COc1ccccc1CNc1[nH]cnc2ncnc1-2 CHEMBL1528816 Potency 0.2 nM
COc1ccc(S(=O)(=O)N2CCN(C(=O)C3CC3)CC2)cc1Br CHEMBL1512450 Potency 0.3 nM
CCc1ccccc1NC(=O)CNC(=O)c1cc(C2CC2)nn1-c1ccccc1 CHEMBL1433553 Potency 0.3 nM
Cc1ccc(N2C(=O)NC(=O)/C(=C/NCC3CCCO3)C2=O)c(C)c1 CHEMBL1540844 Potency 0.3 nM
CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)n1c(=O)[nH]c2ccccc2c1=O)C(=O)N1CCC(C(=O)O)CC1 CHEMBL1397345 Potency 0.3 nM
CCn1cc(CNC(=O)C2C3CCC(C3)C2C(=O)O)cn1 CHEMBL1399069 Potency 0.6 nM
CSCCC(NC(=O)c1ccco1)C(=O)NCCc1ccc(F)cc1 CHEMBL1561787 Potency 0.6 nM
O=C(Cc1c(Cl)cccc1Cl)NC1=NCCS1 CHEMBL1391113 Potency 0.8 nM
Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 CHEMBL1465947 Potency 0.8 nM
COc1ccc(C(=O)NC2CCN(C(S)=Nc3cccc(C)c3C)CC2)cc1 CHEMBL1384761 Potency 0.9 nM
c1cncc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 CHEMBL1383055 Potency 1.1 nM
Cn1c2ccccc2c(=O)c2c(=O)n(-c3ccc(F)cc3)c(-c3cccs3)nc21 CHEMBL1366206 Potency 1.1 nM
Cn1cc(CNC(=O)C2c3ccccc3Oc3ccccc32)cn1 CHEMBL1459193 Potency 1.3 nM
CCC(=O)N1CCc2cc(S(=O)(=O)NCCC(=O)Nc3cc(C)cc(C)c3)ccc21 CHEMBL1464826 Potency 2.0 nM
CCOc1ccc2nc(N3CCC(C(=O)N4CCN(C5CCCCC5)CC4)CC3)sc2c1 CHEMBL1348716 Potency 2.0 nM
CC1(C)CC(=O)C2=C(C1)N(Cc1cccnc1)C(=O)C2(NC(=O)c1ccc(F)cc1)C(F)(F)F CHEMBL1573631 Potency 2.5 nM
O=C(CCCCCN1C(=O)c2cccc3cccc(c23)C1=O)NCc1ccco1 CHEMBL1386435 Potency 2.5 nM
COC(=O)COc1cccc2c(=O)n(CC(=O)NCCc3ccc(OC)c(OC)c3)ccc12 CHEMBL1438556 Potency 3.2 nM
Cc1ccc(CNC(=O)c2ccc(C)c(S(=O)(=O)N3CCCCC3)c2)cc1 CHEMBL1474221 Potency 3.2 nM
COc1ccc(NC(=O)COc2ccc(C(=O)NC3CCCc4ccccc43)cc2OC)cc1 CHEMBL1598177 Potency 3.5 nM
COc1ccc(C(=O)OC(C)C(=O)NC2CCCCC2C)cc1S(=O)(=O)N1CCOCC1 CHEMBL1398109 Potency 5.0 nM
Cc1cc(NC(=O)COC(=O)C2COc3ccccc3O2)no1 CHEMBL1469237 Potency 5.0 nM
N#Cc1c(-c2ccc(Cl)cc2)c(C#N)c(=O)n(N)c1N CHEMBL1492129 Potency 5.0 nM
CCOC(=O)C1(CC2CC2)CCN(C(=O)c2cc(C3CC3)nc3ccccc23)CC1 CHEMBL1502347 Potency 5.0 nM
NS(=O)(=O)c1ccc(CCNC(=O)COC(=O)C2CCN(c3ccc(C(F)(F)F)cn3)CC2)cc1 CHEMBL1434495 Potency 5.6 nM
CC(NC(=O)CSc1ccccc1C(=O)O)C1CC2CCC1C2 CHEMBL1405256 Potency 6.3 nM
Cc1c(NC(=O)/C(C#N)=C/c2c(Oc3ccccc3)nc3ccccn3c2=O)c(=O)n(-c2ccccc2)n1C CHEMBL1364547 Potency 6.3 nM
Cc1ccc(C)c(N(CC(=O)N2CCCC2)S(C)(=O)=O)c1 CHEMBL1513210 Potency 7.1 nM
CC(C)C(=O)Nc1ccc(C(=O)NNC(=O)c2cccs2)cc1 CHEMBL1353247 Potency 7.1 nM
O=C(C1CCCN1S(=O)(=O)c1ccc(Br)cc1)N1CCOCC1 CHEMBL1511600 Potency 7.1 nM
Cc1ccc(S(=O)(=O)NCCNC(=O)CN2CCCC2)cc1 CHEMBL1497180 Potency 7.9 nM
COc1cc(CN(C(S)=NCC(=O)NC2CC2)C2CCCC2)cc(OC)c1OC CHEMBL1548993 Potency 7.9 nM
CCOC(=O)NC(=O)CSc1ccc2ccccc2n1 CHEMBL1349662 Potency 8.9 nM
Cc1ccc(C(c2nnnn2CS(=O)(=O)c2ccc(C)cc2)N2CCC(C(N)=O)CC2)cc1 CHEMBL1429803 Potency 8.9 nM
C/C(Cc1ccccc1)=N\NC(=O)c1ccc(F)cc1 CHEMBL3192714 Potency 8.9 nM
CCc1c(C(=O)NCc2cnn(C)c2)csc1C CHEMBL1303448 Potency 8.9 nM
COc1ccc(S(=O)(=O)NC(CC(C)C)C(=O)NC(C)c2cccs2)cc1 CHEMBL1360930 Potency 8.9 nM
CCCCCC(=O)Nc1ccc(Cl)cn1 CHEMBL1522086 Potency 8.9 nM
CC(C)CN=C(S)Nc1ccccc1F CHEMBL1458027 Potency 10.0 nM
O=C(C1CCCN(S(=O)(=O)c2cccnc2)C1)N1CCn2c1nc1ccccc12 CHEMBL1383792 Potency 10.0 nM
COc1ccccc1C1=CC(=O)CC(C)(C)C1=O CHEMBL1314718 Potency 11.2 nM
CC(C)Cc1nnc(NC(=O)CCNC(=O)c2ccccc2Cl)s1 CHEMBL1331365 Potency 11.2 nM
COc1ccc(OC)c(/C=C/C(=O)OCC(=O)NCc2cccs2)c1 CHEMBL1551746 Potency 11.2 nM
COc1ccccc1C(C)NC(=O)CCNC(=O)c1ccc(Cl)cc1 CHEMBL1367140 Potency 12.6 nM
C=CCN1C(=O)NC(=O)/C(=C\NCCCn2ccnc2)C1=O CHEMBL1423117 Potency 12.6 nM
Cc1cc(C)n(-c2nc3ccccc3c(=O)n2OCc2ccc(F)cc2)n1 CHEMBL1301812 Potency 12.6 nM
COc1ccc(NC(=O)N2CCCc3cccc(C)c32)cc1 CHEMBL1378797 Potency 14.1 nM
CN1C(=O)OC(C)(CCc2ccccc2)C1(C)O CHEMBL1300025 Potency 15.8 nM
Cc1ccnc(NC(=O)CSc2cc(=O)n(C)c3ccccc23)c1 CHEMBL1420204 Potency 15.8 nM
CN(c1ccccc1)S(=O)(=O)c1cccc(NC(=O)CSc2ncc(C(F)(F)F)cc2Cl)c1 CHEMBL1342722 Potency 15.8 nM
Cn1c(CNC(=O)c2ccccc2F)nnc1SCc1ccc(F)cc1 CHEMBL1467330 Potency 17.8 nM
COCC(C)NC(=O)C1c2ccccc2Oc2ccccc21 CHEMBL1576043 Potency 20.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C(=O)N(CC(C)C)C3=O)c1 CHEMBL1386639 Potency 20.0 nM
COc1ccccc1C(=O)O/N=C(\N)c1ccccc1Cl CHEMBL1343476 Potency 22.4 nM
COc1cccc(C(=O)NCCS(=O)(=O)N2CC(C)CC(C)C2)c1 CHEMBL1320399 Potency 22.4 nM
CCOC(=O)c1ccc(N(C(=O)c2cnccn2)C(C(=O)NC2CCCCC2)c2cn(C)nc2C)cc1 CHEMBL1429308 Potency 25.1 nM
CN(CC(=O)NCc1ccc2c(c1)OCO2)CC(=O)Nc1ccc(F)c(F)c1F CHEMBL1485390 Potency 25.1 nM
CCOC(=O)c1[nH]c(C)c(C(=O)N(C)C)c1C CHEMBL1549439 Potency 25.1 nM
CCCN1CCN(C(=O)c2cc(COc3ccc4ncccc4c3)on2)CC1 CHEMBL1432803 Potency 25.1 nM
O=C(CC(=O)Nc1ccccc1C(=O)O)NNC(=O)Cc1ccccc1 CHEMBL1499434 Potency 25.1 nM
CCn1c(COc2cccc(C)c2)nnc1SCC(=O)N1CCCC1 CHEMBL1562072 Potency 25.1 nM
COc1ccc([C@H]2[C@H](C(C)=O)N3N=Cc4ccccc4C3C23C(=O)OC(C)(C)OC3=O)cc1 CHEMBL1361231 Potency 25.1 nM
COc1cccc(NC(=O)CN(c2cccc(C(F)(F)F)c2)S(C)(=O)=O)c1 CHEMBL1418726 Potency 28.2 nM
CC1CCc2sc(C(=O)OC(C)C(=O)Nc3ncc(Cl)cc3Cl)cc2C1 CHEMBL1595160 Potency 28.2 nM
Cc1noc(C)c1S(=O)(=O)N(C)C[C@H]1Oc2ccc(NS(=O)(=O)c3ccccc3)cc2C(=O)N([C@H](C)CO)C[C@@H]1C CHEMBL1512560 Potency 28.2 nM
O=C(O)CSCC(=O)NCc1ccccc1Cl CHEMBL1361631 Potency 28.2 nM
Oc1nc(CSc2ncccn2)nc2c1cnn2-c1ccccc1 CHEMBL1415103 Potency 28.2 nM
O=[N+]([O-])c1cccc(S(=O)(=O)NCc2ccccn2)c1 CHEMBL1564456 Potency 28.2 nM
Cc1ccc(C)c(NC(=O)Cn2nc(-c3ccccc3)nc2-c2ccccc2)c1 CHEMBL1471149 Potency 28.2 nM
O=C(COc1ccccc1Br)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1553222 Potency 28.2 nM
CSc1ncccc1C(=O)OCC(=O)c1ccc(C)s1 CHEMBL1315210 Potency 28.2 nM
C=C(C)Cn1c(CCCNC(=O)C(C)(C)C)nc2ccccc21 CHEMBL1490736 Potency 28.2 nM
O=C(/C(Cl)=C/Nc1ccc(Br)cn1)C(F)(F)F CHEMBL1372788 Potency 28.2 nM
Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 CHEMBL1387110 Potency 28.2 nM
COc1ccc(Cl)cc1C(=O)NNC(=O)CCNS(=O)(=O)c1ccccc1 CHEMBL1438405 Potency 31.6 nM
COCCN(C(=O)c1cc(Cl)nc2ccccc12)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O CHEMBL1370094 Potency 31.6 nM
CCOC(=O)c1ccc(Nc2cc(C)nc3ncnn23)cc1 CHEMBL483325 Potency 31.6 nM
Cc1ccccc1N(CC(=O)NCCSc1ccccn1)S(=O)(=O)c1ccccc1 CHEMBL1338816 Potency 31.6 nM
O=C(O)CCCCCNc1nc(S)nc2ccccc12 CHEMBL1585417 Potency 31.6 nM
O=C(c1ccco1)N1CCN(Cc2nc(Cc3ccccc3)no2)CC1 CHEMBL1613673 Potency 31.6 nM
CCOc1ccc(C(C)=O)cc1COC(=O)C1=COCCO1 CHEMBL1469423 Potency 31.6 nM
CC(C)CCN1CCN(CCCn2cccn2)CC1CCO CHEMBL1351405 Potency 31.6 nM
O=C1C2CCCN2C(c2cccs2)N1c1ccccn1 CHEMBL1335022 Potency 31.6 nM
COc1cccc(-n2c(S)nnc2CNC(=O)OC(C)(C)C)c1 CHEMBL1532258 Potency 31.6 nM
CNS(=O)(=O)c1ccc2ccccc2c1 CHEMBL1403828 Potency 31.6 nM
O=C(CCCC(=O)N(CC(=O)NC1CCCC1)Cc1ccccc1)Nc1ccccn1 CHEMBL1324264 Potency 31.6 nM
O=C(CSCc1c(F)cccc1Cl)NCc1cccnc1 CHEMBL1523302 Potency 31.6 nM
Cc1ccc(N(CCC#N)C(=O)COC(=O)c2ccccc2SCC(=O)N2CCCC2)cc1 CHEMBL1593630 Potency 31.6 nM
O=C(C[n+]1cc(-c2ccc(Cl)c(Cl)c2)n2c1CCC2)N1c2ccccc2Sc2ccccc21 CHEMBL1500500 Potency 31.6 nM
O=c1c2c(ncn2C2CCCC2)n(Cc2ccccc2)c(=O)n1CCOc1ccccc1 CHEMBL1375489 Potency 31.6 nM
O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O CHEMBL275938 Potency 35.5 nM
N#Cc1cc2c(nc1S(=O)(=O)Cc1ccccc1)CCCC2 CHEMBL1497543 Potency 35.5 nM
COc1ccc(OC)c(S(=O)(=O)n2nnc3cc(Cl)ccc32)c1 CHEMBL1400008 Potency 35.5 nM
O=C(NCCC1=CCCCC1)c1ccc(-n2cncn2)c([N+](=O)[O-])c1 CHEMBL1416903 Potency 35.5 nM
CN(Cc1ccccc1)C(=O)COC(=O)CCC(=O)c1ccc(F)cc1 CHEMBL1411015 Potency 35.5 nM
CCc1ccc(NC(=O)N(C2CCC(C)CC2)C2CCN(C(C)=O)CC2)cc1 CHEMBL1577150 Potency 35.5 nM
O=C1NCCCC1C(=O)N1CCN(C(=O)C2CCCNC2=O)CC1 CHEMBL1346203 Potency 35.5 nM
FC(F)(F)c1cc(-c2ccccn2)nc2cc(-c3ccccc3)nn12 CHEMBL1580193 Potency 35.5 nM
CCOC(=O)CSc1nnnn1-c1cc(OC)c(Cl)cc1OC CHEMBL1336936 Potency 35.5 nM
CCc1nc2ccccc2n1CC(=O)Nc1cc(C)on1 CHEMBL1347010 Potency 35.5 nM
Cc1ccc(C(=O)Cn2cc(-c3ccc(C)cc3)[n+]3c2CCCCC3)cc1 CHEMBL1347156 Potency 35.5 nM
CCc1cccc2c(SCC(=O)NCC3CCCO3)nc(-c3ccc(F)cc3)nc12 CHEMBL1477203 Potency 39.8 nM
COc1cc(OC)c2ccc(=O)oc2c1 CHEMBL481049 Potency 39.8 nM
CC(C)c1csc(CN2CCN(Cc3ccc(F)cc3)C(CCO)C2)n1 CHEMBL1507703 Potency 39.8 nM
O=C(O)CC(Cc1ccc(Cl)cc1)C(=O)Nc1cc(Cl)ccc1Cl CHEMBL1311446 Potency 39.8 nM
COc1cccc(OCC(O)CN2CCOCC2)c1 CHEMBL1392101 Potency 39.8 nM
Cc1ccc(C(=O)NNS(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL1377536 Potency 39.8 nM
Fc1ccc2cnc(CCO[C@H]3CCCCO3)cc2c1 CHEMBL1493764 Potency 39.8 nM
c1cc2c(cc1-c1n[nH]cc1CN1C[C@H]3C[C@H]4C[C@@H](C3)C[C@H]1C4)OCO2 CHEMBL1581739 Potency 39.8 nM
COc1ccc(C2=NOC(Cn3nc(-c4ccccc4)cc3C(=O)NCc3cccc(Br)c3)C2)cc1 CHEMBL1376867 Potency 39.8 nM
O=C(c1ccncc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 CHEMBL1338569 Potency 39.8 nM
Cc1ccc(Nc2cc(C)nc3ccc(C)cc23)cc1 CHEMBL1300694 Potency 44.7 nM
O=C(O)CCCCCCCCc1cn(CN2C(=O)c3ccccc3C2=O)nn1 CHEMBL1473251 Potency 44.7 nM
CCC(C)[C@H](NC(=O)N1CC(=O)Nc2ccccc21)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O CHEMBL1475836 Potency 50.1 nM
C/C(=N/N=C1\SCC(=O)N1c1ccccc1)c1ccc(C)cc1 CHEMBL3214086 Potency 50.1 nM
O=C(NN=Cc1ccc(F)cc1)c1cccc(S(=O)(=O)N2CCCC2)c1 CHEMBL1559613 Potency 56.2 nM
OCC1=C[C@@H](O)[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12 CHEMBL514882 Potency 63.1 nM
CS(=O)(=O)N1CCN(c2ccccc2NC(=O)c2ccco2)CC1 CHEMBL1428545 Potency 63.1 nM
NC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12 CHEMBL1340620 Potency 70.8 nM
O=C(NCCc1ccccc1)c1cc2ccccc2oc1=O CHEMBL469977 Potency 70.8 nM
COC1=CC2[C@@H]3Cc4ccc(OC)c(O)c4[C@]2(CCN3C)CC1=O CHEMBL1589951 Potency 70.8 nM
Nc1nnc(-c2ccccc2[N+](=O)[O-])o1 CHEMBL1471805 Potency 70.8 nM
Cn1c(=O)c2c(nc(CN3CCN(c4ccc(F)cc4)CC3)n2Cc2ccccc2F)n(C)c1=O CHEMBL1347778 Potency 70.8 nM
COc1ccc(-c2cc3ncc(-c4ccccc4)c(N)n3n2)cc1 CHEMBL1585055 Potency 70.8 nM
COc1ccccc1N1CCN(C(=O)c2ccc3[nH]cnc3c2)CC1 CHEMBL1309846 Potency 79.4 nM
CNS(=O)(=O)c1ccc(C(=O)NCC(=O)NC(C)c2cccs2)cc1 CHEMBL1439211 Potency 79.4 nM
COc1cccc(CNC(=O)CCCC(=O)NC(C)CCc2ccccc2)c1 CHEMBL1422855 Potency 79.4 nM
Cc1ccc(CC(=O)NCC[S+]([O-])c2ccc(C)cc2)cc1 CHEMBL1503422 Potency 79.4 nM
C/C(=N\NC(=O)CSc1[nH]c(C)nc1[N+](=O)[O-])c1ccc(F)cc1 CHEMBL3211496 Potency 79.4 nM
CC(=O)n1c2ccccc2c2nc3ccccc3nc21 CHEMBL1558712 Potency 79.4 nM
CCOC(=O)C1C2c3ccccc3OC1(C)N=C1SCC(=O)N12 CHEMBL1529550 Potency 79.4 nM
Cc1ccc(N2CS(=O)(=O)/C(=C/N(C)C)C2=O)cc1 CHEMBL1492702 Potency 79.4 nM
COP(=O)(NC(=O)C(Cl)(Cl)Cl)OC CHEMBL1538884 Potency 79.4 nM
COc1ccc(NC(=O)CNC(=O)c2ccc([N+](=O)[O-])cc2)cc1 CHEMBL1543209 Potency 79.4 nM
Cc1ccccc1N=C(S)Nc1ccc(Br)cc1 CHEMBL1489566 Potency 79.4 nM
C(=N/Nc1ccccc1)\c1nc2ccccc2s1 CHEMBL3190318 Potency 79.4 nM
O=C1CCCN1CC1CCN(Cc2nc(CC3CC3)no2)CC1 CHEMBL1321077 Potency 79.4 nM
O=C(C1CCN(S(=O)(=O)N2CCOCC2)CC1)N1CCC2(CC1)OCCO2 CHEMBL1455172 Potency 79.4 nM
Cc1ccc(C2=CC(c3cccs3)n3nnnc3N2)cc1 CHEMBL1599440 Potency 79.4 nM
Cc1ccc(C2=NN(C(=O)CCC(=O)O)C(c3cccc([N+](=O)[O-])c3)C2)cc1 CHEMBL1601173 Potency 79.4 nM
COc1ccc(/C=C2/C(=O)N(c3c(F)c(F)c(F)c(F)c3F)N=C2C)cc1 CHEMBL1522005 Potency 79.4 nM
CCOC(=O)N1CCC(N2CCCC(C(=O)c3cccc(OC(C)C)c3)C2)CC1 CHEMBL1369673 Potency 89.1 nM
O=C(Nc1cccnc1)c1ccccc1NS(=O)(=O)c1ccc(F)cc1 CHEMBL1299698 Potency 89.1 nM
C=CC[C@H](CC(=O)N(CCO)Cc1ccccc1)C(=O)NC[C@@H](OC(=O)[C@@H](CC=C)Cc1ccc(F)cc1)c1ccccc1 CHEMBL1553481 Potency 89.1 nM
COc1ccccc1Oc1ccccc1[N+](=O)[O-] CHEMBL1537076 Potency 89.1 nM
C=C[C@@]1(C)CCC(/C(C)=C/C=C/C(C)(C)O)C[C@@H]1C(=C)C CHEMBL1399246 Potency 89.1 nM
O=C1C2CCCN2C(c2ccc(Cl)cc2)N1c1ccccn1 CHEMBL1340355 Potency 89.1 nM
Cc1cc(C)n(CC2CC(=O)N(c3ccc(F)c(Cl)c3)C2=O)n1 CHEMBL1339285 Potency 89.1 nM
CCOc1ccccc1N1CC(C(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)CC1=O CHEMBL1551382 Potency 89.1 nM
Cc1cc(C)c(NC(=O)CSc2nc(COc3ccccc3)nc3ccccc23)c(C)c1 CHEMBL1575194 Potency 89.1 nM
CC(C)(O)C#Cc1ccc(CN2CCN(Cc3ccccc3)C(CCO)C2)s1 CHEMBL1487262 Potency 89.1 nM
COc1ccc(NS(=O)(=O)c2cccc(C(=O)N(C)Cc3cccs3)c2)cc1 CHEMBL1447861 Potency 89.1 nM
CN(C)c1nn(C(=O)Nc2ccc(Cl)cc2Cl)cc1-c1ccccc1 CHEMBL1330886 Potency 89.1 nM
CC(C)n1ncc2c(C(=O)NCC(=O)Nc3ccccc3Br)cc(C3CC3)nc21 CHEMBL1330888 Potency 89.1 nM
Cc1ccc(-c2nnc(CSc3nc(C)nc4sc(C)c(C)c34)o2)cc1 CHEMBL1537883 Potency 89.1 nM
O=c1ccn(CCOc2ccc(Cl)cc2)c(=O)[nH]1 CHEMBL1487665 Potency 89.1 nM
N#Cc1ccc(CSc2nc(N)cc(N)n2)cc1 CHEMBL1333827 Potency 89.1 nM
COc1c(Cl)cc(Cl)cc1/C=N/n1cnnc1 CHEMBL3190916 Potency 89.1 nM
COc1ccccc1NC(=O)c1cc(Cl)nnc1Cl CHEMBL1428836 Potency 89.1 nM
CCOC(=O)C1C(=O)CC(O)(c2ccccc2)CC1c1ccccc1 CHEMBL1418181 Potency 89.1 nM
COCCOc1ccc(C(F)(F)F)cc1NC(=O)CN1C(=O)NC(C)(c2ccc3c(c2)OCO3)C1=O CHEMBL1326671 Potency 89.1 nM
CCCCCOc1ccc(/C=C/C(=O)NCCc2nc3ccccc3[nH]2)cc1OC CHEMBL1339141 Potency 89.1 nM
CCOc1cccc(C(=O)NC2=NCCS2)c1 CHEMBL1310006 Potency 89.1 nM
COc1ccc(C(=O)N2CCC(C(=O)Nc3ccccc3C)CC2)cc1OC CHEMBL1530059 Potency 89.1 nM
CC(OC(=O)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1)C(=O)NC1CCCC1 CHEMBL1575071 Potency 89.1 nM
COc1ccc(-n2nc(C(C)=O)c(=O)[nH]c2=O)cc1 CHEMBL1507826 Potency 89.1 nM
COCCOC(=O)C1=C(C)NC(=O)NC1c1cccs1 CHEMBL1451674 Potency 89.1 nM
C[C@]12CC[C@H](N)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2O CHEMBL1476716 Potency 89.1 nM
CCC(C)[C@H](NC(=O)N1CC(=O)Nc2ccccc21)C(=O)N1CCC[C@@H]1C(=O)O CHEMBL1318343 Potency 89.1 nM
COc1ccccc1-n1nnnc1SCC(=O)N(C)C1CCS(=O)(=O)C1 CHEMBL1367333 Potency 89.1 nM
CCOC(=O)Cn1nc(Cc2ccccc2)c2ccccc2c1=O CHEMBL1350898 Potency 89.1 nM
O=C(Cc1ccc([N+](=O)[O-])cc1)N1N=C2CCCCC2C1(O)C(F)(F)F CHEMBL1391223 Potency 89.1 nM
CCC[C@@H]1C[C@@H](C(=O)N[C@@H](C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[C@H](C)Cl)N(C)C1 CHEMBL1452303 Potency 89.1 nM
CNc1nc(SCC(=O)OC)nc(N2CCOCC2)n1 CHEMBL1351718 Potency 89.1 nM
Cc1cc(C)c(C#N)c(SCC(=O)C(C)(C)C)n1 CHEMBL1564032 Potency 89.1 nM
O=C(NCc1ccccc1)c1cc(S(=O)(=O)N2CCC3(CC2)OCCO3)ccc1F CHEMBL1602767 Potency 89.1 nM
O=C(O)CSC1CC(=O)N(c2cccc(Cl)c2)C1=O CHEMBL1333943 Potency 89.1 nM
COc1ccc(-c2noc(C3CCCN(C(=O)c4ccccc4OC)C3)n2)cc1OC CHEMBL1311969 Potency 89.1 nM
Cc1ccc(C(=O)N/N=c2\sc3ccccc3n2C)cc1 CHEMBL3208281 Potency 89.1 nM
C[C@H]1CC[C@H]2NCCN[C@H]2C1 CHEMBL1334064 Potency 89.1 nM
Cc1ccc(C(=O)NNC(=O)C2CSC3(C)CCC(=O)N23)cc1 CHEMBL1564182 Potency 89.1 nM
CN(C)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 CHEMBL1351967 Potency 89.1 nM
Cn1nnnc1Sc1ncnc2scc(-c3ccc(F)cc3)c12 CHEMBL1378851 Potency 89.1 nM
CCOc1ccc(NC(=O)COC(=O)C2CC2C)cc1 CHEMBL1394267 Potency 89.1 nM
O=C(O)c1ccccc1N1C(=O)C2C3CCC(C3)C2C1=O CHEMBL1432020 Potency 89.1 nM
COc1ccc(/C=C/C(=O)NC(=S)NNC(=O)c2cccs2)cc1 CHEMBL1432518 Potency 89.1 nM
CCCNC(=O)NS(=O)(=O)c1cnccc1Sc1ccc(Cl)c(Cl)c1 CHEMBL1472183 Potency 89.1 nM
Cc1ccc(Oc2ncccc2C(=O)NC2CCSC2=O)cc1 CHEMBL1498786 Potency 89.1 nM
Cn1ncc2c(N3CCN(c4ccc(Cl)c(Cl)c4)CC3)ncnc21 CHEMBL1491637 Potency 89.1 nM
Cc1ccccc1Nc1nnc(C)c(=O)n1N CHEMBL1606023 Potency 89.1 nM
CC1(C)CC(=O)C2(CC3=C(CC(C)(C)CC3=O)O2)C(=O)C1 CHEMBL1598489 Potency 89.1 nM
CCCC(=O)Nc1ccccc1-c1nnn(CC(=O)Nc2ccc(OCC)cc2)n1 CHEMBL1345573 Potency 89.1 nM
Cn1c2ccccc2c(=O)c2cc(NCCCN3CCOCC3)ccc21 CHEMBL1357528 Potency 89.1 nM
Cc1ccc(C(=O)N2CCCN(C(=O)c3ccc(C)o3)CC2)o1 CHEMBL1581100 Potency 89.1 nM
O=C(CCC(=O)c1cccs1)NCc1ccccc1 CHEMBL1387566 Potency 89.1 nM
Nc1ccccc1C(=O)N1CCc2ccccc21 CHEMBL1583231 Potency 89.1 nM
Cc1cc(N2C(=O)C3CCCN3C2c2ccccc2)no1 CHEMBL1595534 Potency 89.1 nM
CCOC(=O)c1cc(-c2ccc(OC)cc2)[nH]n1 CHEMBL1489428 Potency 89.1 nM
CC(=O)Nc1cccc(NS(=O)(=O)c2ccccc2[N+](=O)[O-])c1 CHEMBL1577153 Potency 89.1 nM
COCCNC(=O)CN(C(=O)CCC(=O)Nc1ccccn1)c1ccc(OC)cc1 CHEMBL1567945 Potency 89.1 nM
NC(=S)N/N=C1\CCOc2ccc(F)cc21 CHEMBL1974091 Potency 89.1 nM
CC(=O)Nc1ccc(CN2CCCC(CO)(Cc3ccccc3C)C2)cc1 CHEMBL1501293 Potency 89.1 nM
O=C(O)c1ccc(N=Nc2c(O)[nH]c3ccccc23)cc1 CHEMBL1401676 Potency 89.1 nM
Cc1ccc(NC(S)=NN(C)c2cc(C)nc(C)n2)cc1 CHEMBL1540269 Potency 89.1 nM
Cc1c(C)c(C)c(/C=[N+](/C)[O-])c(C)c1C CHEMBL1501366 Potency 89.1 nM
Cc1nc(SCc2nc3cc([N+](=O)[O-])ccc3[nH]2)c2oc3ccccc3c2n1 CHEMBL1335841 Potency 89.1 nM
COc1cc(OC)c(NC(=O)CCNC(=O)Cn2ccc3ccccc3c2=O)cc1Cl CHEMBL1403225 Potency 89.1 nM
Cc1scc2c1N(C(=O)CN1CCN(C)CC1)c1ccccc1NC2=O CHEMBL253978 Potency 89.1 nM
Cn1ncc2c1ncn1nc(COc3ccc4ccccc4c3)nc21 CHEMBL1381526 Potency 89.1 nM
O=C1c2ccccc2C(=O)N1CCSc1nc[nH]n1 CHEMBL1605283 Potency 89.1 nM
CCS(=O)(=O)N1CCC(NC(=O)C(Cc2cccc(OC)c2OC)NC(C)=O)CC1 CHEMBL1441072 Potency 89.1 nM
Cc1cc(CNC(=O)COc2ccc(F)cc2Cl)cc(C)c1O CHEMBL1558835 Potency 89.1 nM
COCCCN(C(S)=Nc1cccc(Cl)c1)C(C)c1ccncc1 CHEMBL1453020 Potency 89.1 nM
Cc1ccc(CNC(=O)c2cc(C(=O)NCc3ccc(C)cc3)n(C)n2)cc1 CHEMBL1315896 Potency 89.1 nM
CCCN1C(=O)/C(=C/c2c(NCCCOCC)nc3c(C)cccn3c2=O)SC1=S CHEMBL1612455 Potency 89.1 nM
CCOC(=O)c1ccc(NC(=O)CSc2nnc(C3CC3)n2C)cc1 CHEMBL1427405 Potency 89.1 nM
O=C1CN(C(=O)COC(=O)c2cnc(Cl)c(Cl)c2)c2ccccc2N1 CHEMBL1466557 Potency 89.1 nM
Cc1ccc(C(=O)CSc2nnc(C(C)C)n2C)cc1C CHEMBL1490097 Potency 89.1 nM
Cn1nc(-c2ccc(C(=O)NCC3CCCO3)cc2)c2ccccc2c1=O CHEMBL1414278 Potency 89.1 nM
COc1ccc(CCNC(=O)CN2C(=O)NC(c3ccccc3)(c3ccccc3)C2=O)cc1 CHEMBL1357373 Potency 89.1 nM
CCCCc1c(O)n(-c2ccccc2C)c(SCC(=O)NC(C)(C)C)nc1=O CHEMBL1579774 Potency 89.1 nM
CN1CCN(c2ccc(Cl)cc2NC(=O)CN2C(=O)NC(C)(c3ccccc3)C2=O)CC1 CHEMBL1323803 Potency 89.1 nM
O=C(CN1C(=O)C2C3c4ccccc4C(c4ccccc43)C2C1=O)Nc1ccccc1C(=O)O CHEMBL1306123 Potency 89.1 nM
c1coc(CNc2c3c(nc4ncnn24)CCC3)c1 CHEMBL1444217 Potency 89.1 nM
CCc1nnc(NC(=O)C(=O)NCCOC(=O)c2ccccc2Cl)s1 CHEMBL1427893 Potency 89.1 nM
COc1ccc(C(=O)NCC(=O)N2CCc3ccccc3C2)cc1 CHEMBL1557408 Potency 89.1 nM
O=C(CCN1C(=O)c2ccccc2C1=O)Nc1ccncc1 CHEMBL1518130 Potency 89.1 nM
COc1ccc(N2C(=O)CC(Sc3n[nH]c(-c4ccccc4)n3)C2=O)cc1 CHEMBL1360902 Potency 89.1 nM
Cc1cccnc1NC(=O)c1ccccc1-c1ccccc1C(=O)Nc1ncccc1C CHEMBL1423686 Potency 89.1 nM
COc1ccc(S(=O)(=O)N(C)C[C@H]2Oc3ccc(NC(=O)NC4CCCCC4)cc3C(=O)N([C@H](C)CO)C[C@@H]2C)cc1 CHEMBL1552790 Potency 89.1 nM
CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(NC(=O)Cc3ccccc3)C2SC1 CHEMBL1506267 Potency 89.1 nM
COc1ccc(C(=O)N[C@H]2COC(C)(C)O[C@H]2c2ccccc2)cc1 CHEMBL1460520 Potency 89.1 nM
Cc1nn(C)c(Cl)c1CN1CCCC(CO)(Cc2cccc(Cl)c2)C1 CHEMBL1382223 Potency 89.1 nM
O=C1CCN(Cc2ccc(O)cc2)CCN1[C@H](CO)c1ccccc1 CHEMBL1490686 Potency 89.1 nM
COc1ccccc1N1CCN(C(=O)/C=C/c2cccc([N+](=O)[O-])c2)CC1 CHEMBL1412206 Potency 89.1 nM
CN1CCCN(C(=O)CNC(=O)Cc2ccccc2)CC1 CHEMBL1382255 Potency 89.1 nM
Cc1nnc2ccc(-c3cccc(NS(=O)(=O)c4ccccc4[N+](=O)[O-])c3)nn12 CHEMBL1518504 Potency 89.1 nM
O=C1CCCN1c1ccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)cc1 CHEMBL1532094 Potency 89.1 nM
O=C(c1cnc2n(c1=O)CCS2)N(c1ccccc1)C1CCCCC1 CHEMBL1423897 Potency 89.1 nM
CCCCCC(=O)N1CCCC1 CHEMBL1370892 Potency 89.1 nM
COc1cccc(CNC(=O)C2CCCN(c3nc4ccccc4o3)C2)c1 CHEMBL1482471 Potency 89.1 nM
CCN1C(=O)[C@H]2[C@H]3CN=C(SCc4ccc(C)cc4)N3[C@@](CC)(C(=O)OC)[C@H]2C1=O CHEMBL1472461 Potency 89.1 nM
CN(C)c1nc(Nn2cnnc2)nc(N(C)C)n1 CHEMBL1308927 Potency 89.1 nM
COc1cc(C2NC(=O)NC(C)=C2C(C)=O)ccc1O CHEMBL1342564 Potency 89.1 nM
CCOC(=O)C1(Cc2ccccc2C)CCCN(C(=O)c2ccnn2C)C1 CHEMBL1375228 Potency 89.1 nM
CCOC(=O)N1CCN(c2nc3c(c(=O)[nH]c(=O)n3C)n2Cc2ccccc2Cl)CC1 CHEMBL1541529 Potency 89.1 nM
O=c1ccccn1CCOc1ccc(Cl)cc1 CHEMBL1543622 Potency 89.1 nM
CC(C)=CCN1CCN(Cc2ccc3nsnc3c2)CC1CCO CHEMBL1336843 Potency 89.1 nM
CC(OC(=O)C1CC2CCCC(C1)C2=O)C(=O)Nc1cccc([N+](=O)[O-])c1 CHEMBL1572851 Potency 89.1 nM
CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2ccc(OC)cc2)C1c1cccs1 CHEMBL1309130 Potency 89.1 nM
CC(C)c1nnc(NC(=O)c2ccc(S(=O)(=O)N3CCOCC3)cc2)s1 CHEMBL1539714 Potency 89.1 nM
CCN(Cc1ccccc1)C(=O)c1cc(S(=O)(=O)N2CCOCC2)cn1C CHEMBL1440435 Potency 89.1 nM
O=S(=O)(c1ccccc1F)N1CCc2ccccc2C1 CHEMBL1361412 Potency 89.1 nM
CCc1nnc(SCc2ccc(OC)c(Br)c2)n1N CHEMBL1375386 Potency 89.1 nM
C=CCOC(=O)CCC(=O)Nc1cc(OC)nc(OC)n1 CHEMBL1304881 Potency 89.1 nM
O=S(=O)(Nc1cccc(S(=O)(=O)N2CCOCC2)c1)c1ccc2c(c1)OCCO2 CHEMBL1482857 Potency 89.1 nM
CC(C)(C)N(CC#CCC1(O)c2ccccc2-c2ccccc21)CCO CHEMBL1426644 Potency 89.1 nM
NC(=O)c1cc[n+](CC2=C(C(=O)[O-])N3C(=O)[C@@H](NC(=O)[C@@H](c4ccccc4)S(=O)(=O)O)[C@H]3SC2)cc1 CHEMBL3351077 IC50 98.0 nM