COCCS(=O)(=O)C(C(=O)NCc1cc(C)no1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677564 IC50 0.5 nM
CC(C)(C)OC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL3677604 IC50 0.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(Cl)c3)cc2s1 CHEMBL3677538 IC50 0.8 nM
COCCS(=O)(=O)C(C(=O)NCc1cc(C(C)C)no1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677562 IC50 0.8 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(NC(=O)OCc4ccccc4)cc3)cc2s1 CHEMBL4460999 IC50 0.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3F)cc2s1 CHEMBL3677630 IC50 1.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(N4CCCC4)c3)cc2s1 CHEMBL3672652 IC50 1.0 nM
CC(C)c1cc(CNC(=O)C(c2nc3ccc(-c4ccccc4)cc3s2)S(C)(=O)=O)on1 CHEMBL3677580 IC50 1.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3F)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677632 IC50 1.5 nM
COCCOC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672654 IC50 1.9 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(Oc4ccccc4)c3)cc2s1 CHEMBL3677540 IC50 1.9 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4463265 IC50 2.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3F)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682478 IC50 2.1 nM
COc1cc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)ccn1 CHEMBL3677434 IC50 2.2 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(Cl)c3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677571 IC50 2.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677610 IC50 2.6 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672653 IC50 2.6 nM
COc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cn1 CHEMBL3677433 IC50 2.6 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(C(=O)OC(C)(C)C)cc4)cc3s2)S(C)(=O)=O)s1 CHEMBL3677607 IC50 2.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(Cl)cc3)cc2s1 CHEMBL3677537 IC50 2.8 nM
CC(C)(C)OC(=O)n1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1 CHEMBL3677550 IC50 2.8 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2c(F)cc(-c3cccc(C(=O)OC(C)(C)C)c3)cc2s1 CHEMBL3677608 IC50 2.9 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(OC(F)F)c3)cc2s1 CHEMBL3677543 IC50 3.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)OC(C)(C)C)cc1 CHEMBL3677601 IC50 3.0 nM
CN(Cc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1)S(N)(=O)=O CHEMBL3890635 IC50 3.0 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O CHEMBL175247 IC50 3.0 nM
Cc1cc(CNC(=O)C(c2nc3ccc(-c4ccccc4)cc3s2)S(C)(=O)=O)on1 CHEMBL3677563 IC50 3.6 nM
COCc1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1 CHEMBL3677545 IC50 3.6 nM
CC(C)Oc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1Cl CHEMBL3677547 IC50 3.6 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(C(=O)NCC(F)(F)F)cc3s2)o1 CHEMBL4465833 IC50 4.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(-c4ccc(C(=O)NCC(F)(F)F)cc4)c(F)cc3s2)o1 CHEMBL4460376 IC50 4.0 nM
COC(=O)Nc1ccc(-c2ccc3nc(C(=O)c4nnc(CNS(N)(=O)=O)o4)sc3c2)cc1 CHEMBL3905549 IC50 5.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)OC(C)(C)C)cc1 CHEMBL3677602 IC50 5.1 nM
COc1c(F)cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F CHEMBL3677548 IC50 5.2 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4587475 IC50 5.4 nM
COCc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3682490 IC50 6.7 nM
O=C(CNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)Cc1ccccc1)NC1CC1 CHEMBL4437751 IC50 7.0 nM
COCCNC(=O)c1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3677439 IC50 7.1 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677567 IC50 7.3 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(-c4nnc(N)s4)cc3)cc2s1 CHEMBL3677553 IC50 7.7 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(-c4ccc(F)nc4)cc3s2)o1 CHEMBL4471611 IC50 9.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(F)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677581 IC50 9.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)CC1CC1 CHEMBL3677462 IC50 10.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(OCCN4CCOCC4)cc3)cc2s1 CHEMBL3672632 IC50 10.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(-c4ncco4)cc3)cc2s1 CHEMBL3677554 IC50 10.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccc(F)cc4)cc3s2)o1 CHEMBL3982030 IC50 10.0 nM
CNS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4446812 IC50 10.0 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccc(Cl)c(Cl)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4440746 IC50 10.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(F)c(-c3ccccc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677480 IC50 11.0 nM
COc1ccc(CN(Cc2ccc(OC)cc2)S(=O)(=O)CCNC(=O)C(c2nc3ccc(-c4ccccc4)cc3s2)S(C)(=O)=O)cc1 CHEMBL3677465 IC50 11.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(F)c(-c4ccccc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677498 IC50 11.0 nM
COCCOc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672638 IC50 11.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677463 IC50 11.0 nM
COC(C)(C)CNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677572 IC50 12.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC(C)C)sc2cc1-c1ccc(F)nc1 CHEMBL3677475 IC50 12.0 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccnc(OC)c3)cc2s1 CHEMBL3677492 IC50 13.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cccnc3F)ccc2s1 CHEMBL3682495 IC50 13.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc2cc1-c1ccc(F)nc1 CHEMBL3677474 IC50 13.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccnc(O)c3)cc2s1 CHEMBL3677525 IC50 13.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccccc3F)ccc2s1 CHEMBL3682466 IC50 13.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cc(F)cc(Cl)c3)cc2s1 CHEMBL3677539 IC50 13.9 nM
[C-]#[N+]c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672640 IC50 14.0 nM
CC(C)(C)OC(=O)c1ccc(-c2ccc3nc(C(C(=O)N[C@@H]4CCNC4=O)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL3682498 IC50 14.3 nM
CS(=O)(=O)C(C(=O)NCc1cccc(S(N)(=O)=O)c1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677584 IC50 14.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCCC(F)(F)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682449 IC50 14.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCCCC4)cc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3682465 IC50 14.9 nM
N#Cc1cccc(CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c2nc3ccc(-c4ccccc4)cc3s2)c1 CHEMBL3677464 IC50 15.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4520847 IC50 15.0 nM
Cc1nnc(-c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cc2)o1 CHEMBL3677555 IC50 15.4 nM
COCCOc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3682482 IC50 15.5 nM
Cn1ccc(C(=O)NCCCc2ccc(Cl)c(Cl)c2)c(O)c1=O CHEMBL4212095 IC50 16.0 nM
CO[C@H]1CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)cc2)C1 CHEMBL3677629 IC50 16.6 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NCC(F)(F)F)cc3)cc2s1 CHEMBL3672631 IC50 17.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677535 IC50 17.5 nM
COCC(C)(C)NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677576 IC50 17.6 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2c(F)cc(-c3ccccc3)cc2s1 CHEMBL3677478 IC50 18.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cccc(F)n3)ccc2s1 CHEMBL3682492 IC50 18.5 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(F)cc5)sc4c3)cc2)C1 CHEMBL3682467 IC50 18.5 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCc4cc(C(C)C)no4)S(C)(=O)=O)sc3c2)cc1 CHEMBL3677561 IC50 18.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NCCO)cc3)cc2s1 CHEMBL3672630 IC50 19.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCC(F)(F)CC4)cc3)cc2s1 CHEMBL3677512 IC50 19.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(F)c(-c3ccccc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677503 IC50 20.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccc(F)nc4)cc3s2)o1 CHEMBL4475891 IC50 20.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(-c4ccc5c(c4)CNC5=O)cc3s2)o1 CHEMBL4460663 IC50 20.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(-c4ccc5c(c4)CNC5=O)c(F)cc3s2)o1 CHEMBL4581886 IC50 20.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3F)ccc2s1 CHEMBL3682497 IC50 20.5 nM
CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cn2)CC1 CHEMBL3672666 IC50 21.0 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccccc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4468090 IC50 21.0 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677615 IC50 21.7 nM
Cc1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cnc1F CHEMBL3672623 IC50 22.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2c(F)cc(-c3ccccc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677477 IC50 22.0 nM
NCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677504 IC50 22.0 nM
NCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677502 IC50 22.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC[C@H](O)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682458 IC50 22.2 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC(F)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682450 IC50 22.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(OCCN4CCOCC4)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3672644 IC50 23.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677452 IC50 23.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ncccn3)ccc2s1 CHEMBL3682486 IC50 23.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(-c3ccc(F)nc3)ccc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677636 IC50 24.2 nM
CO[C@H]1CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682470 IC50 26.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)NC4CCC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682451 IC50 28.4 nM
COCC(C)(C)NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677577 IC50 29.4 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccc5c(c4)C(=O)NC5)cc3s2)o1 CHEMBL4575712 IC50 30.0 nM
C[C@H](NS(N)(=O)=O)c1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3896109 IC50 30.0 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(N)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682476 IC50 30.3 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)CCNC(=O)OCc1ccccc1 CHEMBL3677501 IC50 31.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cncs3)cc2s1 CHEMBL3677552 IC50 31.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCC(F)(F)C4)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677511 IC50 32.0 nM
COc1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)ccn1 CHEMBL3677488 IC50 33.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(CCO)cc3)cc2s1 CHEMBL3672637 IC50 35.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3cccc(C(=O)N4CCCCC4)c3)cc2s1 CHEMBL4581408 IC50 35.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CO)cc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677639 IC50 35.1 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677617 IC50 35.2 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1 CHEMBL3677519 IC50 36.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(CCO)c3)cc2s1 CHEMBL3672648 IC50 36.0 nM
CC(C)(C)OC(=O)N1CC=C(c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)CC1 CHEMBL3682494 IC50 36.5 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)N2CCCCC2)cc1 CHEMBL3682462 IC50 37.1 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(C(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682436 IC50 37.4 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1F CHEMBL3677560 IC50 37.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NCC(F)(F)F)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3672635 IC50 38.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCC(F)(F)CC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682457 IC50 38.1 nM
COC[C@H](C)NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677578 IC50 38.4 nM
Cc1nnc(CNC(=O)C(c2nc3cc(F)c(-c4ccccc4)cc3s2)S(=O)(=O)CC(C)C)o1 CHEMBL3677496 IC50 39.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(F)c(-c4ccccc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677497 IC50 39.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(-c4ccc(C(=O)N5CCOCC5)c(F)c4)cc3s2)o1 CHEMBL4563019 IC50 40.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccncc3F)ccc2s1 CHEMBL3682493 IC50 40.2 nM
CC(C)Cn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cn1 CHEMBL3672657 IC50 41.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672625 IC50 43.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4cccc(N(C)C)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677583 IC50 43.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cnoc3)ccc2s1 CHEMBL3682485 IC50 45.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC(F)C4)cc3)cc2s1 CHEMBL3682444 IC50 46.7 nM
CCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccccc3)cc2s1 CHEMBL3677495 IC50 47.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)cc2s1)S(=O)(=O)Cc1cccc(C(F)(F)F)c1 CHEMBL3682473 IC50 47.0 nM
CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4528020 IC50 47.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677457 IC50 48.2 nM
CC(F)(F)CNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682453 IC50 49.2 nM
CN1CCOc2cc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)ccc21 CHEMBL3672651 IC50 50.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(F)c3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677470 IC50 51.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677628 IC50 51.2 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(-c3ccc(F)nc3)ccc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677635 IC50 51.4 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(F)cc5)sc4c3)cc2)C1 CHEMBL3677627 IC50 52.0 nM
CS(=O)(=O)C(C(=O)NCCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4438013 IC50 52.0 nM
CC1(Cc2nnc(C(c3nc4ccc(-c5ccccc5)cc4s3)S(C)(=O)=O)o2)NC(=O)NC1=O CHEMBL4536805 IC50 53.0 nM
CS(=O)(=O)C(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4471545 IC50 53.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(C(=O)N5CC(F)(F)C5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677585 IC50 53.3 nM
CC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3672645 IC50 55.0 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677612 IC50 55.5 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(F)c(-c3ccccc3)cc2s1)S(=O)(=O)CCNCc1ccccc1 CHEMBL3677479 IC50 56.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NCCCO)cc3)cc2s1 CHEMBL3677541 IC50 57.0 nM
COc1ccc(-c2cc3sc(C(C(=O)NCc4nnc(C)o4)S(=O)(=O)Cc4ccccc4)nc3cc2C)cn1 CHEMBL3677443 IC50 57.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCC(F)(F)C4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682438 IC50 58.1 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCC(F)(F)C4)cc3)cc2s1 CHEMBL3677509 IC50 60.0 nM
C[C@@H](NS(N)(=O)=O)c1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4114591 IC50 60.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC(F)(F)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682448 IC50 60.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CCO)cc3)cc2s1)S(=O)(=O)CC1CC1 CHEMBL3672650 IC50 61.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NCC(F)(F)F)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3672655 IC50 61.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677445 IC50 63.0 nM
COc1nccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1F CHEMBL3677493 IC50 64.0 nM
COc1ncccc1-c1ccc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2c1 CHEMBL3677521 IC50 65.0 nM
CC(=O)Nc1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1 CHEMBL3672642 IC50 66.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(-c3ccc(F)nc3)ccc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677634 IC50 67.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1)S(=O)(=O)Cc1ccc(C(F)(F)F)cc1 CHEMBL3682472 IC50 67.6 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3c[nH]nc3C(F)(F)F)cc2s1 CHEMBL3672668 IC50 68.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(F)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3672662 IC50 68.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccnc(F)c3)ccc2s1 CHEMBL3677441 IC50 70.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cncnc3)ccc2s1 CHEMBL3677435 IC50 70.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1 CHEMBL4541404 IC50 70.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NC4CC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677556 IC50 74.0 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(C(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3677625 IC50 74.2 nM
CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL4207216 IC50 76.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CCO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677568 IC50 76.6 nM
COc1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c(F)cn1 CHEMBL3677486 IC50 77.0 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)cc2s1 CHEMBL3677508 IC50 79.0 nM
O=C(CNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)CCC(F)(F)F)NC1CC1 CHEMBL4523021 IC50 79.0 nM
CN(C)C(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682454 IC50 79.5 nM
NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677557 IC50 80.8 nM
CS(=O)(=O)C(C(=O)NCCNS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4461739 IC50 81.0 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682437 IC50 81.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cncc(F)c3)ccc2s1 CHEMBL3682489 IC50 82.1 nM
CC(=O)Nc1cccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)c1 CHEMBL3682491 IC50 83.7 nM
Cc1nnc(CNC(=O)C(c2nc3cc(F)c(-c4ccccc4)cc3s2)S(=O)(=O)CCC(F)(F)F)o1 CHEMBL3677494 IC50 84.0 nM
NS(=O)(=O)c1ccccc1CNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677605 IC50 84.9 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3677626 IC50 85.1 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F CHEMBL3677542 IC50 87.9 nM
CC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677613 IC50 90.0 nM
COC(=O)Nc1ccc(-c2ccc3nc(C(c4nnc(CNS(N)(=O)=O)o4)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL4473964 IC50 90.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)N2CCOCC2)cc1 CHEMBL3682464 IC50 90.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCC(F)(F)C4)cc3)cc2s1 CHEMBL3677510 IC50 91.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NC4COC4)cc3)cc2s1 CHEMBL3677516 IC50 91.0 nM
CC1(O)CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cc2)CC1 CHEMBL3677514 IC50 92.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)cc2s1)S(=O)(=O)Cc1ccc(C(F)(F)F)cc1 CHEMBL3682471 IC50 93.2 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F CHEMBL3677574 IC50 94.4 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccnc(O)c3)ccc2s1 CHEMBL3677529 IC50 95.0 nM
CC(=O)Nc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3682483 IC50 96.3 nM
CN(CC(F)F)C(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682452 IC50 99.7 nM
COCCn1cc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cn1 CHEMBL3677436 IC50 100.0 nM
COC(=O)CCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677536 IC50 100.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NCCO)cc3)cc2s1)S(=O)(=O)CC1CC1 CHEMBL3672649 IC50 102.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NCCO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3672656 IC50 103.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)O)cc1 CHEMBL3682439 IC50 104.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(O)nc3)ccc2s1 CHEMBL3677530 IC50 105.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677638 IC50 106.5 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cccc(C#N)c4)sc3c2)cc1 CHEMBL3677459 IC50 107.0 nM
CC(C)(O)CNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(F)cc4)sc3c2)cc1 CHEMBL3677570 IC50 109.3 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL3677609 IC50 109.7 nM
CC1(O)CCN(C(=O)c2cccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)c2)CC1 CHEMBL3682455 IC50 111.8 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(Cl)c(Cl)c4)sc3c2)cc1 CHEMBL3677618 IC50 112.0 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)cc2)C1 CHEMBL3639764 IC50 112.9 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677616 IC50 114.5 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cc2)C1 CHEMBL3677513 IC50 118.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677458 IC50 119.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCOCC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682447 IC50 119.3 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccc(C(=O)N5CCOCC5)c(Cl)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4435864 IC50 121.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(CO)cc3)cc2s1 CHEMBL3672646 IC50 122.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(C(=O)NCCO)cc3)ccc2s1 CHEMBL3677440 IC50 123.0 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677614 IC50 123.5 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc5c(c4)CCC(=O)N5)cc3s2)S(C)(=O)=O)o1 CHEMBL3677431 IC50 124.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3)ccc2s1 CHEMBL3682484 IC50 124.2 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677611 IC50 126.4 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1F CHEMBL3677575 IC50 127.3 nM
CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4458992 IC50 130.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677573 IC50 130.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCC(O)CC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682446 IC50 136.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc4c(c3)NC(=O)C4)cc2s1 CHEMBL3677520 IC50 139.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cc(Cl)cc(Cl)c4)sc3c2)cc1 CHEMBL3677621 IC50 140.4 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(S(N)(=O)=O)c3)cc2s1 CHEMBL3677549 IC50 141.8 nM
Cn1cc(-c2cc3sc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccccc4)nc3cc2F)cn1 CHEMBL3677482 IC50 142.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(S(=O)(=O)NCCO)cc3)cc2s1 CHEMBL3672647 IC50 144.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc4c(c3)C(=O)NC4)cc2s1 CHEMBL3677518 IC50 145.0 nM
CC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL3672634 IC50 148.0 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC[C@H](OC)C4)cc3)cc2s1 CHEMBL3677631 IC50 149.3 nM
COCCNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1 CHEMBL3672639 IC50 152.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CCO)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3672643 IC50 152.0 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3)ccc2s1 CHEMBL3677637 IC50 152.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC[C@@H](O)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682456 IC50 153.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NC4CC4)cc3)cc2s1 CHEMBL3677546 IC50 154.9 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(N)=O)cc3)cc2s1 CHEMBL3677544 IC50 159.9 nM
COCCNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3677517 IC50 170.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(C(=O)N4CCC4)cc3)cc2s1 CHEMBL4557646 IC50 170.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)ccc2s1 CHEMBL3677646 IC50 175.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cccc(F)c4)sc3c2)cc1 CHEMBL3677461 IC50 176.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccccc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3639762 IC50 177.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677454 IC50 180.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677620 IC50 180.7 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677460 IC50 182.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCc4nnc(C)o4)S(=O)(=O)CCOC)sc3c2)cc1 CHEMBL3677592 IC50 184.5 nM
N#CC(C(=O)NCC(=O)NC1COC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4446981 IC50 190.0 nM
CC(C)CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677453 IC50 191.0 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3)ccc2s1 CHEMBL3677633 IC50 194.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(C(=O)N5CCOCC5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677428 IC50 196.0 nM
COCCn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c(C(F)(F)F)n1 CHEMBL3677506 IC50 199.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)O)cc1 CHEMBL3682440 IC50 201.4 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N(C)C)c(F)c3)cc2s1 CHEMBL3677587 IC50 207.7 nM
COCCS(=O)(=O)NS(=O)(=O)c1cccc(CNC(=O)C(c2nc3cc(-c4ccccc4)ccc3s2)S(=O)(=O)CCOC)c1 CHEMBL3677598 IC50 211.9 nM
CC(C)(O)CNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682459 IC50 213.0 nM
NC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682445 IC50 214.2 nM
CS(=O)(=O)C(C(=O)NCc1ccccc1S(N)(=O)=O)c1nc2ccc(-c3ccc(N4CCCCC4)cc3)cc2s1 CHEMBL3677603 IC50 218.5 nM
Cn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cccc(C(F)(F)F)c4)sc3c2)ccc1=O CHEMBL3682479 IC50 219.1 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4cnn(CCN5CCOCC5)c4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677429 IC50 229.0 nM
COCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4514272 IC50 230.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(S(=O)(=O)NCCO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677566 IC50 233.8 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CC(F)C4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682469 IC50 235.2 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccnc(O)c3F)cc2s1 CHEMBL3677528 IC50 238.0 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1F CHEMBL3677559 IC50 242.3 nM
NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677558 IC50 249.6 nM
N#CC(C(=O)NCC(=O)N1CCCC1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4562731 IC50 250.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(C(=O)N5CCOCC5)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677442 IC50 251.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(O)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677582 IC50 259.3 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC[C@@H](O)C4)cc3)cc2s1 CHEMBL3682443 IC50 261.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677622 IC50 266.7 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccnc(O)c3)cc2s1 CHEMBL3677526 IC50 272.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)C(C)C)sc3c2)cc1 CHEMBL3677595 IC50 289.0 nM
Cc1cc2nc(C(C(=O)NCCS(=O)(=O)NS(C)(=O)=O)S(C)(=O)=O)sc2cc1-c1cnn(C)c1 CHEMBL3677472 IC50 290.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(Br)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677469 IC50 300.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL4545633 IC50 300.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCC(F)(F)F)c3)cc2s1 CHEMBL3677551 IC50 308.1 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1 CHEMBL3672624 IC50 310.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(C(=O)N3CCc4ccccc4C3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677534 IC50 311.0 nM
COCCNC(=O)c1ccc(-c2cc3sc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)C(C)C)nc3cc2C(F)(F)F)cc1 CHEMBL3677597 IC50 312.1 nM
COCCn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cn1 CHEMBL3677507 IC50 317.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(C(F)(F)F)cc1 CHEMBL3677619 IC50 328.5 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)N2CC(C)(O)C2)cc1 CHEMBL3682463 IC50 347.2 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(N5CCNCC5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677430 IC50 350.0 nM
NS(=O)(=O)c1cccc(CNC(=O)C(c2nc3ccc(-c4ccncc4Cl)cc3s2)S(=O)(=O)Cc2ccccc2)c1 CHEMBL3677606 IC50 355.1 nM
Cn1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1=O CHEMBL3677489 IC50 362.0 nM
C[C@H]1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC5CC5)sc4c3)cc2)CCO1 CHEMBL3677579 IC50 362.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)CC1CC1 CHEMBL3677455 IC50 364.6 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N4CCCC4)cc3)cc2s1 CHEMBL3677590 IC50 373.7 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(c4nnc(CNS(N)(=O)=O)o4)S(=O)(=O)Cc4ccccc4)sc3c2)cc1Cl CHEMBL4577903 IC50 391.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCC4CCOCC4)c3)cc2s1 CHEMBL3677642 IC50 391.3 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(O)n3)cc2s1 CHEMBL3677524 IC50 398.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(F)(F)F)nc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677641 IC50 399.1 nM
CC(C)CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1 CHEMBL3677467 IC50 400.0 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)N2CCOCC2)cc1 CHEMBL3682460 IC50 400.4 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(C(F)(F)F)c(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677596 IC50 405.8 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)C(C)C)sc2cc1-c1ccc(F)nc1 CHEMBL3677476 IC50 411.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc4c(c3)C(=O)NC4)cc2s1 CHEMBL4553622 IC50 420.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(O)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677527 IC50 445.0 nM
CS(=O)(=O)C(c1nnc(CC2SC(=O)NC2=O)o1)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL4563513 IC50 450.0 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5cccc(C(F)(F)F)c5)sc4c3)cc2)C1 CHEMBL3682474 IC50 471.4 nM
CN1CCN(C(=O)c2ccc(-c3ccc4nc(C(C#N)C(=O)NCC(=O)NC5CCC5)sc4c3)cc2)CC1 CHEMBL4544715 IC50 490.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(C(=O)N4CCOCC4)cc3)ccc2s1 CHEMBL3677432 IC50 494.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCC(O)CC4)cc3)cc2s1 CHEMBL3677515 IC50 495.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4459874 IC50 500.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NCCO)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3672636 IC50 520.0 nM
CO[C@@H]1CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682468 IC50 552.8 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(Cl)c(Cl)c1 CHEMBL3677623 IC50 555.7 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)N2CC(C)(O)C2)cc1 CHEMBL3682461 IC50 579.6 nM
CC(C)(O)CNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3677569 IC50 607.0 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(C(=O)N(C)C)c3)cc2s1 CHEMBL3677600 IC50 611.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3672659 IC50 612.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677466 IC50 631.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2ccc(-c3ccc(C(=O)N4CC(C)(O)C4)cc3)cc2s1 CHEMBL3677593 IC50 634.0 nM
CN(C)C(=O)c1cccc(-c2ccc3nc(C(C#N)C(=O)NCC(=O)NC4CC4)sc3c2)c1 CHEMBL4557424 IC50 720.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N4CCCC4)c(F)c3)cc2s1 CHEMBL3677589 IC50 764.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(O)c3F)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682487 IC50 786.9 nM
Cn1nccc1-c1ccc2sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc2c1 CHEMBL3682496 IC50 827.6 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(Br)cc2s1 CHEMBL3677468 IC50 830.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ncccn3)cc2s1 CHEMBL3677624 IC50 865.7 nM
COCCNC(=O)c1ccc(-c2cc3sc(C(C(=O)NCc4nnc(C)o4)S(=O)(=O)CCOC)nc3cc2F)cc1 CHEMBL3677586 IC50 888.7 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cc2)C1 CHEMBL3677643 IC50 910.9 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cncnc3)cc2s1 CHEMBL3677490 IC50 916.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)c(Cl)c3)cc2s1 CHEMBL3672622 IC50 923.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1)S(=O)(=O)CCCC(F)(F)F CHEMBL3677471 IC50 933.0 nM
COCCNC(=O)c1ccc(-c2cc3sc(C(C(=O)NCc4nnc(C)o4)S(C)(=O)=O)nc3cc2F)cc1 CHEMBL3677594 IC50 947.5 nM