CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)N[C@@H]2CCN(C)C2)n1 CHEMBL5412684 Ki 0.3 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)N[C@@H]2CCNC2)n1 CHEMBL5435583 pKi 0.3162 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)C34CCC(C(F)(F)F)(CC3)CC4)C[C@H]2CC)c(C(=O)N[C@@H]2CCN(C)C2)n1 CHEMBL5414709 Kb 0.34 nM
CCOc1ccccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCC3)C[C@H]2CC)c(C(=O)N[C@@H]2CN3CCC2CC3)n1 CHEMBL5414447 Kb 0.34 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCN(C)C)n1 CHEMBL5432648 Ki 0.39 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCNC)n1 CHEMBL5414552 Ki 0.47 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCCC3)C[C@H]2CC)c(C(=O)N[C@@H]2CCN(C)C2)n1 CHEMBL5396357 Ki 0.63 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCN(C)C)c1F CHEMBL5417272 Ki 0.9 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCNC)c1 CHEMBL5424729 Ki 0.96 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCN)c1 CHEMBL5394322 Ki 1.1 nM
CCOc1ccccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCC3)C[C@H]2CC)c(C(=O)N[C@@H]2CCN(C)C2)n1 CHEMBL5406402 pKi 1.259 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCC3)C[C@H]2CC)c(C(=O)N[C@@H]2CCN(C)C2)n1 CHEMBL5422885 Kb 1.4 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCN(C)C)c1 CHEMBL5415832 Ki 1.5 nM
CCOc1ccccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCCN)c1 CHEMBL5401503 pKi 1.585 nM
CCOc1ccccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCC3)C[C@H]2CC)c(C(=O)NC2CCN(C)CC2)n1 CHEMBL5438739 pKi 1.585 nM
CCOc1ccccc1-c1ccc(N2CCN(C(=O)c3ccc(C(F)(F)F)cc3Cl)C[C@H]2CC)c(C(=O)NCCN)c1 CHEMBL5421498 pKi 1.995 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCC3)C[C@H]2CC)c(C(=O)NC2CCN(C)CC2)n1 CHEMBL5403170 Kb 2.1 nM
CCOc1ncccc1-c1ccc(N2CCN(C(=O)C3(C(F)(F)F)CCC3)C[C@H]2CC)c(C(=O)N[C@@H]2CN3CCC2CC3)n1 CHEMBL5397644 pKi 3.981 nM
CCOc1ccccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3Cl)C[C@H]2CC)c(C(=O)NCCN)c1 CHEMBL5405192 Ki 4.8 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(-c2ccccc2Cl)cc1C(=O)NCCN CHEMBL5435301 pKi 19.95 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(C(F)(F)F)cc1CN CHEMBL5431712 Kb 20.0 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(C(F)(F)F)cc1C(=O)NCCN CHEMBL5435859 Kb 23.0 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(-c2ccccc2C#N)cc1C(=O)NCCN CHEMBL5396826 Ki 25.0 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(C(F)(F)F)cc1CNC[C@H](C)O CHEMBL5405251 Kb 26.0 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(-c2cccc(F)c2Cl)cc1C(=O)NCCN CHEMBL5434090 Ki 36.0 nM
CC[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(-c2ccccc2F)cc1C(=O)NCCN CHEMBL5438731 Ki 47.0 nM
C[C@@H]1CN(C(=O)c2ccc(C(F)(F)F)cc2Cl)CCN1c1ccc(C(F)(F)F)cc1CN CHEMBL5403315 Kb 300.0 nM
CC1CN(C(=O)c2ccc(Cl)cc2Cl)CCN1c1ccc(C(F)(F)F)cc1CN CHEMBL5394802 Kb 390.0 nM
NCc1cc(C(F)(F)F)ccc1N1CCN(C(=O)c2ccc(Cl)cc2Cl)CC1 CHEMBL5422801 Kb 490.0 nM
CC1CN(c2ccc(C(F)(F)F)cc2CN)CCN1C(=O)c1ccc(Cl)cc1Cl CHEMBL5416396 Kb 830.0 nM