C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 1.0 nM
CC(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F CHEMBL4592699 IC50 1.0 nM
C[C@H](N(C)c1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F CHEMBL4572019 IC50 2.0 nM
FC(F)(F)C1(Nc2nc(-c3ccncc3)nc3cnccc23)CCC1 CHEMBL4577857 IC50 2.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 3.76 nM
CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4551441 IC50 4.0 nM
Cc1n[nH]cc1-c1nc(NC2(C)CC2)c2ccncc2n1 CHEMBL4585067 IC50 4.0 nM
CC(C)(C)Nc1cc(-c2ccncc2)nc2cnccc12 CHEMBL4454440 IC50 4.0 nM
CC(N(C)c1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F CHEMBL4439529 IC50 6.0 nM
CC(C)Nc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4464251 IC50 8.0 nM
FC(F)(F)C1CN(c2nc(-c3ccncc3)nc3cnccc23)CCN1 CHEMBL4522021 IC50 8.0 nM
CC(C)(CO)Nc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4532021 IC50 11.0 nM
CC(C)(COCCO)Nc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4436873 IC50 12.0 nM
CC(C)(O)COCC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4574721 IC50 15.0 nM
CCCNc1nc(-c2c[nH]nc2C(F)(F)F)nc2cnccc12 CHEMBL4565580 IC50 15.0 nM
C[C@@H](N(C)c1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F CHEMBL4476180 IC50 18.0 nM
Cc1n[nH]c2ccc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)cc12 CHEMBL5434183 Kd 18.0 nM
CC(C)(Nc1nc(-c2ccncc2Cl)nc2cnccc12)C(F)(F)F CHEMBL4513243 IC50 20.0 nM
CC(C)(O)CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4533967 IC50 21.0 nM
c1cc(-c2nc(NC3CCCC3)c3ccncc3n2)ccn1 CHEMBL4547445 IC50 30.0 nM
OCC1(Nc2nc(-c3ccncc3)nc3cnccc23)CCC1 CHEMBL4529548 IC50 30.0 nM
FC(F)(F)C1(Nc2nc(-c3ccncc3)cc3cnccc23)CC1 CHEMBL4449036 IC50 34.0 nM
Cc1n[nH]c2ccc(-c3nnc(C)n3Cc3ccc(Cl)cc3)cc12 CHEMBL5414359 Kd 38.0 nM
CCCNc1nc(-c2ccncc2)nc2cnccc12 CHEMBL4472817 IC50 50.0 nM
Cn1nccc1-c1nc(NC2(C)CCC2)c2ccncc2n1 CHEMBL4534258 IC50 50.0 nM
C[C@@H](NC(=O)Nc1cc2[nH]ncc2c(CO)n1)c1ccccc1 CHEMBL4538174 Kd 55.0 nM
Cn1cncc1C1=CN(c2ncnc3[nH]cnc23)CCS1 CHEMBL5433617 IC50 70.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 135.0 nM
CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21 CHEMBL494089 Kd 140.0 nM
CC(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F CHEMBL4571192 IC50 170.0 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 223.0 nM
Cc1n[nH]c2ccc(-c3nnc(C)n3Cc3ccc(C(F)(F)F)cc3)cc12 CHEMBL5396725 Kd 250.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL502835 Kd 380.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 430.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 460.0 nM
Cc1n[nH]c2ccc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)nc12 CHEMBL5416758 Kd 460.0 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 Kd 530.0 nM
Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 CHEMBL379218 Kd 620.0 nM
CN(C)C[C@@H]1CCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCO1 CHEMBL91829 Kd 640.0 nM
CC(C)C[C@](C)(N)COc1ccc(-c2ccnc(C(F)F)c2)nc1C(F)F CHEMBL5089410 IC50 660.0 nM
Cc1n[nH]c2ncc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)cc12 CHEMBL5425043 Kd 730.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM