C[C@@H](Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4091152 Ki 0.05 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4070212 Ki 0.1 nM
O=C(O)c1cc(-c2cccc(Cl)c2F)ncn1 CHEMBL3407904 IC50 0.2 nM
O=C(O)c1cc(-c2ccc(F)c(F)c2)ncn1 CHEMBL3407905 IC50 0.2 nM
O=C(O)c1nccc(-c2ccc(F)c(F)c2)n1 CHEMBL3903832 IC50 0.2 nM
O=C(O)c1nccc(-c2cccc(Cl)c2F)n1 CHEMBL3931822 IC50 0.2 nM
O=C(O)c1cc(-c2cccc(F)c2)ncn1 CHEMBL3407901 IC50 0.3 nM
O=C(O)c1cc(-c2ccc(Cl)c(F)c2)ncn1 CHEMBL3407903 IC50 0.3 nM
O=C(O)c1nccc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3894894 IC50 0.3 nM
O=C(O)c1nccc(-c2cccc(F)c2)n1 CHEMBL3921825 IC50 0.3 nM
O=C(O)c1cc(-c2cccc(Cl)c2)ncn1 CHEMBL3407865 IC50 0.5 nM
O=C(O)c1cc(-c2ccc(OC3CC3)c(Cl)c2)ncn1 CHEMBL3407922 IC50 0.5 nM
O=C(O)c1nccc(-c2ccc(OC3CC3)c(Cl)c2)n1 CHEMBL3960765 IC50 0.5 nM
O=C(O)c1cc(-c2ccc(Cl)c(OC3CC3)c2)ncn1 CHEMBL4740126 IC50 0.5 nM
O=C(O)c1cc(-c2ccc(Cl)c(Cl)c2)ncn1 CHEMBL3407866 IC50 0.6 nM
Cc1ccc(-c2cc(C(=O)O)ncn2)cc1Cl CHEMBL3407913 IC50 0.7 nM
Cc1ccc(-c2ccnc(C(=O)O)n2)cc1Cl CHEMBL3949189 IC50 0.7 nM
O=C(O)c1cc(-c2ccc(F)c(Cl)c2)ncn1 CHEMBL3407902 IC50 0.9 nM
Cc1ccc(-c2cc(C(=O)O)ncn2)cc1F CHEMBL3407914 IC50 0.9 nM
Cc1ccc(-c2ccnc(C(=O)O)n2)cc1F CHEMBL3930333 IC50 0.9 nM
O=C(O)c1nccc(-c2ccc(F)c(Cl)c2)n1 CHEMBL3922876 IC50 0.9 nM
O=C(O)CCn1c(=O)oc2cc(OCc3ccccn3)c(Cl)cc21 CHEMBL4104310 Ki 1.0 nM
COc1ccc(-c2cc(C(=O)O)ncn2)cc1Cl CHEMBL3407920 IC50 1.2 nM
COc1ccc(-c2ccnc(C(=O)O)n2)cc1Cl CHEMBL3983459 IC50 1.2 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1cccnn1 CHEMBL3634602 pIC50 1.259 nM
O=C(O)c1cc(-c2ccc3occc3c2)ncn1 CHEMBL3407924 IC50 1.5 nM
Cc1ccc([C@@H](C)Oc2cc3onc(CCC(=O)O)c3cc2Cl)nc1 CHEMBL4062730 pIC50 1.585 nM
CN(C)c1cccc(S(=O)(=O)Nc2ccc(-c3ccccc3N3CCCC3)nn2)c1 CHEMBL4764931 IC50 1.9 nM
Cc1ccc([C@@H](C)Oc2cc3onc(CCC(=O)O)c3cc2Cl)nn1 CHEMBL4081917 pIC50 1.995 nM
C[C@@H](Oc1cc2sc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4084414 pIC50 1.995 nM
Clc1ccc(-c2cc(-c3nn[nH]n3)ncn2)cc1Cl CHEMBL3407883 IC50 2.0 nM
O=C(O)c1cc(-c2ccc(OC3COC3)c(Cl)c2)ncn1 CHEMBL3407926 IC50 2.0 nM
O=C(O)c1nccc(-c2ccc(OC3COC3)c(Cl)c2)n1 CHEMBL3924368 IC50 2.0 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3cccc4c3N(C)CC4)nn2)cc1 CHEMBL4756311 IC50 2.0 nM
O=C(O)c1cc(-c2ccc(OC(F)(F)F)c(Cl)c2)ncn1 CHEMBL3407919 IC50 2.1 nM
O=C(O)c1nccc(-c2ccc(OC(F)(F)F)c(Cl)c2)n1 CHEMBL3915370 IC50 2.1 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3ccccc3N3CCCCC3)nn2)cc1 CHEMBL4744083 IC50 2.4 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4070050 pIC50 2.512 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccc(F)cn1 CHEMBL4077245 pIC50 2.512 nM
O=C(O)CCn1c(=O)oc2cc(OC3CC3)c(Cl)cc21 CHEMBL4096688 pIC50 3.162 nM
C[C@@H](Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccc(Cl)cn1 CHEMBL4071379 pIC50 3.162 nM
Cc1ccc([C@@H](C)Oc2cc3onc(CCC(=O)O)c3cc2Cl)nc1 CHEMBL4092169 pIC50 3.162 nM
C[C@@H](Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccc(F)cn1 CHEMBL4099913 pIC50 3.162 nM
O=C(O)CCn1c(=O)oc2cc(OCc3ccccn3)c(Cl)cc21 CHEMBL4076924 pIC50 3.162 nM
CC(Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4103315 pIC50 3.162 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ncco1 CHEMBL4075380 pIC50 3.162 nM
Cc1ccc([C@@H](C)Oc2cc3oc(=O)n(CCC(=O)O)c3cc2Cl)nc1 CHEMBL4099039 pIC50 3.162 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccc(Cl)cn1 CHEMBL4086792 pIC50 3.162 nM
C[C@@H](Oc1cc2cnn(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4074106 pIC50 3.162 nM
C[C@@H](Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4100868 pIC50 3.162 nM
O=C(O)c1cc(-c2ccc(Cl)c(Cl)c2)ccn1 CHEMBL3407874 IC50 3.2 nM
CC(Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL3634599 pIC50 3.981 nM
Cc1ccnc([C@@H](C)Oc2cc3oc(=O)n(CCC(=O)O)c3cc2Cl)c1 CHEMBL4075695 pIC50 3.981 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3ccccc3N3CCCC3)nn2)cc1 CHEMBL4781856 IC50 4.1 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3cc(F)ccc3N3CCCCC3)nn2)cc1 CHEMBL4858480 IC50 4.2 nM
O=C(O)c1cc(-c2ccc(C(F)(F)F)c(Cl)c2)ncn1 CHEMBL3407908 IC50 5.0 nM
O=C(O)c1nccc(-c2ccc(C(F)(F)F)c(Cl)c2)n1 CHEMBL3939321 IC50 5.0 nM
CCOc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4071986 pIC50 5.012 nM
C[C@@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ncccn1 CHEMBL4071903 pIC50 5.012 nM
Cc1cccc([C@@H](C)Oc2cc3oc(=O)n(CCC(=O)O)c3cc2Cl)n1 CHEMBL4072423 pIC50 5.012 nM
C[C@@H](Oc1cc2c(cc1Cl)N(CCC(=O)O)C(=O)CO2)c1ccccn1 CHEMBL4064339 pIC50 5.012 nM
C[C@@H](Oc1cc2ccn(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4085877 pIC50 5.012 nM
O=C(O)c1ncnc(-c2ccc(Cl)c(Cl)c2)c1F CHEMBL3407877 IC50 6.0 nM
CC(C)Oc1ccc(-c2cc(C(=O)O)ncn2)cc1Cl CHEMBL3407921 IC50 6.0 nM
CC(C)Oc1ccc(-c2ccnc(C(=O)O)n2)cc1Cl CHEMBL3965088 IC50 6.0 nM
Oc1nc2cc(Cl)c(Cl)cc2o1 CHEMBL1881960 IC50 6.0 nM
O=C(O)CCn1c(=O)oc2cc(Cl)c(Cl)cc21 CHEMBL4092205 IC50 6.0 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3c(F)cccc3N3CCCCC3)nn2)cc1 CHEMBL4849479 IC50 6.1 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3ccc(F)cc3N3CCCCC3)nn2)cc1 CHEMBL4853796 IC50 9.1 nM
Cc1c(C(=O)O)ncnc1-c1ccc(Cl)c(Cl)c1 CHEMBL3407880 IC50 10.0 nM
CCc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4082723 pIC50 10.0 nM
O=C(O)CCn1c(=O)oc2cc(OCC3CC3)c(Cl)cc21 CHEMBL4079327 pIC50 10.0 nM
O=C(O)c1cc(-c2ccc(Cl)cc2)ncn1 CHEMBL3407899 IC50 11.0 nM
O=C(O)c1nccc(-c2ccc(Cl)cc2)n1 CHEMBL3912846 IC50 11.0 nM
Cc1nc(C(=O)O)cc(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL3407876 IC50 12.0 nM
O=c1[nH]c(-c2cc(-c3ccc(Cl)c(Cl)c3)ncn2)no1 CHEMBL3407884 IC50 12.0 nM
O=C(O)c1cc(-c2ccc(OC3CCC3)c(Cl)c2)ncn1 CHEMBL3407925 IC50 12.0 nM
O=C(O)c1nccc(-c2ccc(OC3CCC3)c(Cl)c2)n1 CHEMBL3952066 IC50 12.0 nM
O=C(O)c1cc(-c2ccc(Cl)c(Cl)c2)nc(Cl)n1 CHEMBL3936708 IC50 12.0 nM
Cc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL3634598 pIC50 12.59 nM
COc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4061355 pIC50 12.59 nM
Cc1cc2oc(=O)[nH]c2cc1Cl CHEMBL4064834 pIC50 12.59 nM
O=C(O)CCn1c(=O)oc2ccc(Cl)cc21 CHEMBL4061977 pIC50 12.59 nM
Cc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4076415 pIC50 12.59 nM
CC(C)Cc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4063199 pIC50 12.59 nM
O=S(=O)(CC1CCOCC1)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4854493 IC50 12.8 nM
O=S(=O)(CC1CCCO1)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4872767 IC50 14.0 nM
COc1ccc2c(c1)CN(C1=NC(C(=O)N(C)c3cc(Cl)c(F)cc3C(=O)O)C(Cl)S1)C2 CHEMBL5414238 IC50 14.0 nM
Cn1c(=O)[nH]c(=O)c2cc(-c3ncccc3-c3ccc(Cl)c(F)c3)ccc21 CHEMBL5439164 IC50 14.0 nM
Cc1cccc(-c2cc(C(=O)O)ncn2)c1 CHEMBL3407911 IC50 17.0 nM
Cc1cccc(-c2ccnc(C(=O)O)n2)c1 CHEMBL3977350 IC50 17.0 nM
O=S(=O)(CC1CCCOC1)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4850268 IC50 17.9 nM
O=C(O)c1cc(-c2cc(Cl)cc(Cl)c2)ncn1 CHEMBL3407900 IC50 19.0 nM
O=C(O)c1nccc(-c2cccc(Cl)c2)n1 CHEMBL3949609 IC50 19.0 nM
O=C(O)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1 CHEMBL3407929 IC50 20.0 nM
O=C(O)C1CC1C(=O)c1ccc(Cl)c(Cl)c1 CHEMBL3629571 IC50 20.0 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3cccc(F)c3N3CCCCC3)nn2)cc1 CHEMBL4851794 IC50 20.0 nM
