C#CCNC(=O)c1cc(NC(=O)C=C)cc(-c2n[nH]c3ccccc23)c1 CHEMBL4764965 IC50 0.6 nM
O=C(O)c1cccc(NC2=CC(=O)c3ccccc3C2=O)c1 CHEMBL3329977 IC50 1.9 nM
C=CC(=O)N1CCC[C@@H](n2nc(-c3cn(CC(F)(F)c4ccc(Cl)cc4)nn3)c3c(N)ncnc32)C1 CHEMBL5174214 IC50 3.0 nM
C=CC(=O)N1CCC[C@@H](n2nc(-c3cn(CC(F)(F)c4ccccc4)nn3)c3c(N)ncnc32)C1 CHEMBL5195838 IC50 4.0 nM
C=CC(=O)Nc1cccc(-c2n[nH]c3cc(C)ccc23)c1 CHEMBL4749823 IC50 5.0 nM
C=CC(=O)Nc1cccc(-c2n[nH]c3ccccc23)c1 CHEMBL3901151 IC50 6.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCc3ccccc3)ncn2)c1 CHEMBL5284723 IC50 10.0 nM
C=CC(=O)Nc1cccc(-c2n[nH]c3cc([N+](=O)[O-])ccc23)c1 CHEMBL4787266 IC50 14.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 27.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 30.0 nM
C#Cc1nn([C@@H]2CCCN(C(=O)C=C)C2)c2ncnc(N)c12 CHEMBL4071151 IC50 30.0 nM
C=CC(=O)Nc1cc(C(=O)NCc2cn([C@@H]3CCCC[C@H]3OC)nn2)cc(-c2n[nH]c3ccccc23)c1 CHEMBL5169325 IC50 30.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCc3ccc(F)c(F)c3)ncn2)c1 CHEMBL5283781 IC50 42.0 nM
CNc1cc(Oc2cccc(NC(=O)CCl)c2)ncn1 CHEMBL5271442 IC50 60.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCCc3ccc(Cl)cc3)ncn2)c1 CHEMBL5267499 IC50 66.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCc3cc(F)cc(F)c3)ncn2)c1 CHEMBL5279577 IC50 74.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 80.0 nM
NC(=O)c1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4866649 IC50 96.0 nM
C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 CHEMBL31965 Kd 110.0 nM
CN(Cc1ccccc1)c1cc(Oc2cccc(NC(=O)CCl)c2)ncn1 CHEMBL5271266 IC50 110.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCc3c(F)ccc(F)c3F)ncn2)c1 CHEMBL5267684 IC50 110.0 nM
C=CS(=O)(=O)N1CCC[C@@H]1Cn1cc(-c2ccc3c(c2)OCO3)c2c(N)ncnc21 CHEMBL4095253 IC50 188.6 nM
O=C(O)CCSC1=CC(=O)c2ccccc2C1=O CHEMBL100206 Kd 230.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCCc3c[nH]c4ccccc34)ncn2)c1 CHEMBL5282673 IC50 260.0 nM
COc1ccc(CNc2cc(Oc3cccc(NC(=O)CCl)c3)ncn2)cc1OC CHEMBL5277855 IC50 260.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NC3CCCC3)ncn2)c1 CHEMBL5271906 IC50 270.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 293.0 nM
COc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL1077979 IC50 300.0 nM
COc1ccc(CNc2cc(Oc3cccc(NC(=O)CCl)c3)ncn2)cc1 CHEMBL5272546 IC50 300.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCc3ccc(F)cc3F)ncn2)c1 CHEMBL5271334 IC50 360.0 nM
Cc1ccc(CNc2cc(Oc3cccc(NC(=O)CCl)c3)ncn2)cc1 CHEMBL5271519 IC50 360.0 nM
O=C(CCl)Nc1cccc(Oc2cc(NCc3ccc(C(F)(F)F)cc3)ncn2)c1 CHEMBL5273066 IC50 410.0 nM
C=CC(=O)Nc1cccc(Oc2cc(NC)ncn2)c1 CHEMBL5273762 IC50 420.0 nM
CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C CHEMBL180022 Kd 530.0 nM
NS(=O)(=O)c1ccc(-c2n[nH]c3cc(F)ccc23)cc1 CHEMBL4879048 IC50 540.0 nM
COc1ccccc1CNc1cc(Oc2cccc(NC(=O)CCl)c2)ncn1 CHEMBL5266940 IC50 800.0 nM
O=S(=O)(Nc1ccccc1)c1cccc(-c2n[nH]c3cc(F)ccc23)c1 CHEMBL4872723 IC50 840.0 nM
O[C@H]1CC[C@H](c2n[nH]cc2-c2ccnc(NC3CCCC3)n2)CC1 CHEMBL507249 IC50 860.0 nM
O=C(CCl)Nc1cccc(Oc2cc(N3CCOCC3)ncn2)c1 CHEMBL5287907 IC50 900.0 nM
CS(=O)(=O)c1ccc(NS(=O)(=O)c2cccc(-c3n[nH]c4cc(F)ccc34)c2)cc1 CHEMBL4865159 IC50 920.0 nM
COc1ccc(CCNc2cc(Oc3cccc(NC(=O)CCl)c3)ncn2)cc1 CHEMBL5278028 IC50 930.0 nM
NCc1ccc2[nH]c3nc(N)nc(N4CCCCC4)c3c2c1 CHEMBL3715933 IC50 1000.0 nM
COc1cc2[nH]c3nc(N)nc(N4CCOCC4)c3c2cc1OC CHEMBL3715441 IC50 1000.0 nM
COc1cc2[nH]c3nc(N)nc(N4CCCCC4)c3c2cc1OC CHEMBL3717892 IC50 1000.0 nM
Nc1nc(N2CCNCC2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3718826 IC50 1000.0 nM
Nc1nc(N2CCC(Cc3ccccc3)CC2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3715822 IC50 1000.0 nM
Nc1nc(N2CCCCC2)c2c(n1)[nH]c1ccc(Cl)cc12 CHEMBL3714913 IC50 1000.0 nM
Nc1nc(N2CCC(C(=O)O)CC2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3719327 IC50 1000.0 nM
CC1CC(C)CN(c2ncnc3[nH]c4ccc(O)cc4c23)C1 CHEMBL3714792 IC50 1000.0 nM
O=C(O)CCCCCN1CCN(c2ncnc3[nH]c4ccc(O)cc4c23)CC1 CHEMBL3716342 IC50 1000.0 nM
Cc1nc(N2CCOCC2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3718455 IC50 1000.0 nM
Cc1nc(N2CCCC(C)C2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3719173 IC50 1000.0 nM
CNc1nc(C)nc2[nH]c3ccc(O)cc3c12 CHEMBL3715283 IC50 1000.0 nM
Cc1nc(N2CCCC2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3718879 IC50 1000.0 nM
CCN(CC)c1nc(C)nc2[nH]c3ccc(O)cc3c12 CHEMBL3718605 IC50 1000.0 nM
Cc1nc(NCCO)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3718009 IC50 1000.0 nM
Cc1nc(N2CCC(CO)CC2)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3716916 IC50 1000.0 nM
Cc1nc(N2CCCCC2CO)c2c(n1)[nH]c1ccc(O)cc12 CHEMBL3717442 IC50 1000.0 nM
CN(C)c1ccc(-c2ncnc3[nH]c4ccc(C(N)=O)cc4c23)cc1 CHEMBL3716854 IC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM