc3ccccc32)oc1=O CHEMBL1565827 Potency 891.3 nM
O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12 CHEMBL8260 Potency 891.3 nM
O=[N+]([O-])c1ccccc1C1Nc2cccc3cccc(c23)N1 CHEMBL1382559 Potency 891.3 nM
C=CCNC(=S)N/N=C/c1ccc(-c2cc(Cl)ccc2Cl)o1 CHEMBL3190572 Potency 891.3 nM
Cc1cc(C)cc(N(C(C)C(=O)NCCC2=CCCCC2)S(C)(=O)=O)c1 CHEMBL1575874 Potency 891.3 nM
CC(=O)c1ccc(N2CCN(C(=O)C3(S(=O)(=O)c4ccc(Cl)cc4)CC3)CC2)cc1 CHEMBL1328983 Potency 891.3 nM
Cc1ccc(N2N=C(c3ccc(F)cc3)CC2c2ccco2)cc1 CHEMBL1527772 Potency 891.3 nM
O=C1C(SCCO)=C(SCCO)C(=O)c2ccccc21 CHEMBL429095 Potency 891.3 nM
Cc1cc(C)nc(SCc2cn3cc(Cl)ccc3n2)n1 CHEMBL1306441 Potency 891.3 nM
CC1CC(C(F)F)n2nc(C(=O)Nc3sc4c(c3C#N)CCC(C(C)(C)C)C4)nc2N1 CHEMBL1533707 Potency 891.3 nM
C=C[C@@H](C1=CC(=O)C(OC)=C(OC)C1=O)c1ccccc1 CHEMBL1591258 Potency 891.3 nM
COc1ccc(Cc2nc(-c3ccncc3)no2)cc1 CHEMBL1383800 Potency 891.3 nM
CN(C)c1cc(N/N=C/c2ccc(Cl)cc2)nc(N(C)C)n1 CHEMBL3189845 Potency 891.3 nM
CN1CCN(CCC(=O)N/N=C/c2cc([N+](=O)[O-])ccc2O)CC1 CHEMBL3213002 Potency 891.3 nM
CCCCn1c(=O)[nH]c(=O)c2c1nc(-c1ccc(OCCC)c(OCC)c1)n2C CHEMBL1579803 Potency 891.3 nM
CCN(CC)C(=O)C1CCN(S(=O)(=O)c2ccc3oc4ccccc4c3c2)CC1 CHEMBL1375365 Potency 891.3 nM
Nc1nc2c(c3c1c(=O)oc1ccccc13)CCCCC2 CHEMBL1558422 Potency 891.3 nM
CCOC(=O)c1c(C)nc(C(Cl)(Cl)Cl)nc1N CHEMBL1363849 Potency 891.3 nM
Cc1cc(-c2ccccc2)c2nncn2n1 CHEMBL1507584 Potency 891.3 nM
COc1cc(NC(=O)COC(=O)/C=C/c2ccc(OC)c(OC)c2)cc(OC)c1 CHEMBL1549285 Potency 891.3 nM
O=C1CCC(/C=C/c2ccccc2)=NN1Cc1ccccc1 CHEMBL1549906 Potency 891.3 nM
N=c1c2c(-c3ccccc3)c(-c3ccccc3)oc2ncn1CCN1CCOCC1 CHEMBL1589137 Potency 891.3 nM
COc1ccc(N(CC(=O)N/N=C/c2cc3ccc(OC)cc3nc2Cl)S(=O)(=O)c2ccccc2)cc1 CHEMBL3209148 Potency 891.3 nM
CC(C(=O)O)N1C(=O)/C(=C/C=C/c2ccco2)SC1=S CHEMBL255881 Potency 891.3 nM
CC(=O)N1CCN(c2ccc(NC(=O)c3ccc(OCc4ccccc4)cc3)cc2)CC1 CHEMBL1309885 Potency 891.3 nM
NCCOB(c1ccccc1)c1ccccc1 CHEMBL169233 Potency 891.3 nM
CCCC(c1nnnn1Cc1ccc2c(c1)OCO2)N1CCC(C(N)=O)CC1 CHEMBL1563756 Potency 891.3 nM
COc1ccc(C(=O)c2coc3c2C(=O)C(=O)c2ccccc2-3)cc1 CHEMBL1469698 Potency 891.3 nM
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 CHEMBL1256472 Potency 891.3 nM
O=c1c2ccccc2nc2n1C(CSCc1cccc(C(F)(F)F)c1)CS2 CHEMBL1467940 Potency 891.3 nM
Cc1ccc(C2=Nc3c(c(=O)[nH]c(=O)n3-c3ccc(F)cc3)C(C(F)(F)F)(C(F)(F)F)N2)cc1 CHEMBL1388753 Potency 891.3 nM
C=CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)c1C#N CHEMBL1562914 Potency 891.3 nM
COC(=O)c1cc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)n2n1 CHEMBL1496310 Potency 891.3 nM
O=C1CN(C(=O)c2ccc(Cl)c(S(=O)(=O)N3CCc4ccccc43)c2)c2ccccc2N1 CHEMBL1366576 Potency 891.3 nM
Cc1nn(-c2nc3ccccc3[nH]2)c(O)c1-c1ccccc1 CHEMBL1933775 IC50 900.0 nM
CN(C)CCCNC(=O)c1ccc(-c2cc(O)c3ncccc3c2)cc1 CHEMBL1398529 IC50 920.0 nM
CC(Nc1c(C(=O)O)ccnc1C(=O)O)c1ccccc1 CHEMBL5429223 IC50 990.0 nM