O=C(N/C(=C\c1ccc(Cl)cc1)C(=O)N1CCOCC1)c1ccc([N+](=O)[O-])cc1 CHEMBL1335274 Potency 0.04467 nM
O=C(Nc1cc(-c2ccc(F)c(F)c2)no1)c1ccccc1F CHEMBL1377941 Potency 0.04467 nM
CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc1ccc(OC)cc1 CHEMBL282121 Potency 0.2 nM
C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)c2csc(N)n2)C(=O)N1S(=O)(=O)O CHEMBL158 Potency 0.3 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1c1cccc2nonc12 CHEMBL400875 Potency 0.4 nM
CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1ccccc1S2 CHEMBL1075 Potency 0.4 nM
O[C@@](CCN1CCCC1)(c1ccccc1)C1CCCCC1 CHEMBL400598 Potency 0.4 nM
C[N+]1([O-])[C@@H]2CC(OC(=O)[C@@H](CO)c3ccccc3)C[C@@H]1[C@H]1O[C@H]12 CHEMBL1492334 Potency 0.4 nM
CCC(C)(C)C(=O)O[C@@H]1C[C@H](C)C=C2C=C[C@H](C)[C@@H](CC[C@H]3C[C@@H](O)CC(=O)O3)[C@H]21 CHEMBL1452881 Potency 0.4 nM
Clc1ccc(CS[C@@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL1446716 Potency 0.4 nM
C[N+]12CCC(CC1)[C@@H](OC(=O)C(O)(c1ccccc1)c1ccccc1)C2 CHEMBL1398637 Potency 0.4 nM
CCCOc1cc(N)ccc1C(=O)OCCN(CC)CC CHEMBL1195 Potency 0.4 nM
Cc1noc(C)c1-c1ccc2ncnc(NCc3ccc(F)c(F)c3)c2c1 CHEMBL1395532 Potency 0.4 nM
O=C(NCc1noc2ccccc12)Nc1ccc(F)cc1F CHEMBL1396765 Potency 0.7 nM
COc1ccc(C2CC(=O)NC(NC(=O)c3ccc(Br)cc3)=N2)c(OC)c1OC CHEMBL1513343 Potency 0.7 nM
O=c1c2ccccc2ncn1-c1ccccc1F CHEMBL1602199 Potency 0.7 nM
C=CCCCCCCCCC(=O)O CHEMBL1276010 Potency 0.8 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCCc1ccccc1 CHEMBL293749 Potency 0.8 nM
O=C(O)C1=CCCNC1 CHEMBL1256362 Potency 0.8 nM
NC(CCCP(=O)(O)O)C(=O)O CHEMBL28862 Potency 0.8 nM
CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@H]5[C@]4(C)[C@H]3CC[C@@]21C CHEMBL1316953 Potency 0.8 nM
O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1 CHEMBL219916 Potency 0.8 nM
Cc1ccc(-c2ncc(Cl)cc2-c2ccc(S(C)(=O)=O)cc2)cn1 CHEMBL416146 Potency 0.8 nM
CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3[C@H](O)[C@@H]12 CHEMBL1607480 Potency 0.8 nM
CNCC[C@H](Oc1ccccc1OC)c1ccccc1 CHEMBL1409777 Potency 0.8 nM
CC(C)C(Br)C(=O)NC(N)=O CHEMBL1515611 Potency 0.8 nM
CC(C)(C)NC[C@H](O)COc1nsnc1N1CCOCC1 CHEMBL499 Potency 0.8 nM
COc1ccc2[nH]cc(CCNC(C)=O)c2c1 CHEMBL45 Potency 0.8 nM
O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1 CHEMBL16 Potency 0.8 nM
COc1ccccc1NC(=O)c1c(C)cc(C)nc1SCC(=O)Nc1ccc(C)cc1 CHEMBL1475551 Potency 0.8 nM
CC(=O)Oc1cc(C)c(OC(C)=O)c2ccccc12 CHEMBL1479848 Potency 0.8 nM
COc1ccccc1CNCCCCCCNCCCCCCCCNCCCCCCNCc1ccccc1OC CHEMBL500996 Potency 0.8 nM
C=C[C@@H]1C[N@@]2CC[C@@H]1C[C@@H]2[C@H](O)c1ccnc2ccc(OC)cc12 CHEMBL1590884 Potency 0.8 nM
CC(C)NC[C@@H](O)COc1cccc2[nH]ccc12 CHEMBL1530633 Potency 0.8 nM
Oc1ccc(Cn2cc[nH]c2=S)cc1 CHEMBL164747 Potency 0.8 nM
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 CHEMBL939 Potency 0.8 nM
Nc1nc(=O)[nH]cc1F CHEMBL1463 Potency 0.8 nM
COc1ccccc1OCC(O)CN1CCN(CC(=O)Nc2c(C)cccc2C)CC1 CHEMBL1404 Potency 0.8 nM
Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)C CHEMBL484928 Potency 0.8 nM
NCC(=O)CCC(=O)O CHEMBL1200582 Potency 0.8 nM
CCCc1nc2c(C)cc(-c3nc4ccccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL1017 Potency 0.8 nM
CCCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 CHEMBL1257076 Potency 0.8 nM
CCOP(=S)(OCC)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 CHEMBL251680 Potency 0.8 nM
NS(=O)(=O)c1cc2c(cc1Cl)NCNS2(=O)=O CHEMBL435 Potency 0.8 nM
COC(=O)[C@@H](N)CS CHEMBL1231844 Potency 0.9 nM
CC(C)CC(CN)CC(=O)O CHEMBL88034 Potency 0.9 nM
O=c1[nH]c(=O)c2nc3ccccc3nc2[nH]1 CHEMBL68500 Potency 0.9 nM
Oc1nc2cc(Cl)ccc2c(O)c1-c1ccc(Oc2ccccc2)cc1 CHEMBL334378 Potency 0.9 nM
CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O CHEMBL302795 Potency 0.9 nM
c1ccc2c(c1)CCCc1cc(NCCN3CCOCC3)nnc1-2 CHEMBL168972 Potency 0.9 nM
C[C@H]1Cc2c(COc3ccccc3)nc3c(c2CO1)CN(C(=O)Nc1cccc(C#N)c1)CC3 CHEMBL1441719 Potency 0.9 nM
CCCc1cc(=O)[nH]c(=S)[nH]1 CHEMBL1518 Potency 0.9 nM
O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3[C@@H]2O[C@H](CO)[C@H](O)[C@H]2O)cc1 CHEMBL1475917 Potency 0.9 nM
COc1ccc2c(c1OC)C(=O)OC2[C@H]1c2cc3c(cc2CCN1C)OCO3 CHEMBL1408680 Potency 0.9 nM
CCCCCCCC(=O)O CHEMBL324846 Potency 0.9 nM
N#CN CHEMBL56279 Potency 0.9 nM
O=C(O)CP(=O)(O)O CHEMBL50300 Potency 0.9 nM
CCCCCCCCCCCCOS(=O)(=O)[O-] CHEMBL23393 Potency 0.9 nM
Nc1nc(Nc2ccccc2)nc2c1ncn2[C@@H]1O[C@H](CO)[C@H](O)[C@H]1O CHEMBL1436882 Potency 0.9 nM
CC(=O)OCC(=O)[C@@]1(OC(C)=O)[C@@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C CHEMBL1200545 Potency 0.9 nM
CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c1ccccc1 CHEMBL40998 Potency 0.9 nM
O=c1onc2n1-c1cc(Br)ccc1OC2 CHEMBL507122 Potency 0.9 nM
NC(=O)NC(=O)Cc1ccccc1 CHEMBL918 Potency 0.9 nM
N=C(NCCC[C@H](N)C(=O)O)N[N+](=O)[O-] CHEMBL227744 Potency 0.9 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL111 Potency 0.9 nM
Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)[C@@H](O)c3ccccc3)[C@@H]2SC1 CHEMBL1552232 Potency 0.9 nM
Nc1nc2c(ncn2COCCO)c(=O)[nH]1 CHEMBL184 Potency 0.9 nM
COC(=O)C(N)CCCNC(=N)N[N+](=O)[O-] CHEMBL1354492 Potency 0.9 nM
Cc1cc2c(cc1Cl)N(C(=O)Nc1cccc3ncccc13)CC2 CHEMBL2110371 Potency 0.9 nM
COC(=O)CCCC1=CC2=CC(=O)C(C)(OC(=O)c3cccs3)C(=O)C2=CN1Cc1ccc2c(c1)OCO2 CHEMBL1364338 Potency 0.9 nM
Cc1ccc(/N=C/N(C)/C=N/c2ccc(C)cc2C)c(C)c1 CHEMBL1365675 Potency 0.9 nM
c1ccc2c(c1)Nc1ccccc1S2 CHEMBL828 Potency 0.9 nM
N=C(N)NC(=O)c1nc(Cl)c(N)nc1N CHEMBL1398126 Potency 0.9 nM
CN1C(=O)CC[C@@H]1c1cccnc1 CHEMBL365343 Potency 0.9 nM
CCNC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1257106 Potency 0.9 nM
CC1CC2C(C(O)CC3(C)C2CCC3(O)C(=O)CO)C2(C)C=CC(=O)C=C12 CHEMBL190259 Potency 0.9 nM
CN(C)c1nc(N)c(C(=O)NC(=N)N)nc1Cl CHEMBL1256020 Potency 0.9 nM
CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1 CHEMBL633 Potency 0.9 nM
CC(=O)Nc1ccc(OC[C@@H](O)CNC(C)C)cc1 CHEMBL1358416 Potency 0.9 nM
CC(N)(C(=O)O)c1ccc(C(=O)O)cc1 CHEMBL299683 Potency 1.0 nM
Cn1c(=O)c2[nH]c(Cl)nc2n(C)c1=O CHEMBL1200406 Potency 1.0 nM
COc1cc2c(CCNC(C)=O)c[nH]c2cc1Cl CHEMBL34730 Potency 1.0 nM
O=C(Nc1ccc2c(c1)OCO2)c1cccn(Cc2ccc(F)cc2)c1=O CHEMBL1354897 Potency 1.0 nM
CCOc1ccc(/C=N/NC2=NCCCCC2)cc1 CHEMBL3208546 Potency 1.0 nM
NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O CHEMBL419213 Potency 1.0 nM
CN1CCCC(n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1 CHEMBL1200809 Potency 1.0 nM
CC1(C)O[C@@H]2C[C@H]3[C@H]4C[C@H](F)C5=CC(=O)C=C[C@@]5(C)[C@@H]4[C@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 CHEMBL1525482 Potency 1.0 nM
COC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL453066 Potency 1.0 nM
COC(=O)C1=C(C(=O)OC)[C@@H]2N(C)c3ccc(OC)cc3[C@@]23C[C@@H](C(=O)OC)N(C(=O)COCc2ccccc2)C3=N1 CHEMBL1414201 Potency 1.0 nM
CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C=O)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1 CHEMBL90555 Potency 1.1 nM
COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 CHEMBL511 Potency 1.1 nM
Cc1cccc(C)c1NC1=NCCCS1 CHEMBL1256022 Potency 1.1 nM
CC1(C)CCC(NC(=O)[C@@H](N)CCC(=O)O)CC1 CHEMBL1255840 Potency 1.1 nM
Cc1ccc2nc3sc(C(=O)Nc4ccc(F)cc4)cc3cc2c1 CHEMBL1559809 Potency 1.1 nM
CCCCCCCC1=Cc2ccc(F)cc2C(C(C(=O)OC)C(=O)OC)N1C(=O)OC CHEMBL1609179 Potency 1.3 nM
NC(=O)c1cccc(N)c1 CHEMBL81977 Potency 1.3 nM
CCOc1ccc(-c2cc(CCCC(=O)NCc3cccnc3)no2)cc1 CHEMBL1477366 Potency 1.3 nM
COc1cc(CC(C)N)c(OC)cc1I CHEMBL1255748 Potency 1.4 nM
ClC(Cl)(Cl)Cl CHEMBL44814 Potency 1.4 nM
CC[N@+]1(C)CCC[C@@H](OC(=O)C(O)(c2ccccc2)c2ccccc2)C1 CHEMBL1393947 Potency 1.4 nM
COc1cc(/C=C2/NC(=O)N(CC(=O)Nc3ccc(C)cc3)C2=O)ccc1Oc1ccc([N+](=O)[O-])cn1 CHEMBL1309943 Potency 1.4 nM
COc1cc(C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2)cc(OC)c1OC CHEMBL1603820 Potency 1.6 nM
CO[C@H]1C[C@@H](O[C@@H]2[C@H](C)[C@H](O[C@@H]3O[C@@H](C)C[C@@H](N(C)C)[C@@H]3O)[C@H](C)C[C@]3(CO3)C(=O)[C@H](C)[C@H](O)[C@H](C)[C@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@H]1O CHEMBL1357195 Potency 1.6 nM
CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1 CHEMBL343633 Potency 1.6 nM
COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1 CHEMBL1428 Potency 1.8 nM
CN(C)[C@H]1C(O)=C(C(N)=O)C(=O)[C@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3C[C@@H]12 CHEMBL1512321 Potency 1.8 nM
CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@H]21 CHEMBL1336122 Potency 1.8 nM
NC(=O)C[S+]([O-])C(c1ccccc1)c1ccccc1 CHEMBL1373 Potency 1.8 nM
CC(=O)O[C@H]1C(=O)[C@@]2(C)[C@H]([C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C1C3(C)C)[C@]1(OC(C)=O)CO[C@@H]1C[C@@H]2O CHEMBL428647 Potency 1.8 nM
CCOc1ccc2nc3cc(N)ccc3c(N)c2c1 CHEMBL94007 Potency 1.8 nM
COc1cc2nc(N(C)CCCNC(=O)[C@@H]3CCCO3)nc(N)c2cc1OC CHEMBL1317208 Potency 1.8 nM
C[C@H]1CC[C@]2(OC1)O[C@@H]1C[C@@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@@H]4CC(=O)[C@@]3(C)[C@H]1[C@@H]2C CHEMBL1401685 Potency 1.8 nM
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 CHEMBL62193 Potency 1.8 nM
O=C(Nc1cccc(C2=NCCN2)c1)Nc1cccc(C2=NCCN2)c1 CHEMBL1362780 Potency 1.8 nM
O=C(O)c1cc(O)c2ccc(Cl)cc2n1 CHEMBL311389 Potency 1.8 nM
CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC CHEMBL1555736 Potency 2.0 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 Potency 2.0 nM
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C3C(C[C@H](O)C21C)C1(C)CC[C@@H](O)CC1C[C@H]3O CHEMBL1594626 Potency 2.0 nM
C[C@H]1Cc2c(COc3ccccc3)nc3c(c2CO1)CN(S(=O)(=O)c1ccc2c(c1)OCCN2C)CC3 CHEMBL1526957 Potency 2.0 nM
CN(C(=O)CSC1=NC2C(N=N1)c1cc(Br)ccc1N2C)C1CCCCC1 CHEMBL1438136 Potency 2.0 nM
COc1ccc(CCN(C)C(=O)/C=C/c2c(Cl)nc3ccccn23)cc1OC CHEMBL1425133 Potency 2.0 nM
Cc1c(Br)c(C(F)(F)F)nn1CC(=O)NCCCn1ccnc1 CHEMBL1427364 Potency 2.0 nM
CN1CCC(=C2c3ccccc3CC(=O)c3sccc32)CC1 CHEMBL534 Potency 2.0 nM
N[C@H](C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL280563 Potency 2.0 nM
CCN[C@@H]1CN(CCCOC)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 CHEMBL51533 Potency 2.0 nM
O=C1C2C=CC=CC2=NC(=S)N1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1372997 Potency 2.0 nM
COc1ccc([C@@H]2CNC(=O)C2)cc1OC1CCCC1 CHEMBL430893 Potency 2.0 nM
COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1 CHEMBL637 Potency 2.0 nM
Cn1ccnc1S CHEMBL1515 Potency 2.0 nM
CCCCCC[C@H]1C(=O)O[C@H](C)[C@H](NC(=O)c2cccc(NC=O)c2O)C(=O)O[C@@H](C)[C@H]1OC(=O)CC(C)C CHEMBL1433958 Potency 2.2 nM
CC1CCC(NC(=O)c2ccc(/C=C3\Oc4ccccc4N(C)C3=O)cc2)CC1 CHEMBL1604854 Potency 2.2 nM
NCC(CP(=O)(O)O)c1ccc(Cl)cc1 CHEMBL1255941 Potency 2.2 nM
Cc1ccnc(NC(=O)c2ccc(Cl)c(NC(=O)C(C)Oc3ccccc3)c2)c1 CHEMBL1304751 Potency 2.2 nM
COc1ccc(N2CCN(C(=O)c3noc4c3CCCCC4)CC2)cc1 CHEMBL1513353 Potency 2.2 nM
CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 CHEMBL121 Potency 2.2 nM
Cc1ccc(C(=O)C(=S)N2CCOCC2)cc1 CHEMBL1573172 Potency 2.2 nM
CCNc1nc(Cl)nc(NCC)n1 CHEMBL1605837 Potency 2.2 nM
CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]1[C@H]3C[C@H](F)C4=CC(=O)C=C[C@@]4(C)[C@]3(F)[C@H](O)C[C@@]12C CHEMBL1597239 Potency 2.2 nM
CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)C4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 CHEMBL1434334 Potency 2.2 nM
O=C1CC[C@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@@H]1O5 CHEMBL1592773 Potency 2.2 nM
O=C(CN1C(=O)C2CC=CCC2C1=O)Nc1ccc(-c2nnc3n2CCCCC3)cc1 CHEMBL1502255 Potency 2.2 nM
Cc1cccc(C#Cc2ccccc2)n1 CHEMBL1255868 Potency 2.2 nM
CC(C)NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL2062275 Potency 2.2 nM
CCN1CCC[C@H]1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC CHEMBL267044 Potency 2.2 nM
CC12CC3CC(C)(C1)CC(N)(C3)C2 CHEMBL1699 Potency 2.2 nM
C#CCN1C(C)=C(C(=O)OC)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCC)=C1C CHEMBL1256776 Potency 2.2 nM
COc1c(O)cc2c(c1O)[C@@H]1O[C@@H](CO)[C@@H](O)[C@@H](O)[C@@H]1OC2=O CHEMBL1356881 Potency 2.5 nM
c1ccc(CN(CC2=NCCN2)c2ccccc2)cc1 CHEMBL1305 Potency 2.5 nM
CCCCCCCCCCCCCCCCCCO CHEMBL24640 Potency 2.5 nM
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO CHEMBL1766 Potency 2.5 nM
O=C1C(O)=C(O)O[C@@H]1[C@@H](O)CO CHEMBL40274 Potency 2.5 nM
CCCCCCOc1ccccc1C(N)=O CHEMBL1405973 Potency 2.5 nM
COC(=O)CC1c2ccccc2C=C(/C=C/c2ccc3c(c2)OCO3)N1C(=O)OC CHEMBL1358292 Potency 2.5 nM
Cc1nn(C)c2c1c(-c1ccccc1)cc(=O)n2C(C)C(=O)NCc1ccc(F)cc1 CHEMBL1438623 Potency 2.8 nM
CSc1nsc(SC)c1C(=O)Nc1ccc(Cl)cc1 CHEMBL1300473 Potency 2.8 nM
COC(=O)C(c1ccccc1)C1CCCCN1 CHEMBL1722 Potency 2.8 nM
N=C(N)N/N=C/c1c(Cl)cccc1Cl CHEMBL1200560 Potency 2.8 nM
CSc1nc2nc(-c3cccc(C(F)(F)F)c3)ccn2n1 CHEMBL1329416 Potency 2.8 nM
Oc1[nH]ncc1/C=N/c1ccc(Cl)cc1Cl CHEMBL3209174 Potency 2.8 nM
Fc1ccc(-c2nn(-c3ccc(Cl)cc3)c3c2cnc2ccc(F)cc23)cc1 CHEMBL1456061 Potency 2.8 nM
COc1ccc(Cl)cc1N=C(S)Nc1ccccc1F CHEMBL1387872 Potency 2.8 nM
CCCCOc1ccc(CSCCN=C(N)N)cc1 CHEMBL1417241 Potency 2.8 nM
COc1ccccc1CN1CCN(Cc2nc(Cc3ccccc3)no2)CC1 CHEMBL1483558 Potency 2.8 nM
COc1ccc(C(=O)n2c(C)c(CCO)c(=O)n2C)cc1 CHEMBL1382395 Potency 2.8 nM
Cc1ccc(C)c(N2CCN(C(=O)CCc3c(C)nn(-c4ccc(N5CCCC5)nn4)c3C)CC2)c1 CHEMBL1355189 Potency 2.8 nM
Cc1ccc(S(=O)(=O)Nc2ccc(-c3ccc(N4CCCCCC4)nn3)cc2)cc1C CHEMBL1479844 Potency 2.8 nM
COc1ccccc1-n1cnnc1SCC(=O)Nc1cccnc1Cl CHEMBL1480865 Potency 2.8 nM
O=C(CSc1nnc(NC2CCCCC2)s1)Nc1ccc2c(c1)C(=O)c1ccccc1C2=O CHEMBL1480989 Potency 2.8 nM
COc1ccc2cc([C@H](C)C(=O)[O-])ccc2c1 CHEMBL1200806 Potency 2.8 nM
CSc1nnc(-c2ccccc2SC)o1 CHEMBL1353167 Potency 2.8 nM
CCN(CC)S(=O)(=O)c1nnc(NC(=O)COc2cccc(C)c2)s1 CHEMBL1516323 Potency 2.8 nM
Cc1c(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)sc2nc3n(c(=O)c12)CCCC3 CHEMBL1354675 Potency 2.8 nM
CCc1cc(O)nc(SCCCF)n1 CHEMBL1350962 Potency 2.8 nM
CCN(C(=O)Cn1cc(C(=O)c2ccc(F)cc2)c(=O)c2ccc(C)nc21)c1cccc(C)c1 CHEMBL1472659 Potency 2.8 nM
COc1cc2c(cc1OC)C1=C(C#N)CC/C(=N\C(=O)c3ccco3)N1CC2 CHEMBL3191848 Potency 2.8 nM
CCc1ccccc1NC(=O)CN(c1ccccc1)S(=O)(=O)c1ccsc1C(=O)OC CHEMBL1398232 Potency 2.8 nM
O=C1CN(/N=C\c2ccc([N+](=O)[O-])o2)C(=O)N1 CHEMBL1515795 Potency 2.8 nM
CCOc1ccc(NC(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)cc1 CHEMBL1356090 Potency 2.8 nM
Cc1c(Cl)cccc1NC(=O)c1oc2ccc(S(=O)(=O)N3CCCCCC3)cc2c1C CHEMBL1475161 Potency 3.2 nM
Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cc(F)ccc1F CHEMBL1448706 Potency 3.2 nM
O=C1C(=CNN2CCOCC2)C(=O)N(c2ccccc2)C(=S)N1c1ccccc1 CHEMBL1527432 Potency 3.2 nM
O=C(Nc1cccc([N+](=O)[O-])c1)C(=O)N1CCCCC1 CHEMBL1477767 Potency 3.2 nM
Cc1cc(C)nc(N/N=C/c2ccc(N3CCOCC3)cc2)n1 CHEMBL3190474 Potency 3.2 nM
Cc1nc2ccc(S(=O)(=O)N(CC(=O)Nc3cccc(Cl)c3)Cc3ccccc3)cc2s1 CHEMBL1394497 Potency 3.2 nM
Cc1nc2ccccc2c(=O)n1Nc1cccc(Cl)c1 CHEMBL1449051 Potency 3.2 nM
CCCCCCCC1=Cc2ccccc2C(C(C(=O)OC)C(=O)OC)N1C(=O)OC CHEMBL1514468 Potency 3.2 nM
CC1CN(Cc2csc(-c3ccc(Cl)cc3)n2)CC(C)O1 CHEMBL1359861 Potency 3.2 nM
CC(c1ccccc1F)n1cc(C(=O)NCCCc2nc3ccccc3[nH]2)nn1 CHEMBL1488697 Potency 3.2 nM
COC(=O)CSc1nc2ccc(N)cc2s1 CHEMBL1330814 Potency 3.2 nM
CCN1CCN(S(=O)(=O)c2ccc(Oc3ccccc3OC)cc2)CC1 CHEMBL1410438 Potency 3.2 nM
CCN(CC)C(=O)N[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL1528238 Potency 3.2 nM
CCc1nn2c(=O)cc(COC(=O)c3ccco3)nc2s1 CHEMBL1473203 Potency 3.2 nM
O=C(NC1CC(=O)N(c2cccc(F)c2)C1)c1ccc(Br)o1 CHEMBL1354866 Potency 3.2 nM
Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C/c3ccccc3)CC2)cc1 CHEMBL30008 Potency 3.2 nM
C=C(C)CNC(=S)N/N=C/c1ccc(NC(C)=O)cc1 CHEMBL3193999 Potency 3.2 nM
NC(=O)c1c(N=C(S)Nc2ccccc2)sc2c1CCCC2 CHEMBL1300975 Potency 3.2 nM
CCCCOC(=O)c1ccc(Nc2nnc(-n3nc(C)cc3C)c3ccccc23)cc1 CHEMBL1478721 Potency 3.2 nM
CCCCCc1nnc(NC(=O)c2ccc(=O)n(C)n2)s1 CHEMBL1567332 Potency 3.2 nM
O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1 CHEMBL23588 Potency 3.2 nM
Cc1cc2oc(=O)cc(CSc3nnc(C)n3N)c2cc1C(C)C CHEMBL1450588 Potency 3.2 nM
Cc1cccc(C(=O)NC(=O)Nc2c(C)cc(C)nc2C)c1 CHEMBL1577844 Potency 3.2 nM
CC(C)(C)C(=O)Nc1cccc(OC(F)(F)C(F)Cl)c1 CHEMBL1329086 Potency 3.2 nM
COc1cccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3[nH]c(-c4ccccc4)nc3c2)c1 CHEMBL1568175 Potency 3.2 nM
COc1ccc(NC(S)=Nc2ncccc2C)cc1OC CHEMBL1487485 Potency 3.2 nM
CCOC(=O)N1CCN(C(=O)c2ccc(OC)c(S(=O)(=O)N3CCOCC3)c2)CC1 CHEMBL1578018 Potency 3.2 nM
Cc1ccc(Cl)cc1NC(=O)CCCN1C(=O)CCn2nc(-c3cn(C)c4ccccc34)cc21 CHEMBL1512347 Potency 3.2 nM
CC1(C)S[C@@H]2[C@@H](/N=C/N3CCCCCC3)C(=O)N2[C@H]1C(=O)O CHEMBL1590255 Potency 3.2 nM
CCOc1ccccc1CNC(=O)CCc1c(C)nn(-c2ccc(N3CCCC3)nn2)c1C CHEMBL1551523 Potency 3.2 nM
Cc1ncc(COC(=O)C(C)C)c2cc(C(=O)Nc3ccccc3C(F)(F)F)c(=O)oc12 CHEMBL1398749 Potency 3.2 nM
Cc1cccc(NC(=S)N(CCN2CCOCC2)Cc2ccccc2F)c1 CHEMBL1497465 Potency 3.2 nM
COc1cc(C(=O)NNC(=O)c2cc(C)[nH]n2)cc(OC)c1OC CHEMBL1575540 Potency 3.2 nM
COc1ccc(C(=O)NCC(c2cccnc2)N2CCc3ccccc3C2)cc1 CHEMBL1553433 Potency 3.2 nM
CC1CC(C)(C)N=C(S)N1CCCC(=O)Nc1ccccc1F CHEMBL1555856 Potency 3.2 nM
CC(=O)NCCc1nc2cc(NC(=O)c3cccs3)ccc2n1C CHEMBL1359235 Potency 3.2 nM
COC(=O)c1ccc2c(=O)n(CCCCCC(=O)N3CCN(c4cccc(C)c4C)CC3)c(=O)[nH]c2c1 CHEMBL1448303 Potency 3.2 nM
CC12CCC(C/C1=N/OC(=O)c1cccc([N+](=O)[O-])c1)C2(C)C CHEMBL3192215 Potency 3.2 nM
COc1ccc(C(=O)NNC(=O)CCCCC(=O)NNC(=O)c2ccc(OC)cc2)cc1 CHEMBL1452346 Potency 3.2 nM
COc1cc(C(=O)O)cc(NC(=O)c2cccs2)c1OC CHEMBL1401932 Potency 3.2 nM
COc1cc(OC)c(NC(=O)c2ccc3c(SCC(=O)O)c4c(nc3c2)CCCC4)cc1Cl CHEMBL1374733 Potency 3.2 nM
CC(C)(C)c1ccc(O)cc1 CHEMBL16217 Potency 3.2 nM
Cc1ccc(-c2nc3ncccc3o2)cc1NC(=O)c1cccs1 CHEMBL1344091 Potency 3.2 nM
CCOc1c(Cl)cc(CNC(C)C(O)c2ccccc2)cc1OC CHEMBL1597653 Potency 3.2 nM
Cc1cc(C)cc(N(C(=O)CCC(=O)Nc2ccccn2)C(C(=O)NC(C)C)c2ccc(O)cc2)c1 CHEMBL1502616 Potency 3.2 nM
O=C(c1ccccc1Sc1ccc([N+](=O)[O-])cc1Cl)N1CCOCC1 CHEMBL1560032 Potency 3.2 nM
COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc1cccc(C(C)=O)c1 CHEMBL1305791 Potency 3.2 nM
O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 CHEMBL1542663 Potency 3.2 nM
Cc1ccc(OCCSc2nnc(-c3cccs3)o2)cc1Cl CHEMBL1521049 Potency 3.2 nM
Cc1ccc(-n2nc(C(=O)Nc3ccc(F)cc3Cl)c(=O)n(C)c2=O)cc1 CHEMBL1554341 Potency 3.2 nM
CCCCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)N3CCCC3)c2=O)CC1 CHEMBL1434822 Potency 3.2 nM
CCOC(=O)C1(CCCc2ccccc2)CCN(C(=O)C2CCCO2)CC1 CHEMBL1542818 Potency 3.2 nM
CCn1cc(CN2CCN(Cc3ccsc3)C(CCO)C2)cn1 CHEMBL1560233 Potency 3.2 nM
O=C(CSc1nccn1C1CCCC1)Nc1ccccc1 CHEMBL1442755 Potency 3.2 nM
CCOC(=O)c1sc(NC(=O)c2nc3ncccn3n2)c(C(=O)OC(C)C)c1C CHEMBL1554405 Potency 3.2 nM
CCOC(=O)c1ccccc1NC(=O)N1CCOc2ccc(Cl)cc21 CHEMBL1552331 Potency 3.2 nM
Cn1nc(C(=O)NCc2ccco2)c2ccccc2c1=O CHEMBL1306320 Potency 3.2 nM
COc1cccc(CC2(CO)CCCN(Cc3nc(-c4cccs4)oc3C)C2)c1 CHEMBL1533486 Potency 3.2 nM
CCOC(=O)CSCCOc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1OC CHEMBL1306457 Potency 3.2 nM
COc1ccc(C2C(C(=O)N3CCN(C)CC3)c3cc(OC)c(OC)cc3C(=O)N2C)cc1 CHEMBL1403894 Potency 3.2 nM
O=C(Cn1cc([N+](=O)[O-])cn1)NCc1ccco1 CHEMBL1572739 Potency 3.2 nM
Fc1ccc(-c2noc3ncnc(NCC4CCN(Cc5ccc(Cl)cc5)CC4)c23)cc1 CHEMBL1403908 Potency 3.2 nM
C/C(=N\OC(=O)c1c(-c2ccccc2Cl)noc1C)c1ccncc1 CHEMBL3195307 Potency 3.2 nM
CC1CCN(S(=O)(=O)c2ccc(C(=O)Nc3nnc(-c4ccncc4)o3)cc2)CC1 CHEMBL1347628 Potency 3.2 nM
CCOC(=O)c1cnn(-c2ccccc2)c1-n1cccc1C(=O)C(=O)N(C)C CHEMBL1583241 Potency 3.2 nM
Cc1c(Cl)cccc1NC(=O)C1CCN(S(C)(=O)=O)CC1 CHEMBL1411748 Potency 3.2 nM
CC(C)CCNC(=O)NC(=O)COC(=O)CNC(=O)C1CCCCC1 CHEMBL1387687 Potency 3.2 nM
CC(C)c1ccccc1OCCCCCNCCO CHEMBL1534049 Potency 3.2 nM
O=C(O)CC(NC(=O)Cc1ccccc1)c1cc([N+](=O)[O-])ccc1Cl CHEMBL1534792 Potency 3.2 nM
CCOc1ccc(C(NC(C)=O)c2ccc(OC)c(OC)c2)cc1 CHEMBL1495536 Potency 3.2 nM
Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 CHEMBL1591352 Potency 3.2 nM
C/C(=N\Nc1cc(N2CCOCC2)nc(C)n1)c1cccc([N+](=O)[O-])c1 CHEMBL3198447 Potency 3.2 nM
C=CCN(c1ccc(OC)cc1)S(=O)(=O)c1ccc(Cl)c(C(=O)OCC(=O)NC2CC2)c1 CHEMBL1416297 Potency 3.2 nM
Cc1ccc(N2CC(=O)C(c3ccccc3)=C2N)cc1 CHEMBL1307225 Potency 3.2 nM
CCCS(=O)(=O)N1CCCC(C(=O)NCCCOC)C1 CHEMBL1411522 Potency 3.2 nM
COc1cc(NC(=O)Cn2ncc3c([nH]c4ccc(C)cc43)c2=O)cc(OC)c1OC CHEMBL1455864 Potency 3.2 nM
COc1ccc(CCNCC(O)Cn2ccc3ccccc32)cc1OC CHEMBL1331971 Potency 3.2 nM
Cc1cc(/C=C2\C(=O)NC(=O)N(Cc3ccccc3Cl)C2=O)c(C)n1-c1ccc(C(=O)O)cc1 CHEMBL1583598 Potency 3.2 nM
O=C(Nc1nccs1)c1ccc(COc2ccccc2Cl)o1 CHEMBL1443328 Potency 3.2 nM
CCOC(=O)CSc1nc2cccnc2n1C CHEMBL1534003 Potency 3.2 nM
O=C(NCCN1CCCCC1)c1c(O)nc2ccccc2c1O CHEMBL1416518 Potency 3.2 nM
COC(=O)CSc1nnc(CNC(=O)c2cc(OC)cc(OC)c2)n1-c1ccc(F)cc1 CHEMBL1416803 Potency 3.2 nM
N=C(N)SCCN CHEMBL1256182 Potency 3.2 nM
CCOc1ccc(N2C(=O)CC(NCCNc3ccc(C(=O)c4cccs4)cc3)C2=O)cc1 CHEMBL1426772 Potency 3.2 nM
CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CCOC)/c1=N/C(=O)c1c(-c2c(F)cccc2Cl)noc1C CHEMBL3197839 Potency 3.2 nM
C=C1c2cccc(O)c2C(=O)C2=C(O)[C@@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12 CHEMBL1560884 Potency 3.2 nM
COc1ccccc1CNc1ccc2nnc(CCNC(=O)c3ccc(C)cc3)n2n1 CHEMBL1573016 Potency 3.2 nM
N#C/C(=C\c1c[nH]nc1-c1ccccc1Br)C(=O)O CHEMBL1417311 Potency 3.2 nM
Cc1ccc(S(=O)(=O)Nc2ccc(N(C)C)cc2)cc1 CHEMBL1416554 Potency 3.2 nM
O=C(O)/C=C/C(=O)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1426570 Potency 3.2 nM
Nc1cc(O)nc(SCC(=O)NNC(=O)Cc2ccccc2)n1 CHEMBL1534086 Potency 3.2 nM
CC(=O)N(C(C)=O)N1C(=O)/C(=C/c2ccc(Cl)cc2)SC1=S CHEMBL1583264 Potency 3.2 nM
O=C(CCNC(=O)c1ccc([N+](=O)[O-])cc1)N/N=C/c1ccc(F)cc1 CHEMBL3198429 Potency 3.2 nM
C/C(=N\NC(=O)CNc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 CHEMBL3193239 Potency 3.2 nM
COc1ccc(OC)c(NC(=O)NNC(=O)CCCOc2ccc(Cl)cc2C)c1 CHEMBL1568795 Potency 3.2 nM
CC1(C)Cc2nc3sc4c(N(CCO)CCO)nnnc4c3cc2CO1 CHEMBL1422674 Potency 3.2 nM
CCC1C(=O)NCCN1Cc1nc(-c2ccc(C)s2)oc1C CHEMBL1519226 Potency 3.2 nM
CC(C)(C)OC(=O)N1CCC(c2c(C(=O)N3CCN(c4ncccn4)CC3)cnn2-c2ccc(F)cc2F)CC1 CHEMBL1315045 Potency 3.2 nM
O=C(O)c1cccc2c1C(=O)c1ccccc1-2 CHEMBL1373884 Potency 3.2 nM
COc1ccc(CNS(=O)(=O)c2cc3c(cc2C)N(C)CCO3)cc1 CHEMBL1410059 Potency 3.2 nM
NS(=O)(=O)c1ccc(NC(=O)COC(=O)CCc2ccccc2)cc1 CHEMBL1441247 Potency 3.2 nM
COC(=O)c1sc2cccc(F)c2c1S(=O)(=O)N1CCN(c2ccc(C)cc2C)CC1 CHEMBL1481148 Potency 3.2 nM
CC1(C)CC(=O)C(/C=N/CC2CCN(C(=O)Cc3ccccc3)CC2)=C(O)C1 CHEMBL1993220 Potency 3.2 nM
O=C(Nc1cccc(S(=O)(=O)N2CCCC2)c1)c1cc(-c2ccccn2)nc2ccccc12 CHEMBL1481187 Potency 3.2 nM
C[C@H]1CS(=O)(=O)CCN1/N=C\c1ccc([N+](=O)[O-])o1 CHEMBL1436217 Potency 3.2 nM
Cc1cccc(N(C)S(=O)(=O)c2c(C(=O)N3CCCCCC3)c(C)n(C)c2C)c1 CHEMBL1396972 Potency 3.2 nM
O=C(CCCSc1nc(O)c2ccccc2n1)c1ccccc1 CHEMBL1558540 Potency 3.2 nM
O=C(CCC(=O)N1CC2CCCN2c2ccccc21)NCc1ccc(Cl)cc1 CHEMBL1334868 Potency 3.2 nM
O=C(CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1)NCc1cccs1 CHEMBL1532060 Potency 3.2 nM
Cc1nn(-c2ccc(N3CCCC3)nn2)c(C)c1CCC(=O)N1CCN(c2ccccc2F)CC1 CHEMBL1317309 Potency 3.2 nM
CN1Cc2c(N)cccc2C(c2ccccc2)C1 CHEMBL1256842 Potency 3.2 nM
Cc1cc(=O)n(Cc2cccc(Cl)c2)c2c1c(C)nn2C CHEMBL1332982 Potency 3.2 nM
COc1cccc(NC(=O)CSC(N)=O)c1 CHEMBL1578344 Potency 3.2 nM
CCOC(=O)N1CCC(NC(=O)c2cnn(-c3ccccc3)c2C2CCN(C(=O)OC(C)(C)C)CC2)CC1 CHEMBL1597114 Potency 3.2 nM
O=C1COc2cc(S(=O)(=O)CCC(=O)N3CCN(c4ccccc4)CC3)c(Cl)cc2N1 CHEMBL1436319 Potency 3.2 nM
O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2nc(C3CC3)sc2n1 CHEMBL1513043 Potency 3.2 nM
CCOC(=O)c1c(S(=O)(=O)N2CCCC(C(=O)Nc3ncccc3C)C2)c(C)n(C)c1C CHEMBL1410780 Potency 3.2 nM
CCOC(=O)CSc1nc2ccc(NC(=O)c3ccc(Cl)cc3)cc2s1 CHEMBL1315180 Potency 3.2 nM
Cc1ccc(S(=O)(=O)NCCC(c2ccccc2)c2ccccc2)cc1C(=O)O CHEMBL1344429 Potency 3.2 nM
Oc1c(C(c2ccccc2)N2CCC3(CC2)OCCO3)sc2nc(-c3ccco3)nn12 CHEMBL1518816 Potency 3.2 nM
O=C(NCCc1csc(-c2ccccc2)n1)c1c(F)cccc1F CHEMBL1451756 Potency 3.2 nM
Cc1ccc(OCC(=O)n2nc(C)cc2C)c(C)c1 CHEMBL1492181 Potency 3.2 nM
COc1cc([C@H]2c3cc4c(cc3[C@@H](O)[C@@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1OC CHEMBL1330659 Potency 3.2 nM
COc1ccc(N2CCN(S(=O)(=O)CCNC(=O)Cc3ccc(OC)c(OC)c3)CC2)cc1 CHEMBL1515071 Potency 3.2 nM
Cc1nn(CCCC(=O)Nc2cccnc2Cl)c(C)c1[N+](=O)[O-] CHEMBL1567452 Potency 3.2 nM
NC(=O)CSc1nc(C2CC2)nc2sc3c(c12)CCCC3 CHEMBL1342883 Potency 3.2 nM
COc1ccccc1NC(=O)Cn1cc(C(=O)c2ccncc2)c(=O)c2cc(C)ccc21 CHEMBL1553901 Potency 3.2 nM
Cc1cc(N(CCO)CCO)ccc1N=Nc1cc(F)ccc1F CHEMBL1303599 Potency 3.2 nM
Cc1cc(C)cc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)c(C)cc32)c1 CHEMBL1609114 Potency 3.2 nM
COc1ccc(C(=O)C2CCCN(S(=O)(=O)c3cccnc3)C2)c(C)c1 CHEMBL1597824 Potency 3.2 nM
COc1ccc(N2CCN(C(CNS(=O)(=O)c3ccc(OC)c(C)c3)c3ccco3)CC2)cc1 CHEMBL1441653 Potency 3.2 nM
COc1cccc(NC(=O)CSc2nc(=O)[nH]c3c2CCCC3)c1 CHEMBL1590878 Potency 3.2 nM
OCCC1CN(Cc2cnn(-c3ccc(F)cc3)c2)CCN1Cc1ccsc1 CHEMBL1362639 Potency 3.2 nM
CC1CCCC(C)N1C(=O)CSc1nc(O)c2ccccc2n1 CHEMBL1580363 Potency 3.2 nM
CCNc1ccc(P(=O)(c2ccccc2)c2ccccc2)cc1 CHEMBL1503237 Potency 3.2 nM
CCc1ccc(-n2nc(C)c3c(C(=O)Nc4cc(OC)cc(OC)c4)cc(C)nc32)cc1 CHEMBL1335887 Potency 3.2 nM
COc1ccc2nc(N(Cc3cccnc3)C(=O)CCc3ccccc3)sc2c1 CHEMBL605499 Potency 3.2 nM
COC(=O)c1ccc2c(c1)NC(=O)CS2 CHEMBL1541443 Potency 3.2 nM
CCn1c(SCc2ccccc2)nnc1-c1nonc1NC(C)=O CHEMBL1591582 Potency 3.2 nM
Cc1ccc(C)c(N2C(=O)N(Cc3c(F)cccc3Cl)c3ccccc3S2(=O)=O)c1 CHEMBL1378432 Potency 3.2 nM
Cc1ccc(C(=O)NC(=S)Nc2ccc(N3CCOCC3)cc2)c(C)c1 CHEMBL1333542 Potency 3.2 nM
Cc1ccc(CNC(=O)c2ccc(CS(=O)(=O)Cc3ccc(C)cc3)o2)cc1 CHEMBL1570367 Potency 3.2 nM
Cc1cc(C)n(CC(=O)c2ccccc2)c(=O)c1C#N CHEMBL1549478 Potency 3.2 nM
Cc1ccc(NC(=O)CSc2nnc(-c3ccco3)o2)c(C)c1 CHEMBL1312682 Potency 3.2 nM
Cc1ccc(OCC(=O)NCC2(N3CCOCC3)CCCCC2)cc1C CHEMBL1314410 Potency 3.2 nM
CCO[C@H]1O[C@@H]([C@H](COCc2ccccc2)OCc2ccccc2)[C@@H](OCc2ccccc2)[C@H]1O CHEMBL1446743 Potency 3.2 nM
O=C(O)/C=C/c1ccc2noc(-c3ccccc3)c2c1 CHEMBL1368139 Potency 3.2 nM
CC1=Nc2cc(=O)[nH]c(=S)n2C(c2cccc([N+](=O)[O-])c2)/C1=C(\O)OC(C)C CHEMBL1995383 Potency 3.2 nM
Cc1cccc(NC(=O)c2cc3c(=O)n4ccccc4nc3n(CC(C)C)c2=N)c1 CHEMBL1312992 Potency 3.2 nM
CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 CHEMBL1313100 Potency 3.2 nM
Cc1ccccc1-n1nnnc1SC1CCOC1=O CHEMBL1511027 Potency 3.2 nM
CC(C)(C)n1nnnc1SCC(=O)Nc1nn(-c2ccccc2)nc1C(N)=O CHEMBL1432769 Potency 3.2 nM
CCN1CCN(CCCNC(=O)c2ccc3nc(Cc4ccc(OC)cc4)oc3c2)CC1 CHEMBL1555285 Potency 3.2 nM
COc1cccc(NC(S)=NNC(=O)CCn2cc([N+](=O)[O-])cn2)c1 CHEMBL1353483 Potency 3.2 nM
Cn1c(C(O)C(O)c2ccccc2)nc2ccccc21 CHEMBL1353755 Potency 3.2 nM
Cc1cc2c(cc1S(=O)(=O)CCC(=O)NCc1ccccc1)OCC(=O)N2 CHEMBL1365915 Potency 3.2 nM
O=C(CSc1ccc(-c2ccc(Br)cc2)nn1)N1CCOCC1 CHEMBL1589447 Potency 3.2 nM
O=C(OCCOc1ccc(Br)cc1)c1ccc(Cl)nc1 CHEMBL1393639 Potency 3.2 nM
O=C(Nc1ccc2c(c1)nc1n2CCSC1)c1ccco1 CHEMBL1313979 Potency 3.2 nM
CCOC(=O)Cn1c(=O)n(CC2CCCO2)c2nc(-c3ccccc3Cl)nc(C(N)=O)c21 CHEMBL1394351 Potency 3.2 nM
Cc1ccc(S(=O)(=O)N2CCOC2CNC(=O)C(=O)NCCc2c[nH]c3ccccc23)cc1 CHEMBL1447757 Potency 3.2 nM
Cc1cc(Br)cc(C)c1NC(=O)c1sc2ncn(Cc3cccc(F)c3)c(=O)c2c1C CHEMBL1358878 Potency 3.2 nM
CCOc1ccc(Cl)cc1CNCCCSc1nnnn1C CHEMBL1365493 Potency 3.2 nM
COc1ccc(/N=C2\SC(C(=O)Nc3ccc(F)cc3)CC(=O)N2C)cc1 CHEMBL3191738 Potency 3.2 nM
Cc1cc2c(cc(C(=O)OC(C(=O)NCC3CCCO3)C(C)C)n2C)o1 CHEMBL1546582 Potency 3.2 nM
CCn1c(CN2CCOCC2)nc2cc(NC(=O)c3cc(OC)c(OC)c(OC)c3)ccc21 CHEMBL1601586 Potency 3.2 nM
O=C1CCC(=O)N1c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1349842 Potency 3.2 nM
C=CCNC(S)=NNC(=O)c1cc(O)ccc1O CHEMBL1507662 Potency 3.2 nM
CC(Oc1ccccc1)C(=O)OCc1cc(=O)n2nc(C(C)C)sc2n1 CHEMBL1554967 Potency 3.2 nM
Nc1nc2ccccc2n1C(=O)c1ccc(F)cc1 CHEMBL1535050 Potency 3.2 nM
CCN(C(=O)CSc1nc2n[nH]c(C)c2c(=N)n1-c1cccc(OC)c1)c1cccc(C)c1 CHEMBL1365690 Potency 3.2 nM
CCN(CC)CCN=C(S)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 CHEMBL1545935 Potency 3.2 nM
O=C(COc1ccccc1)NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1 CHEMBL1395913 Potency 3.2 nM
COc1ccc2c(c1)CCc1c(C(=O)N(C)c3ccccc3)noc1-2 CHEMBL1326191 Potency 3.2 nM
COc1ccc(NC(=O)COC(=O)C23CC4CC(CC(Cl)(C4)C2)C3)c(OC)c1 CHEMBL1545072 Potency 3.2 nM
O=C(CN1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1)c1ccc(Cl)cc1 CHEMBL1545412 Potency 3.2 nM
O=C(O)CCC(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 CHEMBL1484857 Potency 3.2 nM
Cc1nc2ccccc2c2nc(NC(=O)C(F)(F)F)nn12 CHEMBL1390076 Potency 3.2 nM
COc1cccc(N2CC(NC(=O)c3ccco3)CC2=O)c1 CHEMBL1474488 Potency 3.2 nM
CCC(OC(C)=O)c1cc2c(cc1[N+](=O)[O-])OCCO2 CHEMBL1602378 Potency 3.2 nM
OCCN(CCO)c1ncnc2c1cnn2-c1ccc(F)cc1 CHEMBL1435485 Potency 3.2 nM
Cc1cc2nc(C)c(Cl)c(O)n2n1 CHEMBL1483590 Potency 3.2 nM
CCOC(=O)c1ccccc1NC(=O)CSc1nc(=O)[nH]c2c1CCC2 CHEMBL1356070 Potency 3.2 nM
CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1cc(OC)ccc1-2 CHEMBL52030 Potency 3.2 nM
Cc1oncc1C(=O)Nc1ccc(C(F)(F)F)cc1 CHEMBL960 Potency 3.2 nM
CNC(C)(C)Cc1ccccc1 CHEMBL1201234 Potency 3.2 nM
O=C(NCc1ccco1)C1CCN(C(=O)N2CCOc3ccccc32)CC1 CHEMBL1356072 Potency 3.2 nM
COc1ccc(S(=O)(=O)n2[nH]c(=O)c(CCO)c2C)c([N+](=O)[O-])c1 CHEMBL1418338 Potency 3.2 nM
CCC(C)NC(=O)c1ccc2nc(CCc3ccccc3)oc2c1 CHEMBL1318242 Potency 3.2 nM
COc1cc(/C=C/C(=O)OCC(=O)NCc2cccs2)ccc1OCC#N CHEMBL1390168 Potency 3.2 nM
CCOc1ccc2nc(N3CCN(C(=O)c4ccco4)CC3)sc2c1 CHEMBL1356335 Potency 3.2 nM
O=C(COC(=O)c1ccncc1)c1ccc(Br)cc1 CHEMBL1523048 Potency 3.2 nM
COc1ccc(C(=O)C2CCCN(C(=O)CCC3=NNC(=O)CC3)C2)c(C)c1 CHEMBL1309481 Potency 3.2 nM
CCOc1cccc(CNCc2cccnc2)c1OCc1ccccc1 CHEMBL1366005 Potency 3.2 nM
Cc1ccc(S(=O)(=O)NC(=O)Nc2cc(C)on2)cc1 CHEMBL1496728 Potency 3.2 nM
Cc1ccc(/C=C/C(=O)OCC(=O)Nc2ccccc2Sc2ccccc2)cc1 CHEMBL1457302 Potency 3.2 nM
CCOc1cc(C(=O)OCC(=O)NC(C)c2ccccc2)ccc1OCC(=O)N1CCOCC1 CHEMBL1327105 Potency 3.2 nM
O=C(COc1ccc(F)cc1)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1 CHEMBL1445818 Potency 3.2 nM
CC(=O)Nc1ccccc1C(=O)OCc1ccccc1F CHEMBL1413145 Potency 3.2 nM
CCC(C)NC(=O)Cc1ccc(NC(=O)N2CCCCc3ccccc32)cc1 CHEMBL1472746 Potency 3.2 nM
CCOC(=O)c1ccc(S(=O)(=O)Nc2cc(C(=O)O)ccc2Cl)cc1 CHEMBL1506621 Potency 3.2 nM
O=C(C1CC1)N1CCN(c2nc3ccc(F)cc3s2)CC1 CHEMBL1318070 Potency 3.2 nM
COc1cc(C(=O)N2C(=O)c3cccc(N)c3C2=O)cc(OC)c1OC CHEMBL1467237 Potency 3.2 nM
CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)C(C)OC(=O)c1cccc(S(=O)(=O)N(C)C)c1 CHEMBL1310624 Potency 3.2 nM
CCN(CC(=O)Nc1ccc(N2CCOCC2)cc1)C(=O)COc1ccc2c(C)cc(=O)oc2c1 CHEMBL1350661 Potency 3.2 nM
CCOc1ccccc1CNC(=O)CCc1cn(C)c2ccccc12 CHEMBL1602282 Potency 3.2 nM
CCC(C)(C)NC(=O)C1CCN(S(=O)(=O)c2c(C)noc2/C=C/c2ccc(C)cc2)CC1 CHEMBL1433445 Potency 3.2 nM
CCc1ccccc1N=C(S)N(Cc1cccc(C)c1)c1cccnc1 CHEMBL1430117 Potency 3.2 nM
O=C(N/N=C/c1ccccn1)c1c[nH]c2ccccc12 CHEMBL3195676 Potency 3.5 nM
O=S(=O)(Nc1ccc(-c2ccc(N3CCCC3)nn2)cc1)c1cccc(C(F)(F)F)c1 CHEMBL1435913 Potency 3.5 nM
CCOc1ccc(-c2cc(C(=O)NC(C)c3ccccc3)c3ccccc3n2)cc1 CHEMBL1594614 Potency 3.5 nM
NC1=C(c2nc3ccccc3s2)C(=O)CN1NC(=O)c1c[nH]c2ccccc12 CHEMBL1340216 Potency 3.5 nM
Cc1cc(=O)n(Cc2cccc(Cl)c2)c2c1c(C)nn2-c1ccccc1 CHEMBL1399364 Potency 3.5 nM
CCOC(=O)C1=C[C@@]2(CC)CCCN3CCc4c(n1c1ccccc41)[C@H]32 CHEMBL1360725 Potency 3.5 nM
Nc1c(-c2ccccc2)c(CSc2nc3ccccc3[nH]2)nn1-c1cccc(C(=O)O)c1 CHEMBL1399396 Potency 3.5 nM
Cc1ccc(C(=O)CSc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 CHEMBL1595087 Potency 3.5 nM
COc1ccc(CCN(Cc2nc(O)c3ccccc3n2)C(=O)C2CC2)cc1 CHEMBL1370461 Potency 3.5 nM
Cc1ccc(-c2cc(C(F)(F)F)n3ncc(C(=O)N4CCCCC4c4cccnc4)c3n2)cc1 CHEMBL1576547 Potency 3.5 nM
C[C@H]1Cc2c(COc3ccccc3)nc3c(c2CO1)CN(C(=O)Cc1cccs1)CC3 CHEMBL1473201 Potency 3.5 nM
COCC1CCN(Cc2cn(C)nc2-c2cccc(Cl)c2)C1 CHEMBL1576623 Potency 3.5 nM
NC(=Nc1ccccc1)Nc1nc(O)cc(CSc2nnnn2-c2ccccc2)n1 CHEMBL1300918 Potency 3.5 nM
O=C(Nc1cccc2ccccc12)OCc1cncs1 CHEMBL1331773 Potency 3.5 nM
C=CCN(C(=O)c1csnn1)C(C(=O)NC(C)(C)C)c1ccncc1 CHEMBL1420973 Potency 3.5 nM
Cc1cccc(C)c1N=C(S)NCCSc1ccc(Cl)cc1 CHEMBL1381941 Potency 3.5 nM
CCOC(=O)c1ccccc1NC(=O)C=C(C)C CHEMBL1459419 Potency 3.5 nM
C=C1C(C(=O)Nc2ccc(OCC)cc2)C1C(=O)Nc1ccc(OCC)cc1 CHEMBL1498892 Potency 3.5 nM
CNCCc1c[nH]c2ccc(O)cc12 CHEMBL1256286 Potency 3.5 nM
O=C(NCCS(=O)(=O)N1CCN(c2ccccc2F)CC1)c1cc(=O)c2ccccc2o1 CHEMBL1448075 Potency 3.5 nM
CN(C)S(=O)(=O)c1ccc2oc(SCC(=O)Nc3ccccc3F)nc2c1 CHEMBL1302199 Potency 3.5 nM
COc1ccc(-c2cc(C3CCN(Cc4cccc(C(F)(F)F)c4)CC3)[nH]n2)cc1 CHEMBL1381257 Potency 3.5 nM
COc1ccccc1N1CCN(c2ccc(Cl)nn2)CC1 CHEMBL1398753 Potency 3.5 nM
CSCc1cc(N2CCOCC2)nc(-c2ccccc2)n1 CHEMBL1299619 Potency 3.5 nM
Cc1cc(C)c(C#N)c(SC[S+]([O-])c2ccc(C(C)(C)C)cc2)n1 CHEMBL1369631 Potency 3.5 nM
Clc1ncc(CN2CCN(c3ccccc3)CC2)s1 CHEMBL1487540 Potency 3.5 nM
O=C(CN(C(=O)c1ccccc1Cl)N1C(=O)C2C3C=CC(C3)C2C1=O)c1cccs1 CHEMBL1480454 Potency 3.5 nM
Nc1ccc(C23CC4CC(CC(C4)C2)C3)cc1 CHEMBL1414270 Potency 3.5 nM
CCOC(=O)C1(Cc2ccc(OC)cc2)CCN(C(=O)c2ccc3[nH]ccc3c2)CC1 CHEMBL1453687 Potency 3.5 nM
CCN1CCCc2cc(CN(CCN3CCOCC3)C(S)=Nc3ccccc3C)ccc21 CHEMBL1481195 Potency 3.5 nM
COC(=O)c1ccc(Oc2ccc(C(F)(F)F)cn2)cc1 CHEMBL1520920 Potency 3.5 nM
COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1 CHEMBL268869 Potency 3.5 nM
O=C(/C=C/c1ccc([N+](=O)[O-])cc1)NCCN1C(=O)S/C(=C\c2ccc(F)cc2)C1=O CHEMBL1385923 Potency 3.5 nM
Cc1nc(CSc2ccc(Cl)cc2)cc(N2CC(C)OC(C)C2)n1 CHEMBL1560468 Potency 3.5 nM
COc1ccccc1/C=N/N1C(=O)C(CC(=O)Nc2ccc([N+](=O)[O-])cc2OC)S/C1=N\c1cccc(C)c1C CHEMBL3212654 Potency 3.5 nM
Cc1nn(C(=O)Cn2cc([N+](=O)[O-])cn2)c(C)c1Cl CHEMBL1306216 Potency 3.5 nM
COC(=O)c1sccc1S(=O)(=O)N(CC(=O)NCc1ccccc1)c1ccc(C)c(C)c1 CHEMBL1317708 Potency 3.5 nM
COc1ccc(N2C(=O)CSC23C(=O)N(Cc2cccc(C(F)(F)F)c2)c2ccccc23)cc1 CHEMBL1357622 Potency 3.5 nM
CCOc1ccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)cc1 CHEMBL1533861 Potency 3.5 nM
Cn1c(=O)c2c(nc(CN3CCN(C(=O)c4ccco4)CC3)n2Cc2cccc(Cl)c2)n(C)c1=O CHEMBL1582164 Potency 3.5 nM
O=C(/C=C/c1cnc2ccccc2c1)NNc1ccc(F)cc1 CHEMBL1347108 Potency 3.5 nM
Cc1cc(C)nc(NC(=O)c2ccc(Cl)cc2Cl)n1 CHEMBL1404785 Potency 3.5 nM
COc1cc2cc(C(=O)O)[nH]c2c(OC)c1OC CHEMBL1346897 Potency 3.5 nM
O=C(NCc1ccc2c(c1)CCN2C(=O)c1ccc(F)cc1)c1ccc(Br)o1 CHEMBL1554504 Potency 3.5 nM
CCCCn1cnc2cc(C)c(C)cc21 CHEMBL1411641 Potency 3.5 nM
CCOC(=O)C1(Cc2ccccc2Cl)CCN(C(=O)CCn2ccnc2C)CC1 CHEMBL1417295 Potency 3.5 nM
O=C(/C=C/c1ccc([N+](=O)[O-])cc1)NNC(=O)C1CC1 CHEMBL1534621 Potency 3.5 nM
Cc1ccc(N2CCN(C(=O)c3nn(C)c4c3CS(=O)(=O)c3ccccc3-4)CC2)c(C)c1 CHEMBL1318770 Potency 3.5 nM
Cc1cc(N(CCO)CCO)nc(-n2nc(C)cc2C)n1 CHEMBL1530205 Potency 3.5 nM
O=c1c(-c2ccccc2)nc2cnc(N3CCOCC3)nc2n1Cc1ccc(F)cc1 CHEMBL1333061 Potency 3.5 nM
Cc1cc(C(F)(F)F)nc(SCCN2CCOCC2)c1C#N CHEMBL1332854 Potency 3.5 nM
CN(C)C(=N)NC(=N)N CHEMBL1431 Potency 3.5 nM
CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 CHEMBL1256754 Potency 3.5 nM
CCSc1ccccc1C(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL1382516 Potency 3.5 nM
CCOc1ccc(Br)cc1S(=O)(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1 CHEMBL1481167 Potency 3.5 nM
Cc1nn(CC2CC2)c(=O)n1-c1ccccc1 CHEMBL1321360 Potency 3.5 nM
CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)Nc1cccc(C(F)(F)F)c1)n2CC CHEMBL1374931 Potency 3.5 nM
C=CCN1C(=O)NC(=O)C(CCc2ccncc2)(CCc2ccncc2)C1=O CHEMBL1579907 Potency 3.5 nM
CCn1nc(C)c2c(-c3ccccc3)cc(=O)n(C(C)C(=O)NCCC(C)C)c21 CHEMBL1414664 Potency 3.5 nM
O=C1NCC2(CCN(CCc3ccccc3)CC2)O1 CHEMBL576127 Potency 3.5 nM
CCOC(=O)Cc1csc(NC(=O)c2ccc(Br)s2)n1 CHEMBL1382615 Potency 3.5 nM
O=C1CC(c2c[nH]c3ccccc23)C(=O)N1 CHEMBL1374439 Potency 3.5 nM
O=C(NNC(=O)c1ccncc1)Nc1cccc([N+](=O)[O-])c1 CHEMBL1596806 Potency 3.5 nM
O=C(c1ccc(F)cc1)[C@@H]1[C@@H](C(=O)c2ccccc2)[C@@]2(C(=O)Nc3ccccc32)[C@H]2c3ccccc3C=CN12 CHEMBL1558204 Potency 3.5 nM
CCN(C(=O)CSc1nnc(Cc2cccc3ccccc23)n1N)C1CCS(=O)(=O)C1 CHEMBL1502500 Potency 3.5 nM
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 CHEMBL471 Potency 3.5 nM
O=C(C(=O)N1CCOCC1)c1c[nH]c2ccccc12 CHEMBL438352 Potency 3.5 nM
CCOC(=O)c1ccc(NC(=O)c2noc3c2CCCC3)cc1 CHEMBL1571900 Potency 3.5 nM
Cc1ccc(-c2cc(-c3nnc(S)o3)c3ccccc3n2)cc1 CHEMBL1469202 Potency 3.5 nM
CC(C)Cn1c(S)nnc1-c1ccc(Br)o1 CHEMBL1547657 Potency 3.5 nM
COC(=O)c1cc(NC(=O)c2cccc(F)c2)cc(C(=O)OC)c1 CHEMBL1470684 Potency 3.5 nM
CCCCn1c(=O)c(C(=O)OCC)c(O)c2ccccc21 CHEMBL1588163 Potency 3.5 nM
COC(=O)c1cc2ccsc2n1Cc1ccccc1F CHEMBL1367973 Potency 3.5 nM
O=Cc1ccc(-c2ccc(F)cc2)o1 CHEMBL1549489 Potency 3.5 nM
CC1=CCC(C(C)(C)O)CC1 CHEMBL449810 Potency 3.5 nM
O=C(NCCc1csc(-c2cccc(F)c2)n1)c1ccc(Br)o1 CHEMBL1328455 Potency 3.5 nM
CCOc1ccc(C(=O)CCN2CCCCC2)cc1 CHEMBL1471745 Potency 3.5 nM
O=C(c1ccc(F)cc1)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 CHEMBL2062337 Potency 3.5 nM
Cc1ccc(C)c(N2CCN(C(=O)CN3C(=O)CSc4c3c(C)nn4-c3ccccc3)CC2)c1 CHEMBL1377803 Potency 3.5 nM
COc1ccccc1NC(=O)CCCn1c(=S)[nH]c2ccccc2c1=O CHEMBL1586758 Potency 3.5 nM
COC(=O)c1sc(NC(=S)NC(=O)c2ccccc2C)nc1C CHEMBL1484249 Potency 3.5 nM
Cc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 CHEMBL1429497 Potency 3.5 nM
Cc1nnc(SC(C)C(=O)Nc2nccs2)s1 CHEMBL1429366 Potency 3.5 nM
CC(C)Oc1cccc(C(=O)C2CCCN(Cc3cnc(N4CCOCC4)s3)C2)c1 CHEMBL1563955 Potency 3.5 nM
O=C(N/N=C/c1ccc(OCc2cnc(Cl)s2)cc1)c1ccncc1 CHEMBL3189192 Potency 3.5 nM
CC1=CC(C)C2(CO)COC(c3ccc(O)cc3)C1C2C CHEMBL1451012 Potency 3.5 nM
COc1ccc(C(=O)Nc2cccnc2)cc1S(=O)(=O)N1CCOCC1 CHEMBL1569221 Potency 3.5 nM
COc1ccc(F)cc1C(=O)C1CCCN(Cc2ccc(Oc3ncccn3)cc2)C1 CHEMBL1585946 Potency 3.5 nM
C[N+](C)(C)CCCCCC[N+](C)(C)C CHEMBL1405927 Potency 3.5 nM
CNCCCCOc1ccccc1Cc1ccccc1 CHEMBL543763 Potency 3.5 nM
CCOc1ccc2c(c1)c(C(C)=O)c(C)n2Cc1ccco1 CHEMBL1605378 Potency 4.0 nM
OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)nc(N3CCCCC3)c2n1 CHEMBL932 Potency 4.0 nM
Sc1nnc(-c2cccnc2)n1/N=C/C=C/c1ccco1 CHEMBL3190112 Potency 4.0 nM
CCOC(=O)O[C@@H](C)OC(=O)[C@@H]1N2C(=O)[C@@H](NC(=O)[C@@H](N)c3ccccc3)[C@H]2SC1(C)C CHEMBL1595709 Potency 4.0 nM
CC1Cc2ccccc2N1CC(=O)NC(=O)NC1CCCCC1 CHEMBL1538081 Potency 4.0 nM
Cc1ccc(-n2c(SCc3ccccc3C)nc3[nH]ncc3c2=O)cc1C CHEMBL1434827 Potency 4.0 nM
O=C(CCCn1c(=O)[nH]c2ccsc2c1=O)Nc1ccc(F)cc1 CHEMBL1610662 Potency 4.0 nM
CC(=O)N1CCc2cc(CNC(=O)Cc3ccc(F)cc3)ccc21 CHEMBL1476023 Potency 4.0 nM
CCOc1cc(C2C3=C(O)CCCC3=Nc3ccc4ncccc4c32)ccc1O CHEMBL1364369 Potency 4.0 nM
CNC(=O)Oc1ccc2c(c1)[C@]1(C)CCN(C)[C@@H]1N2C CHEMBL94 Potency 4.0 nM
CCN(CC)CCNC(=O)c1ccc(N)cc1 CHEMBL605 Potency 4.0 nM
O=C(Cc1ccccc1)c1c[nH]c(C(=O)NCc2ccncc2)c1 CHEMBL1533947 Potency 4.0 nM
CC1CCN(CCCNC(=O)c2cc(Sc3ccc(F)cc3)nc3ccccc23)CC1 CHEMBL1521843 Potency 4.0 nM
C=CCNC(=O)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cc2[N+](=O)[O-])CC1 CHEMBL1505184 Potency 4.0 nM
CC(=O)Nc1c(I)c(C(=O)N[C@H]2[C@@H](O)[C@H](O)[C@H](CO)O[C@@H]2O)c(I)c(N(C)C(C)=O)c1I CHEMBL1522397 Potency 4.0 nM
O=C1/C(=C/c2nc3ccccc3[nH]2)SC(=S)N1C1CCCCC1 CHEMBL1347019 Potency 4.0 nM
CCc1nc2ccccc2n1CC1CC1(Cl)Cl CHEMBL1604769 Potency 4.0 nM
CC(C)=CCC/C(C)=C/CC/C(C)=C/CSc1ccccc1C(=O)O CHEMBL23293 Potency 4.0 nM
COc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)c(OC)c1 CHEMBL1453488 Potency 4.0 nM
CCc1c(C(=O)OC)[nH]cc2nc3cc(OC)c(OC)cc3c1-2 CHEMBL17468 Potency 4.0 nM
COCC(=O)Nc1c(I)c(C(=O)NC[C@@H](O)CO)c(I)c(C(=O)N(C)C[C@@H](O)CO)c1I CHEMBL1397069 Potency 4.0 nM
CN(C)CCNC(=O)CN1N=C(c2ccccc2)CCC1=O CHEMBL1610273 Potency 4.0 nM
NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1 CHEMBL1643 Potency 4.0 nM
CN(NC(=O)c1ccccc1)c1ncc(C(F)(F)F)cc1Cl CHEMBL1479600 Potency 4.0 nM
NCCO/C=C/[C@H](N)C(=O)O CHEMBL1412824 Potency 4.0 nM
N#C/C(=C\c1ccc2c(c1)OCO2)C(=O)NCc1ccco1 CHEMBL1608854 Potency 4.0 nM
CC(=O)Nc1ccc2nc(SCC(=O)O)sc2c1 CHEMBL1597675 Potency 4.0 nM
CC(=O)c1ccccc1NC(=O)CN1C(=O)CS/C1=C\c1nc(-c2ccc(C)cc2)cs1 CHEMBL1375040 Potency 4.0 nM
Cc1cc(C(=O)OCC(=O)NCCC(C)C)c2ccccc2n1 CHEMBL1403023 Potency 4.0 nM
Cc1ccc(N(CC(=O)NCc2ccc(OC(C)C)cc2)S(=O)(=O)N(C)C)cc1 CHEMBL1475558 Potency 4.0 nM
Cc1nnc(SCC(=O)NC23CC4CC(CC(C4)C2)C3)n(N)c1=O CHEMBL1423952 Potency 4.0 nM
Cc1ccc(S(=O)(=O)N2N=C3CCCCC3C2(O)C(F)(F)F)cc1 CHEMBL1609923 Potency 4.0 nM
O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F CHEMBL917 Potency 4.0 nM
O=C(Nc1ncc2c(n1)CC(c1ccco1)CC2=O)c1ccco1 CHEMBL1401415 Potency 4.0 nM
CCOc1ccc(S(=O)(=O)NCC(c2ccco2)S(=O)(=O)c2cccs2)cc1 CHEMBL1592811 Potency 4.0 nM
COc1cc(OC)nc(S(C)(=O)=O)n1 CHEMBL1410645 Potency 4.0 nM
CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 CHEMBL8747 Potency 4.0 nM
CCC(CC)NC(=O)CO/N=C/c1ccccc1OC(F)F CHEMBL3214127 Potency 4.0 nM
COc1ccc(CC(=O)NC2CC(=O)N(c3ccc4c(c3)OCCO4)C2)cc1 CHEMBL1354419 Potency 4.0 nM
NS(=O)(=O)c1cc(C(=O)O)cc(N2CCCC2)c1Oc1ccccc1 CHEMBL349803 Potency 4.0 nM
COc1ccccc1Oc1ccc(N/C=C/C(=O)C(C)(C)C)cc1 CHEMBL1432076 Potency 4.0 nM
Cc1nccn1-c1cc(C(C)(C)C)nc2c(-c3ccccc3)cnn12 CHEMBL1312812 Potency 4.0 nM
O=C(CSc1ncccn1)N/N=C/c1ccccc1[N+](=O)[O-] CHEMBL3199928 Potency 4.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O CHEMBL1318643 Potency 4.0 nM
COc1ccc(CC(=O)NCc2nn(-c3ccccc3)nc2C)cc1OC CHEMBL1603556 Potency 4.0 nM
CCN(CC)C(=O)c1c(C)nc(S)c(C#N)c1-c1ccco1 CHEMBL1393447 Potency 4.0 nM
CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(=O)[O-])[C@H]2SC1 CHEMBL1326149 Potency 4.0 nM
COc1cccc(Oc2c(C)oc3cc(OC(=O)N(C)C)ccc3c2=O)c1 CHEMBL1607562 Potency 4.0 nM
O=Cc1ccc(Oc2ncccn2)cc1 CHEMBL1545931 Potency 4.0 nM
C[C@]12CC[C@H]3[C@@H](CCC4C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2O CHEMBL1524039 Potency 4.0 nM
Cc1cc(C)c(C(=O)CSc2nc(O)c3ccccc3n2)cc1C CHEMBL1469357 Potency 4.0 nM
Cc1nn2c(C)c(C(=O)NCc3ccc(OC(C)C)cc3)cnc2c1-c1ccc(F)cc1 CHEMBL1593429 Potency 4.0 nM
Cc1ccc(C(=O)N/C(=C/c2ccco2)C(=O)NC2CCS(=O)(=O)C2)cc1 CHEMBL1326947 Potency 4.0 nM
CN(C)[C@H]1C(O)=C(C(=O)NCN2CCCC2)C(=O)[C@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3C[C@@H]12 CHEMBL1514090 Potency 4.0 nM
Cc1ccccc1N1C(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N[C@H]1C CHEMBL1356161 Potency 4.0 nM
CCOC(=O)c1sc(NC(=O)Cc2ccc(C)cc2)nc1C CHEMBL1309410 Potency 4.0 nM
CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O CHEMBL1396177 Potency 4.0 nM
NC(=O)N1c2ccccc2C=Cc2ccccc21 CHEMBL108 Potency 4.0 nM
O=C(c1ccccc1Br)N1CCCS/C1=N\c1ccccc1 CHEMBL3193433 Potency 4.0 nM
CCOC(=O)C1CCCN(CCC(=O)Nc2ccc(C)c(C)c2)C1 CHEMBL1428899 Potency 4.0 nM
O=C1CC(c2ccccc2)CN1C(=O)c1cccc([N+](=O)[O-])c1 CHEMBL1497648 Potency 4.5 nM
CCOc1ccc(C(=O)c2ccccc2C(=O)O)cc1OCC CHEMBL1458193 Potency 4.5 nM
O=C(c1ccccc1)c1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1536878 Potency 4.5 nM
Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)cc1 CHEMBL1319259 Potency 4.5 nM
O=C(NCCS(=O)(=O)N1CCN(c2ccccc2F)CC1)c1ccccc1C(F)(F)F CHEMBL1592192 Potency 4.5 nM
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL34259 Potency 4.5 nM
O=C(NCc1c(Cl)cccc1Oc1ccccc1)c1ccccc1 CHEMBL1300215 Potency 4.5 nM
COc1ccccc1NC(=O)COC(=O)C1CCN(/C=C/C(=O)C(F)(F)F)CC1 CHEMBL1448947 Potency 4.5 nM
CN(C)C(=O)Oc1cccc([N+](C)(C)C)c1 CHEMBL54126 Potency 4.5 nM
O=[N+]([O-])c1ccc(C[n+]2cccc3c4ccccc4ccc32)cc1 CHEMBL1448922 Potency 4.5 nM
COc1cc(C(C(=O)NC2CCCCC2)N(Cc2ccco2)C(=O)c2cnccn2)cc(OC)c1OC CHEMBL1330461 Potency 4.5 nM
O=C(OCC(=O)N1CCN(C(=O)c2ccco2)CC1)c1ccccc1OCc1ccccc1 CHEMBL1565076 Potency 4.5 nM
Cc1ccc2cc(N)ccc2n1 CHEMBL1399676 Potency 4.5 nM
S=C(NCc1ccco1)Nc1ccc(Br)cc1Cl CHEMBL1408580 Potency 4.5 nM
O=C(Nc1nc(-c2ccc(Br)cc2)cs1)c1cccnc1 CHEMBL1438821 Potency 4.5 nM
Cc1ccc(O)c(/N=C/c2ccc(C)s2)c1 CHEMBL3209299 Potency 4.5 nM
CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1 CHEMBL1257078 Potency 4.5 nM
CCN(C(=O)CN1CCN(S(=O)(=O)c2cc(Cl)ccc2Cl)CC1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O CHEMBL1577779 Potency 4.5 nM
CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)[O-])c1I CHEMBL1200581 Potency 4.5 nM
O=C(CSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)Nc1nccs1 CHEMBL1301937 Potency 4.5 nM
Cc1cccc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)c1 CHEMBL1568518 Potency 4.5 nM
NC(=O)c1ccc(N2CCN(c3ccccc3O)CC2)c([N+](=O)[O-])c1 CHEMBL1460348 Potency 4.5 nM
Cc1cc(S)nc(S)n1 CHEMBL1420427 Potency 4.5 nM
Cc1cc(C)c2c(NC(=O)c3ccccc3)c(C(=O)Nc3ccc(F)cc3)sc2n1 CHEMBL1606562 Potency 4.5 nM
CCc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCCC3)c[nH]2)cc1 CHEMBL1356908 Potency 4.5 nM
CC(Oc1ccc(F)cc1)C(=O)N1CCC(c2nc3ccccc3s2)CC1 CHEMBL1371914 Potency 4.5 nM
CC(C)C(N=C(S)Nc1ccccc1)C(=O)O CHEMBL1360854 Potency 4.5 nM
O=C(CN1C(=O)C2C3CCC(C3)C2C1=O)N1CCN(Cc2ccccc2)CC1 CHEMBL1489180 Potency 4.5 nM
COc1ccc(C2SCCN2S(=O)(=O)c2ccccc2)cc1 CHEMBL1499371 Potency 4.5 nM
Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 CHEMBL104 Potency 4.5 nM
CCOC(=O)C(/C=N/c1ccc(OC)cc1[N+](=O)[O-])=C(/O)OCC CHEMBL3197809 Potency 4.5 nM
NC12CC3CC(CC(C3)C1)C2 CHEMBL1569 Potency 4.5 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2Cc1ccc(Cl)cc1 CHEMBL1256814 Potency 4.5 nM
NCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 CHEMBL1526455 Potency 4.5 nM
COCCn1/c(=N/C(=O)/C=C/c2ccccc2)sc2cc(NC(C)=O)ccc21 CHEMBL3208257 Potency 4.5 nM
Nc1nc2[nH]c(=O)cnc2c(=O)[nH]1 CHEMBL464251 Potency 4.5 nM
CC(=O)N1CCN(c2nc(CC(C)C)c3c(c2C#N)CCC3)CC1 CHEMBL1360638 Potency 4.5 nM
C/C(N)=C(/C#N)C(=O)CSc1nnc(Nc2c(C)cccc2C)s1 CHEMBL3391890 Potency 4.5 nM
CN1CCC[C@@H]1c1cccnc1 CHEMBL9732 Potency 4.5 nM
COc1cc2c(C(=O)N3CCN(C)CC3)c(C)n(C)c2cc1Br CHEMBL1341829 Potency 4.5 nM
C=C1c2c(Cl)ccc(O)c2C(=O)C2=C(O)[C@@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12 CHEMBL1596361 Potency 4.5 nM
COc1cccc(/C=C/C(=O)OCC(=O)Nc2cccc(S(=O)(=O)N3CCOCC3)c2)c1OC CHEMBL1578092 Potency 4.5 nM
CCc1ccc(CNC(=O)CN2C(=O)CSc3c2c(C)nn3-c2ccccc2)cc1 CHEMBL1518444 Potency 4.5 nM
Cc1cc(C)c2nc(SCC(=O)N(C)C3CCS(=O)(=O)C3)cc(C)c2c1 CHEMBL1539183 Potency 4.5 nM
O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccc(F)cc1 CHEMBL1440044 Potency 4.5 nM
Cc1cc(C)cc(OCC(=O)N2CCC(c3nc4ccccc4s3)CC2)c1 CHEMBL1356643 Potency 4.5 nM
COCCN(CCOC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(COC)o2)cc1 CHEMBL1379293 Potency 4.5 nM
CC(=O)N1CCN(CCNC=C2C(=O)CC(c3ccc(Cl)cc3)CC2=O)CC1 CHEMBL3193498 Potency 4.5 nM
COc1cc(OC)cc(C(=O)Nc2ccc(CN3CCCCC3)cc2)c1 CHEMBL1339646 Potency 4.5 nM
COc1cc(O)ccc1/C=N/NC(=O)c1ccc([N+](=O)[O-])cc1 CHEMBL3189375 Potency 4.5 nM
Cn1nc(C(F)(F)F)c(C(=O)Nc2ccc(F)cc2F)c1Cl CHEMBL1333789 Potency 4.5 nM
COc1ccc(C(=S)N2CCCCC2)cc1Br CHEMBL1414212 Potency 4.5 nM
Cc1ccc(-c2c3c(=O)n(C)c(=O)n(C)c3cn2Cc2cccnc2)cc1 CHEMBL1597470 Potency 4.5 nM
CCOC(=O)c1oc2ccccc2c1NC(=O)CN1CCOCC1 CHEMBL1303920 Potency 4.5 nM
Cc1ccc(NC(=O)C[S+]([O-])CC(=O)N(C(C)C(=O)NC2CCCCC2)C(C)(C)C)cc1 CHEMBL1520375 Potency 4.5 nM
COC(=O)C1=C(C)NC(C)=C([N+](=O)[O-])C1c1ccccc1C(F)(F)F CHEMBL1082832 Potency 4.5 nM
NS(=O)(=O)c1cccc(-n2cnnn2)c1 CHEMBL1571866 Potency 4.5 nM
CC(NC(=O)c1cc(-c2ccccc2)nc2ccccc12)C1CCCO1 CHEMBL1454333 Potency 4.5 nM
O=C1NC(=O)N(c2ccccc2)C(=O)/C1=C\NN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL1481714 Potency 4.5 nM
COC(=O)C1=C(C)N(C)C(S)=NC1c1ccc(Cl)cc1 CHEMBL1403169 Potency 4.5 nM
CC[N+](CC)(CC(=O)Nc1c(C)cccc1C)Cc1ccccc1 CHEMBL1371493 Potency 4.5 nM
CCOC(=O)O[C@]1(C(=O)COC(=O)CC)CC[C@@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C)[C@H]3[C@H](O)C[C@]21C CHEMBL1397466 Potency 4.5 nM
COc1cccc(CN2CCN(C(=O)c3ccc(-c4ccccc4)cc3)CC2)c1 CHEMBL1542910 Potency 4.5 nM
COCCNC(=O)/C(C#N)=C/c1ccc(C(=O)O)cc1 CHEMBL1306291 Potency 4.5 nM
O=C(NCCC1=CCCCC1)C1COc2ccccc2O1 CHEMBL1346286 Potency 4.5 nM
COc1cc2nc(CN3C(=O)c4ccccc4C3=O)oc(=O)c2cc1OC CHEMBL1450287 Potency 4.5 nM
COP(=O)(CC(=O)c1ccccc1)CC(=O)c1ccccc1 CHEMBL1504098 Potency 4.5 nM
Cc1ccccc1NC(=O)CN1C(=O)N/C(=C\c2cccn2-c2cccc(C(=O)O)c2)C1=O CHEMBL1346592 Potency 4.5 nM
COc1cc(-c2ccno2)ccc1S(=O)(=O)N1CCN(c2cccc(Cl)c2)CC1 CHEMBL1482136 Potency 4.5 nM
CCCCCCCCCC(=O)NC(CN1CCOCC1)[C@H](O)c1ccccc1 CHEMBL1534566 Potency 4.5 nM
COC(=O)c1ccc(OCC(O)CN(CCO)CCO)cc1 CHEMBL1324241 Potency 4.5 nM
O=C(Nc1ccc(OCc2ccccc2)cc1)c1cccc([N+](=O)[O-])c1 CHEMBL404214 Potency 4.5 nM
COc1cc(/C=N/NC(=O)C2CCN(CC(O)COCc3ccccc3)CC2)ccc1O CHEMBL3213453 Potency 4.5 nM
COc1cc(Cl)c(C)cc1NC(=O)c1cnc2c(-c3cccc(C)c3)c(C)nn2c1C CHEMBL1377237 Potency 4.5 nM
Cn1c(=O)[nH]c2ncn(C)c2c1=O CHEMBL1158 Potency 4.5 nM
CCOC(=O)c1ccc(NP(C)(=O)Oc2cc(C)cc(C)c2)cc1 CHEMBL1568430 Potency 4.5 nM
CCCN1C2CCCC1CC(N=C(S)Nc1ccc(OC)cc1)C2 CHEMBL1417178 Potency 4.5 nM
Cc1ccc2nc(NC(=O)CCn3cccc3)sc2c1 CHEMBL1324408 Potency 4.5 nM
Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCC5(CC4)OCCO5)cc3c2C)cc1Cl CHEMBL1397616 Potency 4.5 nM
C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL241694 Potency 4.5 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL1448187 Potency 4.5 nM
Cc1cc(C)n(CCN(C)Cc2nc(Cc3ccccc3F)no2)n1 CHEMBL1572778 Potency 4.5 nM
COc1ccc(NC(=O)CSc2nc(O)cc(=O)n2-c2ccccc2OC)cc1 CHEMBL1599659 Potency 4.5 nM
Cc1cccc(NC(=S)/N=C(\N)Nc2nc(C)c3cc(C)ccc3n2)c1 CHEMBL1573368 Potency 4.5 nM
CN(Cc1nccn1C)C(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1 CHEMBL1611943 Potency 4.5 nM
CN(C(=O)c1cc(-n2cnnc2)ccc1Cl)c1ccccc1 CHEMBL1505121 Potency 4.5 nM
O=[N+]([O-])c1cc(S(=O)(=O)NC2=NCCCCC2)ccc1Cl CHEMBL1495475 Potency 4.5 nM
C=CC1=C2C=C(C3CC3)N(CCCN(CC)CC)C=C2C(=O)C(C)(OC(=O)c2ccco2)C1=O CHEMBL1573076 Potency 4.5 nM
COc1ccc(-c2cc(C(C)=O)c(C)n2CCC(=O)Nc2cccc(C)c2C)cc1 CHEMBL1483093 Potency 4.5 nM
COc1cc(C(=O)OCC(=O)Nc2c(F)cccc2F)cc(OC)c1C CHEMBL1505401 Potency 4.5 nM
O=C(COC(=O)c1cc(O)nc2ccccc12)NC1CCCC1 CHEMBL1582669 Potency 4.5 nM
Cc1cn2c(=O)cc(COC(=O)c3cccc(NC(=O)COc4ccccc4)c3)nc2s1 CHEMBL1364914 Potency 4.5 nM
COc1ccc(-c2noc(-c3ccccc3C(=O)Nc3cccc(OC)c3)n2)cc1 CHEMBL1347752 Potency 4.5 nM
CC(C)(C)C(=O)/C=C/c1ccc(Oc2ccccc2)cc1 CHEMBL1995296 Potency 4.5 nM
Cc1oncc1C(=O)NC1CCCCC1 CHEMBL1347683 Potency 4.5 nM
Oc1nc(CSc2nnnn2-c2ccc(Cl)cc2)nc2ccccc12 CHEMBL1365158 Potency 4.5 nM
Cc1cc(C(=O)NCC2COc3ccccc3O2)c2ccccc2n1 CHEMBL1462365 Potency 4.5 nM
CC(C)CCNC(=O)c1ccc2c(c1)N(C)C(=O)c1ccccc1S2 CHEMBL1609496 Potency 4.5 nM
O=C(CC12CC3CC(CC(C3)C1)C2)NC(Cc1ccccc1)C(=O)O CHEMBL1384868 Potency 4.5 nM
O=c1ccc2cc3c4c(c2o1)CCCN4CCC3 CHEMBL1345017 Potency 4.5 nM
CC(=O)Nc1ccc(NC(=O)CSc2nnc(-c3ccc(NS(C)(=O)=O)cc3)n2C)cc1C CHEMBL1539380 Potency 4.5 nM
Cn1c(=O)c2c(nc(N/N=C/c3cccs3)n2Cc2ccccc2)n(C)c1=O CHEMBL3195828 Potency 4.5 nM
CC(=O)c1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2ccccc2)cc1 CHEMBL1557926 Potency 4.5 nM
CCS(=O)(=O)c1cccc(C(=O)N2CCN(c3nc4c(C)ccc(Cl)c4s3)CC2)c1 CHEMBL1401550 Potency 4.5 nM
O=C(NCc1ccccc1)c1ccccc1CO CHEMBL1461691 Potency 4.5 nM
Cc1c(Cl)cccc1N=C(S)N1CCc2ccccc2C1 CHEMBL1566662 Potency 4.5 nM
CNCCNS(=O)(=O)c1cccc2cnccc12 CHEMBL1395058 Potency 4.5 nM
COC(=O)c1ccc(NC(S)=Nc2ccc(O)cc2)cc1 CHEMBL1304886 Potency 4.5 nM
Cc1ccc(C(=O)N2CCN(c3ccccn3)CC2)cc1[N+](=O)[O-] CHEMBL1605820 Potency 4.5 nM
Cc1[nH]c2ccccc2c1/C=N/Nc1ccccn1 CHEMBL3208210 Potency 4.5 nM
O/N=C1\CCCC\C1=C/c1ccccc1 CHEMBL3212200 Potency 4.5 nM
COc1cc(S(=O)(=O)N2CCN(C(=O)c3ccccc3)CC2)c(OC)cc1Br CHEMBL1382501 Potency 4.5 nM
COc1ccc(S(=O)(=O)NCCc2csc3nc(-c4cccc(C)c4)nn23)cc1F CHEMBL1607916 Potency 4.5 nM
Cc1nn(Cc2cccc(Oc3ccccc3)c2)c(C)c1NC(=O)NC12CC3CC(CC(C3)C1)C2 CHEMBL1441399 Potency 4.5 nM
O=C(C1COc2cc(S(=O)(=O)Nc3ccc(Cl)cc3)ccc2O1)N1CCCC1 CHEMBL1609543 Potency 4.5 nM
O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)c1cccs1 CHEMBL1502908 Potency 4.5 nM
Cc1cc(=O)oc2cc(OCCSCCN3CCCCC3)ccc12 CHEMBL1422935 Potency 4.5 nM
CC[C@@H]1O[C@]2(C=C[C@@H]1C)C[C@H]1C[C@H](C/C=C(\C)[C@@H](O[C@@H]3C[C@H](OC)[C@H](O[C@@H]4C[C@H](OC)[C@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)/C=C/C=C3CO[C@@H]4[C@@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2 CHEMBL1436151 Potency 4.5 nM
COc1ccccc1C(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C CHEMBL1501476 Potency 4.5 nM
O=C(CSc1ccccn1)N1CCc2ccccc21 CHEMBL1413808 Potency 4.5 nM
Cc1cc(C(=O)CC#N)c(C)n1-c1c(C)n(C)n(-c2ccccc2)c1=O CHEMBL1453645 Potency 4.5 nM
Cc1cc(C)n2nc(S(=O)(=O)N(C)Cc3ccccc3)nc2n1 CHEMBL1442090 Potency 4.5 nM
Cc1ccc(NC(=O)CSc2nnc(Cc3cccn3C)n2-c2ccc(F)cc2)cc1 CHEMBL1449760 Potency 4.5 nM
CCCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccc(N4CCOCC4)c(Cl)c3)sc2c1 CHEMBL1361455 Potency 4.5 nM
Nn1c(SCC(=O)Nc2ccc3c(c2)OCO3)nncc1=O CHEMBL1578552 Potency 4.5 nM
O=C(C1CCC(Cn2c(=O)c3sccc3n(Cc3ccccc3F)c2=O)CC1)N1CCOCC1 CHEMBL1608155 Potency 4.5 nM
COc1ccc(-c2[nH]ncc2CN2CCN(c3ccc(F)cc3)CC2)cc1 CHEMBL1342914 Potency 4.5 nM
COCCNC(=O)C(c1ccco1)N(Cc1ccc(OC)cc1)C(=O)Cn1nnc2ccccc21 CHEMBL1597267 Potency 4.5 nM
O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N1CCCCCC1 CHEMBL1453567 Potency 4.5 nM
C=CCN1C(=O)/C(=c2\sc3nc(=O)c(Cc4ccccc4Cl)nn3c2=O)c2ccccc21 CHEMBL3194416 Potency 4.5 nM
Cc1ccc(C(=O)NC2CCN(CC(=O)NCc3cccs3)CC2)cc1 CHEMBL1462858 Potency 4.5 nM
O=C(NC(=S)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)c1ccco1 CHEMBL1454186 Potency 4.5 nM
O=C1NC(=O)N(C2CCCCC2)C(=O)/C1=C/Nc1ccc(N2CCOCC2)cc1 CHEMBL1343877 Potency 4.5 nM
COc1cccc(-n2nnc3c(=O)n(CC(=O)N4CCC(Cc5ccccc5)CC4)cnc32)c1 CHEMBL1570468 Potency 4.5 nM
Cc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4ccsc4n3)c2)c1 CHEMBL1513126 Potency 4.5 nM
COc1cc(OC)c(NC(=O)CCn2cnc3onc(-c4ccc(F)cc4)c3c2=O)cc1Cl CHEMBL1414768 Potency 4.5 nM
COC(=O)c1ccc(OCC2c3cc(OC)c(OC)cc3CCN2C(=O)COc2ccc(Cl)cc2)cc1 CHEMBL1609850 Potency 4.5 nM
Cc1nc(Nc2ccccc2)sc1-c1ccccc1 CHEMBL1503238 Potency 4.5 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1 CHEMBL1481539 Potency 4.5 nM
COc1ccc(C(=O)NCC(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1OC CHEMBL1609161 Potency 4.5 nM
O=S(=O)(c1cccs1)n1nnc2ccccc21 CHEMBL1453094 Potency 4.5 nM
CC(=O)Nc1nn(C)c2nc3cc(C)ccc3cc12 CHEMBL1580210 Potency 4.5 nM
CCN(CC(=O)NC(C)(C)C)C(=O)c1ccc(Br)cc1 CHEMBL1559321 Potency 4.5 nM
COC(=O)c1ccc(-c2nc3ccccc3[nH]2)cc1 CHEMBL1323490 Potency 4.5 nM
Cc1ccc(C(=O)N/N=C/C2=Cc3ccccc3OC2C)cc1 CHEMBL3199095 Potency 4.5 nM
CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O CHEMBL86676 Potency 4.5 nM
COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1 CHEMBL1593765 Potency 4.5 nM
CCn1cc(Br)c(C(=O)NC(=S)Nc2ccc(C(=O)OC)cc2)n1 CHEMBL1574873 Potency 4.5 nM
CNCC[C@H](Oc1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL1257031 Potency 4.5 nM
COc1cccc(CC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2Cl)c1 CHEMBL1474713 Potency 4.5 nM
CCOC(=O)Cc1cc(O)n2ncc(-c3ccc(Cl)cc3)c2n1 CHEMBL1547874 Potency 4.5 nM
O=C(NNC(=O)c1cccc(Br)c1)C(=O)N1CCCCC1 CHEMBL1431216 Potency 4.5 nM
CC1(C)Cc2ccccc2C(NN=C2CCCC2)=N1 CHEMBL1327927 Potency 4.5 nM
Cc1cc(NC(=O)CSc2nnc(C(C)N(C)C)n2Cc2ccccc2)no1 CHEMBL1549083 Potency 4.5 nM
Cc1c(C(=O)N2CCCCCC2)c(S(=O)(=O)N(Cc2ccccc2)C(C)(C)C)c(C)n1C CHEMBL1356563 Potency 4.5 nM
CNC(=O)/C(=C/c1ccc2c(c1)OCO2)NC(=O)c1ccc(Br)cc1 CHEMBL1392247 Potency 4.5 nM
O=C(Oc1ccc2ccc(=O)oc2c1)c1cccs1 CHEMBL1312419 Potency 4.5 nM
O=C1OC(c2ccccc2)=N/C1=C\C=C\c1ccco1 CHEMBL1392335 Potency 4.5 nM
CCN(CC)C(=O)Nc1cnc2ccccc2c1 CHEMBL1525407 Potency 4.5 nM
O=C(CSC1=NCCN1)Nc1cccc(C(F)(F)F)c1 CHEMBL1352394 Potency 4.5 nM
CC(C)(C)NC(=O)CN(C(=O)C1CSC(=O)C1)c1ccccc1F CHEMBL1312545 Potency 4.5 nM
CC(C)=CC(=O)Nc1nnc(-c2ccccc2C)s1 CHEMBL1549301 Potency 4.5 nM
CC(C)Cc1nn2c(=O)cc(COC(=O)c3cccc(NS(C)(=O)=O)c3)nc2s1 CHEMBL1512169 Potency 4.5 nM
COc1cc(/C=N/N=C(N)N)ccc1OCc1ccccc1Cl CHEMBL3211420 Potency 4.5 nM
O=C(CCc1nc(-c2ccccc2F)no1)NCCN1CCc2ccccc2C1 CHEMBL1312857 Potency 4.5 nM
CCc1cccc(NC(=O)CSc2ncccc2C(=O)Oc2ccccc2Cl)c1 CHEMBL1514268 Potency 4.5 nM
O=C(NCCSc1ccccn1)c1ccc(Cl)cc1Cl CHEMBL1549852 Potency 4.5 nM
COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]2c3cc(C(=O)N(C)C)n(CCSCCO)c3C[C@H]2CN1C(=O)c1ccccc1 CHEMBL1564813 Potency 4.5 nM
O=C(CCl)c1ccc2c(c1)CCN2C(=O)C1CCCCC1 CHEMBL1352919 Potency 4.5 nM
CCC(CC)C(=O)Nc1ccc2nc(SCC(=O)N3CCCC3)sc2c1 CHEMBL1407954 Potency 4.5 nM
Cc1ccc(OCC(=O)c2ccc(Cl)cc2)c(N2C(=O)CCCC2=O)c1 CHEMBL1471670 Potency 4.5 nM
Cc1cc([N+](=O)[O-])ccc1NC(=O)C[n+]1ccc(N(C)C)cc1 CHEMBL1603671 Potency 4.5 nM
Cc1cc(=O)oc2cc(O)ccc12 CHEMBL12208 Potency 4.5 nM
COc1ccc(OC)c(NC(=O)CC2C(=O)NCCN2C(=O)C(F)(F)F)c1 CHEMBL1474951 Potency 4.5 nM
CC(=O)c1ccc(N2CCN(C(=O)Nc3ccc(Cl)cc3)CC2)cc1 CHEMBL547977 Potency 4.5 nM
O=[N+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17331 Potency 4.5 nM
CCc1ccccc1NC1=NCC(=O)N1C1CCCCC1 CHEMBL1456289 Potency 4.5 nM
CC1Sc2ccc(Cl)cc2-c2nc(N)ncc21 CHEMBL1583676 Potency 4.5 nM
O=C(O)c1ccc(-c2ccc(O)c(F)c2)cc1 CHEMBL1417963 Potency 4.5 nM
CCOC(=O)C1C(c2cc(OC)c(OC)c(OC)c2)N=C(S)NC1(O)C(F)(F)F CHEMBL1584552 Potency 4.5 nM
O=C(c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1)N1CCN(c2ncccn2)CC1 CHEMBL1428529 Potency 4.5 nM
Cn1c(C(C#N)C(=O)c2ccco2)nc2ccccc21 CHEMBL1418531 Potency 4.5 nM
COc1ccc(Oc2ccc(NC(=O)c3ccccc3C)cc2)cc1 CHEMBL1536110 Potency 4.5 nM
COc1ccccc1NC(=O)C(C)Sc1nnc2ccc3ccccc3n12 CHEMBL1591805 Potency 4.5 nM
CCc1cccc(CC)c1C(O)c1cccnc1 CHEMBL1586520 Potency 4.5 nM
Cc1ccc(C)c(N2C(=O)N(Cc3ccccc3C)c3ccccc3S2(=O)=O)c1 CHEMBL1476745 Potency 4.5 nM
CN(C)c1cc2c(Nc3ccc4c(cnn4Cc4ccccc4)c3)ncnc2cn1 CHEMBL30432 Potency 4.5 nM
CN(N=O)c1cc(O)ccc1O CHEMBL269733 Potency 4.5 nM
CCOC(=O)C1(CCc2ccccc2)CCN(Cc2ccc(O)cc2)CC1 CHEMBL1495780 Potency 4.5 nM
COC(=O)c1cccc(NC(=O)CN(c2ccc3c(c2)OCO3)S(C)(=O)=O)c1C CHEMBL1535570 Potency 4.5 nM
CC1Oc2ccccc2N(CC(=O)NCC2CCCO2)C1=O CHEMBL1523701 Potency 4.5 nM
Cc1ccc(-n2ncc3c(N(C)Cc4ccccc4)ncnc32)cc1 CHEMBL1318128 Potency 4.5 nM
COc1ccc(CNC(=O)Cn2c(=O)oc3cc(S(=O)(=O)N4CCCCCC4)ccc32)cc1 CHEMBL1523598 Potency 4.5 nM
CCn1c(S)nnc1-c1csc(C(C)C)c1 CHEMBL1405862 Potency 4.5 nM
Nc1ccccc1Sc1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL1585551 Potency 4.5 nM
COc1ccc([N+](=O)[O-])cc1NC(C)C CHEMBL1406519 Potency 4.5 nM
Fc1cccc(F)c1/C=N/Nc1ccccn1 CHEMBL3193230 Potency 4.5 nM
COc1ccc2c(C#N)c3ccccn3c2c1 CHEMBL1309254 Potency 4.5 nM
CCOC(=O)C(C(=O)OCC)N(C#N)c1nc(N(C)C)nc(N(C)C)n1 CHEMBL1535716 Potency 4.5 nM
Cc1cccc2[nH]c(CN(C)Cc3nc(CC4CC4)no3)nc12 CHEMBL1546913 Potency 4.5 nM
O=C(Nc1ccccc1N1CCOCC1)C1(c2ccc(Cl)cc2)CCC1 CHEMBL1350098 Potency 4.5 nM
Cc1cc(C)cc(-n2ccn(CC(=O)NCCc3ccccc3)c(=O)c2=O)c1 CHEMBL1569461 Potency 4.5 nM
COc1cccc(NC(=O)C(=O)NCc2ccncc2)c1 CHEMBL1391470 Potency 4.5 nM
O=C(CN1CCN(S(=O)(=O)c2ccccc2)CC1)Nc1ccc2c(c1)CCC2 CHEMBL1602503 Potency 4.5 nM
CCc1ccc(C(=O)OCC(=O)NCC(F)(F)F)cc1 CHEMBL1483869 Potency 4.5 nM
Brc1ccc(OCCOc2cccc3cccnc23)cc1 CHEMBL1308622 Potency 4.5 nM
COc1cc(/C=C(\NC(C)=O)C(=O)O)cc(OC)c1OC CHEMBL1429587 Potency 4.5 nM
COCC(C)NC1=NN=C(c2c[nH]c3ccccc23)CS1 CHEMBL1547170 Potency 4.5 nM
CN(Cc1nccn1C)C(=O)CCc1nnc(CCC2CCCCC2)o1 CHEMBL1367066 Potency 4.5 nM
O=[N+]([O-])c1cccc(C2=NCCS2)c1 CHEMBL1483822 Potency 4.5 nM
Ic1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 CHEMBL1496166 Potency 4.5 nM
C[C@H]1CC2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO CHEMBL1435313 Potency 4.5 nM
Cc1cc[n+](C2=Nc3ccccc3[N-]C2=C(C#N)C#N)cc1 CHEMBL1350532 Potency 4.5 nM
CCCC(=O)NCC1(N(C)C)CCCCC1 CHEMBL1551123 Potency 4.5 nM
CCc1ccc(CNC(=O)c2ccc(NC(=O)N3CCCCc4ccccc43)cc2)cc1 CHEMBL1602762 Potency 4.5 nM
CCOC(=O)C1(CCc2ccccc2)CCN(C(=O)Cc2nonc2C)CC1 CHEMBL1389604 Potency 4.5 nM
COc1ccccc1N(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)N2CCCCCC2)cc1 CHEMBL1350459 Potency 4.5 nM
O=C(CCc1nc(-c2cccs2)no1)Nc1ccccc1[N+](=O)[O-] CHEMBL1563373 Potency 4.5 nM
c1ccc2c(c1)CC(N1CCN(c3cccc4c3OCCO4)CC1)C2 CHEMBL49247 Potency 4.5 nM
Cc1nnc(SCc2cccc([N+](=O)[O-])c2)s1 CHEMBL1531097 Potency 4.5 nM
O=C(N/N=C/c1cccc(Oc2ccccc2)c1)c1cc[n+]([O-])cc1 CHEMBL3195786 Potency 4.5 nM
CCCN1CCC(NC(=O)CCc2nnc(Cc3cc(OC)ccc3OC)o2)CC1 CHEMBL1467257 Potency 4.5 nM
Cc1sc2nc(CC(N)=O)nc(O)c2c1-c1ccccc1 CHEMBL1417715 Potency 4.5 nM
CN1CCN(C2=Nc3ccccc3Oc3ccc(Cl)cc32)CC1 CHEMBL1201155 Potency 4.5 nM
Cc1cc(C)n(-c2nc3ccccc3c(=O)n2OCC(=O)N(C)C)n1 CHEMBL1547579 Potency 4.5 nM
Cc1ccc(NC(=O)COC(=O)c2ccc(Cl)cc2)cc1S(=O)(=O)N(C)C CHEMBL1469119 Potency 4.5 nM
O=C(OCC(=O)N1CCc2ccccc21)c1cncc(Br)c1 CHEMBL1548758 Potency 4.5 nM
C=C(C)C1CC=C(C(=O)O)CC1 CHEMBL1373981 Potency 4.5 nM
CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O CHEMBL15192 Potency 5.0 nM
CCN1CCN(CCCN(Cc2ccco2)C(S)=Nc2ccc(Cl)cc2)CC1 CHEMBL1299858 Potency 5.0 nM
CCCCc1nn2c(=O)cc(COC(=O)Cc3ccccc3)nc2s1 CHEMBL1566349 Potency 5.0 nM
COc1ccc(C)cc1S(=O)(=O)N(CC(=O)Nc1cccc([N+](=O)[O-])c1)c1ccc(C)cc1 CHEMBL1537219 Potency 5.0 nM
COC(=O)c1ccncc1C(=O)Nc1ccc(OC)cc1 CHEMBL1340222 Potency 5.0 nM
COC(=O)c1ccc(CNC(=O)COC(=O)Cc2ccsc2)cc1 CHEMBL1576081 Potency 5.0 nM
CCn1cc(C(=O)NCc2ccccc2Cl)cn1 CHEMBL1488404 Potency 5.0 nM
O=C(N/N=C/c1ccc(Br)o1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 CHEMBL3195530 Potency 5.0 nM
O=C(CCc1ccc(O)cc1)c1c(O)cc(O)cc1O CHEMBL45068 Potency 5.0 nM
Cc1oc(-c2ccc(Cl)cc2)nc1Cn1c(=O)cc(C)c2c(C)nn(-c3cccc(F)c3)c21 CHEMBL1473142 Potency 5.0 nM
CCOc1cc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc(OCC)c1OCC CHEMBL1319614 Potency 5.0 nM
O=C(CN(Cc1cccs1)S(=O)(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1)Nc1ccccc1 CHEMBL1448934 Potency 5.0 nM
CCOC(=O)c1nn(-c2ccc(F)cc2)cc1O CHEMBL1537402 Potency 5.0 nM
Cc1cc(=O)oc2cc(OC(=O)CCN3C(=O)c4ccccc4C3=O)ccc12 CHEMBL1458939 Potency 5.0 nM
CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C CHEMBL1200330 Potency 5.0 nM
COC(=O)c1ccc(NC(=O)CSc2nnc(COc3ccc4c(c3)CCCC4)o2)cc1 CHEMBL1439001 Potency 5.0 nM
Cn1c(=O)c2nc(C3CCCC3)[nH]c2n(C)c1=O CHEMBL106265 Potency 5.0 nM
CCCS(=O)(=O)N1CCC(Cc2ccc(OC)cc2)(C(=O)OCC)CC1 CHEMBL1498640 Potency 5.0 nM
CCOC(=O)CC1ON(C)C(=O)N1c1ccc([N+](=O)[O-])cc1 CHEMBL1499139 Potency 5.0 nM
CNC(=O)CCCN1C(=O)c2cccnc2Sc2ccccc21 CHEMBL1394739 Potency 5.0 nM
Cc1ccc(C2CC(c3cccs3)=NN2C(=O)c2ccco2)o1 CHEMBL1460265 Potency 5.0 nM
O=C(O)C1CN(CCCP(=O)(O)O)CCN1 CHEMBL22304 Potency 5.0 nM
Cc1cnc(C(=O)Nc2ccc(S(=O)(=O)NCC(C)C)cc2)cn1 CHEMBL1380951 Potency 5.0 nM
O=C(NCc1ccccc1)C1CC(=O)N(C2CCCCCC2)C1 CHEMBL1320403 Potency 5.0 nM
CCOC(=O)c1[nH]c(C)c(C(=O)NCc2ccco2)c1C CHEMBL1342146 Potency 5.0 nM
Clc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 CHEMBL555670 Potency 5.0 nM
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)([O-])OP(=O)([O-])[O-])[C@H](O)[C@H]3O)c2n1 CHEMBL1396782 Potency 5.0 nM
CC(COc1ccccc1)N(CCCl)Cc1ccccc1 CHEMBL1200787 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccc(OC)cc2)n(CCC(=O)Nc2ccc(OC)cc2OC)c1C CHEMBL1557310 Potency 5.0 nM
C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO CHEMBL253144 Potency 5.0 nM
COc1cc(/C=N/NC(=S)NCc2ccco2)cc(OC)c1OC CHEMBL3207361 Potency 5.0 nM
OC(CN1CCN(c2cccc(Cl)c2)CC1)C(c1ccccc1)c1ccccc1 CHEMBL534084 Potency 5.0 nM
O=C(CCCCCNC(=O)c1ccccc1Br)N=Nc1c(O)[nH]c2ccccc12 CHEMBL1460737 Potency 5.0 nM
CC(C)(C)NC(=O)NC(=O)COC(=O)c1c(F)cccc1Cl CHEMBL1538274 Potency 5.0 nM
COc1ccc(-c2nc3ccccc3c(=O)o2)cc1 CHEMBL1538279 Potency 5.0 nM
Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 CHEMBL165 Potency 5.0 nM
COc1ccc(CCNC(=O)c2cnn(-c3cccc(C)c3)c2C2CCNCC2)cc1OC CHEMBL1516377 Potency 5.0 nM
Cc1ccc(C(=O)NCCn2ccc3ccccc32)cc1[N+](=O)[O-] CHEMBL1575312 Potency 5.0 nM
COc1cc(CCN)ccc1O CHEMBL1448326 Potency 5.0 nM
Nn1c(SCc2ccc(Br)cc2)nnc1-c1ccccn1 CHEMBL1458098 Potency 5.0 nM
COc1cc(CNC2CCCCC2OC)cc(OC)c1 CHEMBL1448471 Potency 5.0 nM
c1cnc2c(c1)ccc1cccnc12 CHEMBL415879 Potency 5.0 nM
CCCCN(CC)C(=O)CSc1nc2nnc(C)c-2c(N)n1-c1cccc(C)c1 CHEMBL1461074 Potency 5.0 nM
COc1ccc(NC(=O)CN2C(=O)CCn3nc(-c4cccn4C)cc32)cc1 CHEMBL1335366 Potency 5.0 nM
CC(C)CC(=O)CC1(O)C(=O)Nc2ccccc21 CHEMBL1480965 Potency 5.0 nM
COc1ccc(CN2CCN(CC=C(C)C)C(CCO)C2)cc1Cn1cccn1 CHEMBL1376074 Potency 5.0 nM
CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)CC1 CHEMBL1336299 Potency 5.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL14249 Potency 5.0 nM
Cc1cc(C(=O)N/N=C2/CC(C)CC(C)(C)C2)c(C)o1 CHEMBL3191615 Potency 5.0 nM
COc1ccc(CNC2CC(=O)N(C)C2=O)cc1 CHEMBL1581724 Potency 5.0 nM
CN(C(S)=NCCN1CCOCC1)C(c1ccccc1)c1ccccc1 CHEMBL1611029 Potency 5.0 nM
CC(C)C[C@H](NC(=O)Nc1ccc(S(N)(=O)=O)cc1)C(=O)O CHEMBL1464813 Potency 5.0 nM
Cn1c2c(c(=O)c3ccccc31)CCC(C)(C)O2 CHEMBL24988 Potency 5.0 nM
CCOc1ccc(NS(=O)(=O)c2ccc(C(=O)N3CCN(c4ncccn4)CC3)cc2)cc1 CHEMBL1465529 Potency 5.0 nM
CCN1CN=C(NS(=O)(=O)c2ccc(C)cc2)NC1 CHEMBL1561636 Potency 5.0 nM
NC1(C(=O)O)CC1 CHEMBL1255660 Potency 5.0 nM
O=C(O)CCCC(=O)NCCCCc1ccccc1 CHEMBL1495289 Potency 5.0 nM
O=C(Nc1ccc(Br)cc1)c1ccc(Br)c(S(=O)(=O)N2CCCCC2)c1 CHEMBL1437086 Potency 5.0 nM
COc1ccccc1C(=O)NC(=O)CSc1cccc[n+]1[O-] CHEMBL1572910 Potency 5.0 nM
COc1ccc(S(=O)(=O)N2CCCC2c2cccs2)cc1 CHEMBL1573652 Potency 5.0 nM
C/C(=N\NC(=O)C(N)=O)c1ccc(NC(=O)c2cccs2)cc1 CHEMBL3197922 Potency 5.0 nM
O=C(/C=C/c1ccc(Cl)cc1)Nc1ccc(N2CCOCC2)cc1 CHEMBL1529760 Potency 5.0 nM
Cc1cc(C(=O)N=Nc2c(O)n(C(C)C)c3ccccc23)n[nH]1 CHEMBL1534900 Potency 5.0 nM
CCOC(=O)C1C2c3ccccc3OC1(C)N=C1SCC(=O)N12 CHEMBL1529550 Potency 5.0 nM
CCc1[nH]c(C(=O)O)c(C)c1C(=O)OC CHEMBL1455388 Potency 5.0 nM
O=C(Nc1cccnc1)c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL1527256 Potency 5.0 nM
Fc1ccc(/N=c2\ssnc2Cl)c(F)c1 CHEMBL3193771 Potency 5.0 nM
C[C@@H]1C(=O)NC2=Nc3cccc(Cl)c3CN21 CHEMBL320341 Potency 5.0 nM
Cc1c(NC(=O)c2cccnc2)c(=O)n(-c2ccccc2)n1C CHEMBL1413176 Potency 5.0 nM
CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 CHEMBL498 Potency 5.0 nM
C(=C/c1ccccc1)\CN1CCN(C(c2ccccc2)c2ccccc2)CC1 CHEMBL43064 Potency 5.0 nM
NC(=O)[C@@H]1CCNc2c(I)cc([N+](=O)[O-])cc2C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N1 CHEMBL1597546 Potency 5.0 nM
CC(=O)N1C(C)(C)CC(=NOC(=O)c2ccccc2)CC1(C)C CHEMBL1441312 Potency 5.0 nM
CCOCCOC(=O)c1ccc(-n2cnc(C)n2)nc1 CHEMBL1557931 Potency 5.0 nM
CCN(CC)c1ccc(/C=C(/C#N)C(=O)NCc2ccccc2)o1 CHEMBL1343462 Potency 5.0 nM
COc1ccc(OC)c(-n2cc3c(=O)n(C)c(=O)n(C)c3c2)c1 CHEMBL1453366 Potency 5.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O CHEMBL316966 Potency 5.0 nM
CCc1ccccc1NC(=O)c1cc(S(=O)(=O)N2CCc3ccccc32)ccc1F CHEMBL1520688 Potency 5.0 nM
OC1(c2cccnc2)CCN(Cc2nnnn2Cc2ccccc2)CC1 CHEMBL1302486 Potency 5.0 nM
COc1ccc(Cc2nc3ccc(C(=O)NCc4ccc(OC)cc4OC)cc3o2)cc1 CHEMBL1590865 Potency 5.0 nM
CCOC(=O)C1CCCN(CC(=O)Nc2cccc(C(C)=O)c2)C1 CHEMBL1424608 Potency 5.0 nM
CC(/C=N/Nc1nc2ccccc2[nH]1)=C\c1ccccc1 CHEMBL3190958 Potency 5.0 nM
NC(=O)C[C@@H]1NC(=O)c2cc([N+](=O)[O-])cc(F)c2NCCCC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC1=O CHEMBL1322776 Potency 5.0 nM
CCOC(=O)c1cnc2ncnn2c1O CHEMBL1423975 Potency 5.0 nM
Cc1ccc(C)c(NC(=O)C(=O)NCCc2csc(-c3cccc(F)c3)n2)c1 CHEMBL1454238 Potency 5.0 nM
CN(C)CCCC(C)(O)C(C)(C)c1ccccc1 CHEMBL1321347 Potency 5.0 nM
CSc1nc2ccc(NC(=O)c3nn(C(C)C)c(=O)c4ccccc34)cc2s1 CHEMBL1480234 Potency 5.0 nM
CC1Cc2ccccc2N1c1ncnc(N)c1[N+](=O)[O-] CHEMBL1414166 Potency 5.0 nM
CC(C)NNC(=O)c1ccncc1 CHEMBL1256361 Potency 5.0 nM
Cc1c(CNC(=O)C2CC2)c(-n2cccc2)n(Cc2ccccc2)c1C CHEMBL1415322 Potency 5.0 nM
O=c1c2cc(NC(=S)NC3CC3)ccc2nc2n1CCCCC2 CHEMBL1302833 Potency 5.0 nM
Cc1ccsc1C(=O)NNC(=O)C1C2C=CC(C2)C1C(=O)O CHEMBL1322174 Potency 5.0 nM
CCc1ccccc1NC(=O)C(CC)Oc1ccccc1-c1nnc(-c2ccccc2)o1 CHEMBL1315403 Potency 5.0 nM
CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H](O)[C@H]1O CHEMBL1554131 Potency 5.0 nM
Cc1ccc(-n2nc(C(=O)Nc3ccc(Br)cc3C)c(=O)n(C)c2=O)cc1 CHEMBL1403076 Potency 5.0 nM
CSc1ccccc1C(=O)NCc1ccc(F)cc1 CHEMBL1333493 Potency 5.0 nM
O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12 CHEMBL8145 Potency 5.0 nM
CCn1nc(C(=O)O)c(=O)c2cc3c(cc21)OCO3 CHEMBL1208 Potency 5.0 nM
O=C(O)CCCCCCCC(=O)O CHEMBL1238 Potency 5.0 nM
CN1C(=O)NC(c2ccc(O)cc2)C2=C1CN(c1cccc3ccccc13)C2=O CHEMBL1385281 Potency 5.0 nM
C[C@H](NC(=O)Nc1ccccc1F)C(=O)O CHEMBL1610471 Potency 5.0 nM
Nc1[nH]cnc2nc(SCc3ccccc3)nc1-2 CHEMBL1378930 Potency 5.0 nM
CC(C)N(Cc1c[nH]nc1-c1ccc(-c2ccccc2)cc1)Cc1nccn1C CHEMBL1457406 Potency 5.0 nM
O=C(C[n+]1c2n(c3ccc(C(F)(F)F)cc31)CCCCC2)Nc1ccccc1 CHEMBL1563637 Potency 5.0 nM
CN1CCN(/C=N/N=C(\C=N\O)c2ccc(F)cc2)CC1 CHEMBL3198328 Potency 5.0 nM
Clc1ccc2c(c1)C(N1CCNCC1)=Nc1ccccc1O2 CHEMBL1113 Potency 5.0 nM
CC(C)OC(=O)c1ccc(NC(=O)CSc2nc3ccc[nH]c-3n2)cc1 CHEMBL1587904 Potency 5.0 nM
COc1ccc([N+](=O)[O-])cc1-n1cnnn1 CHEMBL1510017 Potency 5.0 nM
O=c1cc(O)cc(/C=C/c2ccc(O)c(O)c2)o1 CHEMBL1224512 Potency 5.0 nM
COc1cc(-c2nc(CN3CCCN(C(=O)c4ccco4)CC3)c(C)o2)ccc1F CHEMBL1392384 Potency 5.0 nM
Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 CHEMBL1352465 Potency 5.0 nM
CC(OC(=O)Cn1c(C(F)(F)F)nc2ccccc21)C(N)=O CHEMBL1312373 Potency 5.0 nM
Cc1ccc([N+](=O)[O-])cc1NC(=O)C1CCN(S(C)(=O)=O)CC1 CHEMBL1328016 Potency 5.0 nM
O=C(CSc1ncccn1)NC(=O)Nc1ccc2c(c1)OCCO2 CHEMBL1352654 Potency 5.0 nM
COc1cccc(CNC(=O)c2ccc(NC(=O)N3CCCCc4ccccc43)cc2)c1 CHEMBL1555221 Potency 5.0 nM
NCCCP(=O)(O)O CHEMBL286077 Potency 5.0 nM
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 CHEMBL24 Potency 5.0 nM
COc1ccc(Cl)cc1NC(=O)CSc1nc(=O)[nH]c2c1CCCC2 CHEMBL1316621 Potency 5.0 nM
Fc1ccc(C2=CSC3=NCCN23)cc1 CHEMBL1393749 Potency 5.0 nM
O=S(=O)(/C=C/c1ccccc1)N1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1 CHEMBL1433148 Potency 5.0 nM
C=CCN1C(=O)NC(=O)/C(=C/c2ccc(N(C)C)c(Br)c2)C1=O CHEMBL1492623 Potency 5.0 nM
Cc1ccc(-c2cc(N)n(-c3ccc(F)cc3)n2)cc1 CHEMBL1314051 Potency 5.0 nM
CC(C)N=C(S)N1CCN(c2ncccn2)CC1 CHEMBL1444190 Potency 5.0 nM
O=C1CCCc2cc(S(=O)(=O)NCC3CCC(C(=O)NCc4ccccc4Cl)CC3)ccc2N1 CHEMBL1358260 Potency 5.0 nM
Cc1ccc(-n2ncc(C(=O)N3CCN(c4cccc(C)c4C)CC3)c2C2CCNCC2)c(C)c1 CHEMBL1437299 Potency 5.0 nM
CC(C)(C)NC[C@H](O)c1cc(Cl)c(N)c(Cl)c1 CHEMBL1396140 Potency 5.0 nM
COc1ccc(/C(C)=N\NC(=O)c2ccc3c(c2)OCO3)cc1OC CHEMBL3214113 Potency 5.0 nM
COc1cc(C2NC(=O)NC(C)=C2C(=O)OCC2CCCO2)cc(OC)c1OC CHEMBL1351064 Potency 5.0 nM
CC1CN(S(=O)(=O)c2cccc(-c3cn4cccnc4n3)c2)CC(C)O1 CHEMBL1612476 Potency 5.0 nM
CCCCNC(=O)C1CCC(CNS(=O)(=O)c2ccc(NC(C)=O)cc2)CC1 CHEMBL1319380 Potency 5.0 nM
Cc1ccc(Cl)cc1-n1ncc2c(NCc3ccc(F)cc3)ncnc21 CHEMBL1591510 Potency 5.0 nM
Cc1cc(C)c2c(=O)cc(C(F)(F)F)oc2n1 CHEMBL1607411 Potency 5.0 nM
CCOCCCNCc1ccc(OCC(=O)N2CCOCC2)c(OC)c1 CHEMBL1585727 Potency 5.0 nM
COc1ccc(NC(S)=NNC(=O)CCn2cc([N+](=O)[O-])cn2)cc1 CHEMBL1429384 Potency 5.0 nM
Cn1c(SCc2ccc(Cl)cc2)nc(C(F)(F)F)cc1=O CHEMBL1391202 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccc(F)cc2)n(CCC(=O)NCc2ccc(C)cc2)c1C CHEMBL1495850 Potency 5.0 nM
CC(C)n1c(O)c(N=NC(=O)C2COc3ccccc3O2)c2ccccc21 CHEMBL1574432 Potency 5.0 nM
Oc1c2ccccc2c2c3c(cccc13)N=N2 CHEMBL1725279 Potency 5.0 nM
Cc1ccc(CNC(=O)CN2C(=O)C3CCCCN3c3ccc(C(=O)N(C)C)cc32)cc1 CHEMBL1358455 Potency 5.0 nM
COc1cccc(Nc2nc3ccccc3n2C(C)C)c1 CHEMBL1378085 Potency 5.0 nM
O=C(CSCC(=O)NC1CCCC1)Nc1ccccc1 CHEMBL1495896 Potency 5.0 nM
COc1ccccc1C(=O)C1CCCN(C(=O)c2cc(C(C)C)no2)C1 CHEMBL1507217 Potency 5.0 nM
CC(C)(C)N=C(S)N=C(N)N[N+](=O)[O-] CHEMBL1349431 Potency 5.0 nM
COc1ccc(N(CC(=O)NCCC2=CCCCC2)S(=O)(=O)c2ccccc2)cc1OC CHEMBL1332396 Potency 5.0 nM
CCCCCn1c(=O)c2c(nc3n2CCN3c2ccc(Br)cc2)n(C)c1=O CHEMBL1445117 Potency 5.0 nM
c1ccc(-c2ccccn2)nc1 CHEMBL39879 Potency 5.0 nM
Cn1cc(CNCc2ccc(-n3cccn3)cc2)c(-c2ccccc2F)n1 CHEMBL1485602 Potency 5.0 nM
CCOc1ccc(C(CC(=O)O)NC(=O)C23CC4CC(CC(C4)C2)C3)cc1OC CHEMBL1407326 Potency 5.0 nM
Cc1ccc(NC(=O)CC2Sc3ccc(C(F)(F)F)cc3NC2=O)cc1 CHEMBL1612883 Potency 5.0 nM
CC(C)CNC(=O)Nc1ccccc1F CHEMBL1456678 Potency 5.0 nM
CCOc1ccc(C(=O)NC(=S)Nc2ccccc2N2CCOCC2)cc1Br CHEMBL1535379 Potency 5.0 nM
Cc1ccc(OCC(=O)Nc2ccc3c(c2)OCO3)c(C)c1 CHEMBL1485052 Potency 5.0 nM
O=C(NN1C(=O)c2ccccc2C1=O)c1ccncc1 CHEMBL450516 Potency 5.0 nM
CCCCc1nn2c(=O)cc(COC(=O)c3ccccc3C)nc2s1 CHEMBL1512145 Potency 5.0 nM
CCOc1ccc(-c2c(C)nn3c(C)c(C(=O)NCCN(C)C)cnc23)cc1OCC CHEMBL1437355 Potency 5.0 nM
Cc1cc(C)cc(NC(=O)c2cc(CN3CCCC3)on2)c1 CHEMBL1437449 Potency 5.0 nM
COc1ccc(N2CC(NC(=O)Cc3cccs3)CC2=O)cc1 CHEMBL1314426 Potency 5.0 nM
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@H](CCC(=O)O)C(=O)O)cc1 CHEMBL156 Potency 5.0 nM
O=C1NS(=O)(=O)c2ccccc21 CHEMBL310671 Potency 5.6 nM
CC(NCC#Cc1ccccc1)C(O)c1ccccc1 CHEMBL1488936 Potency 5.6 nM
COc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)s1 CHEMBL1331882 Potency 5.6 nM
COc1ccc(N2CC(C(=O)OCC(=O)c3ccc(C)cc3)CC2=O)cc1 CHEMBL1595396 Potency 5.6 nM
O=C1CC(c2ccccc2)CN1C(=O)c1cccnc1 CHEMBL1460139 Potency 5.6 nM
CC(N)=O CHEMBL16081 Potency 5.6 nM
O=C(NCc1ccccn1)c1ccccc1-c1ccccc1 CHEMBL1578846 Potency 5.6 nM
Cc1cccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)c1 CHEMBL1315714 Potency 5.6 nM
COc1ccc(NC(=O)C(c2ccccc2)N(C)C(=O)c2ccc(O)nc2)cc1 CHEMBL1582149 Potency 5.6 nM
CCOC(=O)N1CCC(=NNc2ccc(S(N)(=O)=O)cc2[N+](=O)[O-])CC1 CHEMBL1427205 Potency 5.6 nM
O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(O)cc2)N1c1ccc(F)cc1 CHEMBL1455301 Potency 5.6 nM
Cc1ccc(-n2cnc3cc(C(=O)NCc4ccccc4Cl)ccc32)c(C)c1 CHEMBL1434884 Potency 5.6 nM
CCOc1ccccc1N1C(=O)NC(=O)/C(=C\NCc2ccc3c(c2)OCO3)C1=O CHEMBL1465876 Potency 5.6 nM
O=C1Nc2ccccc2/N=C(/c2ccccc2)c2ccccc21 CHEMBL1346991 Potency 5.6 nM
O=C1CC[C@@H](C(=O)O)N1 CHEMBL397976 Potency 5.6 nM
Cc1ccc(OCC(O)C(C)NC(C)C)c2c1CCC2 CHEMBL1256784 Potency 5.6 nM
Cn1c(S)nnc1CNC(=O)OC(C)(C)C CHEMBL1455527 Potency 5.6 nM
CCCC(C)(COC(N)=O)COC(=O)NC(C)C CHEMBL1233 Potency 5.6 nM
Clc1cccc(Cl)c1NC1=NCCN1 CHEMBL1705 Potency 5.6 nM
Cc1snc(S(=O)(=O)Cc2ccccc2Cl)c1C#N CHEMBL1490999 Potency 5.6 nM
Cc1cc(C)c(NC(=O)C[C@H](CC(=O)[O-])c2cccc3ccccc23)c(C(=O)N2CCC3(CCCC3)CC2)c1 CHEMBL1335406 Potency 5.6 nM
CN(C)CC/C=C1\c2ccccc2COc2ccc(CC(=O)O)cc21 CHEMBL65699 Potency 5.6 nM
CCOC(=O)CCC(=O)N1CCOCCN(C(=O)CCC(=O)OCC)CCOCC1 CHEMBL1532542 Potency 5.6 nM
COc1ccc(C)cc1NC(=O)CNC(=O)Cn1ccc2ccccc2c1=O CHEMBL1610262 Potency 5.6 nM
CCN(CCn1cccn1)C(=O)c1cc(COc2c(F)cccc2F)on1 CHEMBL1597256 Potency 5.6 nM
O=S(=O)(Cc1cc(-c2ccccc2)no1)c1ccccc1 CHEMBL1580743 Potency 5.6 nM
CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 CHEMBL541268 Potency 5.6 nM
O=C(/C=C/c1cccc([N+](=O)[O-])c1)NC(=S)Nc1cccc(NC(=O)c2ccccc2)c1 CHEMBL1422301 Potency 5.6 nM
COc1ccc(Nc2oc(-c3ccc(COc4ccc(OC)cc4)o3)nc2C#N)cc1 CHEMBL1357268 Potency 5.6 nM
CCC1OC(=O)C(C)[C@@H](O[C@H]2C[C@@](C)(OC)C(O)C(C)O2)C(C)[C@@H](O[C@@H]2OC(C)CC(N(C)C)C2O)[C@@](C)(O)CC(C)C(=O)[C@@H](C)C(O)[C@]1(C)O CHEMBL1315430 Potency 5.6 nM
O=C(O)CCN(Cc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1F CHEMBL1530619 Potency 5.6 nM
CC1(C)SC2C(N3C(=O)C(c4ccccc4)NC3(C)C)C(=O)N2C1C(=O)[O-] CHEMBL1597993 Potency 5.6 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]2O[C@H](n3cnc4c(N)ncnc43)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O CHEMBL1610462 Potency 5.6 nM
Cc1cc(O)c2c(c1)C(=O)c1cc(O)cc(O)c1C2=O CHEMBL289277 Potency 5.6 nM
CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc([S+](C)[O-])cc1 CHEMBL15770 Potency 5.6 nM
CCOC(=O)c1ccc2nc(C)c(CCC(C)=O)c(O)c2c1 CHEMBL1492271 Potency 5.6 nM
O=C(COc1ccc(Cl)cc1)NCCc1csc(-c2ccc(F)cc2)n1 CHEMBL1398442 Potency 5.6 nM
CC(C)Cc1ccc(C(C)C(=O)O)cc1 CHEMBL521 Potency 5.6 nM
CCc1cccc(N(C)C(=N)Nc2cccc3ccccc23)c1 CHEMBL554054 Potency 5.6 nM
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 CHEMBL65 Potency 5.6 nM
Cc1ccccc1OCC(=O)NNC(=S)NC(=O)c1ccco1 CHEMBL1430574 Potency 5.6 nM
COc1ccc2[nH]c3c(c2c1)CCNC3 CHEMBL266084 Potency 5.6 nM
O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1)N1CCN(c2cccc(Cl)c2)CC1 CHEMBL1367103 Potency 5.6 nM
O=C(COC(=O)c1cccc(C(F)(F)F)c1)NCc1ccccc1 CHEMBL1509573 Potency 5.6 nM
c1ccc2c(N3CCNCC3)cccc2c1 CHEMBL1256192 Potency 5.6 nM
CCC(C)NC(=O)c1ccc(-n2c(-c3ccccc3)cc3c2CCCC3)cc1 CHEMBL1605327 Potency 6.3 nM
CCCCN(CC)C(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1cccc(Cl)c1 CHEMBL1354937 Potency 6.3 nM
C=CCc1ccccc1OCC(O)CNC(C)C CHEMBL1256179 Potency 6.3 nM
COC(=O)C1=C(C(=O)OC)[C@@H]2N(Cc3ccccc3)c3ccccc3[C@@]23C[C@@H](C(=O)OC)N(S(=O)(=O)c2ccc(Br)cc2)C3=N1 CHEMBL1592543 Potency 6.3 nM
CCOC(=O)c1ccc(-c2cc(C)no2)[nH]1 CHEMBL1499833 Potency 6.3 nM
COc1ccc(N(Cc2cccs2)C(=O)COc2cccc(C)c2C)cc1 CHEMBL1314781 Potency 6.3 nM
N#Cc1ccc2c(c1)N(CCCN1CCC(O)CC1)c1ccccc1S2 CHEMBL251940 Potency 6.3 nM
Cc1ccc(NC(=O)N2CCC(NC(=O)C(C)(C)C)CC2)cc1 CHEMBL1567644 Potency 6.3 nM
CCCCC[C@H](O)/C=C\[C@@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O CHEMBL1318789 Potency 6.3 nM
CN(C)/N=N\c1[nH]cnc1C(N)=O CHEMBL1355683 Potency 6.3 nM
O=C(O)CSCC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1 CHEMBL1611256 Potency 6.3 nM
O=[N+]([O-])c1ccc(S(=O)(=O)N2CCSC2c2ccco2)cc1 CHEMBL1455481 Potency 6.3 nM
CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@@H]2SC1 CHEMBL1314545 Potency 6.3 nM
O=C(OOC(=O)c1ccccc1)c1ccccc1 CHEMBL1200370 Potency 6.3 nM
CCCCCCN1CCN(c2ccccc2Cl)CC1 CHEMBL1578784 Potency 6.3 nM
CCOc1ccc(S(=O)(=O)Nc2cccc(-c3ccc(OCC)nn3)c2)cc1 CHEMBL1593066 Potency 6.3 nM
O=C(O)CCCCCCC1C(=O)NC(=O)N1CCC(O)C1CCCCC1 CHEMBL575504 Potency 6.3 nM
Cc1cc(C)c2oc(C(=O)Nc3nnc(C(C)C)s3)cc(=O)c2c1 CHEMBL1520669 Potency 6.3 nM
COc1ccc(CN2C(=O)c3ccccc3C2C(=O)NC2CCCC(C)C2C)c(OC)c1 CHEMBL1461136 Potency 6.3 nM
NC(CP(=O)(O)O)C(=O)O CHEMBL88621 Potency 6.3 nM
CCCCC(=O)N(CCOC)c1nnc(-c2ccccc2C)s1 CHEMBL1305257 Potency 6.3 nM
Cn1cnc(S(=O)(=O)N2CCC(C(=O)N3CCN(c4ccccc4F)CC3)CC2)c1 CHEMBL1515134 Potency 6.3 nM
CCOC(=O)c1cnc2c(-c3ccc(Cl)cc3)cnn2c1C CHEMBL1331001 Potency 6.3 nM
NCCNC(=O)c1ncsc1-c1cccc(F)c1 CHEMBL1256290 Potency 6.3 nM
CCN1C(=O)N[C@@H](c2ccco2)C(C(=O)OC)=C1C CHEMBL1332995 Potency 6.3 nM
Cc1ccc(CNC(=O)c2c(C)oc3nc(C)nc(N4CCOCC4)c23)cc1 CHEMBL1574257 Potency 6.3 nM
COC(=O)C1=C(C)N(Cc2ccccc2)C(=O)N[C@H]1c1ccccc1 CHEMBL1406573 Potency 6.3 nM
COc1ccc(C2C(C(=O)Nc3ccccc3)=C(C)Nc3nc(CCCO)nn32)cc1 CHEMBL1419296 Potency 7.1 nM
COc1cc2c3cc1Oc1cc(ccc1O)C[C@@H]1c4c(cc(OC)c(O)c4Oc4cccc(c4)C[C@H]3N(C)CC2)CC[N+]1(C)C CHEMBL1319771 Potency 7.1 nM
COc1ccc(CNC(=O)CSc2nnnn2Cc2ccccc2)cc1 CHEMBL1370618 Potency 7.1 nM
Cn1c(=O)c2c(ncn2C[C@@H](O)CO)n(C)c1=O CHEMBL1488819 Potency 7.1 nM
CCCCn1c(S)nnc1-c1ccco1 CHEMBL1301497 Potency 7.1 nM
Cc1cc(NC(=O)CSc2nccn2-c2cccc(C)c2C)no1 CHEMBL1331219 Potency 7.1 nM
COC(=O)c1ccccc1NC(=O)COc1ccc(S(=O)(=O)NC(C)C)cc1 CHEMBL1411583 Potency 7.1 nM
COC/C=C/C1=CC2=CC(=O)C(C)(OC(=O)c3cnc4ccccc4n3)C(=O)C2=CN1C(CO)CO CHEMBL1565367 Potency 7.1 nM
CC(=O)N1CCCc2ccc(NC(=O)c3ccc(OC(C)C)cc3)cc21 CHEMBL1436104 Potency 7.1 nM
CC(C)OCCCNC(=O)C(NC(=O)c1ccc(Cl)cc1)C(C)C CHEMBL1460066 Potency 7.1 nM
C=C(C)CNC(=S)N/N=C\c1ccc2c(c1)OCO2 CHEMBL1989706 Potency 7.1 nM
CCN(CC)CCNC(=O)c1cc(S(C)(=O)=O)ccc1OC CHEMBL84158 Potency 7.1 nM
CN(C)c1ccc(N/C=C/C(=O)C(F)(F)F)cc1 CHEMBL1594507 Potency 7.1 nM
Cc1cccnc1NC(=O)C1c2ccccc2Oc2ccccc21 CHEMBL1461517 Potency 7.1 nM
CCCCS(=O)(=O)/C=C\C1C2C=CC(C2)C1S(=O)(=O)CCCC CHEMBL1362773 Potency 7.1 nM
C=Cn1ccnc1P(=S)(c1c(C)nn(-c2ccccc2)c1C)c1nccn1C=C CHEMBL1384723 Potency 7.1 nM
O=C(CSc1nc2ccccc2c2nc(-c3ccccc3)nn12)Nc1ccc(Br)cc1 CHEMBL1560183 Potency 7.1 nM
CCOC(=O)C1=C(Nc2ccc(C)cc2)SCC1=O CHEMBL1336364 Potency 7.1 nM
CCc1ccc(C(C(=O)NC2CCCC2)N(C(=O)/C=C/C(=O)Nc2cc(C)on2)c2ccccc2C)cc1 CHEMBL1572423 Potency 7.1 nM
O=C(Cc1ccc(-c2ccccc2)cc1)NCCS(=O)(=O)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1443145 Potency 7.1 nM
COc1ccc(Nc2cc(C)c3ccccc3n2)cc1 CHEMBL1364400 Potency 7.1 nM
CCc1ccc(C2=NN(CCC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)CC2)cc1 CHEMBL1534822 Potency 7.1 nM
Cn1nnnc1SCCNCc1ccc(F)cc1 CHEMBL1561048 Potency 7.1 nM
CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1 CHEMBL1086 Potency 7.1 nM
CCOc1cccc2cc(-c3nc(-c4ccc(Cl)cc4)c(C)s3)c(=O)oc12 CHEMBL1566164 Potency 7.1 nM
COc1ccc(NC(=O)C2(c3cccs3)CCOCC2)cc1Cl CHEMBL1440272 Potency 7.1 nM
CCOc1ccccc1C(=O)N1CCC(c2nc3ccccc3o2)CC1 CHEMBL1315187 Potency 7.1 nM
Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)N4CCCc5ccccc54)c32)cc1 CHEMBL1590735 Potency 7.1 nM
CNCCCC1c2ccccc2C=Cc2ccccc21 CHEMBL668 Potency 7.1 nM
COc1ccc(C(=O)Nc2ccc(S(=O)(=O)N(Cc3ccccc3)c3ccccc3)cc2)cc1 CHEMBL1473750 Potency 7.1 nM
O=C(NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL1451203 Potency 7.1 nM
Cc1cc(C)c(C(=O)Nc2ccc(Br)c(C(F)(F)F)c2)c(C)c1 CHEMBL1312122 Potency 7.1 nM
Cc1cn2c(=O)cc(COC(=O)c3ccc(NC(=O)c4ccc(C(C)(C)C)cc4)cc3)nc2s1 CHEMBL1555145 Potency 7.1 nM
CN(C)c1nc(N(C)C)n(C(=O)c2cccs2)n1 CHEMBL1352841 Potency 7.1 nM
COc1cc(C(C)=O)cc(OC)c1O CHEMBL224146 Potency 7.1 nM
CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC CHEMBL86 Potency 7.1 nM
CC(C)COC[C@H](CN(Cc1ccccc1)c1ccccc1)N1CCCC1 CHEMBL251075 Potency 7.1 nM
O=C(CCCn1c(SCC(=O)NCCc2ccccc2)nc2ccccc2c1=O)NCC1CCCO1 CHEMBL1471500 Potency 7.1 nM
COc1ccccc1N1CCN(C(=O)CCc2c[nH]c3ccccc23)CC1 CHEMBL1588898 Potency 7.1 nM
C=C(C)C1Cc2cc3ccc(=O)oc3cc2O1 CHEMBL1467672 Potency 7.1 nM
CN1CCc2nc(SCC(=O)Nc3ccc(OC(F)(F)F)cc3)c(C#N)c(-c3cccs3)c2C1 CHEMBL1574609 Potency 7.1 nM
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)CC2)c(C)c1 CHEMBL1338855 Potency 7.1 nM
CCOC(=O)CCc1nc2ccccc2nc1O CHEMBL1373150 Potency 7.1 nM
C(Cc1nn[nH]n1)Cc1nn[nH]n1 CHEMBL1477631 Potency 7.9 nM
CN(C)CC1CSCCC1(O)c1ccc(C(F)(F)F)cc1 CHEMBL1329736 Potency 7.9 nM
CC(C)N1CCN(c2ccc(OC[C@@H]3CO[C@@](Cn4cncn4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 CHEMBL1410669 Potency 7.9 nM
CS/C(=C\[N+](=O)[O-])Nc1ccc(OC(F)(F)F)cc1 CHEMBL1567419 Potency 7.9 nM
COc1cc(C(=O)NCC(c2cccnc2)N2CCc3ccccc3C2)cc(OC)c1OC CHEMBL1529082 Potency 7.9 nM
CCCCOc1ccc(CNC(=O)CN2C(=O)CCn3nc(-c4cn(C)c5ccccc45)cc32)cc1 CHEMBL1450435 Potency 7.9 nM
COCCN(C(=O)CSc1nnc(C)n1-c1ccccc1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O CHEMBL1490669 Potency 7.9 nM
C=CCc1cc(Cl)ccc1OCCOCCN(C)C CHEMBL1381276 Potency 7.9 nM
c1nc(NC2CCCC2)c2nc[nH]c2n1 CHEMBL271139 Potency 7.9 nM
O=C(NC(=S)NCC1CCCO1)c1cccc([N+](=O)[O-])c1 CHEMBL1526892 Potency 7.9 nM
N#Cc1ccc(C(=O)NCC(c2ccco2)N2CCCC2)cc1 CHEMBL1424193 Potency 7.9 nM
O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1ccc(NC(=O)C(F)(F)F)cc1 CHEMBL1533100 Potency 7.9 nM
COc1ccc(OC)c(CNc2ncnc3onc(C)c23)c1 CHEMBL1363584 Potency 7.9 nM
CC1CCN(C(=O)Cn2c(=O)n(CC3CCC(C(=O)NC(C)C)CC3)c(=O)c3sccc32)CC1 CHEMBL1474007 Potency 7.9 nM
CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O CHEMBL1084643 Potency 7.9 nM
O=S(=O)(c1cc(Cl)ccc1Cl)n1ccnc1 CHEMBL1560591 Potency 7.9 nM
CSc1ncnc2sc(C)c(C)c12 CHEMBL1572620 Potency 7.9 nM
CCOc1cc(C2C(C(=O)OC)=C(C)NC3=C2C(=O)c2ccccc23)c(Br)cc1O CHEMBL1395816 Potency 7.9 nM
CCc1ccccc1NC(=O)c1cc(S(=O)(=O)N2CCC(C)CC2)cn1C CHEMBL1612339 Potency 7.9 nM
Cc1ccc(NC(=O)COC(=O)CCc2nc(O)c3ccccc3n2)c(Br)c1 CHEMBL1599760 Potency 7.9 nM
COc1ccc(S(=O)(=O)Nc2ccc(-c3ccc(N4CCCC4)nn3)cc2)cc1F CHEMBL1395643 Potency 7.9 nM
Cc1ccc(C(=O)COC(=O)CNC(=O)CNC(=O)c2ccc(C)cc2)cc1 CHEMBL1519932 Potency 7.9 nM
O=C(NCc1cccs1)c1cnc2ccccn2c1=O CHEMBL1463313 Potency 7.9 nM
COc1ccc(OC)c(NC(=O)CCn2cccn2)c1 CHEMBL1434485 Potency 7.9 nM
Cc1[nH]ccc2c1[nH]c1cc(=O)ccc12 CHEMBL486817 Potency 7.9 nM
O=C(Nc1nc(-c2cccs2)c(C(=O)C(F)(F)F)s1)c1ccco1 CHEMBL1409901 Potency 7.9 nM
CSc1nc(-c2ccccc2)c(C#N)c(=O)n1C CHEMBL1413021 Potency 7.9 nM
Cc1cc([N+](=O)[O-])ccc1NC(=O)c1cccc(NC(=O)C(C)C)c1 CHEMBL1374512 Potency 7.9 nM
CCN(CC)C(=O)c1sc2c(c1C)c(=O)n(-c1ccc(Cl)c(Cl)c1)c(=O)n2Cc1cc(=O)n2ccccc2n1 CHEMBL1570596 Potency 7.9 nM
Cc1nnc(SC(C(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)c2ccccc2)nc1O CHEMBL1541483 Potency 7.9 nM
Cc1cc(C)cc(NC(S)=NC2CC3CCCC(C2)N3CC(C)C)c1 CHEMBL1424246 Potency 7.9 nM
NCCCC(=O)O CHEMBL96 Potency 7.9 nM
Cn1cc(S(=O)(=O)N2CCCC2)cc1C(=O)Nc1ccc(C(F)(F)F)cc1 CHEMBL1417934 Potency 7.9 nM
Cc1ccccc1CS(=O)(=O)c1cn(CC(=O)N2CCC(C)CC2)c2ccccc12 CHEMBL1311892 Potency 7.9 nM
CC1=C(c2ccc(Cl)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccccc2F)CC1 CHEMBL1476835 Potency 7.9 nM
Sc1nnc(-c2ccc(Br)cc2)n1Cc1ccccc1 CHEMBL1368075 Potency 7.9 nM
c1ccc(-n2cc(CN3CCCC(CN4CCCC4)C3)c(-c3ccc4c(c3)OCO4)n2)cc1 CHEMBL1564448 Potency 7.9 nM
O=C(NC1CC(=O)N(c2ccccc2)C1)c1ccc(S(=O)(=O)N2CCCCC2)cc1 CHEMBL1564406 Potency 7.9 nM
O=C(/C=C/c1ccco1)NCc1ccc(F)cc1 CHEMBL1549915 Potency 7.9 nM
CSc1nc(-c2ccco2)nn1C(=O)c1ccccc1 CHEMBL490107 Potency 7.9 nM
O=C(c1ccccc1)N1CCN(C(=S)NCc2ccc3c(c2)OCO3)CC1 CHEMBL1589265 Potency 7.9 nM
CCOc1ccc(Br)cc1S(=O)(=O)N1CCC(C(=O)O)CC1 CHEMBL1368689 Potency 7.9 nM
CC(=O)N1N=C(c2ccc(C)cc2)CC1c1ccco1 CHEMBL1607720 Potency 7.9 nM
Cc1ccc(-c2nc3scc(CCNC(=O)c4cccc(Br)c4)n3n2)cc1 CHEMBL1327196 Potency 7.9 nM
C#CCN1C(=O)C(O)(CC(=O)/C=C/c2ccco2)c2ccccc21 CHEMBL1427654 Potency 7.9 nM
O=S1(=O)c2ccccc2N(Cc2cccc(Cl)c2)c2ccccc21 CHEMBL1496489 Potency 7.9 nM
CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL1170 Potency 7.9 nM
O=C(OCC(=O)N1CCc2ccccc2C1)c1cccnc1Cl CHEMBL1507903 Potency 7.9 nM
C#CCOC(=O)C1=CCCN(C)C1 CHEMBL1255649 Potency 7.9 nM
CC(C)C(=O)Nc1cccc(C(=O)Nc2nncs2)c1 CHEMBL1563816 Potency 7.9 nM
O=[N+]([O-])c1ccccc1S(=O)(=O)NCc1ccc(F)cc1 CHEMBL1612721 Potency 7.9 nM
CCOc1ccccc1NC(=O)C1=C(C)Nc2ncnn2C1c1sccc1C CHEMBL1394101 Potency 7.9 nM
O=C(CCl)Nc1ccccc1C(=O)NCc1ccccc1 CHEMBL1600963 Potency 7.9 nM
CCOc1ccc(CN2CCN(C/C=C/c3ccc(OC)cc3)CC2CCO)cc1 CHEMBL1309340 Potency 7.9 nM
CCCCN(CC)C(S)=Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 CHEMBL1547524 Potency 7.9 nM
CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(-c3ccc(N4CCCCCC4)nn3)c2)cc1 CHEMBL1407248 Potency 7.9 nM
COc1ccc(-c2nnc(SCC(=O)Nc3cc(C)on3)o2)cc1 CHEMBL1470284 Potency 7.9 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccc(C)cc2)CC1 CHEMBL1551510 Potency 8.9 nM
COc1ccc(Cl)cc1CNCCSc1nnnn1-c1ccccc1 CHEMBL1433947 Potency 8.9 nM
CCCNc1nc(N2CCCC2)nc(N2CCCC2)n1 CHEMBL1477710 Potency 8.9 nM
Cn1cc(CNCc2c[nH]nc2-c2ccc(F)cc2)c(-c2ccc3c(c2)OCCO3)n1 CHEMBL1537178 Potency 8.9 nM
N=C(N)NC(=O)c1nc(Cl)c(N)nc1N CHEMBL540851 Potency 8.9 nM
CC(C)(C)C(=O)OC1=CN(Cc2ccccc2)S(=O)(=O)c2ccccc21 CHEMBL1434112 Potency 8.9 nM
CCOc1cc(C(N)=O)cc(Cl)c1OCC CHEMBL1528935 Potency 8.9 nM
Cc1c(C(c2ccccc2O)c2c(C)n(C)n(-c3ccccc3)c2=O)c(=O)n(-c2ccccc2)n1C CHEMBL1538947 Potency 8.9 nM
Cc1ccc(NC(=O)COC(=O)C2CC2C)c(S(=O)(=O)N2CCCCC2)c1 CHEMBL1595489 Potency 8.9 nM
COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1[C@@H](NC(C)=O)CC2 CHEMBL107 Potency 8.9 nM
COCCN(Cc1cc2cc(C)ccc2n2nnnc12)C(S)=Nc1cccc(C)c1 CHEMBL1329262 Potency 8.9 nM
C=CCN1/C(=C\CO)[C@H]2C[C@@H]3[C@@H]1CC[C@]31c3ccccc3N3/C=C4\[C@@H]5N(/C=C\2[C@H]31)c1ccccc1[C@@]51CC[C@H]2[C@@H]1C[C@@H]4/C(=C\CO)N2CC=C CHEMBL1555513 Potency 8.9 nM
Cc1c(Br)c([N+](=O)[O-])nn1CC(=O)Nc1ccc(C(C)C)cc1 CHEMBL1517732 Potency 8.9 nM
O=C(CSc1nnc(C2CC2)n1Cc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1 CHEMBL1372089 Potency 8.9 nM
COc1ccc(-c2nc3sc(CCNS(=O)(=O)c4ccccc4)c(C)n3n2)cc1 CHEMBL1475425 Potency 8.9 nM
CCOC(=O)C1=C(C)N(CCO)C(=O)NC1c1ccccc1 CHEMBL1577619 Potency 8.9 nM
CC(=O)N(CCC1(C(C)C)CCOC(C)(C)C1)Cc1ccco1 CHEMBL1538990 Potency 8.9 nM
O=C(c1ccc(Br)cc1)N(Cc1ccco1)c1ccccn1 CHEMBL1565389 Potency 8.9 nM
Cc1ccc(Cl)cc1-n1ncc2c(NC3CCCCC3)ncnc21 CHEMBL1472945 Potency 8.9 nM
CC(C)(C)NS(=O)(=O)c1cccc(S(=O)(=O)c2cccc(S(=O)(=O)NC(C)(C)C)c2)c1 CHEMBL1555674 Potency 8.9 nM
CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O CHEMBL7763 Potency 8.9 nM
O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1ccc(N2C(=O)c3ccccc3C2=O)cc1 CHEMBL1363689 Potency 8.9 nM
C/C(=N\OCC(=O)Nc1ccccc1Br)c1cccs1 CHEMBL3195626 Potency 8.9 nM
COc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N(C)c2ccc(Cl)cc2)s1 CHEMBL1355675 Potency 8.9 nM
COc1ccc(C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1OC CHEMBL1385991 Potency 8.9 nM
C/C(=N\NS(=O)(=O)c1ccccc1)c1ccc2c(c1)OCO2 CHEMBL3209588 Potency 8.9 nM
CCNC(=O)CC1C(=O)N(c2ccc(C)cc2)C(=O)N1CCc1sccc1C CHEMBL1572467 Potency 8.9 nM
Cc1ccc(NC(=O)COC(=O)c2cc(-c3cccs3)nn2-c2ccccc2)cc1[N+](=O)[O-] CHEMBL1306172 Potency 8.9 nM
CCCCc1nn2c(=O)cc(COC(=O)c3cccs3)nc2s1 CHEMBL1336435 Potency 8.9 nM
CC(=O)Nc1ccc2nc(NC(=O)COc3cccc(C)c3)sc2c1 CHEMBL1572407 Potency 8.9 nM
O=C(/C=C/c1ccccc1)NCC(=O)N/N=C\c1cccnc1 CHEMBL3214617 Potency 8.9 nM
CC(=O)N1CCc2cc(S(=O)(=O)CCC(=O)NCc3ccc(Cl)cc3)ccc21 CHEMBL1606584 Potency 8.9 nM
COc1cccc(N2C(=O)NC(=O)/C(=C\c3ccc([N+](=O)[O-])s3)C2=O)c1 CHEMBL1442893 Potency 8.9 nM
CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)cc1 CHEMBL1410 Potency 8.9 nM
C=Cn1ccnc1P(=S)(c1nccn1C=C)c1nccn1C=C CHEMBL1346386 Potency 8.9 nM
O=C(OCC1CC(c2ccccc2)=NO1)c1ccc(Br)cc1 CHEMBL1376490 Potency 8.9 nM
COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(c3c(Cc4ccccc4)c(C)nc4ncnn34)CC2)cc1OC CHEMBL1572529 Potency 8.9 nM
COc1cc(-c2nc3ccccc3c(=O)n2N)cc(OC)c1OC CHEMBL1560789 Potency 8.9 nM
Cc1nc(OCc2c(C)noc2C)c2ccccc2n1 CHEMBL1346809 Potency 8.9 nM
C/C(=N\NC(=O)CNc1cccc(Cl)c1C)C1CC1 CHEMBL3212733 Potency 8.9 nM
Cc1ccc(NC(=O)CCn2ccc([N+](=O)[O-])n2)nc1 CHEMBL1387853 Potency 8.9 nM
CCCN1CC[C@@H]2c3cc(O)ccc3CC[C@@H]21 CHEMBL1256854 Potency 8.9 nM
COc1ccc(CC(=O)N2CCC(c3ccccc3)C2)cc1 CHEMBL1324974 Potency 8.9 nM
Cc1cc(C)c(Nc2ncccc2C(=O)O)c(C)c1 CHEMBL1451554 Potency 8.9 nM
O=C(NNC(=O)C1CC1c1ccccc1)Nc1cccc(Cl)c1 CHEMBL1500893 Potency 8.9 nM
CCOC(=O)c1ccc(NC(=O)CC2SCCNC2=O)cc1 CHEMBL1373823 Potency 8.9 nM
Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL91 Potency 8.9 nM
CCc1cc2cc(C)cc(C)c2nc1SCC(=O)Nc1cc(C)on1 CHEMBL1344061 Potency 8.9 nM
O=C(NC(=S)Nc1nc2ccccc2s1)c1cccs1 CHEMBL1095276 Potency 8.9 nM
Cc1ccc(NC(=O)N(Cc2ccc3c(c2)OCO3)Cc2cc3cc4c(cc3nc2O)OCCO4)cc1 CHEMBL1402215 Potency 8.9 nM
Cc1c(Cl)cccc1NC(=O)Nc1cc(C(C)(C)C)nn1C CHEMBL1540816 Potency 8.9 nM
O=C(Nc1ccc(N2CCCC2)c(Cl)c1)c1cccc(-c2cc3ccccc3oc2=O)c1 CHEMBL1598118 Potency 8.9 nM
CCCn1nc(C(=O)OCC(=O)Nc2cccc(OC)c2)c2ccccc2c1=O CHEMBL1479493 Potency 8.9 nM
O=C(O)/C=C\c1ccc(Cn2ccnc2)cc1 CHEMBL1317458 Potency 8.9 nM
O=C(c1ccco1)N(Cc1cccnc1)c1nc2ccc(F)cc2s1 CHEMBL589729 Potency 8.9 nM
Clc1ccc(C2NCCc3[nH]cnc32)cc1 CHEMBL1334934 Potency 8.9 nM
Cc1nnc(SCC(=O)Nc2ccc3c(c2)OCO3)nc1O CHEMBL1578417 Potency 8.9 nM
O=C(Nc1cccc(F)c1)Nc1ccccn1 CHEMBL1383401 Potency 8.9 nM
OC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 CHEMBL445102 Potency 8.9 nM
CC(=O)Nc1sc2c(c1C(c1ccncc1)N1CCOCC1)CCCC2 CHEMBL1527453 Potency 8.9 nM
CCn1c(C)c(/C=N/Nc2nc3ccccc3s2)c2ccccc21 CHEMBL3210057 Potency 8.9 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2)cc1 CHEMBL273264 Potency 8.9 nM
Cc1ccc(OCc2ccc(-c3nc(C#N)c(N4CCN(c5cccc(Cl)c5)CC4)o3)o2)cc1 CHEMBL1520673 Potency 8.9 nM
CC(C)C(=O)NCc1cc(-c2ccc(Cl)cc2)no1 CHEMBL1333532 Potency 8.9 nM
CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 CHEMBL1321983 Potency 8.9 nM
CCCn1nc(Oc2nc(NC(C)C)nc(N(C)C)n2)ccc1=O CHEMBL1370845 Potency 8.9 nM
O=C(/C=C/c1ccccc1Cl)Nn1cnc2ccccc2c1=O CHEMBL1343059 Potency 8.9 nM
Clc1ccc(CSc2nnc([C@@H]3CCCN3)o2)cc1 CHEMBL1402038 Potency 8.9 nM
Cc1cnc([N+](=O)[O-])n1CCOC(=O)NC(=O)c1ccc(C(F)(F)F)cc1 CHEMBL1344747 Potency 8.9 nM
COc1ccc(CCN2C(=O)c3cccc4c(C(=O)N5CCCCC5)ccc(c34)C2=O)cc1OC CHEMBL1581094 Potency 8.9 nM
COc1ccccc1CC(=N)NOC(=O)c1ccc2c(c1)OCO2 CHEMBL1519067 Potency 8.9 nM
CCSc1nc(-c2ccccc2)nc2c1CCCC2 CHEMBL1531726 Potency 8.9 nM
COc1ccc(C(=O)NCCc2cc3c(OC)ccc(OC)c3nc2O)cc1OC CHEMBL1344662 Potency 8.9 nM
CCC(COC(=O)c1cc(OC)c(OC)c(OC)c1)(c1ccccc1)N(C)C CHEMBL1325297 Potency 8.9 nM
O=C(COC(=O)C12CC3CC(CC(Br)(C3)C1)C2)Nc1cccnc1Cl CHEMBL1378213 Potency 8.9 nM
COC(=O)NN=C(S)Nc1ccccc1 CHEMBL1535472 Potency 8.9 nM
C[C@H]1O[C@H]1P(=O)([O-])[O-] CHEMBL2028172 Potency 8.9 nM
COc1cc(NCCC(=O)c2cccs2)c(OC)cc1Cl CHEMBL1486265 Potency 8.9 nM
COc1cc(N[C@@H](C)CCCN)c2ncccc2c1 CHEMBL249843 Potency 8.9 nM
Cn1c(=O)oc2cc(S(=O)(=O)CCC(=O)NCCc3ccccc3)ccc21 CHEMBL1413952 Potency 8.9 nM
COc1ccc(Cn2ccc3nc(C)c(C(=O)N4CCN(c5ccc(F)cc5)CC4)cc3c2=O)cc1 CHEMBL1396353 Potency 8.9 nM
O=C(CN1C(=O)NC2(CCCCCC2)C1=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 CHEMBL1511199 Potency 8.9 nM
Cc1nc(N)c(Br)c(C)c1Br CHEMBL1453014 Potency 8.9 nM
COc1cccc(NS(=O)(=O)c2ccc(S(=O)(=O)N3CCOCC3)cc2)c1 CHEMBL1589242 Potency 8.9 nM
C=C1NC(=O)c2cc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)ccc2N1 CHEMBL1366159 Potency 8.9 nM
CC(NC(=O)C1CC12CCC2)c1ccccc1 CHEMBL1445937 Potency 8.9 nM
CCCC[N+]1(C)[C@@H]2C[C@@H](OC(=O)[C@H](CO)c3ccccc3)C[C@H]1[C@@H]1O[C@@H]12 CHEMBL1256901 Potency 8.9 nM
Cc1cccc(-c2noc(CNC(=O)Nc3ccc(F)cc3)n2)c1 CHEMBL1348324 Potency 8.9 nM
COc1cccc(CNS(=O)(=O)c2ccc3c(c2)C(C(C)C)C(=O)N3)c1 CHEMBL1515844 Potency 8.9 nM
O=C(NC1CC(=O)N(c2cccc(F)c2)C1)c1cc2ccccc2o1 CHEMBL1316085 Potency 8.9 nM
CCc1ccccc1N(C(C)=O)c1nc(CCl)cs1 CHEMBL1430575 Potency 8.9 nM
FC(F)(F)c1ccc(Oc2ccc3c(C(F)(F)F)cc(C(F)(F)F)nc3n2)cc1 CHEMBL1457081 Potency 8.9 nM
Cc1nn(C)c2c1c(C(F)(F)F)cc(=O)n2C(C)C(=O)N1CCN(c2ccccc2)CC1 CHEMBL1444581 Potency 8.9 nM
O=C(CSc1nc2ccccc2c(=O)n1-c1ccccc1)NCc1ccco1 CHEMBL1378168 Potency 8.9 nM
Cc1ccc(N(CC(=O)NC(C)(C)C)C(=O)CNC(=O)c2cccs2)cc1C CHEMBL1547148 Potency 8.9 nM
Cc1ccc(Cn2c(=O)n(CC3CCC(C(=O)N4CCOCC4)CC3)c(=O)c3sccc32)cc1 CHEMBL1574194 Potency 8.9 nM
COc1cc(OC)c2c(C)c(Cl)c(=O)oc2c1 CHEMBL1388479 Potency 8.9 nM
CCN(CC)S(=O)(=O)c1ccc(NC(=O)COC(=O)CNS(=O)(=O)/C=C/c2ccccc2)cc1 CHEMBL1467829 Potency 8.9 nM
O=C(NCc1ccc(F)cc1)c1cc2cccc3c2n1CCS3 CHEMBL1553103 Potency 8.9 nM
O=C(COc1ccccc1)N1CCN(S(=O)(=O)Cc2ccccc2)CC1 CHEMBL1507213 Potency 8.9 nM
Cc1ccc(C(=O)NCC(=O)OC(C)C(=O)Nc2ccc(N(C)C)cc2)s1 CHEMBL1485140 Potency 8.9 nM
CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 CHEMBL22077 Potency 8.9 nM
CC1(C)S[C@@H]2[C@H](NC(=O)[C@@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O CHEMBL1367635 Potency 8.9 nM