C[C@H](Nc1cc(-c2c(-c3cccc(C(F)(F)F)c3)nc(C3CCNCC3)n2C)ccn1)c1ccccc1 CHEMBL303144 IC50 0.1 nM
C[C@@H]1CCC[C@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cnn(CCN(C)C)c4)c4ccccc43)cn12 CHEMBL5174953 IC50 0.1 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(C(C)C)n4c3)c3ccccc32)cc1 CHEMBL5206328 IC50 0.2 nM
C[C@H]1CCCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cnn(CCN(C)C)c4)c4ccccc43)cn12 CHEMBL5202475 IC50 0.2 nM
CC(C)(C)N1CCC(c2cc(-c3ccc(F)cc3F)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 CHEMBL199679 IC50 0.25 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)cc1 CHEMBL5184542 IC50 0.4 nM
Cc1ccc(C(=O)NC2CC2)cc1-c1cc2cnn(-c3c(F)cccc3F)c2n(C)c1=O CHEMBL1089865 Kd 0.67 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCC(CO)CC5)n4c3)c3ccccc32)cc1 CHEMBL5197888 IC50 0.8 nM
C[C@H]1CCCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(OCCN(C)C)c4)c4ccccc43)cn12 CHEMBL5208103 IC50 1.3 nM
CC[C@@H](C)Nc1ncc(C(=O)Nc2cc(C(=O)NC)ccc2C)s1 CHEMBL258202 IC50 1.5 nM
CNc1noc2c(-c3ccc4c(N5CCOC[C@@H]5C)nncc4c3)c(C)ccc12 CHEMBL523374 Ki 1.8 nM
O=C(NCCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl)C1CCC(C(F)(F)F)CC1 CHEMBL221700 IC50 2.0 nM
O=C(NC1CC1)c1ccc(Cl)c(Nc2nncc3c2cnn3-c2c(F)cccc2F)c1 CHEMBL1082158 IC50 4.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cnn(-c2ncccc2C(F)(F)F)c1C CHEMBL2401979 IC50 4.0 nM
NC(=O)c1ccc(N(C(N)=O)c2c(F)cccc2F)nc1-c1ccc(F)cc1F CHEMBL1090090 Kd apparent 5.0 nM
CCc1c(OCc2ccc(F)cc2F)ncn(-c2cc(C(=O)NCCO)ccc2C)c1=O CHEMBL1795686 Ki 6.0 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1 CHEMBL103667 IC50 7.0 nM
C[S+]([O-])c1ccc(-c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)cc1 CHEMBL88486 IC50 8.1 nM
C[C@H](CS(C)(=O)=O)Nc1ncc2cc(Oc3ccc(F)cc3F)c(=O)n(C)c2n1 CHEMBL1232769 Kd 8.7 nM
CCOc1cc(N2CCN(C)CC2)ccc1Nc1ncc2cc(-c3cccc(NC(=O)c4cccc(C(F)(F)F)c4)c3)c(=O)n(C[C@H]3CCCO3)c2n1 CHEMBL5415503 Kd 9.4 nM
Oc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL278041 IC50 9.8 nM
CS(=O)(=O)c1ccc(-c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)cc1 CHEMBL316275 IC50 10.0 nM
C[C@]1(O)C[C@@H](c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)nccn32)C1 CHEMBL1091644 Kd apparent 10.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cnn(-c2ccccc2)c1N CHEMBL1290404 IC50 10.0 nM
Nc1c(C(=O)NCc2ccc(C(=O)NCCCC3CCCCC3)cc2)cnn1-c1ccccc1 CHEMBL4436748 IC50 10.0 nM
CNC(=O)c1ccc(C)c(Nc2nc(NC)nc3c2cnn3-c2ccccc2)c1 CHEMBL412281 IC50 12.0 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL10 IC50 12.0 nM
O=C1c2ccccc2C(=O)N1CCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl CHEMBL221547 IC50 15.0 nM
CCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NOC)ccc3C)c2c1C CHEMBL252128 IC50 15.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)c1cc2c(C(=O)C(=O)N(C)C)cn(C)c2cc1Cl CHEMBL514201 Kd 15.0 nM
Cc1cccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)c1C CHEMBL14212 IC50 15.2 nM
O=C(NCCN1CCOCC1)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)c(NC(=O)c4ccccc4)c3)cc1CC2 CHEMBL2316207 IC50 16.9 nM
Cc1ccc(C(=O)NCCO)cc1-n1cnc(OCc2ccc(F)cc2F)c(C)c1=O CHEMBL1795685 Ki 17.0 nM
CCNC(=O)[C@H](CCC1CCCCC1)NC(=O)c1ccc(CNC(=O)c2cnn(-c3ccccc3)c2N)cc1 CHEMBL4756586 IC50 17.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cnc(-c2ccccc2Cl)s1 CHEMBL2401978 IC50 18.0 nM
Cc1ccc(C(=O)NC2CC2)cc1Nc1ncnn2cc(C(=O)c3ccccc3)c(C)c12 CHEMBL1807446 IC50 19.0 nM
O=C1c2ccccc2C(=O)N1CCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccc(F)cc1Cl CHEMBL221595 IC50 20.0 nM
CONC(=O)c1ccc(C)c(Nc2nc(N(C)CC(C)(C)C)nc(N3CCCN(C)CC3)n2)c1 CHEMBL225088 IC50 22.0 nM
CC(C)(C)c1cc(NC(=O)NCc2ccccc2Sc2ccc3nnc(-c4ccccc4SCCO)n3c2)n(-c2ccc(O)c(Cl)c2)n1 CHEMBL1938400 IC50 23.0 nM
Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cc1 CHEMBL478649 Ki 24.0 nM
C[C@H](CS(C)(=O)=O)Nc1n[nH]c2nc(Oc3ccc(F)cc3F)ncc12 CHEMBL1236810 Kd 25.0 nM
O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(OC[C@H](O)CO)cc21 CHEMBL2152944 IC50 25.0 nM
COc1ccccc1Oc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCNCC2)n1 CHEMBL417804 IC50 25.0 nM
Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)(C)C)cn1 CHEMBL1088752 pKi 25.12 nM
Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cn1 CHEMBL1784172 pKi 25.12 nM
O=C(NCCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl)C1CCNCC1 CHEMBL221648 IC50 29.0 nM
CNCC(=O)NCCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl CHEMBL221246 IC50 29.0 nM
Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(NC3CCOCC3)nc21 CHEMBL1230122 Kd 29.0 nM
O=C(CC1CCCN1)NCCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl CHEMBL218661 IC50 31.0 nM
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1 CHEMBL255863 Kd 36.0 nM
Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3)nn3c2NC[C@@H](CO)C3)ccc1=O CHEMBL2170294 IC50 36.0 nM
CNC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1 CHEMBL1088751 Ki 40.0 nM
CS(=O)(=O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL280317 IC50 40.0 nM
NCC(=O)NCCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl CHEMBL376045 IC50 41.0 nM
COc1nccc(-c2c(-c3ccc(F)cc3)ncn2[C@H]2CC[C@H](O)CC2)n1 CHEMBL97162 IC50 44.0 nM
CS(=O)(=O)N1CCCC(NC(=O)[C@H](CCC2CCCCC2)NC(=O)c2ccc(CNC(=O)c3cnc4ccccn34)cc2)C1 CHEMBL4591082 IC50 45.1 nM
Nc1c(C(=O)c2cccc(OC[C@@H](O)CO)c2)cnn1-c1ccc(F)cc1 CHEMBL203567 Kd 50.0 nM
CN(C)CCN1CCN(C(=O)c2cc(C(C)(C)C)sc2NC(=O)Nc2cccc(Cl)c2Cl)CCC1=O CHEMBL1929238 IC50 50.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4c3OCCCN4)cc2)no1 CHEMBL4793380 IC50 50.0 nM
Cc1ccccc1N1C(=O)NCc2nc(Sc3ccc(F)cc3Cl)ccc21 CHEMBL128516 IC50 52.0 nM
CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2cccc(N)c2)n1 CHEMBL64040 IC50 52.0 nM
O=C1NCc2nc(Sc3ccc(F)cc3Cl)ccc2N1c1c(Cl)cccc1Cl CHEMBL128813 IC50 57.0 nM
Nc1c(C(=O)NCc2ncc(C(=O)NC3CC3)s2)cnn1-c1ccccc1 CHEMBL4444997 IC50 59.0 nM
CCCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NC4CC4)ccc3C)c2c1C CHEMBL1230065 IC50 62.0 nM
COC(=O)c1cc(Cl)c(N2C(=O)NCc3nc(Sc4ccc(F)cc4)ccc32)c(Cl)c1 CHEMBL129628 IC50 73.0 nM
O=c1ncn2nc(Sc3ccc(F)cc3F)ccc2c1-c1c(Cl)cccc1Cl CHEMBL119385 Kd 74.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(C(=O)N3CCOCC3)cc2)s1 CHEMBL2401994 IC50 81.0 nM
Cc1ccc(NC(=O)c2ccc(C)c(C(F)(F)F)c2)cc1C#Cc1nn([C@H]2CC[C@H](O)CC2)c2ncnc(N)c12 CHEMBL4798527 IC50 84.0 nM
COc1cccc(-c2nc3sccn3c2-c2ccnc(NCCCNS(=O)(=O)c3cccc(F)c3)n2)c1 CHEMBL5081210 IC50 95.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 97.0 nM
Cc1ccc(C(=O)N[C@@H](CC2CCCCC2)C(N)=O)cc1NC(=O)c1cnn(-c2ccccc2)c1N CHEMBL4443551 IC50 99.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(C(=O)N3CCCCC3)cc2)s1 CHEMBL2401995 IC50 109.0 nM
Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(Cc2ccncc2)cc1 CHEMBL288812 IC50 110.0 nM
Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(NC(CCO)CCO)nc21 CHEMBL1090089 Kd 120.0 nM
COc1cccc(-c2nc3sccn3c2-c2ccnc(NCCNS(=O)(=O)c3ccc(C(F)(F)F)cc3)n2)c1 CHEMBL5073858 IC50 120.0 nM
O=c1ccc(N(CCO)c2ccc(F)cc2Cl)nn1-c1ccccc1Cl CHEMBL221312 IC50 135.0 nM
Cc1ccc(C(=O)N[C@@H](CCC2CCCCC2)C(N)=O)cc1NC(=O)c1cnn(-c2ccccc2C)c1 CHEMBL4476320 IC50 144.0 nM
Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)C)cn1 CHEMBL1784173 pKi 158.49 nM
COc1cccc(CNC(=O)c2ccc(-c3cc(-c4nnc(C)o4)ccc3C)cc2)c1 CHEMBL271271 Ki 160.0 nM
CN1CCC(c2[nH]nc(-c3cccc(C(F)(F)F)c3)c2-c2ccncc2)CC1 CHEMBL1090512 IC50 164.0 nM
Cc1ccc(C(=O)N[C@@H](CCC2CCCCC2)C(N)=O)cc1NC(=O)c1ccc(-c2ccccc2Cl)s1 CHEMBL4462636 IC50 167.0 nM
O=C1NCc2nc(Sc3ccc(Cl)cc3Cl)ccc2N1c1c(Cl)cccc1Cl CHEMBL128440 IC50 190.0 nM
Cc1ccccc1-n1cc(C(=O)NCc2ncc(C(=O)N[C@@H](CCC3CCCCC3)C(N)=O)s2)cn1 CHEMBL4574467 IC50 191.0 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2Oc2ccc3c(cnn3CCO)c2)cc1 CHEMBL3991932 Kd apparent 192.0 nM
CCc1cccc(Cl)c1N1C(=O)NCc2nc(Sc3ccc(F)cc3)ccc21 CHEMBL129704 IC50 200.0 nM
CCc1nc(-c2cccc(C)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 CHEMBL363648 IC50 200.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 Kd 200.0 nM
Cc1ccc(C(=O)N[C@@H](CCC2CCCCC2)C(N)=O)cc1NC(=O)c1cnn(-c2ccccc2)c1 CHEMBL4473671 IC50 209.0 nM
CC(=O)c1cc(Cl)c(N2C(=O)NCc3nc(Sc4ccc(F)cc4)ccc32)c(Cl)c1 CHEMBL129775 IC50 210.0 nM
NS(=O)(=O)N1CCC(Nc2nccc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)n2)CC1 CHEMBL1773329 IC50 210.0 nM
NCCCN(c1ccc(=O)n(-c2ccccc2Cl)n1)c1ccccc1Cl CHEMBL221546 IC50 211.0 nM
Cc1cccc(Cl)c1N1C(=O)NCc2nc(Sc3ccc(F)cc3)ccc21 CHEMBL128756 IC50 220.0 nM
NC(=O)Oc1cc(Cl)c(N2C(=O)NCc3nc(Sc4ccc(F)cc4)ccc32)c(Cl)c1 CHEMBL129720 IC50 220.0 nM
Cc1ccc(C(=O)NCCO)cc1-n1cnc(OCc2ccc(F)cc2F)c(Cl)c1=O CHEMBL1738710 IC50 249.0 nM
COC(=O)c1cc(C)c(N2C(=O)NCc3nc(Sc4ccc(F)cc4)ccc32)c(Cl)c1 CHEMBL129375 IC50 250.0 nM
O=C1NCc2nc(Sc3ccc(F)cc3F)ccc2N1c1c(Cl)cccc1Cl CHEMBL92788 IC50 250.0 nM
NC(=O)[C@H](CCC1CCCCC1)NC(=O)c1ccc(CNC(=O)c2cnn(-c3ccccc3)c2N)cc1 CHEMBL3939964 IC50 250.0 nM
Cn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(F)cc2)n1 CHEMBL5419541 IC50 250.0 nM
CNCCOc1ccccc1C(C)(C)Nc1nccn(-c2cc(C(=O)NC3CC3)ccc2C)c1=O CHEMBL4792347 pIC50 251.19 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2cnccc2N2CCOCC2)s1 CHEMBL2402000 IC50 254.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccccc2Cl)s1 CHEMBL2401983 IC50 265.0 nM
COc1ccc(-c2ccc(C(=O)Nc3cc(C(=O)NC4CC4)ccc3C)s2)cc1 CHEMBL2401989 IC50 267.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(Cl)cc2)s1 CHEMBL2401981 IC50 270.0 nM
N#CCc1cnc(-c2ccc3ccccc3c2)n1-c1ccnc(N[C@H]2CCCN(C(=O)C3CC3)C2)n1 CHEMBL5396715 IC50 280.0 nM
CN(C)c1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1 CHEMBL4646628 Ki 320.0 nM
O=C(Cc1c(F)cccc1Cl)Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1 CHEMBL3310142 IC50 326.0 nM
NC(=O)[C@H](CCC1CCCCC1)NC(=O)c1cnc(CNC(=O)c2cnn(-c3ccccc3)c2)s1 CHEMBL4531946 IC50 328.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(CO)cc2)s1 CHEMBL2401991 IC50 332.0 nM
Cc1ccc(C(=O)NCCCC2CCCCC2)cc1NC(=O)c1ccc(-c2ccccc2Cl)s1 CHEMBL4578152 IC50 364.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL223360 Kd 370.0 nM
NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cnc(CNC(=O)c2cnn(-c3ccccc3)c2N)s1 CHEMBL4439959 IC50 370.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(O)cc2)s1 CHEMBL2401987 IC50 390.0 nM
O=C1NCc2nc(Sc3ccccc3Cl)ccc2N1c1c(Cl)cccc1Cl CHEMBL340687 IC50 393.0 nM
Fc1ccc(-c2n[nH]c(C3CCCNC3)c2-c2ccncc2)cc1 CHEMBL1091552 IC50 404.0 nM
Cc1ccc(-c2ccc(C(=O)Nc3cc(C(=O)NC4CC4)ccc3C)s2)cn1 CHEMBL2402001 IC50 409.0 nM
Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1 CHEMBL5416410 Kd 410.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 430.0 nM
Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCC4CC4)cc3)c2)o1 CHEMBL273158 Ki 440.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(C(=O)N(C)C)cc2)s1 CHEMBL2401993 IC50 441.0 nM
O=c1ccc(Sc2ccccc2F)nn1-c1ccccc1Cl CHEMBL373934 IC50 450.0 nM
Cc1ccccc1Nc1ccc(=O)n(-c2ccccc2Cl)n1 CHEMBL221791 IC50 450.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(F)cc2)s1 CHEMBL2401984 IC50 485.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(N)cc2)s1 CHEMBL2401988 IC50 492.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2cccnc2)s1 CHEMBL2401997 Kd 500.0 nM
c1ccc2cc(-c3nnc(N4CCNCC4)cc3-c3ccncc3)ccc2c1 CHEMBL4647072 IC50 500.0 nM
Fc1ccc(-c2n[nH]c(C3CCNCC3)c2-c2ccncc2)cc1 CHEMBL1091667 IC50 510.0 nM
O=C(O)c1cc(Cl)c(N2C(=O)NCc3nc(Sc4ccc(F)cc4)ccc32)c(Cl)c1 CHEMBL128414 IC50 530.0 nM
O=C1NCc2nc(Sc3ccc(F)cc3)ccc2N1c1ccccc1Cl CHEMBL338612 IC50 530.0 nM
Cc1ccc(C(=O)N[C@@H](CCC2CCCCC2)C(N)=O)cc1NC(=O)c1cnn(-c2ccccc2)c1C(F)(F)F CHEMBL4465031 IC50 550.0 nM
O=C(Cc1ccc(F)c(F)c1)N1CCC(Nc2ncc3c(N4CCOCC4)n[nH]c3n2)CC1 CHEMBL4762609 IC50 550.0 nM
Fc1ccc(-c2[nH]cc(C3=C[C@@H]4CCCN4CC3)c2-c2ccncc2)cc1 CHEMBL1209288 IC50 572.0 nM
COc1ccc(CNCCCN(c2ccc(=O)n(-c3ccccc3Cl)n2)c2ccccc2Cl)c(OC)c1OC CHEMBL374216 IC50 600.0 nM
CN(C)C(=O)[C@H](CCC1CCCCC1)NC(=O)c1ccc(CNC(=O)c2cnn(-c3ccccc3)c2N)cc1 CHEMBL4465838 IC50 660.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2cccc(Cl)c2)s1 CHEMBL2401982 IC50 679.0 nM
C[C@@H](NC(=O)c1ncnc(N)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1 CHEMBL3348923 Kd apparent 684.0 nM
CC(C)CCCNC(=O)c1ccc(CNC(=O)c2cnn(-c3ccccc3)c2N)cc1 CHEMBL4452908 IC50 730.0 nM
Cc1ccc(C(=O)N[C@@H](CCC(C)C)C(N)=O)cc1NC(=O)c1cnn(-c2ccccc2)c1N CHEMBL4540969 IC50 736.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Kd 760.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccncc2)s1 CHEMBL2401998 IC50 771.0 nM
Cn1cc(-c2ccnc3[nH]ncc23)c(-c2ccc(F)cc2)n1 CHEMBL5396363 IC50 780.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc2c(c1)OCCO2 CHEMBL4580637 IC50 784.0 nM
Cc1ccccc1Sc1ccc2c(n1)CNC(=O)N2c1c(Cl)cccc1Cl CHEMBL443285 IC50 800.0 nM
CN1CCN(CCNc2nccc(-c3c(-c4cccc(O)c4)nc4sccn34)n2)S1(=O)=O CHEMBL5087577 IC50 820.0 nM
Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(C#N)cc2)s1 CHEMBL2401990 IC50 830.0 nM
Cc1cc(Cl)ccc1-n1nc(Sc2ccc(F)cc2F)ccc1=O CHEMBL221071 IC50 850.0 nM
COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)on4)c3)c2cc1OC CHEMBL2029988 Kd apparent 872.0 nM
COc1ccccc1Nc1ccc(=O)n(-c2ccccc2Cl)n1 CHEMBL373767 IC50 920.0 nM
O=C1NCc2nc(Sc3ccc(F)cc3)ccc2N1c1c(Cl)cccc1C(F)(F)F CHEMBL129305 IC50 950.0 nM
Cc1ccc(C(=O)NC(C)(C)C(N)=O)cc1NC(=O)c1cnn(-c2ccccc2)c1N CHEMBL4440113 IC50 960.0 nM
Cc1ccccc1-n1cc(C(=O)NC(C)c2ccc(C(=O)N[C@@H](CCC3CCCCC3)C(N)=O)cc2)cn1 CHEMBL4440391 IC50 970.0 nM
Cc1cccc(C)c1Sc1ccc2c(n1)CNC(=O)N2c1c(Cl)cccc1Cl CHEMBL129174 IC50 980.0 nM
O=C1NCc2nc(NCc3ccccc3)ccc2N1c1c(Cl)cccc1Cl CHEMBL335878 IC50 980.0 nM
O=S(=O)(NCCCNc1nccc(-c2c(-c3cccc(O)c3)nc3sccn23)n1)c1cccc(F)c1 CHEMBL5086749 IC50 980.0 nM
O=c1ccc(Nc2ccccc2Cl)nn1-c1ccccc1Cl CHEMBL222109 IC50 990.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM