C#CCN(C)CCCOc1ccc(Cl)cc1Cl CHEMBL8706 IC50 0.004 nM
Cc1c(C(=O)CC(C#N)C#N)c(=O)n(-c2ccccc2)n1C CHEMBL5271774 Ki 0.014 nM
COc1ccc2c(c1)-c1nnc(-c3cccc(C(F)(F)F)c3)cc1C2=O CHEMBL209413 IC50 0.1 nM
CNC(=S)N1N=C(c2ccccc2)CC1c1ccc(F)cc1 CHEMBL5269241 Ki 0.1 nM
CNC(=S)N1N=C(c2ccc(Cl)cc2)CC1c1ccc(F)cc1 CHEMBL5283319 Ki 0.1 nM
CNC(=S)N1N=C(c2ccc(C)cc2)CC1c1ccc(F)cc1 CHEMBL5276967 Ki 0.1 nM
CNC(=S)N1N=C(c2ccc(OC)cc2)CC1c1ccc(F)cc1 CHEMBL5272518 Ki 0.1 nM
CCNC(=S)N1N=C(c2ccccc2)CC1c1ccc(F)cc1 CHEMBL5291452 Ki 0.1 nM
CCNC(=S)N1N=C(c2ccc(Cl)cc2)CC1c1ccc(F)cc1 CHEMBL5280524 Ki 0.1 nM
CCNC(=S)N1N=C(c2ccc(C)cc2)CC1c1ccc(F)cc1 CHEMBL5272772 Ki 0.1 nM
CCNC(=S)N1N=C(c2ccc(OC)cc2)CC1c1ccc(F)cc1 CHEMBL5271570 Ki 0.1 nM
Fc1ccc(C2CC(c3ccccc3)=NN2C(=S)Nc2ccccc2)cc1 CHEMBL5268306 Ki 0.1 nM
COc1ccc(C2=NN(C(=S)Nc3ccccc3)C(c3ccc(F)cc3)C2)cc1 CHEMBL5273835 Ki 0.1 nM
Fc1ccc(C2CC(c3ccc(Cl)cc3)=NN2C(=S)Nc2ccccc2)cc1 CHEMBL5284012 Ki 0.1 nM
C=CCNC(=S)N1N=C(c2ccccc2)CC1c1ccc(F)cc1 CHEMBL5275680 Ki 0.1 nM
C=CCNC(=S)N1N=C(c2ccc(Cl)cc2)CC1c1ccc(F)cc1 CHEMBL5290358 Ki 0.1 nM
C=CCNC(=S)N1N=C(c2ccc(OC)cc2)CC1c1ccc(F)cc1 CHEMBL5284128 Ki 0.1 nM
Cc1ccc(C2=NN(C(=S)Nc3ccccc3)C(c3ccc(F)cc3)C2)cc1 CHEMBL5282135 Ki 0.1 nM
C=CCNC(=S)N1N=C(c2ccc(C)cc2)CC1c1ccc(F)cc1 CHEMBL5270226 Ki 0.1 nM
C#CCN(C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C CHEMBL1929421 IC50 0.27 nM
Cc1c(-c2cc(C#N)c(N)o2)c(=O)n(-c2ccccc2)n1C CHEMBL5270286 Ki 0.346 nM
Cn1ncc2cc(C(=O)Nc3ccc(Cl)c(Cl)c3)ccc21 CHEMBL3319256 pIC50 0.389 nM
C#CCN(C)CCCOc1cc(NCc2ccc(C(=O)NO)cc2)ccc1Cl CHEMBL5178014 IC50 0.4 nM
COCCn1ncc2cc(C(=O)Nc3ccc(Cl)c(Cl)c3)ccc21 CHEMBL4104691 Ki 0.48 nM
O=C(NCCN1CCOCC1)c1ccc(Cl)cc1 CHEMBL86304 Ki 0.5 nM
Cn1ncc2cc(C(=O)Nc3ccc(F)c(Cl)c3)ccc21 CHEMBL4061639 pIC50 0.6607 nM
c1ccc(Cc2nc3ccccc3n3cnnc23)cc1 CHEMBL1256153 IC50 0.7 nM
C#CCN(C)CC(=C)c1ccoc1 CHEMBL3415804 IC50 0.72 nM
COc1cc2c3c(nccc3c1)-c1ccccc1C2=O CHEMBL1651055 IC50 0.83 nM
C#CCN(C)CC(=C)c1ccc(Br)cc1 CHEMBL3415795 IC50 0.85 nM
C#CCN(C)CC(=C)c1ccc(Cl)c(Cl)c1 CHEMBL3415817 IC50 1.0 nM
COc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccccc43)C(c3ccccc3Cl)C2)cc1 CHEMBL4748517 Ki 1.0 nM
O=C(Cn1c(=O)oc2ccccc21)N/N=C(\C=C\c1ccccc1)c1ccccc1 CHEMBL4787516 Ki 1.0 nM
COc1cccc(/C=C/C(=N\NC(=O)Cn2c(=O)oc3ccccc32)c2ccccc2)c1 CHEMBL4761363 Ki 1.0 nM
COc1ccc(C(/C=C/c2ccccc2Cl)=N/NC(=O)Cn2c(=O)oc3ccccc32)cc1 CHEMBL4757953 Ki 1.0 nM
COc1ccccc1/C=C/C(=N\NC(=O)Cn1c(=O)oc2ccc(Cl)cc21)c1ccccc1 CHEMBL4787184 Ki 1.0 nM
COc1ccccc1C(/C=C/c1ccccc1Cl)=N/NC(=O)Cn1c(=O)oc2ccc(Cl)cc21 CHEMBL4762228 Ki 1.0 nM
COc1ccc2c(c1)[nH]c1c(C)nccc12 CHEMBL269538 IC50 1.0 nM
C#CCN(C)CC(=C)c1cccc(COc2ccc(F)cc2)c1 CHEMBL3415783 IC50 1.4 nM
Cn1cc2cc(C(=O)Nc3ccc(Cl)c(Cl)c3)ccc2n1 CHEMBL3319257 pIC50 1.445 nM
C/C(=N\NC(=O)Cn1c(=O)c(Cc2ccccc2)nc2ccccc21)c1ccc(O)cc1 CHEMBL3408926 IC50 1.6 nM
COC[C@H]1CN(c2ccc(OCC[C@@H](O)C(F)(F)F)cc2)C(=O)O1 CHEMBL416578 Ri 1.9 nM
C#CCNCC(=C)c1cccc(OCc2cccc(F)c2)c1 CHEMBL3415611 IC50 1.9 nM
COc1ccccc1C1CC(c2ccc(O)cc2)=NN1C(C)=O CHEMBL293004 Ki 2.0 nM
NNC(=O)CN1C(=O)c2ccccc2NC1c1ccc2c(c1)OCO2 CHEMBL3585822 IC50 2.1 nM
