COc1cc(C)c(S(N)(=O)=O)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4283739 IC50 0.1 nM
CCS(=O)(=O)Nc1ccc(OC)c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)c1 CHEMBL4290518 IC50 0.32 nM
COc1cc(C)c(C(N)=O)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4294318 IC50 0.42 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 0.69 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCCCC3)cn2)cs1)C(F)(F)F CHEMBL3683270 IC50 0.7 nM
CC(n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCCCC3)cn2)cs1)C(F)(F)F CHEMBL4083562 IC50 0.7 nM
COc1ccc(C(N)=O)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4282644 IC50 1.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2C2(C(F)(F)F)CC2)n1 CHEMBL4868362 IC50 1.0 nM
O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCOCC2)cn1 CHEMBL3683259 IC50 1.44 nM
COc1ccc(S(N)(=O)=O)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4278211 IC50 1.5 nM
CC1(O)CN(c2cnc(C(=O)Nc3csc(-c4nncn4C4CC4)n3)cc2-n2cnc(C3CC3)c2)C1 CHEMBL3683260 IC50 1.58 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC(C)(O)C3)cn2)cs1)C(F)(F)F CHEMBL3683262 IC50 1.69 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCC3)cn2)cs1)C(F)(F)F CHEMBL3683265 IC50 1.7 nM
O=C(Nc1cccc(-c2nncn2C2CC2)n1)c1cc(-c2cnn(C3CC3)c2)cn(Cc2ccccc2F)c1=O CHEMBL5424950 IC50 1.73 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCC(C)(O)CC3)cn2)cs1)C(F)(F)F CHEMBL3687971 IC50 1.8 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N(C)C)cn2)cs1)C(F)(F)F CHEMBL3683263 IC50 1.88 nM
O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCCC2)cn1 CHEMBL3683267 IC50 1.9 nM
COc1nn(-c2cncc(N(C)C)c2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4634900 IC50 1.9 nM
CCn1cc(Br)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3937743 IC50 2.0 nM
C[C@](O)(CO)c1ccc(C(=O)Nc2cc3c(cn2)c(Br)cn3C2CC2)cc1 CHEMBL3644048 IC50 2.0 nM
O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCCCC2)cn1 CHEMBL3639821 IC50 2.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)C2CN(C)CCO2)n1 CHEMBL4743649 IC50 2.0 nM
Cc1cc(F)c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)cc1-n1cnc(C2CC2)c1 CHEMBL3916717 EC50 2.0 nM
CCn1cc(C(=O)Nc2cccc(-c3nncn3[C@@H](C)C(F)(F)F)n2)c(OC)n1 CHEMBL4857751 IC50 2.0 nM
COc1nn(CC2CC2)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4871543 IC50 2.0 nM
COCCn1cc(C(=O)Nc2cccc(-c3nncn3[C@@H](C)C(F)(F)F)n2)c(OC)n1 CHEMBL4850048 IC50 2.0 nM
C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3cccnc23)n1)C(F)(F)F CHEMBL4875364 IC50 2.0 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(C)CC3)cn2)cs1)C(F)(F)F CHEMBL3687973 IC50 2.1 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCCC3)cn2)cs1)C(F)(F)F CHEMBL3683266 IC50 2.2 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCC(O)C3)cn2)cs1)C(F)(F)F CHEMBL3683269 IC50 2.2 nM
O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCC2)cn1 CHEMBL3683264 IC50 2.4 nM
CNC(=O)c1ccc(OC)c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)c1 CHEMBL4279174 IC50 2.4 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2cncn2C(C)C)n1 CHEMBL4641666 IC50 2.4 nM
CC1(O)CCN(c2cnc(C(=O)Nc3csc(-c4nncn4C4CC4)n3)cc2-n2cnc(C3CC3)c2)CC1 CHEMBL3687972 IC50 2.5 nM
C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCOCC3)cn2)cs1)C(F)(F)F CHEMBL3683261 IC50 2.62 nM
O=C(Nc1cccc(-c2nncn2C2CC2)c1)c1cc(-n2cnc(C3CC3)c2)ccn1 CHEMBL4783726 IC50 2.87 nM
CC(C)(O)c1ccc(C(=O)Nc2cc3c(cn2)c(Br)cn3CC2CC2)cc1 CHEMBL3644036 IC50 3.0 nM
CCn1cc(Br)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 CHEMBL3644037 IC50 3.0 nM
O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCC(O)C2)cn1 CHEMBL3683268 IC50 3.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4860819 IC50 3.0 nM
COc1nn(CC(F)(F)F)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4862258 IC50 3.0 nM
COc1nn(-c2cnccn2)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4866921 IC50 3.0 nM
COc1nn(-c2cccnn2)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4862847 IC50 3.0 nM
COc1ccccc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4861953 IC50 3.0 nM
C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3nccnc23)n1)C(F)(F)F CHEMBL4877113 IC50 3.0 nM
COc1ncc(C)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4853505 IC50 3.0 nM
CN1CCN(c2cnc(C(=O)Nc3csc(-c4nncn4C4CC4)n3)cc2-n2cnc(C3CC3)c2)CC1 CHEMBL3687974 IC50 3.1 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4643577 IC50 3.9 nM
C[C@](O)(CO)c1ccc(C(=O)Nc2cc3c(cn2)c(Cl)cn3C2CC2)cc1 CHEMBL3644049 IC50 4.0 nM
COc1cc(C)c(S(C)(=O)=O)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4289040 IC50 4.0 nM
C[C@H]1CCCOc2ccccc2C(=O)Nc2cccc(n2)-c2nncn21 CHEMBL4514925 IC50 4.0 nM
Cc1cn(-c2ccc3c(c2)C(=O)Nc2cccc(n2)-c2nncn2CCCCO3)cn1 CHEMBL4569388 IC50 4.0 nM
CCn1cc(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)c(OC)n1 CHEMBL4640063 IC50 4.1 nM
Cc1cc(F)c(C(=O)Nc2cccc(-c3nncn3[C@@H](C)C(F)(F)F)n2)cc1-n1cnc(C2CC2)c1 CHEMBL4855907 IC50 4.3 nM
Cn1cc(Br)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 CHEMBL3644041 IC50 5.0 nM
COc1ccc(S(C)(=O)=O)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4287097 IC50 5.0 nM
Cn1cc(-c2ccc3c(c2)C(=O)Nc2cccc(n2)-c2nncn2CCCCO3)cn1 CHEMBL4475667 IC50 5.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2[C@@H]2CCOC2)n1 CHEMBL4860731 IC50 5.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2C2CCC2(F)F)n1 CHEMBL4876558 IC50 5.0 nM
CC(C)Oc1ccc2c(c1)C(=O)N(c1cccc(-c3nncn3[C@H](C)CO)n1)C2 CHEMBL3954836 pIC50 5.012 nM
COc1nn(-c2cccnc2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4633993 IC50 5.3 nM
COc1nn(-c2cncc(C3CC3)c2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4642251 IC50 5.6 nM
CCn1cc(Cl)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3955000 IC50 6.0 nM
CN(C)CCn1cc(-c2ccc3c(c2)C(=O)Nc2cccc(n2)-c2nncn2CCCCO3)cn1 CHEMBL4456722 IC50 6.0 nM
COc1cc2nncc(Oc3ccc(NC(=O)c4cn(C(C)C)c5ccccc5c4=O)cc3)c2cc1OC CHEMBL4466569 IC50 6.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)F)n1 CHEMBL4878163 IC50 6.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c5ccccc5c4=O)cc3)c2cc1OC CHEMBL4449840 IC50 6.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-c4cn[nH]c4)ccc3n2)cc1 CHEMBL3330167 IC50 6.3 nM
CN[C@@H]1CC2OC([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL3683258 IC50 6.3 nM
CC(C)n1cnnc1-c1cccc(N2Cc3ccc(OC[C@@H]4CN(C)CCO4)cc3C2=O)n1 CHEMBL3946139 pEC50 6.31 nM
C[C@H]1CCCOc2nn(C)cc2C(=O)Nc2cccc(n2)-c2nncn21 CHEMBL4646085 IC50 6.8 nM
COc1nn(CC2CC2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4647065 IC50 6.9 nM
CCn1cc(C)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 CHEMBL3644038 IC50 7.0 nM
Cn1cc(Br)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3916273 IC50 7.0 nM
C[C@H]1CCCOc2cc(F)ccc2C(=O)Nc2cccc(n2)-c2nncn21 CHEMBL4562269 IC50 7.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2C(C)CO)n1 CHEMBL4865259 IC50 7.0 nM
C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3c2OCCN3C)n1)C(F)(F)F CHEMBL4874460 IC50 7.0 nM
COc1ncccc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4852061 IC50 7.0 nM
COc1ncc(F)cc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4849014 IC50 7.0 nM
COCCn1cc(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)c(OC)n1 CHEMBL4641264 IC50 7.3 nM
NC[C@H](Oc1cnc(-c2ccoc2)c(-c2c[nH]c3ncccc23)c1)c1ccccc1 CHEMBL3330168 IC50 7.9 nM
COCCOc1ccc2c(c1)C(=O)N(c1cccc(-c3nncn3[C@H](C)CO)n1)C2 CHEMBL3975466 pIC50 7.943 nM
COCCOc1ccc2c(c1)C(=O)N(c1cccc(-c3nncn3C(C)C)n1)C2 CHEMBL3966978 pIC50 7.943 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2cc(F)ccc21 CHEMBL4590290 IC50 8.0 nM
C[C@@H]1CCOc2cc(F)ccc2C(=O)Nc2cccc(n2)-c2nncn2C1 CHEMBL4542440 IC50 8.0 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(N3CCOCC3)cc21 CHEMBL4548492 IC50 8.0 nM
CS(=O)(=O)c1ccc2c(c1)C(=O)Nc1cccc(n1)-c1nncn1CCCCO2 CHEMBL4473364 IC50 8.0 nM
C[C@@H]1CCOc2cc(F)c(-c3cnn(CCN(C)C)c3)cc2C(=O)Nc2cccc(n2)-c2nncn2C1 CHEMBL4591648 IC50 8.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2[C@H]2CCOC2)n1 CHEMBL4848618 IC50 8.0 nM
CCn1cc(Cl)c2cnc(NC(=O)c3ccc([C@](C)(O)CO)cc3)cc21 CHEMBL3963789 IC50 9.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2C(C)C(F)(F)F)n1 CHEMBL4857053 IC50 9.0 nM
CC(C)n1cc(-c2cc(C(=O)Nc3cccc(-c4nncn4C4CC4)n3)c(=O)n(Cc3ccccc3F)c2)cn1 CHEMBL5400071 IC50 9.13 nM
C[C@H](CO)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3962015 pIC50 10.0 nM
Cn1cc(Cl)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 CHEMBL3644050 IC50 11.0 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccccc21 CHEMBL4561768 IC50 11.0 nM
CC(CF)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3925645 pIC50 12.59 nM
CC(C)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3952214 pIC50 12.59 nM
Cc1cc(F)c(C(=O)Nc2cccc(-c3nncn3C(C)C)c2)cc1-n1cnc(C2CC2)c1 CHEMBL5427887 IC50 12.9 nM
C[C@@H]1CCn2cnnc2-c2cccc(n2)NC(=O)c2ccccc2OC1 CHEMBL4442116 IC50 13.0 nM
O=C(Nc1nc2cc(C(F)(F)F)cc(NC3CC3)n2n1)c1cccnc1 CHEMBL3330170 IC50 13.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-n4ccnc4)ccc3n2)cc1 CHEMBL1642655 IC50 14.0 nM
CCn1cc(C)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3910870 IC50 14.0 nM
C[C@@H]1CCOc2ccccc2C(=O)Nc2cccc(n2)-c2nncn2C1 CHEMBL4462230 IC50 14.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-n4ccnc4)ccc3n2)cc1 CHEMBL4778541 IC50 14.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3c(ccc4ccccc43)n2)cc1 CHEMBL1642656 IC50 15.0 nM
CC(C)Oc1ccc2c(c1)C(=O)N(c1cccc(-c3nncn3C(C)C)n1)C2 CHEMBL3937245 pIC50 15.85 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1 CHEMBL2205628 IC50 16.0 nM
CC(C)(CO)c1ccc(C(=O)Nc2cc3c(cn2)c(Cl)cn3C2CC2)cc1 CHEMBL3644053 IC50 16.0 nM
COc1nn(-c2cncnc2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4638598 IC50 16.0 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(F)cc21 CHEMBL4469413 IC50 17.0 nM
COc1nn(-c2ccccn2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4642504 IC50 17.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)[C@H]2CN(c3ccc(C4CC4)nc3)CCO2)n1 CHEMBL4744428 IC50 17.0 nM
COc1ncncc1C(=O)Nc1cccc(-c2nncn2[C@@H](C)C(F)(F)F)n1 CHEMBL4862220 IC50 17.0 nM
C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccn(C)c2=O)n1)C(F)(F)F CHEMBL4873779 IC50 18.0 nM
CC(C)(C(=O)O)c1ccc(C(=O)Nc2cn3cc(-c4ccsc4)ccc3n2)cc1 CHEMBL1642657 IC50 19.0 nM
Cc1cn(C)c2cc(NC(=O)c3ccc(C(C)(C)O)cc3)ncc12 CHEMBL3644045 IC50 19.0 nM
Cn1cc(Cl)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3966379 IC50 19.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)CCC(=O)N3)n1 CHEMBL5417817 IC50 19.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(-c4cnn(C)c4)cccc3[nH]2)n1 CHEMBL4870142 IC50 19.6 nM
CCS(=O)(=O)Nc1cccc(-c2n[nH]c3ccc(-c4nncn4C(C)C)cc23)c1 CHEMBL4860629 IC50 19.8 nM
CC(CC#N)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3928256 pIC50 19.95 nM
CC[C@H](C)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3943495 pIC50 19.95 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCCOc2ccccc21 CHEMBL4447729 IC50 20.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2C2CC(F)(F)C2)n1 CHEMBL4860716 IC50 20.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-c4cccnc4)ccc3n2)cc1 CHEMBL2205633 IC50 21.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(Br)ccc3n2)cc1 CHEMBL2205629 IC50 21.0 nM
COc1nn(-c2cnccn2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4632672 IC50 21.0 nM
Cc1ccc2nc(NC(=O)c3ccc(C(C)(C)C)cc3)cn2c1 CHEMBL2205626 IC50 22.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3cccc(-c4ccncc4)c3[nH]2)n1 CHEMBL4845717 IC50 23.1 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)OCC(=O)N3C)n1 CHEMBL5437227 IC50 26.0 nM
COCn1cc(-c2cccc(-c3n[nH]c4ccc(-c5nncn5C(C)C)cc34)c2)cn1 CHEMBL4866123 IC50 26.9 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(N3CC4(COC4)C3)cc21 CHEMBL4544934 IC50 28.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2ccn(C)n2)n1 CHEMBL4647622 IC50 29.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)CCC(=O)N3C)n1 CHEMBL5411752 IC50 29.0 nM
CCOC(C)n1cc(-c2cccc(-c3n[nH]c4ccc(-c5nncn5C(C)C)cc34)c2)cn1 CHEMBL4855899 IC50 29.9 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-n4cccc4)ccc3n2)cc1 CHEMBL2205634 IC50 30.0 nM
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(Br)cc21 CHEMBL4590759 IC50 31.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)C2CN(c3cccnc3)CCO2)n1 CHEMBL4753983 IC50 31.0 nM
COC[C@@H](C)n1cnnc1-c1cccc(NC(=O)c2cn(C)nc2OC)n1 CHEMBL4867144 IC50 31.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)OCc2cncn2-3)n1 CHEMBL5431768 IC50 31.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3cc(-c4cn[nH]c4)ccc3[nH]2)n1 CHEMBL4861744 IC50 31.6 nM
C[C@@H](CO)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3934521 pIC50 31.62 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3ccc(N4CCOCC4)c(-n4cnc(C5CC5)c4)c3)c2c1 CHEMBL4859892 IC50 31.8 nM
CC(C)(CO)c1ccc(C(=O)Nc2cn3cc(-n4ccnc4)ccc3n2)cc1 CHEMBL2205635 IC50 32.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ncc3[nH]cnc3n2)n1 CHEMBL4759182 IC50 32.6 nM
Cc1ccc2cc(C(=O)Nc3cccc(-c4nncn4C(C)C)n3)[nH]c2c1 CHEMBL4855351 IC50 32.8 nM
C[C@H](CO)n1cnnc1-c1cccc(NC(=O)Nc2cc3ccccn3n2)n1 CHEMBL4796925 IC50 33.8 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(F)ccc3n2)cc1 CHEMBL2205627 IC50 34.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(-n4cnc(C5CC5)n4)c3)c2c1 CHEMBL4846492 IC50 37.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2[C@H](C)C(F)F)n1 CHEMBL4864439 IC50 37.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccc(-c4cn[nH]c4)cc3[nH]2)n1 CHEMBL4879378 IC50 37.5 nM
C[C@H](CO)n1cnnc1-c1cccc(NC(=O)Nc2nccc3ccccc23)n1 CHEMBL4764071 IC50 37.9 nM
Cn1cc(Cl)c2cnc(NC(=O)c3ccc([C@](C)(O)CO)cc3)cc21 CHEMBL3927617 IC50 38.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3cccc(-c4cn[nH]c4)c3[nH]2)n1 CHEMBL4878410 IC50 38.9 nM
CC(CCO)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3953259 pIC50 39.81 nM
CCn1cc(Cl)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)c(C)c3)cc21 CHEMBL3974873 IC50 41.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccccc3[nH]2)n1 CHEMBL4853834 IC50 41.4 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccccn2)n1 CHEMBL4776637 IC50 43.4 nM
COC[C@H](C)n1cnnc1-c1cccc(NC(=O)c2cn(C)nc2OC)n1 CHEMBL4867281 IC50 44.0 nM
C[C@H](CO)n1cnnc1-c1cccc(NC(=O)Nc2ccc3ccccc3n2)n1 CHEMBL4753203 IC50 47.4 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2nccc3ccccc23)n1 CHEMBL4763562 IC50 48.5 nM
COc1cc(-c2n[nH]c3ccc(-c4nncn4C(C)C)cc23)cc(-n2cnc(C3CC3)c2)c1 CHEMBL4878227 IC50 48.6 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)OC(C)(C)C(=O)N3)n1 CHEMBL5406106 IC50 49.0 nM
NCCNS(=O)(=O)c1ccc(-c2c[nH]c3ncccc23)s1 CHEMBL3330169 IC50 50.0 nM
c1cc(-c2n[nH]c3ccc(-c4nncn4C4CC4)cc23)cc(-n2cnc(C3CC3)c2)c1 CHEMBL4869497 IC50 50.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(-c4cnn(C5CCOCC5)c4)c3)c2c1 CHEMBL4861821 IC50 50.1 nM
CC[C@@H](C)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 CHEMBL3890544 pIC50 50.12 nM
Cc1ccc(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)c(F)c1 CHEMBL3891901 pIC50 50.12 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2cc3ccccc3cn2)n1 CHEMBL4749551 IC50 50.6 nM
c1cc(-c2n[nH]c3ccc(-c4nncn4C4CCCC4)cc23)cc(-n2cnc(C3CC3)c2)c1 CHEMBL4864119 IC50 54.1 nM
COc1ccc2cc(C(=O)Nc3cccc(-c4nncn4C(C)C)n3)[nH]c2c1 CHEMBL4870487 IC50 54.3 nM
CCn1ccc2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3894807 IC50 55.0 nM
Cc1ccc(-c2n[nH]c3ccc(-c4nncn4C(C)C)cc23)cc1-n1cnc(C2CC2)c1 CHEMBL4861520 IC50 56.9 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2cnc3ccccc3n2)n1 CHEMBL4778358 IC50 58.0 nM
Cn1c(Cl)c(Cl)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 CHEMBL3644051 IC50 60.0 nM
COCCn1cc(NC(=O)c2csc(-c3nncn3C(C)C)n2)cn1 CHEMBL4073198 EC50 60.0 nM
Cc1ccc(-c2ccc3c(ccc4sc5c(c43)NC[C@@H](C)NC5=O)n2)cn1 CHEMBL1231206 IC50 60.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(-n4cnc(C5CC5)c4)c3)c2c1 CHEMBL4856712 IC50 62.2 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)C(C)(C)CC(=O)N3C)n1 CHEMBL5401473 IC50 63.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(-c4cnn(C)c4)c3)c2c1 CHEMBL4861117 IC50 63.6 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccc(-c3cnn(C)c3)cn2)n1 CHEMBL4753312 IC50 64.2 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccc(-c3ccn(C)n3)cn2)n1 CHEMBL4744931 IC50 64.2 nM
COCCCn1cc(NC(=O)c2csc(-c3nncn3C(C)C)n2)cn1 CHEMBL4093878 EC50 65.0 nM
C[C@H](CO)n1cnnc1-c1cccc(NC(=O)c2cc3ccccc3[nH]2)n1 CHEMBL4850703 IC50 65.5 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ncc3ccccc3n2)n1 CHEMBL4750857 IC50 65.7 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccn[nH]2)n1 CHEMBL4796219 IC50 66.7 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccc(-c4cccnc4)cc3[nH]2)n1 CHEMBL4873038 IC50 68.5 nM
C[C@](O)(CO)c1ccc(C(=O)Nc2cc3c(ccn3C3CC3)cn2)cc1 CHEMBL3644043 IC50 69.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccc3ccccc3n2)n1 CHEMBL4795965 IC50 69.1 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 70.0 nM
CC(C)(O)c1ccc(C(=O)Nc2cn3cc(-n4ccnc4)ccc3n2)cc1 CHEMBL2205636 IC50 70.0 nM
c1cc(-c2n[nH]c3ccc(-c4nncn4C4CCC4)cc23)cc(-n2cnc(C3CC3)c2)c1 CHEMBL4862079 IC50 70.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ncnc3ccccc23)n1 CHEMBL4751918 IC50 71.0 nM
CCS(=O)(=O)Nc1cccc(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)c1 CHEMBL4286123 IC50 73.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccc(-c4cnn(C5CCOCC5)c4)cc3[nH]2)n1 CHEMBL4847905 IC50 73.7 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(C(N)=O)c3)c2c1 CHEMBL4855684 IC50 74.2 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cc(N4CCOCC4)cc(-n4cnc(C5CC5)c4)c3)c2c1 CHEMBL4865331 IC50 75.1 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2ccccc2F)n1 CHEMBL4451125 IC50 76.0 nM
CC(C)(O)c1ccc(C(=O)Nc2cc3c(ccn3CC3CC3)cn2)cc1 CHEMBL3644035 IC50 81.0 nM
C[C@H](CO)n1cnnc1-c1cccc(NC(=O)Nc2ncc3ccccc3n2)n1 CHEMBL4752034 IC50 81.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-c4ccccc4)ccc3n2)cc1 CHEMBL2205632 IC50 82.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2cc3ccccn3n2)n1 CHEMBL4740051 IC50 85.3 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)CCCC(=O)N3)n1 CHEMBL5430975 IC50 86.0 nM
Cc1c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)[nH]c2ccccc12 CHEMBL4848718 IC50 88.2 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3cccc(Cl)c3[nH]2)n1 CHEMBL4854772 IC50 89.6 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2cnccn2)n1 CHEMBL4754232 IC50 90.3 nM
CCOC(C)n1cc(-c2ccc3cc(C(=O)Nc4cccc(-c5nncn5C(C)C)n4)[nH]c3c2)cn1 CHEMBL4866091 IC50 91.1 nM
COc1ccccc1C(=O)Nc1cccc(-c2nncn2C)n1 CHEMBL4521694 IC50 92.0 nM
COc1nn(C)cc1C(=O)Nc1cccc(-c2nncn2[C@H](C)C(F)(F)F)n1 CHEMBL4863056 IC50 94.0 nM
COCCNc1ccnc(NC(=O)c2csc(-c3nncn3C(C)C)n2)c1 CHEMBL4086119 EC50 99.0 nM
O=C1Nc2cccc(n2)-c2nncn2C/C=C/COc2c(Br)cccc21 CHEMBL4457403 IC50 100.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)C(C)(C)CC(=O)N3)n1 CHEMBL5411561 IC50 102.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cnn(C)c2)n1 CHEMBL4640860 IC50 108.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2nc3ccccc3[nH]2)n1 CHEMBL4758606 IC50 110.8 nM
C[C@H](CO)n1cnnc1-c1cccc(NC(=O)Nc2cnc3ccccc3n2)n1 CHEMBL4761865 IC50 113.9 nM
O=C(Nc1cccc(-c2nncn2C2CC2)n1)c1cc2c(cc1F)OCc1cncn1-2 CHEMBL5411317 IC50 114.0 nM
Cn1c(Cl)c(Cl)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21 CHEMBL3936587 IC50 122.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2cc(C3CC3)n[nH]2)n1 CHEMBL4753192 IC50 123.7 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3cccnc3[nH]2)n1 CHEMBL4868746 IC50 125.1 nM
CC(C)(C)c1ccc(C(=O)Nc2cn3cc(CO)ccc3n2)cc1 CHEMBL2205630 IC50 129.0 nM
CC(C)n1cnnc1-c1nc(C(=O)Nc2cnn(C3COC3)c2)cs1 CHEMBL4081134 EC50 130.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)C2CN(c3ccccc3)CCO2)n1 CHEMBL4748155 IC50 130.0 nM
COc1nn(-c2ccncc2)cc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4636506 IC50 134.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 136.0 nM
COCCOc1ccnc(NC(=O)c2csc(-c3nncn3C(C)C)n2)c1 CHEMBL4064613 EC50 140.0 nM
Cc1cc(NC(=O)Nc2cccc(-c3nncn3C(C)C)n2)[nH]n1 CHEMBL4795694 IC50 141.9 nM
Cc1cc(NC(=O)Nc2cccc(-c3nncn3C(C)C)n2)nn1C CHEMBL4799364 IC50 142.7 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2[nH]c3ccccc3c2-c2ccoc2)n1 CHEMBL4846465 IC50 142.8 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(C(=O)Nc4cnn(C)c4)c3)c2c1 CHEMBL4860121 IC50 144.0 nM
CC(CO)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)OCC(=O)N3)n1 CHEMBL5399807 IC50 147.0 nM
NC1=NC(=O)/C(=C2\CCNC(=O)c3[nH]c(Br)cc32)N1 CHEMBL361708 IC50 150.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccccc3o2)n1 CHEMBL4846965 IC50 151.6 nM
CCc1cc(NC(=O)Nc2cccc(-c3nncn3C(C)C)n2)[nH]n1 CHEMBL4753690 IC50 152.7 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3cccc(-c4ccsc4)c3[nH]2)n1 CHEMBL4852337 IC50 153.3 nM
O=C1Nc2cccc(n2)-c2nncn2CCCOc2ccccc21 CHEMBL4470285 IC50 161.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3c(cc2F)CCCC(=O)N3C)n1 CHEMBL5421028 IC50 161.0 nM
C[C@H]1CCCn2cnnc2-c2cccc(n2)NC(=O)c2ccccc2O1 CHEMBL4565615 IC50 165.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cccc(-c3ncc[nH]3)c2)n1 CHEMBL4286022 IC50 170.0 nM
COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL281948 Kd apparent 182.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(NC(=O)c4ccc(C(F)(F)F)cc4)c3)c2c1 CHEMBL4851372 IC50 197.0 nM
O=C(O)CCCCCN1C(=O)/C(=C/c2ccc(-c3ccc(Br)cc3)o2)SC1=S CHEMBL2349206 IC50 200.0 nM
O=C(O)CCCN1C(=O)/C(=C/c2ccc(-c3ccc(Br)cc3)o2)SC1=S CHEMBL2349205 IC50 200.0 nM
CC(=O)Nc1cccc(Nc2ncc3cc(-c4cn[nH]c4)ccc3n2)c1 CHEMBL4215414 IC50 200.0 nM
CC(=O)Nc1cccc2cc(C(=O)Nc3cccc(-c4nncn4C(C)C)n3)[nH]c12 CHEMBL4846645 IC50 240.1 nM
c1cc(-c2n[nH]c3ccc(-c4nncn4C4CCCCC4)cc23)cc(-n2cnc(C3CC3)c2)c1 CHEMBL4878127 IC50 243.0 nM
COCCNC(=O)c1cccc(-c2n[nH]c3ccc(-c4nncn4C(C)C)cc23)c1 CHEMBL4871624 IC50 245.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccc(-c3cnn(C)c3)cc2)n1 CHEMBL4753801 IC50 245.4 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 248.0 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NCCN)s3)ccnc2[nH]1 CHEMBL3330172 IC50 251.0 nM
N#Cc1c[nH]c2c(C(N)=O)ccc(OC3CCNCC3)c12 CHEMBL3330171 IC50 251.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)C2CCCCO2)n1 CHEMBL4759397 pIC50 251.19 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2nn(C)c3ccccc23)n1 CHEMBL4787238 IC50 259.3 nM
Cc1ccc2nc(NC(=O)c3ccc(C(C)(C)C)cc3)sc2c1 CHEMBL2205625 IC50 260.0 nM
COc1ccc(-n2cnc(C3CC3)c2)cc1-c1n[nH]c2ccc(-c3nncn3C(C)C)cc12 CHEMBL4873179 IC50 270.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(C(=O)NC4CC4)c3)c2c1 CHEMBL4878217 IC50 271.0 nM
c1cc(-c2n[nH]c3ccc(-c4cn[nH]c4)cc23)cc(-n2cnc(C3CC3)c2)c1 CHEMBL4851478 IC50 274.6 nM
CCOC(C)n1cc(-c2cncc(-c3n[nH]c4ccc(-c5nncn5C(C)C)cc34)c2)cn1 CHEMBL4852798 IC50 277.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(-c4cccnc4)c3)c2c1 CHEMBL4851116 IC50 283.0 nM
CCS(=O)(=O)N1CCN(c2ccc(Nc3ncc(C(N)=O)c(NC4CC4)n3)cc2)CC1 CHEMBL3991929 Kd apparent 285.0 nM
O=C(Nc1cccc(-c2nncn2C2CC2)n1)c1cc(-c2cnn(C3CCC3)c2)cn(Cc2ccccc2F)c1=O CHEMBL5426009 IC50 289.0 nM
O=C(Nc1cccc(-c2nncn2C2CC2)n1)c1cc(-c2cnn(C(F)F)c2)cn(Cc2ccccc2F)c1=O CHEMBL5440185 IC50 290.89 nM
COc1ccccc1C(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4551282 IC50 299.0 nM
O=C(O)CCN1C(=O)/C(=C/c2ccc(-c3ccccc3F)o2)SC1=S CHEMBL2349212 IC50 300.0 nM
O=C(O)CCCN1C(=O)/C(=C/c2ccc(-c3ccccc3Cl)o2)SC1=S CHEMBL2348833 IC50 300.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)N(C)c2ccc3ccccc3n2)n1 CHEMBL4785979 IC50 318.6 nM
CC(C)n1cnnc1-c1cccc(NC(=O)Nc2ccncc2)n1 CHEMBL4745716 IC50 337.2 nM
CC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3ccc(Cl)c(Cl)c3)o2)SC1=S CHEMBL2346710 Ki 340.0 nM
O=C(O)CCCN1C(=O)/C(=C/c2ccc(-c3cc(Cl)ccc3Cl)o2)SC1=S CHEMBL2348837 IC50 350.0 nM
O=C(O)CCCN1C(=O)/C(=C/c2ccc(-c3cccc(Cl)c3)o2)SC1=S CHEMBL1688850 IC50 350.0 nM
C[C@@H]1CCCOc2ccccc2C(=O)Nc2cccc(n2)-c2nncn21 CHEMBL4537756 IC50 350.0 nM
CC(C)c1cc(NC(=O)Nc2cccc(-c3nncn3C(C)C)n2)[nH]n1 CHEMBL4788912 IC50 393.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2ccccc2)n1 CHEMBL3960900 pIC50 398.11 nM
