Cc1ccc(C(=O)N(CCCN)[C@@H](c2oc3cc(Cl)ccc3c(=O)c2Cc2ccccc2)C(C)C)cc1 CHEMBL2325429 IC50 0.14 nM
CC(=O)C1=NN(c2cc(C)ccc2F)C[C@@]1(CCCN(C)C)c1ccccc1 CHEMBL247044 IC50 0.2 nM
CC(=O)C1=NN(c2cc(C)ccc2F)C[C@]1(CCCN(C)C)c1ccccc1 CHEMBL4239814 IC50 0.2 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCOCC1)c1ccccc1 CHEMBL398478 IC50 0.4 nM
N[C@H](C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1)C1CC1 CHEMBL206115 IC50 0.5 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN)c1ccccc1 CHEMBL250127 IC50 0.5 nM
C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)nn1Cc1ccccc1)C(C)(C)C CHEMBL3645244 IC50 0.6 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1ccccc1)N(C[C@@H]1CNC[C@@H]1F)C(=O)[C@@H]1CCCO1 CHEMBL3645253 IC50 0.69 nM
C[C@@H]1CN(C(=O)N(C[C@@H]2CNC[C@@H]2F)[C@@H](c2nc(-c3cc(F)ccc3F)nn2Cc2cccc(F)c2)C(C)(C)C)C[C@H](C)O1 CHEMBL3645243 IC50 0.74 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(C[C@H](F)CN)c1ccccc1 CHEMBL400042 IC50 0.82 nM
C[C@@H]1CN(C(=O)N(C[C@@H]2CNC[C@@H]2F)[C@@H](c2nc(-c3cc(F)ccc3F)nn2Cc2ccccc2)C(C)(C)C)C[C@H](C)O1 CHEMBL3645242 IC50 0.83 nM
C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)C(C)(C)C CHEMBL3645246 IC50 0.83 nM
C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)C(C)(C)C CHEMBL3680846 IC50 0.84 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)N(C[C@@H]1CNC[C@@H]1F)C(=O)[C@H](C)O CHEMBL3645252 IC50 0.87 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN)c1ccccc1 CHEMBL241754 IC50 0.9 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCC(=O)N(C)CC1)c1ccccc1 CHEMBL251142 IC50 0.9 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)N(C[C@@H]1CNC[C@@H]1F)C(=O)[C@@H]1CCCO1 CHEMBL3645250 IC50 0.9 nM
CC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1ccccc1)N(C[C@@H]1CNC[C@@H]1F)C(=O)C1CCCO1 CHEMBL3645241 IC50 0.96 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CC[C@H](F)C1)c1ccccc1 CHEMBL240704 IC50 1.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CC2CCC1C2)c1ccccc1 CHEMBL398396 IC50 1.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1C[C@H]2C[C@@H]1CO2)c1ccccc1 CHEMBL240497 IC50 1.0 nM
CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2[C@@]1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL250126 IC50 1.0 nM
CC(=O)C1=NN2c3cc(C)ccc3OC[C@H]2[C@@]1(CCCN1CCOCC1)c1ccccc1 CHEMBL399378 IC50 1.0 nM
CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2[C@@]1(CCCN(C)C)c1ccccc1 CHEMBL429553 IC50 1.0 nM
CCC(c1nc2snc(C)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829430 IC50 1.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1cc(F)ccc1OC[C@H]2CCN CHEMBL3403387 EC50 1.0 nM
COc1ccc(NC(=O)C2=C(C)Nc3n[nH]cc3C2c2ccco2)cc1 CHEMBL1277017 IC50 1.1 nM
CC(C)[C@H](N)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1 CHEMBL381526 IC50 1.2 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CC2CC1CO2)c1ccccc1 CHEMBL246603 IC50 1.2 nM
Cc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1C CHEMBL2325410 Ki(app) 1.2 nM
Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1 CHEMBL2347651 IC50 1.2 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)N(CC[C@H](N)CF)C(=O)[C@@H]1CCCO1 CHEMBL3645247 IC50 1.23 nM
CC(C)(C)[C@H](O)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1 CHEMBL262736 IC50 1.3 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CCCC1)c1ccccc1 CHEMBL427688 IC50 1.3 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN(C)C)c1ccccc1 CHEMBL392148 IC50 1.4 nM
O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1 CHEMBL1222153 Ki 1.4 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1ccccc1)N(CC[C@H](N)CF)C(=O)[C@@H]1CCCO1 CHEMBL3645251 IC50 1.4 nM
CC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)N(C[C@@H]1CNC[C@@H]1F)C(=O)C1CCCO1 CHEMBL3645245 IC50 1.46 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)N(CC[C@H](N)CF)C(=O)[C@H](C)O CHEMBL3645248 IC50 1.49 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCNC(=O)CC1)c1ccccc1 CHEMBL438876 IC50 1.5 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL250125 IC50 1.6 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN(C)C)c1ccccc1 CHEMBL250328 IC50 1.6 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CC(F)C1)c1ccccc1 CHEMBL240498 IC50 1.8 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CCOCC1)c1ccccc1 CHEMBL239415 IC50 1.8 nM
CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2C1(CCCN1CCOCC1)c1ccccc1 CHEMBL250533 IC50 1.8 nM
CC(=O)C1=NN2c3cc(C)ccc3OC[C@H]2[C@@]1(CCCN(C)C)c1ccccc1 CHEMBL250532 IC50 1.8 nM
CN(C)C(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN)c1ccccc1 CHEMBL377566 IC50 1.9 nM
N[C@H](C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1)C1CC1 CHEMBL204459 IC50 2.0 nM
COCCN(C)CCC[C@@]1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(C)=O CHEMBL240705 IC50 2.0 nM
CC(=O)C1=NN(c2cc(C)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL443490 IC50 2.0 nM
CC(C)c1ccc2c(c1)[C@H]1O[C@@H](CNS(=O)(=O)CCCN(C)C)CC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1084143 IC50 2.0 nM
CN(C)CCS(=O)(=O)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Cl)cc(F)c1N[C@H]2c1ccccc1 CHEMBL1096003 IC50 2.0 nM
Cc1ccc(C(=O)N(CCCN)C(c2nc3snc(C)c3c(=O)n2Cc2ccccc2)C(C)C)cc1 CHEMBL1829433 IC50 2.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1ccccc1OC[C@H]2CCN CHEMBL3403385 EC50 2.0 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN(C)C)c1ccccc1 CHEMBL246604 IC50 2.1 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc2c(c1)CCCC2)C(=O)O CHEMBL2325414 Ki(app) 2.1 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CCCN)c1ccccc1 CHEMBL395332 IC50 2.2 nM
Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1 CHEMBL228814 Ki(app) 2.3 nM
COC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)nn1Cc1ccccc1)N(CC[C@H](N)CF)C(=O)[C@H](C)O CHEMBL3639441 IC50 2.34 nM
COc1ccc(NC(=O)C2=C(C)Nc3n[nH]cc3C2c2cccs2)cc1 CHEMBL1276930 IC50 2.5 nM
C[C@H](O)C(=O)N(CC[C@H](N)CF)[C@@H](c1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1)C(C)(C)C CHEMBL3680850 IC50 2.54 nM
CN(C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1)C1CCNCC1 CHEMBL205437 IC50 2.6 nM
C[C@H](O)C(=O)N(CC[C@H](N)CF)[C@@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)C(C)(C)C CHEMBL3680848 IC50 2.6 nM
CC(C)(C)[C@H](N)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL204408 IC50 2.7 nM
CC(=O)N1CCN(CCC[C@@]2(c3ccccc3)CC(c3cc(F)ccc3F)=NN2C(C)=O)CC1 CHEMBL239414 IC50 2.8 nM
O=C([C@@H](O)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1 CHEMBL377596 IC50 2.9 nM
CC(=O)C1=NN(c2cc(F)ccc2F)C[C@@]1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL249882 IC50 3.0 nM
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Br)cc(F)c1N[C@H]2c1ccccc1 CHEMBL1082248 IC50 3.0 nM
CCC(c1nc2sccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829424 IC50 3.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1cc(F)c(F)cc1OC[C@H]2CCN CHEMBL3403391 EC50 3.0 nM
Cc1ccc(C(CC[C@@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL2023001 Ki(app) 3.4 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1F CHEMBL243669 Ki 3.5 nM
CC(C)[C@H](N)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL379690 IC50 3.6 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL248400 IC50 3.8 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCCC1)c1ccccc1 CHEMBL246422 IC50 3.8 nM
CC(=O)C1=NN(c2cc(Cl)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL247414 IC50 3.9 nM
CN(CCO)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1 CHEMBL206798 IC50 4.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@@]1(CCCN1CCC(F)(F)C1)c1ccccc1 CHEMBL400041 IC50 4.0 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN(C)Cc1cc(C)no1)c1ccccc1 CHEMBL246000 IC50 4.0 nM
CNCCS(=O)(=O)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1 CHEMBL1084677 IC50 4.0 nM
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccc(O)cc1 CHEMBL1083517 IC50 4.0 nM
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(C)(C)C)ccc1N[C@H]2c1ccccc1 CHEMBL1086410 IC50 4.0 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCOCC1)c1ccccc1 CHEMBL246001 IC50 4.2 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc2ccccc2c1)C(=O)O CHEMBL261613 Ki(app) 4.2 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCN1CCNCC1)c1ccccc1 CHEMBL401476 IC50 4.3 nM
CCc1cc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)ccc1C CHEMBL2325412 Ki(app) 4.6 nM
CC(=O)C1=NN(c2cc(Br)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL392599 IC50 4.7 nM
CCc1cccc(C(SCCN)(c2ccccc2)c2cccc(O)c2)c1 CHEMBL2325421 Ki(app) 4.8 nM
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(C)(C)C)ccc1N[C@H]2c1cccs1 CHEMBL1077227 IC50 5.0 nM
CN(C)CCCC(=O)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Br)cc(F)c1N[C@H]2c1ccccc1 CHEMBL1085692 IC50 5.0 nM
CCC(c1nc2c(C)nsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829432 IC50 5.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)SC12c1ccccc1OCC2CCN CHEMBL3403382 EC50 5.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1cccc(F)c1OC[C@H]2CCN CHEMBL3403389 EC50 5.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1cc(F)cc(F)c1OC[C@H]2CCN CHEMBL3403390 EC50 5.0 nM
Cc1cccc(C(CCC(N)C(=O)O)(c2ccccc2)c2ccccc2)c1 CHEMBL2022994 Ki(app) 5.1 nM
CC(C)(CN)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL203045 IC50 5.2 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CC[C@H](N)C(F)F)c1ccccc1 CHEMBL395034 IC50 5.2 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CC[C@@H](N)C(F)F)c1ccccc1 CHEMBL240923 IC50 5.2 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CC(F)C1)c1ccccc1 CHEMBL248244 IC50 5.2 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@@]1(CCCO)c1ccccc1 CHEMBL250743 IC50 5.2 nM
CN(C(=O)N1CC(c2cc(F)ccc2F)=CC1c1cccc(O)c1)C1CCNCC1 CHEMBL206249 IC50 5.5 nM
CCc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022982 Ki(app) 5.9 nM
FC(F)(F)c1ccc2c(c1)[C@H]1O[C@@H](Cn3cncn3)CC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1093088 IC50 6.0 nM
CC(=O)NCCNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Br)cc(F)c1N[C@H]2c1ccccc1 CHEMBL1082249 IC50 6.0 nM
CON(C)C(=O)N1N=C(c2cc(F)ccc2F)S[C@@]1(CCCN)c1ccccc1 CHEMBL2347655 IC50 6.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL390629 Ki 6.2 nM
Cc1cccc(C(CC[C@@H](N)C(=O)O)(c2ccccc2)c2ccccc2)c1 CHEMBL2022996 Ki(app) 6.4 nM
CCc1cccc(C(CCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2325432 Ki(app) 6.4 nM
CC(C)c1cccc(C(CCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2325433 Ki(app) 6.7 nM
NC(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1F CHEMBL243668 Ki 6.8 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2cccc(O)c2)cc1 CHEMBL2321913 Ki(app) 6.8 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1 CHEMBL381533 IC50 7.0 nM
CN(C[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1)S(=O)(=O)CCCN CHEMBL1084678 IC50 7.0 nM
OCCNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(Cl)cc(F)c1N[C@H]2c1ccccc1 CHEMBL1096002 IC50 7.0 nM
NCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL1163678 IC50 7.0 nM
CCNCCS(=O)(=O)NC[C@@]1(c2ccccc2)SC(NC(=O)C(C)(C)C)=NN1C(=O)C(C)(C)C CHEMBL2105661 IC50 7.0 nM
C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1)C(C)(C)C CHEMBL3680849 IC50 7.18 nM
CC(C)(C)[C@H](NC(=O)OCCO)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL202788 IC50 7.4 nM
Cc1ccc(C(CCC(N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL2022999 Ki(app) 7.5 nM
CCc1cc(C(SCCN)(c2ccccc2)c2ccccc2)ccc1C CHEMBL2325413 Ki(app) 7.8 nM
Cc1ccc(C(CCC(N)C(=O)O)(c2ccccc2)c2cccc(O)c2)cc1 CHEMBL2325424 Ki(app) 7.8 nM
CN(C)C(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCN)c1ccccc1 CHEMBL208865 IC50 8.0 nM
CN(C)CCNC(=O)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1 CHEMBL1077204 IC50 8.0 nM
COc1ccc(C2(SC[C@H](N)C(=O)O)c3ccccc3C=Cc3ccccc32)cc1 CHEMBL3633535 IC50 8.6 nM
Cc1cccc(C(CCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022997 Ki(app) 8.8 nM
COc1ccc(C(CCC(N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL2325435 Ki(app) 9.0 nM
COc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL392369 Ki(app) 9.1 nM
Cc1ccc(C2(SC[C@H](N)C(=O)O)c3ccccc3CCc3ccccc32)cc1 CHEMBL3633526 IC50 9.3 nM
Cc1ccc(C(CCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL2023002 Ki(app) 9.7 nM
CCc1ccc(C(CCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL2325434 Ki(app) 9.7 nM
Cc1ccc(C(CCC(N)C(=O)O)(c2ccccc2)c2ccccc2)cc1C CHEMBL2325418 Ki(app) 9.9 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829246 IC50 10.0 nM
CC(C)(C)[C@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)N(C[C@@H]1CNC[C@@H]1F)C(=O)[C@@H]1CCCO1 CHEMBL3680847 IC50 10.0 nM
CC(=O)C1=NN(c2cc(C(F)(F)F)ccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL247594 IC50 10.1 nM
COc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)c(F)c1 CHEMBL2325406 Ki(app) 10.1 nM
COc1ccc(C(CCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL2325436 Ki(app) 10.1 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CCCNCCF)c1ccccc1 CHEMBL232460 IC50 10.2 nM
CCNCCC[C@@]1(c2ccccc2)C=C(c2cc(F)ccc2F)CN1C(=O)N(C)C CHEMBL389082 IC50 10.2 nM
CC(C)c1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022983 Ki(app) 10.3 nM
NCCSC(c1ccccc1)(c1ccccc1)c1ccc2c(c1)CCCC2 CHEMBL2325415 Ki(app) 10.6 nM
NCCCC(c1ccccc1)(c1ccccc1)c1ccc(Cl)cc1 CHEMBL2022998 Ki(app) 10.7 nM
O=C([C@@H](O)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL382165 IC50 11.0 nM
NC(=S)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL243885 IC50 11.0 nM
CCc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN)C3c1cccc(O)c1 CHEMBL590124 IC50 11.0 nM
O=C(NCCCO)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1 CHEMBL1085895 IC50 11.0 nM
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C3CC3)ccc1N[C@H]2c1ccccc1 CHEMBL1083836 IC50 11.0 nM
O=C1c2cc(N3CCCCC3)ccc2NC(Cc2ccccc2)N1c1ccc(O)cc1 CHEMBL1818768 IC50 11.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1ccccc1OC[C@@H]2CCN CHEMBL3403386 EC50 11.0 nM
N[C@@H](CSC1(c2ccc(Cl)cc2)c2ccccc2CCc2ccccc21)C(=O)O CHEMBL3633527 IC50 11.0 nM
Cc1cccc(C(CC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)c1 CHEMBL2022995 Ki(app) 11.1 nM
COc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)c(F)c1 CHEMBL2325407 Ki(app) 11.6 nM
CC[C@H](c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN(C)C)C(=O)c1ccc(Br)cc1 CHEMBL254190 IC50 12.0 nM
N[C@@H](CSC1(c2ccc(Cl)cc2)c2ccccc2C=Cc2ccccc21)C(=O)O CHEMBL3633537 IC50 12.0 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CCCNCC(F)F)c1ccccc1 CHEMBL232258 IC50 12.1 nM
CC(C)(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1cccc(O)c1 CHEMBL378547 IC50 13.0 nM
CCC(c1nc2ccoc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829422 IC50 13.0 nM
Cc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL429597 Ki(app) 13.6 nM
CN(C)CCOC(=O)NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1 CHEMBL1084676 IC50 14.0 nM
COc1ccc(C2(SC[C@H](N)C(=O)O)c3ccccc3CCc3ccccc32)cc1 CHEMBL3633366 IC50 14.0 nM
Cc1ccc(C2(SC[C@H](N)C(=O)O)c3ccccc3C=Cc3ccccc32)cc1 CHEMBL3633536 IC50 14.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c(F)c2)cc1 CHEMBL389589 IC50 15.0 nM
CN(CCCN)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL382587 IC50 16.0 nM
CCC(c1nc2onc(C)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829431 IC50 16.0 nM
CC(=O)C1=NN(c2cc(F)ccc2F)CC1(CCCN1CCS(=O)(=O)CC1)c1ccccc1 CHEMBL401006 IC50 16.5 nM
Cc1ccc(C(CC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL2023000 Ki(app) 16.7 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccc(O)c(F)c1)N2 CHEMBL1078774 IC50 17.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@@]12c1cc(Cl)ccc1OC[C@H]2CCN CHEMBL3403388 EC50 17.0 nM
CCOc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL2325430 Ki(app) 17.3 nM
NCCN(C[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1)c1ccccc1 CHEMBL1093087 IC50 19.0 nM
CCN(CCO)C[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(C)(C)C)ccc1N[C@H]2c1ccccc1 CHEMBL1084935 IC50 19.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(I)cc1)C(=O)O CHEMBL1688928 IC50 19.3 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN)C3c1cccc(O)c1 CHEMBL590123 IC50 20.0 nM
NC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccccc1 CHEMBL1085666 IC50 20.0 nM
O=c1c(Cc2ccccc2)c(-c2cccc(O)c2)[nH]c2ccc(N3CCCCC3)cc12 CHEMBL1818755 IC50 20.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1cccc(F)c1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829248 IC50 20.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)c(F)c1 CHEMBL1829406 IC50 20.0 nM
NCCC(=O)N1CCc2cc3c(cc2C1c1cccc(O)c1)OCO3 CHEMBL2347656 IC50 20.0 nM
CCC(c1nc2ccn(C)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829423 IC50 21.0 nM
N[C@@H](CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21)C(=O)O CHEMBL3633365 IC50 21.0 nM
COc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL1818529 Ki(app) 21.5 nM
CC(=O)C1=NN(c2ccccc2F)CC1(CCCN1CCN(C(C)=O)CC1)c1ccccc1 CHEMBL393647 IC50 21.8 nM
CSc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1688920 IC50 21.8 nM
O=c1c(Cc2ccccc2)c(-c2cccc(O)c2)[nH]c2ccc(N3CCOCC3)cc12 CHEMBL1818758 IC50 23.0 nM
O=c1cc(-c2ccc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc2)oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc(O)c12 CHEMBL3087419 IC50 23.0 nM
Nc1cc(-c2ccc(C(F)(F)F)cc2)ccc1NS(N)(=O)=O CHEMBL243431 IC50 24.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@H]1c1cccc(O)c1 CHEMBL195232 IC50 24.7 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1cccs1)N2 CHEMBL1078998 IC50 25.0 nM
O=C1c2cc(N3CCCC3)ccc2NC(Cc2ccccc2)N1c1ccc(O)cc1 CHEMBL1818774 IC50 25.0 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1C CHEMBL2325411 Ki(app) 25.7 nM
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCCC1 CHEMBL382790 IC50 26.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@H]1c1ccccc1 CHEMBL228815 IC50 26.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL392695 Ki app 26.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(Br)cc1)C(=O)O CHEMBL412132 IC50 26.8 nM
NCCC(=O)N1CCc2c([nH]c3ccc(Br)cc23)C1c1cccc(O)c1 CHEMBL592518 IC50 27.0 nM
O=c1cc(-c2ccc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)cc2)oc2cc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)cc(O)c12 CHEMBL3087418 IC50 27.0 nM
COc1ccc(C(CC(F)CN)(c2ccccc2)c2ccc(C)cc2)cc1 CHEMBL2325426 Ki(app) 27.3 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL1945658 Ki(app) 27.4 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(OC(F)(F)F)c1 CHEMBL2022988 Ki(app) 27.8 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c([N+](=O)[O-])c2)cc1 CHEMBL244697 IC50 28.0 nM
CCC(c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN(C)C)C(=O)c1ccc(Br)cc1 CHEMBL1164552 IC50 29.0 nM
CCCc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022984 Ki(app) 29.6 nM
NCCSC(c1ccccc1)(c1ccccc1)c1ccc(OC(F)(F)F)cc1 CHEMBL2325431 Ki(app) 29.7 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(Br)cc1 CHEMBL1829401 IC50 30.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc2ccccc2c1 CHEMBL1829420 IC50 30.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc3c(c2)OC(F)(F)O3)cc1 CHEMBL242181 IC50 31.0 nM
O=C1CCc2cc3c(cc2N1)[nH]c1cc(C(F)(F)F)ccc13 CHEMBL1802990 IC50 31.0 nM
NCCCC(c1ccccc1)(c1ccccc1)c1ccc(Cl)c(Cl)c1 CHEMBL2325417 Ki(app) 31.4 nM
O=C1c2cc(N3CCCCC3)ccc2NC(Cc2ccccc2)N1c1cccc(O)c1 CHEMBL1818767 IC50 33.0 nM
Cc1ccc(C(CCCN)(c2ccccc2)c2cccc(O)c2)cc1 CHEMBL2325425 Ki(app) 33.6 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccc(O)cc1)N2 CHEMBL1078691 IC50 34.0 nM
O=C1CSc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 CHEMBL3289009 IC50 35.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1ccc(Cl)c(Cl)c1 CHEMBL2325409 Ki(app) 35.2 nM
N[C@@H](CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2C=Cc2ccccc21)C(=O)O CHEMBL3633534 IC50 36.0 nM
O=C1Cc2cc3c(cc2N1)[nH]c1cc(C(F)(F)F)ccc13 CHEMBL1803019 IC50 37.0 nM
COc1ccc(C(CCCN)(c2ccccc2)c2ccccc2)c(F)c1 CHEMBL2325416 Ki(app) 37.9 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 CHEMBL380955 IC50 38.0 nM
O=c1cc(-c2ccccc2)oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])c(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])c(O)c12 CHEMBL3087420 IC50 38.0 nM
NC(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL243883 IC50 39.0 nM
NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL609588 IC50 39.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c(F)c2)cn1 CHEMBL470767 IC50 40.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1cccc(O)c1)N2 CHEMBL1078690 IC50 40.0 nM
NCCC(=O)N1CCc2c([nH]c3c(Cl)cccc23)C1c1cccc(O)c1 CHEMBL1163527 IC50 40.0 nM
O=C1CCc2c(ccc3c2[nH]c2cc(C(F)(F)F)ccc23)N1 CHEMBL1802989 IC50 40.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1cc2ccccc2s1 CHEMBL1829418 IC50 40.0 nM
O=C(c1ccc(O)cc1)N1CCc2cc3c(cc2C1c1cccc(O)c1)OCO3 CHEMBL2347653 IC50 40.0 nM
CCC(c1nc2ccccc2n1Cc1ccccc1)N(CCCN(C)C)C(=O)c1ccc(Br)cc1 CHEMBL2347652 IC50 40.0 nM
O=c1c(Cc2ccccc2)c(-c2ccc(O)cc2)[nH]c2ccc(N3CCCCC3)cc12 CHEMBL1818756 IC50 42.0 nM
NCCOCCOCCNC(=O)C(N)CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21 CHEMBL4754888 IC50 42.0 nM
NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 CHEMBL1164477 IC50 43.0 nM
O=[N+]([O-])c1ccc2[nH]c3cc(C(F)(F)F)ccc3c2c1 CHEMBL3288965 IC50 43.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCN)c1ccccc1 CHEMBL207006 IC50 44.0 nM
CC(C)(C)C(=O)NC1=NN(C(=O)C(C)(C)C)C(CNS(C)(=O)=O)(c2ccccc2)S1 CHEMBL3319301 IC50 44.0 nM
O=C1CCCc2cc3c(cc2N1)[nH]c1cc(C(F)(F)F)ccc13 CHEMBL1803020 IC50 45.0 nM
O=C1CCc2cc(Nc3cccc(C(F)(F)F)c3)ccc2N1 CHEMBL3288973 IC50 45.0 nM
CC(C)C(=O)N1N=C(NC(=O)C(C)(C)C)SC1(CCNS(C)(=O)=O)c1ccccc1 CHEMBL3319304 IC50 48.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1cccc(O)c1)C(=O)O CHEMBL2023004 Ki(app) 48.8 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CN)C3c1cccc(O)c1 CHEMBL595399 IC50 49.0 nM
O=C1c2cc(N3CCCC3)ccc2NC(Cc2ccccc2)N1c1cccc(O)c1 CHEMBL1818773 IC50 49.0 nM
CCN1C[C@@H](CN(C(=O)[C@@H]2CCCO2)[C@@H](c2nc(-c3cc(F)ccc3F)nn2Cc2cccc(F)c2)C(C)(C)OC)[C@@H](F)C1 CHEMBL3645249 IC50 49.41 nM
CC(=O)N1CCC(N(C)C(=O)N2CC(c3cc(F)ccc3F)=C[C@H]2c2ccccc2)CC1 CHEMBL208422 IC50 50.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)c1ccc(N)cc1)C3c1cccc(O)c1 CHEMBL1163584 IC50 50.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(Cl)cc1 CHEMBL1829399 IC50 50.0 nM
O=C1CCCc2cc(Nc3cccc(C(F)(F)F)c3)ccc2N1 CHEMBL3289006 IC50 50.0 nM
O=C1CCCc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 CHEMBL3289010 IC50 50.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)CC1c1cccc(O)c1 CHEMBL196329 IC50 51.0 nM
CC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 CHEMBL1164373 IC50 51.0 nM
Cc1c(-c2ccccc2)[nH]c2ccc(N3CCN(C)CC3)cc2c1=O CHEMBL1818674 IC50 51.0 nM
CC(=O)c1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL2022992 Ki(app) 51.0 nM
O=C1CSc2cc(Nc3cccc(C(F)(F)F)c3)ccc2N1 CHEMBL3289003 IC50 51.0 nM
FC(F)(F)c1ccc2c(c1)[nH]c1cnccc12 CHEMBL1802986 IC50 52.0 nM
O=C1CC(c2ccc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc2)Oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc(O)c21 CHEMBL3087430 IC50 52.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(Cl)cc1)C(=O)O CHEMBL409102 IC50 53.3 nM
CC(C)(C)c1ccc(-c2ccc(NC(N)=O)cc2)cc1 CHEMBL244126 IC50 54.0 nM
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCC1 CHEMBL210264 IC50 55.0 nM
CCc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1688921 IC50 55.4 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2cccc(C(N)=O)c2)cc1 CHEMBL2325423 Ki(app) 55.6 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2ccc(C)cc2)cc1 CHEMBL2325419 Ki(app) 56.0 nM
CN(C)CCNC(=O)C(N)CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21 CHEMBL4755438 IC50 56.0 nM
CC(C)c1ccc(-c2ccc(NC(N)=O)cc2)cc1 CHEMBL397249 IC50 57.0 nM
CCc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL1945653 Ki(app) 57.5 nM
NC(=O)Nc1ccc(-c2ccc(S(=O)(=O)C(F)(F)F)cc2)cc1 CHEMBL389588 IC50 58.0 nM
CNC[C@H]1CC[C@@H]2[C@H](O1)c1cc(C(F)(F)F)ccc1N[C@H]2c1ccc(F)cc1 CHEMBL1086409 IC50 58.0 nM
O=C1CCCc2c(ccc3c2[nH]c2cc(C(F)(F)F)ccc23)N1 CHEMBL1803021 IC50 58.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1ccc(Cl)cc1)C(=O)O CHEMBL2043400 IC50 58.6 nM
O=C1CC(c2ccc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])cc2)Oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])cc(O)c21 CHEMBL3087429 IC50 59.0 nM
Cc1ccc(C(=O)N(CCCN)C(c2nn3c(Cl)ccc3c(=O)n2Cc2ccccc2)C2CC2)cc1 CHEMBL213184 IC50 60.0 nM
CCC(c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL213686 IC50 60.0 nM
CCC(c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(Cl)cc1 CHEMBL209815 IC50 60.0 nM
Cc1ccc(C(=O)N2CCc3cc4c(cc3C2c2cccc(O)c2)OCO4)cc1 CHEMBL2347654 IC50 60.0 nM
N[C@@H](CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CSc2ccccc21)C(=O)O CHEMBL3633541 IC50 61.0 nM
O=c1c(-c2ccc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc2)coc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc(O)c12 CHEMBL3087428 IC50 63.0 nM
NS(=O)(=O)Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL396794 IC50 64.0 nM
CCC(=O)N1N=C(NC(=O)C(C)(C)C)SC1(CCNS(C)(=O)=O)c1ccccc1 CHEMBL3319303 IC50 64.0 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2cccc(C#N)c2)cc1 CHEMBL2325422 Ki(app) 64.2 nM
Cc1ccc(C(=O)N(CCN)C[C@H]2CC[C@@H]3[C@H](O2)c2cc(C(F)(F)F)ccc2N[C@H]3c2ccccc2)cc1 CHEMBL1084431 IC50 65.0 nM
NCCNC(=O)C1Cc2c([nH]c3ccccc23)C(c2cccc(O)c2)N1 CHEMBL1163528 IC50 65.0 nM
COc1cc(-c2ccc(C(F)(F)F)cc2)ccc1NS(N)(=O)=O CHEMBL242780 IC50 66.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCN)c1ccccc1 CHEMBL207992 IC50 67.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc3c(c2)OC(F)(F)C(F)(F)O3)cc1 CHEMBL397673 IC50 67.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1Cl CHEMBL243649 IC50 67.0 nM
O=c1c(-c2ccc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])cc2)coc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])cc(O)c12 CHEMBL3087426 IC50 67.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1cccc(O)c1)C(=O)O CHEMBL2043398 IC50 67.6 nM
O=C1CCc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 CHEMBL3288994 IC50 68.0 nM
CCC(c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL535161 IC50 70.0 nM
O=C1c2cc(N3CCCC3)ccc2NC(Cc2ccccc2)N1c1ccccc1 CHEMBL1818772 IC50 73.0 nM
CCOC(=O)C1Cc2c([nH]c3ccccc23)C(c2cccc(O)c2)N1C(=O)CC CHEMBL1164258 IC50 75.0 nM
N[C@@H](CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2COc2ccccc21)C(=O)O CHEMBL3633540 IC50 75.0 nM
Nc1ccc(C(=O)N2CCc3c([nH]c4ccc(Cl)cc34)C2c2cccc(O)c2)cc1 CHEMBL1164476 IC50 76.0 nM
O=c1c(-c2ccc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc2)coc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])ccc12 CHEMBL3087425 IC50 76.0 nM
CCC(C)C(SC[C@H](N)C(=O)O)(c1ccccc1)c1ccccc1 CHEMBL1688930 Ki(app) 76.2 nM
O=c1c(-c2ccc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)cc2)coc2cc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)cc(O)c12 CHEMBL3087427 IC50 78.0 nM
CCC(c1nn2cccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL214404 IC50 80.0 nM
Cc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022981 Ki(app) 80.0 nM
NC(CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21)C(=O)NCCO CHEMBL4791487 IC50 80.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(CCCN)C3c1cccc(O)c1 CHEMBL1163628 IC50 83.0 nM
CN(C)C(=O)N1N=C(c2cc(F)ccc2F)CC1c1ccccc1 CHEMBL196985 IC50 84.0 nM
O=C1CCc2c(ccc3[nH]c4cc(C(F)(F)F)ccc4c23)N1 CHEMBL1803016 IC50 84.0 nM
CCCCc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1688927 Ki(app) 84.2 nM
CC(C)(C)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1ccccc1 CHEMBL414860 IC50 85.0 nM
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCCCC1 CHEMBL381985 IC50 85.0 nM
NC(=O)Nc1ccc2c(c1)[nH]c1cc(C(F)(F)F)ccc12 CHEMBL1803017 IC50 85.0 nM
CCC(c1nc2sc(Cl)cc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829426 IC50 85.0 nM
CC(=O)Nc1ccc2c(c1)[nH]c1cc(C(F)(F)F)ccc12 CHEMBL3288964 IC50 85.0 nM
CCCc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1688922 IC50 85.9 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCCN)C3c1cccc(O)c1 CHEMBL595400 IC50 86.0 nM
COc1ccc(C(CC(F)(F)CN)(c2ccccc2)c2ccc(C)cc2)cc1 CHEMBL2325427 Ki(app) 88.4 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1cccc(Cl)c1)C(=O)O CHEMBL2022594 Ki(app) 89.9 nM
NCCCCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)N2C1=O CHEMBL399296 IC50 90.0 nM
Fc1cc(C(F)(F)F)cc2c1N[C@@H](c1ccccc1)[C@@H]1CCCO[C@H]21 CHEMBL1078572 IC50 90.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1cccc(C)c1 CHEMBL1828638 IC50 90.0 nM
CCc1ccc(C(=O)N(CCCN)C(CC)c2nc3ccsc3c(=O)n2Cc2ccccc2)cc1 CHEMBL1829407 IC50 90.0 nM
O=c1cc(-c2ccccc2)oc2cc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)c(O)c(O)c12 CHEMBL3087421 IC50 91.0 nM
O=C1c2cc(N3CCCCC3)ccc2NC(Cc2ccccc2)N1c1ccccc1 CHEMBL1818766 IC50 92.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)CC1c1ccccc1 CHEMBL365108 IC50 94.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccc(O)c(O)c1)N2 CHEMBL1078692 IC50 95.0 nM
FC(F)(F)c1ccc2c(c1)[nH]c1ccncc12 CHEMBL1802987 IC50 95.0 nM
O=c1cc(-c2ccc(O)cc2)oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])cc(O)c12 CHEMBL3087417 IC50 98.0 nM
N[C@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL399251 Ki(app) 98.6 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNCc1ccccc1)c1ccccc1 CHEMBL207993 IC50 100.0 nM
Cc1ccc(C(=O)N(CCCN)C(c2nn3ccc(Cl)c3c(=O)n2Cc2ccccc2)C2CC2)cc1 CHEMBL380294 IC50 100.0 nM
CCN(CC)C(=O)c1c(NC(=O)c2cccs2)sc2c1CC(C)CC2 CHEMBL388313 EC50 100.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN1CCCCC1)C3c1cccc(O)c1 CHEMBL594458 IC50 100.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN)C3c1cccc(F)c1 CHEMBL591331 IC50 100.0 nM
CC1=C(C(=O)Nc2ccc(Cl)cc2)C(c2ccccc2)C2=C(CC(C)(C)CC2=O)N1 CHEMBL1277474 IC50 100.0 nM
CC1=C(C(=O)c2ccccc2)C(c2cccc(O)c2)NC(=S)N1C CHEMBL1213953 IC50 100.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCN(C)C)c1ccccc1 CHEMBL210672 IC50 103.0 nM
Cc1ccc2c(c1C)CN(C(=O)N(C)C)C[C@@H]2c1cccc(O)c1 CHEMBL205786 IC50 104.0 nM
Cc1ccc(C(Cc2ccccc2)(SC[C@H](N)C(=O)O)c2ccc(C)cc2)cc1 CHEMBL2043415 IC50 106.5 nM
CS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL244933 Ki 110.0 nM
CN(C)C(=O)N1CC(c2cc(F)ccc2F)=C[C@@]1(CCCNCC(F)(F)F)c1ccccc1 CHEMBL232259 IC50 110.0 nM
CC1=C(C(=O)c2ccccc2)[C@@H](c2cccc(O)c2)NC(=S)N1C CHEMBL522806 IC50 110.0 nM
FC(F)(F)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1089057 IC50 110.0 nM
CC(C)(C)C(=O)N1N=C(c2cc(F)ccc2F)CC1c1ccccc1 CHEMBL206289 IC50 113.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(C(F)(F)F)cc1)C(=O)O CHEMBL232133 IC50 116.4 nM
NS(=O)(=O)Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL243701 IC50 118.0 nM
CCC(=O)N1C(C(=O)O)Cc2c([nH]c3ccccc23)C1c1cccc(O)c1 CHEMBL1164860 IC50 118.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCN1CC2C=CC1C2)c1ccccc1 CHEMBL378497 IC50 119.0 nM
COC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL232728 Ki app 120.0 nM
NS(=O)(=O)c1ccc(-c2ccc(C(F)(F)F)c(F)c2)cc1 CHEMBL450994 IC50 120.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1089056 IC50 120.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccsc1)N2 CHEMBL1084115 IC50 120.0 nM
NC(=O)Nc1ccc2[nH]c3cc(C(F)(F)F)ccc3c2c1 CHEMBL1803018 IC50 120.0 nM
CC(C)(C)C(=O)NC1=NN(C(=O)C(C)(C)C)C(CCNS(C)(=O)=O)(c2ccccc2)S1 CHEMBL3319302 IC50 120.0 nM
NCCCC(c1ccccc1)(c1ccccc1)c1cccc(Cl)c1 CHEMBL2022993 Ki(app) 120.6 nM
NCCCC1(c2ccccc2)CC(c2cc(F)ccc2F)=NN1C(=O)N1CCOCC1 CHEMBL210741 IC50 122.0 nM
O=c1cc(-c2ccccc2)oc2cc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)cc(O)c12 CHEMBL3087415 IC50 122.0 nM
O=c1cc(-c2ccccc2)oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c3[N+](=O)[O-])cc(O)c12 CHEMBL3087416 IC50 123.0 nM
COc1ccc(C(SC[C@H](N)CO)(c2ccccc2)c2ccccc2)cc1 CHEMBL1818527 IC50 127.0 nM
NC(CCC(c1ccccc1)(c1ccccc1)c1ccc(O)cc1)C(=O)O CHEMBL2325437 Ki(app) 128.6 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1cccc(Cl)c1)C(=O)O CHEMBL2043397 IC50 128.9 nM
CCc1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1089050 IC50 130.0 nM
CC(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1092159 IC50 130.0 nM
COc1ccc(C(SC[C@@H](N)CO)(c2ccccc2)c2ccccc2)cc1 CHEMBL1818528 IC50 130.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccc(C)cc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829250 IC50 130.0 nM
O=c1cc(-c2ccccc2)oc2cc(Oc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[N+](=O)[O-])cc(O)c12 CHEMBL3087414 IC50 134.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL2043387 IC50 138.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402337 EC50 139.0 nM
CC1=C(C(=O)Nc2ccc(F)cc2)C(c2ccccc2)c2c[nH]nc2N1 CHEMBL1276845 IC50 140.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1F)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829247 IC50 140.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(F)cc1 CHEMBL1829410 IC50 140.0 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1ccc(Cl)cc1 CHEMBL2043408 IC50 140.9 nM
Cc1cc(-c2ccc(C(F)(F)F)cc2)ccc1NS(N)(=O)=O CHEMBL242357 IC50 141.0 nM
CCC(c1nc2sc(Br)cc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829425 IC50 141.0 nM
CC(C)c1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1688923 IC50 144.0 nM
O=c1c(Cc2ccccc2)c(-c2ccccc2)[nH]c2ccc(N3CCCCC3)cc12 CHEMBL1818754 IC50 146.0 nM
NC(CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21)C(=O)NCCN1CCCCC1 CHEMBL4758507 IC50 146.0 nM
CC1Nc2ccc(N3CCCC3)cc2C(=O)N1c1ccc(O)cc1 CHEMBL1818765 IC50 149.0 nM
O=c1c(-c2ccc(O)cc2)coc2cc(Oc3c([N+](=O)[O-])cc([N+](=O)[O-])cc3C(F)(F)F)ccc12 CHEMBL3087424 IC50 149.0 nM
COc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022986 Ki(app) 149.8 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(F)cc1)C(=O)O CHEMBL412251 Ki app 150.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL408072 Ki app 150.0 nM
CC(C)C(SC[C@H](N)C(=O)O)(c1ccccc1)c1ccccc1 CHEMBL259257 Ki app 150.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(Cl)cc1Cl CHEMBL1829400 IC50 150.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc2c(c1)OCO2 CHEMBL1829421 IC50 150.0 nM
CC1=C(C(=O)c2ccccc2)[C@H](c2cccc(O)c2)NC(=S)N1C CHEMBL491384 IC50 150.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1ccc(F)cc1)C(=O)O CHEMBL2043399 IC50 150.5 nM
CC(=O)C1=NN2c3cc(F)ccc3OC[C@H]2[C@H]1c1ccccc1 CHEMBL251103 IC50 155.0 nM
CS(=O)(=O)NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL589153 IC50 155.0 nM
COc1ccc(-c2coc3cc(Oc4c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c4[N+](=O)[O-])ccc3c2=O)cc1 CHEMBL3087423 IC50 157.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1ccc(O)cc1)C(=O)O CHEMBL2043402 IC50 159.4 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccc(OC)cc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829251 IC50 160.0 nM
CC(C)(C)c1cccc(Nc2ccc3c(c2)CCC(=O)N3)c1 CHEMBL3288983 IC50 160.0 nM
N[C@@H](CSC1(c2cccc(Cl)c2)c2ccccc2CCc2ccccc21)C(=O)O CHEMBL3633532 IC50 160.0 nM
CCC(c1nc2sc(Cl)c(Br)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829427 IC50 161.0 nM
CC1Nc2ccc(N3CCOCC3)cc2C(=O)N1c1ccccc1 CHEMBL1818761 IC50 162.0 nM
COc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1F CHEMBL2325408 Ki(app) 162.2 nM
CCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 CHEMBL1163729 IC50 163.0 nM
Nc1cc(-c2ccc(NS(N)(=O)=O)cc2)ccc1C(F)(F)F CHEMBL395487 IC50 167.0 nM
Cc1ccc(C(Cc2ccccc2)(SC[C@H](N)C(=O)O)c2ccccc2)cc1 CHEMBL2043401 IC50 167.6 nM
COc1ccc(-c2coc3cc(Oc4c([N+](=O)[O-])cc(C(F)(F)F)cc4[N+](=O)[O-])ccc3c2=O)cc1 CHEMBL3087422 IC50 168.0 nM
CCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL1163891 IC50 169.0 nM
CC1Nc2ccc(N3CCCC3)cc2C(=O)N1c1ccccc1 CHEMBL1818763 IC50 169.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1F)N2 CHEMBL1078893 IC50 170.0 nM
CC1=C(C(=O)Nc2ccc(F)c(Cl)c2)C(c2ccccc2)c2c[nH]nc2N1 CHEMBL1276844 IC50 170.0 nM
FC(F)(F)c1ccc2c(c1)[nH]c1cc3[nH]ccc3cc12 CHEMBL1803022 IC50 170.0 nM
CC1Nc2ccc(N3CCCC3)cc2C(=O)N1c1cccc(O)c1 CHEMBL1818764 IC50 170.0 nM
COc1ccc(-c2coc3cc(Oc4c([N+](=O)[O-])cc([N+](=O)[O-])cc4C(F)(F)F)ccc3c2=O)cc1 CHEMBL3085794 IC50 170.0 nM
Cc1ccc(C(Cc2ccccc2)(SCCN)c2ccccc2)cc1 CHEMBL2043409 IC50 171.9 nM
N[C@H](CCC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL2022590 Ki(app) 173.5 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)C1CCCCC1)C(=O)O CHEMBL270138 Ki app 175.0 nM
CCCCC(SC[C@H](N)C(=O)O)(c1ccccc1)c1ccccc1 CHEMBL259256 Ki app 175.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCN)C3c1ccccc1 CHEMBL589393 IC50 175.0 nM
CS(=O)(=O)Nc1ccc(-c2ccc(S(=O)(=O)C(F)(F)F)cc2)cc1 CHEMBL243906 IC50 176.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)O CHEMBL2043413 IC50 178.2 nM
CC(=O)N1N=C(c2cc(F)ccc2F)SC12CCNc1ccccc12 CHEMBL3402340 EC50 179.0 nM
O=C1CCc2cc3[nH]c4cc(C(F)(F)F)ccc4c3cc2N1 CHEMBL1802991 IC50 180.0 nM
CC(=O)c1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022990 Ki(app) 185.8 nM
NCCS(=O)(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL595526 IC50 186.0 nM
CCC(c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(Cl)cc1 CHEMBL210168 IC50 190.0 nM
FC(F)(F)c1cccc(Nc2ccc3c(c2)CCC(=S)N3)c1 CHEMBL3289005 IC50 190.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1ccc(Cl)c(Cl)c1)C(=O)O CHEMBL2043403 IC50 191.2 nM
N#Cc1cc(-c2ccc(C(F)(F)F)cc2)ccc1NS(N)(=O)=O CHEMBL243681 IC50 196.0 nM
CC1(C)CC(=O)C2=C(C1)NC(=S)NC2c1cccc(O)c1 CHEMBL394880 IC50 200.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc2c(c1)OCO2)C(=O)O CHEMBL261611 Ki app 200.0 nM
NCCC(=O)N1CCc2c([nH]c3ccc(OC(F)(F)F)cc23)C1c1cccc(O)c1 CHEMBL592519 IC50 200.0 nM
CC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1cccc(O)c1 CHEMBL591332 IC50 200.0 nM
CC1(C)CC(=O)C2=C(C1)NC(=S)N[C@H]2c1cccc(O)c1 CHEMBL1213955 IC50 200.0 nM
CC1=C(C(=O)Nc2ccc([N+](=O)[O-])cc2)C(c2ccccc2)c2c[nH]nc2N1 CHEMBL1278186 IC50 200.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccccc1 CHEMBL1829270 IC50 200.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(O)c1 CHEMBL2023005 Ki(app) 200.3 nM
NCCSC(c1ccccc1)(c1cccc(O)c1)c1cccc(Cl)c1 CHEMBL2325420 Ki(app) 200.3 nM
Cc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)c(F)c1 CHEMBL2325405 Ki(app) 201.3 nM
NCCCC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL2022591 Ki(app) 203.0 nM
NCCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL1163677 IC50 204.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)S[C@]12c1ccccc1OC[C@H]2CCN CHEMBL3403383 EC50 205.0 nM
N[C@@H](CSC1(c2ccccc2)c2ccccc2CCc2ccccc21)C(=O)O CHEMBL3633364 IC50 209.0 nM
FC(F)(F)c1ccc2c(c1)[nH]c1ccccc12 CHEMBL1173704 IC50 210.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccc(Cl)cc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829249 IC50 210.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C(F)(F)F)cc1 CHEMBL1829402 IC50 210.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(OC)cc1 CHEMBL1829409 IC50 210.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)C(C)C)C3c1c[nH]c2ccccc12 CHEMBL1164553 IC50 216.0 nM
C[C@H](O)C(=O)N(CC[C@H](N)CF)[C@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)C(C)(C)C CHEMBL3680853 IC50 216.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccccc1)c1ccccc1F)C(=O)O CHEMBL2043396 IC50 216.8 nM
CC(=O)NC1=NN(C(C)=O)[C@](C)(c2ccccc2)S1 CHEMBL4283764 Kd 220.0 nM
CCCC(=O)N1C(C(=O)OCC)Cc2c([nH]c3ccccc23)C1c1cccc(O)c1 CHEMBL1164859 IC50 224.0 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1ccc(Cl)c(Cl)c1 CHEMBL2043411 IC50 229.3 nM
NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1C1CCCCC1 CHEMBL591330 IC50 230.0 nM
COc1ccc(C(SC[C@@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1818525 IC50 230.0 nM
Cc1c(-c2cccc(O)c2)[nH]c2ccc(N3CCCCC3)cc2c1=O CHEMBL1818747 IC50 232.0 nM
NC(CCC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL2022588 Ki(app) 235.4 nM
Cc1ccc2[nH]c3c(c2c1)CCN(CCN)C3c1cccc(O)c1 CHEMBL1163163 IC50 237.0 nM
N[C@@H](CSC(Cc1cccc(Cl)c1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL2043391 IC50 237.5 nM
N[C@@H](CSC1(c2cccc(C(F)(F)F)c2)c2ccccc2CCc2ccccc21)C(=O)O CHEMBL3633531 IC50 238.0 nM
N[C@@H](CCC(=O)C[C@@H](CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21)C(=O)O)C(=O)O CHEMBL4756522 IC50 239.0 nM
NC(=O)Nc1ccc(-c2ccc(SC(F)(F)F)cc2)cc1 CHEMBL244511 IC50 240.0 nM
CC(C)(C)c1ccc2[nH]c3ccccc3c2c1 CHEMBL1170621 IC50 240.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)SC12COc1ccccc12 CHEMBL3402336 EC50 246.0 nM
CC(=S)N1N=C(c2cc(F)ccc2F)CC1c1ccccc1 CHEMBL194980 IC50 250.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)O CHEMBL2043414 IC50 251.8 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1cccc(O)c1 CHEMBL2043406 IC50 256.1 nM
Cc1ccc(C(Cc2ccccc2)(SCCN)c2ccc(C)cc2)cc1 CHEMBL2043419 IC50 261.0 nM
NC(=O)Nc1ccc(-c2ccc(Br)c(F)c2)cc1F CHEMBL244510 IC50 262.0 nM
CN(C)CCCC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402352 EC50 263.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccc(F)cc1)N2 CHEMBL1078894 IC50 270.0 nM
Nc1ccc2c(c1)[nH]c1cc(C(F)(F)F)ccc12 CHEMBL3288963 IC50 270.0 nM
CC(=O)c1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL2022991 Ki(app) 271.7 nM
Cc1ccc(C(=O)N(CCCN)Cc2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)cc1 CHEMBL254192 IC50 280.0 nM
CNC(=O)N1N=C(c2cc(F)ccc2F)CC1(C)c1ccccc1 CHEMBL206883 IC50 284.0 nM
CCC(c1nn2c(Cl)cc(Cl)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL213736 IC50 290.0 nM
O=C(NCCO)C1Cc2c([nH]c3ccccc23)C(c2cccc(O)c2)N1 CHEMBL1165017 IC50 290.0 nM
O=C1COc2cc(Nc3cccc(C(F)(F)F)c3)ccc2N1 CHEMBL3289002 IC50 290.0 nM
Cc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1F CHEMBL2325404 Ki(app) 293.6 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(Br)c1 CHEMBL2022980 Ki(app) 293.9 nM
N[C@H](CO)CSC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL1818526 EC50 294.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(Cl)c1 CHEMBL2022979 Ki(app) 297.8 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccc(Cl)s1)N2 CHEMBL1084116 IC50 300.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1C(c1ccccc1)N2 CHEMBL1096347 IC50 300.0 nM
CC(C)(C)c1ccc2c(c1)[nH]c1ccccc12 CHEMBL1173703 IC50 300.0 nM
CC(C)(C)c1ccc(C2(SC[C@H](N)C(=O)O)c3ccccc3CCc3ccccc32)cc1 CHEMBL3633530 IC50 301.0 nM
CCC(CC)C(SC[C@H](N)C(=O)O)(c1ccccc1)c1ccccc1 CHEMBL1688931 Ki(app) 302.1 nM
Cc1ccc2c(c1C)CN(C(=O)N(C)C)CC2c1cccc(O)c1 CHEMBL380367 IC50 306.0 nM
N[C@@H](CSC1(c2ccc(Oc3ccccc3)cc2)c2ccccc2CCc2ccccc21)C(=O)O CHEMBL3633529 IC50 306.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CC1CNCCO1)C(=O)c1ccc(C)cc1 CHEMBL1829259 IC50 310.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1cccc(C(F)(F)F)c1 CHEMBL1829403 IC50 310.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1ccc(CO)cc1 CHEMBL2024130 Ki(app) 311.2 nM
CN(C)C(=O)N1Cc2cc(I)ccc2C(c2cccc(O)c2)C1 CHEMBL382364 IC50 317.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc3c(c2)C(F)(F)OC(F)(F)O3)cc1 CHEMBL244329 IC50 319.0 nM
CC1=C(C(=O)Nc2ccc(C(F)(F)F)cc2)C(c2cccs2)c2c[nH]nc2N1 CHEMBL1277016 IC50 320.0 nM
CCC(c1nc2ncccc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829428 IC50 323.0 nM
NC(=O)c1cccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)c1 CHEMBL2024124 Ki(app) 329.9 nM
CCC(c1nn2cc(Cl)cc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL210067 IC50 330.0 nM
NC(=O)Nc1ccc(-c2ccc(C3(C(F)(F)F)N=N3)cc2)cc1 CHEMBL1222255 Ki 330.0 nM
FC(F)(F)c1ccc2c(c1)[nH]c1cccnc12 CHEMBL1802988 IC50 330.0 nM
O=C1CCc2cc(Nc3ccc(C(F)(F)F)cc3)ccc2N1 CHEMBL3288976 IC50 330.0 nM
Cc1c(-c2cccc(O)c2)[nH]c2ccc(N3CCN(C)CC3)cc2c1=O CHEMBL1818675 IC50 334.0 nM
CC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 CHEMBL1165578 IC50 337.0 nM
NCCCC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402350 EC50 338.0 nM
CCc1cccc2c1CN(C(=O)N(C)C)CC2c1cccc(O)c1 CHEMBL438073 IC50 344.0 nM
NS(=O)(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL242783 IC50 345.0 nM
NCCCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL1165475 IC50 347.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1O CHEMBL243215 IC50 349.0 nM
Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1F CHEMBL436624 Ki 350.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1cccc(F)c1)N2 CHEMBL1077357 IC50 350.0 nM
O=C1CCCC2=C1[C@H](c1cc(O)ccc1Br)NC(=S)N2 CHEMBL2347798 IC50 350.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(C(F)(F)F)c1 CHEMBL2022985 Ki(app) 352.7 nM
NC(CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2CCc2ccccc21)C(=O)NCc1ccccc1 CHEMBL4750317 IC50 358.0 nM
CCCc1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1089051 IC50 360.0 nM
Cc1c(-c2ccccc2)[nH]c2ccc(N3CCCCC3)cc2c1=O CHEMBL1818677 IC50 360.0 nM
CNCCCC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402351 EC50 367.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(F)c1 CHEMBL2022593 Ki(app) 377.4 nM
CCOC(=O)C1Cc2c([nH]c3ccccc23)C(c2cccc(O)c2)N1C(=O)C(C)C CHEMBL1165484 IC50 380.0 nM
N[C@@H](CCC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL2022589 Ki(app) 384.4 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCN)c1ccccc1 CHEMBL207261 IC50 390.0 nM
COC(=O)c1ccc2[nH]c3cc(C(C)(C)C)ccc3c2c1 CHEMBL1173167 IC50 390.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCCN)C(=O)c1ccc(C)cc1 CHEMBL1829258 IC50 390.0 nM
NC(=O)Nc1ccc(Nc2cccc(C(F)(F)F)c2)cc1 CHEMBL3288972 IC50 390.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1ccccn1)c1ccccc1 CHEMBL425420 IC50 391.0 nM
CC1=C(C(=O)Nc2ccc(C(F)(F)F)cc2)C(c2ccccc2)c2c[nH]nc2N1 CHEMBL1278187 IC50 400.0 nM
CC1=C(C(=O)Nc2ccc(F)c(Cl)c2)C(c2ccco2)c2c[nH]nc2N1 CHEMBL1277198 IC50 400.0 nM
NCCSC(Cc1ccccc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 CHEMBL2043418 IC50 403.7 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1sccc1C CHEMBL1829415 IC50 410.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(C(N)=O)c1 CHEMBL2024125 Ki(app) 419.7 nM
CC(C)(C)c1cccc(-c2ccncc2)c1 CHEMBL449439 IC50 420.0 nM
Cc1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1088740 IC50 420.0 nM
CC(C)(C)c1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1688926 Ki(app) 428.6 nM
CC(C)c1cccc(Nc2ccc3c(c2)CCC(=O)N3)c1 CHEMBL3288982 IC50 430.0 nM
O=C1CCc2cc(Nc3cccc(C(F)(F)F)c3)cc(F)c2N1 CHEMBL3289007 IC50 430.0 nM
N#Cc1ccc(C(SCCN)(c2ccccc2)c2ccccc2)cc1 CHEMBL2024129 Ki(app) 432.4 nM
NCCSC(Cc1ccccc1)(c1ccc(Cl)cc1)c1cccc(Cl)c1 CHEMBL2043416 IC50 436.7 nM
CC1=C(C(=O)Nc2ccc(F)c(Cl)c2)C(c2cccs2)c2c[nH]nc2N1 CHEMBL1278004 IC50 440.0 nM
O=C1CCc2cc(Nc3cccc([N+](=O)[O-])c3)ccc2N1 CHEMBL3288990 IC50 440.0 nM
CC(=O)N1N=C(c2ccccc2Cl)CC1c1cccc(O)c1 CHEMBL364452 IC50 450.0 nM
CCC(SC[C@H](N)C(=O)O)(c1ccccc1)c1ccccc1 CHEMBL405609 Ki app 450.0 nM
N#Cc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2023006 Ki(app) 450.6 nM
CCC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402343 EC50 452.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(CCCCN)C3c1cccc(O)c1 CHEMBL1163629 IC50 454.0 nM
N[C@@H](CSC(Cc1ccc(Cl)cc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL2043392 IC50 455.8 nM
COc1ccc(Nc2nc3cc(C(=O)O)ccc3n2Cc2ccccc2C(F)(F)F)cc1F CHEMBL558476 IC50 458.8 nM
CC(C)(C)C(=O)N1N=C(c2ccccc2Cl)CC1c1cccc(O)c1 CHEMBL370956 IC50 460.0 nM
CCC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1cccc(O)c1 CHEMBL601305 IC50 460.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C)C3c1cccc(O)c1 CHEMBL1163742 IC50 462.0 nM
CCN(CC)C(=O)c1c(NC(=O)c2cccs2)sc2c1CCCC2 CHEMBL228369 EC50 480.0 nM
CC1(C)Oc2ccc(-c3ccc(NS(N)(=O)=O)cc3)cc2O1 CHEMBL242182 IC50 482.0 nM
CC(N)C(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL1163525 IC50 483.0 nM
N#CCc1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1083521 IC50 500.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccco1 CHEMBL1829413 IC50 500.0 nM
NS(=O)(=O)Nc1c(F)cc(-c2ccc(C(F)(F)F)cc2)cc1F CHEMBL241936 IC50 502.0 nM
FC(F)(F)Oc1ccc2c(c1)[nH]c1ccccc12 CHEMBL1171980 IC50 510.0 nM
N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccncc1)C(=O)O CHEMBL2043420 IC50 514.2 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1cccc(Cl)c1 CHEMBL2043405 IC50 519.0 nM
CC(=O)c1cccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)c1 CHEMBL2022989 Ki(app) 519.8 nM
CSc1ccc(Nc2nc3cc(C(N)=O)ccc3n2Cc2ccccc2C(F)(F)F)cc1 CHEMBL561696 IC50 520.0 nM
CC(C)CC(=O)NC1=NN(C(=O)CC(C)C)C(C)(c2ccccc2)S1 CHEMBL3356912 IC50 520.0 nM
CSc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2022987 Ki(app) 520.4 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1nccs1)N2 CHEMBL1084391 IC50 530.0 nM
O=C(Nc1sc2c(c1C(=O)N1CCCCC1)CCCC2)c1cccs1 CHEMBL390303 EC50 540.0 nM
Fc1c(Cl)ccc2c1N[C@@H](c1ccccc1)[C@@H]1CCCO[C@H]21 CHEMBL1077337 IC50 540.0 nM
Nc1ccc2[nH]c3cc(C(F)(F)F)ccc3c2c1 CHEMBL3288966 IC50 550.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1ncc[nH]1)c1ccccc1 CHEMBL209310 IC50 552.0 nM
N[C@@H](CSC(Cc1ccccc1)(c1ccc(Cl)cc1)c1cccc(Cl)c1)C(=O)O CHEMBL2043412 IC50 567.5 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1ccc(F)cc1 CHEMBL2043407 IC50 577.9 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCC[N+](C)(C)[O-])c1ccccc1 CHEMBL378184 IC50 585.0 nM
NCCSC(Cc1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL2043417 IC50 587.8 nM
Cc1ccc2c(c1)CN(C(=O)N(C)C)CC2c1cccc(O)c1 CHEMBL427386 IC50 595.0 nM
COc1ccc(C(SC[C@H](N)C(=O)O)(c2ccccc2)c2ccc(OC)cc2)cc1 CHEMBL272404 Ki app 600.0 nM
COC(=O)[C@@H](NC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(C)C CHEMBL409317 Ki app 600.0 nM
Cc1ccsc1CCN1C(=S)N(c2ccc(F)cc2)C(=O)C1CC(=O)Nc1ccc(F)cc1 CHEMBL2031570 IC50 600.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCO)c1ccccc1 CHEMBL382406 IC50 606.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccccc1Cl CHEMBL1829398 IC50 610.0 nM
O=C(CO)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402346 EC50 615.0 nM
COc1ccc2c(c1)CN(C(=O)N(C)C)CC2c1cccc(O)c1 CHEMBL205441 IC50 617.0 nM
NCCC(=O)N1CCc2c([nH]c3ccccc23)C1c1cccc(O)c1 CHEMBL590607 IC50 630.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1cc(C)on1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829256 IC50 630.0 nM
C[C@H](O)C(=O)N(CC[C@H](N)CF)[C@H](c1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1)C(C)(C)C CHEMBL3680852 IC50 631.0 nM
CN(C)C(=O)N1Cc2c(ccc3c2OCC3)C(c2cccc(O)c2)C1 CHEMBL381794 IC50 639.0 nM
CCC(c1nn2cccc2c(=O)n1Cc1ccccc1)N(CCC(C)(C)N)C(=O)c1ccc(Cl)cc1 CHEMBL377009 IC50 650.0 nM
O=C1[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)N2C(=O)N1Cc1ccccc1 CHEMBL2347649 IC50 650.0 nM
CN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL1163890 IC50 664.0 nM
CC(=O)NC1=NN(C(C)=O)C(C)(c2ccccc2)S1 CHEMBL1413473 Kd 664.5 nM
COCC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 CHEMBL3402347 EC50 665.0 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1ccc(O)cc1 CHEMBL2043410 IC50 665.6 nM
COC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccc(OC)cc1 CHEMBL400633 IC50 680.0 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL2043388 IC50 684.5 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cc2)c(F)c1 CHEMBL398232 IC50 685.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1c[nH]cn1)c1ccccc1 CHEMBL208864 IC50 686.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCO)c1ccccc1 CHEMBL383402 IC50 697.0 nM
Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL244264 IC50 700.0 nM
NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cn2)cc1 CHEMBL470776 IC50 700.0 nM
Oc1cccc(C2c3[nH]c4ccc(Cl)cc4c3CCN2Cc2ccccc2)c1 CHEMBL1163892 IC50 710.0 nM
NC(=O)Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL394512 IC50 716.0 nM
Clc1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1089393 IC50 720.0 nM
CCOC(=O)C1Cc2c([nH]c3ccccc23)C(c2cccc(O)c2)N1C(C)=O CHEMBL1164257 IC50 724.0 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCO)c1ccccc1 CHEMBL383759 IC50 745.0 nM
N[C@@H](COC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O CHEMBL412292 Ki app 750.0 nM
CC(C)[C@H](N)C(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL603050 IC50 760.0 nM
NCCC(=O)N1CCc2c([nH]c3ccc(F)cc23)C1c1cccc(O)c1 CHEMBL589879 IC50 760.0 nM
CCC(c1nc2ccsc2c(=O)n1CC1CC1)N(CCCN)C(=O)c1ccc(C)cc1 CHEMBL1829252 IC50 760.0 nM
NCCSC(Cc1ccccc1)(c1ccccc1)c1ccccc1F CHEMBL2043404 IC50 789.5 nM
CS(=O)(=O)Nc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1 CHEMBL430383 IC50 792.0 nM
CC(=O)C1=NN2c3ccccc3OC[C@H]2[C@H]1c1ccccc1 CHEMBL249883 IC50 800.0 nM
CCCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)N2C1=O CHEMBL252340 IC50 800.0 nM
CCCCN1C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3cccc(O)c3)N2C1=O CHEMBL4089675 IC50 800.0 nM
CN(C)C(=O)N1Cc2cc(Br)ccc2C(c2cccc(O)c2)C1 CHEMBL438800 IC50 808.0 nM
CCc1cccc(Nc2ccc3c(c2)CCC(=O)N3)c1 CHEMBL3288981 IC50 810.0 nM
O=c1[nH]c2ccc(Nc3cccc(C(F)(F)F)c3)cc2s1 CHEMBL3289001 IC50 810.0 nM
CC1=C(C(=O)Nc2ccc([N+](=O)[O-])cc2)C(c2cccs2)c2c[nH]nc2N1 CHEMBL1276931 IC50 820.0 nM
O=c1c(Cc2ccccc2)c(-c2ccccc2)[nH]c2ccc(N3CCOCC3)cc12 CHEMBL1818757 IC50 828.0 nM
CC(=O)NCc1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2024122 Ki(app) 829.2 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(CN)c1 CHEMBL2024121 Ki(app) 838.2 nM
N#C/N=C(\N)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL244075 IC50 840.0 nM
CC(=O)NC1=NN(C(C)=O)C(C)(c2cc(F)ccc2F)S1 CHEMBL3735751 IC50 840.0 nM
CS(=O)(=O)c1ccc(-c2ccc(C(F)(F)F)c(F)c2)cc1 CHEMBL472473 IC50 860.0 nM
O=C(CC1CCNCC1)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 CHEMBL590855 IC50 860.0 nM
CC(C)(C)c1ccc2c(c1)[C@H]1OCCC[C@H]1C(c1cccc(F)c1)N2 CHEMBL1098378 IC50 870.0 nM
FC(F)c1ccc2c(c1)[nH]c1ccccc12 CHEMBL1170284 IC50 870.0 nM
CNC(=O)c1cccc(C(SCCN)(c2ccccc2)c2ccccc2)c1 CHEMBL2024126 Ki(app) 887.8 nM
CCNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCCNC(=O)c1ccccc1)c1ccccc1 CHEMBL208346 IC50 892.0 nM
N[C@@H](CSC1(c2cccc3ccccc23)c2ccccc2-c2ccccc21)C(=O)O CHEMBL412312 Ki app 900.0 nM
Cc1ccc2[nH]c3c(c2c1)CCN(C(=O)C1CCCN(C)C1)C3c1cccc(O)c1 CHEMBL594459 IC50 900.0 nM
CNC(=O)N1N=C(c2cc(F)ccc2F)CC1(CO)c1ccccc1 CHEMBL206967 IC50 903.0 nM
FS(F)(F)(F)(F)c1ccc2c(c1)[C@H]1OCCC[C@H]1[C@H](c1ccccc1)N2 CHEMBL1089058 IC50 910.0 nM
O=C1CCc2cc(Nc3cccc(C(F)(F)F)c3)c(F)cc2N1 CHEMBL3289008 IC50 920.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C(C)C)cc1 CHEMBL1829408 IC50 940.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1ccncc1 CHEMBL2043394 IC50 942.2 nM
FC(F)(F)c1ccc2[nH]c3ccccc3c2c1 CHEMBL1170444 IC50 950.0 nM
CC(=O)NC1=NN(C(C)=O)C(C)(c2ccc(Cl)s2)S1 CHEMBL1391655 IC50 950.0 nM
CC1=C(C(=O)Nc2ccc(F)c(Cl)c2)C(c2ccco2)n2c(nc3ccccc32)N1 CHEMBL1277383 IC50 960.0 nM
Cc1ccc(C(=O)N(CCC(N)=O)C(c2nn3c(Cl)ccc3c(=O)n2Cc2ccccc2)C2CC2)cc1 CHEMBL380186 IC50 980.0 nM
CCC(c1nc2ccsc2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)nc1 CHEMBL1829416 IC50 980.0 nM
NCCSC(c1ccccc1)(c1ccccc1)c1cccc(C(=O)O)c1 CHEMBL2024123 Ki(app) 990.6 nM