O=c1c(-c2ccc3ncccc3c2)c(Nc2cc[nH]n2)[nH]c2c(C3=CCCCC3)c(-c3ccccc3)nn12 CHEMBL4521249 IC50 4.0 nM
CCOC(=O)c1nnc(Nc2[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c(=O)c2-c2ccc3ncccc3c2)o1 CHEMBL4552959 IC50 4.0 nM
CCOc1ncc2cc(C3=CC4N=C(CCN5CCC(O)C5)N(C)C4C=C3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5199008 IC50 4.7 nM
COc1ccc(-c2c(Nc3cc[nH]n3)[nH]c3c(C4=CCCCC4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4558617 IC50 5.0 nM
O=c1c(-c2ccc(O)cc2)c(Nc2cc[nH]n2)[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4514699 IC50 7.0 nM
O=c1c(-c2ccc3ncccc3c2)c(Nc2cc[nH]n2)[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4582312 IC50 7.0 nM
COc1ccc(-c2c(Nc3ccccn3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4568226 IC50 7.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2c(c1)OCO2 CHEMBL4870597 IC50 8.0 nM
Cc1cc(=O)n2nc(C)c(-c3ccccc3)c2[nH]1 CHEMBL4860456 IC50 8.0 nM
COc1ccc(-c2c(Nc3ccon3)[nH]c3c(C4=CCCCC4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4585665 IC50 10.0 nM
CCNc1ccc2cn(-c3ccc4nn(C)cc4c3)c(=O)c(-c3ccc(Cl)cc3)c2n1 CHEMBL5185760 IC50 10.0 nM
CCOC(=O)n1ccc(Nc2[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c(=O)c2-c2ccc(OC)cc2)n1 CHEMBL4584451 IC50 11.0 nM
Cn1cc2cc(-n3cc4ccc(NCC(F)(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)ccc2n1 CHEMBL5177250 IC50 11.0 nM
COc1ccc(-c2c(Nc3cc[nH]n3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4559088 IC50 13.0 nM
CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 CHEMBL5078281 IC50 13.0 nM
Cn1cc2cc(-n3cc4ccc(OCC(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)ccc2n1 CHEMBL5187048 IC50 13.0 nM
COc1ccc(-c2c(Nc3ccccn3)[nH]c3c(C4=CCCCC4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4573938 IC50 14.0 nM
Cn1cc2cc(-n3cc4cnc(NCC(F)(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)ccc2n1 CHEMBL5178902 IC50 14.0 nM
CCNc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5415073 IC50 14.0 nM
CN1CCn2c(nc3ccc(-c4cc5cnc(C6CC6)nc5n(-c5ccc(OC(F)F)cc5)c4=O)cc32)C1 CHEMBL5399738 IC50 14.0 nM
Cc1cccc(-n2c(=O)nc(N(C)C)c3ccc(Cl)cc32)c1 CHEMBL5075691 IC50 16.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C(C)C)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5412125 IC50 17.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(CCOC)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5432232 IC50 17.0 nM
CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 CHEMBL5085027 IC50 18.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5401515 IC50 18.0 nM
CCOc1ncc2cc(-c3ccc4ncn(C)c4c3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5181969 IC50 19.5 nM
CCOc1ncc2cc(-c3ccc4nn5c(c4c3)CN(C)CC5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5405749 IC50 20.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(CC#N)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5434352 IC50 20.0 nM
CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 CHEMBL5078692 IC50 21.0 nM
Cc1nc2ccc(-n3cc4cnc(NCC(F)(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)cc2n1C CHEMBL5207988 IC50 21.0 nM
CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 CHEMBL5090022 IC50 22.0 nM
COc1ccc(-n2cc3cnc(NCC(F)(F)F)nc3c(-c3ccc(Br)cc3)c2=O)cc1 CHEMBL5170690 IC50 22.0 nM
CCOc1ccc2cn(-c3ccc4nn(C)cc4c3)c(=O)c(-c3ccc(Cl)cc3)c2n1 CHEMBL5207874 IC50 23.0 nM
CCOc1ncc2cc(-c3ccc4nn5c(c4c3)C(=O)N(C)CC5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5397124 IC50 23.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(CC3COC3)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5423083 IC50 23.0 nM
Cc1[nH]c2c(C3=CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4590059 IC50 25.0 nM
CCOc1ccc2c(=O)n(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5398750 IC50 26.0 nM
CC(C)Oc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5402991 IC50 27.0 nM
COc1ccc(-c2c(Nc3cnccn3)[nH]c3c(C4=CCCCC4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4529030 IC50 28.0 nM
CCOc1ccc2c(=O)n(-c3ccc4nn5c(c4c3)CN(C)CC5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5400994 IC50 28.0 nM
Cn1cnc2ccc(-n3cc4cnc(NCC(F)(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)cc21 CHEMBL5185699 IC50 31.0 nM
O=c1nc(NC2CC2)n2ccc(C(F)(F)F)cc2c1-c1cccc(O)c1F CHEMBL5439496 IC50 31.0 nM
Cn1cc2cc(-n3cc4ccc(OCC(F)(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)ccc2n1 CHEMBL5206988 IC50 32.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(O)cc1 CHEMBL4587880 IC50 33.0 nM
CCNc1ncc2cn(-c3ccc(OC)cc3)c(=O)c(-c3ccc(Br)cc3)c2n1 CHEMBL5206904 IC50 34.0 nM
CCOc1ccc2cc(-c3ccc4nn(C)cc4c3)c(=O)n(-c3ccc(OC(F)F)cc3)c2c1 CHEMBL5437430 IC50 34.0 nM
CN1CCn2c(nc3ccc(-c4cc5cnc(NCC(F)(F)F)nc5n(-c5ccc(OC(F)F)cc5)c4=O)cc32)C1 CHEMBL5427061 IC50 34.0 nM
O=c1nc(N2CC[C@@H](F)C2)c2ccc(Cl)cc2n1-c1ccccc1 CHEMBL5427280 IC50 36.0 nM
Cn1cnc2ccc(-c3cc4cnc(NCC(F)(F)F)nc4n(-c4ccc(OC(F)F)cc4)c3=O)cc21 CHEMBL5173547 IC50 36.5 nM
CN1CCn2c(nc3ccc(-c4cc5cnc(OCC(F)F)nc5n(-c5ccc(OC(F)F)cc5)c4=O)cc32)C1 CHEMBL5426003 IC50 37.0 nM
CCOc1ncc2nc(-c3ccc4nn(C)cc4c3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5432694 IC50 39.0 nM
O=c1nc(NC2CC2)n2ccc(C(F)(F)F)cc2c1-c1cccnc1F CHEMBL5407700 IC50 40.0 nM
CNc1nc(=O)c(-c2cccc(F)c2)c2cc(C(F)(F)F)ccn12 CHEMBL5411162 IC50 42.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2[nH]cnc2c1 CHEMBL4549681 IC50 45.0 nM
CNc1nc(=O)c(-c2ccccc2F)c2cc(C(F)(F)F)ccn12 CHEMBL5407969 IC50 45.0 nM
O=c1c(-c2ccc(Br)cc2)c2nc(NCC(F)(F)F)ncc2cn1-c1ccc2ncccc2c1 CHEMBL5183776 IC50 46.0 nM
O=c1nc(NC2CC2)n2ccc(C(F)(F)F)cc2c1-c1cccc(F)c1 CHEMBL5425116 IC50 46.0 nM
CCCNc1ncc2cn(-c3ccc(OC)cc3)c(=O)c(-c3ccc(Br)cc3)c2n1 CHEMBL5176577 IC50 48.0 nM
CNc1nc(=O)c(-c2ccccc2Cl)c2cc(C(F)(F)F)ccn12 CHEMBL5414561 IC50 49.0 nM
CNc1nc(=O)c(-c2ccccc2Cl)c2cc(C(F)F)ccn12 CHEMBL5393870 IC50 49.0 nM
Cn1cc2cc(-n3cc4cnc(NCC(F)(F)F)nc4c(-c4ccc(OC(F)F)cc4)c3=O)ccc2n1 CHEMBL5416039 IC50 50.0 nM
COc1ccc2oc3cc(C)[n+]([O-])c(-c4ccc(C)cc4)c3c2c1 CHEMBL1573144 IC50 51.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(Cl)cc3)c2n1 CHEMBL5425823 IC50 51.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4483464 IC50 52.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C(C)=O)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5440991 IC50 52.0 nM
CNc1nc(=O)c(-c2ccccc2Cl)c2cc(C3CC3)ccn12 CHEMBL5421399 IC50 53.0 nM
COc1ccc(-n2cc3cnc(NCC4CC4)nc3c(-c3ccc(Br)cc3)c2=O)cc1 CHEMBL5180626 IC50 54.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(O)cc1 CHEMBL4560666 IC50 57.0 nM
CNc1nc(=O)c(-c2cccc(C)c2)c2cc(C(F)(F)F)ccn12 CHEMBL5401688 IC50 60.0 nM
CCOc1ccc2cc(-c3ccc4c(c3)C3(CC3)CO4)c(=O)n(-c3ccc(OC(F)F)cc3)c2c1 CHEMBL5412431 IC50 63.0 nM
COc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5393737 IC50 64.0 nM
CNc1nc(=O)c(-c2ccccc2)c2cc(C(F)(F)F)ccn12 CHEMBL5413150 IC50 65.0 nM
CNc1nc(=O)c(-c2c(F)cccc2F)c2cc(C(F)(F)F)ccn12 CHEMBL5419023 IC50 65.0 nM
Cc1[nH]c2c(C3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4561247 IC50 66.0 nM
CCn1cc2cc(NC(=O)c3cc(C4CC4)nc4c3cnn4CC)ccc2n1 CHEMBL5435278 IC50 68.0 nM
CNc1nc(=O)c(-c2ccccc2C(C)C)c2cc(C(F)(F)F)ccn12 CHEMBL5439586 IC50 68.0 nM
CCOc1ncc2cc(-c3ccc(OC)cc3C)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5192122 IC50 70.1 nM
CCOc1ncc2cc(-c3cc4c5c(c3)ncn5CCO4)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5419227 IC50 72.0 nM
CCn1ncc2c(C(=O)Nc3ccc4nn(C)cc4c3)cc(C3CC3)nc21 CHEMBL5426479 IC50 78.0 nM
O=c1c(-c2ccc(Cl)cc2)c2nc(NCC(F)(F)F)ncc2cn1-c1ccc2ncccc2c1 CHEMBL5205028 IC50 79.0 nM
CC(C)Nc1nc(=O)c(-c2ccccc2F)c2cc(C(F)(F)F)ccn12 CHEMBL5405042 IC50 80.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2[nH]c(N)nc2c1 CHEMBL4582351 IC50 83.0 nM
CCn1ncc2c(C(=O)Nc3ccc4nn(C)c(C)c4c3)cc(C3CC3)nc21 CHEMBL5399691 IC50 90.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4552037 IC50 97.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1C1CC1 CHEMBL4571843 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccccc1 CHEMBL4522713 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1C1CCCC1 CHEMBL4546633 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1cccc(N)c1 CHEMBL4527921 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1N1CCOCC1 CHEMBL4561650 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccncc1 CHEMBL4525301 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(C(N)=O)cc1 CHEMBL4567650 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(N)cc1 CHEMBL4542083 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(O)nc1 CHEMBL4562374 IC50 100.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1N1CCC(O)CC1 CHEMBL4569602 IC50 100.0 nM
