Nc1ccc(-c2cnc3[nH]nc(C(=O)c4c(F)ccc(NS(=O)(=O)Cc5ccccc5)c4F)c3c2)cc1 CHEMBL4865410 Kd 1.5 nM
NS(=O)(=O)c1ccc(-c2cnc3[nH]nc(C(=O)c4c(F)ccc(NS(=O)(=O)Cc5ccccc5)c4F)c3c2)cc1 CHEMBL4798975 Kd 1.7 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 3.8 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(=O)(=O)NC(C)=O)cc4)cc23)c1F CHEMBL4790247 IC50 29.0 nM
O=C(O)c1ccc(-c2n[nH]c3cc(F)ccc23)cc1 CHEMBL4758063 IC50 41.0 nM
NS(=O)(=O)c1ccc(-c2n[nH]c3cc(F)ccc23)cc1 CHEMBL4879048 IC50 61.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 70.0 nM
NC(=O)c1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4866649 IC50 83.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4)cc23)c1F CHEMBL4784779 IC50 89.0 nM
O=C(O)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4848865 IC50 96.0 nM
CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(c3c2)-c2cn(nc2C(F)(F)F)CCCC1=O CHEMBL5086263 IC50 132.0 nM
C[C@@H](NC(=O)c1ncnc(N)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1 CHEMBL3348923 Kd apparent 146.0 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 150.0 nM
CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(c3c2)-c2cn(nc2C(F)(F)F)CCCC1=O CHEMBL5093741 IC50 173.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F CHEMBL1230020 Kd 190.0 nM
O=C(O)c1ccc(-c2n[nH]c3ccccc23)cc1 CHEMBL4748767 IC50 190.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 200.0 nM
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 CHEMBL1908397 Kd 250.0 nM
N#C/C(=C/c1cccc(-c2ncnc3[nH]ccc23)c1)C(N)=O CHEMBL5278864 IC50 281.0 nM
CS(=O)(=O)c1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4865159 IC50 290.0 nM
Fc1ccc2c(-c3ccccc3)n[nH]c2c1 CHEMBL4849172 IC50 310.0 nM
O=S(=O)(Nc1ccccc1)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4872723 IC50 310.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 330.0 nM
O=S(=O)(NC1CC1)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4858450 IC50 380.0 nM
CS(=O)(=O)CCCOc1cccc2c1ccn2-c1ccnc(N[C@H]2CC[C@H](C(=O)N3CCC(O)CC3)CC2)n1 CHEMBL2425628 Kd 390.0 nM
COc1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4846360 IC50 390.0 nM
O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 CHEMBL44 IC50 400.0 nM
COc1ccccc1NS(=O)(=O)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4874017 IC50 420.0 nM
O=S(=O)(Nc1cccnc1)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4871499 IC50 450.0 nM
N#Cc1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4854291 IC50 470.0 nM
CS(=O)(=O)Nc1ccc(-c2n[nH]c3cc(F)ccc23)cc1 CHEMBL4860404 IC50 480.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(N)cc4)cc23)c1F CHEMBL4785015 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4cccc(N)c4)cc23)c1F CHEMBL4797449 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4cccc(O)c4)cc23)c1F CHEMBL4796882 IC50 500.0 nM
CCCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4)cc23)c1F CHEMBL4797480 IC50 500.0 nM
CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4C)cc23)c1F CHEMBL4779231 IC50 500.0 nM
CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4cnc(C(F)(F)F)nc4)cc23)c1F CHEMBL4783187 IC50 500.0 nM
O=C(c1ccc(F)c(NS(=O)(=O)Cc2ccccc2)c1F)c1n[nH]c2ncc(-c3ccc(C4N=NN=N4)cc3)cc12 CHEMBL4781930 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccccc4Cl)cc23)c1F CHEMBL4783282 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccccc4OC)cc23)c1F CHEMBL4789177 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccccc4O)cc23)c1F CHEMBL4797354 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(C)(=O)=O)cc4)cc23)c1F CHEMBL4798539 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(F)cc4)cc23)c1F CHEMBL4776558 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4cccc([N+](=O)[O-])c4)cc23)c1F CHEMBL4781410 IC50 500.0 nM
CS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4)cc23)c1F CHEMBL4777904 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(NS(C)(=O)=O)cc4)cc23)c1F CHEMBL4782205 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(C(=O)NCC(O)CO)cc4)cc23)c1F CHEMBL4793605 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)c(F)c4)cc23)c1F CHEMBL4799858 IC50 500.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)c(C)c4)cc23)c1F CHEMBL4795514 IC50 500.0 nM
NS(=O)(=O)c1ccc(-c2cnc3[nH]nc(C(=O)c4c(F)ccc(NS(=O)(=O)Nc5ccccc5)c4F)c3c2)cc1 CHEMBL4781760 IC50 500.0 nM
NS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4)cc23)c1F CHEMBL4782658 IC50 500.0 nM
CCNS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4)cc23)c1F CHEMBL4786436 IC50 500.0 nM
CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4ccc(C(C)C)cc4)cc23)c1F CHEMBL4782457 IC50 500.0 nM
CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4ccc(Cl)cc4C)cc23)c1F CHEMBL4786277 IC50 500.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 Kd 590.0 nM
O=C(c1ccc(-c2n[nH]c3cc(F)ccc23)cc1)C(F)(F)F CHEMBL4847040 IC50 600.0 nM
NS(=O)(=O)c1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4866764 IC50 620.0 nM
Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F CHEMBL191003 Kd 630.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 700.0 nM
O=S(=O)(Nc1ccc(-c2n[nH]c3cc(F)ccc23)cc1)c1cccnc1 CHEMBL4875241 IC50 750.0 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 Kd 810.0 nM
CNc1ncc2cc(-c3ccc(-c4ncccc4F)cc3Cl)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1 CHEMBL5090394 IC50 830.0 nM
O=S(=O)(NC1CCCCC1)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4874062 IC50 860.0 nM
CC(=O)c1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4875545 IC50 860.0 nM
O=S(=O)(Nc1ccc(F)cc1)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4850634 IC50 880.0 nM
CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)nc2[nH]ccc12 CHEMBL464552 Kd 910.0 nM
O[C@H]1CC[C@H](c2n[nH]cc2-c2ccnc(NC3CCCC3)n2)CC1 CHEMBL507249 IC50 920.0 nM
CN(C)C[C@@H]1CCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCO1 CHEMBL91829 Kd 930.0 nM
N#CCc1cnc(-c2ccc3ccccc3c2)n1-c1ccnc(N[C@H]2CCCN(C(=O)C3CC3)C2)n1 CHEMBL5396715 IC50 970.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccccc4)cc23)c1F CHEMBL4800472 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F CHEMBL4791205 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(F)cc4C)cc23)c1F CHEMBL4797964 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(OC)cc4Cl)cc23)c1F CHEMBL4794368 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccccc4C)cc23)c1F CHEMBL4781671 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4cccc(OC)c4)cc23)c1F CHEMBL4797810 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(O)cc4)cc23)c1F CHEMBL4792739 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccccc4F)cc23)c1F CHEMBL4783920 IC50 1000.0 nM
CCCCS(=O)(=O)Nc1cccc(C(=O)c2n[nH]c3ncc(-c4ccc(OC)cc4Cl)cc23)c1F CHEMBL4793390 IC50 1000.0 nM
CCCCS(=O)(=O)Nc1cccc(C(=O)c2n[nH]c3ncc(-c4ccc(F)cc4C)cc23)c1F CHEMBL4779611 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(C(N)=O)cc4)cc23)c1F CHEMBL4797274 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(=O)(=O)NCC(O)CO)cc4)cc23)c1F CHEMBL4784132 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(S(N)(=O)=O)cc4F)cc23)c1F CHEMBL4793405 IC50 1000.0 nM
CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4ccc(F)cc4C)cc23)c1F CHEMBL4780791 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(N(C)C)cc4)cc23)c1F CHEMBL4791513 IC50 1000.0 nM
COc1ccc(-c2cnc3[nH]nc(C(=O)c4cccc(NS(C)(=O)=O)c4F)c3c2)c(Cl)c1 CHEMBL4790081 IC50 1000.0 nM
Cc1cc(F)ccc1-c1cnc2[nH]nc(C(=O)c3cccc(NS(C)(=O)=O)c3F)c2c1 CHEMBL4798130 IC50 1000.0 nM
CS(=O)(=O)Nc1cccc(C(=O)c2n[nH]c3ncc(-c4ccc5c(c4)OCCO5)cc23)c1F CHEMBL4777264 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(C(=O)O)cc4)cc23)c1F CHEMBL4776399 IC50 1000.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2n[nH]c3ncc(-c4ccc(-c5nnn[nH]5)cc4)cc23)c1F CHEMBL4779020 IC50 1000.0 nM
CCCS(=O)(=O)Nc1c(F)ccc(C(=O)c2n[nH]c3ncc(-c4ccc(C5N=NN=N5)cc4)cc23)c1F CHEMBL4780999 IC50 1000.0 nM