O=C(Nc1cccc(N2CCC(F)(F)CC2)c1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL4776977 IC50 12.0 nM
O=C(Nc1cccc(OCCC(F)(F)F)n1)c1ccc(S(=O)(=O)NCCO)cc1N1CCC2(CC1)CC2 CHEMBL4755023 IC50 12.0 nM
Cc1ccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc1N1CCOCC1 CHEMBL4784192 IC50 12.0 nM
Cc1cc(NC(=O)c2cnc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5070813 IC50 13.0 nM
Cc1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL4777623 IC50 14.0 nM
C[C@@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(OCCC(F)(F)F)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL4752657 IC50 14.0 nM
Cc1cc(NC(=O)c2ncc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5075318 IC50 15.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)NCCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL4777759 IC50 16.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(OCCC(F)(F)F)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL4746340 IC50 16.0 nM
O=C(Nc1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2)c1cccc(N2CCC(F)(F)CC2)n1 CHEMBL5081181 IC50 16.0 nM
O=C(Nc1cncc(N2CCC(F)(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5094304 IC50 16.0 nM
N=[S@@](=O)(c1ccc(C(=O)Nc2cccc(OCCC(F)(F)F)n2)c(N2CCC3(CC2)CC3)c1)C1CC1 CHEMBL5091710 IC50 16.0 nM
O=C(Nc1ccnc(N2CCC(F)(F)CC2)c1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL4750775 IC50 17.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(C2CCC(F)(F)CC2)n1 CHEMBL4779888 IC50 17.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5087614 IC50 17.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5075165 IC50 17.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3ccc(NS(=O)(=O)[C@@H](C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL4751673 IC50 17.4 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC3(CC3)C2)n1 CHEMBL4776120 IC50 17.6 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OC2CCC2)n1 CHEMBL4743241 IC50 18.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(NC(C)(C)CO)n1 CHEMBL4740783 IC50 18.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5092103 IC50 18.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5072943 IC50 18.0 nM
O=C(Nc1cccc(OCC(O)C(F)(F)F)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5078662 IC50 18.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(OCC4CC4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5087385 IC50 19.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC[C@@](C)(F)C2)n1 CHEMBL5094252 IC50 20.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2C[C@H]3C[C@H]3C2)n1 CHEMBL5069425 IC50 20.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)CC2)n1 CHEMBL5093636 IC50 20.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5079933 IC50 20.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2ccnc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5079028 IC50 21.0 nM
N=[S@](=O)(c1ccc(C(=O)Nc2cccc(OCCC(F)(F)F)n2)c(N2CCC3(CC2)CC3)c1)C1CC1 CHEMBL5093289 IC50 22.0 nM
O=C(Nc1ccnc(N2CCC(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5080068 IC50 22.0 nM
O=C(Nc1ccnc(N2CCC(F)(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5086712 IC50 22.0 nM
O=C(Nc1ccnc(N2CCC(F)(F)CC2)c1F)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5081961 IC50 22.0 nM
O=C(Nc1cccc(N2CCC(F)(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5069902 IC50 23.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5085000 IC50 23.0 nM
O=C(Nc1ccnc(N2CC(F)(F)C2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5081092 IC50 23.0 nM
O=C(Nc1ccnc(N2CCC(F)(F)CC2)c1)c1ccc(S(=O)(=O)NCCO)cc1N1CCC2(CC1)CC2 CHEMBL5082550 IC50 23.0 nM
O=C(Nc1ccnc(N2CCC(F)(F)CC2)n1)c1ccc(S(=O)(=O)NCCO)cc1N1CCC2(CC1)CC2 CHEMBL5081140 IC50 23.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5082968 IC50 24.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CCF)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5081834 IC50 24.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CCO[C@@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5087332 IC50 24.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OCCC(F)(F)F)c1 CHEMBL5080425 IC50 24.0 nM
O=C(Nc1cccc(OCCC(F)(F)F)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5071190 IC50 25.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3COC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5089737 IC50 25.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CC(F)(F)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5094825 IC50 25.0 nM
N#Cc1ccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc1N1CCC(F)(F)CC1 CHEMBL5077314 IC50 25.0 nM
Cc1cc(Nc2nncc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)c1 CHEMBL5091082 IC50 25.0 nM
CC(C)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL4757053 IC50 26.0 nM
O=C(Nc1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2)c1cccc(N2CCCCC2)c1 CHEMBL4759372 IC50 26.0 nM
O=C(Nc1cccc(N2CCCCC2)c1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5085172 IC50 26.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL4743666 IC50 27.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5080453 IC50 27.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(C(C)C)n1 CHEMBL5079909 IC50 27.0 nM
O=C(Nc1ccnc(OCCC(F)(F)F)n1)c1ccc(S(=O)(=O)NCCO)cc1N1CCC2(CC1)CC2 CHEMBL5090672 IC50 27.0 nM
O=C(Nc1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2)c1ccnc(N2CCC(F)(F)CC2)c1 CHEMBL5075286 IC50 27.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3ccc(NS(=O)(=O)[C@H](C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5094909 IC50 28.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5085003 IC50 28.0 nM
O=C(Nc1cccc(N2CCC(F)(F)CC2)c1F)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL4765048 IC50 29.0 nM
CNS(=O)(=O)c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL4786845 IC50 29.0 nM
CC1(NS(=O)(=O)c2ccc(C(=O)Nc3ccnc(N4CCC(F)(F)CC4)c3)c(N3CCC4(CC3)CC4)c2)COC1 CHEMBL5093814 IC50 29.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5085449 IC50 30.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5083532 IC50 30.0 nM
CC(O)CCOc1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)n1 CHEMBL5084727 IC50 31.0 nM
C[C@@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2ccnc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5081444 IC50 31.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5084317 IC50 31.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NCCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5080216 IC50 32.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5070826 IC50 32.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(OCCC(F)(F)F)n1 CHEMBL5087262 IC50 32.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5079938 IC50 32.0 nM
COCCS(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)nc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5093393 IC50 32.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)C2)n1 CHEMBL5090562 IC50 32.0 nM
O=C(Nc1cccc(C2(C(F)(F)F)N=N2)c1)c1ccc(NS(=O)(=O)CCO)nc1N1CCC2(CC1)CC2 CHEMBL5289941 IC50 32.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCc5cc(Cl)ccc54)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5094422 IC50 33.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CC(F)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5083260 IC50 33.0 nM
C[C@@H]1CN(c2nc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)ccc2F)CCO1 CHEMBL5080556 IC50 33.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)C2)n1 CHEMBL5076026 IC50 33.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@@H]3C[C@@H]32)n1 CHEMBL5083227 IC50 33.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC3CC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5070081 IC50 33.0 nM
CC(C)S(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5083256 IC50 34.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCCCC4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5093536 IC50 34.0 nM
CCS(=O)(=O)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5086834 IC50 34.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)cc(N2CCC(F)(F)CC2)c1 CHEMBL5079627 IC50 34.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC3C[C@]3(O)C2)n1 CHEMBL5073188 IC50 34.0 nM
Cc1cc(NC(=O)c2cc(F)c(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5093190 IC50 34.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5086485 IC50 34.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC[C@H]3C[C@H]3C2)n1 CHEMBL5070583 IC50 35.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@@H](C)C2)n1 CHEMBL5084594 IC50 35.0 nM
CC[S@](=N)(=O)c1ccc(C(=O)Nc2cc(C)nc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5077277 IC50 35.0 nM
O=C(Nc1cccc(N2CCOCC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5092654 IC50 36.0 nM
C[C@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)[C@@H](C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077881 IC50 36.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5093712 IC50 36.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NCCO)nc1N1CCC2(CCC2)CC1 CHEMBL5089377 IC50 36.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5086677 IC50 37.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)[C@H](C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5070556 IC50 37.0 nM
Cc1cc(NC(=O)c2ccc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5081902 IC50 37.0 nM
C[C@H]1CN(c2nccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5083303 IC50 37.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5080992 IC50 37.3 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)C4COC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5081264 IC50 38.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCCC(F)(F)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5086892 IC50 38.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5092861 IC50 38.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5075991 IC50 38.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC2(CO)CC2)nc1N1CCC2(CCC2)CC1 CHEMBL5081958 IC50 38.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)cc(N2CCC(F)(F)CC2)n1 CHEMBL5091303 IC50 38.4 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(C)(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5086757 IC50 39.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5078657 IC50 39.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5087542 IC50 39.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CC3(O)COC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5092209 IC50 39.0 nM
Cc1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5070134 IC50 39.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5083372 IC50 39.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC2(CO)CC2)nc1N1CCC2(CC1)CC2 CHEMBL5081138 IC50 39.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC2(CO)COC2)nc1N1CCC2(CC1)CC2 CHEMBL5069662 IC50 39.0 nM
CC(CO)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5094366 IC50 39.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(N)(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL5084024 IC50 40.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3COC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5087263 IC50 40.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C3CNC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5090640 IC50 40.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(CO)CO)nc2N2CCC3(CC2)CC3)cc1S(=O)(=O)C1CCCC1 CHEMBL5075099 IC50 40.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5081684 IC50 41.0 nM
C[C@@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5075980 IC50 41.0 nM
Cc1ccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc1N1CCC(F)(F)CC1 CHEMBL5079069 IC50 41.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(C2CCC(F)(F)CC2)c1 CHEMBL5090729 IC50 41.0 nM
C[C@@H]1CN(c2cc(C#N)cc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5075895 IC50 41.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)CC2)n1 CHEMBL5094175 IC50 41.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@@](C)(F)C2)n1 CHEMBL5091189 IC50 41.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5070961 IC50 41.0 nM
Cc1cc(NC(=O)c2ccc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5091732 IC50 42.0 nM
C[C@@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5075507 IC50 42.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CF)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5090886 IC50 42.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H]3CCOC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5083730 IC50 42.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NCCO)cc2N2CCC3(CC2)CC3)nc(OCCC(F)(F)F)n1 CHEMBL5094355 IC50 42.0 nM
N=S(=O)(c1ccc(C(=O)Nc2ccnc(N3CCC(F)(F)CC3)c2)c(N2CCC3(CC2)CC3)c1)C1CC1 CHEMBL5079828 IC50 42.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NCC2(O)CC2)nc1N1CCC2(CC1)CC2 CHEMBL5080025 IC50 42.0 nM
C[C@@H](CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5082827 IC50 42.0 nM
C[C@H](CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5087600 IC50 42.0 nM
CC(C)CS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5082574 IC50 42.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)NC4(C)COC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5079126 IC50 43.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([S@@](=N)(=O)C4CC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077082 IC50 43.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)NCCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5075667 IC50 43.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@H](C#N)C2)n1 CHEMBL5082636 IC50 43.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC2COC2)nc1N1CCC2(CC1)CC2 CHEMBL5088847 IC50 43.0 nM
CNS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5090559 IC50 44.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC(F)CC4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5092300 IC50 44.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)N3CCC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5084653 IC50 44.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC(F)(F)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5090138 IC50 45.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(C2CC(F)(F)C2)c1 CHEMBL5081184 IC50 45.0 nM
O=C(Nc1cccc(OC(F)F)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5091135 IC50 45.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc3c2OCCC3)c(N2CCC3(CC2)CC3)c1 CHEMBL5075760 IC50 45.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CCCS3(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL5078825 IC50 45.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCCC(F)(F)C2)n1 CHEMBL5091576 IC50 45.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)NC(C)(C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5086228 IC50 46.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC[C@@H](O)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5093464 IC50 46.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC(F)(F)CC4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5087105 IC50 46.0 nM
C[C@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077455 IC50 46.0 nM
CC(CO)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5088014 IC50 47.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5075312 IC50 47.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)CC2)n1 CHEMBL5092027 IC50 47.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NCCCO)nc1N1CCC2(CC1)CC2 CHEMBL5094013 IC50 47.0 nM
CC(C)(CCO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5074431 IC50 47.0 nM
C[C@@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CC(F)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5080780 IC50 47.2 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CC(F)(F)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5079659 IC50 48.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CF)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5090322 IC50 48.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)[C@@H](C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5079953 IC50 48.0 nM
Cc1cc(NC(=O)c2cnc(S(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5080126 IC50 48.0 nM
CC(CO)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC3CC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077534 IC50 48.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(O)C2)n1 CHEMBL5078333 IC50 48.3 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3COC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5089989 IC50 48.9 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C(F)F)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5085686 IC50 49.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@@H](C)C2)c1 CHEMBL5085766 IC50 49.0 nM
Cc1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5087169 IC50 49.0 nM
Cc1cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)c1 CHEMBL5071420 IC50 49.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)(C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5094048 IC50 49.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(C2CC2)n1 CHEMBL5082594 IC50 49.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC5(CC5)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5075491 IC50 50.0 nM
CCS(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5078271 IC50 50.0 nM
CC1(COc2cccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)COC1 CHEMBL5091383 IC50 50.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)NC(C)(C)C)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5072492 IC50 51.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)C(C)(C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5072885 IC50 51.0 nM
CC(Oc1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)n1)C1CC1 CHEMBL5077629 IC50 51.0 nM
O=C(Nc1cccc(OCCC(F)F)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5077264 IC50 51.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(CS(C)(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL5082444 IC50 51.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5080961 IC50 51.0 nM
CCS(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)nc(N3CCC(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5080267 IC50 51.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N[C@@H]2CCOC2)nc1N1CCC2(CC1)CC2 CHEMBL5069883 IC50 51.0 nM
CC(c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)n1)S(C)(=O)=O CHEMBL5092913 IC50 51.2 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)NC3(C)CC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5086706 IC50 52.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CCC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5077127 IC50 52.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078741 IC50 52.0 nM
CC(O)(Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC3CC3)c2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F CHEMBL5079474 IC50 52.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5084085 IC50 52.5 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(CO)CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5079500 IC50 53.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(CO)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5073385 IC50 53.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NC(C)(CO)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5079129 IC50 53.4 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@@](C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5090915 IC50 53.4 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c(F)c(N2CCC(F)(F)CC2)n1 CHEMBL5086189 IC50 54.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC2(CO)CCC2)nc1N1CCC2(CC1)CC2 CHEMBL5083376 IC50 54.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC(CO)CO)nc1N1CCC2(CC1)CC2 CHEMBL5088406 IC50 54.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)N(C)C)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5075382 IC50 55.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)n1 CHEMBL5087048 IC50 55.0 nM
O=C(Nc1cccc(OCCC(F)(F)F)n1)c1ccc(S(=O)(=O)C2CNC2)cc1N1CCC2(CC1)CC2 CHEMBL5090340 IC50 55.0 nM
Cc1cc(NC(=O)c2cnc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5088011 IC50 55.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NC2(CCO)CC2)nc1N1CCC2(CC1)CC2 CHEMBL5094867 IC50 55.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1S(=O)(=O)C1CCCC1 CHEMBL5090438 IC50 55.0 nM
Cc1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5094659 IC50 55.1 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC[C@H](O)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5087471 IC50 56.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)C)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5089830 IC50 56.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3(C)COC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5087701 IC50 56.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC3(C)CCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5084958 IC50 56.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5080323 IC50 57.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4(CO)CC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5092666 IC50 57.0 nM
C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5075482 IC50 57.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5091432 IC50 57.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OC(C)C)n1 CHEMBL5083080 IC50 57.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5080194 IC50 57.0 nM
Cc1cc(NC(=O)c2ccc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5083516 IC50 57.0 nM
C[C@](O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F CHEMBL5078805 IC50 57.5 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CC(F)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5078747 IC50 58.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5087673 IC50 58.0 nM
O=C(Nc1ccnc(OCCC(F)(F)F)c1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5086081 IC50 58.0 nM
CC(C)(O)CNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077269 IC50 58.0 nM
Cc1ccc(NC(=O)c2ccc(NC3(CO)CC3)nc2N2CCC3(CC2)CC3)cc1S(=O)(=O)C1CCCC1 CHEMBL5077439 IC50 58.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CC3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5075378 IC50 59.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OCC(C)(C)O)c1 CHEMBL5082871 IC50 59.0 nM
Cc1cc(NC(=O)c2ccc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5075036 IC50 59.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC3CC32)n1 CHEMBL5073644 IC50 59.0 nM
CC(CO)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC(F)(F)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5078354 IC50 59.1 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)NC(C)(C)CO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5086447 IC50 60.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)NC3COC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5081201 IC50 60.0 nM
CCc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078726 IC50 60.0 nM
Cc1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)CC2)n1 CHEMBL5084372 IC50 60.0 nM
COCCNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5087207 IC50 60.0 nM
CC1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5084375 IC50 60.2 nM
CC(CO)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5094135 IC50 60.4 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL5085632 IC50 61.0 nM
Cc1ccnc2c(NC(=O)c3ccc(S(C)(=O)=O)cc3N3CCC4(CC3)CC4)cccc12 CHEMBL5088432 IC50 61.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5076091 IC50 61.0 nM
O=S(=O)(CCO)Nc1cc(N2CCC3(CC2)CC3)c2c(Nc3cccc(OCCC(F)(F)F)c3)ncnc2c1 CHEMBL5094682 IC50 61.0 nM
Cc1cc(NC(=O)c2ccc(NC(C)(CO)CO)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5083339 IC50 62.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4CCC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5092810 IC50 62.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CF)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5074931 IC50 62.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5071728 IC50 62.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CF)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)CC2)n1 CHEMBL5091618 IC50 62.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(CO)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5071320 IC50 62.2 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(C(C)(O)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5091428 IC50 62.5 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4COC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077711 IC50 63.0 nM
CN1CC(COc2cccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5089584 IC50 63.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)C(C)(C)C)cc2N2CCC3(CC2)CC3)c1 CHEMBL5083198 IC50 63.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(C)(F)CC2)n1 CHEMBL5080350 IC50 63.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NCCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5085537 IC50 63.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5077043 IC50 64.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(O)(C(F)(F)F)C2)n1 CHEMBL5087270 IC50 64.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5089869 IC50 64.0 nM
Cc1cc(NC(=O)c2ccc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5087026 IC50 64.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC[C@H](CO)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5086552 IC50 65.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(C(C)(C)O)n1 CHEMBL5082202 IC50 65.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(C)(O)CC2)n1 CHEMBL5080844 IC50 65.0 nM
C[C@H](O)CNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5074801 IC50 65.0 nM
CC(O)(Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F CHEMBL5082844 IC50 65.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(O)O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084915 IC50 65.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4(C)CC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5069705 IC50 66.0 nM
CC(C)(CO)Nc1cccc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)c1F CHEMBL5080015 IC50 66.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3cnc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5081351 IC50 66.7 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5076286 IC50 66.9 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)N4CCC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5090620 IC50 67.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C(C)(C)C)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5094010 IC50 67.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CC(F)F)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5083463 IC50 67.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)[C@H]3CCC(F)(F)C3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5082452 IC50 67.0 nM
CCS(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)nc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5088962 IC50 67.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(C#N)C2)n1 CHEMBL5088955 IC50 67.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)C)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5072052 IC50 68.0 nM
C[C@@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cccc(N3CC(F)(F)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5075554 IC50 68.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OCC(O)C(F)(F)F)c1 CHEMBL5088952 IC50 68.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3ccc(S(=O)(=O)NC4(C)COC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5086651 IC50 68.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@@H](C)O)cc2N2CCC3(CC2)CC3)nc(OCCC(F)(F)F)n1 CHEMBL5079433 IC50 68.0 nM
O=C(Nc1ccnc(N2CC(F)C2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5075603 IC50 68.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CCC3)CC2)cc1S(=O)(=O)C1CCCC1 CHEMBL5082280 IC50 68.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(CS(C)(=O)=O)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5081693 IC50 68.1 nM
O=C(Nc1cccc(N2CCOCC2)n1)c1ccc([C@@](O)(CO)C(F)(F)F)nc1N1CCC2(CC1)CC2 CHEMBL5088871 IC50 68.4 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(N)(=O)=O)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5075946 IC50 68.8 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(C)(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5088599 IC50 69.0 nM
Cc1cc(NC(=O)c2ccc(S(=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5084215 IC50 69.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC[C@H](O)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5086129 IC50 69.7 nM
O=C(Nc1cccc(N2CCOCC2)n1)c1ccc(C(O)(CO)C(F)(F)F)nc1N1CCC2(CC1)CC2 CHEMBL5091579 IC50 69.9 nM
CN(C)S(=O)(=O)c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5077023 IC50 70.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5089780 IC50 70.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OCCC(F)(F)F)n1 CHEMBL5079548 IC50 70.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5091294 IC50 70.0 nM
CC(C)(C)NS(=O)(=O)c1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)ccc1Cl CHEMBL5079699 IC50 70.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)c1 CHEMBL5080641 IC50 70.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5082451 IC50 70.5 nM
CC(C)(CO)Nc1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5076686 IC50 70.7 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5085588 IC50 71.0 nM
Cc1cc(NC(=O)c2ccc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5094151 IC50 71.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)c2)CCO1 CHEMBL5077285 IC50 71.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5084301 IC50 71.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@H](C)O)cc2N2CCC3(CC2)CC3)nc(OCCC(F)(F)F)n1 CHEMBL5075752 IC50 71.0 nM
Cc1cc(NC(=O)c2c(F)cc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5088807 IC50 71.0 nM
Cc1cc(NC(=O)c2ncc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5086169 IC50 71.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3(CO)CCC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5076819 IC50 71.0 nM
CC(O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F CHEMBL5090406 IC50 71.2 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCCC2)n1 CHEMBL5087681 IC50 71.6 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3C[C@H]4C[C@H]4C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5093120 IC50 71.9 nM
CCS(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)cc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5094911 IC50 72.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H]3CCOC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5085801 IC50 72.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCO[C@@H](CO)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5088989 IC50 73.0 nM
Cc1cc(Nc2ncnc3cc([S@](=N)(=O)C4CC4)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)c1 CHEMBL5083149 IC50 73.0 nM
Cc1cc(NC(=O)c2cc(F)c(NS(=O)(=O)[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5089510 IC50 73.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@H](C)O)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5088445 IC50 73.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5094581 IC50 74.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@@H](O)C2)n1 CHEMBL5091468 IC50 74.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cc(Cl)cc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5071063 IC50 74.3 nM
CCS(=O)(=O)Cc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5084689 IC50 75.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5080638 IC50 75.3 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)n1 CHEMBL5082226 IC50 76.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(N4CCCS4(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5087201 IC50 76.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(CO)CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5076597 IC50 76.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(CS(=O)(=O)C(C)(C)C)cc2N2CCC3(CC2)CC3)c1 CHEMBL5075224 IC50 76.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5091546 IC50 76.0 nM
C[C@@H](O)CNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5092875 IC50 76.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CC(F)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5094117 IC50 76.5 nM
O=C(Nc1cccc(N2CCOCC2)n1)c1ccc([C@](O)(CO)C(F)(F)F)nc1N1CCC2(CC1)CC2 CHEMBL5074830 IC50 76.9 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CCC3)CC2)c1 CHEMBL5076309 IC50 77.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5084063 IC50 77.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3(C)CCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5090073 IC50 77.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)C(C)(C)C)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5071297 IC50 78.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CCC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5088713 IC50 78.0 nM
CC(C)(O)COc1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5085132 IC50 78.0 nM
Cc1cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)nc(N2CCC(F)(F)CC2)c1 CHEMBL5074939 IC50 78.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3cc(F)c(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5089673 IC50 78.0 nM
CC[S@@](=N)(=O)c1ccc(C(=O)Nc2cc(C)nc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5070503 IC50 78.0 nM
Cc1cc(NC(=O)c2ccc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5084002 IC50 78.0 nM
CC1(NS(=O)(=O)c2cccc(NC(=O)c3ccc(NC(CO)CO)nc3N3CCC4(CC3)CC4)c2)CCC1 CHEMBL5075796 IC50 78.0 nM
O=C(Nc1cccc(N2CCC[C@@H](O)C2)n1)c1ccc(C(O)(CO)C(F)(F)F)nc1N1CCC2(CC1)CC2 CHEMBL5089334 IC50 78.1 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CF)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5092874 IC50 79.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H]3CCOC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5082434 IC50 79.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC3(CO)CC3)nc2N2CCC3(CC2)CC3)n1 CHEMBL5088296 IC50 79.3 nM
CNS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5089844 IC50 79.4 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(C(O)(CO)C(F)(F)F)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5094150 IC50 79.5 nM
CC1(NS(=O)(=O)c2ccc(C(=O)Nc3cccc(C(C)(C)O)n3)c(N3CCC4(CC3)CC4)c2)COC1 CHEMBL5093960 IC50 80.0 nM
CC(C)(O)COc1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)n1 CHEMBL5084311 IC50 80.0 nM
Cc1cc(NC(=O)c2ncc(NS(=O)(=O)CCO)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5094470 IC50 80.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3(CO)COC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5083345 IC50 80.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CCO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5089118 IC50 80.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C(C)(C)C)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5087537 IC50 80.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)NC3CCCC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5279604 IC50 80.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC[C@@H](O)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5075464 IC50 80.4 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCO[C@H](CO)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5092699 IC50 81.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3COC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5075849 IC50 81.0 nM
O=C(Nc1cccc(OCCC(O)C(F)(F)F)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5089940 IC50 81.0 nM
Cc1cc(NC(=O)c2ccc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5086501 IC50 81.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NCCCO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5083731 IC50 81.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5083562 IC50 82.0 nM
Cc1cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)n1 CHEMBL5075959 IC50 82.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCCCC2)n1 CHEMBL5093443 IC50 82.0 nM
C[C@H]1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5093291 IC50 82.1 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([C@](C)(O)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5091926 IC50 82.2 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(C3=CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5079523 IC50 82.9 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@@H](C)O)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5080897 IC50 83.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ncc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5078883 IC50 83.4 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC(F)(F)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5092360 IC50 83.4 nM
CC(C)(O)CCOc1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)n1 CHEMBL5087279 IC50 84.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)cc(OCCC(F)(F)F)n1 CHEMBL5080939 IC50 84.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3COC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5075568 IC50 84.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5074280 IC50 84.4 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(CS(C)(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5080615 IC50 85.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([S@](=N)(=O)C4CC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5076002 IC50 85.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CC3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5091894 IC50 85.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC[C@@H](CO)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5087184 IC50 86.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCCC(C#N)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5082220 IC50 86.0 nM
CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](CO)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5092434 IC50 86.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5093345 IC50 86.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3ccc(NS(=O)(=O)C[C@@H](C)O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5093815 IC50 86.0 nM
C[C@@H]1CN(c2cc(C3CC3)cc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5094416 IC50 87.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@@](C)(O)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5092845 IC50 87.3 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(CO)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5079450 IC50 87.8 nM
C[C@@](O)(c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F CHEMBL5089475 IC50 88.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NC(CO)(CO)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5090731 IC50 88.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C3(O)COC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5076007 IC50 88.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(C#N)CC2)n1 CHEMBL5081666 IC50 88.0 nM
Cc1cc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5092054 IC50 88.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([C@@](C)(O)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5093239 IC50 88.7 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(C(C)(C)O)c1 CHEMBL5078840 IC50 89.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H](CO)CF)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5084838 IC50 89.0 nM
C[C@@H]1CN(c2nc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)ccc2F)CCO1 CHEMBL5094286 IC50 89.1 nM
C[C@H]1CCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5069438 IC50 89.3 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(C)(O)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5079541 IC50 89.3 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4(F)CC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5075854 IC50 90.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCC(F)(F)CC2)c1)c1cccnc1N1CCC2(CCC2)CC1 CHEMBL5078310 IC50 90.0 nM
CC(C)(C)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5079211 IC50 90.0 nM
C[C@H](NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(CO)CO)nc2N2CCC3(CC2)CC3)c1)C(F)(F)F CHEMBL5287302 IC50 90.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5091994 IC50 90.4 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3C[C@@H]4C[C@H]3CO4)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5078436 IC50 90.5 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC(C#N)CC4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5082132 IC50 91.0 nM
Cc1cc(NC(=O)c2cc(F)c(NS(=O)(=O)[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5081509 IC50 91.0 nM
Cc1cc(NC(=O)c2ncc(S(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5086799 IC50 91.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(C)(=O)=O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5070127 IC50 91.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@@](C)(O)CO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5086672 IC50 92.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@@H](C#N)C2)n1 CHEMBL5080127 IC50 92.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)n1)c1ccc(NCCO)cc1N1CCC2(CC1)CC2 CHEMBL5288088 IC50 92.0 nM
Cc1cc(NC(=O)c2cc(Cl)c(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5083375 IC50 92.2 nM
C[C@@H]1CN(c2cc(C(F)(F)F)cc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5089897 IC50 93.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(C(F)(F)F)C2)n1 CHEMBL5093014 IC50 93.0 nM
CS(=O)(=O)Cc1ccc(C(=O)Nc2cccc(N3CCC[C@@H](O)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5089166 IC50 94.0 nM
CC(C)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL5086943 IC50 94.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5090985 IC50 94.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)[C@@H]3COC[C@H]3O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5079823 IC50 94.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3(CO)CC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5090269 IC50 94.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5070126 IC50 95.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCOC3(CC3)C2)n1 CHEMBL5086775 IC50 95.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2[C@H](C)COC[C@@H]2C)n1 CHEMBL5088999 IC50 95.0 nM
CC1(C)CCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5070473 IC50 95.3 nM
CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCC[C@H](O)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5077186 IC50 96.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@@H](CO)CF)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5070770 IC50 96.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NS(C)(=O)=O)nc2N2CCC3(CC2)CC3)n1 CHEMBL5287177 IC50 96.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)[C@H]3COC[C@@H]3O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5093138 IC50 97.0 nM
CCNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CCC3)CC2)n1 CHEMBL5093776 IC50 97.0 nM
C[C@@H]1COCCN1c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5079730 IC50 98.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(N4CCS4(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5069950 IC50 98.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)(C)C)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5089318 IC50 98.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@H]3C[C@@H](O)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5077531 IC50 98.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(CO)CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5085553 IC50 99.0 nM
C[C@H]1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C[C@H](C)O1 CHEMBL5075236 IC50 99.7 nM
CS(=O)(=O)Cc1ccc(C(=O)Nc2cccc(N3CCC[C@@H](O)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5094421 IC50 100.6 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@@](O)(CO)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5075441 IC50 100.9 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)c2F)CCO1 CHEMBL5090126 IC50 101.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)NC(C)(C)C)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5086780 IC50 102.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5076721 IC50 103.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5088087 IC50 103.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5093851 IC50 103.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(CO)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5081680 IC50 103.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5093594 IC50 103.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@H]3COC[C@@H]3O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5076506 IC50 103.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(CS(C)(=O)=O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5075442 IC50 103.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCC(F)(F)CC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5094090 IC50 104.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3C[C@H]4C[C@@H]3CO4)nc2N2CCC3(CC2)CC3)c1 CHEMBL5074006 IC50 104.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@](C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5085359 IC50 104.9 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([C@](O)(CO)C(F)(F)F)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5079506 IC50 105.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@H](O)C2)n1 CHEMBL5086591 IC50 105.0 nM
Cc1cc(NC(=O)c2ncc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5081899 IC50 105.0 nM
CC1(NS(=O)(=O)c2cccc(NC(=O)c3ccc(NC4(CO)CC4)nc3N3CCC4(CC3)CC4)c2)CCC1 CHEMBL5078992 IC50 105.0 nM
Cc1cc(NC(=O)c2ncc(NC(O)C(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5081388 IC50 105.6 nM
O=C(Nc1cccc(S(=O)(=O)N2CCCCC2)n1)c1ncc(NC2(CO)CC2)nc1N1CCC2(CC1)CC2 CHEMBL5093492 IC50 106.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C(F)(F)F)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5078144 IC50 106.0 nM
Cc1cc(NC(=O)c2ccc(CS(C)(=O)=O)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5083533 IC50 106.8 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5070299 IC50 107.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@@H]3CCC[C@H]3O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084937 IC50 107.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)C(C)(C)C(F)(F)F)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5093050 IC50 108.0 nM
CCS(=O)(=O)c1ccc(C(=O)Nc2cc(C)nc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5083960 IC50 108.0 nM
CC(C)(C)NS(=O)(=O)c1cc(F)cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5076264 IC50 108.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@](C)(O)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5082127 IC50 108.9 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CCC3)CC2)nc(N2CCC(F)(F)CC2)n1 CHEMBL5092912 IC50 109.0 nM
CC(C)(O)C(C)(C)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5083780 IC50 109.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(CO)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5086214 IC50 109.0 nM
C[C@H]1CN(c2cccc(NC(=O)c3ncc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C[C@H](C)O1 CHEMBL5076653 IC50 109.5 nM
CC1(C)CC(=O)N(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5090851 IC50 110.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)CC(C)(C)O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5090202 IC50 110.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CCC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5093053 IC50 110.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCO[C@H](CO)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5091248 IC50 110.5 nM
CC1(C)CC(=O)N(c2cccc(NC(=O)c3ncc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5083587 IC50 111.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CC(C)(C)O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077118 IC50 111.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)[C@@H]3CCC(F)(F)C3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5074183 IC50 111.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cc(Cl)cc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5092938 IC50 111.5 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@@H](C)O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5086632 IC50 112.0 nM
COc1cc(C(=O)Nc2cc(C)nc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)cc1NS(=O)(=O)CCO CHEMBL5080004 IC50 114.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccncc2N2CCC3(CC2)CC3)c1 CHEMBL5093113 IC50 114.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCCC(O)(CO)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5075607 IC50 114.4 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC(C)(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCC[C@@H](O)C2)c1 CHEMBL5086630 IC50 115.0 nM
CC(O)COc1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)n1 CHEMBL5072499 IC50 115.0 nM
CC(C)(CO)Nc1cccc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5085207 IC50 115.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5077656 IC50 115.0 nM
C[C@H](O)CS(=O)(=O)Nc1ccc(C(=O)Nc2ccnc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5080601 IC50 115.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N[C@H]2CCOC2)nc1N1CCC2(CC1)CC2 CHEMBL5075791 IC50 115.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@](O)(CO)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5075662 IC50 115.5 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([C@@](O)(CO)C(F)(F)F)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5082378 IC50 115.5 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@@H]3CC[C@H](O)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5077956 IC50 116.0 nM
CC(C)(C)NS(=O)(=O)c1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)ccc1F CHEMBL5094522 IC50 116.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cc(C#N)cc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5080491 IC50 116.2 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(O[C@@H]2CCOC2)n1 CHEMBL5086581 IC50 117.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5087712 IC50 118.0 nM
CCCC1CCN(c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)CC1 CHEMBL5091235 IC50 118.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CCC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084278 IC50 118.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N2CC(O)C2)nc1N1CCC2(CC1)CC2 CHEMBL5074677 IC50 118.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5082264 IC50 119.0 nM
Cc1cc(NC(=O)c2ccc(C(N)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5077157 IC50 119.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(O)(CO)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5086534 IC50 120.0 nM
CCC(CO)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5084651 IC50 120.0 nM
Cc1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5077108 IC50 120.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1S(=O)(=O)NC(C)(C)C CHEMBL5072390 IC50 121.0 nM
C[C@H]1CCN(c2cccc(NC(=O)c3ncc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5089962 IC50 122.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(CO)CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5090282 IC50 122.0 nM
CCS(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)nc(N3CCC(F)(F)CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5083178 IC50 122.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C(C)(C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5077725 IC50 122.0 nM
Cc1cc(NC(=O)c2ncc(NC(C)(C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5075334 IC50 122.0 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5094454 IC50 122.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOC(C(F)(F)F)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5094711 IC50 122.9 nM
Cn1ccnc1-c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5088731 IC50 124.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(=O)NCCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5085026 IC50 124.0 nM
CC(C)(O)c1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5083879 IC50 125.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CC3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5091571 IC50 125.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CCC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5082235 IC50 127.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC(C)(C)CC2)nc(N2CCC(F)(F)CC2)n1 CHEMBL5080201 IC50 127.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)N[C@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078423 IC50 127.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC[C@H]4CC[C@@H]3O4)nc2N2CCC3(CC2)CC3)c1 CHEMBL5089529 IC50 127.0 nM
CC(C)(O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)n1 CHEMBL5075531 IC50 128.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC23COC3)n1 CHEMBL5077511 IC50 128.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5071931 IC50 128.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CCCC3)CC2)c1 CHEMBL5076087 IC50 129.0 nM
Cc1cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)nc(N2CCC(F)(F)CC2)n1 CHEMBL5084616 IC50 129.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C3(C)COC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5090284 IC50 130.0 nM
C[C@@H]1CN(c2cc(F)cc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)c2)CCO1 CHEMBL5081856 IC50 131.0 nM
CNC(=O)c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5090008 IC50 132.0 nM
CCC1CCN(c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)CC1 CHEMBL5078307 IC50 133.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NCCO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5075762 IC50 133.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCCC3(C)CO)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5084428 IC50 134.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)(C)C)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)c1 CHEMBL5090625 IC50 134.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NCCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5077260 IC50 134.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1cccnc1N1CCC2(CCC2)CC1 CHEMBL5074723 IC50 134.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@@H]3CCOC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084270 IC50 134.0 nM
COc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5075537 IC50 134.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CC(F)(F)F)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077436 IC50 135.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5085483 IC50 135.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2-c2ccc(Cl)cc2)c1 CHEMBL5093912 IC50 135.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)[C@H]3CCOC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5094854 IC50 135.0 nM
Cc1cnc(-c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)c2)o1 CHEMBL5073431 IC50 135.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5083980 IC50 136.0 nM
CC1(O)CCCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5094157 IC50 136.5 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cc(C#N)cc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5083462 IC50 138.0 nM
O=C(NCCO)c1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5092478 IC50 139.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC3(CO)CC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5092642 IC50 139.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)cc2N2CCC3(CC2)CC3)n1 CHEMBL5278809 IC50 140.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)C4(C)COC4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5070896 IC50 141.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@](C)(O)CO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5091017 IC50 141.0 nM
CC(C)c1ccc(-c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)cc1 CHEMBL5083895 IC50 141.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@H](C)O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078364 IC50 141.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N2CC(CO)C2)nc1N1CCC2(CC1)CC2 CHEMBL5081794 IC50 141.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N2CCC2)nc1N1CCC2(CCC2)CC1 CHEMBL5078000 IC50 141.0 nM
N=[S@](=O)(c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1)C1CCC1 CHEMBL5091835 IC50 142.0 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CCO)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5079638 IC50 142.3 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCC[C@@H](O)C2)c1 CHEMBL5083162 IC50 142.5 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC[C@@](C)(O)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5086765 IC50 143.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ncc(NC2(CO)CC2)nc1N1CCC2(CC1)CC2 CHEMBL5085570 IC50 143.0 nM
CC1(NS(=O)(=O)c2ccc(C(=O)Nc3ccnc(C(C)(C)O)n3)c(N3CCC4(CC3)CC4)c2)COC1 CHEMBL5085522 IC50 143.0 nM
CC(C)(C)NS(=O)(=O)c1cc(Br)cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5081461 IC50 143.0 nM
Cc1cc(NC(=O)c2cc(C)c(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5081922 IC50 144.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(O)CC2)n1 CHEMBL5080377 IC50 144.0 nM
Cc1cc(NC(=O)c2ccc(CS(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5077040 IC50 145.0 nM
CCc1ccc(-c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)cc1 CHEMBL5091314 IC50 146.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC3(CC2)CC3)n1 CHEMBL5084654 IC50 146.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)N[C@@H](C)CO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5090442 IC50 147.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)cc(N2CCO[C@H](C)C2)n1 CHEMBL5085946 IC50 148.0 nM
CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(NC3(CO)COC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5087723 IC50 149.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(C)(=O)=O)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5078169 IC50 149.5 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCOC(C)(C)C2)n1 CHEMBL5093597 IC50 150.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5079694 IC50 151.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@H](C)O)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5076469 IC50 151.0 nM
C[C@@H]1CN(c2cc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)ccn2)CCO1 CHEMBL5076993 IC50 151.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([S@@](C)(=N)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5074525 IC50 154.0 nM
COC(=O)C(F)(C(=O)OC)c1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5081477 IC50 156.0 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(NC(C)(C)CO)c1 CHEMBL5081863 IC50 157.0 nM
Cc1cc(NC(=O)c2cc(F)c(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5076269 IC50 158.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(C(F)(CO)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5087881 IC50 158.5 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC(C#N)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5077546 IC50 159.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CC4(COC4)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5088276 IC50 159.2 nM
N=[S@@](=O)(c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1)C1CCC1 CHEMBL5085744 IC50 160.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCC(F)CC2)c1)c1cccnc1N1CCC2(CCC2)CC1 CHEMBL5083989 IC50 160.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@H]3CCC[C@H]3O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5088849 IC50 160.0 nM
CCC1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5069852 IC50 160.5 nM
C[C@@H]1CN(c2nc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)cc(C(C)(C)O)n2)CCO1 CHEMBL5077245 IC50 161.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N[C@@H]2CC[C@H]2O)nc1N1CCC2(CC1)CC2 CHEMBL5075352 IC50 161.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C[C@@H](C)O)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5091493 IC50 162.0 nM
COc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1S(=O)(=O)NC(C)(C)C CHEMBL5079635 IC50 162.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCS(=O)(=O)CC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5093266 IC50 162.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)nc(C(C)(C)O)c1 CHEMBL5082256 IC50 163.0 nM
CCC(C)C1CCN(c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)CC1 CHEMBL5091436 IC50 163.0 nM
Cc1cc(NC(=O)c2ccc(S(=N)(=O)C3COC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5087671 IC50 163.0 nM
Cc1cc(NC(=O)c2ccc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5076776 IC50 165.0 nM
Cc1cncc(-c2cc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)ccc2C)c1 CHEMBL5078744 IC50 165.0 nM
CC(C)(O)CNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5276902 IC50 165.0 nM
CC(C)(C)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)n1 CHEMBL5076747 IC50 166.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3(CO)CC3)cc2N2CCC3(CC2)CC3)n1 CHEMBL5270982 IC50 166.0 nM
COC1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5075934 IC50 168.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2-c2ccc(C(F)(F)F)cc2)c1 CHEMBL5088817 IC50 168.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)nc(NC(C)(C)CO)n1 CHEMBL5083263 IC50 168.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(NCC2(O)CCC2)nc1N1CCC2(CC1)CC2 CHEMBL5089284 IC50 168.0 nM
CC1(O)CN(c2ccc(C(=O)Nc3cccc(S(=O)(=O)NC(C)(C)C)n3)c(N3CCC4(CC3)CC4)n2)C1 CHEMBL5093433 IC50 169.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CCO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5087094 IC50 169.5 nM
CC(C)(C)NS(=O)(=O)c1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(-c2ccco2)c1 CHEMBL5074968 IC50 170.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOC(C)(C)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5071802 IC50 172.0 nM
CC(C)(C)NS(=O)(=O)c1cc(F)cc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5089446 IC50 172.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(C(C)(C)O)C2)n1 CHEMBL5080904 IC50 172.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)C3(C)COC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5072142 IC50 173.0 nM
Cc1cc(NC(=O)c2ccc(NC3(CO)COC3)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5080318 IC50 173.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc([C@@](C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)c1 CHEMBL5078638 IC50 174.0 nM
CC1(S(=O)(=O)Nc2ccc(C(=O)Nc3cccc(N4CCC[C@](C)(O)C4)n3)c(N3CCC4(CC3)CC4)c2)CC1 CHEMBL5087965 IC50 175.0 nM
Cc1cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)cc(OCCC(F)(F)F)c1 CHEMBL5084214 IC50 175.0 nM
Cc1cc(NC(=O)c2ccc(S(=N)(=O)C(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5088400 IC50 175.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)c1 CHEMBL5081638 IC50 175.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(N3CCO[C@H](CO)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5086476 IC50 176.0 nM
C[C@@H]1CN(c2cc(NC(=O)c3ccc(NS(=O)(=O)CCO)cc3N3CCC4(CC3)CC4)ccc2F)CCO1 CHEMBL5080964 IC50 177.0 nM
CC1CCN(c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)CC1 CHEMBL5078667 IC50 177.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1F CHEMBL5092945 IC50 177.0 nM
Cc1cc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5080923 IC50 178.2 nM
CC(C)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)n1 CHEMBL5087952 IC50 179.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(C(F)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5092353 IC50 180.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc(C3CC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5093919 IC50 180.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(N3C[C@@H]4C[C@H]3CO4)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5089666 IC50 182.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([S@@](=N)(=O)C(C)(C)C)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5081381 IC50 182.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C3COC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078150 IC50 182.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC(S(C)(=O)=O)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5081847 IC50 182.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(OCCCC(F)(F)F)c1 CHEMBL5081307 IC50 184.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@H]3CC[C@H](O)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5094194 IC50 185.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CC3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)c1 CHEMBL5085318 IC50 186.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(NC(C)(C)CO)n1 CHEMBL5093395 IC50 186.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc(C3CC3)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5069863 IC50 187.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2[C@H](C)COC[C@H]2C)n1 CHEMBL5084160 IC50 187.0 nM
CC1(NS(=O)(=O)c2cccc(NC(=O)c3cccnc3N3CCC4(CC3)CC4)c2)CCC1 CHEMBL5080945 IC50 189.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC[C@@H](O)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5081615 IC50 189.0 nM
CC1(C)CCN(c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)CC1 CHEMBL5081382 IC50 190.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3C[C@H]4C[C@H]4C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5090288 IC50 191.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(OC(F)F)C2)n1 CHEMBL5072268 IC50 192.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC3C[C@]3(O)C2)n1 CHEMBL5077169 IC50 193.0 nM
CC(C)(C)[S@@](=N)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5075140 IC50 194.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)[C@@H]3CCC[C@H]3O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5087064 IC50 195.0 nM
Cc1cc(NC(=O)c2ccc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5079609 IC50 195.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(F)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5080133 IC50 196.0 nM
CC1(C)CCN(c2ccc(C(=O)Nc3cccc(S(=O)(=O)NC(C)(C)C)c3)c(N3CCC4(CC3)CC4)n2)C1 CHEMBL5087766 IC50 196.0 nM
CC1(O)CN(c2ccc(C(=O)Nc3cccc(S(=O)(=O)NC(C)(C)C)c3)c(N3CCC4(CC3)CC4)n2)C1 CHEMBL5092288 IC50 196.0 nM
CC(C)(CO)Nc1cccc(NC(=O)c2ccc(S(=O)(=O)NC3(C)COC3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5081032 IC50 198.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([S@](=N)(=O)C(C)(C)C)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5089344 IC50 199.0 nM
C[C@@H]1CN(c2cc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)ccc2F)CCO1 CHEMBL5079437 IC50 199.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc3ccoc23)c(N2CCC3(CC2)CC3)c1 CHEMBL5081239 IC50 200.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC[C@@H]4C[C@@H]43)nc2N2CCC3(CC2)CC3)c1 CHEMBL5094189 IC50 200.0 nM
CN(CCO)C(=O)c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5088288 IC50 201.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCCC3=O)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5081855 IC50 204.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)C3(C)CCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077490 IC50 204.0 nM
C[C@H]1COCCN1c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5078695 IC50 205.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC2)n1 CHEMBL5087444 IC50 205.0 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5074715 IC50 206.0 nM
Cc1cc(NC(=O)c2cnc([S@@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5073613 IC50 206.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C(F)(F)F)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5089621 IC50 207.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)C(C)(C)C(F)(F)F)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5089756 IC50 208.0 nM
C[C@@H]1CN(c2cc(F)cc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)c2)CCO1 CHEMBL5081641 IC50 208.0 nM
CC(C)(C)NS(=O)(=O)c1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(-c2ccoc2)c1 CHEMBL5073456 IC50 208.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)N4CC(C#N)C4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5086527 IC50 209.0 nM
Cc1ccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)cc1S(=O)(=O)N1CCCCC1 CHEMBL5069535 IC50 211.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC(F)(F)C3)c1 CHEMBL5087630 IC50 215.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N[C@H](C)CO)n1 CHEMBL5083987 IC50 216.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CC(O)CC3(C)C)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5069996 IC50 217.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCCCC2)c1)c1cccnc1N1CCC2(CCC2)CC1 CHEMBL5084353 IC50 217.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(S(=O)(=O)C(C)(C)C)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5082059 IC50 218.0 nM
Cc1cc(NC(=O)c2ccc(NC3(CO)COC3)nc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5079025 IC50 218.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC(C3CC3)CC2)c1 CHEMBL5081591 IC50 221.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3CCC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5094904 IC50 221.0 nM
COCC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5078561 IC50 222.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NC(C)(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5091855 IC50 222.0 nM
O=C(Nc1cc(C2CC2)nc(N2CCC(F)(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2 CHEMBL5079851 IC50 225.0 nM
Cc1coc(-c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)c2)n1 CHEMBL5083031 IC50 225.0 nM
Cc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5092540 IC50 230.0 nM
Cc1cc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL5085982 IC50 231.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC[C@H](O)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5094787 IC50 234.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5094332 IC50 234.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CCOCC3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5093010 IC50 238.0 nM
COC(=O)C(F)(C(=O)OC)c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077150 IC50 239.0 nM
CC(C)(CCO)Nc1ccc(C(=O)Nc2cccc(N3CCO[C@H](CO)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077452 IC50 239.0 nM
CC(C)(CO)Nc1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5087397 IC50 240.0 nM
C[C@@H]1CN(c2nccc(NC(=O)c3ccc(S(C)(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5088502 IC50 240.0 nM
CC(C)C1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5086987 IC50 242.0 nM
C[C@H]1CN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)[C@@H](C)CO1 CHEMBL5091273 IC50 243.0 nM
CC1(O)CCN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4(C)CC4)cc3N3CCC4(CC3)CC4)n2)CC1 CHEMBL5093789 IC50 243.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2[C@@H](C)COC[C@@H]2C)n1 CHEMBL5093749 IC50 245.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc3cccnc23)c(N2CCC3(CC2)CC3)c1 CHEMBL5081017 IC50 246.0 nM
Cc1cc(NC(=O)c2ccc(N3CCOCS3(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5091088 IC50 246.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1ncco1 CHEMBL5094526 IC50 246.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(C3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5087618 IC50 247.0 nM
C[C@@H]1CO[C@@H](C)CN1c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5088931 IC50 252.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccncc1N1CCC2(CC1)CC2 CHEMBL5086759 IC50 253.0 nM
CN(CCO)c1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5276935 IC50 253.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCC(F)CC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5089597 IC50 259.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N[C@@H]3CCOC[C@H]3O)nc2N2CCC3(CC2)CC3)c1 CHEMBL5093013 IC50 259.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(C(C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5077654 IC50 260.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5070068 IC50 260.0 nM
COc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5089948 IC50 261.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1N1CCOCC1 CHEMBL5092872 IC50 261.0 nM
Cc1cc(Nc2ncnc3cc([S@@](=N)(=O)C4CC4)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)c1 CHEMBL5092778 IC50 262.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5086922 IC50 262.0 nM
Cc1cc(NC(=O)c2cnc([S@](=N)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5079508 IC50 264.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1ccoc1 CHEMBL5093724 IC50 265.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(=O)NC(C)(C)CO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5087394 IC50 272.0 nM
Cc1cc(NC(=O)c2cnc(NS(=O)(=O)CCO)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5076230 IC50 272.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1ccco1 CHEMBL5083075 IC50 277.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cc(C3CC3)cc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5071727 IC50 278.0 nM
Cc1ccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)cc1S(=O)(=O)C1CCCC1 CHEMBL5087080 IC50 279.0 nM
CC(C)(CF)NS(=O)(=O)c1cccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)c1 CHEMBL5094888 IC50 279.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1N1CCCC1=O CHEMBL5084323 IC50 279.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CC(O)(C(F)(F)F)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5071056 IC50 280.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3([C@H](C)O)CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078127 IC50 281.0 nM
Cc1ccc(NC(=O)c2cccnc2N2CCC(C)(C)CC2)cc1S(=O)(=O)N1CCCCC1 CHEMBL5085682 IC50 282.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(F)(CO)CO)nc2N2CCC3(CC2)CC3)n1 CHEMBL5093003 IC50 283.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(C)(=O)=O)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5071897 IC50 284.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C3(C(F)(F)F)COC(C)(C)O3)nc2N2CCC3(CC2)CC3)n1 CHEMBL5082241 IC50 286.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)NCC(C)(C)O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5090311 IC50 286.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(N4CCNS4(=O)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5081365 IC50 287.0 nM
CC(O)(c1ccc(NC(=O)c2cccc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1)C(F)(F)F CHEMBL5081503 IC50 292.5 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC3CC(F)(F)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084295 IC50 294.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC(O)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5093898 IC50 294.5 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(OC2COC2)nc1N1CCC2(CC1)CC2 CHEMBL5075781 IC50 296.0 nM
CC(C)(CO)Nc1cccc(NC(=O)c2ccc(NS(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)c1F CHEMBL5094295 IC50 298.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CCC(F)(F)C3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5077409 IC50 302.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1ccccn1 CHEMBL5089823 IC50 303.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1cccnc1 CHEMBL5085641 IC50 306.0 nM
CC(C)(C)NC(=O)c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5090145 IC50 314.0 nM
CC(C)(O)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)n1 CHEMBL5094046 IC50 315.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(-c3ncco3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5085784 IC50 315.7 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NCc3ccccc3)nc2N2CCC3(CC2)CC3)c1 CHEMBL5070691 IC50 317.0 nM
CC(C)C1CCN(c2nc(NC(C)(C)CO)cnc2C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)CC1 CHEMBL5075620 IC50 319.0 nM
CC1(NS(=O)(=O)c2cccc(NC(=O)c3cccnc3N3CCC4(CC3)CC4)c2)CC1 CHEMBL5092550 IC50 320.0 nM
CC(C)(C)[S@](=N)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5077677 IC50 323.0 nM
O=C(Nc1cccc(S(=O)(=O)NC2CCC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5081746 IC50 323.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3([C@@H](C)O)CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5092576 IC50 324.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC(O)CC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077849 IC50 330.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC(F)(F)CC2)c1 CHEMBL5081828 IC50 342.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCCCC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5084032 IC50 342.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(N3CCCC3(C)C)nc2N2CCC3(CC2)CC3)c1 CHEMBL5092930 IC50 342.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1ccn[nH]1 CHEMBL5085782 IC50 342.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)CCC(F)(F)F)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5087250 IC50 343.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1nccs1 CHEMBL5090169 IC50 349.0 nM
Cc1cc(NC(=O)c2ccc(NC3(C)COC3)nc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5087469 IC50 355.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc([C@](C)(O)C(F)(F)F)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084888 IC50 356.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCC(O)C3(C)C)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5082510 IC50 357.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOC(CN)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5074945 IC50 357.0 nM
CC1(O)CCN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4(C)CC4)cc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5087892 IC50 359.0 nM
COc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)n2)c(N2CCC3(CC2)CC3)c1 CHEMBL5284647 IC50 360.0 nM
CC(C)(C)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)c1 CHEMBL5093122 IC50 362.0 nM
CC(C)(C)S(=N)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)n1 CHEMBL5087867 IC50 363.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCOC(C(C)(C)O)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5079173 IC50 365.0 nM
CC1(F)CCN(c2cccc(NC(=O)c3ccc(NS(=O)(=O)C4(C)CC4)cc3N3CCC4(CC3)CC4)n2)CC1 CHEMBL5076832 IC50 373.0 nM
Cc1ccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc1-c1ccncc1 CHEMBL5077565 IC50 386.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCCC(N)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5086338 IC50 388.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(NCCO)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077237 IC50 392.0 nM
O=C(Nc1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5080513 IC50 393.0 nM
Cc1cc(NC(=O)c2cc(NCCO)ncc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5078599 IC50 394.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CC(F)(F)C2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5079349 IC50 401.0 nM
COc1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5077202 IC50 401.5 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)nc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5078022 IC50 402.0 nM
Cc1cc(C)cc(Nc2ncnc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)c1 CHEMBL5088325 IC50 403.0 nM
CC(C)(O)CNc1cnc(C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5081120 IC50 406.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C3CN(C)C3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5082487 IC50 406.0 nM
COC1CCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5082049 IC50 407.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CC3(CCCCC3)C2)c1 CHEMBL5075413 IC50 410.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5084830 IC50 410.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(OCCC(C)(C)N)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5077678 IC50 411.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C(C)(C)C)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5079597 IC50 413.0 nM
Cc1noc(-c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)c2)n1 CHEMBL5084110 IC50 417.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc([S@](C)(=N)=O)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5076735 IC50 418.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2-c2ccc(F)cc2)c1 CHEMBL5069642 IC50 418.0 nM
C[S@@](=N)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5085500 IC50 429.0 nM
Cn1ccnc1-c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5084329 IC50 437.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=N)=O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5080538 IC50 438.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3cnc(NC(C)(C)CO)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5083759 IC50 440.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(NC[C@H](C)O)n1 CHEMBL5074557 IC50 451.0 nM
Cc1cc(NC(=O)c2ccc(NC3(C)COC3)nc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5082926 IC50 453.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC(C(F)(F)F)CC2)c1 CHEMBL5080912 IC50 455.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)N4CC(C)(C#N)C4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5080114 IC50 458.0 nM
O=C(Nc1cccc(S(=O)(=O)NC2CC(F)(F)C2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5082317 IC50 474.0 nM
C[S@](=N)(=O)c1cccc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)c1 CHEMBL5082095 IC50 488.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(N[C@@H](C)CO)n1 CHEMBL5080457 IC50 491.0 nM
O=C(Nc1cccc(S(=O)(=O)NC2CC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5083490 IC50 517.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCCCC2)c1)c1cn[nH]c1-c1ccc(Cl)cc1 CHEMBL5266739 IC50 520.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(N4CC(O)CC4(C)C)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5092960 IC50 523.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1F CHEMBL5079849 IC50 527.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(-c3ncco3)cc2N2CCC3(CC2)CC3)c1 CHEMBL5093616 IC50 534.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cc(C3CC3)cc(N3CCOCC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5093698 IC50 540.0 nM
Cc1cc(NC(=O)c2ccc(N3CC(O)CC3(C)C)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5070584 IC50 540.3 nM
Cn1nccc1-c1cccc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)c1 CHEMBL5087873 IC50 542.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(N3CCS(=O)(=O)CC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5076705 IC50 545.0 nM
CC1(C)CCN(c2ncccc2C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)CC1 CHEMBL5089677 IC50 553.0 nM
CC(C)(C)NS(=O)(=O)c1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(-c2cccnc2)c1 CHEMBL5084163 IC50 561.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(S(=O)(=O)N4CC(C)(C)C4)cc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5083261 IC50 566.0 nM
O=C(Nc1ccc(Br)c(S(=O)(=O)N2CCCC(F)(F)C2)c1)c1ccncc1N1CCC2(CC1)CC2 CHEMBL5075965 IC50 571.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(NC[C@@H](C)O)n1 CHEMBL5070048 IC50 580.0 nM
O=C(Nc1cccc(S(=O)(=O)N2CCC(F)(F)C2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5080331 IC50 581.0 nM
COC1CN(c2ccc(C(=O)Nc3cccc(S(=O)(=O)NC(C)(C)C)c3)c(N3CCC4(CC3)CC4)n2)C1 CHEMBL5082178 IC50 591.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCN(C(=O)OC(C)(C)C)CC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5093944 IC50 592.0 nM
Cn1nccc1-c1ccc(C(=O)Nc2cccc(S(=O)(=O)NC(C)(C)C)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5082842 IC50 601.0 nM
CN1CCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)CC1 CHEMBL5077295 IC50 604.0 nM
Cc1ccc(NC(=O)c2ccncc2N2CCC3(CC2)CC3)cc1S(=O)(=O)N1CCCC(F)(F)C1 CHEMBL5090650 IC50 606.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCCC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5076218 IC50 610.0 nM
CN(C1CCC1)S(=O)(=O)c1cccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)c1 CHEMBL5076375 IC50 610.0 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc3ccsc23)c(N2CCC3(CC2)CC3)c1 CHEMBL5069537 IC50 630.0 nM
CC(C)(C)NS(=O)(=O)c1cc(NC(=O)c2ccc(NC(C)(C)CO)nc2N2CCC3(CC2)CC3)cc(C2CC2)c1 CHEMBL5083325 IC50 633.0 nM
COCC(C)(C)Nc1ccc(C(=O)Nc2cccc(N3CCO[C@H](C)C3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5090636 IC50 636.3 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC3(COC3)C2)n1 CHEMBL5082690 IC50 640.0 nM
Cc1cc(NC(=O)c2ncc(NS(C)(=O)=O)nc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)c1 CHEMBL5077937 IC50 642.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(F)nc2N2CCC3(CC2)CC3)n1 CHEMBL5078066 IC50 643.0 nM
CCCC1CCN(c2ncccc2C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)CC1 CHEMBL5080977 IC50 656.0 nM
C[C@@H]1CN(c2cccc(NC(=O)c3ccc(N4C(=O)OCC4(C)C)nc3N3CCC4(CC3)CC4)n2)CCO1 CHEMBL5083585 IC50 663.0 nM
CN(C)CCNc1ccc(C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5077259 IC50 678.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccc(N2CCOCC2)nc1N1CCC2(CCC2)CC1 CHEMBL5082304 IC50 688.0 nM
Cc1cc(NC(=O)c2ccc(OCC(N)(CO)C(F)(F)F)nc2N2CCC3(CC2)CC3)nc(N2CCOCC2)c1 CHEMBL5075494 IC50 692.0 nM
CC(C)(CO)Nc1ccc(C(=O)Nc2cccc(N3CCN(C4CC4)CC3)n2)c(N2CCC3(CC2)CC3)n1 CHEMBL5080774 IC50 693.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC([C@H](C)O)C2)n1 CHEMBL5075542 IC50 704.0 nM
Cc1ccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)cc1S(=O)(=O)NC1CC1 CHEMBL5083693 IC50 712.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C3(C)CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5091774 IC50 713.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1cccnc1N1CCC2(CC1)CC(F)(F)C2 CHEMBL5090645 IC50 734.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccncc1N1CCC2(CC1)CC2(F)F CHEMBL5090427 IC50 735.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)N2CCCC(F)(F)C2)c1)c1ccncc1N1CCC2(CC1)CC2 CHEMBL5075242 IC50 735.0 nM
CC1(C)OCC(c2ccc(C(=O)Nc3cccc(N4CCOCC4)n3)c(N3CCC4(CC3)CC4)n2)(C(F)(F)F)O1 CHEMBL5084979 IC50 758.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1F)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5088798 IC50 760.0 nM
CC(C)(CO)Nc1cnc(C(=O)Nc2cccc(N3CCOCC3)c2)c(N2CCC3(CC2)CC3)n1 CHEMBL5088661 IC50 768.0 nM
CCCC1CCN(c2ncccc2C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)CC1 CHEMBL5077109 IC50 778.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CCC(C(C)(C)C)CC2)c1 CHEMBL5086340 IC50 788.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C2)n1 CHEMBL5084359 IC50 788.0 nM
O=C(Nc1cccc(S(=O)(=O)NC2CC2)c1)c1ccc(NC2(CO)CC2)nc1N1CCC2(CC1)CC2 CHEMBL5077365 IC50 800.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)CC(C)(C)O)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5074617 IC50 806.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(N3C(=O)OCC3(C)C)nc2N2CCC3(CC2)CC3)n1 CHEMBL5082415 IC50 817.0 nM
Cc1cc(NC(=O)c2ccc(S(=O)(=O)C3CC3)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1 CHEMBL5079132 IC50 826.0 nM
Cc1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)nc(NCCO)n1 CHEMBL5070350 IC50 849.0 nM
CCC1CCN(c2ncccc2C(=O)Nc2cccc(S(=O)(=O)C3CCCC3)c2)CC1 CHEMBL5075283 IC50 850.0 nM
O=C(Nc1cccnc1N1CCC2(CC1)CC2)c1cccc(N2CCOCC2)n1 CHEMBL5091942 IC50 860.5 nM
CS(=O)(=O)c1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)c(N2CCC3(CC2)CC3)c1 CHEMBL5091165 IC50 862.0 nM
O=C(Nc1cccc(S(=O)(=O)CC2CC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5084728 IC50 910.0 nM
Cc1cc(NC(=O)c2ccc(NC3COC3)nc2N2CCC3(CC2)CC3)nc(N2CCO[C@H](C)C2)n1 CHEMBL5074779 IC50 916.0 nM
O=C(Nc1cccc(S(=O)(=O)NC2CCCCC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5079740 IC50 918.0 nM
O=C(Nc1cccc(S(=O)(=O)C2CCC2)c1)c1cccnc1N1CCC2(CC1)CC2 CHEMBL5071454 IC50 923.0 nM
CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ncc(NC(C)(C)CO)nc2N2CC3(CCC3)C2)c1 CHEMBL5081429 IC50 931.0 nM
CC(C)NS(=O)(=O)c1cccc(NC(=O)c2cccnc2N2CCC3(CC2)CC3)c1 CHEMBL5080206 IC50 934.0 nM
Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(C)(O)C2)n1 CHEMBL5093216 IC50 935.0 nM
Cc1cc(Nc2ncnc3cc(S(C)(=O)=O)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)c1 CHEMBL5084781 IC50 940.0 nM
CN(C(=O)OC(C)(C)C)C1CCCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5088519 IC50 948.0 nM
Cc1cc(Nc2nc(C)nc3cc(NS(=O)(=O)CCO)cc(N4CCC5(CC4)CC5)c23)cc(N2CCC(F)(F)CC2)c1 CHEMBL5074619 IC50 955.0 nM
CCC1CCN(c2ncccc2C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)CC1 CHEMBL5087503 IC50 983.0 nM
CNC1CCCN(c2cccc(NC(=O)c3ccc(NC(C)(C)CO)nc3N3CCC4(CC3)CC4)n2)C1 CHEMBL5086348 IC50 999.0 nM