CCCCCCCCCCCCCCCCOC(COC)COP([O-])(O)=S CHEMBL2335049 pEC50 0.257 nM
COc1ccccc1Oc1ccc(C(=O)N(CCCc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3936755 IC50 0.4 nM
COc1ccccc1Oc1ccc(C(=O)N(CCCc2cccc(F)c2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3966526 IC50 0.4 nM
CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC CHEMBL2335052 EC50 0.83 nM
O=C(O)c1ccc(CN(CCCc2ccccc2F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3972698 IC50 1.0 nM
O=C(O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3943133 IC50 1.0 nM
CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP([O-])(O)=S CHEMBL2335051 EC50 1.81 nM
COc1ccc(CN(Cc2ccc(C(=O)O)cc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3911605 IC50 2.0 nM
O=C(O)c1ccc(CN(CC2CC2c2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3980736 IC50 2.0 nM
CCCCCCCCCCCCCCCCCOC(COC)COP([O-])(O)=S CHEMBL2335050 EC50 3.0 nM
COc1cccc(CN(Cc2ccc(C(=O)O)cc2)C(=O)c2ccc(Oc3ccccc3F)cc2)c1 CHEMBL3900559 IC50 3.0 nM
CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC CHEMBL2335047 pEC50 3.388 nM
CCCCN(Cc1ccc(C(=O)OC)cc1)C(=O)c1ccc(Oc2ccccc2OC)cc1 CHEMBL3920849 IC50 4.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3945517 IC50 5.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)c(F)c1 CHEMBL3910049 IC50 5.0 nM
COc1cccc(F)c1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3980174 IC50 5.0 nM
CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC CHEMBL357053 pEC50 5.012 nM
O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3891550 IC50 6.0 nM
COc1cccc(CN(Cc2ccc(C(=O)O)c(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)c1 CHEMBL3920145 IC50 6.0 nM
CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC CHEMBL2335048 EC50 6.1 nM
CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC CHEMBL2017139 EC50 6.3 nM
Cc1ccccc1Oc1ccc(C(=O)N(Cc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3942894 IC50 7.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3Cl)cc2)cc1 CHEMBL3951978 IC50 7.0 nM
COc1ccccc1Oc1ccc(C(=O)N(CCC(F)(F)F)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3987061 IC50 7.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(F)(F)F)cc1 CHEMBL3901720 IC50 8.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)nc1 CHEMBL3985179 IC50 8.0 nM
CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC CHEMBL153043 pEC50 8.128 nM
O=C(O)c1ccc(CN(Cc2ccccc2F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3910281 IC50 9.0 nM
O=C(O)c1ccc(CN(C[C@@H](O)Cc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3955284 IC50 9.0 nM
CCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2OC)cc1 CHEMBL3961765 IC50 9.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(C)(F)F)cc1 CHEMBL3892760 IC50 10.0 nM
COc1cc(F)ccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3918970 IC50 10.0 nM
O=C(O)c1ccc(CN(CCCCc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3956413 IC50 11.0 nM
O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)c2ccc(Oc3c(F)cccc3F)cc2)cc1 CHEMBL3918468 IC50 11.0 nM
O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)c2ccc(Oc3c(F)cccc3Cl)cc2)cc1 CHEMBL3914963 IC50 11.0 nM
Cc1cccc(C)c1Oc1ccc(C(=O)N(CCc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3911962 IC50 11.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O CHEMBL117021 EC50 12.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(C)C)cc1 CHEMBL3942192 IC50 12.0 nM
O=C(O)c1ccc(CN(CCC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3914942 IC50 15.0 nM
CCCCCCCCCCCCCCCCOC[C@@H](O)COP(=O)(O)O CHEMBL5416462 EC50 15.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3986752 IC50 16.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3c(F)cccc3Cl)cc2)cc1 CHEMBL3971635 IC50 17.0 nM
Cc1cccc(C)c1Oc1ccc(C(=O)N(Cc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3920547 IC50 17.0 nM
CCCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2F)cc1 CHEMBL3915509 IC50 22.0 nM
O=C(O)c1ccc(CN(CC2CCC2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3976680 IC50 24.0 nM
Cc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3967394 IC50 24.0 nM
O=C(O)c1ccc(CN(CCc2ccccc2)C(=O)c2ccc(Oc3ccccc3Cl)cc2)cc1 CHEMBL3979729 IC50 24.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 CHEMBL3900867 IC50 26.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3c(F)cccc3F)cc2)cc1 CHEMBL3909531 IC50 28.0 nM
Cc1ccccc1Oc1ccc(C(=O)N(CCc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3971670 IC50 29.0 nM
Cc1c(COC(C)(C)C(=O)NCc2ccc(C(=O)O)cc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C(F)(F)F)cc1 CHEMBL5290794 IC50 30.0 nM
COC1CC(CN(Cc2ccc(C(=O)O)cc2)C(=O)c2ccc(Oc3ccccc3F)cc2)C1 CHEMBL3891142 IC50 31.0 nM
Cc1cccc(F)c1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3966386 IC50 31.0 nM
CC(C)CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2F)cc1 CHEMBL3890476 IC50 32.0 nM
COc1ccccc1O[C@H]1CC[C@H](C(=O)N(CCCc2cccc(F)c2)Cc2ccc(C(=O)O)cc2)CC1 CHEMBL3908908 IC50 32.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3ccc4scc(C)c4c3)c(=O)c2cc1OC CHEMBL5404308 IC50 32.0 nM
C#CC1CCN(C(=O)c2cn(-c3ccc4scc(C)c4c3)c(=O)c3cc(OC)c(OC)cc23)CC1 CHEMBL5423970 IC50 32.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3noc4ccc(C)cc34)c(=O)c2cc1OC CHEMBL5275347 IC50 36.0 nM
O=C(O)c1ccc(CN(C[C@H](O)Cc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL4113366 IC50 40.0 nM
O=C(O)c1ccc(CN(CC(F)(F)F)C(=O)c2ccc(Oc3ccccc3Cl)cc2)cc1 CHEMBL3933337 IC50 42.0 nM
O=C(O)c1ccc(CN(CC(F)(F)F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3959098 IC50 43.0 nM
COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(F)F)cc1 CHEMBL3963944 IC50 43.0 nM
Cc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CCC2)cc1 CHEMBL3961807 IC50 44.0 nM
CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2OC)cc1 CHEMBL3923068 IC50 45.0 nM
CCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccc(F)cc2OC)cc1 CHEMBL3985727 IC50 45.0 nM
C#CC1CCN(C(=O)c2cn(-c3cccc(N(C)C)c3)c(=O)c3cc(OC)c(OC)cc23)CC1 CHEMBL5431123 IC50 46.0 nM
O=C(O)c1ccc(CN(CCC2CCC2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3960586 IC50 48.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3ccc4occ(C)c4c3)c(=O)c2cc1OC CHEMBL5437328 IC50 48.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(OCc3ccccc3F)cc2)cc1 CHEMBL3933338 IC50 53.0 nM
O=C(O)c1ccc(CN(CCC2CC2)C(=O)c2ccc(Oc3c(F)cccc3Cl)cc2)cc1 CHEMBL3903990 IC50 58.0 nM
O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)c2ccc(OCc3ccccc3F)cc2)cc1 CHEMBL3920905 IC50 58.0 nM
CCN1CCc2ccc(-n3cc(C(=O)N4CCC(F)CC4)c4cc(OC)c(OC)cc4c3=O)cc21 CHEMBL4208114 IC50 58.0 nM
CCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2F)cc1 CHEMBL3975980 IC50 60.0 nM
CC(C)CN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2F)cc1 CHEMBL3948456 IC50 63.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3cccc(C(C)C)c3)c(=O)c2cc1OC CHEMBL5407873 IC50 63.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3ccc4ccn(C)c4c3)c(=O)c2cc1OC CHEMBL5434733 IC50 64.0 nM
CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O CHEMBL364797 pEC50 67.61 nM
COc1ccc(F)cc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3921376 IC50 68.0 nM
COc1cc2c(C(=O)N3CCC(F)CC3)cn(-c3ccc4scc(C)c4c3)c(=O)c2cc1OC CHEMBL5435702 IC50 69.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cn2)cc1 CHEMBL3972525 IC50 74.0 nM
COc1cc2c(C(=O)N3CCC(F)CC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5415670 IC50 79.0 nM
O=C(O)c1ccc(CN(CCC(F)(F)F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3896384 IC50 83.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5393829 IC50 87.0 nM
Cc1cccc(F)c1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CCC2)cc1 CHEMBL3895064 IC50 89.0 nM
COc1ccccc1Oc1cnc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)nc1 CHEMBL3897650 IC50 91.0 nM
CC#CC1CCN(C(=O)c2cn(-c3cccc(N(C)C)c3)c(=O)c3cc(OC)c(OC)cc23)CC1 CHEMBL5433243 IC50 91.0 nM
CC(F)(F)CN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2F)cc1 CHEMBL3943469 IC50 98.0 nM
Cc1cccc(C)c1Oc1ccc(C(=O)N(CCC(C)C)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3942946 IC50 99.0 nM
COc1cc2c(C(=O)N3CCC(C#N)CC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5394748 IC50 102.0 nM
O=C(O)c1ccc(CN(CCc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3939578 IC50 120.0 nM
CCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ncc(Oc2ccccc2OC)cn1 CHEMBL3935056 IC50 120.0 nM
O=C(O)c1ccc(CN(CCC2CC2)C(=O)c2ccc(Oc3c(F)cccc3F)cc2)cc1 CHEMBL3893992 IC50 140.0 nM
Cc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(F)(F)F)cc1 CHEMBL3924401 IC50 140.0 nM
CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2Cl)cc1 CHEMBL3942927 IC50 140.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)COP(=O)(O)O CHEMBL1222042 EC50 140.0 nM
COc1cc2c(C(=O)N3CCC(F)CC3)cn(-c3ccc4occ(C)c4c3)c(=O)c2cc1OC CHEMBL5407923 IC50 144.0 nM
COc1cc2c(C(=O)N3CCC(C)CC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5422543 IC50 160.0 nM
O=C(O)c1ccc(CN(CC(F)F)C(=O)c2ccc(Oc3ccccc3Cl)cc2)cc1 CHEMBL3948271 IC50 170.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3cccc(C(C)(C)C)c3)c(=O)c2cc1OC CHEMBL5431688 IC50 173.0 nM
COc1ccccc1O[C@H]1CC[C@H](C(=O)N(Cc2ccccc2)Cc2ccc(C(=O)O)cc2)CC1 CHEMBL3953043 IC50 180.0 nM
N#Cc1ccccc1Oc1ccc(C(=O)N(Cc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL3959515 IC50 200.0 nM
COc1cc2c(C(=O)N3CCC(F)CC3)cn(-c3cccc(C(C)C)c3)c(=O)c2cc1OC CHEMBL5440323 IC50 200.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3ccc4cccc(C)c4c3)c(=O)c2cc1OC CHEMBL5424487 IC50 210.0 nM
COc1cc2c(C(=O)N3C4CCCC3CC4)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5407955 IC50 230.0 nM
CCCCCOc1cc2c(C(=O)N3CCC(F)CC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5395745 IC50 230.0 nM
O=C(O)c1ccc(CN(CCc2ccccc2)C(=O)c2ccc(Oc3ccccc3C(F)(F)F)cc2)cc1 CHEMBL3935519 IC50 260.0 nM
COc1cc2c(C(=O)N3CCCC(C)C3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5412574 IC50 260.0 nM
O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(Oc3ccc([N+](=O)[O-])cc3)c1)C2=O CHEMBL604677 Ki 292.0 nM
COc1cc2c(C(=O)N3CCCCCCC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5436020 IC50 301.0 nM
COc1cc2c(C(=O)N(C)OC)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5423951 IC50 320.0 nM
O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ncc(Oc3ccccc3F)cn2)cc1 CHEMBL3907299 IC50 350.0 nM
COc1cc2c(=O)n(-c3cccc(N(C)C)c3)cc(C(=O)N3CCC(F)CC3)c2cc1OC(C)C CHEMBL5418239 IC50 369.0 nM
O=C(O)c1ccc(CN(CC2CCC2)C(=O)c2ccc(OCc3ccccc3F)cc2)cc1 CHEMBL3948718 IC50 370.0 nM
COc1ccccc1OC1CCC(C(=O)N(CCCc2cccc(F)c2)Cc2ccc(C(=O)O)cc2)CC1 CHEMBL3975225 IC50 410.0 nM
CCOc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC2CC2)cc1 CHEMBL3927774 IC50 460.0 nM
CCCOc1cc2c(C(=O)N3CCC(F)CC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5439576 IC50 480.0 nM
COc1cc2c(=O)n(-c3cccc(N(C)C)c3)cc(C(=O)N3CCC(F)CC3)c2cc1OC1CCCCC1 CHEMBL5400161 IC50 510.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3cccc(OC(C)C)c3)c(=O)c2cc1OC CHEMBL5425224 IC50 630.0 nM
COc1cc2c(C(=O)N3CCC(OC)CC3)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5395157 IC50 640.0 nM
COc1cc2c(C(=O)N3CCCCC3)cn(-c3ccc4sccc4c3)c(=O)c2cc1OC CHEMBL5406168 IC50 640.0 nM
O=C(O)c1ccc(CN(CC(F)F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 CHEMBL3963121 IC50 690.0 nM
O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)C2CCC(Oc3ccccc3F)CC2)cc1 CHEMBL3947618 IC50 690.0 nM
COc1cccc(-n2nc(C(=O)O)cc2-c2ccc(C3CCCCC3)c(Cl)c2)c1 CHEMBL2058156 IC50 800.0 nM
CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2F)cc1 CHEMBL3973570 IC50 840.0 nM
CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2C)cc1 CHEMBL3908939 IC50 890.0 nM
COc1cc2c(=O)n(-c3cccc(N(C)C)c3)cc(C(=O)N3CCC(F)CC3)c2cc1OC1CCCC1 CHEMBL5399620 IC50 890.0 nM
COc1cc2c(C(=O)N3CCCCC3C)cn(-c3cccc(N(C)C)c3)c(=O)c2cc1OC CHEMBL5428686 IC50 990.0 nM