COc1cc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)ccn1 CHEMBL3677434 IC50 0.5 nM
CC(=O)Nc1cccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)c1 CHEMBL3682491 IC50 0.5 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NC4CC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677556 IC50 0.5 nM
COCCOC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672654 IC50 0.5 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(-c3ccc(F)nc3)ccc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677634 IC50 0.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccnc(O)c3F)cc2s1 CHEMBL3677528 IC50 0.5 nM
NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677557 IC50 0.5 nM
COc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cn1 CHEMBL3677433 IC50 0.5 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672653 IC50 0.5 nM
COCCNC(=O)c1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3677439 IC50 0.5 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(-c4ccc5c(c4)CNC5=O)cc3s2)o1 CHEMBL4460663 IC50 0.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(Oc4ccccc4)c3)cc2s1 CHEMBL3677540 IC50 0.6 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)ccc2s1 CHEMBL3677646 IC50 0.6 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677617 IC50 0.7 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677457 IC50 0.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC(F)C4)cc3)cc2s1 CHEMBL3682444 IC50 0.7 nM
COCc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3682490 IC50 0.7 nM
CO[C@H]1CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)cc2)C1 CHEMBL3677629 IC50 0.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cccnc3F)ccc2s1 CHEMBL3682495 IC50 0.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NCCCO)cc3)cc2s1 CHEMBL3677541 IC50 0.7 nM
CC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3672645 IC50 0.8 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677458 IC50 0.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(Cl)c3)cc2s1 CHEMBL3677538 IC50 0.8 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677614 IC50 0.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ncccn3)ccc2s1 CHEMBL3682486 IC50 0.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccccc3F)ccc2s1 CHEMBL3682466 IC50 0.8 nM
COC(C)(C)CNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677572 IC50 0.9 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(-c4ccc(C(=O)N5CCOCC5)c(F)c4)cc3s2)o1 CHEMBL4563019 IC50 0.9 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)N2CCCCC2)cc1 CHEMBL3682462 IC50 1.0 nM
CC(C)(O)CNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682459 IC50 1.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(O)nc3)ccc2s1 CHEMBL3677530 IC50 1.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(-c3ccc(F)nc3)ccc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677635 IC50 1.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(-c4ccc(F)nc4)cc3s2)o1 CHEMBL4471611 IC50 1.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(NC(=O)OCc4ccccc4)cc3)cc2s1 CHEMBL4460999 IC50 1.0 nM
CC(C)(O)Cn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)ccc1=O CHEMBL3677523 IC50 1.1 nM
CC(C)(C)OC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL3677604 IC50 1.1 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccncc3F)ccc2s1 CHEMBL3682493 IC50 1.1 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)O)cc1 CHEMBL3682439 IC50 1.2 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F CHEMBL3677542 IC50 1.2 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(-c4nnc(N)s4)cc3)cc2s1 CHEMBL3677553 IC50 1.2 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(N4CCCC4)c3)cc2s1 CHEMBL3672652 IC50 1.2 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cccc(C#N)c4)sc3c2)cc1 CHEMBL3677459 IC50 1.2 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3)ccc2s1 CHEMBL3677633 IC50 1.3 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)OC(C)(C)C)cc1 CHEMBL3677601 IC50 1.4 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(Cl)cc3)cc2s1 CHEMBL3677537 IC50 1.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCC(O)CC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682446 IC50 1.5 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccnc(F)c3)ccc2s1 CHEMBL3677441 IC50 1.5 nM
CC(C)OCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3945066 IC50 1.598 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)O)cc1 CHEMBL3682440 IC50 1.6 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(N)=O)cc3)cc2s1 CHEMBL3677544 IC50 1.6 nM
COc1c(F)cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F CHEMBL3677548 IC50 1.7 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)OC(C)(C)C)cc1 CHEMBL3677602 IC50 1.7 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC[C@@H](O)C4)cc3)cc2s1 CHEMBL3682443 IC50 1.8 nM
COCCOc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3682482 IC50 1.8 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cc2)C1 CHEMBL3677643 IC50 1.8 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)cc2)C1 CHEMBL3677645 IC50 1.9 nM
CC(C)(O)Cn1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1=O CHEMBL3682500 IC50 2.0 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(F)cc5)sc4c3)cc2)C1 CHEMBL3682467 IC50 2.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccnc(O)c3)ccc2s1 CHEMBL3677529 IC50 2.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cccc(F)n3)ccc2s1 CHEMBL3682492 IC50 2.0 nM
CC(C#N)NC(=O)Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3680965 IC50 2.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)NC4CC4)cc3)cc2s1 CHEMBL3677546 IC50 2.1 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677573 IC50 2.1 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(S(N)(=O)=O)c3)cc2s1 CHEMBL3677549 IC50 2.2 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)N2CC(C)(O)C2)cc1 CHEMBL3682463 IC50 2.3 nM
CC(C)Oc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1Cl CHEMBL3677547 IC50 2.3 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(C(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682436 IC50 2.4 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3)ccc2s1 CHEMBL3682484 IC50 2.5 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677628 IC50 2.5 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682437 IC50 2.6 nM
C[C@H]1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC5CC5)sc4c3)cc2)CCO1 CHEMBL3677579 IC50 2.6 nM
CC(C)(O)CNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(F)cc4)sc3c2)cc1 CHEMBL3677570 IC50 2.7 nM
CO[C@H]1CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682470 IC50 2.7 nM
CC(C)CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3945247 IC50 2.71 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F CHEMBL3677574 IC50 2.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(OC(F)F)c3)cc2s1 CHEMBL3677543 IC50 2.8 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677622 IC50 2.9 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cncc(F)c3)ccc2s1 CHEMBL3682489 IC50 2.9 nM
CC(C)CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3900325 IC50 2.932 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)O)cc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3682441 IC50 3.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3F)cc2s1 CHEMBL3677630 IC50 3.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3F)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677632 IC50 3.0 nM
CC(=O)Nc1ccc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)cc1 CHEMBL3682483 IC50 3.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2cc(-c3ccc(F)nc3)ccc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677636 IC50 3.1 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677615 IC50 3.1 nM
CC(C)(C)OC(=O)N1CC=C(c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)CC1 CHEMBL3682494 IC50 3.1 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2cc1-c1ccc(C(=O)N2CCOCC2)cc1 CHEMBL3682464 IC50 3.2 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(CCc2ccccc2)C1 CHEMBL3948143 IC50 3.216 nM
CCCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3960312 IC50 3.255 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cnoc3)ccc2s1 CHEMBL3682485 IC50 3.3 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2cccc(Cl)c2)C1 CHEMBL3957867 IC50 3.304 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)N2CC(C)(O)C2)cc1 CHEMBL3682461 IC50 3.4 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3F)ccc2s1 CHEMBL3682497 IC50 3.5 nM
CC(C)(O)Cn1cc(-c2ccc3sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc3c2)ccc1=O CHEMBL3682501 IC50 3.5 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2ccccc2)C1 CHEMBL3890131 IC50 3.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)NCCO)cc3)cc2s1)S(=O)(=O)CC1CC1 CHEMBL3672649 IC50 3.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1)S(=O)(=O)Cc1ccc(C(F)(F)F)cc1 CHEMBL3682472 IC50 3.7 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC[C@H](OC)C4)cc3)cc2s1 CHEMBL3677631 IC50 3.8 nM
CO[C@@H]1CCN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682468 IC50 3.8 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677612 IC50 3.9 nM
Nc1cc2c3c(c1)c(C(F)(F)F)c(CCCc1ccccc1)n3CCC2 CHEMBL3092451 IC50 4.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CC[C@H](O)C4)cc3)cc2s1 CHEMBL3682442 IC50 4.0 nM
Cn1cc(-c2ccc3sc(Cc4nnc(CC(=O)NC5(C#N)CC5)o4)nc3c2)cn1 CHEMBL3680958 IC50 4.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ccc(Cl)s5)cc4s3)o2)CC1 CHEMBL3680968 IC50 4.0 nM
Nc1cc2c3c(c1)c(C(F)(F)F)c(CCCOc1ccccc1)n3CCC2 CHEMBL3924236 IC50 4.0 nM
Cn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cccc(C(F)(F)F)c4)sc3c2)ccc1=O CHEMBL3682479 IC50 4.4 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3cncnc3)ccc2s1 CHEMBL3677435 IC50 4.4 nM
COCc1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1 CHEMBL3677545 IC50 4.4 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1F CHEMBL3677560 IC50 4.6 nM
COCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4514272 IC50 4.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)cc2s1)S(=O)(=O)Cc1cccc(C(F)(F)F)c1 CHEMBL3682473 IC50 4.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(Cl)c3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677571 IC50 4.8 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2c(F)cc(-c3cccc(C(=O)OC(C)(C)C)c3)cc2s1 CHEMBL3677608 IC50 4.8 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc4c3)cc2)C1 CHEMBL3677644 IC50 4.8 nM
CC(C)(C)CN1CC(c2nnc(C(=O)c3nc4ccc(-c5ccc(F)cc5)cc4s3)o2)C1 CHEMBL3897447 IC50 4.8 nM
COCCS(=O)(=O)C(C(=O)NCc1cc(C)no1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677564 IC50 4.9 nM
Cc1nnc(-c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc4c3)cc2)o1 CHEMBL3677555 IC50 4.9 nM
NS(=O)(=O)NCc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3680951 IC50 5.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4463265 IC50 5.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL3672598 IC50 5.0 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(C2CCC2)C1 CHEMBL3962684 IC50 5.095 nM
Cn1nccc1-c1ccc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2c1 CHEMBL3677565 IC50 5.1 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(CCc2ccccc2Cl)C1 CHEMBL3912458 IC50 5.239 nM
CC(C)(O)Cn1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1=O CHEMBL3682499 IC50 5.3 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(Cl)c(Cl)c1 CHEMBL3677623 IC50 5.3 nM
Cc1cc2nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc3ccccc3)sc2cc1-c1ccc(C(=O)N2CCOCC2)cc1 CHEMBL3682460 IC50 5.3 nM
COC[C@H](C)NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677578 IC50 5.3 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1 CHEMBL4541404 IC50 5.3 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677611 IC50 5.4 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(CCOc2ccccc2)C1 CHEMBL4203395 IC50 5.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCCC(F)(F)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682449 IC50 5.5 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3677626 IC50 5.5 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2ccc(F)cc2)C1 CHEMBL3945671 IC50 5.522 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(C(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3677625 IC50 5.6 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(CCc2ccc(F)cc2)C1 CHEMBL3906585 IC50 5.607 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2cc(Cl)cc(Cl)c2)C1 CHEMBL3961323 IC50 5.637 nM
CC(C)(C)CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3972915 IC50 5.803 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2cccc(F)c2)C1 CHEMBL3955903 IC50 5.99 nM
CC1(O)CCN(C(=O)c2cccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)c2)CC1 CHEMBL3682455 IC50 6.0 nM
O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)Nc1ccccc1 CHEMBL3680950 IC50 6.0 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O CHEMBL175247 IC50 6.0 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1F CHEMBL3677575 IC50 6.1 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCCCC4)cc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3682465 IC50 6.2 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(-c3ccc(F)nc3)ccc2s1 CHEMBL3677637 IC50 6.2 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5cccc(C(F)(F)F)c5)sc4c3)cc2)C1 CHEMBL3682474 IC50 6.2 nM
CCOCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3905975 IC50 6.3 nM
CC(C)(O)CNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3677569 IC50 6.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CC(F)C4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682469 IC50 6.6 nM
O=C(c1nnc(NCCc2ccc(Cl)cc2)o1)c1nc2ccc(-c3ccc(F)cc3)cc2s1 CHEMBL3903461 IC50 6.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)NC4CCC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682451 IC50 6.8 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677610 IC50 6.8 nM
CC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677613 IC50 7.0 nM
CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4458992 IC50 7.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(O)c3F)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682488 IC50 7.1 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc5ccc(F)cc5)sc4c3)cc2)C1 CHEMBL3677627 IC50 7.2 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677599 IC50 7.5 nM
COCC(C)(C)NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cc1 CHEMBL3677576 IC50 7.5 nM
COC1CN(C(=O)c2ccc(-c3ccc4nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc4c3)cc2)C1 CHEMBL3639764 IC50 7.8 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cc(F)cc(Cl)c3)cc2s1 CHEMBL3677539 IC50 8.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(C5=CCOCC5)cc4s3)o2)CC1 CHEMBL3680967 IC50 8.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4cnc(-c5ccccc5)cc4s3)o2)CC1 CHEMBL3680975 IC50 8.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC(F)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682450 IC50 8.2 nM
Cn1nccc1-c1ccc2sc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)nc2c1 CHEMBL3682496 IC50 8.2 nM
COCC(C)(C)NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1 CHEMBL3677577 IC50 8.3 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(-c4ncco4)cc3)cc2s1 CHEMBL3677554 IC50 8.4 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4c(-c5ccccc5)cccc4s3)o2)CC1 CHEMBL3680960 IC50 9.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ccc(F)s5)cc4s3)o2)CC1 CHEMBL3680973 IC50 9.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCC(F)(F)C4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682438 IC50 9.1 nM
NC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677558 IC50 9.2 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(C(F)(F)F)c(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677596 IC50 9.2 nM
COCc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677567 IC50 9.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC[C@@H](O)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682456 IC50 9.5 nM
CC(F)(F)CNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682453 IC50 9.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(S(=O)(=O)NCCO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677566 IC50 9.8 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCOCC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682447 IC50 9.8 nM
COCCNC(=O)c1ccc(-c2cc3sc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)C(C)C)nc3cc2C(F)(F)F)cc1 CHEMBL3677597 IC50 10.0 nM
Cn1ccc(C(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)c(O)c1=O CHEMBL3696224 IC50 10.0 nM
O=C(c1nnc(N[C@H]2CCNC2=O)o1)c1nc2c(F)cc(-c3ccccc3)cc2s1 CHEMBL3964848 IC50 10.0 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccc(C(=O)N5CCOCC5)c(Cl)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4435864 IC50 10.0 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(c4nnc(CNS(N)(=O)=O)o4)S(=O)(=O)Cc4ccccc4)sc3c2)cc1Cl CHEMBL4577903 IC50 10.0 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccc(Cl)c(Cl)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4440746 IC50 10.0 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4cccc(Cl)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4567596 IC50 10.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4520847 IC50 10.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL3677445 IC50 10.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1 CHEMBL3672624 IC50 10.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677638 IC50 10.8 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc5c(c4)CCC(=O)N5)cc3s2)S(C)(=O)=O)o1 CHEMBL3677431 IC50 11.0 nM
Cc1ccc(-c2ccc3nc(Cc4nnc(CC(=O)NC5(C#N)CC5)o4)sc3c2F)s1 CHEMBL3680974 IC50 11.0 nM
O=C(c1nnc(CCc2ncc[nH]2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3920762 IC50 11.0 nM
CC1(Cc2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)NC(=O)N(CC(F)(F)F)C1=O CHEMBL3933562 IC50 11.0 nM
O=C(c1nnc(N(Br)[C@H]2CCNC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3942588 IC50 11.0 nM
O=C(NCc1ccccc1-c1ccc(F)cc1)c1ccn(CC(F)(F)F)c(=O)c1O CHEMBL3696233 IC50 11.06 nM
Cn1c(C(F)(F)F)cc(C(=O)NCc2cccc(-c3ccc(Cl)cc3)c2)c(O)c1=O CHEMBL3696230 IC50 11.27 nM
CC(C)(O)Cn1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(F)cc4)sc3c2)cc1=O CHEMBL3682477 IC50 11.6 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccccc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3672620 IC50 12.0 nM
N#CCNC(=O)Cc1nnc(Cc2nc3c(-c4ccccc4)cccc3s2)o1 CHEMBL3680953 IC50 12.0 nM
CC1(Cc2nnc(C(c3nc4ccc(-c5ccc(C(=O)N6CCOCC6)cc5)cc4s3)S(C)(=O)=O)o2)NC(=O)NC1=O CHEMBL4516251 IC50 12.0 nM
COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)cc1 CHEMBL3677616 IC50 12.1 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cncs3)cc2s1 CHEMBL3677552 IC50 12.3 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCC4CCOCC4)c3)cc2s1 CHEMBL3677642 IC50 13.0 nM
CNc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672613 IC50 13.0 nM
Cc1noc(C)c1-c1ccc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2c1 CHEMBL3672599 IC50 13.0 nM
O=C(c1nnc(CCC2CCN(CC3CC3)CC2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3942057 IC50 13.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4587475 IC50 13.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC[C@H](O)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682458 IC50 13.1 nM
COCCn1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1=O CHEMBL3682480 IC50 13.5 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CCC(F)(F)CC4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682457 IC50 13.5 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cncnc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677484 IC50 13.7 nM
COc1cc2c3c(c1)c(C(F)(F)F)c(CCc1ccccc1)n3CCC2 CHEMBL3092450 IC50 14.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(O)c3F)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682487 IC50 14.0 nM
Cc1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cnc1F CHEMBL3672623 IC50 14.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(C(=O)N5CCOCC5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677428 IC50 14.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(Cc5ccc(F)cc5)cc4s3)o2)CC1 CHEMBL3680966 IC50 14.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ccc(Cl)s5)c(F)c4s3)o2)CC1 CHEMBL3680982 IC50 14.0 nM
CC(C)(C)CN1CCC(c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 CHEMBL3891389 IC50 14.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cccc(C(=O)N4CC(F)(F)C4)c3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3682448 IC50 14.2 nM
CN(C)C(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682454 IC50 14.6 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cncnc3)cc2s1 CHEMBL3677485 IC50 14.7 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CC(F)(F)C4)cc3)cc2s1)S(=O)(=O)Cc1ccc(C(F)(F)F)cc1 CHEMBL3682471 IC50 15.0 nM
Cn1ccc(-c2ccc3nc(Cc4nnc(CC(=O)NC5(C#N)CC5)o4)sc3c2)n1 CHEMBL3680954 IC50 15.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(C(=O)N4CCC4)cc3)cc2s1 CHEMBL4557646 IC50 15.0 nM
CC(C)CN1CC(C(=O)NCCCCc2nc(-c3ccc(Cl)c(Cl)c3)no2)=C(O)C1=O CHEMBL3901201 IC50 15.38 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(C(=O)OC(C)(C)C)cc4)cc3s2)S(C)(=O)=O)s1 CHEMBL3677607 IC50 15.6 nM
Cn1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1=O CHEMBL3682481 IC50 15.8 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cncnc3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677483 IC50 16.0 nM
O=C(c1nnc(CC2NC(=O)N(c3ccccc3)C2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3903208 IC50 16.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3cccc(C(=O)N4CCCCC4)c3)cc2s1 CHEMBL4581408 IC50 16.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CO)cc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677639 IC50 16.1 nM
FC(F)(F)c1c(CCc2ccccc2)n2c3c(cccc13)CCC2 CHEMBL3944727 IC50 17.0 nM
Nc1c(C(=O)N[C@@H]2CCc3cc(OCc4ccccc4)ccc32)[nH]c(=O)[nH]c1=O CHEMBL4513722 IC50 17.0 nM
CC(C)(C)OC(=O)c1ccc(-c2ccc3nc(C(C(=O)N[C@@H]4CCNC4=O)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL3682498 IC50 17.1 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3F)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3682478 IC50 17.2 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL3677609 IC50 17.9 nM
Cn1ccc(C(=O)NCc2cccc(-c3ccccc3)c2)c(O)c1=O CHEMBL3696227 IC50 17.92 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cncnc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677487 IC50 18.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677446 IC50 18.0 nM
CC(C)CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1 CHEMBL3677467 IC50 18.0 nM
CC(C)(C)CN1CC(c2nnc(C(=O)c3nc4c(F)cc(-c5ccccc5)cc4s3)o2)C1 CHEMBL3924178 IC50 18.0 nM
COc1nc(-c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)c(O)c(=O)[nH]1 CHEMBL3900830 IC50 19.0 nM
CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCOC(C)C)C1=O CHEMBL4218352 IC50 19.0 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(CCCN2CCCC2=O)C1 CHEMBL4215063 IC50 19.0 nM
CC(C)(C)CN1CC(c2nnc(Cc3nc4ccc(-c5ccccc5)cc4s3)o2)C1 CHEMBL3948374 IC50 20.0 nM
CN(Cc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1)S(N)(=O)=O CHEMBL3890635 IC50 20.0 nM
CNS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4446812 IC50 20.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccc5c(c4)C(=O)NC5)cc3s2)o1 CHEMBL4575712 IC50 20.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(Cl)c(Cl)c4)sc3c2)cc1 CHEMBL3677618 IC50 20.2 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4cc(Cl)cc(Cl)c4)sc3c2)cc1 CHEMBL3677621 IC50 20.9 nM
CC1(Cc2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)NC(=O)NC1=O CHEMBL3911110 IC50 21.0 nM
Nc1c(C(=O)N[C@H]2CC[C@@H](c3ccc(OCc4ccccc4)cc3)CC2)[nH]c(=O)[nH]c1=O CHEMBL4558644 IC50 21.0 nM
COC(=O)Nc1ccc(-c2ccc3nc(C(c4nnc(CNS(N)(=O)=O)o4)S(=O)(=O)Cc4ccccc4)sc3c2)cc1 CHEMBL4473964 IC50 21.0 nM
CC(C)c1cc(CNC(=O)C(c2nc3ccc(-c4ccccc4)cc3s2)S(C)(=O)=O)on1 CHEMBL3677580 IC50 21.5 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ccc(Cl)cc5)c(F)c4s3)o2)CC1 CHEMBL3680976 IC50 22.0 nM
O=C(c1nnc(N[C@H]2CCOC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3918434 IC50 22.0 nM
CN1CCC(Nc2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)C1=O CHEMBL3911578 IC50 22.0 nM
CN1CC(C(=O)NCCCOc2cccc(Oc3ccccc3)c2)=C(O)C1=O CHEMBL3972790 IC50 22.08 nM
O=C(NCCCCCOc1cc(F)cc(F)c1)SCc1nnc(-c2ccccc2)o1 CHEMBL2381070 IC50 23.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(C(=O)N3CCc4ccccc4C3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677534 IC50 23.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677535 IC50 23.7 nM
COCCNC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3677517 IC50 24.0 nM
COc1ccc(-c2cc3sc(C(C(=O)NCc4nnc(C)o4)S(=O)(=O)Cc4ccccc4)nc3cc2C)cn1 CHEMBL3677443 IC50 24.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CCC(Cc2ccc(F)cc2)C1 CHEMBL3093304 IC50 25.0 nM
NC(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3910703 IC50 25.0 nM
CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCCN2CCCCC2)C1=O CHEMBL4206624 IC50 25.0 nM
O=C(CNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)Cc1ccccc1)NC1CC1 CHEMBL4437751 IC50 25.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CCO)cc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 CHEMBL3677568 IC50 25.7 nM
COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(Br)cc2s1 CHEMBL3677468 IC50 26.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(C(=O)N3CC(F)(F)C3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677533 IC50 26.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)c1[nH]c(=O)[nH]c(=O)c1O CHEMBL4439500 IC50 26.0 nM
CN(CC(F)F)C(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682452 IC50 26.9 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(C(=O)N5CCOCC5)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677442 IC50 27.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ccc(Cl)cn5)cc4s3)o2)CC1 CHEMBL3680972 IC50 27.0 nM
O=C(c1nnc(N[C@H](CCO)C(=O)O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4111172 IC50 27.0 nM
O=C(c1nnc(NC2CCCNC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3943218 IC50 27.0 nM
CN1CC(C(=O)NCc2ccccc2-c2ccccc2)=C(O)C1=O CHEMBL3890157 IC50 27.0 nM
CN1CC(C(=O)NCc2ccc(Oc3ccc(Cl)c(Cl)c3)cc2)=C(O)C1=O CHEMBL3916491 IC50 27.05 nM
CC(=O)Nc1ccc(-c2cccc([C@@H](C)NC(=O)C3=C(O)C(=O)N(c4ccc(F)cc4F)C3)c2)cc1 CHEMBL3956427 IC50 27.08 nM
COCCn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(F)cc4)sc3c2)cn1 CHEMBL3677505 IC50 28.0 nM
Cc1cc2nc(C(C(=O)NCCS(=O)(=O)NS(C)(=O)=O)S(C)(=O)=O)sc2cc1-c1cnn(C)c1 CHEMBL3677472 IC50 28.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5cc6ccccc6s5)cc4s3)o2)CC1 CHEMBL3680969 IC50 28.0 nM
CC(C)C(NC(=O)n1sc2ncccc2c1=O)c1ccc2c(c1)OCCCO2 CHEMBL3686713 IC50 28.0 nM
NC(=O)[C@@H](CCC(F)(F)F)Nc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4111081 IC50 28.0 nM
Cn1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)cc1=O CHEMBL3639813 IC50 28.3 nM
N#CC1(NC(=O)CNC(=O)Cc2nc3ccc(-c4ccccc4)cc3s2)CC1 CHEMBL3699452 IC50 29.0 nM
COc1cc2nc(CC(=O)NCC(=O)NCC#N)sc2cc1-c1ccccc1 CHEMBL3699454 IC50 29.0 nM
Nc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3943750 IC50 29.0 nM
CN1C(=O)C(O)=C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)C1CC(C)(C)C CHEMBL4214459 IC50 29.0 nM
O=C(CNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)CCC(F)(F)F)NC1CC1 CHEMBL4523021 IC50 29.0 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(OC(F)(F)F)cc4)sc3c2)cc1F CHEMBL3677559 IC50 29.2 nM
CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL4207746 IC50 30.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3ccc(-c4ccc(F)nc4)cc3s2)o1 CHEMBL4475891 IC50 30.0 nM
CN1CCN(C(=O)c2ccc(-c3ccc4nc(C(C#N)C(=O)NCC(=O)NC5CC5)sc4c3)cc2)CC1 CHEMBL4438345 IC50 30.0 nM
CN(C)C(=O)c1cccc(-c2ccc3nc(C(C#N)C(=O)NCC(=O)NC4CC4)sc3c2)c1 CHEMBL4557424 IC50 30.0 nM
CC(C)(C)OC(=O)N[C@H]1CC[C@H](c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 CHEMBL3926640 IC50 31.0 nM
Cc1cc(CNC(=O)C(c2nc3ccc(-c4ccccc4)cc3s2)S(C)(=O)=O)on1 CHEMBL3677563 IC50 31.6 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(C(=O)N5CC(F)(F)C5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677585 IC50 32.0 nM
C#CCNC(=O)CNC(=O)Cc1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3699455 IC50 32.0 nM
Cc1ccc(Oc2ccc(CNC(=O)C3=C(O)C(=O)N(C)C3)cc2)c(C)c1 CHEMBL3896224 IC50 32.12 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(N5CCNCC5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677430 IC50 34.0 nM
CS(=O)(=O)C(C(=O)NCCS(=O)(=O)Nc1ccccc1)c1nc2ccc(-c3ccnc(F)c3)cc2s1 CHEMBL3682504 IC50 35.0 nM
O=C(c1nnc(N(Cc2n[nH]c(=O)o2)[C@H]2CCNC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3914254 IC50 35.0 nM
CC(C)S(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cccc(C(=O)N(C)C)c3)cc2s1 CHEMBL3677600 IC50 35.3 nM
N#CCNC(=O)Cc1nnc(Cc2nc3c(Br)cccc3s2)o1 CHEMBL3680952 IC50 36.0 nM
NS(=O)(=O)NCCc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3908566 IC50 36.0 nM
O=C(c1nnc(NCCc2cccnc2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3927746 IC50 36.0 nM
COCCn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC4CC4)sc3c2)cn1 CHEMBL3677507 IC50 37.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(C(=O)NCCc3ccc(F)cc3)ccc2s1 CHEMBL3682503 IC50 37.4 nM
FC(F)(F)c1c(CCc2ccccc2)n2c3c(cccc13)OCC2 CHEMBL3092448 IC50 39.0 nM
COCCNC(=O)c1ccc(-c2cc3sc(C(C(=O)NCc4nnc(C)o4)S(C)(=O)=O)nc3cc2F)cc1 CHEMBL3677594 IC50 39.1 nM
CC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 CHEMBL3672611 IC50 40.0 nM
COc1cc(C(C)NC(=O)n2sc3ncccc3c2=O)cc(CO)c1OC CHEMBL3681997 IC50 40.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(-c4ccc5c(c4)CNC5=O)c(F)cc3s2)o1 CHEMBL4581886 IC50 40.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ccccc5)c(Cl)c4s3)o2)CC1 CHEMBL3680978 IC50 41.0 nM
CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL4207216 IC50 41.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ncccn3)cc2s1 CHEMBL3677624 IC50 41.5 nM
COc1cc(-c2cnn(C)c2)cc2sc(Cc3nnc(CC(=O)NC4(C#N)CC4)o3)nc12 CHEMBL3680981 IC50 42.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(F)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677581 IC50 42.2 nM
FC(F)(F)c1c(CCc2ccccc2)n2c3c(cccc13)CCCC2 CHEMBL3986063 IC50 43.0 nM
CN1CC(C(=O)NCc2ccc(Oc3ccccc3)cc2)=C(O)C1=O CHEMBL3963848 IC50 43.05 nM
CCN1CC(C(=O)N[C@@H]2CCc3cc(-c4ccccc4)ccc32)=C(O)C1=O CHEMBL4114408 IC50 43.54 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677466 IC50 44.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ncc(F)cn5)cc4s3)o2)CC1 CHEMBL3680970 IC50 44.0 nM
CCN1CC(C(=O)NC(C)CCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL4203934 IC50 44.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)C(C)C)sc3c2)cc1 CHEMBL3677595 IC50 44.5 nM
COCCS(=O)(=O)C(C(=O)NCc1cc(C(C)C)no1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677562 IC50 45.9 nM
O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)NC1COC1 CHEMBL3680964 IC50 46.0 nM
O=C(c1nnc(N[C@@H]2CCNC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4110647 IC50 46.0 nM
CS(=O)(=O)C(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4471545 IC50 47.0 nM
O=C(c1nnc(NCCc2ccccc2)o1)c1nc2ccc(-c3ccc(F)cc3)cc2s1 CHEMBL3947398 IC50 49.0 nM
Nc1c(C(=O)N[C@@H]2CCCc3c(OCc4ccccc4)cccc32)[nH]c(=O)[nH]c1=O CHEMBL4583457 IC50 49.0 nM
CN1CC(C(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)=C(O)C1=O CHEMBL3937562 IC50 49.45 nM
C[C@@H](NC(=O)C1=C(O)C(=O)N(C)C1)c1cccc(-c2cccc(C(N)=O)c2)c1 CHEMBL4114049 IC50 49.64 nM
CCN1CC(C(=O)N[C@@H]2CCC(c3ccccc3)c3ccccc32)=C(O)C1=O CHEMBL4109429 IC50 49.99 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(F)c(C(=O)NCC(F)(F)F)cc3s2)o1 CHEMBL4465833 IC50 50.0 nM
Nc1c(C(=O)N[C@@H]2CC[C@H](c3ccccc3)c3ccccc32)[nH]c(=O)[nH]c1=O CHEMBL4586520 IC50 50.0 nM
N#CC(C(=O)NCC(=O)NC1COC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4446981 IC50 50.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL4545633 IC50 50.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(C(=O)N3CC(F)(F)C3)ccc2s1 CHEMBL3682502 IC50 50.3 nM
CC(C)(C)OC(=O)n1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)c1 CHEMBL3677550 IC50 51.4 nM
O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)N1CCOCC1 CHEMBL3680949 IC50 52.0 nM
O=C(Cc1nnc(Cc2nc3ccc(-c4ccc(F)cc4)cc3s2)o1)NC1(CO)CC1 CHEMBL3680959 IC50 52.0 nM
CS(=O)(=O)C(c1nnc(CC2SC(=O)NC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4546575 IC50 53.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)CC1CC1 CHEMBL3677455 IC50 53.8 nM
FC(F)(F)c1c(Cc2ccccc2)n2c3c(cccc13)CCCC2 CHEMBL3939446 IC50 54.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cncnc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677640 IC50 55.6 nM
N#CCNC(=O)CNC(=O)Cc1nc2cc(-c3ccc(OC(F)(F)F)cc3)ccc2s1 CHEMBL3699456 IC50 56.0 nM
O=C(c1nnc(NCCc2ccc(F)cc2)o1)c1nc2ccc(-c3ccc(F)cc3)cc2s1 CHEMBL3925617 IC50 56.0 nM
COCCNC(=O)c1ccc(-c2cc3sc(C(C(=O)NCc4nnc(C)o4)S(=O)(=O)CCOC)nc3cc2F)cc1 CHEMBL3677586 IC50 57.2 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccccc4)cc3s2)S(=O)(=O)CCC(F)(F)F)o1 CHEMBL4589925 IC50 58.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2ccc(-c3ccc(C(=O)N4CC(C)(O)C4)cc3)cc2s1 CHEMBL3677593 IC50 59.0 nM
CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCc2ccncc2)C1=O CHEMBL4212990 IC50 59.0 nM
CN1C(=O)C(O)=C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)C1c1ccccc1Cl CHEMBL4206109 IC50 59.0 nM
CC(C)Cn1c(=O)[nH]c(C(=O)N[C@H]2CC[C@@H](c3ccccc3)CC2)c(O)c1=O CHEMBL4555254 IC50 59.0 nM
Cc1oc(S(=O)(=O)N2CCCCC2)cc1NC(=O)N[C@@H](C)c1ccccc1 CHEMBL467023 IC50 60.0 nM
Cn1ccc(C(=O)NCCCc2ccc(Cl)c(Cl)c2)c(O)c1=O CHEMBL4212095 IC50 61.0 nM
Cn1cc(-c2ccc3nc(Cc4nnc(CC(=O)NC5(C#N)CC5)o4)sc3c2Cl)cn1 CHEMBL3680980 IC50 65.0 nM
C[C@H](NC(=O)OC(C)(C)C)c1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3905059 IC50 66.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N4CC(C)(O)C4)cc3)cc2s1 CHEMBL3677588 IC50 67.0 nM
NS(=O)(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3925422 IC50 68.0 nM
N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ncccn5)cc4s3)o2)CC1 CHEMBL3680971 IC50 69.0 nM
O=C(NCc1ccccc1)n1sc2ncccc2c1=O CHEMBL3681999 IC50 69.0 nM
CN(C)C(=O)c1ccc(-c2ccc3nc(C(C#N)C(=O)NCC(=O)NC4CC4)sc3c2)cc1F CHEMBL4458664 IC50 70.0 nM
Oc1cc2c3c(c1)c(C(F)(F)F)c(CCc1ccccc1)n3CCC2 CHEMBL3971850 IC50 71.0 nM
NC(=O)c1cccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)c1 CHEMBL3682445 IC50 72.5 nM
CS(=O)(=O)NCc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3680945 IC50 73.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 CHEMBL3677620 IC50 74.8 nM
COc1nc(-c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)c(OCc2ccccc2)c(=O)[nH]1 CHEMBL3961752 IC50 76.0 nM
NS(=O)(=O)NCc1nnc(C(c2nc3ccc(-c4ccccc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL4468090 IC50 76.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4cnn(CCN5CCOCC5)c4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677429 IC50 77.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(C(=O)N5CC(C)(O)C5)cc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3677591 IC50 77.0 nM
O=C(Cc1nnc(Cc2nc3c(-c4ccccc4)cccc3s2)o1)NC1(CO)CC1 CHEMBL3680961 IC50 78.0 nM
CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3cnn(CCC(F)(F)F)c3)cc2s1 CHEMBL3677551 IC50 78.1 nM
COc1ccc(CN(Cc2ccc(OC)cc2)S(=O)(=O)CCNC(=O)C(c2nc3ccc(-c4ccccc4)cc3s2)S(C)(=O)=O)cc1 CHEMBL3677465 IC50 80.0 nM
COCCOc1ccc([C@@H](C)NC(=O)n2sc3ncccc3c2=O)cc1OC CHEMBL3686725 IC50 80.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)c1[nH]c(=O)n(CCO)c(=O)c1O CHEMBL4589512 IC50 80.0 nM
FC(F)(F)c1c(CCCOc2ccccc2)n2c3c(cccc13)OCC2 CHEMBL3958164 IC50 82.0 nM
CCN1CC(C(=O)N[C@H]2CC[C@@H](c3ccccc3)CC2)=C(O)C1=O CHEMBL4592858 IC50 82.0 nM
O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)NCCO CHEMBL3680947 IC50 83.0 nM
Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccccc4)cc3s2)S(C)(=O)=O)o1 CHEMBL3639762 IC50 85.0 nM
N#CCCc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3680946 IC50 85.0 nM
CN(C)Cc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1 CHEMBL3686721 IC50 85.0 nM
C[C@@H](NS(N)(=O)=O)c1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL4114591 IC50 86.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCCOCc2ccccc2)C1 CHEMBL3093396 IC50 88.0 nM
NS(=O)(=O)CCNc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3913139 IC50 88.0 nM
CN1C(=O)C(O)=C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)C1C1CC1 CHEMBL4209554 IC50 88.0 nM
Nc1c(C(=O)N[C@H]2CC[C@@H](c3ccccc3)CC2)[nH]c(=O)[nH]c1=O CHEMBL4457722 IC50 91.0 nM
CC(O)CNC(=O)CNC(=O)Cc1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3699453 IC50 92.0 nM
NC(=O)c1ccc(-c2cc3sc(C(C(=O)NC4CCNC4=O)S(=O)(=O)Cc4ccccc4)nc3cc2F)cc1 CHEMBL3672619 IC50 93.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCc4nnc(C)o4)S(=O)(=O)CCOC)sc3c2)cc1 CHEMBL3677592 IC50 93.0 nM
CS(=O)(=O)C(c1nnc(CC2SC(=O)NC2=O)o1)c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1 CHEMBL4563513 IC50 94.0 nM
CS(=O)(=O)NC(=O)CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL4218880 IC50 95.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(Br)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677469 IC50 99.0 nM
COC(=O)N[C@H]1CC[C@H](c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 CHEMBL3920596 IC50 99.0 nM
CCCCCCCCCc1ccc(B(O)O)cc1 CHEMBL485946 IC50 100.0 nM
CN(c1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1)[C@H]1CCNC1=O CHEMBL3914509 IC50 101.0 nM
CC(CC(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1)C(F)(F)F CHEMBL3975269 IC50 101.0 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N4CCCC4)c(F)c3)cc2s1 CHEMBL3677589 IC50 101.4 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N4CCCC4)cc3)cc2s1 CHEMBL3677590 IC50 101.5 nM
NC(=O)CNc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3890383 IC50 104.0 nM
COc1ccc(OC)c(CNC(=O)n2sc3ncccc3c2=O)c1 CHEMBL3682000 IC50 107.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCc2ccccn2)C1 CHEMBL3093392 IC50 110.0 nM
CS(=O)(=O)C(C(=O)NCCS(=O)(=O)c1ccc(F)cc1)c1nc2ccc(-c3ccnc(F)c3)cc2s1 CHEMBL3672618 IC50 110.0 nM
N#CCNC(=O)CNC(=O)Cc1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3699458 IC50 110.0 nM
Cn1cc(-c2ccc3nc(Cc4nnc(CC(=O)NC5(C#N)CC5)o4)sc3n2)cn1 CHEMBL3680979 IC50 110.0 nM
COCCNc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3934474 IC50 110.0 nM
FC(F)(F)c1c(Cc2ccccc2)n2c3c(cccc13)CCC2 CHEMBL3909886 IC50 115.0 nM
CSc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1 CHEMBL3686715 IC50 116.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)c1[nH]c(=O)n(Cc2ccccc2)c(=O)c1O CHEMBL4448686 IC50 117.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCc2ncccc2F)C1 CHEMBL3093394 IC50 120.0 nM
Cc1cccc(C)c1CNC(=O)n1sc2ncccc2c1=O CHEMBL3686712 IC50 120.0 nM
Cn1cc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc4ccc(C(F)(F)F)cc4)sc3c2)ccc1=O CHEMBL3682475 IC50 121.1 nM
COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccc(C(=O)N(C)C)c(F)c3)cc2s1 CHEMBL3677587 IC50 121.3 nM
COc1nc(-c2nnc(C(=O)c3nc4ccc(-c5ccc(F)cc5)cc4s3)o2)c(OCc2ccccc2)c(=O)[nH]1 CHEMBL3895730 IC50 122.0 nM
Cc1oc(S(=O)(=O)N2CCOCC2)cc1NC(=O)Nc1ccccc1 CHEMBL513697 IC50 130.0 nM
Cc1oc(S(=O)(=O)N2CCCCC2)cc1NC(=O)Nc1ccccc1Cl CHEMBL451911 IC50 130.0 nM
COc1ccc(NC(=O)Nc2cc(S(=O)(=O)N3CCCCC3)oc2C)cc1 CHEMBL468071 IC50 130.0 nM
Cc1oc(S(=O)(=O)N2CCCCC2)cc1NC(=O)Nc1ccccc1 CHEMBL513349 IC50 130.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCc2ccc(F)cn2)C1 CHEMBL3093393 IC50 130.0 nM
CC(C)(C)OC(=O)CNc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3950586 IC50 130.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc4c(c3)C(=O)NC4)cc2s1 CHEMBL4553622 IC50 130.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCc2ccc(F)cc2)C1 CHEMBL3093307 IC50 131.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccccc4)c(F)c3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3672621 IC50 131.0 nM
CC(C)NC(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3936371 IC50 135.0 nM
O=C(NCc1ccccc1OC(F)F)n1sc2ncccc2c1=O CHEMBL3686714 IC50 138.0 nM
COC(=O)[C@H](COC(C)(C)C)Nc1nnc(C(=O)c2nc3ccc(-c4ccc(F)cc4)cc3s2)o1 CHEMBL3897986 IC50 140.0 nM
FC(F)(F)c1c(CCCc2ccccc2)n2c3c(cccc13)CCC2 CHEMBL3942244 IC50 143.0 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(F)(F)F)nc3)cc2s1)S(=O)(=O)CCN1CCOCC1 CHEMBL3677641 IC50 145.4 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)cc2s1)S(=O)(=O)Cc1ccc(C(F)(F)F)cc1 CHEMBL3677619 IC50 145.6 nM
NS(=O)(=O)CCNC(=O)C(c1nc2ccc(C(=O)NCCc3c[nH]cn3)cc2s1)S(=O)(=O)CCC(F)(F)F CHEMBL3677531 IC50 148.0 nM
COc1ccc(C(C)NC(=O)n2sc3ncccc3c2=O)cc1OC CHEMBL3682002 IC50 148.0 nM
CC(C)NC(=O)CNc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3933189 IC50 150.0 nM
CC(C)(C)OC(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3966186 IC50 150.0 nM
CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4528020 IC50 150.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCCC2CC2)C1 CHEMBL3093309 IC50 156.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)c1[nH]c(=O)[nH]c(=O)c1NC1CCCC1 CHEMBL4440524 IC50 156.0 nM
NS(=O)(=O)c1cccc(CNC(=O)C(c2nc3ccc(-c4ccncc4Cl)cc3s2)S(=O)(=O)Cc2ccccc2)c1 CHEMBL3677606 IC50 157.8 nM
CC1(O)CN(C(=O)c2ccc(-c3ccc4nc(C(C(N)=O)S(=O)(=O)Cc5ccc(OC(F)(F)F)cc5)sc4c3)cc2)C1 CHEMBL3682476 IC50 157.9 nM
Cc1oc(S(=O)(=O)N2CCCCC2)cc1NC(=O)NC(c1ccccc1)c1ccccc1 CHEMBL466198 IC50 160.0 nM
Cc1ccc(-c2ccc3nc(Cc4nnc(CC(=O)NC5(C#N)CC5)o4)sc3n2)s1 CHEMBL3680977 IC50 160.0 nM
CC1(Cc2nnc(C(c3nc4ccc(-c5ccccc5)cc4s3)S(C)(=O)=O)o2)NC(=O)NC1=O CHEMBL4536805 IC50 160.0 nM
CC(C)c1cc(CNC(=O)c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F)sc3c2)on1 CHEMBL3677532 IC50 166.0 nM
O=C(Nc1ccccc1)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3970136 IC50 168.0 nM
N#CC(C(=O)NCC(=O)NC1CC1)c1nc2ccc(-c3ccc(F)nc3)cc2s1 CHEMBL4459874 IC50 170.0 nM
CS(=O)(=O)C(C(=O)NCc1ccccc1S(N)(=O)=O)c1nc2ccc(-c3ccc(N4CCCCC4)cc3)cc2s1 CHEMBL3677603 IC50 173.3 nM
Nc1c(C(=O)N[C@@H]2CC[C@H](c3ccccc3)C2)[nH]c(=O)[nH]c1=O CHEMBL4476806 IC50 175.0 nM
O=C(c1nnc(NCCc2ccncc2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3950560 IC50 180.0 nM
COc1cccc(CNC(=O)n2sc3ncccc3c2=O)c1 CHEMBL3682003 IC50 182.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](Oc2ccc(F)cc2)C1 CHEMBL3093302 IC50 184.0 nM
FC(F)(F)c1c(CCCc2ccccc2)n2c3c(cccc13)CC2 CHEMBL3947555 IC50 185.0 nM
CS(=O)(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3977383 IC50 186.0 nM
CS(=O)(=O)C(C(=O)NCc1cccc(S(N)(=O)=O)c1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677584 IC50 189.7 nM
N#CCNC(=O)Cc1nnc(Cc2ccc3cc(-c4ccccc4)ccc3n2)o1 CHEMBL3680955 IC50 190.0 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(CCN2CCOCC2)C1 CHEMBL4213958 IC50 190.0 nM
NS(=O)(=O)c1ccccc1CNC(=O)C(c1nc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3677605 IC50 191.2 nM
Cc1oc(S(=O)(=O)N2CCCCC2)cc1NC(=O)Nc1ccc(Cl)cc1 CHEMBL505390 IC50 200.0 nM
CCCCCCCCCCCc1ccc(B(O)O)cc1 CHEMBL1952298 IC50 200.0 nM
CC(NC(=O)n1sc2ncccc2c1=O)c1ccc2c(c1)OCCO2 CHEMBL3681998 IC50 200.0 nM
C[C@H](NS(N)(=O)=O)c1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3896109 IC50 200.0 nM
NS(=O)(=O)NCc1nnc(C(=O)c2nc3cc(-c4ccc(C(=O)NCC(F)(F)F)cc4)c(F)cc3s2)o1 CHEMBL4460376 IC50 200.0 nM
CN1CCN(C(=O)c2ccc(-c3ccc4nc(C(C#N)C(=O)NCC(=O)NC5CCC5)sc4c3)cc2)CC1 CHEMBL4544715 IC50 200.0 nM
COCCS(=O)(=O)NS(=O)(=O)c1cccc(CNC(=O)C(c2nc3cc(-c4ccccc4)ccc3s2)S(=O)(=O)CCOC)c1 CHEMBL3677598 IC50 204.6 nM
COC(=O)CCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3677536 IC50 205.0 nM
Fc1ccc(O[C@H]2CCN(c3ccc(C(F)(F)F)cc3-c3nnn[nH]3)C2)cc1 CHEMBL3093401 IC50 209.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCc2cncc(F)c2)C1 CHEMBL3093395 IC50 214.0 nM
COCCOc1ccc(CNC(=O)n2sc3ncccc3c2=O)cn1 CHEMBL3686717 IC50 216.0 nM
Nc1c(C(=O)N[C@H]2CC[C@@H](c3ccccc3)C2)[nH]c(=O)[nH]c1=O CHEMBL4573343 IC50 218.0 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4cccc(N(C)C)c4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677583 IC50 225.2 nM
O=C(Cc1nc2ccc(-c3ccccc3)cc2s1)NCc1cccc(C(=O)O)c1 CHEMBL3699457 IC50 230.0 nM
CCOc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1OC CHEMBL3686720 IC50 230.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCC2CC2)C1 CHEMBL3093308 IC50 236.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](Oc2ccc(Cl)nc2)C1 CHEMBL3093306 IC50 236.0 nM
COc1ccc(CCNc2nnc(C(=O)c3nc4ccc(-c5ccc(F)cc5)cc4s3)o2)cc1 CHEMBL3897982 IC50 240.0 nM
CC(=O)NCc1ccc(-c2cccc(CNC(=O)C3=C(O)C(=O)N(C)C3)c2)cc1 CHEMBL3980809 IC50 241.3 nM
C[C@@H](NC(=O)C1=C(O)C(=O)N(C)C1)c1cccc(-c2cccc(F)c2)c1 CHEMBL4107624 IC50 245.8 nM
CN1CC(C(=O)NCc2cccc(-c3ccccc3Cl)c2)=C(O)C1=O CHEMBL3967454 IC50 246.3 nM
CN1CC(C(=O)NCc2cccc(-c3ccccc3F)c2)=C(O)C1=O CHEMBL3919680 IC50 249.5 nM
COCCN(C)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1 CHEMBL468281 IC50 250.0 nM
N#CCNC(=O)Cc1nnc(C(F)(F)c2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3680962 IC50 250.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)C1=C(O)C(=O)N(CCCC(F)(F)F)C1 CHEMBL3986807 IC50 252.1 nM
CC(=O)NCc1ccc(-c2cccc([C@@H](C)NC(=O)C3=C(O)C(=O)N(C)C3)c2)cc1 CHEMBL4111510 IC50 253.5 nM
O=C(CC(F)(F)F)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3930374 IC50 255.0 nM
CN1CC(C(=O)NCc2cccc(-c3ccc(CNS(C)(=O)=O)cc3)c2)=C(O)C1=O CHEMBL3910733 IC50 256.6 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@@H](Oc2ccc(F)cc2)C1 CHEMBL3093303 IC50 259.0 nM
O=C(O)CCc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1 CHEMBL3680944 IC50 260.0 nM
CSc1cccc(CNC(=O)n2sc3ncccc3c2=O)c1 CHEMBL3686716 IC50 264.0 nM
CN1CC(C(=O)NCc2ccc(OC3CCOCC3)cc2)=C(O)C1=O CHEMBL3929153 IC50 270.4 nM
C[C@@H](NC(=O)C1=C(O)C(=O)N(C)C1)c1cccc(-c2cccc(C(F)(F)F)c2)c1 CHEMBL4113902 IC50 270.9 nM
C[C@@H](NC(=O)C1=C(O)C(=O)N(C)C1)c1cccc(-c2cccc(C#N)c2)c1 CHEMBL4108138 IC50 277.3 nM
O=C(Cc1nc2ccc(-c3ccccc3)cc2s1)NCc1nc(C(=O)O)cs1 CHEMBL3699451 IC50 280.0 nM
OCCN1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3945916 IC50 280.0 nM
CC(=O)c1cccc(-c2cccc(CNC(=O)C3=C(O)C(=O)N(C)C3)c2)c1 CHEMBL3895192 IC50 285.0 nM
O=C(Cc1nc2cc(-c3cccc(C(F)(F)F)c3)ccc2s1)NCc1cccc(C(=O)O)c1 CHEMBL3699450 IC50 290.0 nM
O=C(c1nnc(NCCc2ccccc2F)o1)c1nc2ccc(-c3ccc(F)cc3)cc2s1 CHEMBL3956627 IC50 290.0 nM
O=C(c1nnc(NC2CC2)o1)c1nc2ccc(-c3ccc(F)cc3)cc2s1 CHEMBL3912491 IC50 290.0 nM
COCCNC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCc4cc(C(C)C)no4)S(C)(=O)=O)sc3c2)cc1 CHEMBL3677561 IC50 290.9 nM
Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(O)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 CHEMBL3677582 IC50 293.6 nM
CN1CC(C(=O)NCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O CHEMBL3894419 IC50 296.0 nM
Cc1oc(S(=O)(=O)N(C)C)cc1NC(=O)Nc1ccccc1 CHEMBL468282 IC50 300.0 nM
COc1ccc(CNc2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)c(OC)c1 CHEMBL3939878 IC50 310.0 nM
O=C(c1nnc(N2CC[C@@H](c3ccccc3)C2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4114488 IC50 310.0 nM
CCCCCCCc1ccc(B(O)O)cc1 CHEMBL1952297 IC50 320.0 nM
Cc1ccc(S(=O)(=O)Nc2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)cc1 CHEMBL3903363 IC50 340.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)c1ccn(CCC(F)(F)F)c(=O)c1O CHEMBL3696231 IC50 352.0 nM
FC(F)(F)c1c(CCCc2ccccc2)n2c3c(cccc13)CCCC2 CHEMBL3917448 IC50 360.0 nM
CC(C)S(=O)(=O)C(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4458141 IC50 360.0 nM
CCCCO[C@H]1CCN(c2ccc(C(F)(F)F)cc2C(=O)O)C1 CHEMBL3093391 IC50 366.0 nM
COCCS(=O)(=O)C(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4473238 IC50 370.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](Oc2ccc(C(F)(F)F)cn2)C1 CHEMBL3093305 IC50 372.0 nM
CN1CC(C(=O)NCCCc2c(Cl)cccc2Cl)=C(O)C1=O CHEMBL3951959 IC50 384.1 nM
N#CCNC(=O)Cc1nnc(Cc2nc3cc(-c4ccccc4)ccc3o2)o1 CHEMBL3680948 IC50 390.0 nM
CC(NC(=O)n1sc2ncccc2c1=O)c1ccc(N2CCOCC2)cc1 CHEMBL3686722 IC50 391.0 nM
O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)N1CC(O)C1 CHEMBL3680963 IC50 400.0 nM
COC(=O)Nc1ccc(-c2ccc3nc(C(=O)c4nnc(CNS(N)(=O)=O)o4)sc3c2)cc1 CHEMBL3905549 IC50 400.0 nM
FC(F)(F)c1c(CCCc2ccccc2)n2c3c(cccc13)OCC2 CHEMBL3911898 IC50 413.0 nM
C[C@H](Nc1nnc(C(=O)c2nc3ccc(-c4ccc(F)cc4)cc3s2)o1)c1ccc(Cl)cc1 CHEMBL3985706 IC50 420.0 nM
CN1C(=O)C(O)=C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)C1C(C)(C)C CHEMBL3964947 IC50 430.2 nM
CN1CC(C(=O)NCCCc2ccccc2C(F)(F)F)=C(O)C1=O CHEMBL3928786 IC50 436.0 nM
CC(=O)OCC(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3954493 IC50 442.0 nM
O=C(c1nnc(N2CC[C@H](c3ccccc3)C2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3965509 IC50 450.0 nM
CS(=O)(=O)C(C(=O)NCCNS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL4461739 IC50 450.0 nM
CCN1CC(C(=O)NCC2CCc3cnc(-c4ccc(Cl)c(Cl)c4)n3C2)=C(O)C1=O CHEMBL3970957 IC50 460.4 nM
CCCCCc1ccc(B(O)O)cc1 CHEMBL1952296 IC50 470.0 nM
Cn1c(Cl)cc(C(=O)NC2CCC(c3ccccc3)CC2)c(O)c1=O CHEMBL3696226 IC50 475.1 nM
CC1C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C(=O)N1CCc1ccc(F)cc1 CHEMBL3972218 IC50 485.7 nM
O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2ccccc2C(=O)O)C1 CHEMBL3908037 IC50 487.7 nM
O=C(c1nnc(N2CC[C@H](OCc3ccccc3)C2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3978971 IC50 490.0 nM
O=C(c1nnc(NC2CCN(CC(F)(F)F)C2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3974633 IC50 490.0 nM
O=C(c1nnc(N2CCN(c3ccc(C(F)(F)F)cc3)CC2)o1)c1nc2ccc(-c3ccccc3)cc2s1 CHEMBL3931564 IC50 494.0 nM
CCOCCO[C@H]1CCN(c2ccc(C(F)(F)F)cc2C(=O)O)C1 CHEMBL3093398 IC50 499.0 nM
COCCN1CCC(CNC(=O)n2sc3ncccc3c2=O)CC1 CHEMBL3686723 IC50 517.0 nM
CN1C(=O)C(O)=C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)C1CCc1ccccc1 CHEMBL3893912 IC50 523.5 nM
COCCOCCO[C@H]1CCN(c2ccc(C(F)(F)F)cc2C(=O)O)C1 CHEMBL3093399 IC50 551.0 nM
CN1CC(C(=O)NCCc2ccc(Cl)cc2)=C(O)C1=O CHEMBL3908882 IC50 559.1 nM
NS(=O)(=O)c1cccc(CNC(=O)Cc2nc3ccc(-c4ccccc4)cc3s2)c1 CHEMBL3699447 IC50 560.0 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCCO)C1 CHEMBL3093397 IC50 570.0 nM
Cc1ccc(CC2C(C(=O)NCCCc3ccc(Cl)c(Cl)c3)=C(O)C(=O)N2C)cc1 CHEMBL3939496 IC50 583.6 nM
O=C(O)c1cc(C(F)(F)F)ccc1N1CC[C@H](OCCN2CCOCC2)C1 CHEMBL3093400 IC50 659.0 nM
O=C(N[C@H]1CC[C@@H](c2ccccc2)CC1)c1ccn(CCCC(F)(F)F)c(=O)c1O CHEMBL3696232 IC50 691.8 nM
FC(F)(F)c1c(CCc2ccccc2)n2c3c(cccc13)CNCC2 CHEMBL3962750 IC50 694.0 nM
CC(c1nnc(CNS(N)(=O)=O)o1)(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)Cc1ccccc1 CHEMBL3982941 IC50 713.0 nM
COc1cc(CNC(=O)n2sc3ncccc3c2=O)cc(OC)c1OC CHEMBL3681996 IC50 926.0 nM
CN(C)CC(=O)N1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 CHEMBL3937026 IC50 959.0 nM
Cc1oc(S(=O)(=O)Nc2ccccc2)cc1NC(=O)Nc1ccccc1 CHEMBL513340 IC50 1000.0 nM
CC1(C)OB(c2ccc(-c3ccccc3)cc2)OC1(C)C CHEMBL1952307 IC50 1000.0 nM
CCCCCCCCCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1 CHEMBL1949700 IC50 1000.0 nM