CC(C)n1cnnc1-c1nc(C(=O)Nc2ccccn2)cs1 CHEMBL4105386 IC50 400.0 nM
C[C@@H]1CN(c2cc(-c3n[nH]c4ccc(OC5(C)CC5)cc34)ncn2)C[C@H](C)O1 CHEMBL4098877 IC50 428.0 nM
CC(C)OC(=O)Nc1cccc(-c2nncn2C(C)C)n1 CHEMBL4744430 IC50 473.1 nM
Cn1nc(C(F)(F)F)c2cc(C(=O)Nc3cccc(-c4nncn4C4CC4)n3)c(=O)[nH]c21 CHEMBL5407513 IC50 488.89 nM
CCOC(=O)c1c(O)nc2cccc3c2c1-c1ccccc1C3=O CHEMBL1345690 Ki 500.0 nM
O=C(O)CCCCCN1C(=O)/C(=C/c2ccc(-c3cccc(C(F)(F)F)c3)o2)SC1=S CHEMBL2349219 IC50 500.0 nM
CCCC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3ccc(Br)cc3)o2)SC1=S CHEMBL2349208 IC50 500.0 nM
CCC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3ccc(Br)cc3)o2)SC1=S CHEMBL2349207 IC50 500.0 nM
O=C(O)CCCN1C(=O)/C(=C/c2ccc(-c3c(Cl)cccc3Cl)o2)SC1=S CHEMBL2348839 IC50 500.0 nM
CCC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3cc(Cl)ccc3Cl)o2)SC1=S CHEMBL2348838 IC50 500.0 nM
O=C(O)CCCCCN1C(=O)/C(=C/c2ccc(-c3ccccc3Cl)o2)SC1=S CHEMBL2348834 IC50 500.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2nc3ccccc3s2)n1 CHEMBL4851548 IC50 506.0 nM
CC(C)CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nc3ccc(F)cc3s2)c1 CHEMBL3402508 IC50 520.0 nM
CCn1ccc2cnc(NC(=O)c3ccc([C@@](C)(O)CO)c(C)c3)cc21 CHEMBL3890514 IC50 528.0 nM
O=C(Nc1cccc(-c2n[nH]c3ccc(-c4nnc[nH]4)cc23)c1)c1ccc(C(F)(F)F)cc1 CHEMBL4869354 IC50 532.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cccc(C(N)=O)c2)n1 CHEMBL4293924 IC50 580.0 nM
CCn1cc(NC(=O)c2csc(-c3nncn3C(C)C)n2)cn1 CHEMBL4084596 EC50 600.0 nM
Nc1cccc(Nc2ncc3cc(-c4cn[nH]c4)ccc3n2)c1 CHEMBL4217652 IC50 600.0 nM
O=C(O)CCN1C(=O)/C(=C/c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)SC1=S CHEMBL2349217 IC50 650.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(S(C)(=O)=O)c3)c2c1 CHEMBL4865938 IC50 733.0 nM
O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccc(O)cc3c21 CHEMBL4284524 IC50 740.0 nM
CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccccc3n2C)n1 CHEMBL4878207 IC50 743.0 nM
CSCCC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3ccc(Cl)c(Cl)c3)o2)SC1=S CHEMBL2349203 IC50 750.0 nM
CCC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3cccc(Cl)c3)o2)SC1=S CHEMBL2348836 IC50 750.0 nM
O=C(O)CCN1C(=O)/C(=C/c2ccc(-c3ccccc3Cl)o2)SC1=S CHEMBL2348832 IC50 750.0 nM
CCCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nc3ccc(F)cc3s2)cc1 CHEMBL3402507 IC50 750.0 nM
CC(=O)N[C@H]1C[C@H]2O[C@@](C)([C@@H]1O)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4277459 IC50 770.0 nM
O=C1c2ccccc2CN1c1cccc(-c2nncn2CC2CCO2)n1 CHEMBL3955870 pIC50 794.33 nM
CCOC(=O)c1ccc(-c2ccc(/C=C3\SC(=S)N(C(CC(=O)O)C(C)=O)C3=O)o2)cc1 CHEMBL2349215 IC50 800.0 nM
CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cccc(-c4ccnn4C)c3)c2c1 CHEMBL4856252 IC50 855.0 nM
CNCc1ccc2nc(NC(=O)c3ccc(C(C)(C)C)cc3)cn2c1 CHEMBL2205631 IC50 870.0 nM
CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1N[C@H]1CC[C@H](CN(C)C)CC1 CHEMBL3688339 Kd apparent 878.0 nM
CC(=O)Nc1cccc(Nc2ncc3ccccc3n2)c1 CHEMBL4211961 IC50 900.0 nM
O=C1NCc2c1c1c3cc(O)ccc3[nH]c1c1[nH]c3ccccc3c21 CHEMBL4294912 IC50 943.9 nM
CCCCn1cnnc1-c1cccc(NC(=O)c2cc3c(C(F)(F)F)nn(C)c3[nH]c2=O)n1 CHEMBL5417367 IC50 978.0 nM
O=C(O)CC(C(=O)O)N1C(=O)/C(=C/c2ccc(-c3c(Cl)cccc3Cl)o2)SC1=S CHEMBL2349201 IC50 1000.0 nM
O=C(O)CCN1C(=O)/C(=C/c2ccc(-c3cccc(Cl)c3)o2)SC1=S CHEMBL2348835 IC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM