O=C(O)c1cc(Cl)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL3322514 EC50 0.00506 nM
O=C(O)c1cc(F)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL3322513 EC50 0.15 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5sc(C)nc5C)cccc34)CC2)s1 CHEMBL5397550 pIC50 0.2512 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5cccc(CN6CCCC6)c5)cccc34)CC2)s1 CHEMBL5395244 pIC50 0.2818 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5cccc(CN(C)C)c5)cccc34)CC2)s1 CHEMBL5424571 pIC50 0.3311 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5cn(C)nc5C(F)(F)F)cccc34)CC2)s1 CHEMBL5424662 pIC50 0.3467 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5cccnc5C)cccc34)CC2)s1 CHEMBL5434096 pIC50 0.4467 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5ccc(CN6CCCC6)cc5)cccc34)CC2)s1 CHEMBL5427161 pIC50 0.5754 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5ccc(F)c(CN(C)C)c5)cccc34)CC2)s1 CHEMBL5405450 pIC50 0.6026 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5c(C)noc5C)cccc34)CC2)s1 CHEMBL5393777 pIC50 0.7586 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5cccnc5)cccc34)CC2)s1 CHEMBL5424251 pIC50 0.955 nM
Cc1[nH]nc(-c2ccc(OCc3nnn[nH]3)cc2O)c1Oc1ccc(Cl)cc1Cl CHEMBL5182278 Kd 1.3 nM
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O CHEMBL117021 EC50 2.0 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(-c5ccc(C)nc5)cccc34)CC2)s1 CHEMBL5418199 pIC50 2.455 nM
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)COP(=O)(O)O CHEMBL1222042 EC50 3.0 nM
Cc1noc(-c2ccc(S(=O)(=O)N3CCN(C[C@H](C)Nc4ncnc5c(C(F)(F)F)cccc45)CC3)s2)c1C CHEMBL5411589 pIC50 5.754 nM
CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1Cl CHEMBL119116 IC50 6.6 nM
O=C(O)/C=C/C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)/C=C/C(=O)O)cc3)c2)cc1 CHEMBL482498 Ki 7.2 nM
Cc1cccc(C2CC2C(=O)Nc2nc3ccccc3[nH]2)c1 CHEMBL5283300 IC50 10.0 nM
O=C(Nc1nc2cc(Cl)ccc2[nH]1)C1CC1c1ccccc1 CHEMBL5290275 IC50 10.0 nM
O=C(Nc1nc2ccccc2[nH]1)C1CC1c1ccccc1Cl CHEMBL5278054 IC50 10.0 nM
O=C(Nc1nc2cc(C(F)(F)F)ccc2[nH]1)C1CC1c1ccccc1 CHEMBL5266099 IC50 10.0 nM
CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1C CHEMBL119440 IC50 15.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(Cl)c4)CC3)ncnc12 CHEMBL256470 IC50 17.0 nM
CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL441826 IC50 18.0 nM
O=C(O)/C=C/C(=O)Nc1cccc(NC(=O)/C=C/C(=O)O)c1 CHEMBL519002 Ki 20.8 nM
O=C(O)/C=C/C(=O)Nc1ccc(-c2ccc(NC(=O)/C=C/C(=O)O)cc2)cc1 CHEMBL482497 Ki 21.1 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br CHEMBL332667 IC50 23.0 nM
CCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL119256 IC50 26.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)NCCOP(=O)(O)O CHEMBL117754 EC50 30.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C CHEMBL331054 IC50 32.0 nM
CCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL118783 IC50 33.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)ncnc12 CHEMBL270865 IC50 35.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Br CHEMBL119354 IC50 36.0 nM
CCCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL118860 IC50 40.0 nM
CCCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL118815 IC50 42.0 nM
Cc1noc(-c2ccc(S(=O)(=O)N3CCN(C[C@H](C)Nc4ncnc5c(C)csc45)CC3)s2)c1C CHEMBL5413416 pIC50 43.65 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C(F)(F)F)cccc34)CC2)s1 CHEMBL5399159 pIC50 44.67 nM
O=C(O)c1ccc(Br)cc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL3322507 EC50 50.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Cl CHEMBL119413 IC50 55.0 nM
CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117715 IC50 57.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1F CHEMBL119873 IC50 59.0 nM
O=C(O)c1cc(Br)ccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL3322508 EC50 60.0 nM
CCCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL333335 IC50 74.0 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117723 IC50 80.0 nM
CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL432813 IC50 89.0 nM
CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC CHEMBL2335052 EC50 100.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)NCCC(=O)P(O)(O)=S CHEMBL117798 EC50 108.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)NCCOP(O)(O)=S CHEMBL3621959 EC50 108.0 nM
CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC CHEMBL2335047 pEC50 109.65 nM
O=C(O)c1ccccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL3322502 EC50 110.0 nM
CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC CHEMBL357053 EC50 112.0 nM
CCCCCCCCCCCCCCCCOC(COC)COP([O-])(O)=S CHEMBL2335049 pEC50 114.82 nM
CCCCCCCCCCCCCCCCCOC(COC)COP([O-])(O)=S CHEMBL2335050 EC50 117.0 nM
CCCCCCc1ccc(-c2ccc(CNCCCP(=O)(O)O)cc2)cc1 CHEMBL116981 IC50 120.0 nM
CCCCCCCc1nc(-c2ccc(CNCCCP(=O)(O)O)cc2)no1 CHEMBL323617 IC50 120.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4cnc(-c5ccccc5)s4)CC3)ncnc12 CHEMBL5404276 pIC50 128.82 nM
COC(=O)c1cccc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(Cl)c4)CC3)ncnc12 CHEMBL5405375 pIC50 128.82 nM
CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP([O-])(O)=S CHEMBL2335051 EC50 146.0 nM
CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC CHEMBL153043 pEC50 147.91 nM
CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC CHEMBL2017139 EC50 161.0 nM
Cc1ccc(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C)csc34)CC2)cc1 CHEMBL401756 IC50 170.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)([O-])O CHEMBL3621353 Ki 170.0 nM
CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)([O-])O CHEMBL3621354 Ki 170.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4cc(Cl)c(Cl)s4)CC3)ncnc12 CHEMBL5406143 pIC50 239.88 nM
CCCCCCCC/C=C/CCCCCCCCOP(O)(O)=S CHEMBL187459 EC50 244.0 nM
CCCCCCCCC(=O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL115970 IC50 250.0 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C(=O)N(C)C)cccc34)CC2)s1 CHEMBL5405856 pIC50 257.04 nM
CCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL325247 IC50 260.0 nM
Cc1ccccc1N1CCN(C[C@H](C)Nc2ncnc3c(C)csc23)CC1 CHEMBL404452 IC50 260.0 nM
CCCCCCCn1nnc(-c2ccc(CNCCCP(=O)(O)O)cc2)n1 CHEMBL119382 IC50 270.0 nM
CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O CHEMBL364797 pEC50 288.4 nM
Cc1cccc(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C)csc34)CC2)c1 CHEMBL427893 IC50 310.0 nM
CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC CHEMBL2335048 EC50 350.0 nM
O=C(O)/C=C/C(=O)Nc1cccc(NC(=O)/C=C/C(=O)O)c1C(=O)O CHEMBL485119 IC50 355.0 nM
CCCC/C=C/CCCCCCCCOP(=O)(O)O CHEMBL190430 EC50 397.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1OCC CHEMBL324820 IC50 420.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1OC CHEMBL118508 IC50 450.0 nM
COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C)csc34)CC2)s1 CHEMBL5424552 pIC50 478.63 nM
CCCC/C=C/CCCCCCCCOP(O)(O)=S CHEMBL187402 EC50 480.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL332373 IC50 530.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(F)c(Cl)c4)CC3)ncnc12 CHEMBL5435934 pIC50 562.34 nM
CC/C=C/CCCCCCCCOP(O)(O)=S CHEMBL190484 EC50 677.0 nM
CCCCCCCOC(=O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL117403 IC50 700.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(C(F)(F)F)c4)CC3)ncnc12 CHEMBL5396575 pIC50 707.95 nM
CC/C=C/CCCCCCCCOP(=O)(O)O CHEMBL190349 EC50 717.0 nM
Cc1ccccc1N1CCN(C[C@H](C)Nc2nc(C(F)(F)F)nc3ccccc23)CC1 CHEMBL401747 IC50 730.0 nM
Cc1ccccc1S(=O)(=O)N1CCN(C[C@H](C)Nc2ncnc3c(C)csc23)CC1 CHEMBL429681 IC50 730.0 nM
CCCCCCCCCCCCC1OCC(COP(=O)([O-])O)O1 CHEMBL381470 Ki 745.0 nM
COc1cc(C(=O)N(CCCc2ccccc2)Cc2ccc(Oc3ccc(Cl)cc3C(=O)O)cc2)cc(OC)c1C CHEMBL3975893 IC50 790.0 nM
CCCCCCCCCCCCOP(O)(O)=S CHEMBL191365 EC50 1000.0 nM