CCc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(OC)cc1 CHEMBL4514719 IC50 100.0 nM
COc1ccc(-c2c(CC#N)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4561105 IC50 100.0 nM
COc1ccc(-c2c(C#N)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4583730 IC50 100.0 nM
COc1ccc(-c2c(C(N)=O)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4568510 IC50 100.0 nM
Cc1[nH]c2c(N3CCC(F)(F)C3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4527123 IC50 100.0 nM
Cc1[nH]c2c(N3CCC(F)(F)C3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2nccn2c1 CHEMBL4572719 IC50 100.0 nM
Cc1c(-c2ccc3ncccc3c2)c(=O)n2nc(-c3ccccc3)c(-c3ccccc3)c2n1C CHEMBL4546944 IC50 100.0 nM
O=c1c(-c2ccc3ncccc3c2)c(CO)[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4521225 IC50 100.0 nM
O=c1c(-c2ccc3ncccc3c2)c(Cn2cccn2)[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4588181 IC50 100.0 nM
O=c1c(-c2ccc3ncccc3c2)c(Cc2ncn[nH]2)[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4580282 IC50 100.0 nM
O=C1CN(Cc2[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c(=O)c2-c2ccc3ncccc3c2)C(=O)N1 CHEMBL4538283 IC50 100.0 nM
CNC(=O)c1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4522257 IC50 100.0 nM
CCC(=O)Nc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4551093 IC50 100.0 nM
O=C(NCCO)c1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4573728 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncnc(N)c2c1 CHEMBL4573526 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2nccnc2c1 CHEMBL4555060 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(OCC(=O)N(C)C)cc1 CHEMBL4553872 IC50 100.0 nM
COc1ccc(-c2c(C)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cn1 CHEMBL4567243 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2occc2c1 CHEMBL4483341 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2nnccc2c1 CHEMBL4546271 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1C1=CCC(=O)CC1 CHEMBL4516541 IC50 100.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1C1=CCC(O)CC1 CHEMBL4578643 IC50 100.0 nM
COc1ccc(-c2c(Cn3cnnn3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4576190 IC50 100.0 nM
COc1ccc(-c2c(Cn3ncnn3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4558233 IC50 100.0 nM
COc1ccc(-c2c(CNC(=O)[C@@H](N)C(C)C)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4568635 IC50 100.0 nM
COc1ccc(-c2c(Nc3ccccc3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4530602 IC50 100.0 nM