C#CCN(C)CC(=C)c1ccc(F)c(F)c1 CHEMBL3415816 IC50 2.3 nM
COc1ccc2c3c([nH]c2c1)C(C)=NCC3 CHEMBL340807 IC50 2.5 nM
O=C(c1ccccc1)c1nc2ccccc2n2c(-c3ccccc3)nnc12 CHEMBL1258839 IC50 2.7 nM
CN(C)c1ccc(-c2nnc3c(C(=O)c4ccccc4)nc4ccccc4n23)cc1 CHEMBL1258610 IC50 2.7 nM
C/C(=N\Nc1nc2ccccc2nc1Cc1ccccc1)c1ccc(O)cc1 CHEMBL1257814 IC50 2.8 nM
Cc1ccc(NC(=S)N/N=C/c2ccc(-n3nc4c(c3C)N(C)S(=O)(=O)c3ccccc3-4)cc2)cc1 CHEMBL4161420 IC50 3.0 nM
Oc1ccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1 CHEMBL1257932 IC50 3.4 nM
C#CCN(C)CC(=C)c1cccs1 CHEMBL3415805 IC50 3.4 nM
Cc1nccc2c1[nH]c1cc(OCCCC(F)(F)F)ccc12 CHEMBL1645547 Ki 3.6 nM
C#CCN(C)CC(=C)c1ccc(F)cc1 CHEMBL3415798 IC50 3.7 nM
CC(=O)COc1ccc2c3c(c(=O)oc2c1C)CCCC3 CHEMBL488073 IC50 3.78 nM
Cc1nccc2c1[nH]c1cc(OCC(C)C)ccc12 CHEMBL1645545 Ki 3.9 nM
C#CCN(C)CC(=C)c1ccc(Cl)cc1 CHEMBL3415793 IC50 3.9 nM
COc1ccccc1C1CC(c2ccc(O)cc2O)=NN1C(C)=O CHEMBL303112 Ki 4.0 nM
Cc1ccc(C2CC(c3ccccc3O)=NN2C(=O)Oc2ccccc2)cc1 CHEMBL2437020 Ki 4.0 nM
COc1ccc(-c2[nH]c3cc(C#N)c(C#N)cc3c2Cl)cc1 CHEMBL3398530 IC50 4.0 nM
Cc1ccc(C2CC(c3ccccc3)=NN2C(=O)Cn2c(=O)oc3ccccc32)cc1 CHEMBL4794193 Ki 4.0 nM
COc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(Cl)cc43)C(c3ccccc3)C2)cc1 CHEMBL4788778 Ki 4.0 nM
COc1ccccc1C(/C=C/c1ccccc1Cl)=N/NC(=O)Cn1c(=O)oc2ccccc21 CHEMBL4764828 Ki 4.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCCN4CCN(c5ccccc5F)CC4)cc1c23 CHEMBL5203412 IC50 4.0 nM
C#CCN(C)CCCOc1cc(NCc2ccc(/C=C/C(=O)NO)cc2)ccc1Cl CHEMBL5191350 IC50 4.0 nM
C#CCN(C)CC(=C)c1ccc(Cl)c(C)c1 CHEMBL3415819 IC50 4.1 nM
Cc1nccc2c1[nH]c1cc(OCC3CCCCC3)ccc12 CHEMBL1645548 Ki 4.3 nM
Fc1ccc(-c2csc(N/N=C/c3ccc(N4CCOCC4)cc3)n2)c(F)c1 CHEMBL4169527 Ki 4.4 nM
COC[C@H]1CN(n2cccc2)C(=O)O1 CHEMBL18334 Ki 4.9 nM
C=CCOc1ccc2c(c1)[nH]c1c(C)nccc12 CHEMBL1645544 Ki 5.0 nM
Cc1nccc2c1[nH]c1cc(OCCc3ccccc3)ccc12 CHEMBL1645550 Ki 5.0 nM
COc1cccc(C2CC(c3ccccc3)=NN2C(=O)Cn2c(=O)oc3ccc(C)cc32)c1 CHEMBL4744188 Ki 5.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCN4CCN(c5ccccc5F)CC4)cc1c23 CHEMBL5186035 IC50 5.0 nM
Cc1ccc(C(=O)NNC(=O)Cn2c(=O)c(Cc3ccccc3)nc3ccccc32)cc1 CHEMBL3408913 IC50 5.332 nM
C#CCN(C)Cc1ccc[nH]1 CHEMBL220116 Ki 5.4 nM
O=C(Cn1c(=O)c(Cc2ccccc2)nc2ccccc21)NNC(=S)Nc1ccccc1 CHEMBL4852596 IC50 5.413 nM
C#CCNCc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C CHEMBL3127967 pIC50 5.495 nM
CN1C(=N)N(C)/C(=C/c2c[nH]c3cc(Br)ccc23)C1=O CHEMBL463249 IC50 5.6 nM
Clc1ccccc1/C=N/Nc1nc2ccccc2nc1Cc1ccccc1 CHEMBL1257571 IC50 5.8 nM
C#CCN(C)CC(=C)c1cccc(OCc2ccccc2)c1 CHEMBL3415802 IC50 6.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc1c23 CHEMBL5209523 IC50 6.0 nM
Clc1ccccc1-c1nnc2c(Cc3ccccc3)nc3ccccc3n12 CHEMBL1258954 IC50 6.1 nM
COc1ccc(-c2nnc3c(C(=O)c4ccccc4)nc4ccccc4n23)cc1 CHEMBL1258500 IC50 6.2 nM
C(=N/Nc1nc2ccccc2nc1Cc1ccccc1)\c1ccc2c(c1)OCO2 CHEMBL1257340 IC50 6.3 nM
C#CCN(C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4C)CC3)ccc2n1C CHEMBL3407581 IC50 6.3 nM
C#CCNCC(=C)c1cccc(COc2ccccc2)c1 CHEMBL3415786 IC50 6.3 nM
C#CCN(C)CC(=C)c1ccc(F)c(Cl)c1 CHEMBL3415820 IC50 6.3 nM
N#Cc1ccc(OCc2ccc(Br)cc2)cc1C#N CHEMBL2204752 IC50 6.6 nM
C#CCN(C)CC(=C)c1cccc(OCc2cccc(OC)c2)c1 CHEMBL3415780 IC50 6.6 nM
Fc1ccc(-c2csc(N/N=C/c3ccc(N4CCOCC4)cc3)n2)cc1 CHEMBL4172923 Ki 6.6 nM
O=C(Nc1ccc(F)c(F)c1)c1ccc2[nH]ncc2c1 CHEMBL3319248 pIC50 6.607 nM
COc1ccc(-c2nnc3c(C(=O)c4ccccc4)nc4ccccc4n23)cc1OC CHEMBL1258955 IC50 6.8 nM
Cc1cc(=O)oc2c(C)c(OC3CCCC3=O)ccc12 CHEMBL488916 IC50 7.16 nM
CC1(C)C(N[C@@H]2C[C@H]2c2ccccc2)CCC1N[C@@H]1C[C@H]1c1ccccc1 CHEMBL5196914 IC50 7.29 nM
C#CCN(C)CC(=C)c1cccc(CNc2ccccc2)c1 CHEMBL3415615 IC50 7.4 nM
C#CCN(C)CC(=C)c1cccc(F)c1 CHEMBL3415797 IC50 7.6 nM
CC(=O)N1N=C(c2ccc(O)cc2)CC1c1cccc(C)c1 CHEMBL304241 IC50 8.0 nM
COc1cccc(C2CC(c3ccccc3)=NN2C(=O)Cn2c(=O)oc3ccccc32)c1 CHEMBL4740141 Ki 8.0 nM
Cc1ccc(C2CC(c3ccccc3)=NN2C(=O)Cn2c(=O)oc3ccc(C)cc32)cc1 CHEMBL4778941 Ki 8.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCN4CCN(c5ccccc5F)CC4)cc1c23 CHEMBL5195369 IC50 8.0 nM
C/C(=N\NCN1C(=O)S/C(=C\c2ccc(OCc3ccccc3)cc2)C1=O)c1cccs1 CHEMBL5219078 IC50 8.0 nM
Cn1cc2cc(C(=O)Nc3ccc(F)c(Cl)c3)ccc2n1 CHEMBL4089754 pIC50 8.128 nM
CC(=O)N1N=C(c2ccc(O)cc2)CC1c1ccccc1Cl CHEMBL63223 IC50 8.6 nM
O=[N+]([O-])c1ccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1 CHEMBL1258274 IC50 8.8 nM
CC(=O)N1N=C(c2ccc(O)cc2O)CC1c1ccc(C)cc1 CHEMBL62743 IC50 9.0 nM
COc1ccc(C2CC(c3ccc(O)cc3O)=NN2C(C)=O)cc1 CHEMBL291647 IC50 9.0 nM
COc1ccc(C2CC(c3ccc(O)cc3)=NN2C(C)=O)cc1 CHEMBL65761 IC50 9.0 nM
C#CCN(C)CC(=C)c1cccc(COc2ccc(OC)cc2)c1 CHEMBL3415785 IC50 9.0 nM
COc1ccc(C2CC(c3ccccc3)=NN2C(=O)Cn2c(=O)oc3ccccc32)cc1OC CHEMBL4783604 Ki 9.0 nM
COc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(C)cc43)C(c3cccc(OC)c3OC)C2)cc1 CHEMBL4763998 Ki 9.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCN4CCN(c5ccccc5)CC4)cc1c23 CHEMBL5195988 IC50 9.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCCN4CCN(c5ccccc5)CC4)cc1c23 CHEMBL5196277 IC50 9.0 nM
O=c1[nH]c2ccc(OCc3ccc(Br)cc3)cc2c(=O)o1 CHEMBL5218784 IC50 9.5 nM
CN(C)c1ccc(-c2nnc3c(C(=O)c4ccccc4)nc4ccccc4n23)cc1Br CHEMBL1258611 IC50 9.6 nM
C#CCCCCOc1ccc2cc(C(=O)OC)c(=O)oc2c1 CHEMBL3121784 IC50 9.64 nM
C/C(=N\Nc1nc2ccccc2nc1Cc1ccccc1)c1ccc(N)cc1 CHEMBL1258160 IC50 9.8 nM
Brc1cccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)c1 CHEMBL1258275 IC50 9.8 nM
COc1ccc(C2CC(c3ccc(O)cc3)=NN2C(C)=O)c(OC)c1 CHEMBL65252 IC50 10.0 nM
CC(=O)N1N=C(c2ccc(O)cc2O)CC1c1ccc(Cl)cc1 CHEMBL418480 IC50 10.0 nM
CC(=O)N1N=C(c2ccc(O)cc2)CC1c1cccc(Cl)c1 CHEMBL303594 IC50 10.0 nM
CCc1cccc2c1S(=O)(=O)c1ccccc1O2 CHEMBL66225 Ki 10.0 nM
Cc1cccc(/C=C/C(=N/NC(=O)c2snnc2C)c2ccc(Cl)cc2)c1 CHEMBL3310025 Ki 10.0 nM
Cc1ccc(/C=C/C(=N/NC(=O)c2snnc2C)c2ccc(O)cc2)cc1 CHEMBL3310028 Ki 10.0 nM
Cc1ccccc1NC(=S)N/N=C/c1ccc(-n2nc3c(c2C)N(C)S(=O)(=O)c2ccccc2-3)cc1 CHEMBL4169343 IC50 10.0 nM
Cc1cccc(C)c1NC(=S)N/N=C/c1ccc(-n2nc3c(c2C)N(C)S(=O)(=O)c2ccccc2-3)cc1 CHEMBL4174892 IC50 10.0 nM
COc1ccc(C(/C=C/c2cccc(OC)c2OC)=N/NC(=O)Cn2c(=O)oc3ccc(Cl)cc32)cc1 CHEMBL4753849 Ki 10.0 nM
O=C1CCCc2ccc(OCc3ccccc3)cc21 CHEMBL5185721 IC50 10.0 nM
C/C(=N\NCCCN1C(=O)S/C(=C\c2ccc(OCc3ccccc3)cc2)C1=O)c1cccs1 CHEMBL5220624 IC50 10.0 nM
CC(C)c1ccc(COc2ccc3[nH]c(=O)oc(=O)c3c2)cc1 CHEMBL5219958 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)C(=O)c1ccccc1S2(=O)=O CHEMBL65156 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O CHEMBL63458 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1cc(C)ccc1C2=O CHEMBL63510 IC50 10.0 nM
CCc1ccc2c(c1)S(=O)(=O)c1cc(NC(C)=O)ccc1C2=O CHEMBL417566 IC50 10.0 nM
CCCc1ccc2c(c1)S(=O)(=O)c1cc(NC(C)=O)ccc1C2=O CHEMBL63141 IC50 10.0 nM
O=CN(C=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O CHEMBL63782 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1ccccc1O2 CHEMBL63934 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1ccccc1N2 CHEMBL63678 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1ccccc1N2C CHEMBL292052 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1cc(NC(C)=O)ccc1N2C CHEMBL66260 IC50 10.0 nM
CC(=O)Nc1cccc2c1C(=O)c1ccccc1C2=O CHEMBL65583 IC50 10.0 nM
CC(=O)Nc1ccc2c(c1)C(=O)c1ccccc1C2=O CHEMBL304069 IC50 10.0 nM
CC(=O)Nc1ccc2c(O)c3ccccc3nc2c1 CHEMBL304484 IC50 10.0 nM
CC(=O)Nc1cc2c(cc1NC(C)=O)S(=O)(=O)c1ccccc1C2 CHEMBL5270901 IC50 10.0 nM
NC(=S)NNC(=O)Cn1c(=O)c(Cc2ccccc2)nc2ccccc21 CHEMBL4871376 IC50 10.48 nM
Cc1c(C)c2ccc(OS(=O)(=O)c3ccc([N+](=O)[O-])cc3)cc2oc1=O CHEMBL145451 IC50 10.7 nM
COc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccccc43)C(c3ccccc3)C2)cc1 CHEMBL4740937 Ki 11.0 nM
COc1cccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(C)cc43)C(c3ccccc3Cl)C2)c1 CHEMBL4741789 Ki 11.0 nM
COc1ccccc1C(/C=C/c1ccccc1Cl)=N/NC(=O)Cn1c(=O)oc2ccc(C)cc21 CHEMBL4751649 Ki 11.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc1c23 CHEMBL5173754 IC50 11.0 nM
COc1ccc2c3ccnc(C)c3n(C)c2c1 CHEMBL44889 IC50 11.0 nM
C#CCN(C)Cc1ccccc1 CHEMBL673 IC50 11.52 nM
CCOC(=O)NNC(=O)Cn1c(=O)c(Cc2ccccc2)nc2ccccc21 CHEMBL4862110 IC50 11.95 nM
Cc1ccc([C@H]2CC(c3cc(Cl)ccc3O)=NN2C(=O)c2ccccc2)cc1 CHEMBL3310005 Ki 12.0 nM
Cc1ccc(/C=C/C(=N/NC(=O)c2snnc2C)c2ccc(Cl)cc2)cc1 CHEMBL3310024 Ki 12.0 nM
COc1ccc(/C=C/C(=N/NC(=O)c2snnc2C)c2ccc(Cl)cc2)cc1 CHEMBL3310026 Ki 12.0 nM
COc1ccc(C(/C=C/c2ccccc2)=N/NC(=O)Cn2c(=O)oc3ccc(C)cc32)cc1 CHEMBL4781759 Ki 12.0 nM
Cc1nccc2c1[nH]c1cc(OCc3ccccc3)ccc12 CHEMBL1645549 Ki 12.6 nM
COC1=Cc2ccnc3c2c(cc2ccccc23)C1=O CHEMBL1917530 IC50 13.0 nM
C#CCN(C)CC(=C)c1cccc(OCc2ccc(F)cc2)c1 CHEMBL3415779 IC50 13.0 nM
COc1ccccc1C1=NN(C(=O)Cn2c(=O)oc3ccccc32)C(c2ccccc2Cl)C1 CHEMBL4778703 Ki 13.0 nM
C/C(=N\NCN1C(=O)S/C(=C\c2ccc(OCc3ccccc3)cc2)C1=O)c1ccncc1 CHEMBL5219886 IC50 13.0 nM
COc1cc2c3c(c1)C(=O)c1ccccc1C3=NCC2 CHEMBL1651054 IC50 14.0 nM
Cc1ccc(-c2[nH]c3cc(C#N)c(C#N)cc3c2Cl)cc1 CHEMBL3398531 IC50 14.0 nM
C#CCN(C)CC(=C)c1cccc(COc2cccc(F)c2)c1 CHEMBL3415782 IC50 14.0 nM
COc1ccc2c(=O)c(/C=C/c3ccc(F)cc3)coc2c1 CHEMBL4865050 IC50 14.0 nM
COc1ccccc1N1CCN(CCCCCOc2cc3c4c(nccc4c2)-c2ccccc2C3=O)CC1 CHEMBL5200833 IC50 14.0 nM
C#CCN(C)CCCOc1cc(N)c(Cl)cc1Cl CHEMBL5439810 IC50 14.8 nM
COc1ccc2c3cc[n+](C)c(C)c3n(C)c2c1 CHEMBL139947 Ki 15.0 nM
Cc1cc(=O)oc2c(NC(=O)c3ccccc3)c(O)ccc12 CHEMBL5396287 IC50 15.0 nM
CC(C)(C)OC(=O)C(Cc1ccccc1)NC(=O)Cn1c(=O)c(Cc2ccccc2)nc2ccccc21 CHEMBL3408929 IC50 15.19 nM
C#CCN(C)CC(=C)c1ccc(F)c(C)c1 CHEMBL3415818 IC50 17.0 nM
COc1ccc2oc(/C=C/c3ccc(Cl)cc3)cc(=O)c2c1 CHEMBL5277689 IC50 17.0 nM
O=[N+]([O-])c1ccc(C2CC(c3c4ccccc4cc4ccccc34)=NN2)cc1 CHEMBL1760713 Ki 17.08 nM
C/N=C1\N(C)C(=O)/C(=C\c2c[nH]c3cc(Br)ccc23)N1C CHEMBL2058428 IC50 18.0 nM
C#CCN(C)CC(=C)c1ccc(C)c(C)c1 CHEMBL3415815 IC50 18.0 nM
COc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(C)cc43)C(c3ccccc3Cl)C2)cc1 CHEMBL4753525 Ki 18.0 nM
C#CCOc1ccc(-c2cc(-c3ccc(OCCN4CCOCC4)cc3)nc(N)n2)cc1 CHEMBL4790416 IC50 18.34 nM
Cc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccccc43)C(c3ccccc3)C2)cc1 CHEMBL4754619 Ki 19.0 nM
C#CCNC1CCc2c(OC(=O)N(C)CC)cccc21 CHEMBL1193656 IC50 19.0 nM
O=C(Cl)C1=Cc2cc(Br)ccc2CC1=O CHEMBL125541 Log IC50 19.95 nM
C#CCN(C)CC(=C)c1cccc(COc2ccccc2)c1 CHEMBL3415613 IC50 20.0 nM
C#CCN(C)CC(=C)c1cccc(COc2cccc(OC)c2)c1 CHEMBL3415784 IC50 20.0 nM
Cc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(Cl)cc43)C(c3ccccc3)C2)cc1 CHEMBL4783502 Ki 20.0 nM
C#CCN(C)CCCOc1cc(NC(=O)CCCCCCCC(=O)NO)ccc1Cl CHEMBL5187984 IC50 20.0 nM
COc1cc2c(cc1OC)C(=O)/C(=C/c1ccc(N(C)C)cc1)C2 CHEMBL2220507 IC50 20.0 nM
N[C@]1(CCc2ccccc2)C[C@H]1c1ccccc1 CHEMBL3330334 IC50 21.4 nM
CCCCSc1ccc(C[C@H](C)N)cc1 CHEMBL387778 Ki 22.0 nM
O=C(c1ccccc1)c1nc2ccccc2n2c(-c3ccc([N+](=O)[O-])cc3)nnc12 CHEMBL1258718 IC50 22.0 nM
COc1ccc2c(=O)c(/C=C/c3ccc(O)cc3)coc2c1 CHEMBL4851829 IC50 22.0 nM
Cc1cc(=O)oc2c(NC(=O)/C=C/c3ccccc3)c(O)ccc12 CHEMBL5402751 IC50 22.0 nM
Cn1c(=O)c2c(nc(OCc3cccc(Br)c3)n2C)n(C)c1=O CHEMBL602464 Ki 23.0 nM
COc1ccc2oc(-n3cncn3)cc(=O)c2c1 CHEMBL5266265 IC50 23.0 nM
O=c1c(Cc2ccccc2)nc2ccccc2n1CC(O)CO CHEMBL4878125 IC50 23.95 nM
N#Cc1cccc(COc2ccc3c(c2)CCCC3=O)c1 CHEMBL3288301 IC50 24.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3416427 IC50 24.0 nM
C#CCN(C)CCCOc1cc(O)c(Cl)cc1Cl CHEMBL5400787 IC50 24.4 nM
Cc1nccc2c1[nH]c1cc(OCc3cccnc3)ccc12 CHEMBL1645552 Ki 24.9 nM
O=C1OCc2ccc(OCCCc3ccccc3)cc21 CHEMBL2391876 Ki 25.0 nM
N[C@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3416432 IC50 25.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(NC(=O)OCc3ccccc3)c2)cc1 CHEMBL3780674 IC50 25.0 nM
COc1ccc2c(=O)c(/C=C/c3ccc(Cl)cc3)coc2c1 CHEMBL4847545 IC50 25.0 nM
CCN(C)c1ccc(/C=C2\Oc3cc(O)cc(O)c3C2=O)cc1 CHEMBL3786785 IC50 27.9 nM
COc1cccc(C2CC(c3ccc(C)cc3)=NN2C(=O)Cn2c(=O)oc3ccccc32)c1OC CHEMBL4743441 Ki 28.0 nM
Cc1cc(=O)c(O)c(CO)n1CCCn1cc(COc2ccc3ccc(=O)oc3c2)nn1 CHEMBL4751815 IC50 28.0 nM
CN1CCN(c2ccc(/C=N/Nc3ccccc3)cc2)CC1 CHEMBL5267475 IC50 28.0 nM
Cc1nccc2c1[nH]c1cc(OCCO)ccc12 CHEMBL14355 Ki 28.4 nM
O=C(Cl)C1=Cc2cc([N+](=O)[O-])ccc2CC1=O CHEMBL331290 Log IC50 28.84 nM
Cc1ccc2c(c1)C=C(C(=O)Cl)C(=O)C2 CHEMBL332164 Log IC50 28.84 nM
COc1cc(/C(C)=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc(OC)c1OC CHEMBL1257341 IC50 29.0 nM
C/N=C1\NC(=O)/C(=C\c2c[nH]c3cc(Br)ccc23)N1C CHEMBL2058417 IC50 29.0 nM
Cc1nccc2c1[nH]c1ccccc12 CHEMBL12014 IC50 29.0 nM
CCc1ccc(/C=C/C(=O)c2ccc3c(c2)OCO3)cc1 CHEMBL5401725 IC50 29.0 nM
COCCOc1ccc2c(c1)[nH]c1c(C)nccc12 CHEMBL1645546 Ki 29.5 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccc(N3CCOC3=O)cc2)cc1 CHEMBL3780524 IC50 29.7 nM
CCCSc1ccc(C[C@H](C)N)cc1 CHEMBL229472 Ki 30.0 nM
O=C(Oc1ccccc1)N1N=C(c2ccccc2O)CC1c1ccc(Cl)cc1 CHEMBL2437021 Ki 30.0 nM
C#CCN(C)CC(=C)c1cccc(Cl)c1 CHEMBL3415792 IC50 30.0 nM
C#CCN(C)CCCOc1ccc(NC(=O)CCCCCCC(=O)NO)cc1Cl CHEMBL5182215 IC50 30.0 nM
C[C@H](NCc1ccc(OCc2cccc(F)c2)cc1)C(N)=O CHEMBL396778 IC50 30.0 nM
COCc1ccc2c(c1)[nH]c1c(C)nccc12 CHEMBL5267999 IC50 30.0 nM
O=C(Cl)C1=Cc2cc(Cl)ccc2CC1=O CHEMBL340590 Log IC50 30.2 nM
NC1CC1c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3416425 IC50 31.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3546846 IC50 31.2 nM
C#CCN[C@@H]1CCc2ccccc21 CHEMBL887 IC50 32.0 nM
O=[N+]([O-])c1cccc(C2CC(c3c4ccccc4cc4ccccc34)=NN2)c1 CHEMBL1760721 Ki 32.16 nM
COCCNc1nnc(SCC(=O)N(Cc2cccc([N+](=O)[O-])c2)c2ccc(F)cc2)s1 CHEMBL4798970 Ki 33.0 nM
Cc1ccc(/C=C/C(=N\NC(=O)c2cccs2)c2ccc(Cl)cc2)cc1 CHEMBL3310023 Ki 34.0 nM
COc1ccc(/C=C/C(=N\NC(=O)c2ccc(OC)cc2)c2ccc(Cl)cc2)cc1 CHEMBL3310027 Ki 34.0 nM
C#CCN(C)CC(=C)Cc1ccc(F)c(F)c1 CHEMBL3415789 IC50 34.0 nM
O=C1c2ccccc2-c2nccc3cc(O)cc1c23 CHEMBL1917529 IC50 35.0 nM
CN1C(=N)N(C)/C(=C/c2c[nH]c3ccccc23)C1=O CHEMBL404232 IC50 35.0 nM
Cn1c(-c2cccs2)c(Cl)c2cc(C#N)c(C#N)cc21 CHEMBL3398524 IC50 35.0 nM
Cc1nccc2c1[nH]c1cc(OCc3ccncc3)ccc12 CHEMBL1645553 Ki 35.4 nM
Cn1c(=O)c2c(nc(OCc3cccc(Cl)c3)n2C)n(C)c1=O CHEMBL602260 Ki 36.0 nM
O=C1CCCc2ccc(OCc3ccc(Cl)cc3)cc21 CHEMBL5191498 IC50 36.0 nM
C#CCN(C)Cc1ccnc2c(O)cccc12 CHEMBL258420 IC50 37.0 nM
N[C@@H]1C[C@@H]1c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3416431 IC50 37.0 nM
C#CCN(C)Cc1ccc(O)c2ncccc12 CHEMBL3291021 IC50 37.0 nM
COc1ccc2c(c1)C(=O)c1cc(-c3cccc(C(F)(F)F)c3)nnc1-2 CHEMBL125520 IC50 38.0 nM
N[C@H]1C[C@@H]1c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3416426 IC50 39.0 nM
O=C1c2ccccc2C(=O)c2c(O)ccc(O)c21 CHEMBL17594 Ki 39.0 nM
COc1cc(O)c2c(=O)c3cccc(O)c3oc2c1 CHEMBL363747 IC50 40.0 nM
Cc1cc(=O)oc2cc(OC3CCCC3=O)ccc12 CHEMBL372943 IC50 40.0 nM
Cc1ccc([C@H]2CC(c3cc(Br)ccc3O)=NN2C(=O)c2ccccc2)cc1 CHEMBL3310015 Ki 40.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccc(-c3ccoc3)cc2)cc1 CHEMBL3780391 IC50 40.0 nM
O=C(NNC(=S)Nc1ccc(Cl)c(Cl)c1)c1ccccc1O CHEMBL4476621 IC50 40.0 nM
Cc1ccc(C2CC(c3ccccc3)=NN2C(=O)Cn2c(=O)oc3ccc(Cl)cc32)cc1 CHEMBL4756249 Ki 40.0 nM
Cc1nccc2c1[nH]c1cc(CO)ccc12 CHEMBL5279996 IC50 40.0 nM
COc1ccc(C(/C=C/c2ccc(C)cc2)=N\NC(=O)c2snnc2C)cc1 CHEMBL3310029 Ki 41.0 nM
O=c1[nH]c2ccc(OCc3cccc(I)c3)cc2c(=O)o1 CHEMBL5220349 IC50 43.0 nM
COc1cc2c3c(c1O)C(=O)c1ccccc1C3=NCC2 CHEMBL1917527 IC50 44.0 nM
COc1ccc(/C=C/C(=N\NC(=O)c2ccc(OC)cc2)c2ccc(Br)cc2)cc1 CHEMBL3310021 Ki 45.0 nM
O=C(/C=C/c1ccc(Cl)cc1)c1ccc2c(c1)OCO2 CHEMBL1288972 IC50 47.0 nM
CCOC(=O)C(C(=O)N/N=C/c1ccc([N+](=O)[O-])cc1)[n+]1ccc2ccccc2c1 CHEMBL5434514 IC50 47.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCN4CCN(c5ccccc5)CC4)cc1c23 CHEMBL5173591 IC50 49.0 nM
C#CCN(C)CC(=C)c1ccc(COc2ccccc2)cc1 CHEMBL3415614 IC50 50.0 nM
C#CCN(C)CC(=C)c1cccc(OCc2cccc(F)c2)c1 CHEMBL3415617 IC50 50.0 nM
C#CCN(C)CC(=C)c1cccc(OCc2ccc(OC)cc2)c1 CHEMBL3415781 IC50 50.0 nM
Cc1c(C#N)c(=O)oc2cc(OCc3ccc(Br)cc3)ccc12 CHEMBL4105601 IC50 50.0 nM
Cc1cc(=O)oc2cc(OCc3ccc(Br)cc3)ccc12 CHEMBL4097867 IC50 50.0 nM
Cc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(C)cc43)C(c3ccccc3)C2)cc1 CHEMBL4762679 Ki 50.0 nM
COc1ccccc1C1=NN(C(=O)Cn2c(=O)oc3ccc(Cl)cc32)C(c2ccccc2Cl)C1 CHEMBL4740793 Ki 50.0 nM
Cn1c(=O)c2c(nc(OCc3cccc(C(F)(F)F)c3)n2C)n(C)c1=O CHEMBL602466 Ki 51.0 nM
COc1cc(O)c2c(=O)c(O)c(-c3ccc(O)cc3)oc2c1 CHEMBL442289 IC50 51.0 nM
CN1C(=N)N(C)/C(=C/c2c[nH]c3c(Br)cccc23)C1=O CHEMBL2058420 IC50 52.0 nM
O=c1[nH]c2ccc(OCc3ccccc3)cc2c(=O)o1 CHEMBL5218579 Ki 52.0 nM
C#CCNC1CCc2c(OC(=O)N(C)C)cccc21 CHEMBL1195259 IC50 53.0 nM
COc1ccccc1N1CCN(CCCOc2cc3c4c(nccc4c2)-c2ccccc2C3=O)CC1 CHEMBL5178171 IC50 54.0 nM
C#CCNCCCN1C(=O)S/C(=C\c2ccc(OCc3ccccc3)cc2)C1=O CHEMBL5219890 IC50 54.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccc(N3CCOCC3)cc2)cc1 CHEMBL3781329 IC50 54.8 nM
COc1ccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1OC CHEMBL1257220 IC50 56.0 nM
Cc1ccc(NC(=O)c2cc(=O)c3cc(/C=C/C(=O)OCCN(C)C)ccc3o2)cc1 CHEMBL4292235 Ki 57.0 nM
O=C1NC(=O)c2cc(OCc3ccc(Br)cc3)ccc21 CHEMBL1813523 Ki 58.0 nM
CC(=O)Nc1ccc2c(c1)Cc1ccccc1-2 CHEMBL311469 IC50 59.0 nM
O=c1[nH]c2ccc(OCc3cccc(Br)c3)cc2c(=O)o1 CHEMBL5220071 IC50 59.0 nM
COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1 CHEMBL243664 Ki 59.2 nM
C#CCCCCOc1ccc2c(C)cc(=O)oc2c1 CHEMBL3121791 IC50 59.9 nM
C#CCN(C)CC(=C)c1ccccc1 CHEMBL3415810 IC50 60.0 nM
COc1cc(C2=NN(S(=O)(=O)c3ccc(C)cc3)C(c3ccccc3)C2)ccc1O CHEMBL3780199 Ki 60.0 nM
CC[C@@H]1Cc2c(C)cc(-c3cncnc3)c(O)c2C(=O)O1 CHEMBL4549753 IC50 60.0 nM
COc1cccc(C2=NN(C(=O)Cn3c(=O)oc4ccccc43)C(c3ccccc3Cl)C2)c1 CHEMBL4754569 Ki 60.0 nM
O=C(Cl)C1=Cc2ccccc2CC1=O CHEMBL123155 Log IC50 60.26 nM
O=C1Nc2ccc(/C=C/c3ccccc3)cc2C1=O CHEMBL466872 Ki 61.0 nM
C/C(=N\NCCCN1C(=O)S/C(=C\c2ccc(OCc3ccccc3)cc2)C1=O)c1ccncc1 CHEMBL5220446 IC50 61.0 nM
Cc1ccc(COc2ccc3[nH]c(=O)oc(=O)c3c2)cc1 CHEMBL5220277 IC50 61.0 nM
CC(=O)Nc1cc2ccc(OCc3cccc(Cl)c3)cc2oc1=O CHEMBL3121862 IC50 62.7 nM
COc1ccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1 CHEMBL1257692 IC50 63.0 nM
C/C(=N\Nc1nc2ccccc2nc1Cc1ccccc1)c1cccs1 CHEMBL1258042 IC50 64.0 nM
C#CCN(C)CC(=C)c1cccc(OC)c1 CHEMBL3415800 IC50 65.0 nM
COc1ccc(C2=NN(C(=O)Cn3c(=O)oc4ccc(Cl)cc43)C(c3ccccc3Cl)C2)cc1 CHEMBL4749487 Ki 65.0 nM
O=c1[nH]c2ccc(OCc3ccc4ccccc4c3)cc2c(=O)o1 CHEMBL5218762 IC50 65.0 nM
CCCCCCOc1ccc2cc(C(=O)OC)c(=O)oc2c1 CHEMBL3121865 IC50 66.1 nM
C#CCCCCOc1ccc2cc(NC(C)=O)c(=O)oc2c1 CHEMBL3121788 IC50 66.8 nM
C#CCN(C)[C@H](C)Cc1ccccc1 CHEMBL972 IC50 67.25 nM
O=C(O)C1=Cc2cc([N+](=O)[O-])ccc2CC1=O CHEMBL123071 Log IC50 67.61 nM
O=C(O)c1cc2cc([N+](=O)[O-])ccc2oc1=O CHEMBL3113638 pIC50 67.61 nM
COc1ccc2cc(/C=N/Nc3nc(-c4cccc([N+](=O)[O-])c4)cs3)ccc2c1 CHEMBL5178375 IC50 68.0 nM
C#CCN1CCC(/C=C\c2cccc(F)c2)CC1 CHEMBL4450588 IC50 68.4 nM
COc1ccc(/C=C/c2coc3cc(OC)ccc3c2=O)cc1 CHEMBL4865494 IC50 69.0 nM
Oc1ccccc1C1CC(c2c3ccccc3cc3ccccc23)=NN1 CHEMBL1760718 Ki 69.91 nM
C[C@]1(N)C[C@@H]1c1ccccc1 CHEMBL3330339 IC50 70.0 nM
CN(C)c1ccc2nc3ccc(=[N+](C)C)cc-3sc2c1 CHEMBL191083 IC50 70.0 nM
N[C@H]1C[C@H]1c1cccc(NC(=O)c2ccccc2)c1 CHEMBL3416434 IC50 70.0 nM
CN(C)c1ccc2nc3ccc(N(C)C)cc3[s+]c2c1 CHEMBL405110 IC50 70.0 nM
C#CCN(C)C[C@@H](O)COc1cc(N)c(Cl)cc1Cl CHEMBL5423380 IC50 71.5 nM
C#CCN(C)C[C@H](O)COc1cc(N)c(Cl)cc1Cl CHEMBL5437624 IC50 71.5 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc1c23 CHEMBL5206039 IC50 72.0 nM
COc1ccc2cc(/C=N/Nc3nc(-c4ccccc4)c(C)s3)ccc2c1 CHEMBL5176924 IC50 72.0 nM
Cc1ccsc1/C=N/Nc1nc2ccccc2nc1Cc1ccccc1 CHEMBL1258387 IC50 74.0 nM
COC(=O)c1cc2ccc(OCCc3ccc(Cl)cc3)cc2oc1=O CHEMBL3121795 IC50 74.8 nM
CCSc1ccc(C[C@H](C)N)cc1 CHEMBL387777 Ki 75.0 nM
Clc1ccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1 CHEMBL1257570 IC50 76.0 nM
COC(=O)c1cc2ccc(OCc3cccc(F)c3)cc2oc1=O CHEMBL3121793 IC50 77.2 nM
C/C(=N\Nc1nc2ccccc2nc1Cc1ccccc1)c1ccccc1 CHEMBL1257693 IC50 79.0 nM
C#CCN(C)CCc1ccc(O)c2ncccc12 CHEMBL3687959 IC50 80.0 nM
COc1cc(C2=NNC(c3ccc(Cl)cc3)C2)ccc1O CHEMBL4289477 Ki 80.0 nM
C(=N/Nc1nc2ccccc2nc1Cc1ccccc1)\c1ccccc1 CHEMBL1257452 IC50 81.0 nM
C(=N/NC1Nc2ccccc2N=C1Cc1ccccc1)\c1ccccc1 CHEMBL4875623 IC50 81.0 nM
Oc1ccc(C2CC(c3c4ccccc4cc4ccccc34)=NN2)c(O)c1 CHEMBL1760719 Ki 81.54 nM
c1ccc(Cc2nc3ccccc3n3c(-c4ccccc4)nnc23)cc1 CHEMBL1258388 IC50 82.0 nM
N[C@@]1(c2ccccc2)C[C@H]1c1ccccc1 CHEMBL3330331 IC50 82.8 nM
COc1ccccc1/C=N/Nc1nc2ccccc2nc1Cc1ccccc1 CHEMBL1257219 IC50 83.0 nM
CN(C)c1ccc(/C=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1 CHEMBL1257933 IC50 83.0 nM
O=c1[nH]c2ccc(OCc3cccc(C(F)(F)F)c3)cc2c(=O)o1 CHEMBL5220869 IC50 83.0 nM
C/N=C1\N(C)C(=O)/C(=C\c2c[nH]c3ccc(Br)cc23)N1C CHEMBL2058427 IC50 85.0 nM
N[C@@H]1C[C@H]1c1ccccc1 CHEMBL1179 IC50 85.0 nM
C/C(=N\Nc1nc2ccccc2nc1Cc1ccccc1)c1ccc(C)cc1 CHEMBL1258159 IC50 86.0 nM
C=NNc1nc2ccccc2nc1Cc1ccccc1 CHEMBL1256152 IC50 86.0 nM
O=C1c2ccccc2-c2nccc3cc(OCCCCCN4CCN(c5ccccc5Cl)CC4)cc1c23 CHEMBL5198200 IC50 86.0 nM
O=C(c1ccccc1)c1nc2ccccc2n2c(-c3ccccc3Cl)nnc12 CHEMBL1258499 IC50 88.0 nM
COc1ccc(/C(C)=N/Nc2nc3ccccc3nc2Cc2ccccc2)cc1 CHEMBL1257451 IC50 89.0 nM
COc1ccc(NC(=S)N2N=C(c3ccccc3)CC2c2ccc(O)cc2)cc1 CHEMBL1796449 Ki 90.0 nM
N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(N3CCOC3=O)c2)cc1 CHEMBL3780374 IC50 90.5 nM
C/C(=N\Nc1nc2ccccc2nc1Cc1ccccc1)c1ccccn1 CHEMBL1258041 IC50 91.0 nM
COc1ccc(/C=C/C(=N\NC(=O)c2ccco2)c2ccc(Br)cc2)cc1 CHEMBL3310022 Ki 91.0 nM
COc1ccccc1N1CCN(CCCCOc2cc3c4c(nccc4c2)-c2ccccc2C3=O)CC1 CHEMBL5191497 IC50 91.0 nM
C#CCNCCCN1C(=O)S/C(=C/c2ccc([N+](=O)[O-])cc2)C1=O CHEMBL5219309 IC50 93.0 nM
N[C@@]1(c2ccccc2)C[C@@H]1c1ccccc1 CHEMBL3330341 IC50 94.0 nM
COc1cccc(COc2ccc3[nH]c(=O)oc(=O)c3c2)c1 CHEMBL5219611 IC50 94.0 nM
O=c1ccoc2ccc(OCc3ccc(Br)cc3)cc12 CHEMBL1945155 IC50 95.0 nM
CCN(CC)Cc1ccc(/C=C2\Cc3ccc(OC)cc3C2=O)cc1 CHEMBL5183930 IC50 95.0 nM
O=C(/C=C/c1ccc(F)cc1)c1ccc2c(c1)OCCO2 CHEMBL5273404 IC50 95.0 nM
O=[N+]([O-])c1ccc(-c2csc(N/N=C(/CSc3nc4ccccc4s3)c3ccccc3)n2)cc1 CHEMBL5433240 IC50 95.0 nM
C/N=C1\N(C)C(=O)/C(=C\c2c[nH]c3ccccc23)N1C CHEMBL512332 IC50 98.0 nM