O=C(O)c1cc(-c2cccc(C(F)(F)F)c2)ncn1 CHEMBL3407909 IC50 22.0 nM
O=C(O)c1nccc(-c2cccc(C(F)(F)F)c2)n1 CHEMBL3968864 IC50 22.0 nM
O=C(NS(=O)(=O)c1ccccc1)c1cc(-c2ccc(Cl)c(Cl)c2)ncn1 CHEMBL3407885 IC50 25.0 nM
O=C(O)CCc1noc2ccc(Cl)cc12 CHEMBL4082172 pIC50 25.12 nM
O=C(O)CCn1c(=O)oc2cc(OCC3CCC3)c(Cl)cc21 CHEMBL4089633 pIC50 25.12 nM
O=C(O)CCn1c(=O)oc2cc(OCc3ccccc3)c(Cl)cc21 CHEMBL4059840 pIC50 25.12 nM
CC(C)CS(=O)(=O)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4877327 IC50 27.2 nM
O=S(=O)(CC1CCCC1)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4866526 IC50 28.6 nM
COCCOc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4068504 pIC50 31.62 nM
O=C(O)c1cc(-c2ccc(F)c(C(F)(F)F)c2)ncn1 CHEMBL3407912 IC50 32.0 nM
O=C(O)c1nccc(-c2ccc(F)c(C(F)(F)F)c2)n1 CHEMBL3971724 IC50 32.0 nM
COCc1c(C(=O)O)ncnc1-c1ccc(Cl)c(Cl)c1 CHEMBL3407882 IC50 33.0 nM
COc1ccc(S(=O)(=O)Nc2ncc(-c3cccc([N+](=O)[O-])c3)s2)cc1OC CHEMBL3407930 IC50 33.8 nM
O=S(=O)(CC1CCCCO1)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4869777 IC50 34.1 nM
COc1ccc(S(=O)(=O)Nc2nc(-c3cccc([N+](=O)[O-])c3)cs2)cc1OC CHEMBL134915 IC50 37.0 nM
Cc1ccc(S(=O)(=O)Nc2ncc(-c3cccc([N+](=O)[O-])c3)s2)cc1 CHEMBL4745247 IC50 37.0 nM
CCCS(=O)(=O)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4873105 IC50 37.1 nM
O=C(O)c1cc(-c2ccccc2)ncn1 CHEMBL3407867 IC50 38.0 nM
O=C(O)c1cc(-c2ccc(Cl)cc2F)ncn1 CHEMBL3407907 IC50 38.0 nM
O=C(O)c1nccc(-c2ccc(Cl)cc2F)n1 CHEMBL3948527 IC50 38.0 nM
O=S(=O)(CC(F)(F)F)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4858343 IC50 38.7 nM
O=C(O)CCn1c(=O)oc2cc(C(F)(F)F)c(Cl)cc21 CHEMBL4075968 pIC50 39.81 nM
O=C(O)CCn1ncc2ccc(Br)cc21 CHEMBL4073276 pIC50 39.81 nM
COc1c(C(=O)O)ncnc1-c1ccc(Cl)c(Cl)c1 CHEMBL3407879 IC50 40.0 nM
O=C(O)c1cc(-c2ccc(OCC3CC3)c(Cl)c2)ncn1 CHEMBL3407923 IC50 49.0 nM
O=C(O)c1nccc(-c2ccc(OCC3CC3)c(Cl)c2)n1 CHEMBL3933304 IC50 49.0 nM
O=C(O)CCn1ncc2ccc(Cl)cc21 CHEMBL4060545 pIC50 50.12 nM
O=C(O)c1cc(-c2ccc(OC3CCCC3)c(Cl)c2)ncn1 CHEMBL3407927 IC50 57.0 nM
O=C(O)c1nccc(-c2ccc(OC3CCCC3)c(Cl)c2)n1 CHEMBL3907526 IC50 57.0 nM
COc1cc(-c2cc(C(=O)O)ncn2)ccc1Cl CHEMBL3407915 IC50 60.0 nM
COc1cc(-c2ccnc(C(=O)O)n2)ccc1C CHEMBL3912403 IC50 60.0 nM
COCCCS(=O)(=O)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4846635 IC50 61.6 nM
Cc1cc(Cl)cc2[nH]c(=O)oc12 CHEMBL4064480 pIC50 63.1 nM
O=C(O)c1cc(-c2ccc(F)cc2F)ncn1 CHEMBL3407906 IC50 76.0 nM
O=C(O)c1nccc(-c2ccc(F)cc2F)n1 CHEMBL3977740 IC50 76.0 nM
CC(C)Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4078673 pIC50 79.43 nM
O=C(O)CCN1C(=O)COc2ccc(Cl)cc21 CHEMBL4100173 pIC50 79.43 nM
O=C(O)c1cc(-c2ccc(OCCN3CCOCC3)c(Cl)c2)ncn1 CHEMBL3407917 IC50 83.0 nM
O=C(O)c1nccc(-c2ccc(OCCN3CCOCC3)c(Cl)c2)n1 CHEMBL3931378 IC50 83.0 nM
COCCS(=O)(=O)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4862539 IC50 83.9 nM
O=C(O)c1ccnc(-c2ccc(Cl)c(Cl)c2)c1 CHEMBL3407875 IC50 90.0 nM
CC(C)c1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4060848 pIC50 100.0 nM
N#Cc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl CHEMBL4069680 pIC50 100.0 nM
O=C(O)Cn1ncc2ccc(Cl)cc21 CHEMBL4095901 pIC50 100.0 nM
CCS(=O)(=O)Nc1ccc(-c2ccc(F)cc2N2CCCCC2)nn1 CHEMBL4850797 IC50 115.5 nM
O=C(O)CCn1ccc2ccc(Cl)cc21 CHEMBL4064710 pIC50 125.89 nM
O=C(O)c1ncnc(-c2ccc(Cl)c(Cl)c2)c1O CHEMBL3407878 IC50 140.0 nM
O=C(CC(Cc1ccccc1)C(=O)O)c1ccc(Cl)c(Cl)c1 CHEMBL97993 IC50 180.0 nM
NC(CC(=O)c1ccc(Cl)c(Cl)c1)C(=O)O CHEMBL554000 IC50 200.0 nM
NC(CC(=O)c1ccc(Cl)c(Cl)c1)C(=O)O CHEMBL139909 IC50 200.0 nM
C[C@H](Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 CHEMBL4075981 pIC50 251.19 nM
Nc1c(C(=O)O)ncnc1-c1ccc(Cl)c(Cl)c1 CHEMBL3407881 IC50 260.0 nM
O=S(=O)(Nc1cc(-c2ccc(Cl)c(Cl)c2)ncn1)c1ccccc1 CHEMBL3407886 IC50 270.0 nM
O=C(Nc1ccccc1)c1cc(-c2ccc(Cl)c(Cl)c2)ncn1 CHEMBL3974009 IC50 270.0 nM
O=C(O)c1cc(C2CCCCC2)ncn1 CHEMBL3407869 IC50 340.0 nM
O=C(O)c1cccc(C2CCCCC2)c1 CHEMBL3967583 IC50 340.0 nM
O=C(O)c1cc(-c2ccc(N3CCCC3)c(Cl)c2)ncn1 CHEMBL3407918 IC50 350.0 nM
O=C(O)c1cc(-c2ccc(OC3CCCCC3)c(Cl)c2)ncn1 CHEMBL3407928 IC50 430.0 nM
O=C(O)c1nccc(-c2ccc(OC3CCCCC3)c(Cl)c2)n1 CHEMBL3978057 IC50 430.0 nM
O=C(O)CCn1nnc2ccc(Cl)cc21 CHEMBL4063016 pIC50 501.19 nM
O=C(O)c1nccc(-c2ccc(N3CCCC3)c(Cl)c2)n1 CHEMBL3917417 IC50 550.0 nM
N#Cc1ccc2oc(=O)n(CCC(=O)O)c2c1 CHEMBL4105465 pIC50 630.96 nM
O=C(O)C(O)Cn1ncc2ccc(Cl)cc21 CHEMBL4075997 pIC50 630.96 nM
O=C(O)CCn1c(=O)oc2cc(OCCN3CCCC3)c(Cl)cc21 CHEMBL4081757 pIC50 794.33 nM
NC(CC(=O)c1cccc([N+](=O)[O-])c1)C(=O)O CHEMBL23983 IC50 900.0 nM
NC(CC(=O)c1ccccc1)C(=O)O CHEMBL2040644 IC50 900.0 nM
O=C(O)c1cc(-c2cccnc2)ncn1 CHEMBL3407868 IC50 990.0 nM
O=C(O)c1cccc(-c2cccnc2)c1 CHEMBL3896367 IC50 990.0 nM
COc1ccc2oc(=O)n(CCC(=O)O)c2c1 CHEMBL4081216 pIC50 1000.0 nM
O=C(O)CCn1ncc2cc(Cl)ccc21 CHEMBL4083400 pIC50 1000.0 nM