Cn1cc2cc(-n3cc4ccc(CCC(F)(F)F)nc4c(-c4ccc(Cl)cc4)c3=O)ccc2n1 CHEMBL5183514 IC50 101.0 nM
Cc1c(-c2ccc(O)cc2)c(=O)n2nc(-c3ccccc3)c(N3CCCCC3)c2n1C CHEMBL4856769 IC50 102.0 nM
CNc1nc(=O)c(-c2cccc(Cl)c2)c2cc(C(F)(F)F)ccn12 CHEMBL5399741 IC50 107.0 nM
COc1ccc(-n2cc3cnc(NCC(F)(F)F)nc3c(-c3ccc(Cl)cc3)c2=O)cc1 CHEMBL5208553 IC50 113.0 nM
O=c1nc(NCC(F)F)n2ccc(C(F)(F)F)cc2c1-c1ccccc1F CHEMBL5433315 IC50 119.0 nM
O=c1nc(NC2CC2)n2ccc(C(F)(F)F)cc2c1-c1ccccc1F CHEMBL5398803 IC50 120.0 nM
O=c1nc(NC2CCC2)n2ccc(C(F)(F)F)cc2c1-c1ccccc1F CHEMBL5431494 IC50 121.0 nM
COc1ccc2oc3cc(C)[n+]([O-])c(-c4ccc(Cl)cc4)c3c2c1 CHEMBL1449820 IC50 122.0 nM
CCn1ncc2c(C(=O)Nc3ccc(OC)cc3)cc(C3CC3)nc21 CHEMBL5419203 IC50 130.0 nM
CCOc1ncc2cc(-c3ccc4nc5n(c4c3)CCN(C)C5)c(=O)n(-c3ccc(OC)nc3)c2n1 CHEMBL5430139 IC50 132.0 nM
CNc1nc(=O)c(-c2ccccc2Cl)c2cc(C)ccn12 CHEMBL5402493 IC50 143.0 nM
COc1ccc(-c2c3c(cc(C)[n+]2[O-])oc2ccc(OC)cc23)cc1 CHEMBL1362902 IC50 145.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1cscn1 CHEMBL4531472 IC50 158.0 nM
Cc1[nH]c2c(C3=CCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4551583 IC50 159.0 nM
CCn1ncc2c(C(=O)Nc3ccc4ncsc4c3)cc(C3CC3)nc21 CHEMBL5422027 IC50 172.0 nM
O=c1nc(N[C@H]2C[C@H](O)C2)n2ccc(C(F)(F)F)cc2c1-c1ccccc1F CHEMBL5438211 IC50 192.0 nM
CNc1nc(=O)c(-c2cccc(C#N)c2)c2cc(C(F)(F)F)ccn12 CHEMBL5422860 IC50 199.0 nM
CCn1ncc2c(C(=O)Nc3ccc4ncn(C)c4c3)cc(C3CC3)nc21 CHEMBL5405041 IC50 205.0 nM
CN(C)CCc1nnc2cc(-c3ccccc3)c3cc(Cl)ccc3n12 CHEMBL337420 IC50 225.0 nM
COc1ccc(N2Cc3c(C)nc(NCC4CC4)nc3C3(CCN(Cc4ccccc4F)C3)C2=O)cc1 CHEMBL5188451 IC50 250.0 nM
CNc1cc(=O)n(-c2ccccc2Cl)c2nc(C(F)(F)F)ccc12 CHEMBL5436215 IC50 252.0 nM
Cc1cc(=O)n2nc(-c3ccccc3)c(C3=CCCCC3)c2[nH]1 CHEMBL4865263 IC50 260.0 nM
Cc1cc(=O)n2nc(-c3ccccc3)c(N3CCCCC3)c2[nH]1 CHEMBL4877839 IC50 260.0 nM
CNc1nc(=O)n(-c2ccccc2Cl)c2cc(C(F)(F)F)sc12 CHEMBL5420391 IC50 268.0 nM
O=c1cc(Nc2cc[nH]n2)[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4875209 IC50 270.0 nM
CCn1ncc2c(C(=O)Nc3ccc4ncccc4c3)cc(C3CC3)nc21 CHEMBL5409231 IC50 277.0 nM
COc1ccc2c(=O)c(C)c(-c3ccnc(-c4ccc(OC(F)(F)F)cc4)c3)[nH]c2c1 CHEMBL3740357 IC50 283.0 nM
CCn1ncc2c(C(=O)Nc3ccc4c(c3)ncn4C)cc(C3CC3)nc21 CHEMBL5406558 IC50 303.0 nM
COc1ccc(N2Cc3cnc(NCC4CC4)nc3C3(CCN(Cc4ccccc4F)C3)C2=O)cc1 CHEMBL5196666 IC50 320.0 nM
CN1CCn2c(nc3ccc(-c4cc5cnc(N6CCC6)nc5n(-c5ccc(OC(F)F)cc5)c4=O)cc32)C1 CHEMBL5413811 IC50 324.0 nM
COc1ccc(-n2cc3cnc(NCCC(F)(F)F)nc3c(-c3ccc(Br)cc3)c2=O)cc1 CHEMBL5175314 IC50 325.0 nM
CNc1nc(=O)c(-c2ccc(C)cc2)c2cc(C(F)(F)F)ccn12 CHEMBL5413791 IC50 347.0 nM
CCOc1ncc2cc(-c3ccc4c(c3)nc3n4CCN(C)C3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1 CHEMBL5418094 IC50 394.0 nM
CC(C)n1ncc2c(C(=O)Nc3ccc4nn(C)cc4c3)cc(C3CC3)nc21 CHEMBL5400313 IC50 403.0 nM
COc1ccc(N2Cc3cnc(NCC4CC4)nc3C3(CCN(Cc4cnc(N)s4)C3)C2=O)cc1 CHEMBL5183201 IC50 410.0 nM
CCn1ncc2c(C(=O)Nc3ccc4[nH]ncc4c3)cc(C3CC3)nc21 CHEMBL5413291 IC50 469.0 nM
COc1ccc(N2Cc3cnc(NCC4CC4)nc3C3(CCN(Cc4ccsc4)C3)C2=O)cc1 CHEMBL5183797 IC50 510.0 nM
COc1ccc(N2Cc3cnc(NCC4CC4)nc3C3(CCN(Cc4ccon4)C3)C2=O)cc1 CHEMBL5184221 IC50 530.0 nM
O=c1nc(N2CCCC2)n2ccc(C(F)(F)F)cc2c1-c1ccccc1F CHEMBL5436630 IC50 531.0 nM
COc1ccc(N2Cc3cnc(NCC4CC4)nc3C3(CCN(Cc4cscn4)C3)C2=O)cc1 CHEMBL5201203 IC50 610.0 nM
Cc1cc(=O)n2nc(-c3ccccc3)c(C3CCCCC3)c2[nH]1 CHEMBL4875322 IC50 660.0 nM
Cc1cc(=O)n2nc(-c3ccccc3)c(C3CCCC3)c2[nH]1 CHEMBL4866271 IC50 680.0 nM
COc1ccc(N2Cc3cnc(NCC4CC4)nc3C3(CCN(Cc4cc[nH]n4)C3)C2=O)cc1 CHEMBL5198564 IC50 690.0 nM
CCN(C)c1nc(=O)[nH]c2cc(Cl)ccc12 CHEMBL5082697 IC50 740.0 nM
COc1ccc(-c2nn3c(=O)c(-c4ccc5ncccc5c4)c(C)[nH]c3c2-c2ccccc2)cc1 CHEMBL4581059 IC50 1000.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccc([N+](=O)[O-])cc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4518014 IC50 1000.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1cc[nH]c(=O)c1 CHEMBL4521572 IC50 1000.0 nM
Cc1[nH]c2c(N3CCCCC3)c(-c3ccccc3)nn2c(=O)c1-c1ccc(S(C)(=O)=O)cc1 CHEMBL4536984 IC50 1000.0 nM
CC(=O)Nc1ccc(-c2c(C)[nH]c3c(N4CCCCC4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4530824 IC50 1000.0 nM
O=C1CNC(=O)N1Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4545746 IC50 1000.0 nM
O=C1NCCN1Cc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4552902 IC50 1000.0 nM
O=C(Nc1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1)C1CC1 CHEMBL4544964 IC50 1000.0 nM
O=C(NCc1cc[nH]n1)c1[nH]c2c(-c3ccccc3)c(-c3ccccc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4519593 IC50 1000.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3cccc(Cl)c3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4518745 IC50 1000.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccc(Cl)cc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4527632 IC50 1000.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccncc3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4578258 IC50 1000.0 nM
COc1ccc(-c2nn3c(=O)c(-c4ccc5ncccc5c4)c(C)[nH]c3c2-c2ccccc2)cn1 CHEMBL4563051 IC50 1000.0 nM
Cc1[nH]c2c(-c3ccccc3)c(-c3ccnc(Cl)c3)nn2c(=O)c1-c1ccc2ncccc2c1 CHEMBL4543000 IC50 1000.0 nM
COc1cc(-c2nn3c(=O)c(-c4ccc5ncccc5c4)c(C)[nH]c3c2-c2ccccc2)ccn1 CHEMBL4589253 IC50 1000.0 nM
O=c1c(-c2ccc3ncccc3c2)cn(CCn2cnnn2)c2c(-c3ccccc3)c(-c3ccccc3)nn12 CHEMBL4546541 IC50 1000.0 nM
NCCn1cc(-c2ccc3ncccc3c2)c(=O)n2nc(-c3ccccc3)c(-c3ccccc3)c12 CHEMBL4535134 IC50 1000.0 nM
COc1ccc(-c2c(Oc3cccnn3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4539716 IC50 1000.0 nM
COc1ccc(-c2c(Oc3ccccc3)[nH]c3c(-c4ccccc4)c(-c4ccccc4)nn3c2=O)cc1 CHEMBL4557822 IC50 1000.0 nM