NC1(c2ccc(-c3nc(N4CC[C@@H]4C(F)(F)F)nc4c3CCC4(F)F)cc2)COC1 CHEMBL5402865 IC50 0.5 nM
C[C@H]1[C@H](O)CN1c1nc(N2C[C@@H]3[C@@H](CC(=O)O)[C@@H]3C2)cc(C(F)(F)F)c1C#N CHEMBL4754053 IC50 1.0 nM
CSc1ccccc1Nc1nc(N2CCC3(CNC3)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2063924 IC50 2.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CNC3)c2)cc(C(F)(F)F)c1C#N CHEMBL5393859 IC50 2.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CN(C)C3)c2)cc(C(F)(F)F)n1 CHEMBL5410032 IC50 3.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CCNCC3)c2)cc(C(F)(F)F)c1C#N CHEMBL5432883 IC50 4.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CNC3)c2)cc(C(F)(F)F)n1 CHEMBL5394335 IC50 4.0 nM
CCN1CCC(n2cc(-c3cc(C(F)(F)F)c(C#N)c(N4CC[C@@H]4C)n3)cn2)CC1 CHEMBL5397861 IC50 4.0 nM
C[C@H]1CCN1c1nc(N2C[C@@H]3[C@@H](CC(=O)O)[C@@H]3C2)cc(C(F)(F)F)n1 CHEMBL4549658 Ki 4.53 nM
C[C@H]1CCN1c1nc(-c2cnn(CCO)c2)cc(C(F)(F)F)c1C#N CHEMBL5426875 IC50 5.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CCN(C)CC3)c2)cc(C(F)(F)F)c1C#N CHEMBL5420041 IC50 6.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CCN(C(=O)CN)CC3)c2)cc(C(F)(F)F)c1C#N CHEMBL5396410 IC50 6.0 nM
C[C@H]1CCN1c1nc(-c2cnn(CC(=O)N3CCN(C)CC3)c2)cc(C(F)(F)F)c1C#N CHEMBL5426396 IC50 6.0 nM
COCCNc1ncnc2c(Nc3ccccc3SC)nc(N3CCNCC3)nc12 CHEMBL2017244 IC50 7.0 nM
C[C@H]1CCN1c1nc(-c2cnn(CC(=O)N3C[C@H](O)[C@@H](O)C3)c2)cc(C(F)(F)F)c1C#N CHEMBL5430716 IC50 7.0 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(N)ncnc12 CHEMBL2017248 IC50 7.1 nM
CSc1ccccc1Nc1nc(N2CC3(CNC3)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2017253 IC50 8.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CCNCC3)c2)cc(C(F)(F)F)n1 CHEMBL5414802 IC50 8.0 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCc3ccccn3)ncnc12 CHEMBL2017247 IC50 9.8 nM
CSc1ccccc1Nc1nc(N2CCC(CN)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017251 IC50 10.0 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017214 IC50 12.0 nM
C[C@H]1[C@H](O)CN1c1nc(N2C[C@@H]3[C@@H](CC(=O)O)[C@@H]3C2)cc(C(F)(F)F)n1 CHEMBL4782925 IC50 14.0 nM
C[C@H]1CCN1c1nc(-c2cn[nH]c2)cc(C(F)(F)F)c1C#N CHEMBL5438733 IC50 14.0 nM
CSc1ccccc1Nc1nc(N2CCC3(CCNCC3)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2063925 IC50 15.0 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCc3nccs3)ncnc12 CHEMBL2017246 IC50 16.0 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CCC3)ncnc12 CHEMBL2017242 IC50 18.0 nM
CSc1ccccc1Nc1nc(N2CCC[C@@H](N)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2017249 IC50 18.0 nM
C[C@H]1CCN1c1nc(-c2cnn(CC(=O)N3CCNCC3)c2)cc(C(F)(F)F)n1 CHEMBL5441069 IC50 20.0 nM
C[C@H]1CCN1c1nc(N2C[C@H]3CC[C@H](C(=O)O)[C@H]3C2)cc(C(F)(F)F)c1C#N CHEMBL5427050 IC50 21.89 nM
C[C@H]1CCN1c1nc(-c2cnn(CCN(C)C)c2)cc(C(F)(F)F)c1C#N CHEMBL5439376 IC50 22.0 nM
CSc1nn(-c2ccc(F)cc2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809168 IC50 23.0 nM
CSc1ccccc1Nc1nc(N2CCC[C@H](N)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2017250 IC50 23.0 nM
O=C(O)CC[C@H]1CCN(c2nc(N3CC[C@@H]3C(F)(F)F)nc3c2CCC3(F)F)C1 CHEMBL5402452 IC50 25.92 nM
CSc1ccccc1Nc1nc(N2CCC(N3CCNCC3)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2063927 IC50 28.0 nM
CC(=O)N1CCC(n2cc(-c3cc(C(F)(F)F)c(C#N)c(N4CC[C@@H]4C)n3)cn2)CC1 CHEMBL5434254 IC50 29.0 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCc3cccs3)ncnc12 CHEMBL2017245 IC50 30.0 nM
CSc1ccccc1Nc1nc(N2CC(CN)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2017252 IC50 30.0 nM
CSc1ccccc1Nc1nc(N2CCC(N3CCN(C)CC3)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2063929 IC50 30.0 nM
C[C@H]1CCN1c1nc(-c2cnn(C3CCOCC3)c2)cc(C(F)(F)F)c1C#N CHEMBL5435927 IC50 33.0 nM
CSc1nn(-c2cccc(C)c2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809169 IC50 34.0 nM
C[C@H]1CCN1c1nc(-c2cnn(CC(=O)N3C[C@@H](O)[C@H](O)C3)c2)cc(C(F)(F)F)c1C#N CHEMBL5423320 IC50 34.0 nM
C[C@H]1CCN1c1nc(N2C[C@H]3CC[C@H](C(=O)O)[C@H]3C2)c2c(n1)C(F)(F)CC2 CHEMBL5401360 IC50 34.72 nM
C[C@H]1CCN1c1nc(N2CC[C@H](CCC(=O)O)C2)c2c(n1)C(F)(F)CC2 CHEMBL5408214 IC50 35.12 nM
C[C@H]1CCN1c1nc(-c2cnn(CC(=O)NCCO)c2)cc(C(F)(F)F)c1C#N CHEMBL5399255 IC50 38.0 nM
C[C@H]1CCN1c1nc(-c2cnn(CC(=O)N(CCO)CCO)c2)cc(C(F)(F)F)c1C#N CHEMBL5405686 IC50 39.0 nM
CSc1nn(-c2ccc(C)cc2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809170 IC50 40.0 nM
CSc1ccccc1Nc1nc(N2CCNC(C)(C)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2063916 IC50 40.0 nM
OC[C@H]1CCN1c1nc(-c2cnn(C3CNC3)c2)cc(C(F)(F)F)n1 CHEMBL5410394 IC50 40.0 nM
CSc1nn(-c2cccc(F)c2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809167 IC50 42.0 nM
CSc1ccccc1Nc1nc(N2CCC3(CCNC3)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2063923 IC50 43.0 nM
CSc1ccccc1Nc1nc(N2CCN(C3CCNCC3)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2063926 IC50 48.0 nM
C[C@H]1CCN1c1nc(N2CC[C@H](CC(=O)O)C2)c2c(n1)C(F)(F)CC2 CHEMBL5434549 IC50 49.03 nM
CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCCC3CC3)ncnc12 CHEMBL2017243 IC50 50.0 nM
CSc1ccccc1Nc1nc(N2CCC(C3CCNCC3)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2063928 IC50 50.0 nM
C[C@H]1CCN1c1nc(N2CC[C@H](OCC(=O)O)C2)c2c(n1)C(F)(F)CC2 CHEMBL5411144 IC50 53.94 nM
CSc1ccccc1Nc1nc(N2CCNC[C@H]2C)nc2c(NCC3CC3)ncnc12 CHEMBL2063914 IC50 58.0 nM
Cc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCc3nccs3)ncnc12 CHEMBL2017235 IC50 60.0 nM
CSc1ccccc1Nc1nc(N(C)CC2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2063917 IC50 66.0 nM
Cc1ccccc1Nc1nc(N2CCC(CN)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017239 IC50 70.0 nM
CSc1ccccc1Nc1nc(N2CCNC(C)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2063913 IC50 70.0 nM
CSc1nn(-c2ccccc2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809152 IC50 80.0 nM
COc1ccc(-n2nc(SC)c3ccc(C4=CCNCC4)cc32)cc1 CHEMBL1809171 IC50 87.0 nM
C[C@H]1CCN1c1nc(N2CC[C@H](CCC(=O)O)C2)c2c(n1)C(F)(F)CCC2 CHEMBL5407523 IC50 89.55 nM
OC[C@H]1CCN1c1nc(-c2cnn(C3CCNCC3)c2)cc(C(F)(F)F)n1 CHEMBL5395414 IC50 98.0 nM
COc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017212 IC50 100.0 nM
C[C@H]1CCN1c1nc(N2CC(CC(=O)O)C(F)(F)C2)cc(C(F)(F)F)c1C#N CHEMBL5419385 IC50 108.05 nM
C[C@H]1CCN1c1nc(N2CCC3(CC3C(=O)O)C2)cc(C(F)(F)F)c1C#N CHEMBL5408159 IC50 108.32 nM
CSc1ccccc1Nc1nc(N2CCN(C)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017256 IC50 110.0 nM
CSc1ccccc1Nc1nc(N2C[C@@H](C)N[C@@H](C)C2)nc2c(NCC3CC3)ncnc12 CHEMBL2063915 IC50 110.0 nM
CCc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017220 IC50 130.0 nM
CNCCN(C)c1nc(Nc2ccccc2SC)c2ncnc(NCC3CC3)c2n1 CHEMBL2017254 IC50 130.0 nM
C[C@H]1CCN1c1nc(N2C[C@@H](CC(=O)O)[C@H](O)C2)cc(C(F)(F)F)c1C#N CHEMBL5431020 IC50 137.7 nM
CSc1ccccc1Nc1nc(N2CCC(CN(C)C)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017255 IC50 140.0 nM
C[C@H]1[C@H](O)CN1c1nc(N2C[C@@H]3[C@@H](CO)[C@@H]3C2)cc(C(F)(F)F)c1C#N CHEMBL4760155 IC50 140.0 nM
CSc1nn(-c2ccc(N)cc2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809173 IC50 160.0 nM
Cc1nn(-c2ccccc2)c2cc(NC(=O)c3ccc4nc[nH]c4c3)ccc12 CHEMBL3666113 IC50 160.0 nM
Brc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017225 IC50 170.0 nM
CCOc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017213 IC50 200.0 nM
Cc1ccccc1Nc1nc(N2CCC(N)CC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017240 IC50 200.0 nM
Cc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017209 IC50 210.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3CNC3)ccc12 CHEMBL1809159 IC50 220.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)c3cccnc3)ccc12 CHEMBL3666076 IC50 230.0 nM
CSc1nn(-c2ccccc2)c2cc(/C=C/C3CCNCC3)ccc12 CHEMBL3666167 IC50 230.0 nM
CSc1nn(-c2ccccc2)c2c(OCC3CCNCC3)cccc12 CHEMBL1809166 IC50 240.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3CCCN3)ccc12 CHEMBL3666075 IC50 260.0 nM
C[C@H]1CCN1c1nc(N2CCC3(CC(C(=O)O)C3)C2)cc(C(F)(F)F)c1C#N CHEMBL5430902 IC50 280.15 nM
C#CCNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 CHEMBL2017232 IC50 300.0 nM
Cc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCc3cccs3)ncnc12 CHEMBL2017234 IC50 300.0 nM
Cc1ccccc1Nc1nc(N2CCCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017236 IC50 300.0 nM
CSc1ccccc1Nc1nc(N2CCC[C@H]3CNC[C@H]32)nc2c(NCC3CC3)ncnc12 CHEMBL2063919 IC50 300.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCN(c4ccncc4)CC3)ccc12 CHEMBL3666090 IC50 300.0 nM
CCc1nn(-c2ccccc2)c2nc(-c3ccc(N4CC(C)NC(C)C4)cc3)cc(OC)c12 CHEMBL3639650 IC50 300.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(N)CCNCC3)ccc12 CHEMBL3666174 IC50 300.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3CCCNC3)ccc12 CHEMBL1809157 IC50 310.0 nM
COc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)CC3)ccc12 CHEMBL3666122 IC50 310.0 nM
C[C@]1(O)CCN(c2nc(N3C[C@H](O)[C@@H](O)C3)cc(C(F)(F)F)c2C#N)C1 CHEMBL4070442 pIC50 316.23 nM
CSc1nn(-c2ccccc2)c2cc(C3CCNCC3)ccc12 CHEMBL1809150 IC50 330.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3CCNCC3)ccc12 CHEMBL1236391 IC50 330.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)CCN3CCNCC3)ccc12 CHEMBL1809161 IC50 380.0 nM
c1ccc(C2CC2)c(Nc2nc(N3CCNCC3)nc3c(NCC4CC4)ncnc23)c1 CHEMBL2017222 IC50 380.0 nM
CSc1nn(-c2cccc(C)c2)c2cc(N3CCN(C4CCNCC4)CC3)ccc12 CHEMBL3666156 IC50 380.0 nM
COc1nn(-c2ccccc2)c2cc(N3CC(N4CCNCC4)C3)ccc12 CHEMBL3666120 IC50 390.0 nM
C[C@H]1[C@H](O)CN1c1nc(N2C[C@@H]3[C@H](C2)[C@H]3C(=O)O)cc(C(F)(F)F)c1C#N CHEMBL4793621 IC50 390.0 nM
CNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 CHEMBL2017208 IC50 400.0 nM
CCCNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 CHEMBL2017228 IC50 400.0 nM
Cc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCc3ccccc3)ncnc12 CHEMBL2017233 IC50 400.0 nM
Cc1nn(-c2ccccc2)c2cc(N3CCNC(C)C3)ccc12 CHEMBL3666118 IC50 400.0 nM
C[C@]1(O)CCN(c2nc(N3C[C@@H](O)[C@@H](O)C3)cc(C(F)(F)F)c2C#N)C1 CHEMBL4762437 IC50 410.0 nM
CSc1nn(-c2ccccc2)c2cc(NCC3CCNCC3)ccc12 CHEMBL3666153 IC50 420.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCN(C(=O)C4CCCCN4)CC3)ccc12 CHEMBL3666095 IC50 430.0 nM
CSc1nn(-c2ccccc2)c2cc(OCC3CCNCC3)ccc12 CHEMBL1809156 IC50 440.0 nM
CSc1ccccc1Nc1nc(N2CCC[C@@H]3CNC[C@@H]32)nc2c(NCC3CC3)ncnc12 CHEMBL2063918 IC50 440.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)NC3CCNC3)ccc12 CHEMBL3666070 IC50 450.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)C3=O)ccc12 CHEMBL3666086 IC50 460.0 nM
C[C@H]1[C@H](O)CN1c1nc(N2C[C@@H](O)[C@@H](O)C2)cc(C(F)(F)F)c1C#N CHEMBL4798024 IC50 470.0 nM
CSc1nn(-c2ccc([N+](=O)[O-])cc2)c2cc(C3=CCNCC3)ccc12 CHEMBL1809172 IC50 480.0 nM
CSc1nn(-c2ccccc2)c2cc(C3=CCN(C(=O)CCN)CC3)ccc12 CHEMBL3666170 IC50 480.0 nM
Clc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017224 IC50 540.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCCNCC3)ccc12 CHEMBL3666074 IC50 540.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCNCC3)ccc12 CHEMBL1809151 IC50 560.0 nM
CCc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNCC4)CC3)ccc12 CHEMBL1809178 IC50 560.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CC(N4CCNCC4)C3)ccc12 CHEMBL3666077 IC50 560.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCC(N4CCNCC4)C3)ccc12 CHEMBL3666081 IC50 560.0 nM
CCc1nn(-c2ccccc2)c2cc(N3CCNCC3)ccc12 CHEMBL1809177 IC50 570.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3CCNC3)ccc12 CHEMBL1809158 IC50 590.0 nM
CCc1nn(-c2ccccc2)c2cc(N3CC4CNCC4C3)ccc12 CHEMBL1809182 IC50 590.0 nM
Cc1nn(-c2ccccc2)c2nc(-c3ccc(N4CCNCC4)cc3)cc(CO)c12 CHEMBL3666143 IC50 600.0 nM
CSc1nn(-c2ccccc2)c2cc(NCCC3CCNCC3)ccc12 CHEMBL3666180 IC50 600.0 nM
CSc1nn(-c2ccccc2)c2cc(/C=C/C3CCCN3)ccc12 CHEMBL3666186 IC50 610.0 nM
CCOc1cc(-c2ccc(N3CCN(C)CC3)cc2)nc2c1c(CC)nn2-c1ccccc1 CHEMBL3666147 IC50 660.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(F)CCNCC3)ccc12 CHEMBL3666181 IC50 660.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNCC4)CC3)ccc12 CHEMBL1809162 IC50 670.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCC(N4CCNCC4)CC3)ccc12 CHEMBL3666082 IC50 670.0 nM
CSc1nn(-c2ccccc2)c2cc(C(=O)C3CCNCC3)ccc12 CHEMBL3666168 IC50 670.0 nM
C[C@]1(O)CCN(c2c(C#N)c(C(F)(F)F)nc3cc[nH]c23)C1 CHEMBL4063606 IC50 670.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)CC3CCNCC3)ccc12 CHEMBL1809160 IC50 680.0 nM
CCc1nn(-c2ccccc2)c2cc(NC(=O)c3cccc(C(=N)N)c3)ccc12 CHEMBL1809186 IC50 680.0 nM
Cc1nn(-c2ccccc2)c2cc(N3CCC(N)C3)ccc12 CHEMBL3666119 IC50 680.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)CN3CCNCC3)ccc12 CHEMBL3666162 IC50 680.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)NC3CCNCC3)ccc12 CHEMBL3666071 IC50 700.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(C)CCNCC3)ccc12 CHEMBL3666175 IC50 700.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CC4CC3CN4)ccc12 CHEMBL1809154 IC50 710.0 nM
CSc1nn(-c2ccccc2)c2cc(OC3CCNCC3)ccc12 CHEMBL1809155 IC50 710.0 nM
Cc1ccccc1Nc1nc(NC2CCNCC2)nc2c(NCC3CC3)ncnc12 CHEMBL2017241 IC50 710.0 nM
CSc1nn(-c2ccccc2)c2cc(NC3CCNCC3)ccc12 CHEMBL3666150 IC50 770.0 nM
CSc1nn(-c2ccccc2)c2cc(/C=C/C3CCCNC3)ccc12 CHEMBL3666187 IC50 790.0 nM
CSc1ccccc1Nc1nc(N2C3CCC2CC(N)C3)nc2c(NCC3CC3)ncnc12 CHEMBL2063921 IC50 800.0 nM
CSc1nn(-c2ccccc2)c2cc(N3CCN(C(=O)C4CCNCC4)CC3)ccc12 CHEMBL1809163 IC50 830.0 nM
COc1ccc(-n2nc(SC)c3ccc(N4CCNCC4)cc32)cc1 CHEMBL3666157 IC50 830.0 nM
C[C@H]1CCN1c1nc(N2CC[C@H](CCC(=O)O)C2)cc(C(F)(F)F)n1 CHEMBL5440941 IC50 849.1 nM
CCc1nn(-c2ccccc2)c2cc(N3CCNC(C)C3)ccc12 CHEMBL1809179 IC50 860.0 nM
CSc1nn(-c2ccccc2)c2cc(NC(=O)CC3CCCCN3)ccc12 CHEMBL3666069 IC50 860.0 nM
CCc1nn(-c2ccccc2)c2cc(N3CCC(N4CCNCC4)CC3)ccc12 CHEMBL3666096 IC50 890.0 nM
Cc1nn(-c2ccccc2)c2nc(-c3ccc(NC4CCNCC4)cc3)cc(O)c12 CHEMBL3666145 IC50 890.0 nM
CCN(CC1CCNCC1)c1ccc2c(SC)nn(-c3ccccc3)c2c1 CHEMBL3666149 IC50 890.0 nM
CSc1nn(-c2ccccc2)c2cc(NCCN3CCNCC3)ccc12 CHEMBL3666179 IC50 890.0 nM
CCc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)CC3)ccc12 CHEMBL1809183 IC50 920.0 nM
CSc1nn(-c2ccc(Br)cc2)c2cc(OCC3CCNCC3)ccc12 CHEMBL3666160 IC50 920.0 nM
CSc1nn(-c2ccccc2)c2cc(CCC3CCNCC3)ccc12 CHEMBL3666190 IC50 920.0 nM
CCc1nn(-c2ccccc2)c2cc(NC(=O)c3ccc4nc[nH]c4c3)ccc12 CHEMBL1809187 IC50 940.0 nM
CSc1nn(-c2ccccc2)c2cc(C(=O)CC3CCNCC3)ccc12 CHEMBL3666176 IC50 1000.0 nM