Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(NC2CC2)n1 CHEMBL4793203 IC50 0.02 nM
Cc1nc2nonc2c(N)c1Cn1ccc(-c2cccc(C(F)(F)F)n2)n1 CHEMBL4746798 IC50 0.028 nM
COc1cc(C(F)(F)F)ccc1Cc1c(C)nc2nonc2c1N CHEMBL4754865 IC50 0.066 nM
Cc1nc2ncnn2c(N)c1Cc1ccc(Br)c(OC(F)F)n1 CHEMBL4781133 IC50 0.13 nM
Cc1nc2nonc2c(N)c1CN1CCC(OC(F)(F)F)CC1 CHEMBL4789143 IC50 0.56 nM
Cc1nc(C(F)(F)F)ccc1COc1cc(Cl)c2cc(CC(=O)O)sc2c1Cl CHEMBL4785875 IC50 1.7 nM
C[C@@H](O)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](CN)NC(=O)[C@H](CO)NC(=O)CN)C(N)=O CHEMBL4741413 IC50 6.0 nM
O=C(O)c1ccc2oc(SCc3ccc(Cl)cc3Cl)nc2c1 CHEMBL4791105 IC50 8.6 nM
Cc1nc(Cl)nc(N)c1CCC1CCN(C(=O)[C@H](C)NC(=O)c2cn[nH]c2C)CC1 CHEMBL4741187 IC50 54.4 nM
C[C@H](NC(=O)c1ccn(C)n1)C(=O)N1CCC(CCc2c(N)nc(N)nc2Cl)CC1 CHEMBL4741216 IC50 68.9 nM
Cc1nc(C(F)(F)F)nc(N)c1CCC1CCN(C(=O)[C@H](C)NC(=O)c2ccnn2C)CC1 CHEMBL4756266 IC50 69.5 nM
Cc1nc(N)c(CCC2CCN(C(=O)[C@H](C)NC(=O)c3cnc(C)s3)CC2)c(Cl)n1 CHEMBL4760639 IC50 96.4 nM
COC(=O)N[C@@H](C)C(=O)N1CCC(CCc2c(N)nc(C)nc2Cl)CC1 CHEMBL4753838 IC50 149.0 nM
C[C@H](NC(=O)C1CC1)C(=O)N1CCC(CCc2c(N)nc(N)nc2Cl)CC1 CHEMBL4742847 IC50 192.0 nM
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cn1cc(CCCc2ccccc2)nn1)NC(=O)[C@H](CO)NC(=O)CN)C(N)=O CHEMBL3589129 IC50 700.0 nM